CTO: Core Ontology of Clinical Trials

Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable investigations run by robot scientists such as ADAM (King et al, Science, 2009)

has super-classes: role^c
has sub-classes: investigation collaborator role^c, investigator role^c, responsible party role^c

investigation collaborator role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000402

A secondary sponsor may serve as a collaborator role. However, a collaborator may not serve as a secondary sponsor role.

has super-classes: investigation agent role^c

investigational molecular entity^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000108

has super-classes: molecular entity^c

investigator^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000293

has super-classes: Homo sapiens^c
has sub-classes: clinical investigator^c

investigator role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000390

has super-classes: investigation agent role^c
has sub-classes: principal investigator role^c, sponsor investigator role^c

Iranian registry of clinical trials^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000009

has super-classes: primary registry^c

Iranian registry of clinical trials identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000013

has super-classes: Clinical Trial Registry Identifier^c

Japan clinical trial identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000209

has super-classes: Clinical Trial Registry Identifier^c
has sub-classes: JMACCT clinical trial identifier^c, UMIN-CTR clinical trial identifier^c, jRCT clinical trial identifier^c

JAPIC clinical trial identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000210

has super-classes: Clinical Trial Registry Identifier^c

JAPIC clinical trials registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000019

has super-classes: primary registry^c

JMACCT clinical trial identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000211

has super-classes: Japan clinical trial identifier^c

JMACCT clinical trials registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000025

has super-classes: primary registry^c

jRCT clinical trial identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000054

has super-classes: Japan clinical trial identifier^c

Korean clinical trials registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000041

has super-classes: primary registry^c

lay title of clinical trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000218

has super-classes: title of clinical trial^c

Lebanese clinical trials registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000023

has super-classes: primary registry^c

Lebanese clinical trials registry identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000056

has super-classes: Clinical Trial Registry Identifier^c

legal person role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OMRSE_00000038

We are aware of the fact that Wikipedia's definition differs from ours by saying that "Legal personality (...) is the characteristic of a non-living entity regarded by law to have the status of personhood" (http://en.wikipedia.org/wiki/Legal_personality) However, Shaw explicates: "In any legal system, certain entities, whether they be individuals or companies, will be regarded as possessing rights and duties enforceable at law. Thus an individual may prosecute or be prosecuted for assault and a company can sue for breach of contract. They are able to do this because the law recognises them as 'legal persons' possessing the capacity to have and to maintain certain rights, and being subject to perform specific duties. (...) In municipal law individuals, limited companies and public corporations are recognized as each possessing a distinct legal personality, the terms of which are circumscribed by the relevant legislation" (Shaw MN: International Law. Sixth Edition. Cambridge University Press, Cambridge, 2008). We hold that Shaw's position is ontological more prolific since it not only allows to explain how groups of individuals become recognized as unities at law, but also how different individuals can hold different legal personality roles (always against the context of one legal system). The latter will proof useful when dealing with the representing comatous patients or minorsat law in ontologies.

has super-classes: role in human social processes^c

longitudinal study design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OMIABIS_0001019

has super-classes: study design^c
has sub-classes: cohort study design^c

male^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PATO_0000384

has super-classes: phenotypic sex^c

Mammalia^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCBITaxon_40674

has super-classes: Vertebrata <vertebrates>^c
has sub-classes: Homo sapiens^c

masking design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000005

has super-classes: study design^c
has sub-classes: double blinded design^c, open blinded design^c, single blinded design^c

material entity^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000040

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: independent continuant^c
has sub-classes: chemical entity^c, device^c, drug product^c, fiat object part^c, medical device ^c, molecular entity^c, object^c, object aggregate^c, organization^c, root^c
is disjoint with: immaterial entity^c

maximum age value specification^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0002557

has super-classes: value specification^c

medical condition^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000282

has super-classes: realizable entity^c
has sub-classes: Condition or Disease under Study^c

medical device ^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/ERO_0001092

has super-classes: material entity^c

medical intervention^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OAE_0000002

has super-classes: planned process^c
has sub-classes: Gene Therapy^c, behavioral intervention^c, combinational intervention^c, drug administration^c, medical procedure^c, placebo medical intervention^c, therapeutic intervention^c, vaccination^c

medical procedure^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OAE_0002807

has super-classes: medical intervention^c
has sub-classes: Surgical Procedure^c

minimum age value specification^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0002556

has super-classes: value specification^c

molecular entity^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CHEBI_23367

has super-classes: object^c; material entity^c; chemical entity^c
has sub-classes: investigational molecular entity^c

n c i t c90468^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C90468

has super-classes: Contact Information^c

n-to-1 design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0500004

has super-classes: cross over design^c

non-random allocation^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000006

has super-classes: Allocation^c

number of participants^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000028

has super-classes: data item^c

object^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000030

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: material entity^c
has sub-classes: molecular entity^c

object aggregate^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000027

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: material entity^c

objective specification^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000005

has super-classes: directive information entity^c
has sub-classes: clinical trial primary purpose specification^c

observation design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0300311

has super-classes: study design^c

Observational Study^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C16084

has super-classes: human subject study^c
has sub-classes: Patient Registry Study^c

occurrent^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000003

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: entity^c
has sub-classes: process^c, process boundary^c, spatiotemporal region^c, temporal region^c
is disjoint with: continuant^c

official title of clinical trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000219

has super-classes: title of clinical trial^c

one-dimensional continuant fiat boundary^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000142

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: continuant fiat boundary^c
is disjoint with: two-dimensional continuant fiat boundary^c, zero-dimensional continuant fiat boundary^c

one-dimensional spatial region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000026

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: spatial region^c
is disjoint with: three-dimensional spatial region^c

one-dimensional temporal region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000038

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: temporal region^c
is disjoint with: zero-dimensional temporal region^c

open blinded design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000114

has super-classes: masking design^c

organismal quality^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PATO_0001995

has super-classes: physical object quality^c
has sub-classes: biological sex^c

organization^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000245

has super-classes: material entity^c
has sub-classes: registry^c

other outcome measure information^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000010

has super-classes: outcome specification^c

outcome measure result^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000039

has super-classes: report^c

outcome measurement datum^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000104

has super-classes: data item^c
has sub-classes: primary outcome measurement datum^c, secondary outcome measurement datum^c

outcome specification^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000051

has super-classes: directive information entity^c
has sub-classes: other outcome measure information^c, primary outcome measure information^c, secondary outcome measure information^c

Pan African clinical trial registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000017

has super-classes: primary registry^c

Pan African clinical trial registry identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000020

has super-classes: Clinical Trial Registry Identifier^c

parallel group design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0500006

has super-classes: study design^c

pathological bodily process^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGMS_0000061

has super-classes: bodily process^c
has sub-classes: adverse event^c

Patient Registry Study^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C129000

has super-classes: Observational Study^c

Personal Attribute^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C19332

has super-classes: information content entity^c
has sub-classes: Age^c

Peruvian clinical trial registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000074

has super-classes: primary registry^c

Peruvian clinical trial registry identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000004

has super-classes: Clinical Trial Registry Identifier^c

phase 1 vaccine trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/VO_0000427

has super-classes: vaccine clinical trial^c

phase 2 vaccine trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/VO_0000428

has super-classes: vaccine clinical trial^c

phase 3 vaccine trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/VO_0000429

has super-classes: vaccine clinical trial^c

phase 4 vaccine trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/VO_0000430

has super-classes: vaccine clinical trial^c

Phase I Trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15600

has super-classes: clinical trial^c

Phase I/II Trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15693

has super-classes: clinical trial^c

Phase II Trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15601

has super-classes: clinical trial^c

Phase II/III Trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15694

has super-classes: clinical trial^c

Phase III Trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15602

has super-classes: clinical trial^c

Phase IV Trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15603

has super-classes: clinical trial^c

phase not applicable^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000043

has super-classes: clinical trial phase^c

phenotypic sex^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PATO_0001894

has super-classes: biological sex^c
has sub-classes: female^c, male^c

physical object quality^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PATO_0001241

Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles.

has super-classes: quality^c
has sub-classes: organismal quality^c

placebo medical intervention^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000103

has super-classes: medical intervention^c

plan specification^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000104

2/3/2009 Comment from OBI review. Action specification not well enough specified. Conditional specification not well enough specified. Question whether all plan specifications have objective specifications. Request that IAO either clarify these or change definitions not to use them

has super-classes: directive information entity^c
has sub-classes: Study Primary Purpose^c, protocol^c, study design^c

planned process^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000011

is equivalent to: realizes^op some concretizes^op some plan specification^c
has super-classes: process^c
has sub-classes: Intervention Type^c, Study Type^c, assay^c, informed consent process^c, investigation^c, medical intervention^c, selection^c

Planned Subject Number^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C49692

has super-classes: data item^c

postal address^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000422

has super-classes: textual entity^c

preclinical finding^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGMS_0000019

has super-classes: data item^c

Prevention Study^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C49657

has super-classes: Study Primary Purpose^c

Primary Outcome Measure^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C98772

has super-classes: data item^c

primary outcome measure information^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000035

has super-classes: outcome specification^c

primary outcome measurement^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000117

has super-classes: clinical trial outcome measurement^c

primary outcome measurement datum^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000105

has super-classes: outcome measurement datum^c

primary registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000073

has super-classes: ClinicalTrial.gov registry^c
has sub-classes: Australian New Zealand clinical trials registry^c, Brazilian clinical trials registry^c, Chinese clinical trial registry^c, Cuban public registry of clinical trials^c, EU clinical trials register^c, German clinical trials register^c, Indian clinical trials registry^c, Iranian registry of clinical trials^c, JAPIC clinical trials registry^c, JMACCT clinical trials registry^c, Korean clinical trials registry^c, Lebanese clinical trials registry^c, Pan African clinical trial registry^c, Peruvian clinical trial registry^c, Sri Lanka clinical trials registry^c, Thai clinical trials registry^c, The Netherlands national trial register^c, UMIN clinical trials registry^c

primary sponsor role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000398

has super-classes: sponsor role^c

principal investigator role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000400

has super-classes: investigator role^c

procedure clinical trIal^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000111

has super-classes: feasibility study^c

process^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000015

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: occurrent^c
has sub-classes: bodily process^c, history^c, planned process^c, process profile^c
is disjoint with: temporal region^c

process boundary^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000035

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: occurrent^c
is disjoint with: temporal region^c

process profile^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000144

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: process^c
is disjoint with: history^c

process quality^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PATO_0001236

See comments of relational quality of a physical entity.

has super-classes: quality^c
has sub-classes: clinical trial phase^c

prospective study design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000047

has super-classes: study design^c

protocol^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000272

has super-classes: plan specification^c
has sub-classes: Study Protocol^c

quality^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000019

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: specifically dependent continuant^c
has sub-classes: physical object quality^c, process quality^c, relational quality^c
is disjoint with: realizable entity^c

Random Allocation^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C142660

has super-classes: Allocation^c

realizable entity^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000017

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: specifically dependent continuant^c
has sub-classes: disposition^c, medical condition^c, role^c, status^c
is disjoint with: quality^c

recruitment status^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000304

has super-classes: status^c

registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/ERO_0001843

has super-classes: organization^c
has sub-classes: clinical trials registry organization^c

relational quality^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000145

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: quality^c

repeated measure design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0500002

has super-classes: intervention design^c
has sub-classes: cross over design^c

report^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000088

has super-classes: document^c
has sub-classes: Clinical Trial Final Report^c, outcome measure result^c, study summary result^c

responsible party role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000102

has super-classes: investigation agent role^c
has sub-classes: sponsor role^c

retrospective study design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000044

has super-classes: study design^c

role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000023

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: realizable entity^c
has sub-classes: contact person role^c, investigation agent role^c, role in human social processes^c
is disjoint with: disposition^c

role in human social processes^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OMRSE_00000024

Previous definition: A role played by an entity in human social processes.

has super-classes: role^c
has sub-classes: legal person role^c

root^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCBITaxon_1

has super-classes: material entity^c
has sub-classes: cellular organisms^c

Screening Study^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71485

has super-classes: Study Primary Purpose^c

secondary identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000001

has super-classes: information content entity^c

Secondary Outcome Measure^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C98781

has super-classes: data item^c

secondary outcome measure information^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000008

has super-classes: outcome specification^c

secondary outcome measurement^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000118

has super-classes: clinical trial outcome measurement^c

secondary outcome measurement datum^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000106

has super-classes: outcome measurement datum^c

secondary sponsor role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000399

In clinicaltrials.gov, the secondary sponsor role can be taken by a project collaborator (Reference: https://prsinfo.clinicaltrials.gov/trainTrainer/WHO-ICMJE-ClinTrialsgov-Cross-Ref.pdf). However, a secondary sponsor may serve as a collaborator role, but a collaborator may not serve as a secondary sponsor role.

has super-classes: sponsor role^c

selection^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0001928

has super-classes: planned process^c
has sub-classes: human subject enrollment^c

selection criterion^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0001755

has super-classes: directive information entity^c
has sub-classes: eligibility criterion^c

sequential design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000115

has super-classes: intervention design^c

sex inclusion criterion^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0002561

has super-classes: inclusion criterion^c

single arm design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000116

has super-classes: intervention design^c

single blinded design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000113

has super-classes: masking design^c

site^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000029

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: immaterial entity^c
is disjoint with: spatial region^c

spatial region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000006

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: immaterial entity^c
has sub-classes: one-dimensional spatial region^c, three-dimensional spatial region^c, two-dimensional spatial region^c, zero-dimensional spatial region^c
is disjoint with: site^c, continuant fiat boundary^c

spatiotemporal region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000011

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: occurrent^c
is disjoint with: temporal region^c

specifically dependent continuant^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000020

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: continuant^c
has sub-classes: quality^c, realizable entity^c
is disjoint with: independent continuant^c, generically dependent continuant^c

Sponsor^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C48355

has super-classes: Homo sapiens^c
has sub-classes: Clinical Study Sponsor^c

sponsor investigator role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000401

has super-classes: investigator role^c

sponsor role^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000243

has super-classes: responsible party role^c
has sub-classes: clinical trial sponsor role^c, primary sponsor role^c, secondary sponsor role^c

Sri Lanka clinical trials registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000075

has super-classes: primary registry^c

status^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000326

has super-classes: realizable entity^c
has sub-classes: human subjects protection review board status^c, recruitment status^c, study status^c

study completion date^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000297

has super-classes: zero-dimensional temporal region^c
has sub-classes: clinical trial primary completion date^c, clinical trial study completion date^c

Study Condition^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C93360

has super-classes: condition^c

study design^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0500000

has super-classes: plan specification^c
has sub-classes: case-control study design^c, factorial design^c, intervention design^c, longitudinal study design^c, masking design^c, observation design^c, parallel group design^c, prospective study design^c, retrospective study design^c

Study Primary Purpose^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C147141

has super-classes: plan specification^c
has sub-classes: Basic Research^c, Diagnosis Study^c, Health Services Research^c, Prevention Study^c, Screening Study^c, Supportive Care Study^c, Treatment Study^c

Study Protocol^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C70817

has super-classes: protocol^c
has sub-classes: Clinical Study Protocol^c

study result^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000032

has super-classes: data item^c

study start date^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000214

has super-classes: zero-dimensional temporal region^c
has sub-classes: clinical trial start date^c

study status^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000327

has super-classes: status^c

study summary result^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000007

has super-classes: report^c

Study Type^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C142175

has super-classes: planned process^c

Supportive Care Study^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71486

has super-classes: Study Primary Purpose^c

Surgical Procedure^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15329

has super-classes: medical procedure^c

telephone number^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OPMI_0000112

has super-classes: contact person information^c

temporal region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000008

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: occurrent^c
has sub-classes: one-dimensional temporal region^c, zero-dimensional temporal region^c
is disjoint with: spatiotemporal region^c, process^c, process boundary^c

Test Facility Country^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C90467

has super-classes: Contact Information^c

Test Facility Name^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C90469

has super-classes: Contact Information^c

textual entity^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000300

has super-classes: information content entity^c
has sub-classes: Contact Information^c, contact affiliation^c, country name^c, postal address^c, title of clinical trial^c

Thai clinical trials registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000050

has super-classes: primary registry^c

Thai clinical trials registry identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000048

has super-classes: Clinical Trial Registry Identifier^c

The Netherlands national trial register^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000012

has super-classes: primary registry^c

The Netherlands national trial register identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000018

has super-classes: Clinical Trial Registry Identifier^c

therapeutic intervention^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OAE_0000094

has super-classes: medical intervention^c

three-dimensional spatial region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000028

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: spatial region^c
is disjoint with: two-dimensional spatial region^c, zero-dimensional spatial region^c, one-dimensional spatial region^c

title of clinical trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000217

has super-classes: textual entity^c
has sub-classes: lay title of clinical trial^c, official title of clinical trial^c

Treatment Study^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C49656

has super-classes: Study Primary Purpose^c

two-dimensional continuant fiat boundary^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000146

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: continuant fiat boundary^c
is disjoint with: one-dimensional continuant fiat boundary^c

two-dimensional spatial region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000009

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: spatial region^c
is disjoint with: three-dimensional spatial region^c

UMIN clinical trials registry^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000037

has super-classes: primary registry^c

UMIN-CTR clinical trial identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000212

has super-classes: Japan clinical trial identifier^c

USA National Clinical Trial identifier^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CTO_0000213

has super-classes: Clinical Trial Registry Identifier^c

vaccination^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/VO_0000002

has super-classes: medical intervention^c

vaccine clinical trial^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/VO_0000596

has super-classes: human subject study^c
has sub-classes: phase 1 vaccine trial^c, phase 2 vaccine trial^c, phase 3 vaccine trial^c, phase 4 vaccine trial^c

value specification^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0001933

has super-classes: information content entity^c
has sub-classes: maximum age value specification^c, minimum age value specification^c

Vertebrata <vertebrates>^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/NCBITaxon_7742

has super-classes: Eukaryota^c
has sub-classes: Mammalia^c

zero-dimensional continuant fiat boundary^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000147

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: continuant fiat boundary^c
is disjoint with: one-dimensional continuant fiat boundary^c

zero-dimensional spatial region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000018

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: spatial region^c
is disjoint with: three-dimensional spatial region^c

zero-dimensional temporal region^c back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000148

is defined by: http://purl.obolibrary.org/obo/bfo.owl

has super-classes: temporal region^c
has sub-classes: date of registration^c, study completion date^c, study start date^c
is disjoint with: one-dimensional temporal region^c

This HTML document was obtained by processing the OWL ontology source code through LODE, Live OWL Documentation Environment, developed by Silvio Peroni.

CTO: Core Ontology of Clinical Trials

Table of Content

Introduction

Classes

action specificationc back to ToC or Class ToC

adverse eventc back to ToC or Class ToC

Agec back to ToC or Class ToC

age group inclusion criterionc back to ToC or Class ToC

age_between_18_and_64c back to ToC or Class ToC

age_between_birth_and_17_yearsc back to ToC or Class ToC

age_older_than_64c back to ToC or Class ToC

Allocationc back to ToC or Class ToC

assayc back to ToC or Class ToC

Australian New Zealand clinical trials registryc back to ToC or Class ToC

Australian New Zealand clinical trials registry identifierc back to ToC or Class ToC

Basic Researchc back to ToC or Class ToC

behavioral interventionc back to ToC or Class ToC

biological sexc back to ToC or Class ToC

Blinded Clinical Studyc back to ToC or Class ToC

bodily processc back to ToC or Class ToC

Brazilian clinical trial registry identifierc back to ToC or Class ToC

Brazilian clinical trials registryc back to ToC or Class ToC

case-control study designc back to ToC or Class ToC

cellular organismsc back to ToC or Class ToC

central contact person of studyc back to ToC or Class ToC

centrally registered identifierc back to ToC or Class ToC

chemical entityc back to ToC or Class ToC

Chinese clinical trail registry identifierc back to ToC or Class ToC

Chinese clinical trial registryc back to ToC or Class ToC

clinical findingc back to ToC or Class ToC

clinical historyc back to ToC or Class ToC

clinical investigatorc back to ToC or Class ToC

Clinical Study Protocolc back to ToC or Class ToC

Clinical Study Sponsorc back to ToC or Class ToC

clinical trialc back to ToC or Class ToC

clinical trial early phase 1c back to ToC or Class ToC

clinical trial enrollmentc back to ToC or Class ToC

Clinical Trial Final Reportc back to ToC or Class ToC

clinical trial outcome measurementc back to ToC or Class ToC

clinical trial participantc back to ToC or Class ToC

clinical trial phasec back to ToC or Class ToC

clinical trial phase 1c back to ToC or Class ToC

clinical trial phase 1/2c back to ToC or Class ToC

clinical trial phase 2c back to ToC or Class ToC

clinical trial phase 2/3c back to ToC or Class ToC

clinical trial phase 3c back to ToC or Class ToC

clinical trial phase 4c back to ToC or Class ToC

clinical trial primary completion datec back to ToC or Class ToC

clinical trial primary purpose specificationc back to ToC or Class ToC

Clinical Trial Registry Identifierc back to ToC or Class ToC

clinical trial sponsor rolec back to ToC or Class ToC

clinical trial start datec back to ToC or Class ToC

clinical trial study completion datec back to ToC or Class ToC

clinical trials registry organizationc back to ToC or Class ToC

ClinicalTrial.gov registryc back to ToC or Class ToC

cohort study designc back to ToC or Class ToC

Collaboratorc back to ToC or Class ToC

combinational interventionc back to ToC or Class ToC

conditionc back to ToC or Class ToC

Condition or Disease under Studyc back to ToC or Class ToC

contact affiliationc back to ToC or Class ToC

contact for public queriesc back to ToC or Class ToC

Contact Informationc back to ToC or Class ToC

contact namec back to ToC or Class ToC

contact of scientific queriesc back to ToC or Class ToC

contact personc back to ToC or Class ToC

contact person informationc back to ToC or Class ToC

contact person rolec back to ToC or Class ToC

continuantc back to ToC or Class ToC

continuant fiat boundaryc back to ToC or Class ToC

country namec back to ToC or Class ToC

cross over designc back to ToC or Class ToC

Cuban public registry of clinical trialsc back to ToC or Class ToC

Cuban public registry of clinical trials identifierc back to ToC or Class ToC

curation status specificationc back to ToC or Class ToC

data about an ontology partc back to ToC or Class ToC

data itemc back to ToC or Class ToC

date of registrationc back to ToC or Class ToC

devicec back to ToC or Class ToC

Device Feasibility Studyc back to ToC or Class ToC

action specification^c back to ToC or Class ToC

adverse event^c back to ToC or Class ToC

Age^c back to ToC or Class ToC

age group inclusion criterion^c back to ToC or Class ToC

age_between_18_and_64^c back to ToC or Class ToC

age_between_birth_and_17_years^c back to ToC or Class ToC

age_older_than_64^c back to ToC or Class ToC

Allocation^c back to ToC or Class ToC

assay^c back to ToC or Class ToC

Australian New Zealand clinical trials registry^c back to ToC or Class ToC

Australian New Zealand clinical trials registry identifier^c back to ToC or Class ToC

Basic Research^c back to ToC or Class ToC

behavioral intervention^c back to ToC or Class ToC

biological sex^c back to ToC or Class ToC

Blinded Clinical Study^c back to ToC or Class ToC

bodily process^c back to ToC or Class ToC

Brazilian clinical trial registry identifier^c back to ToC or Class ToC

Brazilian clinical trials registry^c back to ToC or Class ToC

case-control study design^c back to ToC or Class ToC

cellular organisms^c back to ToC or Class ToC

central contact person of study^c back to ToC or Class ToC

centrally registered identifier^c back to ToC or Class ToC

chemical entity^c back to ToC or Class ToC

Chinese clinical trail registry identifier^c back to ToC or Class ToC

Chinese clinical trial registry^c back to ToC or Class ToC

clinical finding^c back to ToC or Class ToC

clinical history^c back to ToC or Class ToC

clinical investigator^c back to ToC or Class ToC

Clinical Study Protocol^c back to ToC or Class ToC

Clinical Study Sponsor^c back to ToC or Class ToC

clinical trial^c back to ToC or Class ToC

clinical trial early phase 1^c back to ToC or Class ToC

clinical trial enrollment^c back to ToC or Class ToC

Clinical Trial Final Report^c back to ToC or Class ToC

clinical trial outcome measurement^c back to ToC or Class ToC

clinical trial participant^c back to ToC or Class ToC

clinical trial phase^c back to ToC or Class ToC

clinical trial phase 1^c back to ToC or Class ToC

clinical trial phase 1/2^c back to ToC or Class ToC

clinical trial phase 2^c back to ToC or Class ToC

clinical trial phase 2/3^c back to ToC or Class ToC

clinical trial phase 3^c back to ToC or Class ToC

clinical trial phase 4^c back to ToC or Class ToC

clinical trial primary completion date^c back to ToC or Class ToC

clinical trial primary purpose specification^c back to ToC or Class ToC

Clinical Trial Registry Identifier^c back to ToC or Class ToC

clinical trial sponsor role^c back to ToC or Class ToC

clinical trial start date^c back to ToC or Class ToC

clinical trial study completion date^c back to ToC or Class ToC

clinical trials registry organization^c back to ToC or Class ToC

ClinicalTrial.gov registry^c back to ToC or Class ToC

cohort study design^c back to ToC or Class ToC

Collaborator^c back to ToC or Class ToC

combinational intervention^c back to ToC or Class ToC

condition^c back to ToC or Class ToC

Condition or Disease under Study^c back to ToC or Class ToC

contact affiliation^c back to ToC or Class ToC

contact for public queries^c back to ToC or Class ToC

Contact Information^c back to ToC or Class ToC

contact name^c back to ToC or Class ToC

contact of scientific queries^c back to ToC or Class ToC

contact person^c back to ToC or Class ToC

contact person information^c back to ToC or Class ToC

contact person role^c back to ToC or Class ToC

continuant^c back to ToC or Class ToC

continuant fiat boundary^c back to ToC or Class ToC

country name^c back to ToC or Class ToC

cross over design^c back to ToC or Class ToC

Cuban public registry of clinical trials^c back to ToC or Class ToC

Cuban public registry of clinical trials identifier^c back to ToC or Class ToC

curation status specification^c back to ToC or Class ToC

data about an ontology part^c back to ToC or Class ToC

data item^c back to ToC or Class ToC

date of registration^c back to ToC or Class ToC

device^c back to ToC or Class ToC

Device Feasibility Study^c back to ToC or Class ToC

diagnosis^c back to ToC or Class ToC

Diagnosis Study^c back to ToC or Class ToC

directive information entity^c back to ToC or Class ToC

disease^c back to ToC or Class ToC