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Used to describe a location that consists of a number of Regions but where the order is not known. e.g. the oddly named order() keyword in a INSDC file.

The 'both strands position' indicates a region that is best described as being on 'both' strands of a double-stranded sequence, rather than one or the other.

The C-terminus is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

Sometimes a location of a feature is defined by a collection of regions e.g. join() and order() in INSDC records. One should always try to model the semantics more accurately than this, these are fallback options to encode legacy data.

A position that is exactly known.

The position is on the forward (positive, 5' to 3') strand. Shown as a '+' in GFF3 and GTF.

A position that lacks exact data.

This indicates that a feature is between two other positions that are both known exactly and that are next to each other. An example is a restriction enzyme cutting site. The cut is after one position and before the other position (hence, in between).

Use when you have an idea of the range in which you can find the position, but you cannot be sure about the exact position.

As an ordered list of regions (but the list might not be complete).

The position of the starting amino-acid a protein or polypeptide terminated by an amino acid with a free amine group (-NH2). The convention for writing peptide sequences is to put the N-terminus on the left and write the sequence from N- to C-terminus. Instances of this class are often used when the reference sequence is not complete

The position is known to be one of the more detailed positions listed by the location predicate.

Superclass for the general concept of a position on a sequence. The sequence is designated with the reference predicate.

A region describes a length of sequence with a start position and end position that represents a feature on a sequence, e.g. a gene.

The position is on the reverse (complement, 3' to 5') strand of the sequence. Shown as '-' in GTF and GFF3.

Part of the coordinate system denoting on which strand the feature can be found. If you do not yet know which stand the feature is on, you should tag the position with just this class. If you know more you should use one of the subclasses. This means a region described with a '.' in GFF3. A GFF3 unstranded position does not have this type in FALDO -- those are just a 'position'.