###### # # ## ##### ## ##### # # #### # # # # # # # # # # # # # # # # # # # ##### # # #### # # ###### # ###### # # # # # # # # # # # # # # # # # # ###### # # # # # ##### #### #### # Plugin version 1.3-SNAPSHOT - https://github.com/dbpedia/databus-maven-plugin @prefix databus: . @prefix dataid-mt: . @prefix dct: . @prefix dataid: . @prefix rdf: . @prefix dataid-cv: . @prefix xsd: . @prefix rdfs: . @prefix dcat: . @prefix prov: . @prefix dataid-debug: . dataid-mt:UNKNOWN a dataid-mt:MediaType ; dataid:mimetype "UNKNOWN" . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "parsed" ; dataid:file ; dataid:formatExtension "owl" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "\n\n \n \n \n \n \n \n \n 1.4" ; dataid:sha256sum "c8c19dbed5cef0af1899a92d804c9893e47157a9b8311c179f34970ebe10cf91" ; dataid:signature "R+QZkg/gsBCw38xKajtvMQgvUCsMiDlf/sCR10LQ0b/gf6l1v+2Iuxqrtq2ctUuHBU+Duq3w1wBYE9ElbaKJQQ9sNcrRggLeTYj3WWO1M7LZMM8unD3LRU0VUniKbHOc2Z9my0xoTc0gOCimC6IzIjX6Tjn82QIjuPxwJnBM9h3WalQ8ycEbBddt8iVYy95hqXdHieuI4gmCltWLuIBxuersDcWLxWWbz4T40gWjR12D72mIBMF4Hnjb+B7hKfcht8L35qvhjm2asTn2z9DIheaQ1BYqDKwWw1dMqxpPhaN+uFQfdpCuWfBhnXPN3vAGwjqrw6a0sRNQzqkR1rJoqg==" ; dataid-cv:type "parsed" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:14:42Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "444884211"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationRDFXML . dataid-cv:tag rdfs:subPropertyOf dataid:contentVariant . dataid-mt:ApplicationJson a dataid-mt:MediaType ; dataid:mimetype "application/json" . dataid-mt:TextPlain a dataid-mt:MediaType ; dataid:mimetype "text/plain" . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "FULL" , "pelletInfo" ; dataid:file ; dataid:formatExtension "txt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "WARNING: An illegal reflective access operation has occurred\nWARNING: Illegal reflective access by com.google.inject.internal.cglib.core.$ReflectUtils$2 (file:/usr/lib/pellet/cli/target/pelletcli/lib/guice-4.0.jar) to method java.lang.ClassLoader.defineClass(java.lang.String,byte[],int,int,java.security.ProtectionDomain)\nWARNING: Please consider reporting this to the maintainers of com.google.inject.internal.cglib.core.$ReflectUtils$2\nWARNING: Use --illegal-access=warn to enable warnings of further illegal reflective access operations\nWARNING: All illegal access operations will be denied in a future release\n[main] WARN org.semanticweb.owlapi.util.SAXParsers - http://www.oracle.com/xml/jaxp/properties/entityExpansionLimit not supported by parser type org.apache.xerces.jaxp.SAXParserImpl\n[main] WARN org.semanticweb.owlapi.util.SAXParsers - entityExpansionLimit not supported by parser type org.apache.xerces.jaxp.SAXParserImpl\n[main] WARN org.semanticweb.owlapi.util.SAXParsers - http://www.oracle.com/xml/jaxp/properties/entityExpansionLimit not supported by parser type org.apache.xerces.jaxp.SAXParserImpl\n[main] WARN org.semanticweb.owlapi.util.SAXParsers - entityExpansionLimit not supported by parser type org.apache.xerces.jaxp.SAXParserImpl\n[main] ERROR org.semanticweb.owlapi.rdf.rdfxml.parser.OWLRDFConsumer - Entity not properly recognized, missing triples in input? http://org.semanticweb.owlapi/error#Error1 for type Class" ; dataid:sha256sum "f020b0280421c62a5055bdd3c2cb03c750b3088ebf5a93e5267c95140516c947" ; dataid:signature "HjODYKXS2A+bspiXhDnB/IpWPLlTKwwuY9kgUDt7xVRSQuYy7z0OH0QpF3oTstMDxveyKU8HZIau6LZPBWP4QkbDZx6R5brxaLiVsIZTxFqvaCCM/Pv6k5okLcCEephG7nmBRl4iPCLYZcBwt8PiJtvTM3U3nGzxEIir5VJEPcTWLlZ3Hln3bGfRquuTYkb8REdk3Pt9Q71OW3ZODO7MLshN5G1nS604JDUlWSAqlC9TgxrIXbm27WPAwaYLq5vDco9ongpF/f5VamZfL2pTFvfYhB+pcB9oa0T7Yo2m8mhsk/hJ079fHYfiANjXkU1ZQr3Abvp9imWJQFQtjJxlQA==" ; dataid-cv:imports "FULL" ; dataid-cv:type "pelletInfo" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:40:11Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "111447"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:TextPlain . dataid-mt:TextTurtle a dataid-mt:MediaType ; dataid:mimetype "text/turtle" . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "generatedDocu" ; dataid:file ; dataid:formatExtension "" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "LODE error

LODE error

Reason: Server returned HTTP response code: 400 for URL: https://objects.githubusercontent.com/github-production-release-asset-2e65be/93400523/68b0934a-8ad8-4d24-b3d6-fc96ce7a6917

\n" ; dataid:sha256sum "1d3fe7b7d915e246b015ed05270566ec3c129c228298f6c20331a8a88816bab8" ; dataid:signature "ohdqNw0FhCZ31ilTAMk+p7Q07AekIXWLpk1IbPkCr1L1nwzV6NFfwGiR/WTvycnMSA3r6mNLKtuuzuZigM8eA1coJQIRYNGq19VxvmQjUPYbDpOSuJWPaszDpVskMg94/dWwwNX9NE2eJrfCHcx+jz+uTw8BHCaOrbwD46+XVbEKlp+/pq+mkKQVWzLwl53i/cqdmWVQGY+5Sj/79S/q6/PVZzcrXRqV9SVmhr2MAfe8Qt/hMDm6hbII4O2OUv2+4MUY9jlEHYge8ar1wuRSq4KIr6RRTElsB42KuX/L7erca1L4ZwrPfaYPVNSd2olWt9SvH4JqSuAQwlf33GCyWw==" ; dataid-cv:type "generatedDocu" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:42:34Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "288"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:UNKNOWN . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "old" , "diff" ; dataid:file ; dataid:formatExtension "nt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview " \"Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime\"@en .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nMale germ cells are specialized cells that give rise to the male gametes and are therefore crucial for sexual reproduction in males. Through a complex process called spermatogenesis in the testes male germ cells undergo several stages of development, each with distinctive morphological and physiological characteristics, eventually differentiating into mature spermatozoa (sperm). \\nMale germ cells are responsible for transferring genetic material from male to offspring as part of sexual reproduction. In the initial stage of their life cycle, they exist as spermatogonial stem cells, which multiply by mitotic division to self-renew and to produce daughter cells. The daughter cells then undergo meiotic division, a process that reduces the number of chromosomes in each cell by half, from diploid to haploid \\u2013 the formation of spermatids. This is critical for maintaining genetic stability from generation to generation, as it ensures that when an egg and sperm cell unite during fertilization, the resulting offspring will have the correct number of chromosomes. The final phase of spermatogenesis is called spermiogenesis, during which spermatozoa - mature and motile sperm cells \\u2013 are produced from round spermatids. \\nThe matured male germ cells or sperm cells are highly specialized, having a streamlined shape designed for efficient movement towards the female egg. A sperm cell is divided into three main parts, namely the head, midpiece, and tail. The head contains the genetic material, the midpiece contains mitochondria that provide energy, and the tail, termed as the flagellum, propels the sperm cell forward. Each of these parts play significant roles in fertilization.\" .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nSperm cells, also known as spermatozoa or male gametes, are highly specialized cells that are pivotal for sexual reproduction in animals. Produced in the male reproductive organs, specifically the testes, sperm cells play an important role in the process of fertilization, where they fuse with a female gamete or egg cell (ovum) to form a zygote, which marks the beginning of a new organism.\\nSperm cells hold several unique traits that set them apart from other body cells. Structurally, a sperm cell possesses two main structures: the head, containing the nucleus carrying the paternal genetic information, and the flagellum, which generates energy and grants the sperm cell mobility\\nThe process of fertilization occurs when one sperm cell successfully penetrates the egg, delivering its genetic information, and ultimately leading to the formation of a new individual combining both paternal and maternal genetic materials. Notably, while hundreds of millions of sperm cells may be released during ejaculation, only one has the opportunity to successfully fertilize the egg, underscoring the highly competitive nature of this biological process.\" .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nKupffer cells are tissue-resident macrophages located in the liver. They are an integral part of the mononuclear phagocyte system and are responsible for the phagocytosis of dead or dying cells, microbes, and other foreign substances. Kupffer cells account for approximately 80-90% of tissue-resident macrophages in the body. They are found within the lumen of liver sinusoids and interface with microbial populations and products.\\nThe primary role of Kupffer cells is to maintain homeostasis in the liver. They continuously filter and cleanse the blood that flows through the liver, removing pathogens, endotoxins, particulate matter, aged and dysfunctional red blood cells, and miscellaneous waste products. These cells also play an important role in maintaining iron homeostasis. During the process of phagocytosis, Kupffer cells recycle iron from degraded red blood cells, which is then utilized in the formation of new erythrocytes.\\nKupffer cells also play key roles in various immune responses and inflammatory processes. They secrete various types of cytokines and chemokines, which contribute to the activation and mobilization of other immune cells. They can also produce reactive oxygen species and nitric oxide, which have microbicidal actions. Although their activity is essential for host defense, excessive or prolonged activation of Kupffer cells may contribute to hepatic injury, inflammation, and fibrosis.\" .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nOsteoclasts, derived from the monocyte/macrophage lineage, play a crucial role in bone remodeling through bone resorption. They are distinguished from other cells by their large size and their unique ability to secrete enzymes and acids that dissolve the calcium phosphate in bone. The formation of osteoclasts is influenced by two primary factors: macrophage colony-stimulating factor (M-CSF) and the ligand-activated receptor (RANKL) of nuclear factor kappa B (NF-\\u03BAB).\\nOsteoclasts also collaborate with osteoblasts, responsible for new bone formation, to maintain bone health and adapt bone structure. Their coordinated actions allow continuous remodeling while preserving overall bone strength and integrity. Imbalances in osteoclast activity can lead to pathological conditions. For example, excessive activity may contribute to diseases like osteoporosis, periprosthetic osteolysis, bone tumors, and Paget's disease. Other the other hand, osteoclast deficiency ca result in conditions like osteopetrosis.\" .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nGlial cells, also known as neuroglia or simply glia, are non-neuronal cells in the central and peripheral nervous systems that provide support and protection for neurons. They constitute approximately half of the total cells in the human brain and more than half in other parts of the nervous system. Glial cells perform several key functions including, but not limited to, maintaining homeostasis, forming the myelin sheath around the neuron axons, and providing support and nutrition to neurons.\\nThese different functions are performed by various glial cell types, including astrocytes, oligodendrocytes, microglia and other specialized types. Astrocytes, for example, are the most abundant glial cells and provide metabolic and nutrient support to neurons, help regulate the extracellular ion and neurotransmitter levels, and play a role in the formation and maintenance of the blood-brain barrier, contributing to the overall homeostasis and functioning of the nervous system. Additionally, astrocytes are involved in synaptic communication and participate in processes such as synaptogenesis and synaptic pruning.\\nOligodendrocytes in the central nervous system function to insulate neurons by producing a fatty substance known as myelin. The myelin sheath enhances the speed and efficiency of nerve impulse conduction along the axons. \\nMicroglia, the immune cells of the central nervous system, protect neurons from pathogens and clear away dead neurons through phagocytosis, a process also known as cellular eating. They also contribute to the regulation of inflammation in response to signals of tissue damage or infection in the central nervous system by releasing cytokines and other signaling molecules that modulate the immune response.\\nDespite their overarching function in the support and protection of neurons, glial cells have also been shown to play significant roles in the pathophysiology of many psychiatric and neurodegenerative diseases, such as Alzheimer\\u2019s, Parkinson\\u2019s Disease and multiple sclerosis.\" .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nMicroglial cells, sometimes referred to as microglia, are a type of glial cell that primarily exist within the central nervous system (CNS), notably in the brain and the spinal cord. Classified among the resident immune cells, microglial cells represent about 10% of all cells found within the CNS. These cells are derived from progenitor cells in the yolk sac, which differentiates them from other types of glial cells (such as astrocytes and oligodendrocytes) that are derived from neuroectodermal cell lineages. \\nThe primary role of microglial cells is to act as the first and main active form of immune defense in the CNS. They express a vast repertoire of pattern recognition receptors, which allow them to sense and eliminate microbes invading the CNS parenchyma. They represent one of the macrophage populations of the CNS and are responsible for phagocytosis (engulfing and destroying cellular waste or pathogens) in the neural environment. \\nMicroglial cells are particularly responsive to pathogens and injuries and change their morphology in reaction to inflammation or insult: In the normal state they are characterized by a ramified shape with small processes; in response to stimuli, some microglia mature and change to an amoeboid shape. \\nBeyond their macrophagic activity, they also perform synaptic pruning during brain development, eliminate unnecessarily produced neurons, and facilitate tissue regeneration and repair. they play integral roles in regulating neural development and supporting cell survival and are important for maintaining tissue homeostasis. \\nWhile their protective role generally benefits the brain, their over-activation can occasionally lead to neuro-inflammatory diseases, underlining the importance of balanced microglial cell functions. They have been extensively studied for their association with neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis.\" .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nMelanocytes are specialized cells prevalently found in the skin, but also present in the hair follicles, eyes, inner ear, bones, heart, and brain. Their primary function is the synthesis of melanin, a pigment responsible for coloration of skin, hair, and eyes. The presence and distribution of this pigment play a crucial role in the body's defense mechanism against harmful ultraviolet radiation.\\nIn addition to melanin production, melanocytes also engage in a variety of other biological functions. They play a fundamental role in the immune response, owing to their ability to present antigens to T cells. Furthermore, they contribute to the maintenance of the skin's homeostasis by regulating processes such as extracellular matrix remodeling and cytokine production. A balance in melanocyte function is pivotal, as dysfunctions often result in dermatological disorders. For instance, the loss of melanocytes or reduction in their function may lead to hypopigmentation conditions such as vitiligo, whereas an abnormal increase could result in hyperpigmentation disorders or melanoma, a dangerous type of skin cancer.\" .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nGoblet cells are specialized, simple columnar, secretory epithelial cells that are mostly found in the respiratory and intestinal tracts. The term \\\"goblet\\\" refers to their shape, which resembles a flask or goblet, specially at their apical end which is swollen due to the accumulation of secretory granules. \\nThe primary function of goblet cells is to to protect and lubricate the underlying tissues by secreting large quantities of mucin, a complex glycoprotein, which forms mucus when hydrated. In the respiratory tract, the mucus secreted by these cells traps dust, bacteria, viruses, and other potentially harmful particles in the inhaled air, preventing them from reaching the delicate tissues of the lungs. In the intestines, the goblet cells secrete mucus that acts as a protective barrier shielding the intestinal epithelium from dietary antigens, pathogens and prevents the intestinal epithelium from being eroded by the actions of the digestive enzymes and the abrasive action of passing food material.\\nGoblet cells are capable of rapidly altering their secretory output in response to stimuli. For example, irritants like smoke or dust can trigger an increased rate of mucus production, as the body attempts to flush out the harmful particles. Conversely, in conditions such as chronic bronchitis and cystic fibrosis, overactive goblet cells can create a thick accumulation of mucus that obstructs the airways and fosters bacterial growth. Lastly, goblet cells are not static, rather, they undergo a dynamic process known as goblet cell metaplasia-differentiation, wherein non-goblet cells in response to chronic injury or inflammation, can differentiate into goblet cells leading to an accumulation of these cells in the tissue, known as goblet cell hyperplasia.\" .\n \"This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.\\n\\nChromaffin cells, also known as pheochromocytes, are neuroendocrine cells that are typically located in the adrenal medulla, the innermost part of the adrenal gland, which is situated on top of each kidney. Chromaffin cells are also found in small clusters, known as paraganglia, in various locations throughout the body, including the sympathetic nervous system. They derive their name from their ability to stain a brownish-black color upon exposure to chromic salts, a feature made possible due to their high content of granules rich in catecholamines and catecholamine-related neurotransmitters.\\nThe primary function of chromaffin cells is the synthesis and release of catecholamines, specifically epinephrine (adrenaline) and norepinephrine (noradrenaline). These neurotransmitters are vital stress hormones that, when released by the adrenal chromaffing cells into the bloodstream, prepare the body for the 'fight or flight' response. This response can enhance the body's performance in a dangerous situation by increasing heart rate, elevating blood sugar, and increasing blood flow to the muscles. The chromaffin cells in paraganglia are responsible for the local release of catecholamines and play a role in regulating blood pressure and other autonomic functions.\\nIn addition to their role in stress response, chromaffin cells also contribute to the body's immune response. They secrete several peptides including antimicrobial peptides, and the discovery of LPS and cytokine receptors on chromaffin cells suggests that the adrenal medulla may participate in some aspects of the immune response.\" ." ; dataid:sha256sum "89db3ff11306927c38d571d6ef87d774eadea7f4e6e01305b4643c820aa98d83" ; dataid:signature "DUsemPB8vUh6EWdWqy6YWSPnBJSAU5dCx+ePdy+Kzu8bnKLTT9I1UDNtiHK5LaIIQNqAHkbx/qdnWNsHShjFNTgk57z/IquJ8K5szVijM9FeVLhLTqz4cfAqpe0bt5twOdzgi+OzRdinOkXznCAWe2dO3hoNfj7fAlZ2zxMfNISSMpB0+0xoWz9nqYTjjAHAUxzDe2XlWf4YHeL3g2buBCoUwtadG0tQCpl0vsJPtdDM9LODucu5LbjVX9BrJRm201eTw4b2LXq2D1C38gpyL7dCKCHJcAM7ejAkZ49p+OV4SEogTT+PizDzRZz6MzSSTKNzyiG7DULJZsUyMAmtEg==" ; dataid-cv:triples "old" ; dataid-cv:type "diff" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:11:36Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "160153250"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationNTriples . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "profile" ; dataid:file ; dataid:formatExtension "txt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "WARNING: An illegal reflective access operation has occurred\nWARNING: Illegal reflective access by com.google.inject.internal.cglib.core.$ReflectUtils$1 (file:/usr/local/src/webapp/archivo/archivo/helpingBinaries/profilechecker-1.1.0.jar) to method java.lang.ClassLoader.defineClass(java.lang.String,byte[],int,int,java.security.ProtectionDomain)\nWARNING: Please consider reporting this to the maintainers of com.google.inject.internal.cglib.core.$ReflectUtils$1\nWARNING: Use --illegal-access=warn to enable warnings of further illegal reflective access operations\nWARNING: All illegal access operations will be denied in a future release\n[main] ERROR org.semanticweb.owlapi.rdf.rdfxml.parser.OWLRDFConsumer - Entity not properly recognized, missing triples in input? http://org.semanticweb.owlapi/error#Error1 for type Class\n[main] ERROR org.semanticweb.owlapi.rdf.rdfxml.parser.OWLRDFConsumer - Entity not properly recognized, missing triples in input? http://org.semanticweb.owlapi/error#Error2 for type Class\n[main] ERROR org.semanticweb.owlapi.rdf.rdfxml.parser.OWLRDFConsumer - Entity not properly recognized, missing triples in input? http://org.semanticweb.owlapi/error#Error3 for type Class\nException in thread \"main\" java.lang.StackOverflowError\n\tat org.semanticweb.owlapi.rdf.rdfxml.parser.OWLRDFConsumer.lambda$translateAnnotations$24(OWLRDFConsumer.java:1631)" ; dataid:sha256sum "bad7fcf7a00ecf3fc1adc0423943feff63841cda87b6db82665bfe7f1d8b9f2e" ; dataid:signature "gQv07u4W1fX0Jii+5eNFFz8O5b3rIo05XRDuiWMIMP8uVCVXfH+rDfq761Q3AZE27NxkK1RKltpiLQ6sa84bzvrYAJvgxi+7Nf+vllm7zWvgh1QimW2fKwxxMiu1wpEEd3/NHgBOlVLRWvtPQQdArDlW0U/dxk0JO9dDbPDM+hxh5INRMMkTYonn0m8cd+Z5SJa5SJhRxCPTAZtQW0Fen7GgBxF6tDsSqeNdzZY5BZrXNfFtj9sBwJxoYmjGPcWyu8XeOvds2CBxODjsaAIVWSKiuUTBs+UhArVuY5ycDISe9euAWwsU6ubnfOBLT8l6F48/utuaZn8sTvC3NaVEPw==" ; dataid-cv:type "profile" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:42:32Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "97878"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:TextPlain . dataid-cv:imports rdfs:subPropertyOf dataid:contentVariant . a dataid:Group . dataid-cv:validates rdfs:subPropertyOf dataid:contentVariant . a dataid:Version . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "goodLicense" , "shaclReport" ; dataid:file ; dataid:formatExtension "ttl" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "@prefix dct: .\n@prefix sh: .\n@prefix xsd: .\n\n[] a sh:ValidationReport ;\n sh:conforms false ;\n sh:result [ a sh:ValidationResult ;\n sh:focusNode ;\n sh:resultMessage \"dct:license statement is not an IRI\"@en ;\n sh:resultPath dct:license ;" ; dataid:sha256sum "33eb58ddf5f8f1062885de8b9d7a2c5a36ab1ab039e4f9407095759e29f3aa41" ; dataid:signature "MejMSn1m49oonUCDHfj8dB7VxypjgZzYznGm+fE/QStwuvGjDCr+6wUrc1zRupMWw7/e+GoxqkTNacLumvWntg+O4ZCrsK7UnUO6kAOE+PbNa6NmjvLWQaq0viETU4WhJeyVyf2xW/QZ1XEV1hOsUD2Z39oeufmaTQcnyet4rNZcwNrEGkMGFiImhgcvIq8DIBfk9fpzH5KX6gt7izEZu3d4I/aQR3yy17ub8H1BwWySTTblI0XgO2t4jTRqoQmN60bYDLRlJC1aX0oGOIPKrShbXn5Y5g1dX2smpcEwjR5M3vP4a3z6M9CQ17Ko36nMUJPipl5f3zykF26FS4eVtA==" ; dataid-cv:type "shaclReport" ; dataid-cv:validates "goodLicense" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:36:42Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "717"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationNTriples . dataid-cv:axioms rdfs:subPropertyOf dataid:contentVariant . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "diff" , "old" ; dataid:file ; dataid:formatExtension "" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "Exception in thread \"main\" java.lang.StackOverflowError\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.getAnnotatedSourceAnnotationMainNodes(OWLRDFConsumer.java:1140)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1943)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)" ; dataid:sha256sum "b79aeef6e3c6856898888c7bd5a1602edc220586d8eaad8a83206760a137c8a0" ; dataid:signature "lpGDQcq6TC4SevBVVhNVN7BAZTWnRH1HsxnjWYvlWDWYG/+uL6Ar8i57hqUZ6F1eYXN90PnOroxuyxYBb/II9xKbmMgbgDxOpiywrVYXLobclmJ8nW+kBy41kgz30BBf14lCUQRsfZrRNCcihgfs0+Qd8KNgwxCRJ2CtkOQwqAa4NTm0fINSiimxMtpwTyFl9W8HHWf18Cj73qme1cFyxXk76lWa15HAbP03M4/7qrh5UvvPzh385Ps+IcmcPYy08xm+gfNDryxuDfahoLzMhr7kqA6SOalaL7w349CfzUIgTg65n1zlMuqqa9RxQ0blcqyq25ipoEjayFAo36279w==" ; dataid-cv:axioms "old" ; dataid-cv:type "diff" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:11:35Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "99402"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:UNKNOWN . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "shaclReport" , "lodeMetadata" ; dataid:file ; dataid:formatExtension "ttl" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "@prefix dc: .\n@prefix owl: .\n@prefix rdfs: .\n@prefix sh: .\n@prefix xsd: .\n\n[] a sh:ValidationReport ;\n sh:conforms false ;\n sh:result [ a sh:ValidationResult ;\n sh:focusNode ;" ; dataid:sha256sum "cea16905b18d91e1b4d6a31b42c3a6dc8a814d93010e2ffe9e0d339dedafc2a6" ; dataid:signature "RtvZuGuIOe1kZkjrGU4FKCJO78HVT5EMXeqgXZjJW6ogUhX64VBvehoH8QEydnsqgVD36W7uEfn9gUYOnVUIy4BYzHqVtKIpLKKjWV1fAlXPA7BhkxHvXNn5fg7zc086HK8RX37879CRXmTZhJD84+rJRoovzOuFIAYmGSONOaDxKjZj+P9Fpf1utetwwTxPyp+T/CRvGPSlGlrDM3egz/ZXgSXetDJFOussv/Xwr99dbD6HT/AgcUceLyA+ViBivxCxbw8gCHFP9zuKTOUbadC+098CkumqjgLSITzaMDy3tWwCaWJBY09+yYhgebn9YRSajw18ehLcTTtZm05k/w==" ; dataid-cv:type "shaclReport" ; dataid-cv:validates "lodeMetadata" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:34:19Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "55845702"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationNTriples . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "diff" , "new" ; dataid:file ; dataid:formatExtension "" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "Exception in thread \"main\" java.lang.StackOverflowError\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.getAnnotatedSourceAnnotationMainNodes(OWLRDFConsumer.java:1140)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1943)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)\n\tat org.coode.owlapi.rdfxml.parser.OWLRDFConsumer.translateAnnotations(OWLRDFConsumer.java:1946)" ; dataid:sha256sum "b79aeef6e3c6856898888c7bd5a1602edc220586d8eaad8a83206760a137c8a0" ; dataid:signature "lpGDQcq6TC4SevBVVhNVN7BAZTWnRH1HsxnjWYvlWDWYG/+uL6Ar8i57hqUZ6F1eYXN90PnOroxuyxYBb/II9xKbmMgbgDxOpiywrVYXLobclmJ8nW+kBy41kgz30BBf14lCUQRsfZrRNCcihgfs0+Qd8KNgwxCRJ2CtkOQwqAa4NTm0fINSiimxMtpwTyFl9W8HHWf18Cj73qme1cFyxXk76lWa15HAbP03M4/7qrh5UvvPzh385Ps+IcmcPYy08xm+gfNDryxuDfahoLzMhr7kqA6SOalaL7w349CfzUIgTg65n1zlMuqqa9RxQ0blcqyq25ipoEjayFAo36279w==" ; dataid-cv:axioms "new" ; dataid-cv:type "diff" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:11:35Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "99402"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:UNKNOWN . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "pelletConsistency" , "NONE" ; dataid:file ; dataid:formatExtension "txt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "There are 1 input files:\n/usr/local/archivo-data/ebi.ac.uk/efo--efo--owl/2025.02.17-220805/efo--efo--owl_type=parsed.ttl\nStart loading\nFeb 17, 2025 10:38:03 PM org.mindswap.pellet.jena.graph.loader.DefaultGraphLoader addUnsupportedFeature\nWARNING: Unsupported axiom: Invalid list structure: List edfbb1180038de55fa9f1e87d5dde809 does not have a rdf:first property. Ignoring rest of the list.\nFeb 17, 2025 10:38:04 PM org.mindswap.pellet.jena.graph.loader.DefaultGraphLoader addUnsupportedFeature\nWARNING: Unsupported axiom: Invalid list structure: List 88885b1d1d7e459c3138350aa4215092 does not have a rdf:first property. Ignoring rest of the list.\nFeb 17, 2025 10:38:04 PM org.mindswap.pellet.jena.graph.loader.DefaultGraphLoader addUnsupportedFeature\nWARNING: Unsupported axiom: Ignoring equivalentClass axiom because the object is not a class http://www.ebi.ac.uk/efo/EFO_0005220 owl:equivalentClass bnode(01d31a8472975f8bf374a239dfb13fa2)\nFeb 17, 2025 10:38:07 PM org.mindswap.pellet.jena.graph.loader.DefaultGraphLoader addUnsupportedFeature" ; dataid:sha256sum "0e5bfa9b1927256b430b1dde9a928e71ae763c86a9808fc1d05ab88272439110" ; dataid:signature "W0cSYVIj0zxU1+S67YWLoztH3QfMxSqkKiPQ67xENm/wwPHT27wzEGWHetQ+a6dmjDLH0351ZHLzudYH3XnQdn2Kw8bzLSDA/XiYVSXADBo3EYZ+BA/JmxVLiJzVEoLPIYnIGw9NJ91xz4YOSvxaOlhU7wsitsyODdPPW5XVkPZyN1Zz2jC+85vtikYfbIDkxFp59OtwE8+rgYuZOi7dERCbj3fWgjRS5hTgQ4bpDlD1LZA3Sj5Qb+In7ueZIkAnetQ/iuX3GUCoRcl5WcgxhPPdhKTpPnqngxzggE5dgXOuqBr6qBfXsKPkExdX+lgZjCBlrUQ6+Xm+6iQThj0TvA==" ; dataid-cv:imports "NONE" ; dataid-cv:type "pelletConsistency" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:38:34Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "7140"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:TextPlain . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "parsed" ; dataid:file ; dataid:formatExtension "nt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview " .\n .\n \"1.4\" .\n \"Catherine Leroy\" .\n \"Dani Welter\" .\n \"Drashtti Vasant\" .\n \"Ele Holloway\" .\n \"Eleanor Williams\" .\n \"Emma Kate Hastings\" .\n \"Gautier Koscielny\" ." ; dataid:sha256sum "c2eb056614470d0b6c0ebbca630cb8560c3fe55b37471e3b7c3a68db2c69fc86" ; dataid:signature "gonpWeZ+As8Dv9xzDwqRi9EOel5cTtJEwC0js59tAzsDrHpCkqW8oYjR0AKG0MsJGUGGZ/GLKXxHgrrCwD6t9EeVPEUjWvGGoIpEZBIlY/dVTfpFvYL4IavXaH3T3xxjxrf71byO1zQ3GqlL7yAq6WOaK+Rus79jWE1rCp7V+mvsPRHr9A/SGZUBf0eGhYeDPs5GrdUroP7KV+lyrsUvEMRzF4JahcMxptTqF0tf4TwRxwoDjVOEfDV6pO7p/uh1SZ2WGLbAAnqry+ua2E37l8GSNWJWrgq+MY2zaupfC9RK1iBvgY22yPmQy1oes1ABSP7VDAHeUw4n8fJ0X/nUNg==" ; dataid-cv:type "parsed" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:12:06Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "336369181"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationNTriples . dataid-cv:triples rdfs:subPropertyOf dataid:contentVariant . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "parsed" ; dataid:file ; dataid:formatExtension "ttl" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "@prefix rdf: .\n@prefix : .\n@prefix dc: .\n@prefix EFO: .\n@prefix efo: .\n@prefix obo: .\n@prefix owl: .\n@prefix xml: .\n@prefix xsd: .\n@prefix core: ." ; dataid:sha256sum "2528feff7ae4d2f16d94f1eb2d6ca5ab4e42881936645e333dfb85848ce58f3d" ; dataid:signature "iZPxADjmDJVRL3pDiFPdFM49rdXsxBdc3ThGRuaw+VgzWy7RpflFS+EEcpMrx/FGASW/oOfmXiBnNnvv0cBx0x/8ZrP1Twcix9EN1I9atd9vVjkWyajixh2TEgcVkaxDopyuc+swGG101KySZ919BZhXPqj3N2DY85564QSd4wxb5Xl9gGlItC7S2rbPSArwFMq+JFNvRgu6eRnF+N1ac1plU3FEu29kjh1xdYCJxmQnDeSDnjq+Zx1pC7IJE3QdGoCzXi2JKqzvxB/jI5R2x09wmvUpEpmS0bryCnIpSBbyAfapCrFyHiV6dSLr8ONKrcfngkmQWImUmKXJlXx48g==" ; dataid-cv:type "parsed" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:13:05Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "123200232"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:TextTurtle . dataid-mt:ApplicationNTriples a dataid-mt:MediaType ; dataid:mimetype "application/n-triples" . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "pelletConsistency" , "FULL" ; dataid:file ; dataid:formatExtension "txt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "There are 1 input files:\n/usr/local/archivo-data/ebi.ac.uk/efo--efo--owl/2025.02.17-220805/efo--efo--owl_type=parsed.ttl\nStart loading\nFeb 17, 2025 10:37:06 PM org.mindswap.pellet.jena.graph.loader.DefaultGraphLoader addUnsupportedFeature\nWARNING: Unsupported axiom: Invalid list structure: List f2574836ee62f69f51a60096241801a1 does not have a rdf:first property. Ignoring rest of the list.\nFeb 17, 2025 10:37:07 PM org.mindswap.pellet.jena.graph.loader.DefaultGraphLoader addUnsupportedFeature\nWARNING: Unsupported axiom: Invalid list structure: List 67ca014d31b7d163436a86b5214f80a1 does not have a rdf:first property. Ignoring rest of the list.\nFeb 17, 2025 10:37:08 PM org.mindswap.pellet.jena.graph.loader.DefaultGraphLoader addUnsupportedFeature\nWARNING: Unsupported axiom: Ignoring equivalentClass axiom because the object is not a class http://www.ebi.ac.uk/efo/EFO_0005220 owl:equivalentClass bnode(bbb073ba509ad7592195d05a6257df89)\nFeb 17, 2025 10:37:08 PM org.mindswap.pellet.jena.graph.loader.DefaultGraphLoader addUnsupportedFeature" ; dataid:sha256sum "9bacbf879722f3ed3701b3259444f5a0b6940cfd7454123ca17c199cf2068d73" ; dataid:signature "fvo32Gnz+tQSymq+8JC7ysYHGBZiByyzPegwLpxkBhbmFZEprcODqm7lXyiCbqkW+rMibOSA4xYUGm73CLFV6QwfkDMbgektSPvGsjgYkwuhzfZQnUYYWU10ZLDX69kpO1vOvV/yR7OcHmxNavQW2qNV1LqeZsZ2XlE9EgWUVeTzBfs8KU/TFkeK3y4vn3xPXeCrE5SjcPMO56kU5M0EV/iM1a4CQhi/gWjPcK1FPsv5uDRJK9PmkTpRVy7JzQQbdi3vutye1l/uO7/u6xBX3DnxbtxNth2gqPjzAJABCLjGZ0xOIMP9kmC5K+mT/dPPgayAgIv9nOj9+8cS70mvJA==" ; dataid-cv:imports "FULL" ; dataid-cv:type "pelletConsistency" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:38:34Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "7140"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:TextPlain . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "orig" ; dataid:file ; dataid:formatExtension "owl" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "\n ; dct:modified "2025-02-17T22:08:42Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "232113686"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationRDFXML . dataid-mt:ApplicationRDFXML a dataid-mt:MediaType ; dataid:mimetype "application/rdf+xml" . dataid:contentVariant a . a dataid:Dataset ; rdfs:comment "Archivo Ontology Snapshot for http://www.ebi.ac.uk/efo/efo.owl"@en ; rdfs:label "http://www.ebi.ac.uk/efo/efo.owl"@en ; dataid:account databus:ontologies ; dataid:artifact ; dataid:associatedAgent ; dataid:group ; dataid:groupdocu "## All DBpedia Archivo ontologies from ebi.ac.uk domain\n\nEach artifact in this group deals as the archive for snapshots of one ontology of the [DBpedia Archivo](https://databus.dbpedia.org/ontologies) - A Web-Scale Interface for Ontology Archiving under Consumer-oriented Aspects. Find out more at [http://archivo.dbpedia.org](http://archivo.dbpedia.org). The description for the individual files in the artifact can be found [here](http://dev.dbpedia.org/DBpedia_Archvio#files)." ; dataid:maintainer ; dataid:version ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:description "## DBpedia Archivo Ontology Snapshot\n\n| Attribute | Value |\n| - | - |\n| Ontology URI | \n| Archivo Ontology Factsheet| [Link](http://archivo.dbpedia.org/info?o=http://www.ebi.ac.uk/efo/efo.owl)\n| Snapshot File URL | \n| Snapshot OWL Version IRI | \n| Snapshot Time | 2025-02-17 22:08:05\n\nThe [DBpedia Archivo Databus agent](https://databus.dbpedia.org/ontologies) generates only basic, static documentation for the archived snapshots of the ontologies.\n\n## Ontology Metadata\n\nDBpedia Archivo extracts metadata from the ontology for well known properties (e.g. dct:description). This subsection shows the content of every property individually using a separate heading.\n\n### rdfs:comment\n\n2025-02-17" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:publisher ; dct:title "http://www.ebi.ac.uk/efo/efo.owl"@en ; dcat:distribution , , , , , , , , , , , , , , , , , , , . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "sorted" , "parsed" ; dataid:file ; dataid:formatExtension "nt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview " \"GAZ:00002845\" .\n .\n \"China\" .\n \"China\"@en .\n .\n \"GAZ:00002839\" .\n .\n \"India\" .\n \"India\"@en .\n ." ; dataid:sha256sum "8cde8a42c1a7e248c62d9c808bfe9b163cf16451e4da101ae78f9fe52606bd67" ; dataid:signature "dhKrG9Hu1gEFpxlAN0otRBzn9PyjFu46B7uFkLEDl5gw8WPxuK5eaU1L61/Xje/7oQ1TgGw14I2Z7P++0UospBwTX6Yc1eA4jwoR9ZJSEOKV+W3gKuW6bg68mHHplASgZ6BHa18iTwPqwVDCq0UZrwBgKSkHdGJg9xM6vAILQDkj3mbv7HeFmoDnN8b7GZfNK+xRq/KLKUOtJJc7kLqQP3McgIKTvmTeQbSD94iqpQ1Z35GrKf1bQCRdHrA6b4zl1bPB4h7IKt+y2bap9HO+i8549tCQeFhWELswKvH1SeL927RkKf/X/pWaijQ4YL/lCj3NGovWnQA70Wy+J83NfQ==" ; dataid-cv:tag "sorted" ; dataid-cv:type "parsed" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:09:18Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "336367661"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationNTriples . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "NONE" , "pelletInfo" ; dataid:file ; dataid:formatExtension "txt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "WARNING: An illegal reflective access operation has occurred\nWARNING: Illegal reflective access by com.google.inject.internal.cglib.core.$ReflectUtils$2 (file:/usr/lib/pellet/cli/target/pelletcli/lib/guice-4.0.jar) to method java.lang.ClassLoader.defineClass(java.lang.String,byte[],int,int,java.security.ProtectionDomain)\nWARNING: Please consider reporting this to the maintainers of com.google.inject.internal.cglib.core.$ReflectUtils$2\nWARNING: Use --illegal-access=warn to enable warnings of further illegal reflective access operations\nWARNING: All illegal access operations will be denied in a future release\n[main] WARN org.semanticweb.owlapi.util.SAXParsers - http://www.oracle.com/xml/jaxp/properties/entityExpansionLimit not supported by parser type org.apache.xerces.jaxp.SAXParserImpl\n[main] WARN org.semanticweb.owlapi.util.SAXParsers - entityExpansionLimit not supported by parser type org.apache.xerces.jaxp.SAXParserImpl\n[main] WARN org.semanticweb.owlapi.util.SAXParsers - http://www.oracle.com/xml/jaxp/properties/entityExpansionLimit not supported by parser type org.apache.xerces.jaxp.SAXParserImpl\n[main] WARN org.semanticweb.owlapi.util.SAXParsers - entityExpansionLimit not supported by parser type org.apache.xerces.jaxp.SAXParserImpl\n[main] ERROR org.semanticweb.owlapi.rdf.rdfxml.parser.OWLRDFConsumer - Entity not properly recognized, missing triples in input? http://org.semanticweb.owlapi/error#Error1 for type Class" ; dataid:sha256sum "f020b0280421c62a5055bdd3c2cb03c750b3088ebf5a93e5267c95140516c947" ; dataid:signature "HjODYKXS2A+bspiXhDnB/IpWPLlTKwwuY9kgUDt7xVRSQuYy7z0OH0QpF3oTstMDxveyKU8HZIau6LZPBWP4QkbDZx6R5brxaLiVsIZTxFqvaCCM/Pv6k5okLcCEephG7nmBRl4iPCLYZcBwt8PiJtvTM3U3nGzxEIir5VJEPcTWLlZ3Hln3bGfRquuTYkb8REdk3Pt9Q71OW3ZODO7MLshN5G1nS604JDUlWSAqlC9TgxrIXbm27WPAwaYLq5vDco9ongpF/f5VamZfL2pTFvfYhB+pcB9oa0T7Yo2m8mhsk/hJ079fHYfiANjXkU1ZQr3Abvp9imWJQFQtjJxlQA==" ; dataid-cv:imports "NONE" ; dataid-cv:type "pelletInfo" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:41:42Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "111447"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:TextPlain . a dataid:Artifact . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "meta" ; dataid:file ; dataid:formatExtension "json" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "{\n \"http-data\": {\n \"accessed\": \"2025.02.17; 22:08:42\",\n \"best-header\": \"application/rdf+xml\",\n \"content-length\": \"232113685\",\n \"e-tag\": \"\\\"0x8DD4F6C79C2F3AD\\\"\",\n \"lastModified\": \"Mon, 17 Feb 2025 16:02:27 GMT\"\n },\n \"logs\": {\n \"nir-header\": \"{'Content-Type': 'text/html', 'Date': 'Mon, 17 Feb 2025 22:08:05 GMT', 'Location': 'https://www.ebi.ac.uk/efo/efo.owl', 'Connection': 'Keep-Alive', 'Content-Length': '0'}\"," ; dataid:sha256sum "2b74ef088202685497764e51a4802917e6e72e47ef0177c580833d999c3e9d5f" ; dataid:signature "nB8VAby2xIfhLwmfOrGsKRYE5OxVHY5YqJ7Avw2dGRUCmMVTOJBAUAcgCsND3slU3IwLipVontUTu6KYJuNQE5LIOqd2mcbHZxqe07GAAr4aOHaoLSIdbYMMIGZzrTBiCddiexN2RaF0XGov0UQHSkWTeObYDFUdfbHZf/p3bv7ZXz7d+pWqOn35PjCWN51+8RAPErpoMA9NAPqYK7j0sQUCeWmRxF8KgeF6+G7+3ntA6TFi0RGLf93l6TqtRgeJSWCwWcbUMJYYPhfkhusbg/TYgx/6Va7IeG8amWszubhbzC9G/mUJZgl1CNQ0erbwaybgDCC14HjekI/Bj8QxRg==" ; dataid-cv:type "meta" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:42:32Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "2361"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationJson . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "shaclReport" , "minLicense" ; dataid:file ; dataid:formatExtension "ttl" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "@prefix sh: .\n@prefix xsd: .\n\n[] a sh:ValidationReport ;\n sh:conforms true .\n\n" ; dataid:sha256sum "8cc7623326d727b72062b0d9a0514eae24060b5f3e9945d603fa8b2c551fe965" ; dataid:signature "adeW/RUz6MuVcNVk7PfjWZUKe31AjPDp8kR30NTgcpCRmxjWt2Bo0zLhNxt9M3KTUN0zfxvoXjXoKs7DqnAvkD5L9XopzTo+bDrWO0LDHJh80ldW8VlMuaFchgTHBaAqyzMKHJVDHJSpsPCEhpGkg50bT8TpY4NepaOxyOzYqEPNcqgYODrElsNJQ3k6ptDsh9mBc4rlOD/T4KKyDmepLSx635mihyr/OX0RAjDSmiMvjO+T4r8/p2P+ljq79GFrqQy6swubqDJQVFq+VDZinFY9rNAVpFxM5vAnxuN1fCaufXLUK48jDNXG38guo4DutK6w6ajqjiiNnzvdj2mRxg==" ; dataid-cv:type "shaclReport" ; dataid-cv:validates "minLicense" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:26:21Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "148"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationNTriples . a dataid:DataId ; rdfs:comment "Metadata created by the DBpedia Databus Maven Plugin: https://github.com/dbpedia/databus-maven-plugin (Version 1.3-SNAPSHOT)\nThe DataID ontology is a metadata omnibus, which can be extended to be interoperable with all metadata formats\nNote that the metadata (the dataid.ttl file) is always CC-0, the files are licensed individually\nMetadata created by https://yum-yab.github.io/webid.ttl#onto" ; rdfs:label "DataID metadata for ebi.ac.uk/efo--efo--owl"@en ; dataid:associatedAgent ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "1.3-SNAPSHOT" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:publisher ; dct:title "DataID metadata for ebi.ac.uk/efo--efo--owl"@en . dataid-cv:type rdfs:subPropertyOf dataid:contentVariant . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "archivoMetadata" , "shaclReport" ; dataid:file ; dataid:formatExtension "ttl" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview "@prefix sh: .\n@prefix xsd: .\n\n[] a sh:ValidationReport ;\n sh:conforms false ;\n sh:result [ a sh:ValidationResult ;\n sh:focusNode ;\n sh:resultMessage \"Archivo requires either dct:abstract, dct:description or dc:description for a short comment about the ontology.\"@en ;\n sh:resultSeverity sh:Violation ;\n sh:sourceConstraintComponent sh:OrConstraintComponent ;" ; dataid:sha256sum "6ab88604592cb81b5978b7dc1d75ce7aafb3523a92337a4c600b66d0b449cb10" ; dataid:signature "t/OFd1+FSfbvGnd8dkenBu9z3P5U0UrNPTSvQqLvXvV8gj/YgTnkKzj4s504zAShFuFESnKi0VC03hLbp5lN3vTGUfkeLd9QuYGWKTGj/t566xaIRr/ldkZHl9DxKVIBUD6MkUgUlXTnjMxDRTInW8CcB56C4Wxbopq+TPAAgQjqv9ERGR3/YF9oEMlgn4y1Q/l7TF1yS+F0dIf1GuI6295qBn2gpBozcYOmsAI9qbL17hZpthB8WFwBY4h9+Wo2eXIVdivIJ5jzi+9bHZc7VLMBPYA+Bg4DQn2ZQVfNiY8QdE+lbBGYFWOLUaLlpj7gOiHbKtrA8LZIc4BY0PtjZA==" ; dataid-cv:type "shaclReport" ; dataid-cv:validates "archivoMetadata" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:23:44Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "1305"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationNTriples . a dataid:SingleFile ; dataid:associatedAgent ; dataid:compression "None" ; dataid:contentVariant "diff" , "new" ; dataid:file ; dataid:formatExtension "nt" ; dataid:isDistributionOf ; dataid:maintainer ; dataid:preview " \"Male germ cells are specialized cells that give rise to the male gametes and are therefore crucial for sexual reproduction in males. Through a complex process called spermatogenesis in the testes male germ cells undergo several stages of development, each with distinctive morphological and physiological characteristics, eventually differentiating into mature spermatozoa (sperm). \\nMale germ cells are responsible for transferring genetic material from male to offspring as part of sexual reproduction. In the initial stage of their life cycle, they exist as spermatogonial stem cells, which multiply by mitotic division to self-renew and to produce daughter cells. The daughter cells then undergo meiotic division, a process that reduces the number of chromosomes in each cell by half, from diploid to haploid \\u2013 the formation of spermatids. This is critical for maintaining genetic stability from generation to generation, as it ensures that when an egg and sperm cell unite during fertilization, the resulting offspring will have the correct number of chromosomes. The final phase of spermatogenesis is called spermiogenesis, during which spermatozoa - mature and motile sperm cells \\u2013 are produced from round spermatids. \\nThe matured male germ cells or sperm cells are highly specialized, having a streamlined shape designed for efficient movement towards the female egg. A sperm cell is divided into three main parts, namely the head, midpiece, and tail. The head contains the genetic material, the midpiece contains mitochondria that provide energy, and the tail, termed as the flagellum, propels the sperm cell forward. Each of these parts play significant roles in fertilization.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Sperm cells, also known as spermatozoa or male gametes, are highly specialized cells that are pivotal for sexual reproduction in animals. Produced in the male reproductive organs, specifically the testes, sperm cells play an important role in the process of fertilization, where they fuse with a female gamete or egg cell (ovum) to form a zygote, which marks the beginning of a new organism.\\nSperm cells hold several unique traits that set them apart from other body cells. Structurally, a sperm cell possesses two main structures: the head, containing the nucleus carrying the paternal genetic information, and the flagellum, which generates energy and grants the sperm cell mobility\\nThe process of fertilization occurs when one sperm cell successfully penetrates the egg, delivering its genetic information, and ultimately leading to the formation of a new individual combining both paternal and maternal genetic materials. Notably, while hundreds of millions of sperm cells may be released during ejaculation, only one has the opportunity to successfully fertilize the egg, underscoring the highly competitive nature of this biological process.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Kupffer cells are tissue-resident macrophages located in the liver. They are an integral part of the mononuclear phagocyte system and are responsible for the phagocytosis of dead or dying cells, microbes, and other foreign substances. Kupffer cells account for approximately 80-90% of tissue-resident macrophages in the body. They are found within the lumen of liver sinusoids and interface with microbial populations and products.\\nThe primary role of Kupffer cells is to maintain homeostasis in the liver. They continuously filter and cleanse the blood that flows through the liver, removing pathogens, endotoxins, particulate matter, aged and dysfunctional red blood cells, and miscellaneous waste products. These cells also play an important role in maintaining iron homeostasis. During the process of phagocytosis, Kupffer cells recycle iron from degraded red blood cells, which is then utilized in the formation of new erythrocytes.\\nKupffer cells also play key roles in various immune responses and inflammatory processes. They secrete various types of cytokines and chemokines, which contribute to the activation and mobilization of other immune cells. They can also produce reactive oxygen species and nitric oxide, which have microbicidal actions. Although their activity is essential for host defense, excessive or prolonged activation of Kupffer cells may contribute to hepatic injury, inflammation, and fibrosis.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Osteoclasts, derived from the monocyte/macrophage lineage, play a crucial role in bone remodeling through bone resorption. They are distinguished from other cells by their large size and their unique ability to secrete enzymes and acids that dissolve the calcium phosphate in bone. The formation of osteoclasts is influenced by two primary factors: macrophage colony-stimulating factor (M-CSF) and the ligand-activated receptor (RANKL) of nuclear factor kappa B (NF-\\u03BAB).\\nOsteoclasts also collaborate with osteoblasts, responsible for new bone formation, to maintain bone health and adapt bone structure. Their coordinated actions allow continuous remodeling while preserving overall bone strength and integrity. Imbalances in osteoclast activity can lead to pathological conditions. For example, excessive activity may contribute to diseases like osteoporosis, periprosthetic osteolysis, bone tumors, and Paget's disease. Other the other hand, osteoclast deficiency ca result in conditions like osteopetrosis.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Glial cells, also known as neuroglia or simply glia, are non-neuronal cells in the central and peripheral nervous systems that provide support and protection for neurons. They constitute approximately half of the total cells in the human brain and more than half in other parts of the nervous system. Glial cells perform several key functions including, but not limited to, maintaining homeostasis, forming the myelin sheath around the neuron axons, and providing support and nutrition to neurons.\\nThese different functions are performed by various glial cell types, including astrocytes, oligodendrocytes, microglia and other specialized types. Astrocytes, for example, are the most abundant glial cells and provide metabolic and nutrient support to neurons, help regulate the extracellular ion and neurotransmitter levels, and play a role in the formation and maintenance of the blood-brain barrier, contributing to the overall homeostasis and functioning of the nervous system. Additionally, astrocytes are involved in synaptic communication and participate in processes such as synaptogenesis and synaptic pruning.\\nOligodendrocytes in the central nervous system function to insulate neurons by producing a fatty substance known as myelin. The myelin sheath enhances the speed and efficiency of nerve impulse conduction along the axons. \\nMicroglia, the immune cells of the central nervous system, protect neurons from pathogens and clear away dead neurons through phagocytosis, a process also known as cellular eating. They also contribute to the regulation of inflammation in response to signals of tissue damage or infection in the central nervous system by releasing cytokines and other signaling molecules that modulate the immune response.\\nDespite their overarching function in the support and protection of neurons, glial cells have also been shown to play significant roles in the pathophysiology of many psychiatric and neurodegenerative diseases, such as Alzheimer\\u2019s, Parkinson\\u2019s Disease and multiple sclerosis.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Microglial cells, sometimes referred to as microglia, are a type of glial cell that primarily exist within the central nervous system (CNS), notably in the brain and the spinal cord. Classified among the resident immune cells, microglial cells represent about 10% of all cells found within the CNS. These cells are derived from progenitor cells in the yolk sac, which differentiates them from other types of glial cells (such as astrocytes and oligodendrocytes) that are derived from neuroectodermal cell lineages. \\nThe primary role of microglial cells is to act as the first and main active form of immune defense in the CNS. They express a vast repertoire of pattern recognition receptors, which allow them to sense and eliminate microbes invading the CNS parenchyma. They represent one of the macrophage populations of the CNS and are responsible for phagocytosis (engulfing and destroying cellular waste or pathogens) in the neural environment. \\nMicroglial cells are particularly responsive to pathogens and injuries and change their morphology in reaction to inflammation or insult: In the normal state they are characterized by a ramified shape with small processes; in response to stimuli, some microglia mature and change to an amoeboid shape. \\nBeyond their macrophagic activity, they also perform synaptic pruning during brain development, eliminate unnecessarily produced neurons, and facilitate tissue regeneration and repair. they play integral roles in regulating neural development and supporting cell survival and are important for maintaining tissue homeostasis. \\nWhile their protective role generally benefits the brain, their over-activation can occasionally lead to neuro-inflammatory diseases, underlining the importance of balanced microglial cell functions. They have been extensively studied for their association with neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Melanocytes are specialized cells prevalently found in the skin, but also present in the hair follicles, eyes, inner ear, bones, heart, and brain. Their primary function is the synthesis of melanin, a pigment responsible for coloration of skin, hair, and eyes. The presence and distribution of this pigment play a crucial role in the body's defense mechanism against harmful ultraviolet radiation.\\nIn addition to melanin production, melanocytes also engage in a variety of other biological functions. They play a fundamental role in the immune response, owing to their ability to present antigens to T cells. Furthermore, they contribute to the maintenance of the skin's homeostasis by regulating processes such as extracellular matrix remodeling and cytokine production. A balance in melanocyte function is pivotal, as dysfunctions often result in dermatological disorders. For instance, the loss of melanocytes or reduction in their function may lead to hypopigmentation conditions such as vitiligo, whereas an abnormal increase could result in hyperpigmentation disorders or melanoma, a dangerous type of skin cancer.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Goblet cells are specialized, simple columnar, secretory epithelial cells that are mostly found in the respiratory and intestinal tracts. The term \\\"goblet\\\" refers to their shape, which resembles a flask or goblet, specially at their apical end which is swollen due to the accumulation of secretory granules. \\nThe primary function of goblet cells is to to protect and lubricate the underlying tissues by secreting large quantities of mucin, a complex glycoprotein, which forms mucus when hydrated. In the respiratory tract, the mucus secreted by these cells traps dust, bacteria, viruses, and other potentially harmful particles in the inhaled air, preventing them from reaching the delicate tissues of the lungs. In the intestines, the goblet cells secrete mucus that acts as a protective barrier shielding the intestinal epithelium from dietary antigens, pathogens and prevents the intestinal epithelium from being eroded by the actions of the digestive enzymes and the abrasive action of passing food material.\\nGoblet cells are capable of rapidly altering their secretory output in response to stimuli. For example, irritants like smoke or dust can trigger an increased rate of mucus production, as the body attempts to flush out the harmful particles. Conversely, in conditions such as chronic bronchitis and cystic fibrosis, overactive goblet cells can create a thick accumulation of mucus that obstructs the airways and fosters bacterial growth. Lastly, goblet cells are not static, rather, they undergo a dynamic process known as goblet cell metaplasia-differentiation, wherein non-goblet cells in response to chronic injury or inflammation, can differentiate into goblet cells leading to an accumulation of these cells in the tissue, known as goblet cell hyperplasia.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Chromaffin cells, also known as pheochromocytes, are neuroendocrine cells that are typically located in the adrenal medulla, the innermost part of the adrenal gland, which is situated on top of each kidney. Chromaffin cells are also found in small clusters, known as paraganglia, in various locations throughout the body, including the sympathetic nervous system. They derive their name from their ability to stain a brownish-black color upon exposure to chromic salts, a feature made possible due to their high content of granules rich in catecholamines and catecholamine-related neurotransmitters.\\nThe primary function of chromaffin cells is the synthesis and release of catecholamines, specifically epinephrine (adrenaline) and norepinephrine (noradrenaline). These neurotransmitters are vital stress hormones that, when released by the adrenal chromaffing cells into the bloodstream, prepare the body for the 'fight or flight' response. This response can enhance the body's performance in a dangerous situation by increasing heart rate, elevating blood sugar, and increasing blood flow to the muscles. The chromaffin cells in paraganglia are responsible for the local release of catecholamines and play a role in regulating blood pressure and other autonomic functions.\\nIn addition to their role in stress response, chromaffin cells also contribute to the body's immune response. They secrete several peptides including antimicrobial peptides, and the discovery of LPS and cytokine receptors on chromaffin cells suggests that the adrenal medulla may participate in some aspects of the immune response.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" .\n \"Leydig cells are a testosterone-secreting cell in the interstitial area in the testes of males. They are named after Franz Leydig, a German anatomist who discovered these cells in 1850. Uniquely situated within the soft connective tissue surrounding the seminiferous tubules, Leydig cells form an integral part of the male reproductive system. They are usually polygonal cells characterized by well developed smooth endoplasmic reticulum, high lipid content and a large round nucleus. They are found across mammalian species, including humans. \\nThe primary function of Leydig cells is the production of androgens, the male sex hormones, the most notable of which is testosterone. Leydig cells synthesize testosterone from cholesterol through a series of enzymatic reactions. The production and release of testosterone are mainly regulated by the luteinizing hormone (LH) released by the anterior pituitary gland. In response to LH, Leydig cells convert cholesterol into testosterone, which then plays a crucial role in the development and maintenance of primary and secondary male sexual characteristics. These include the formation and maturation of male reproductive organs, onset of spermatogenesis, and the presentation of male secondary sexual traits such as the deepening of the voice, growth of facial hair, development of muscles, and a broadening of shoulders.\\nApart from testosterone production, Leydig cells also secrete insulin-like factor 3 (INSL3) that is essential for testicular descent during embryonic development in males. Dysregulation or loss of Leydig cells can lead to numerous conditions like testosterone deficiency, infertility, and certain forms of testicular cancer. Although not typical, Leydig cells can regenerate if they are damaged, ensuring the continuous production of testosterone and maintaining male reproductive health. They provide an excellent model to study cell differentiation and hormone regulation, thereby enhancing our understanding of reproductive biology and associated disorders.\\n\\n(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)\" ." ; dataid:sha256sum "527c2d7131914f745a0ffd5c0323733cf6b6fdaf0fede94ad13bb5944e576452" ; dataid:signature "WF6u0ULuz5uqGh32npmneuPClN2WxN/KcDJ2lV0f4cTo1nUt1Kj22cPQbH1WHGQJBJZKWjUJSd4QwQ0zJOVE4W0EPVRoChzSdsKek9/L+mB9zXxFNOjOhH0q+3IySJOFi3N5XekBuqVNEWt7nSDeuWxd8ogfj7NSQpcahUAaNLvIp4XRG0Vtgq6lXN78ICFCjFBrzZoxk4S/QINOo0r2x91jYoYvcDEkjOLKWfcHLo5xQ2Z5SgSHJ9etyBlhCRKUq9lQ+HhYMa+ihhkklXZrRdL+0VEmYTQf3l518vmhcpDh48kThIRymwKn2w7dSqTbZcso0zuyh0sA7mHm/yPXUA==" ; dataid-cv:triples "new" ; dataid-cv:type "diff" ; dct:conformsTo "http://dataid.dbpedia.org/ns/core#" ; dct:hasVersion "2025.02.17-220805" ; dct:issued "2025-02-17T22:56:08Z"^^xsd:dateTime ; dct:license ; dct:modified "2025-02-17T22:11:37Z"^^xsd:dateTime ; dct:publisher ; dcat:byteSize "160224877"^^xsd:decimal ; dcat:downloadURL ; dcat:mediaType dataid-mt:ApplicationNTriples .