Core Ontology for Biology and Biomedicine

IRI:
http://purl.obolibrary.org/obo/cob.owl
Current version:
2021-02-21
Other visualisation:
Ontology source

Table of Content

  1. Introduction
  2. Classes
  3. Object Properties
  4. Data Properties
  5. Annotation Properties
  6. Namespace Declarations

Introduction

COB brings together key terms from a wide range of OBO projects to improve interoperability.

Classes

action specificationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000077

has super-classes
directive information entityc
has partop some action specificationc
has partop some objective specificationc

assayc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000107

has super-classes
completely executed planned processc
has specified outputop some measurement datumc and (is aboutop some material entityc and (has characteristicop some evaluant rolec))
has specified inputop some material entityc and (has characteristicop some evaluant rolec)

atomc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000011

This atom is closely related to ChEBI's atom, but not exactly equivalent to.
is equivalent to
has number of atomic nucleidp value 1
has super-classes
material entityc
has partop some atomic nucleusc
has sub-classes
monoatomic ionc, uncharged atomc
is in domain of
has atomic numberdp
is disjoint with
molecular entityc

atomic nucleusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000012

This is equivalent to CHEBI:33252
has super-classes
subatomic particlec

biological processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000037

A biological process is an evolved process
has super-classes
processc
(has participantop some organismc) or (has participantop some part ofop some organismc) or (occurs inop some organismc)
has partop some gene product or complex activityc
is disjoint with
gene product or complex activityc, environmental processc, physico-chemical processc

cellc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000017

We struggled with this definition. We are worried about circularity. We also considered requiring the capability of metabolism.
has super-classes
material entityc
has sub-classes
cell in vitroc, native cellc

cell in vitroc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000019

has super-classes
cellc

cell nucleusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000103

has super-classes
subcellular structurec

cellular membranec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000116

has super-classes
subcellular structurec

cellular organismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000118

has super-classes
organismc

characteristicc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000502

has super-classes
thingc
inverse has characteristicop some thingc
has partop only characteristicc
has sub-classes
information representationc, qualityc, realizablec
is in domain of
has quantitydp
is in range of
has characteristicop

chargec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000004

has super-classes
qualityc

collection of organismsc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000055

has super-classes
material entityc

completely executed planned processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000035

has super-classes
realizablec
planned processc
realizesop some planc
has sub-classes
assayc, data transformationc, investigationc, material processingc
is in domain of
has specified inputop, has specified outputop
is disjoint with
failed planned processc

complex of molecular entitiesc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000080

has super-classes
material entityc
has partop some molecular entityc
has sub-classes
protein-containing macromolecular complexc

conclusion based on datac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000058

has super-classes
informationc

data itemc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000102

has super-classes
informationc
has sub-classes
measurement datumc

data transformationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000108

has super-classes
completely executed planned processc

directive information entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000069

has super-classes
informationc
has sub-classes
action specificationc, objective specificationc, plan specificationc

disease coursec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000064

has super-classes
processc

disease diagnosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000062

has super-classes
informationc

dispositionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000111

has super-classes
realizablec
has sub-classes
functionc

documentc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000101

has super-classes
informationc

drug productc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000088

has super-classes
processed material entityc

ecosystemc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000067

has super-classes
material entityc

electronc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000010

has super-classes
subatomic particlec
has number of atomic nucleidp value 0

environmental processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000065

has super-classes
processc
is disjoint with
biological processc, gene product or complex activityc, physico-chemical processc

evaluant rolec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000119

has super-classes
rolec

failed planned processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000083

has super-classes
planned processc
is disjoint with
completely executed planned processc

functionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000112

has super-classes
dispositionc

gene productc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000073

has super-classes
molecular entityc

gene product or complex activityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000038

This is the same as GO molecular function
has super-classes
processc
enabled byop some gene productc or protein-containing macromolecular complexc
is disjoint with
biological processc, environmental processc, physico-chemical processc

geographical locationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000032

has super-classes
immaterial entityc

geophysical entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000068

has super-classes
material entityc

gross anatomical partc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000021

Bodily fluids, such as urine, are currently defined as anatomical entities in UBERON. We should make sure there is a proper home for these here.
has super-classes
material entityc

immaterial anatomical entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000056

has super-classes
immaterial entityc

immaterial entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000031

has super-classes
thingc
has sub-classes
geographical locationc, immaterial anatomical entityc, sitec

informationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000061

Pier: 'data, information or knowledge'. OR 'representation
has super-classes
thingc
inverse concretizesop some information representationc
is aboutop some thingc
has sub-classes
conclusion based on datac, data itemc, directive information entityc, disease diagnosisc, documentc, phenotypic findingc

information representationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000120

This captures: pattern of writing in a book; neural state in the brain, electronic charges in computer memory etc
is equivalent to
concretizesop some informationc
has super-classes
characteristicc
has sub-classes
planc

investigationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000109

has super-classes
completely executed planned processc

massc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000003

has super-classes
qualityc

material entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000006

is equivalent to
has qualityop some massc
has super-classes
thingc
has sub-classes
atomc, cellc, collection of organismsc, complex of molecular entitiesc, ecosystemc, geophysical entityc, gross anatomical partc, molecular entityc, organismc, organizationc, physical information carrierc, processed material entityc, subatomic particlec, subcellular structurec
is in domain of
has number of atomic nucleidp

material processingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000110

has super-classes
completely executed planned processc

measurement datumc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000121

has super-classes
data itemc

molecular entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000013

This molecular entity is different than ChEBI's 'molecular entity'.
has super-classes
material entityc
has partop some atomc
has sub-classes
gene productc, nucleic acid polymerc, proteinc
is disjoint with
atomc

monoatomic ionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000042

is equivalent to
atomc and (has qualityop some chargec)
has super-classes
atomc
is disjoint with
uncharged atomc

native cellc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000018

has super-classes
cellc

neutronc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000009

has super-classes
subatomic particlec

nucleic acid polymerc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000049

has super-classes
molecular entityc

objective specificationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000076

has super-classes
directive information entityc

obsolete macromolecular entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000014

Terms moved to 'molecular entity', see https://github.com/OBOFoundry/Experimental-OBO-Core/issues/33
has super-classes
thingc

obsolete_elementary chargec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000005

has super-classes
thingc

organismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000022

Includes virus - we will later have a class for cellular organisms.
has super-classes
material entityc
has sub-classes
cellular organismc

organizationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000025

Should revisit if we can place outside of material entity - a collection of roles.
has super-classes
material entityc

phenotypic findingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000063

has super-classes
informationc

physical information carrierc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000122

is equivalent to
has characteristicop some concretizesop some informationc
has super-classes
material entityc

physico-chemical processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000066

This is meant to capture processes that are more fundamental than macromolecular activities
has super-classes
processc
is disjoint with
biological processc, gene product or complex activityc, environmental processc

planc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000113

has super-classes
realizablec
information representationc
concretizesop some plan specificationc
inverse realizesop only planned processc

plan specificationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000079

has super-classes
directive information entityc
has partop some objective specificationc
has partop some action specificationc

planned processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000082

Should we create agent?
has super-classes
processc
intended to realizeop some planc
has sub-classes
completely executed planned processc, failed planned processc

processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000034

has super-classes
thingc
part ofop only processc
has sub-classes
biological processc, disease coursec, environmental processc, gene product or complex activityc, physico-chemical processc, planned processc
is in domain of
has participantop, occurs inop
is in range of
realizesop

processed material entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000026

has super-classes
material entityc
has sub-classes
drug productc

proteinc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000015

has super-classes
molecular entityc

protein-containing macromolecular complexc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000075

This is not covalently bonded, which conflicts with changes to the parent definition.
has super-classes
complex of molecular entitiesc
has partop some gene productc

protonc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000008

has super-classes
subatomic particlec

qualityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000001

has super-classes
characteristicc
has sub-classes
chargec, massc
is in range of
has qualityop

realizablec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000033

has super-classes
characteristicc
has sub-classes
completely executed planned processc, dispositionc, planc, rolec
is in domain of
realizesop

rolec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000114

has super-classes
realizablec
has sub-classes
evaluant rolec

sitec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000057

has super-classes
immaterial entityc

subatomic particlec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000007

has super-classes
material entityc
has sub-classes
atomic nucleusc, electronc, neutronc, protonc

subcellular structurec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000020

Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes.
has super-classes
material entityc
has partop some molecular entityc
has sub-classes
cell nucleusc, cellular membranec

uncharged atomc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000043

is equivalent to
atomc and (not (has qualityop some chargec))
has super-classes
atomc
is disjoint with
monoatomic ionc

Object Properties

characteristic ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000023

is inverse of
has characteristicop

concretizesop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000078

is inverse of
is concretized asop

contains processop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000036

is inverse of
occurs inop

enabled byop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000074

has super-properties
has participantop

executed byop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000016

is inverse of
executesop

executesop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000086

is inverse of
executed byop
has sub-property chains
realizesop o concretizesop

has characteristicop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000512

has characteristics: inverse functional

has domain
thingc
has range
characteristicc
is inverse of
characteristic ofop

has partop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000047

is inverse of
part ofop

has participantop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000070

has sub-properties
enabled byop, has specified inputop, has specified outputop
has domain
processc
is inverse of
participates inop

has planop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000084

has qualityop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000041

Note: this will end up being a subproperty of has-characteristic when we add it, TBD depends on discussion of whether has-characteristic is functional
has range
qualityc
is inverse of
quality ofop

has specified inputop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000039

has super-properties
has participantop
has domain
completely executed planned processc
is inverse of
is specified input ofop

has specified outputop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000040

has super-properties
has participantop
has domain
completely executed planned processc
is inverse of
is specified output ofop

intended plan process typeop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000085

intended to realizeop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000081

is aboutop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000513

is concretized asop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000002

is inverse of
concretizesop

is specified input ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000027

has super-properties
participates inop
is inverse of
has specified inputop

is specified output ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000028

has super-properties
participates inop
is inverse of
has specified outputop

occurs inop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000071

has domain
processc
is inverse of
contains processop

part ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000072

has characteristics: transitive

is inverse of
has partop

participates inop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000024

has sub-properties
is specified input ofop, is specified output ofop
is inverse of
has participantop

quality ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000030

is inverse of
has qualityop

realized inop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000029

is inverse of
realizesop

realizesop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000087

has domain
realizablec
has range
processc
is inverse of
realized inop

Data Properties

has atomic numberdp back to ToC or Data Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000800

We are undecided as to whether to ultimately model this as a data property of object property + cardinality, but for now we are using DPs as these are faster for reasoning
has domain
atomc
has range
non negative integer

has inchi stringdp back to ToC or Data Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000803

has super-properties
top data property

has number of atomic nucleidp back to ToC or Data Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000801

has domain
material entityc
has range
non negative integer

has quantitydp back to ToC or Data Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000511

The range of this property should be a user-defined unit datatype, e.g 182^:cm
has domain
characteristicc

Annotation Properties

c o b based onap back to ToC or Annotation Property ToC

IRI: http://purl.obolibrary.org/obo/COB_based_on

definitionap back to ToC or Annotation Property ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000115

descriptionap back to ToC or Annotation Property ToC

IRI: http://purl.org/dc/elements/1.1/description

exact matchap back to ToC or Annotation Property ToC

IRI: http://www.w3.org/2004/02/skos/core#exactMatch

i a o 0000116ap back to ToC or Annotation Property ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000116

licenseap back to ToC or Annotation Property ToC

IRI: http://purl.org/dc/terms/license

titleap back to ToC or Annotation Property ToC

IRI: http://purl.org/dc/elements/1.1/title

Namespace Declarations back to ToC

default namespace
http://purl.obolibrary.org/obo/cob.owl#
dc
http://purl.org/dc/elements/1.1/
obo
http://purl.obolibrary.org/obo/
owl
http://www.w3.org/2002/07/owl#
rdf
http://www.w3.org/1999/02/22-rdf-syntax-ns#
rdfs
http://www.w3.org/2000/01/rdf-schema#
skos
http://www.w3.org/2004/02/skos/core#
terms
http://purl.org/dc/terms/
xsd
http://www.w3.org/2001/XMLSchema#

This HTML document was obtained by processing the OWL ontology source code through LODE, Live OWL Documentation Environment, developed by Silvio Peroni.