Core Ontology for Biology and Biomedicine

IRI:
http://purl.obolibrary.org/obo/cob.owl
Version IRI:
http://purl.obolibrary.org/obo/cob/releases/2022-11-02/cob.owl
Current version :
2022-11-02
Other visualisation :
Ontology source - WebVowl

Abstract

This version of COB includes native OBO URIs, only using COB IRIs where equivalent natives could not be found. To see the edition that includes native IRIs, consult cob-edit.owl.

Table of Content

  1. Introduction
  2. Classes
  3. Object Properties
  4. Data Properties
  5. Annotation Properties
  6. Namespace Declarations

Introduction

COB brings together key terms from a wide range of OBO projects to improve interoperability.

Classes

action specificationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000077

has super-classes
directive information entityc
has partop some action specificationc
has partop some objective specificationc

agent rolec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/SEPIO_0000048

has super-classes
rolec

assayc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000070

has super-classes
completely executed planned processc
has specified inputop some material entityc and (has characteristicop some evaluant rolec)
has specified outputop some measurement datumc and (is aboutop some material entityc and (has characteristicop some evaluant rolec))

atomc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000011

This atom is closely related to ChEBI's atom, but not exactly equivalent to.
is equivalent to
has number of atomic nucleidp value 1
has super-classes
material entityc
has partop some atomic nucleusc
has sub-classes
monoatomic ionc, uncharged atomc
is in domain of
has atomic numberdp
is disjoint with
molecular entityc

atomic nucleusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CHEBI_33252

Some people may be uncomfortable calling every proton an atomic nucleus
has super-classes
subatomic particlec

biological processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/GO_0008150

A biological process is an evolved process
has super-classes
processc
(occurs inop some organismc) or (has participantop some organismc) or (has participantop some part ofop some organismc)
has partop some gene product or complex activityc
is disjoint with
environmental processc, gene product or complex activityc, physico-chemical processc

cellc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CL_0000000

CL and GO definitions of cell differ based on inclusive or exclusive of cell wall, etc.
has super-classes
material entityc
has sub-classes
cell in vitroc, native cellc

cell in vitroc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CL_0001034

has super-classes
cellc

cell nucleusc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/GO_0005634

has super-classes
subcellular structurec

cellular membranec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000116

has super-classes
subcellular structurec

cellular organismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CARO_0010004

has super-classes
organismc

characteristicc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PATO_0000001

has super-classes
thingc
inverse has characteristicop some thingc
has partop only characteristicc
has sub-classes
chargec, information representationc, massc, realizablec
is in domain of
has quantitydp
is in range of
has characteristicop

chargec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PATO_0002193

has super-classes
characteristicc
characteristic ofop some material entityc

collection of organismsc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PCO_0000000

has super-classes
material entityc

completely executed planned processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000011

has super-classes
planned processc
realizesop some planc
has sub-classes
assayc, data transformationc, investigationc, material processingc
is in domain of
has specified inputop, has specified outputop
is disjoint with
failed planned processc

complex of molecular entitiesc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000080

has super-classes
material entityc
has partop some molecular entityc
has sub-classes
protein-containing macromolecular complexc
is disjoint with
molecular entityc

conclusion based on datac back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0001909

has super-classes
informationc

data itemc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000027

has super-classes
informationc
has sub-classes
measurement datumc

data transformationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0200000

has super-classes
completely executed planned processc

directive information entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000033

has super-classes
informationc
has sub-classes
action specificationc, objective specificationc, plan specificationc

disease coursec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGMS_0000063

has super-classes
processc

disease diagnosisc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGMS_0000073

has super-classes
informationc

dispositionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000016

has super-classes
realizablec
has sub-classes
functionc

documentc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000310

has super-classes
informationc

drug productc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/DRON_0000005

has super-classes
processed material entityc

ecosystemc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/ENVO_01001110

has super-classes
material entityc

electronc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CHEBI_10545

has super-classes
subatomic particlec
molecular entityc
has number of atomic nucleidp value 0

environmental processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/ENVO_02500000

has super-classes
processc
is disjoint with
gene product or complex activityc, biological processc, physico-chemical processc

evaluant rolec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000119

has super-classes
rolec

exposure of organismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0001000

has super-classes
processc

failed planned processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000083

has super-classes
planned processc
is disjoint with
completely executed planned processc

functionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000034

has super-classes
dispositionc

gene productc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000073

has super-classes
molecular entityc

gene product or complex activityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/GO_0003674

This is the same as GO molecular function
has super-classes
processc
enabled byop some gene productc or protein-containing macromolecular complexc
is disjoint with
environmental processc, biological processc, physico-chemical processc

geographical locationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000032

has super-classes
immaterial entityc

geophysical entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/ENVO_01000813

has super-classes
material entityc

gross anatomical partc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CARO_0001008

Bodily fluids, such as urine, are currently defined as anatomical entities in UBERON. We should make sure there is a proper home for these here.
has super-classes
material entityc

immaterial anatomical entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000056

has super-classes
immaterial entityc

immaterial entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000041

has super-classes
thingc
has sub-classes
geographical locationc, immaterial anatomical entityc, sitec

informationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000030

Pier: 'data, information or knowledge'. OR 'representation
has super-classes
thingc
is aboutop some thingc
inverse concretizesop some information representationc
has sub-classes
conclusion based on datac, data itemc, directive information entityc, disease diagnosisc, documentc, phenotypic findingc

information representationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000120

Pier 'representational entity'
is equivalent to
concretizesop some informationc
has super-classes
characteristicc
has sub-classes
planc

investigationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000066

has super-classes
completely executed planned processc

massc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PATO_0000125

has super-classes
characteristicc
characteristic ofop some material entityc

material entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000040

has super-classes
thingc
has sub-classes
atomc, cellc, collection of organismsc, complex of molecular entitiesc, ecosystemc, geophysical entityc, gross anatomical partc, molecular entityc, organismc, organizationc, physical information carrierc, processed material entityc, subatomic particlec, subcellular structurec
is in domain of
has number of atomic nucleidp

material processingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000094

has super-classes
completely executed planned processc

measurement datumc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000121

has super-classes
data itemc

molecular entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000013

This molecular entity is different than ChEBI's 'molecular entity'.
has super-classes
material entityc
has partop some atomc
has sub-classes
electronc, gene productc, proteinc
is disjoint with
atomc, complex of molecular entitiesc

monoatomic ionc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CHEBI_24867

has super-classes
atomc
is disjoint with
uncharged atomc

native cellc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CL_0000003

has super-classes
cellc

neutronc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CHEBI_30222

has super-classes
subatomic particlec

objective specificationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000005

has super-classes
directive information entityc

obsolete macromolecular entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000014

Terms moved to 'molecular entity', see https://github.com/OBOFoundry/Experimental-OBO-Core/issues/33
has super-classes
thingc

obsolete_elementary chargec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000005

has super-classes
thingc

organismc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0100026

"Maximal functionally integrated unit" is intended to express unity, which Barry considers synonymous with BFO 'object'.
has super-classes
material entityc
has sub-classes
cellular organismc

organizationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000245

Should revisit if we can place outside of material entity - a collection of roles.
has super-classes
material entityc

phenotypic findingc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OGMS_0000014

has super-classes
informationc

physical information carrierc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000122

is equivalent to
has characteristicop some concretizesop some informationc
has super-classes
material entityc

physico-chemical processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/MOP_0000543

This is meant to capture processes that are more fundamental than macromolecular activities
has super-classes
processc
is disjoint with
environmental processc, gene product or complex activityc, biological processc

planc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000260

has super-classes
realizablec
information representationc
concretizesop some plan specificationc
inverse realizesop only planned processc

plan specificationc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000104

has super-classes
directive information entityc
has partop some action specificationc
has partop some objective specificationc

planned processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000082

has super-classes
processc
intended to realizeop some planc
realizesop some agent rolec
has sub-classes
completely executed planned processc, failed planned processc

processc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000015

has super-classes
thingc
part ofop only processc
has sub-classes
biological processc, disease coursec, environmental processc, exposure of organismc, gene product or complex activityc, physico-chemical processc, planned processc
is in domain of
has participantop, occurs inop, realizesop

processed material entityc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000047

has super-classes
material entityc
has sub-classes
drug productc

proteinc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/PR_000000001

has super-classes
molecular entityc

protein-containing macromolecular complexc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/GO_0032991

This is not covalently bonded, which conflicts with changes to the parent definition.
has super-classes
complex of molecular entitiesc
has partop some gene productc

protonc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CHEBI_24636

has super-classes
subatomic particlec

realizablec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000017

has super-classes
characteristicc
has sub-classes
dispositionc, planc, rolec
is in range of
realizesop

rolec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000023

has super-classes
realizablec
has sub-classes
agent rolec, evaluant rolec

sitec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000029

has super-classes
immaterial entityc

subatomic particlec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CHEBI_36342

has super-classes
material entityc
has sub-classes
atomic nucleusc, electronc, neutronc, protonc

subcellular structurec back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/COB_0000020

Components are larger than individual macromolecular entities. It is tricky to define distinction between 'cell component' and 'macromolecular entity', e.g. ribosome. We would like to exclude most protein complexes.
has super-classes
material entityc
has partop some molecular entityc
has sub-classes
cell nucleusc, cellular membranec

uncharged atomc back to ToC or Class ToC

IRI: http://purl.obolibrary.org/obo/CHEBI_33250

has super-classes
atomc
is disjoint with
monoatomic ionc

Object Properties

characteristic ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000052

is inverse of
has characteristicop

concretizesop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000078

is inverse of
is concretized asop

contains processop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000067

is inverse of
occurs inop

enabled byop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002333

has super-properties
has participantop

executed byop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000016

is inverse of
executesop

executesop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/STATO_0000102

is inverse of
executed byop
has sub-property chains
realizesop o concretizesop

has characteristicop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000053

has characteristics : inverse functional

has domain
thingc
has range
characteristicc
is inverse of
characteristic ofop

has partop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000051

is inverse of
part ofop

has participantop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000057

has sub-properties
enabled byop, has specified inputop, has specified outputop
has domain
processc
is inverse of
participates inop

has planop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000084

has specified inputop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000293

has super-properties
has participantop
has domain
completely executed planned processc
is inverse of
is specified input ofop

has specified outputop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000299

has super-properties
has participantop
has domain
completely executed planned processc
is inverse of
is specified output ofop

intended plan process typeop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000085

intended to realizeop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000081

is aboutop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000136

is concretized asop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000058

is inverse of
concretizesop

is specified input ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000295

has super-properties
participates inop
is inverse of
has specified inputop

is specified output ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/OBI_0000312

has super-properties
participates inop
is inverse of
has specified outputop

occurs inop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000066

has domain
processc
is inverse of
contains processop

part ofop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000050

has characteristics : transitive

is inverse of
has partop

participates inop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000056

has sub-properties
is specified input ofop, is specified output ofop
is inverse of
has participantop

realized inop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000054

is inverse of
realizesop

realizesop back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000087

has domain
processc
has range
realizablec
is inverse of
realized inop

Data Properties

has atomic numberdp back to ToC or Data Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000800

We are undecided as to whether to ultimately model this as a data property of object property + cardinality, but for now we are using DPs as these are faster for reasoning
has domain
atomc
has range
non negative integer

has inchi stringdp back to ToC or Data Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000803

has super-properties
top data property

has number of atomic nucleidp back to ToC or Data Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000801

has domain
material entityc
has range
non negative integer

has quantitydp back to ToC or Data Property ToC

IRI: http://purl.obolibrary.org/obo/COB_0000511

The range of this property should be a user-defined unit datatype, e.g 182^:cm
has domain
characteristicc

Annotation Properties

c o b based onap back to ToC or Annotation Property ToC

IRI: http://purl.obolibrary.org/obo/COB_based_on

definitionap back to ToC or Annotation Property ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000115

descriptionap back to ToC or Annotation Property ToC

IRI: http://purl.org/dc/elements/1.1/description

exact matchap back to ToC or Annotation Property ToC

IRI: http://www.w3.org/2004/02/skos/core#exactMatch

i a o 0000116ap back to ToC or Annotation Property ToC

IRI: http://purl.obolibrary.org/obo/IAO_0000116

licenseap back to ToC or Annotation Property ToC

IRI: http://purl.org/dc/terms/license

titleap back to ToC or Annotation Property ToC

IRI: http://purl.org/dc/elements/1.1/title

Namespace Declarations back to ToC

default namespace
http://purl.obolibrary.org/obo/cob.owl#
2022-11-02
http://purl.obolibrary.org/obo/cob/releases/2022-11-02/
dc
http://purl.org/dc/elements/1.1/
obo
http://purl.obolibrary.org/obo/
owl
http://www.w3.org/2002/07/owl#
rdf
http://www.w3.org/1999/02/22-rdf-syntax-ns#
rdfs
http://www.w3.org/2000/01/rdf-schema#
skos
http://www.w3.org/2004/02/skos/core#
terms
http://purl.org/dc/terms/
xsd
http://www.w3.org/2001/XMLSchema#

This HTML document was obtained by processing the OWL ontology source code through LODE, Live OWL Documentation Environment, developed by Silvio Peroni .