http://purl.obolibrary.org/obo/eco.owl
ECO (https://github.com/evidenceontology/evidenceontology) is released into the public domain under CC0 1.0 Universal (CC0 1.0). Anyone is free to copy, modify, or distribute the work, even for commercial purposes, without asking permission. Please see the Public Domain Dedication (https://creativecommons.org/publicdomain/zero/1.0/) for an easy-to-read description of CC0 1.0 or the full legal code (https://creativecommons.org/publicdomain/zero/1.0/legalcode) for more detailed information. To get a sense of why ECO is CC0 as opposed to licensed under CC-BY, please read this thoughtful discussion (https://github.com/OBOFoundry/OBOFoundry.github.io/issues/285) on the OBO Foundry GitHub site.
URI | http://purl.obolibrary.org/obo/BFO_0000001 |
---|---|
Sub-classes |
obo:BFO_0000002c obo:BFO_0000003c |
URI | http://purl.obolibrary.org/obo/BFO_0000002 |
---|---|
Super-classes |
obo:BFO_0000001c |
Sub-classes |
obo:BFO_0000020c obo:BFO_0000004c obo:BFO_0000031c |
In domain of |
obo:RO_0000056op |
In range of |
obo:RO_0000057op |
URI | http://purl.obolibrary.org/obo/BFO_0000003 |
---|---|
Super-classes |
obo:BFO_0000001c |
Sub-classes |
obo:BFO_0000015c |
In domain of |
obo:BFO_0000062op obo:BFO_0000063op obo:RO_0000057op |
In range of |
obo:RO_0000056op obo:RO_0002222op obo:BFO_0000062op obo:BFO_0000063op |
URI | http://purl.obolibrary.org/obo/BFO_0000004 |
---|---|
Super-classes |
obo:BFO_0000002c |
Sub-classes |
obo:BFO_0000040c obo:BFO_0000141c |
In domain of |
obo:RO_0001000op obo:RO_0000087op obo:RO_0000085op |
In range of |
obo:RO_0001000op |
URI | http://purl.obolibrary.org/obo/BFO_0000015 |
---|---|
Super-classes |
obo:BFO_0000003c |
Sub-classes |
obo:GO_0003674c obo:GO_0008150c obo:OBI_0000011c |
In domain of |
obo:BFO_0000055op |
In range of |
obo:BFO_0000054op obo:IAO_0000413op |
URI | http://purl.obolibrary.org/obo/BFO_0000016 |
---|---|
Super-classes |
obo:BFO_0000017c |
Sub-classes |
obo:BFO_0000034c obo:OBI_1110093c obo:OBI_1110045c |
URI | http://purl.obolibrary.org/obo/BFO_0000017 |
---|---|
Super-classes |
obo:BFO_0000020c |
Sub-classes |
obo:BFO_0000023c obo:BFO_0000016c |
In domain of |
obo:BFO_0000054op |
In range of |
obo:BFO_0000055op |
URI | http://purl.obolibrary.org/obo/BFO_0000019 |
---|---|
Super-classes |
obo:BFO_0000020c |
Sub-classes |
obo:OBI_0000654c obo:IAO_0000015c obo:PATO_0001241c obo:PATO_0000125c |
In range of |
obo:IAO_0000221op obo:RO_0000086op |
URI | http://purl.obolibrary.org/obo/BFO_0000020 |
---|---|
Super-classes |
obo:BFO_0000002c |
Sub-classes |
obo:BFO_0000019c obo:BFO_0000017c |
In domain of |
obo:RO_0000059op |
In range of |
obo:RO_0000053op obo:RO_0000058op |
URI | http://purl.obolibrary.org/obo/BFO_0000023 |
---|---|
Super-classes |
obo:BFO_0000017c |
Sub-classes |
obo:OBI_0302732c obo:OBI_0002444c obo:OBI_0000025c obo:OBI_0000416c obo:REO_0000171c obo:OBI_1110120c obo:OBI_0302733c obo:OBI_0000097c obo:OBI_0000067c obo:OBI_0000319c obo:OBI_0000444c obo:OBI_0000086c obo:OBI_0000112c obo:OBI_0000857c |
In range of |
obo:RO_0000087op |
URI | http://purl.obolibrary.org/obo/BFO_0000029 |
---|---|
Super-classes |
obo:BFO_0000141c |
URI | http://purl.obolibrary.org/obo/BFO_0000031 |
---|---|
Super-classes |
obo:BFO_0000002c |
Sub-classes |
obo:SO_0000001c obo:IAO_0000030c |
In domain of |
obo:RO_0000058op |
In range of |
obo:RO_0000059op |
URI | http://purl.obolibrary.org/obo/BFO_0000034 |
---|---|
Super-classes |
obo:BFO_0000016c |
Sub-classes |
obo:OBI_0000391c obo:OBI_0000370c obo:OBI_0000369c obo:OBI_0000374c obo:OBI_0000372c obo:OBI_0000376c obo:OBI_0000453c obo:OBI_0000385c obo:OBI_0000401c obo:OBI_0000379c obo:OBI_0000387c obo:OBI_0000377c obo:OBI_0000371c obo:OBI_0000399c |
In domain of |
obo:RO_0000079op |
In range of |
obo:RO_0000085op |
URI | http://purl.obolibrary.org/obo/BFO_0000040 |
---|---|
Super-classes |
obo:BFO_0000004c |
Sub-classes |
obo:OBI_0002076c obo:OBI_0000245c obo:OBI_0302729c obo:CL_0000000c obo:OBI_0100051c obo:OBI_0000997c obo:GO_0005575c obo:CHEBI_33250c obo:OBI_0100026c obo:UBERON_0000465c obo:OBI_1110109c obo:OBI_1110001c obo:OBI_1110108c obo:OBI_0000427c obo:CHEBI_23367c obo:OBI_1110034c obo:IAO_0000178c obo:OBI_0000576c obo:UBERON_0000477c obo:OBI_0000047c obo:IDO_0000586c |
In domain of |
obo:OBI_0000304op obo:OBI_1110119op obo:OBI_0000647op |
In range of |
obo:OBI_1110119op |
URI | http://purl.obolibrary.org/obo/BFO_0000141 |
---|---|
Super-classes |
obo:BFO_0000004c |
Sub-classes |
obo:BFO_0000029c |
URI | http://purl.obolibrary.org/obo/CHEBI_15422 |
---|---|
Super-classes |
obo:CHEBI_23367c |
URI | http://purl.obolibrary.org/obo/CHEBI_16670 |
---|---|
Super-classes |
obo:CHEBI_33839c |
Sub-classes |
obo:PR_000000001c |
URI | http://purl.obolibrary.org/obo/CHEBI_16991 |
---|---|
Super-classes |
obo:CHEBI_33696c |
Sub-classes |
obo:OBI_0000809c obo:CHEBI_4705c |
URI | http://purl.obolibrary.org/obo/CHEBI_23367 |
---|---|
Super-classes |
obo:BFO_0000040c |
Sub-classes |
obo:CHEBI_23528c obo:CHEBI_53526c obo:CHEBI_28619c obo:CHEBI_472552c obo:CHEBI_33839c obo:CHEBI_15422c obo:CHEBI_50076c obo:REO_0000280c |
URI | http://purl.obolibrary.org/obo/CHEBI_23528 |
---|---|
Super-classes |
obo:CHEBI_23367c |
URI | http://purl.obolibrary.org/obo/CHEBI_28619 |
---|---|
Super-classes |
obo:CHEBI_23367c |
URI | http://purl.obolibrary.org/obo/CHEBI_33250 |
---|---|
Super-classes |
obo:BFO_0000040c |
URI | http://purl.obolibrary.org/obo/CHEBI_33696 |
---|---|
Super-classes |
obo:CHEBI_33839c |
Sub-classes |
obo:CHEBI_33697c obo:CHEBI_16991c |
URI | http://purl.obolibrary.org/obo/CHEBI_33697 |
---|---|
Super-classes |
obo:CHEBI_33696c |
URI | http://purl.obolibrary.org/obo/CHEBI_33839 |
---|---|
Super-classes |
obo:CHEBI_23367c |
Sub-classes |
obo:CHEBI_33696c obo:CHEBI_16670c |
URI | http://purl.obolibrary.org/obo/CHEBI_4705 |
---|---|
Super-classes |
obo:CHEBI_16991c |
Sub-classes |
obo:OBI_0000406c |
URI | http://purl.obolibrary.org/obo/CHEBI_472552 |
---|---|
Super-classes |
obo:CHEBI_23367c |
URI | http://purl.obolibrary.org/obo/CHEBI_50076 |
---|---|
Super-classes |
obo:CHEBI_23367c |
URI | http://purl.obolibrary.org/obo/CHEBI_53526 |
---|---|
Super-classes |
obo:CHEBI_23367c |
URI | http://purl.obolibrary.org/obo/CHMO_0000087 |
---|---|
Super-classes |
obo:OBI_0002119c |
URI | http://purl.obolibrary.org/obo/CHMO_0000102 |
---|---|
Super-classes |
obo:OBI_0002119c |
URI | http://purl.obolibrary.org/obo/CL_0000000 |
---|---|
Super-classes |
obo:BFO_0000040c |
Sub-classes |
obo:CL_0000842c obo:CL_0000578c |
URI | http://purl.obolibrary.org/obo/CL_0000010 |
---|---|
Super-classes |
(n91afa4cc91624519895f2f4dded8ec52b6c or n91afa4cc91624519895f2f4dded8ec52b7c) obo:CL_0000578c |
URI | http://purl.obolibrary.org/obo/CL_0000236 |
---|---|
Super-classes |
obo:CL_0000542c |
URI | http://purl.obolibrary.org/obo/CL_0000542 |
---|---|
Super-classes |
obo:CL_0000842c |
Sub-classes |
obo:CL_0000236c |
URI | http://purl.obolibrary.org/obo/CL_0000578 |
---|---|
Super-classes |
obo:OBI_0000047c obo:CL_0000000c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000094c |
Sub-classes |
obo:CL_0000010c |
URI | http://purl.obolibrary.org/obo/CL_0000842 |
---|---|
Super-classes |
obo:CL_0000000c |
Sub-classes |
obo:CL_0000542c |
URI | http://purl.obolibrary.org/obo/ECO_0000000 |
---|---|
Sub-classes |
obo:ECO_0000352c obo:ECO_0007672c obo:ECO_0006151c obo:ECO_0000212c obo:ECO_0006055c obo:ECO_0000501c obo:ECO_0000088c obo:ECO_0000006c obo:ECO_0000361c obo:ECO_0000041c |
In domain of |
obo:ECO_9000000op |
URI | http://purl.obolibrary.org/obo/ECO_0000001 |
---|---|
Super-classes |
obo:ECO_0000205c |
Sub-classes |
obo:ECO_0007323c obo:ECO_0000306c |
URI | http://purl.obolibrary.org/obo/ECO_0000003 |
---|---|
Super-classes |
obo:ECO_0000002c |
Sub-classes |
obo:ECO_0007722c obo:ECO_0007803c obo:ECO_0000150c |
URI | http://purl.obolibrary.org/obo/ECO_0000004 |
---|---|
Description |
If using this term for Gene Ontology annotation, it would be used most typically for annotations to the cellular component ontology. |
Super-classes |
obo:ECO_0000100c |
Sub-classes |
obo:ECO_0007552c obo:ECO_0006042c |
URI | http://purl.obolibrary.org/obo/ECO_0000005 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b22c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b16c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b22c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b16c) obo:IAO_0000136op some obo:GO_0003824c |
Sub-classes |
obo:ECO_0007468c obo:ECO_0000184c obo:ECO_0001129c obo:ECO_0005801c obo:ECO_0001558c |
URI | http://purl.obolibrary.org/obo/ECO_0000006 |
---|---|
Super-classes |
obo:ECO_0000000c obo:IAO_0000030c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b28c) obo:IAO_0000136op some obo:BFO_0000015c |
Sub-classes |
obo:ECO_0000179c obo:ECO_0000008c obo:ECO_0000269c obo:ECO_0000059c obo:ECO_0001094c obo:ECO_0000002c obo:ECO_0005606c obo:ECO_0001592c obo:ECO_0000325c obo:ECO_0000340c obo:ECO_0005516c obo:ECO_0000360c obo:ECO_0000232c obo:ECO_0005504c obo:ECO_0000180c obo:ECO_0007297c obo:ECO_0001830c obo:ECO_0006252c obo:ECO_0005031c obo:ECO_0000220c |
URI | http://purl.obolibrary.org/obo/ECO_0000007 |
---|---|
Super-classes |
obo:ECO_0005517c |
Sub-classes |
obo:ECO_0005804c obo:ECO_0007497c obo:ECO_0005600c obo:ECO_0005599c |
URI | http://purl.obolibrary.org/obo/ECO_0000008 |
---|---|
Description |
Use this evidence type when the annotation is inferred from the timing or location of expression of a gene. It may be difficult to determine whether the expression pattern truly indicates that a gene plays a role in a given process. |
Super-classes |
obo:ECO_0000006c |
Sub-classes |
obo:ECO_0000009c obo:ECO_0000049c obo:ECO_0007006c obo:ECO_0007298c obo:ECO_0000270c obo:ECO_0001836c obo:ECO_0007087c obo:ECO_0000010c |
URI | http://purl.obolibrary.org/obo/ECO_0000009 |
---|---|
Super-classes |
obo:ECO_0000008c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000424c obo:IAO_0000136op some obo:GO_0010467c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b36c) |
Sub-classes |
obo:ECO_0000047c obo:ECO_0000309c obo:ECO_0000310c obo:ECO_0001819c obo:ECO_0000058c obo:ECO_0007303c obo:ECO_0000116c obo:ECO_0000118c obo:ECO_0000358c obo:ECO_0000106c obo:ECO_0000359c obo:ECO_0000291c obo:ECO_0000295c |
URI | http://purl.obolibrary.org/obo/ECO_0000010 |
---|---|
Super-classes |
obo:ECO_0000008c |
Sub-classes |
obo:ECO_0007309c obo:ECO_0000284c obo:ECO_0000112c obo:ECO_0000154c obo:ECO_0000045c obo:ECO_0000114c |
URI | http://purl.obolibrary.org/obo/ECO_0000011 |
---|---|
Super-classes |
obo:ECO_0000059c |
Sub-classes |
obo:ECO_0007326c obo:ECO_0007002c obo:ECO_0000012c obo:ECO_0000056c obo:ECO_0000316c obo:ECO_0000052c |
URI | http://purl.obolibrary.org/obo/ECO_0000012 |
---|---|
Super-classes |
obo:ECO_0000011c |
Sub-classes |
obo:ECO_0000013c obo:ECO_0000038c obo:ECO_0006091c obo:ECO_0000064c obo:ECO_0007578c |
URI | http://purl.obolibrary.org/obo/ECO_0000013 |
---|---|
Super-classes |
obo:ECO_0000012c |
Sub-classes |
obo:ECO_0007579c obo:ECO_0006092c |
URI | http://purl.obolibrary.org/obo/ECO_0000015 |
---|---|
Description |
The allele that encodes the phenotype most common in a particular natural population is referred to as the wild type allele, while any other form of that allele is known as the mutant form. |
Super-classes |
obo:ECO_0000059c |
Sub-classes |
obo:ECO_0000174c obo:ECO_0001113c obo:ECO_0001038c obo:ECO_0001042c obo:ECO_0000016c obo:ECO_0005027c obo:ECO_0000019c obo:ECO_0005512c obo:ECO_0005529c obo:ECO_0006098c obo:ECO_0007325c obo:ECO_0005509c obo:ECO_0005515c obo:ECO_0005514c obo:ECO_0006100c obo:ECO_0005528c obo:ECO_0000054c obo:ECO_0001024c obo:ECO_0000292c obo:ECO_0007000c obo:ECO_0000018c obo:ECO_0000176c obo:ECO_0000042c obo:ECO_0000315c obo:ECO_0005513c |
URI | http://purl.obolibrary.org/obo/ECO_0000016 |
---|---|
Super-classes |
obo:ECO_0000015c |
Sub-classes |
obo:ECO_0007193c obo:ECO_0007089c |
URI | http://purl.obolibrary.org/obo/ECO_0000017 |
---|---|
Super-classes |
obo:ECO_0000059c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b42c) |
Sub-classes |
obo:ECO_0006001c obo:ECO_0007473c obo:ECO_0001273c |
URI | http://purl.obolibrary.org/obo/ECO_0000018 |
---|---|
Super-classes |
obo:ECO_0000015c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001672c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b49c) obo:IAO_0000136op some obo:GO_0009300c |
Sub-classes |
obo:ECO_0006050c obo:ECO_0007556c obo:ECO_0001583c |
URI | http://purl.obolibrary.org/obo/ECO_0000019 |
---|---|
Super-classes |
obo:ECO_0000015c |
Restrictions |
obo:IAO_0000136op some obo:GO_0070549c obo:OBI_0000312op some obo:OBI_0001672c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b57c) |
Sub-classes |
obo:ECO_0007558c obo:ECO_0006052c |
URI | http://purl.obolibrary.org/obo/ECO_0000020 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:IAO_0000136op some obo:GO_0048519c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b64c) |
Sub-classes |
obo:ECO_0000184c obo:ECO_0007707c obo:ECO_0007785c obo:ECO_0000341c |
URI | http://purl.obolibrary.org/obo/ECO_0000021 |
---|---|
Description |
Molecules interacted with might include protein, nucleic acid, ion, or complex. |
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:IAO_0000136op some obo:GO_0005488c obo:OBI_0000312op some obo:OBI_0001146c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b72c) |
Sub-classes |
obo:ECO_0006274c obo:ECO_0000076c obo:ECO_0001092c obo:ECO_0000096c obo:ECO_0007332c obo:ECO_0000293c obo:ECO_0001093c obo:ECO_0001028c obo:ECO_0006273c obo:ECO_0006256c obo:ECO_0000023c obo:ECO_0001046c obo:ECO_0006261c obo:ECO_0000353c obo:ECO_0001127c obo:ECO_0006248c obo:ECO_0000022c |
URI | http://purl.obolibrary.org/obo/ECO_0000022 |
---|---|
Super-classes |
obo:ECO_0000021c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b78c) |
Sub-classes |
obo:ECO_0006074c obo:ECO_0007567c |
URI | http://purl.obolibrary.org/obo/ECO_0000023 |
---|---|
Super-classes |
obo:ECO_0000021c |
Sub-classes |
obo:ECO_0000136c obo:ECO_0000024c obo:ECO_0001824c obo:ECO_0001825c obo:ECO_0001110c obo:ECO_0000040c obo:ECO_0006264c obo:ECO_0006075c obo:ECO_0001045c obo:ECO_0007384c obo:ECO_0000079c |
URI | http://purl.obolibrary.org/obo/ECO_0000024 |
---|---|
Super-classes |
obo:ECO_0000023c |
Sub-classes |
obo:ECO_0006270c obo:ECO_0007008c obo:ECO_0001108c obo:ECO_0007373c obo:ECO_0000025c obo:ECO_0001601c obo:ECO_0000142c obo:ECO_0006076c obo:ECO_0001112c obo:ECO_0001033c obo:ECO_0000085c |
URI | http://purl.obolibrary.org/obo/ECO_0000025 |
---|---|
Description |
Typically enzymes which confer resistance to antibiotics, such as Dihydrofolate reductase or Beta-lactamase, or proteins that give colorimetric or fluorescent signals are used. The Bait protein is generally the protein under study and the methods are readily adaptable to highthroughput mode. |
Super-classes |
obo:ECO_0000024c |
Sub-classes |
obo:ECO_0001817c obo:ECO_0007432c obo:ECO_0001095c obo:ECO_0006077c obo:ECO_0000066c obo:ECO_0007073c obo:ECO_0000294c obo:ECO_0000068c |
URI | http://purl.obolibrary.org/obo/ECO_0000026 |
---|---|
Description |
This term has been made obsolete with the clean up of experimental genomic evidence branch. |
URI | http://purl.obolibrary.org/obo/ECO_0000027 |
---|---|
Description |
For GO annotation, in the case of a single gene, an accession for the related gene's sequence is entered in the evidence_with field. |
Super-classes |
obo:ECO_0000057c |
Sub-classes |
obo:ECO_0007090c obo:ECO_0007194c |
URI | http://purl.obolibrary.org/obo/ECO_0000028 |
---|---|
Super-classes |
obo:ECO_0000202c |
Sub-classes |
obo:ECO_0005536c obo:ECO_0005532c obo:ECO_0000083c obo:ECO_0000081c obo:ECO_0005505c obo:ECO_0000257c obo:ECO_0005534c obo:ECO_0000258c |
URI | http://purl.obolibrary.org/obo/ECO_0000029 |
---|---|
Super-classes |
obo:ECO_0000202c |
Sub-classes |
obo:ECO_0000260c obo:ECO_0000259c |
URI | http://purl.obolibrary.org/obo/ECO_0000030 |
---|---|
Super-classes |
obo:ECO_0000206c obo:ECO_0005560c |
Sub-classes |
obo:ECO_0000032c obo:ECO_0000031c |
URI | http://purl.obolibrary.org/obo/ECO_0000031 |
---|---|
Super-classes |
obo:ECO_0000208c obo:ECO_0000030c |
URI | http://purl.obolibrary.org/obo/ECO_0000032 |
---|---|
Super-classes |
obo:ECO_0000207c obo:ECO_0000030c |
URI | http://purl.obolibrary.org/obo/ECO_0000033 |
---|---|
Super-classes |
obo:ECO_0000204c |
Sub-classes |
obo:ECO_0007321c obo:ECO_0006016c obo:ECO_0000304c |
URI | http://purl.obolibrary.org/obo/ECO_0000034 |
---|---|
Super-classes |
obo:ECO_0000204c |
Sub-classes |
obo:ECO_0000303c obo:ECO_0007320c |
URI | http://purl.obolibrary.org/obo/ECO_0000035 |
---|---|
Description |
An assertion of "no evidence data found" carries the assumption that a more-or-less exhaustive search has been conducted. |
Super-classes |
obo:ECO_0000205c |
Sub-classes |
obo:ECO_0007324c obo:ECO_0000307c |
URI | http://purl.obolibrary.org/obo/ECO_0000037 |
---|---|
Description |
The evidence not_recorded appears in some legacy annotations; it should not be used for new annotations. |
URI | http://purl.obolibrary.org/obo/ECO_0000038 |
---|---|
Super-classes |
obo:ECO_0000012c |
Sub-classes |
obo:ECO_0007580c obo:ECO_0006093c |
URI | http://purl.obolibrary.org/obo/ECO_0000040 |
---|---|
Super-classes |
obo:ECO_0000023c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000443c obo:IAO_0000136op some obo:GO_0003823c |
Sub-classes |
obo:ECO_0007348c obo:ECO_0007033c obo:ECO_0001013c obo:ECO_0006078c obo:ECO_0001015c obo:ECO_0001054c obo:ECO_0007019c obo:ECO_0001014c obo:ECO_0007031c |
URI | http://purl.obolibrary.org/obo/ECO_0000041 |
---|---|
Super-classes |
obo:ECO_0000000c |
Sub-classes |
obo:ECO_0000080c obo:ECO_0000252c obo:ECO_0000044c obo:ECO_0000051c obo:ECO_0000251c obo:ECO_0000057c obo:ECO_0000177c |
URI | http://purl.obolibrary.org/obo/ECO_0000042 |
---|---|
Super-classes |
obo:ECO_0000015c |
Sub-classes |
obo:ECO_0007196c obo:ECO_0007092c |
URI | http://purl.obolibrary.org/obo/ECO_0000044 |
---|---|
Description |
A sequence similarity analysis may involve a gene or a gene product, and it could be based on similarity to a single other gene or to a group of other genes. |
Super-classes |
obo:ECO_0000041c obo:ECO_0007672c |
Sub-classes |
obo:ECO_0000249c obo:ECO_0000202c obo:ECO_0000250c obo:ECO_0000200c obo:ECO_0000201c |
URI | http://purl.obolibrary.org/obo/ECO_0000045 |
---|---|
Super-classes |
obo:ECO_0000010c |
Sub-classes |
obo:ECO_0000283c obo:ECO_0007312c |
URI | http://purl.obolibrary.org/obo/ECO_0000047 |
---|---|
Super-classes |
obo:ECO_0000009c |
Sub-classes |
obo:ECO_0000289c obo:ECO_0007317c |
URI | http://purl.obolibrary.org/obo/ECO_0000049 |
---|---|
Super-classes |
obo:ECO_0000008c |
Restrictions |
obo:IAO_0000136op some obo:GO_0010467c obo:OBI_0000312op some obo:OBI_0002082c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b99c) |
Sub-classes |
obo:ECO_0007765c obo:ECO_0001805c obo:ECO_0001804c obo:ECO_0007682c obo:ECO_0001802c obo:ECO_0001829c obo:ECO_0001801c obo:ECO_0006001c obo:ECO_0005537c obo:ECO_0006238c obo:ECO_0001803c obo:ECO_0001816c |
URI | http://purl.obolibrary.org/obo/ECO_0000050 |
---|---|
Super-classes |
obo:ECO_0000059c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b109c) |
Sub-classes |
obo:ECO_0007197c obo:ECO_0007093c |
URI | http://purl.obolibrary.org/obo/ECO_0000051 |
---|---|
Description |
A genetic similarity analysis might consider genetic markers, polymorphisms, alleles, or other characteristics sometimes considered as part of the field of traditional genetics. Although an attempt has been made to treat as distinct the concepts of "genetic", "genotypic", "genomic", and "sequence", there is considerable overlap in usage throughout the field of biology. |
Super-classes |
obo:ECO_0000041c |
Sub-classes |
obo:ECO_0000254c obo:ECO_0000253c |
URI | http://purl.obolibrary.org/obo/ECO_0000052 |
---|---|
Super-classes |
obo:ECO_0000011c |
Sub-classes |
obo:ECO_0006094c obo:ECO_0007581c |
URI | http://purl.obolibrary.org/obo/ECO_0000053 |
---|---|
Description |
Combinatorial analyses could include experimental or computational results. Examples include: (i) large-scale experiment such as a genome-wide two-hybrid or genome-wide synthetic interactions; (ii) integration of large-scale data sets of various types; and (iii) text-based-computation, e.g. text-mining. For simple sequence comparisons, one should use the sequence similarity analysis evidence type. For microarray results alone, expression pattern analysis is appropriate; whereas, large-scale computational analysis should be used when microarray results are combined with the results of other types of large-scale experiments. |
Super-classes |
obo:ECO_0007673c obo:ECO_0000213c |
Sub-classes |
obo:ECO_0007660c obo:ECO_0007653c obo:ECO_0007667c |
URI | http://purl.obolibrary.org/obo/ECO_0000054 |
---|---|
Super-classes |
obo:ECO_0000015c |
Sub-classes |
obo:ECO_0006095c obo:ECO_0007582c |
URI | http://purl.obolibrary.org/obo/ECO_0000055 |
---|---|
Description |
This general 'array experiment' term should not be used - replace with the specific type of array (e.g. ECO:0000097, ECO:0000062, ECO:0000104, etc.) |
URI | http://purl.obolibrary.org/obo/ECO_0000056 |
---|---|
Description |
Epistasis' can be used in different contexts in different areas of genetics. It is sometimes used to mean 'genetic interaction', whereas other times it may be specific to mutations that block the effects of other mutations. |
Super-classes |
obo:ECO_0000011c |
Sub-classes |
obo:ECO_0007583c obo:ECO_0006096c |
URI | http://purl.obolibrary.org/obo/ECO_0000057 |
---|---|
Description |
Phenotype is defined as the outcome of the expression of a genotype in a given environment. A comparison might involve whole organisms or sub-parts of organisms. |
Super-classes |
obo:ECO_0000041c |
Sub-classes |
obo:ECO_0000067c obo:ECO_0000075c obo:ECO_0000027c obo:ECO_0000060c obo:ECO_0007824c obo:ECO_0000063c obo:ECO_0007748c obo:ECO_0000071c |
URI | http://purl.obolibrary.org/obo/ECO_0000058 |
---|---|
Super-classes |
obo:ECO_0000009c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b120c) obo:OBI_0000312op some obo:OBI_0001463c |
Sub-classes |
obo:ECO_0000275c obo:ECO_0007301c obo:ECO_0000062c obo:ECO_0000104c obo:ECO_0000097c |
URI | http://purl.obolibrary.org/obo/ECO_0000059 |
---|---|
Description |
Observable characteristic traits can be morphology, development, behavior, biochemical or physiological properties, etc. |
Super-classes |
obo:ECO_0000006c |
Restrictions |
obo:IAO_0000136op some obo:GO_0010467c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b128c) obo:OBI_0000312op some obo:OBI_0000966c |
Sub-classes |
obo:ECO_0000017c obo:ECO_0006053c obo:ECO_0000050c obo:ECO_0001032c obo:ECO_0001103c obo:ECO_0001128c obo:ECO_0005675c obo:ECO_0000015c obo:ECO_0005673c obo:ECO_0000172c obo:ECO_0000241c obo:ECO_0007634c obo:ECO_0001012c obo:ECO_0007077c obo:ECO_0005511c obo:ECO_0000298c obo:ECO_0007635c obo:ECO_0000011c obo:ECO_0007075c obo:ECO_0006032c obo:ECO_0000061c obo:ECO_0000240c |
URI | http://purl.obolibrary.org/obo/ECO_0000060 |
---|---|
Super-classes |
obo:ECO_0000057c |
Sub-classes |
obo:ECO_0007094c obo:ECO_0007198c |
URI | http://purl.obolibrary.org/obo/ECO_0000061 |
---|---|
Super-classes |
obo:ECO_0000059c |
Sub-classes |
obo:ECO_0007095c obo:ECO_0007199c |
URI | http://purl.obolibrary.org/obo/ECO_0000062 |
---|---|
Super-classes |
obo:ECO_0000058c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0001463c and n91afa4cc91624519895f2f4dded8ec52b134c) |
Sub-classes |
obo:ECO_0000276c obo:ECO_0007300c obo:ECO_0000101c |
URI | http://purl.obolibrary.org/obo/ECO_0000063 |
---|---|
Super-classes |
obo:ECO_0000057c |
Sub-classes |
obo:ECO_0007200c obo:ECO_0007096c |
URI | http://purl.obolibrary.org/obo/ECO_0000064 |
---|---|
Super-classes |
obo:ECO_0000012c |
Sub-classes |
obo:ECO_0006097c obo:ECO_0007584c |
URI | http://purl.obolibrary.org/obo/ECO_0000066 |
---|---|
Description |
The assay involves screening a library of candidate proteins for the ability bind to a target, cis-regulatory element or any other short, DNA binding sequence placed 5' to a yeast reporter gene (TAIR:TED). |
Super-classes |
obo:ECO_0000025c |
Restrictions |
obo:IAO_0000136op some obo:GO_0043565c obo:OBI_0000312op some obo:OBI_0001681c |
Sub-classes |
obo:ECO_0007568c obo:ECO_0006079c |
URI | http://purl.obolibrary.org/obo/ECO_0000067 |
---|---|
Super-classes |
obo:ECO_0000057c |
Sub-classes |
obo:ECO_0007097c obo:ECO_0007201c |
URI | http://purl.obolibrary.org/obo/ECO_0000068 |
---|---|
Super-classes |
obo:ECO_0000025c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001679c obo:IAO_0000136op some obo:GO_0019904c |
Sub-classes |
obo:ECO_0007531c obo:ECO_0005805c |
URI | http://purl.obolibrary.org/obo/ECO_0000069 |
---|---|
Description |
Color is indicative of methylation status - be it hypo- (pseudo-green), hyper- (pseudo-red), or equal methylation (pseudo-yellow). |
Super-classes |
obo:ECO_0001065c |
Restrictions |
obo:IAO_0000136op some obo:GO_0044030c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b145c) obo:OBI_0000312op some obo:OBI_0001861c |
Sub-classes |
obo:ECO_0000274c obo:ECO_0007302c |
URI | http://purl.obolibrary.org/obo/ECO_0000070 |
---|---|
Description |
If performing GO annotation, the interacting protein is referenced in the evidence_with column. |
Super-classes |
obo:ECO_0000085c |
Sub-classes |
obo:ECO_0006030c obo:ECO_0007546c |
URI | http://purl.obolibrary.org/obo/ECO_0000071 |
---|---|
Super-classes |
obo:ECO_0000057c |
Sub-classes |
obo:ECO_0007202c obo:ECO_0007098c |
URI | http://purl.obolibrary.org/obo/ECO_0000073 |
---|---|
Description |
This term has been made obsolete with the clean up of experimental genomic evidence branch. |
URI | http://purl.obolibrary.org/obo/ECO_0000074 |
---|---|
Description |
The bait protein is fused to the C-terminal ubiquitin (Cub) domain followed by a reporter protein, and the prey protein is fused to a mutated N terminal ubiquitin (NubG) domain. If bait and prey interact, their interaction brings the NubG and Cub domains close enough to reconstitute.TAIR:TED |
Super-classes |
obo:ECO_0006256c |
Restrictions |
obo:IAO_0000136op some obo:GO_0019904c obo:OBI_0000312op some obo:OBI_0001668c |
Sub-classes |
obo:ECO_0006080c obo:ECO_0007569c |
URI | http://purl.obolibrary.org/obo/ECO_0000075 |
---|---|
Super-classes |
obo:ECO_0000057c |
Sub-classes |
obo:ECO_0007203c obo:ECO_0007099c |
URI | http://purl.obolibrary.org/obo/ECO_0000076 |
---|---|
Description |
The interacting protein is referenced in the evidence_with column. |
Super-classes |
obo:ECO_0000021c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001669c |
Sub-classes |
obo:ECO_0007570c obo:ECO_0006081c |
URI | http://purl.obolibrary.org/obo/ECO_0000077 |
---|---|
Description |
The product is the amplification of existing sequences - i.e. more DNA that can be further processed e.g. sequenced, DNA fingerprinting. |
Super-classes |
obo:ECO_0001065c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001684c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b156c) obo:IAO_0000136op some obo:GO_0006306c |
Sub-classes |
obo:ECO_0007204c obo:ECO_0007100c |
URI | http://purl.obolibrary.org/obo/ECO_0000078 |
---|---|
Description |
The DNA fragments are prepared through gel electrophoresis then transferred to a filter membrane. |
Super-classes |
obo:ECO_0005519c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b167c) obo:OBI_0000312op some obo:OBI_0000892c |
Sub-classes |
obo:ECO_0007101c obo:ECO_0007205c |
URI | http://purl.obolibrary.org/obo/ECO_0000079 |
---|---|
Description |
"Used when an annotation is made based on affinity chromatography, which is a selective separation technique by which a compound (e.g., an antibody) is immobilized on a polymeric matrix and used to bind selectively other compounds. Following removal of the unattached components, the bound compound is displaced by changing the concentration of protons, salts, or cofactors in the eluent" (from original definition by TAIR:TED). Types of highly specific interaction might include those of antigen and antibody, enzyme and substrate, or receptor and ligand. |
Super-classes |
obo:ECO_0000023c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b174c) obo:OBI_0000312op some obo:OBI_0001630c |
Sub-classes |
obo:ECO_0006082c obo:ECO_0007571c |
URI | http://purl.obolibrary.org/obo/ECO_0000080 |
---|---|
Super-classes |
obo:ECO_0000041c |
Sub-classes |
obo:ECO_0007826c obo:ECO_0007750c obo:ECO_0000216c obo:ECO_0000215c obo:ECO_0000355c obo:ECO_0000308c obo:ECO_0000214c |
URI | http://purl.obolibrary.org/obo/ECO_0000081 |
---|---|
Super-classes |
obo:ECO_0000028c |
Sub-classes |
obo:ECO_0000262c obo:ECO_0000261c |
URI | http://purl.obolibrary.org/obo/ECO_0000082 |
---|---|
Description |
This term has been made obsolete because PCR is not evidence. The children have been appropriately placed under other parents. |
URI | http://purl.obolibrary.org/obo/ECO_0000083 |
---|---|
Super-classes |
obo:ECO_0000028c |
Sub-classes |
obo:ECO_0000263c obo:ECO_0000264c |
URI | http://purl.obolibrary.org/obo/ECO_0000084 |
---|---|
Description |
Genomic cluster analyses include synteny and operon structure. |
Super-classes |
obo:ECO_0000177c |
Sub-classes |
obo:ECO_0007333c obo:ECO_0000354c |
URI | http://purl.obolibrary.org/obo/ECO_0000085 |
---|---|
Description |
Transcription factors isolated in this way can be incubated with a radiolabeled probe to demonstrate binding. |
Super-classes |
obo:ECO_0000024c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b185c) obo:OBI_0000312op some obo:OBI_0001700c obo:IAO_0000136op some obo:GO_0003823c |
Sub-classes |
obo:ECO_0005644c obo:ECO_0007503c obo:ECO_0000070c obo:ECO_0000226c |
URI | http://purl.obolibrary.org/obo/ECO_0000086 |
---|---|
Description |
The bands can be individually isolated and characterized which leads to the identification of hypo- and hypermethylation events. |
Super-classes |
obo:ECO_0001065c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001685c obo:IAO_0000136op some obo:GO_0006306c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b192c) |
Sub-classes |
obo:ECO_0007102c obo:ECO_0007206c |
URI | http://purl.obolibrary.org/obo/ECO_0000087 |
---|---|
Super-classes |
obo:ECO_0005593c obo:ECO_0001098c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b203c and obo:OBI_0000185c and obo:OBI_0001632c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b203c and obo:OBI_0000185c and obo:OBI_0001632c) obo:IAO_0000136op some obo:GO_0033036c |
Sub-classes |
obo:ECO_0005594c obo:ECO_0007486c obo:ECO_0006031c obo:ECO_0000092c obo:ECO_0000300c obo:ECO_0000090c obo:ECO_0000301c |
URI | http://purl.obolibrary.org/obo/ECO_0000088 |
---|---|
Description |
The biological system in question might be a multi-step process or pathway or a physical complex comprising several components. The components in the experimental evidence can come from the same species or a mix of species. The experimental evidences may be only partial or weak. |
Super-classes |
obo:ECO_0000000c |
Sub-classes |
obo:ECO_0007746c obo:ECO_0005551c obo:ECO_0007827c obo:ECO_0005548c obo:ECO_0005549c |
URI | http://purl.obolibrary.org/obo/ECO_0000089 |
---|---|
Super-classes |
obo:ECO_0005519c |
Sub-classes |
obo:ECO_0007470c obo:ECO_0001270c |
URI | http://purl.obolibrary.org/obo/ECO_0000090 |
---|---|
Super-classes |
obo:ECO_0000087c |
Sub-classes |
obo:ECO_0005591c obo:ECO_0005579c obo:ECO_0007485c |
URI | http://purl.obolibrary.org/obo/ECO_0000092 |
---|---|
Super-classes |
obo:ECO_0000087c |
Sub-classes |
obo:ECO_0007103c obo:ECO_0007207c |
URI | http://purl.obolibrary.org/obo/ECO_0000093 |
---|---|
Super-classes |
obo:ECO_0005519c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0001985c and n91afa4cc91624519895f2f4dded8ec52b217c) |
Sub-classes |
obo:ECO_0000278c obo:ECO_0007305c |
URI | http://purl.obolibrary.org/obo/ECO_0000094 |
---|---|
Description |
The children of 'biological assay evidence' have been moved under 'direct assay evidence', and this term has been deprecated with no children left. |
URI | http://purl.obolibrary.org/obo/ECO_0000095 |
---|---|
Description |
Cell growth aspects can include growth rate and extent of growth. A cell growth curve acts as a natural reporter. |
Super-classes |
obo:ECO_0001563c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000964c |
Sub-classes |
obo:ECO_0005639c obo:ECO_0005638c |
URI | http://purl.obolibrary.org/obo/ECO_0000096 |
---|---|
Description |
EMSA is often used for assessing TF-binding with fluorophore labelling. Protein-nucleic acid complexes generally migrate at a slower rate than the corresponding non-bonded nucleic acid. |
Super-classes |
obo:ECO_0000021c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001671c |
Sub-classes |
obo:ECO_0007474c obo:ECO_0001807c |
URI | http://purl.obolibrary.org/obo/ECO_0000097 |
---|---|
Super-classes |
obo:ECO_0000058c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0001463c and n91afa4cc91624519895f2f4dded8ec52b224c) |
Sub-classes |
obo:ECO_0000273c obo:ECO_0005630c obo:ECO_0000105c |
URI | http://purl.obolibrary.org/obo/ECO_0000098 |
---|---|
Description |
This term has been made obsolete with the clean up of experimental genomic evidence branch. |
URI | http://purl.obolibrary.org/obo/ECO_0000100 |
---|---|
Super-classes |
obo:ECO_0000002c |
Sub-classes |
obo:ECO_0007534c obo:ECO_0000102c obo:ECO_0000156c obo:ECO_0006005c obo:ECO_0000004c |
URI | http://purl.obolibrary.org/obo/ECO_0000101 |
---|---|
Super-classes |
obo:ECO_0000062c |
Sub-classes |
obo:ECO_0000272c obo:ECO_0007299c |
URI | http://purl.obolibrary.org/obo/ECO_0000102 |
---|---|
Super-classes |
obo:ECO_0000100c |
Sub-classes |
obo:ECO_0007104c obo:ECO_0007208c |
URI | http://purl.obolibrary.org/obo/ECO_0000104 |
---|---|
Description |
REM is a 'reverse-format' microarray, where the unknown sample is immoblized to a surface and known DNA is hybridized to that. |
Super-classes |
obo:ECO_0000058c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0001463c and n91afa4cc91624519895f2f4dded8ec52b229c) |
Sub-classes |
obo:ECO_0007313c obo:ECO_0000285c |
URI | http://purl.obolibrary.org/obo/ECO_0000105 |
---|---|
Super-classes |
obo:ECO_0000097c |
Sub-classes |
obo:ECO_0000277c obo:ECO_0007304c |
URI | http://purl.obolibrary.org/obo/ECO_0000106 |
---|---|
Super-classes |
obo:ECO_0000009c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000860c |
Sub-classes |
obo:ECO_0005653c obo:ECO_0007518c |
URI | http://purl.obolibrary.org/obo/ECO_0000109 |
---|---|
Description |
The starting product for PCR, and therefore amplification volume, is directly correlated to the transcription rate. |
Super-classes |
obo:ECO_0005518c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b236c) obo:OBI_0000312op some obo:OBI_0001361c |
Sub-classes |
obo:ECO_0007475c obo:ECO_0001566c obo:ECO_0001808c |
URI | http://purl.obolibrary.org/obo/ECO_0000110 |
---|---|
Super-classes |
obo:ECO_0001106c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b242c) |
Sub-classes |
obo:ECO_0007315c obo:ECO_0000288c |
URI | http://purl.obolibrary.org/obo/ECO_0000112 |
---|---|
Description |
Western blot is used for protein detection and analysis. A mixed protein sample is separated through polyacrylamide gel electrophoresis then transferred to a membrane, such as polyvinylidene fluoride (PVDF), and labeled with protein-specific antibodies. |
Super-classes |
obo:ECO_0005593c obo:ECO_0000010c obo:ECO_0000333c |
Sub-classes |
obo:ECO_0007306c obo:ECO_0000279c obo:ECO_0006169c |
URI | http://purl.obolibrary.org/obo/ECO_0000114 |
---|---|
Super-classes |
obo:ECO_0000010c |
Sub-classes |
obo:ECO_0007310c obo:ECO_0000281c |
URI | http://purl.obolibrary.org/obo/ECO_0000116 |
---|---|
Description |
Differential hybridization identifies differentially expressed cloned genes. Two different mRNA-derived probes are used to demonstrate RNA expression under a specific condition. |
Super-classes |
obo:ECO_0000009c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b251c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b256c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b251c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b256c) |
Sub-classes |
obo:ECO_0000287c obo:ECO_0007314c |
URI | http://purl.obolibrary.org/obo/ECO_0000118 |
---|---|
Description |
Subtractive hybridization is used for isolation and identification of transcripts involving the removal of any sequences present in the control from the test probe to detect only transcripts present in the sample. The method is PCR-based for the comparison of two cDNA libraries. |
Super-classes |
obo:ECO_0000009c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b266c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b271c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b266c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b271c) |
Sub-classes |
obo:ECO_0007318c obo:ECO_0000290c |
URI | http://purl.obolibrary.org/obo/ECO_0000120 |
---|---|
Super-classes |
obo:ECO_0005027c |
Sub-classes |
obo:ECO_0007562c obo:ECO_0006063c |
URI | http://purl.obolibrary.org/obo/ECO_0000122 |
---|---|
Super-classes |
obo:ECO_0001533c |
Sub-classes |
obo:ECO_0007807c obo:ECO_0007725c obo:ECO_0000124c |
URI | http://purl.obolibrary.org/obo/ECO_0000124 |
---|---|
Super-classes |
obo:ECO_0000122c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0002167c obo:IAO_0000136op some obo:GO_0033036c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b283c) |
Sub-classes |
obo:ECO_0007726c obo:ECO_0000132c obo:ECO_0007808c obo:ECO_0000128c obo:ECO_0000130c obo:ECO_0000126c |
URI | http://purl.obolibrary.org/obo/ECO_0000126 |
---|---|
Super-classes |
obo:ECO_0000124c |
Sub-classes |
obo:ECO_0007106c obo:ECO_0007210c |
URI | http://purl.obolibrary.org/obo/ECO_0000128 |
---|---|
Super-classes |
obo:ECO_0000124c |
Sub-classes |
obo:ECO_0007107c obo:ECO_0007211c |
URI | http://purl.obolibrary.org/obo/ECO_0000130 |
---|---|
Super-classes |
obo:ECO_0000124c |
Sub-classes |
obo:ECO_0007212c obo:ECO_0007108c |
URI | http://purl.obolibrary.org/obo/ECO_0000132 |
---|---|
Super-classes |
obo:ECO_0000124c |
Sub-classes |
obo:ECO_0007213c obo:ECO_0007109c |
URI | http://purl.obolibrary.org/obo/ECO_0000134 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:IAO_0000136op some obo:GO_0015031c obo:OBI_0000312op some obo:OBI_0000964c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b291c) |
Sub-classes |
obo:ECO_0007709c obo:ECO_0007035c obo:ECO_0000162c obo:ECO_0007789c |
URI | http://purl.obolibrary.org/obo/ECO_0000136 |
---|---|
Super-classes |
obo:ECO_0000023c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001591c obo:IAO_0000136op some (obo:GO_0005488c and n91afa4cc91624519895f2f4dded8ec52b297c) |
Sub-classes |
obo:ECO_0001601c obo:ECO_0001826c obo:ECO_0001827c obo:ECO_0006083c obo:ECO_0006010c obo:ECO_0001818c obo:ECO_0001815c obo:ECO_0007505c obo:ECO_0001814c obo:ECO_0000138c obo:ECO_0000144c obo:ECO_0000146c obo:ECO_0001810c obo:ECO_0006270c |
URI | http://purl.obolibrary.org/obo/ECO_0000138 |
---|---|
Super-classes |
obo:ECO_0000136c |
Restrictions |
obo:IAO_0000136op some obo:GO_0032549c |
Sub-classes |
obo:ECO_0006084c obo:ECO_0007572c |
URI | http://purl.obolibrary.org/obo/ECO_0000140 |
---|---|
Super-classes |
obo:ECO_0000325c |
Sub-classes |
obo:ECO_0007110c obo:ECO_0007214c |
URI | http://purl.obolibrary.org/obo/ECO_0000142 |
---|---|
Super-classes |
obo:ECO_0000024c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001591c obo:IAO_0000136op some (obo:GO_0005488c and n91afa4cc91624519895f2f4dded8ec52b304c) |
Sub-classes |
obo:ECO_0007573c obo:ECO_0006085c |
URI | http://purl.obolibrary.org/obo/ECO_0000144 |
---|---|
Super-classes |
obo:ECO_0000136c |
Sub-classes |
obo:ECO_0006086c obo:ECO_0007574c |
URI | http://purl.obolibrary.org/obo/ECO_0000146 |
---|---|
Super-classes |
obo:ECO_0000136c |
Sub-classes |
obo:ECO_0007575c obo:ECO_0006087c |
URI | http://purl.obolibrary.org/obo/ECO_0000150 |
---|---|
Super-classes |
obo:ECO_0000003c |
Restrictions |
obo:IAO_0000136op some obo:GO_0034645c obo:OBI_0000312op some obo:OBI_0002622c |
Sub-classes |
obo:ECO_0007723c obo:ECO_0007804c obo:ECO_0000152c |
URI | http://purl.obolibrary.org/obo/ECO_0000152 |
---|---|
Super-classes |
obo:ECO_0000150c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b312c) |
Sub-classes |
obo:ECO_0007215c obo:ECO_0007111c |
URI | http://purl.obolibrary.org/obo/ECO_0000154 |
---|---|
Super-classes |
obo:ECO_0000010c |
Sub-classes |
obo:ECO_0007311c obo:ECO_0000282c |
URI | http://purl.obolibrary.org/obo/ECO_0000156 |
---|---|
Super-classes |
obo:ECO_0000100c |
Sub-classes |
obo:ECO_0000158c obo:ECO_0000160c obo:ECO_0007684c obo:ECO_0007787c |
URI | http://purl.obolibrary.org/obo/ECO_0000158 |
---|---|
Super-classes |
obo:ECO_0000156c |
Sub-classes |
obo:ECO_0007216c obo:ECO_0007112c |
URI | http://purl.obolibrary.org/obo/ECO_0000160 |
---|---|
Super-classes |
obo:ECO_0000156c |
Sub-classes |
obo:ECO_0007217c obo:ECO_0007113c |
URI | http://purl.obolibrary.org/obo/ECO_0000162 |
---|---|
Description |
The transporter is a recombinant protein. |
Super-classes |
obo:ECO_0000134c |
Sub-classes |
obo:ECO_0007218c obo:ECO_0007114c |
URI | http://purl.obolibrary.org/obo/ECO_0000164 |
---|---|
Description |
The scale of electrophysiology assays can range from small, e.g. a single ion channel, to large, e.g. an entire organ such as a heart. |
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b318c) obo:OBI_0000312op some obo:OBI_0002176c |
Sub-classes |
obo:ECO_0006038c obo:ECO_0006012c obo:ECO_0005566c obo:ECO_0006043c obo:ECO_0005571c obo:ECO_0006006c obo:ECO_0005577c obo:ECO_0005564c obo:ECO_0007535c obo:ECO_0005576c obo:ECO_0005570c |
URI | http://purl.obolibrary.org/obo/ECO_0000166 |
---|---|
Super-classes |
obo:ECO_0005576c |
Sub-classes |
obo:ECO_0007115c obo:ECO_0007219c |
URI | http://purl.obolibrary.org/obo/ECO_0000168 |
---|---|
Super-classes |
obo:ECO_0000002c |
Sub-classes |
obo:ECO_0007768c obo:ECO_0001071c obo:ECO_0007693c obo:ECO_0000170c obo:ECO_0001087c |
URI | http://purl.obolibrary.org/obo/ECO_0000170 |
---|---|
Super-classes |
obo:ECO_0000168c |
Restrictions |
obo:IAO_0000136op some obo:GO_0001047c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b325c and obo:OBI_0000424c and obo:OBI_0000913c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b325c and obo:OBI_0000424c and obo:OBI_0000913c) |
Sub-classes |
obo:ECO_0007633c obo:ECO_0007632c |
URI | http://purl.obolibrary.org/obo/ECO_0000172 |
---|---|
Description |
For example, the accumulation of a biosynthetic intermediate. |
Super-classes |
obo:ECO_0000059c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000366c |
Sub-classes |
obo:ECO_0007220c obo:ECO_0007116c |
URI | http://purl.obolibrary.org/obo/ECO_0000174 |
---|---|
Description |
Examples include: abnormal growth of the root in response to gravity, delay in flowering in response to varying light conditions. |
Super-classes |
obo:ECO_0000015c |
Restrictions |
obo:IAO_0000136op some (obo:GO_0050896c and n91afa4cc91624519895f2f4dded8ec52b336c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b345c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b350c) obo:OBI_0000312op some (obo:GO_0050896c and n91afa4cc91624519895f2f4dded8ec52b336c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b345c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b350c) obo:OBI_0000312op some (obo:GO_0050896c and n91afa4cc91624519895f2f4dded8ec52b336c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b345c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b350c) |
Sub-classes |
obo:ECO_0007221c obo:ECO_0007117c |
URI | http://purl.obolibrary.org/obo/ECO_0000176 |
---|---|
Super-classes |
obo:ECO_0000015c |
Sub-classes |
obo:ECO_0007118c obo:ECO_0007222c |
URI | http://purl.obolibrary.org/obo/ECO_0000177 |
---|---|
Description |
This type of evidence might include identity of neighboring genes, operon structure, synteny, phylogenetic analysis, or other whole-genome analysis. |
Super-classes |
obo:ECO_0000041c |
Sub-classes |
obo:ECO_0007327c obo:ECO_0000317c obo:ECO_0000084c |
URI | http://purl.obolibrary.org/obo/ECO_0000178 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b357c) obo:OBI_0000312op some obo:OBI_0000964c |
Sub-classes |
obo:ECO_0007119c obo:ECO_0007223c |
URI | http://purl.obolibrary.org/obo/ECO_0000179 |
---|---|
Super-classes |
obo:ECO_0000006c |
Restrictions |
obo:IAO_0000136op some obo:GO_0008150c obo:OBI_0000312op some obo:OBI_0000966c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b365c) |
Sub-classes |
obo:ECO_0007120c obo:ECO_0007224c |
URI | http://purl.obolibrary.org/obo/ECO_0000180 |
---|---|
Super-classes |
obo:ECO_0000006c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b371c) |
Sub-classes |
obo:ECO_0007121c obo:ECO_0007225c |
URI | http://purl.obolibrary.org/obo/ECO_0000181 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000978c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b378c) |
Sub-classes |
obo:ECO_0007122c obo:ECO_0007226c |
URI | http://purl.obolibrary.org/obo/ECO_0000182 |
---|---|
Description |
Use ECO:0001563 (cell growth assay evidence) in place of this term. |
URI | http://purl.obolibrary.org/obo/ECO_0000183 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:IAO_0000136op some obo:GO_0008152c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b386c) obo:OBI_0000312op some obo:OBI_0000978c |
Sub-classes |
obo:ECO_0006064c obo:ECO_0007563c |
URI | http://purl.obolibrary.org/obo/ECO_0000184 |
---|---|
Super-classes |
obo:ECO_0000020c obo:ECO_0000005c |
Sub-classes |
obo:ECO_0007227c obo:ECO_0007123c |
URI | http://purl.obolibrary.org/obo/ECO_0000200 |
---|---|
Description |
Such alignments may be pairwise alignments or multiple alignments. |
Super-classes |
obo:ECO_0000044c |
Sub-classes |
obo:ECO_0000247c obo:ECO_0005554c obo:ECO_0000326c obo:ECO_0005555c obo:ECO_0000248c obo:ECO_0000345c |
URI | http://purl.obolibrary.org/obo/ECO_0000201 |
---|---|
Description |
Orthology is a relationship between genes in different species indicating that the genes derive from a common ancestor. |
Super-classes |
obo:ECO_0000044c |
Sub-classes |
obo:ECO_0000265c obo:ECO_0000266c |
URI | http://purl.obolibrary.org/obo/ECO_0000202 |
---|---|
Description |
Used when evidence from any kind of statistical model of a sequence or group of sequences is used to make a prediction about the function of a protein or RNA. Examples of relevant evidence are: Hidden Markov Models, PROSITE motifs, and tools such as tRNASCAN. |
Super-classes |
obo:ECO_0000044c |
Sub-classes |
obo:ECO_0000028c obo:ECO_0000029c obo:ECO_0000255c obo:ECO_0005535c obo:ECO_0000256c |
URI | http://purl.obolibrary.org/obo/ECO_0000203 |
---|---|
Description |
An automatic assertion is based on computationally generated information that is not reviewed by a person prior to making the assertion. For example, one common type of automatic assertion involves creating an association of evidence with an entity based on commonness of attributes of that entity and another entity for which an assertion already exists. The commonness is determined algorithmically. |
Super-classes |
obo:ECO_0000217c |
URI | http://purl.obolibrary.org/obo/ECO_0000204 |
---|---|
Super-classes |
obo:ECO_0006151c |
Sub-classes |
obo:ECO_0006185c obo:ECO_0007319c obo:ECO_0000033c obo:ECO_0000034c obo:ECO_0000302c |
URI | http://purl.obolibrary.org/obo/ECO_0000205 |
---|---|
Super-classes |
obo:ECO_0000361c |
Sub-classes |
obo:ECO_0007322c obo:ECO_0006018c obo:ECO_0000001c obo:ECO_0007647c obo:ECO_0000305c obo:ECO_0000035c |
URI | http://purl.obolibrary.org/obo/ECO_0000206 |
---|---|
Super-classes |
obo:ECO_0005554c |
Sub-classes |
obo:ECO_0000207c obo:ECO_0000209c obo:ECO_0000030c obo:ECO_0000208c |
URI | http://purl.obolibrary.org/obo/ECO_0000207 |
---|---|
Super-classes |
obo:ECO_0000206c |
Sub-classes |
obo:ECO_0000032c obo:ECO_0000210c |
URI | http://purl.obolibrary.org/obo/ECO_0000208 |
---|---|
Super-classes |
obo:ECO_0000206c |
Sub-classes |
obo:ECO_0000031c obo:ECO_0000211c |
URI | http://purl.obolibrary.org/obo/ECO_0000209 |
---|---|
Super-classes |
obo:ECO_0000206c obo:ECO_0005561c |
Sub-classes |
obo:ECO_0000211c obo:ECO_0000210c |
URI | http://purl.obolibrary.org/obo/ECO_0000210 |
---|---|
Super-classes |
obo:ECO_0000209c obo:ECO_0000207c |
URI | http://purl.obolibrary.org/obo/ECO_0000211 |
---|---|
Super-classes |
obo:ECO_0000208c obo:ECO_0000209c |
URI | http://purl.obolibrary.org/obo/ECO_0000212 |
---|---|
Description |
A key aspect of this type of evidence is that two or more pieces of information are combined to generate an emergent type of evidence not possible with the constituent pieces of evidence alone. A combinatorial analysis typically involves incorporation of different types of evidence. |
Super-classes |
obo:ECO_0000000c |
Sub-classes |
obo:ECO_0007661c obo:ECO_0007673c obo:ECO_0007677c obo:ECO_0007674c obo:ECO_0007011c obo:ECO_0007012c obo:ECO_0000244c obo:ECO_0000213c obo:ECO_0007654c |
URI | http://purl.obolibrary.org/obo/ECO_0000213 |
---|---|
Description |
Combinatorial analyses could include experimental or computational results. Examples include: (i) large-scale experiment such as a genome-wide two-hybrid or genome-wide synthetic interactions; (ii) integration of large-scale data sets of various types; and (iii) text-based-computation, e.g. text-mining. For simple sequence comparisons, one should use the sequence similarity analysis evidence type. For microarray results alone, expression pattern analysis is appropriate; whereas, large-scale computational analysis should be used when microarray results are combined with the results of other types of large-scale experiments. |
Super-classes |
obo:ECO_0000212c obo:ECO_0000501c |
Sub-classes |
obo:ECO_0000053c obo:ECO_0007829c obo:ECO_0007676c obo:ECO_0007593c obo:ECO_0007830c obo:ECO_0007592c obo:ECO_0007679c |
URI | http://purl.obolibrary.org/obo/ECO_0000214 |
---|---|
Description |
This type of evidence can be used in support of both positive and "not" GO annotations. It should be used to annotate ancestral genes but not extant ones. |
Super-classes |
obo:ECO_0000080c |
Sub-classes |
obo:ECO_0000319c obo:ECO_0007329c |
URI | http://purl.obolibrary.org/obo/ECO_0000215 |
---|---|
Description |
Long branch lengths indicate that descendant sequences may have acquired different or additional functions than the ancestral sequence. |
Super-classes |
obo:ECO_0000080c |
Sub-classes |
obo:ECO_0000321c obo:ECO_0007331c |
URI | http://purl.obolibrary.org/obo/ECO_0000216 |
---|---|
Description |
The loss of certain residues important for function can indicate that a sequence lacks a particular function. |
Super-classes |
obo:ECO_0000080c |
Sub-classes |
obo:ECO_0000320c obo:ECO_0007330c |
URI | http://purl.obolibrary.org/obo/ECO_0000217 |
---|---|
Sub-classes |
obo:ECO_0000218c obo:ECO_0000203c |
In range of |
obo:ECO_9000000op |
URI | http://purl.obolibrary.org/obo/ECO_0000218 |
---|---|
Description |
A manual assertion could be based on evidence that is generated by and interpreted by a human or it could involve human review of computationally generated information. |
Super-classes |
obo:ECO_0000217c |
URI | http://purl.obolibrary.org/obo/ECO_0000219 |
---|---|
Super-classes |
obo:ECO_0000220c |
Sub-classes |
obo:ECO_0007813c obo:ECO_0001820c obo:ECO_0001598c obo:ECO_0000221c obo:ECO_0000225c obo:ECO_0007733c |
URI | http://purl.obolibrary.org/obo/ECO_0000220 |
---|---|
Super-classes |
obo:ECO_0000006c |
Sub-classes |
obo:ECO_0007732c obo:ECO_0007812c obo:ECO_0000219c obo:ECO_0001118c |
URI | http://purl.obolibrary.org/obo/ECO_0000221 |
---|---|
Description |
Typically thousands to millions of reads are produced in parallel. |
Super-classes |
obo:ECO_0000219c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b419c) obo:OBI_0000312op some obo:OBI_0001247c |
Sub-classes |
obo:ECO_0000222c obo:ECO_0000224c obo:ECO_0007734c obo:ECO_0000223c obo:ECO_0007814c |
URI | http://purl.obolibrary.org/obo/ECO_0000222 |
---|---|
Description |
In Illumina sequencing technology, adapters are ligated onto the ends of randomly fragmented DNA. After single-stranded fragments are bound to the inside surface of a flow cell channel, they undergo in-place bridge PCR amplification. To begin the sequencing cycle, labeled reversible terminators, primers and DNA polymerase are added, followed by laser excitation of the fluorescent label and high resolution scanning. After non-incorporated nucleotides are washed away and the dye is chemically removed, the next cycle repeats with four labeled reversible terminators, primers and DNA polymerase, again followed by imaging. |
Super-classes |
obo:ECO_0000221c |
Sub-classes |
obo:ECO_0007229c obo:ECO_0007125c |
URI | http://purl.obolibrary.org/obo/ECO_0000223 |
---|---|
Description |
454 pyrosequencing technology amplifies individual DNA fragments inside water droplets within an oil solution (emulsion PCR). Within each droplet, a single DNA template is attached to a single primer-coated bead. Each bead is subsequently captured in a picolitre well within the sequencing machine. A luciferase-based readout system is used to identify individual nucleotides added to the nascent DNA. The target strand is usually prepared by fragmentation, adaptor ligation, and amplification by emulsion PCR. |
Super-classes |
obo:ECO_0000221c |
Sub-classes |
obo:ECO_0007126c obo:ECO_0007230c |
URI | http://purl.obolibrary.org/obo/ECO_0000224 |
---|---|
Description |
SOLiD sequencing technology is based on sequencing by ligation. After library preparation, emulsion PCR and bead enrichment are performed, including 3' modification of templates on selected beads to allow covalent bonding to a slide. 3' modified beads are attached to a glass slide and primers are added. Four fluorescently labeled di-base probes are added and multiple cycles of ligation, detection and cleavage are performed. The number of cycles determines read length. After a number of ligation cycles, the extension product is removed and another round of ligation cycles is performed with a new primer complimentary to the n-1 position of the template. Five rounds of primer reset are performed for each sequence tag. Samples are prepared by fragmentation of a sample library, adaptor ligation, emulsion PCR, and attachment of resultant beads to glass slides. |
Super-classes |
obo:ECO_0000221c |
Sub-classes |
obo:ECO_0007231c obo:ECO_0007127c |
URI | http://purl.obolibrary.org/obo/ECO_0000225 |
---|---|
Description |
Chain termination sequencing, also called Sanger sequencing after its developer, uses dideoxynucleotide triphosphates (ddNTPs) as DNA chain terminators. Single-stranded DNA template, DNA primer, DNA polymerase, fluorescently or radioactively labeled nucleotides, and one of four ddNTPs are added together in each of four separate sequencing reactions. The synthesized and labeled DNA fragments from each of the four reactions are denatured, separated by size by gel electrophoresis, and visualized by autoradiography or UV light. The ddNTPs lack an OH group so the next dNTP cannot be attached, causing chain termination. |
Super-classes |
obo:ECO_0000219c |
Sub-classes |
obo:ECO_0007128c obo:ECO_0007232c |
URI | http://purl.obolibrary.org/obo/ECO_0000226 |
---|---|
Description |
Chromatin immunoprecipitation (ChIP) is used to investigate protein-DNA interactions in vivo. DNA and proteins are chemically cross-linked in vivo to form chromatin complexes, followed by cell lysis and DNA shearing. Fragmented DNA-protein complexes are selectively enriched for a protein of interest using a specific antibody (immunoprecipitation). Protein digestion and DNA purification are performed prior to DNA detection via molecular cloning and sequencing, polymerase chain reaction (PCR), microarray analysis (ChIP-on-chip), or direct high-throughput sequencing (ChIP-seq). |
Super-classes |
obo:ECO_0000085c |
Restrictions |
obo:IAO_0000136op some obo:GO_0043565c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b427c) obo:OBI_0000312op some obo:OBI_0001956c |
Sub-classes |
obo:ECO_0007786c obo:ECO_0001806c obo:ECO_0007706c obo:ECO_0000228c obo:ECO_0000229c obo:ECO_0000227c obo:ECO_0000230c |
URI | http://purl.obolibrary.org/obo/ECO_0000227 |
---|---|
Description |
ChIP-PCR is often used to validate ChIP-chip results and less frequently,ChIP-Seq results. |
Super-classes |
obo:ECO_0000226c |
Sub-classes |
obo:ECO_0005620c obo:ECO_0007502c |
URI | http://purl.obolibrary.org/obo/ECO_0000228 |
---|---|
Super-classes |
obo:ECO_0000226c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0002169c |
Sub-classes |
obo:ECO_0007129c obo:ECO_0007233c |
URI | http://purl.obolibrary.org/obo/ECO_0000229 |
---|---|
Description |
ChIP-Seq experiments often use the input as a control to eliminate biases. To obtain similar results, ChIP-chip with high-density tiling arrays can be used. |
Super-classes |
obo:ECO_0000226c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000716c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b435c) |
Sub-classes |
obo:ECO_0005621c obo:ECO_0006009c |
URI | http://purl.obolibrary.org/obo/ECO_0000230 |
---|---|
Description |
A fixating agent such as formaldehyde is used to cross link proteins and DNA. Sonication is applied for DNA shearing. For transcription factor tagging, an antibody or epitope is employed. After cross-linking is reversed, the DNA is amplified and labeled with a flourophore for microarray which produces a resolution of aproximately 500 bp. |
Super-classes |
obo:ECO_0000226c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b442c) obo:OBI_0000312op some obo:OBI_0001248c |
Sub-classes |
obo:ECO_0006007c obo:ECO_0005618c |
URI | http://purl.obolibrary.org/obo/ECO_0000231 |
---|---|
Description |
Quantitative PCR enables both detection and quantification (as absolute number of copies or relative amount when normalized to DNA input or additional normalizing genes) of one or more specific sequences in a DNA sample. The dye is activated upon binding double-stranded DNA. Although qRT-PCR is commonly found in literature synonymous to qPCR, it is preferable not to use this synonym as it is the accepted abbreviation for reverse transcription PCR. qPCR should be used instead (ISBN 978-0-470-68386-6 page 173). qPCR can be used to quantitatively determine levels of gene expression. |
Super-classes |
obo:ECO_0005519c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000893c |
Sub-classes |
obo:ECO_0007521c obo:ECO_0005660c |
URI | http://purl.obolibrary.org/obo/ECO_0000232 |
---|---|
Description |
Chromosome conformation capture technologies are used to study the structural properties and spatial organization of chromosomes inside cells. All types of chromosome conformation capture technology involve five primary steps: cross-linking of DNA in vivo, restriction digestion, intramolecular ligation, reversing cross-linkages, and DNA enrichment and quantitation. The last step is different for each type of chromosome conformation capture technology, and may include PCR (3C), inverse PCR (4C), or ligation-mediated amplification (5C). Methods for product quantitation can include agarose gel detection or real-time quantitative PCR in the case of 3C, or high-throughput sequencing or microarray analysis for 4C and 5C. |
Super-classes |
obo:ECO_0000006c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b450c) obo:OBI_0000312op some obo:OBI_0002438c |
Sub-classes |
obo:ECO_0000238c obo:ECO_0000233c obo:ECO_0000235c obo:ECO_0000234c obo:ECO_0007741c obo:ECO_0007822c obo:ECO_0000239c |
URI | http://purl.obolibrary.org/obo/ECO_0000233 |
---|---|
Description |
3C is used to study the structural properties and spatial organization of chromosomes inside cells. Like other types of chromosome conformation capture technology, 3C differs only in the fifth step, which involves performing either standard polymerase chain reaction (PCR) or quantitative PCR (qPCR) for product quantitation. |
Super-classes |
obo:ECO_0000232c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0002439c |
Sub-classes |
obo:ECO_0007823c obo:ECO_0000237c obo:ECO_0007742c |
URI | http://purl.obolibrary.org/obo/ECO_0000234 |
---|---|
Description |
4C is used to study the structural properties and spatial organization of chromosomes inside cells. Like other types of chromosome conformation capture technology, 4C differs only in the fifth step, which involves inverse polymerase chain reaction (inverse PCR) on a circularized 3C library prior to product quantitation. |
Super-classes |
obo:ECO_0000232c |
Sub-classes |
obo:ECO_0007234c obo:ECO_0007130c |
URI | http://purl.obolibrary.org/obo/ECO_0000235 |
---|---|
Description |
5C is used to study the structural properties and spatial organization of chromosomes inside cells. Like other types of chromosome conformation capture technology, 5C differs only in the fifth step, which involves ligation-mediated amplification (LMA) followed by product quantitation. |
Super-classes |
obo:ECO_0000232c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001919c |
Sub-classes |
obo:ECO_0007235c obo:ECO_0007131c |
URI | http://purl.obolibrary.org/obo/ECO_0000236 |
---|---|
Description |
See 3C evidence. 3C evidence was initially developed using PCR. |
URI | http://purl.obolibrary.org/obo/ECO_0000237 |
---|---|
Super-classes |
obo:ECO_0000233c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000893c and obo:OBI_0002439c) |
Sub-classes |
obo:ECO_0007237c obo:ECO_0007133c |
URI | http://purl.obolibrary.org/obo/ECO_0000238 |
---|---|
Description |
Hi-C is used to study the structural properties and spatial organization of chromosomes inside cells. Hi-C is similar to other types of chromosome conformation capture technology, but involves the addition of biotinylated nucleotides during the second or fourth step and enrichment for ligated fragments using immunoprecipitation after the fourth step. |
Super-classes |
obo:ECO_0000232c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0002440c |
Sub-classes |
obo:ECO_0007134c obo:ECO_0007238c |
URI | http://purl.obolibrary.org/obo/ECO_0000239 |
---|---|
Description |
3C-seq is used to study the structural properties and spatial organization of chromosomes inside cells. Like other types of chromosome conformation capture technology, 3C-seq differs only in the fifth step, which involves inverse polymerase chain reaction (PCR) on a circularized 3C library prior to product quantitation. |
Super-classes |
obo:ECO_0000232c |
Sub-classes |
obo:ECO_0007239c obo:ECO_0007135c |
URI | http://purl.obolibrary.org/obo/ECO_0000240 |
---|---|
Super-classes |
obo:ECO_0000059c |
Sub-classes |
obo:ECO_0007810c obo:ECO_0001137c obo:ECO_0000242c obo:ECO_0007728c obo:ECO_0000243c obo:ECO_0001009c |
URI | http://purl.obolibrary.org/obo/ECO_0000241 |
---|---|
Description |
Many environmental factors are subject to modification, such as temperature, pressure, humidity, radiation, and so forth. |
Super-classes |
obo:ECO_0000059c |
Sub-classes |
obo:ECO_0007240c obo:ECO_0007136c |
URI | http://purl.obolibrary.org/obo/ECO_0000242 |
---|---|
Super-classes |
obo:ECO_0000240c |
Sub-classes |
obo:ECO_0007137c obo:ECO_0007241c |
URI | http://purl.obolibrary.org/obo/ECO_0000243 |
---|---|
Super-classes |
obo:ECO_0000240c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b467c) |
Sub-classes |
obo:ECO_0007138c obo:ECO_0007242c |
URI | http://purl.obolibrary.org/obo/ECO_0000244 |
---|---|
Description |
Combinatorial analyses could include experimental or computational results. Examples include: (i) large-scale experiment such as a genome-wide two-hybrid or genome-wide synthetic interactions; (ii) integration of large-scale data sets of various types; and (iii) text-based-computation, e.g. text-mining. For simple sequence comparisons, one should use the sequence similarity analysis evidence type. For microarray results alone, expression pattern analysis is appropriate; whereas, large-scale computational analysis should be used when microarray results are combined with the results of other types of large-scale experiments. |
Super-classes |
obo:ECO_0000352c obo:ECO_0000212c |
Sub-classes |
obo:ECO_0007678c obo:ECO_0007675c obo:ECO_0007745c obo:ECO_0007014c obo:ECO_0007744c obo:ECO_0000245c obo:ECO_0007013c |
URI | http://purl.obolibrary.org/obo/ECO_0000245 |
---|---|
Super-classes |
obo:ECO_0007673c obo:ECO_0000244c |
Sub-classes |
obo:ECO_0007659c obo:ECO_0007666c obo:ECO_0007652c |
URI | http://purl.obolibrary.org/obo/ECO_0000246 |
---|---|
Description |
Merged with ECO:0000053. |
URI | http://purl.obolibrary.org/obo/ECO_0000247 |
---|---|
Super-classes |
obo:ECO_0000200c obo:ECO_0000250c |
Sub-classes |
obo:ECO_0007152c obo:ECO_0000329c obo:ECO_0005560c obo:ECO_0007749c obo:ECO_0005556c obo:ECO_0000330c |
URI | http://purl.obolibrary.org/obo/ECO_0000248 |
---|---|
Super-classes |
obo:ECO_0000249c obo:ECO_0000200c |
Sub-classes |
obo:ECO_0007825c obo:ECO_0005557c obo:ECO_0005561c obo:ECO_0007256c |
URI | http://purl.obolibrary.org/obo/ECO_0000249 |
---|---|
Super-classes |
obo:ECO_0000044c obo:ECO_0000251c obo:ECO_0007669c |
Sub-classes |
obo:ECO_0000248c obo:ECO_0000256c obo:ECO_0000265c |
URI | http://purl.obolibrary.org/obo/ECO_0000250 |
---|---|
Super-classes |
obo:ECO_0000252c obo:ECO_0000044c obo:ECO_0007668c |
Sub-classes |
obo:ECO_0000255c obo:ECO_0000247c obo:ECO_0000266c |
URI | http://purl.obolibrary.org/obo/ECO_0000251 |
---|---|
Super-classes |
obo:ECO_0000501c obo:ECO_0000041c |
Sub-classes |
obo:ECO_0007824c obo:ECO_0000254c obo:ECO_0007826c obo:ECO_0000249c obo:ECO_0007327c |
URI | http://purl.obolibrary.org/obo/ECO_0000252 |
---|---|
Super-classes |
obo:ECO_0000041c obo:ECO_0000352c |
Sub-classes |
obo:ECO_0000318c obo:ECO_0007750c obo:ECO_0007094c obo:ECO_0000250c obo:ECO_0007748c obo:ECO_0007153c obo:ECO_0000317c obo:ECO_0007090c obo:ECO_0000253c obo:ECO_0000319c obo:ECO_0007097c obo:ECO_0007099c obo:ECO_0007096c obo:ECO_0000321c obo:ECO_0000320c obo:ECO_0007098c |
URI | http://purl.obolibrary.org/obo/ECO_0000253 |
---|---|
Super-classes |
obo:ECO_0000252c obo:ECO_0000051c |
URI | http://purl.obolibrary.org/obo/ECO_0000254 |
---|---|
Super-classes |
obo:ECO_0000251c obo:ECO_0000051c |
URI | http://purl.obolibrary.org/obo/ECO_0000255 |
---|---|
Super-classes |
obo:ECO_0000202c obo:ECO_0000250c |
Sub-classes |
obo:ECO_0000260c obo:ECO_0005649c obo:ECO_0000257c |
URI | http://purl.obolibrary.org/obo/ECO_0000256 |
---|---|
Super-classes |
obo:ECO_0000202c obo:ECO_0000249c |
Sub-classes |
obo:ECO_0000259c obo:ECO_0005650c obo:ECO_0000258c |
URI | http://purl.obolibrary.org/obo/ECO_0000257 |
---|---|
Super-classes |
obo:ECO_0000028c obo:ECO_0000255c |
Sub-classes |
obo:ECO_0005658c obo:ECO_0000262c obo:ECO_0005662c obo:ECO_0005624c obo:ECO_0000264c obo:ECO_0005622c |
URI | http://purl.obolibrary.org/obo/ECO_0000258 |
---|---|
Super-classes |
obo:ECO_0000256c obo:ECO_0000028c |
Sub-classes |
obo:ECO_0005623c obo:ECO_0000261c obo:ECO_0005659c obo:ECO_0005625c obo:ECO_0000263c obo:ECO_0005663c |
URI | http://purl.obolibrary.org/obo/ECO_0000259 |
---|---|
Super-classes |
obo:ECO_0000256c obo:ECO_0000029c |
URI | http://purl.obolibrary.org/obo/ECO_0000260 |
---|---|
Super-classes |
obo:ECO_0000029c obo:ECO_0000255c |
URI | http://purl.obolibrary.org/obo/ECO_0000261 |
---|---|
Super-classes |
obo:ECO_0000258c obo:ECO_0000081c |
URI | http://purl.obolibrary.org/obo/ECO_0000262 |
---|---|
Super-classes |
obo:ECO_0000257c obo:ECO_0000081c |
URI | http://purl.obolibrary.org/obo/ECO_0000263 |
---|---|
Super-classes |
obo:ECO_0000083c obo:ECO_0000258c |
URI | http://purl.obolibrary.org/obo/ECO_0000264 |
---|---|
Super-classes |
obo:ECO_0000083c obo:ECO_0000257c |
URI | http://purl.obolibrary.org/obo/ECO_0000265 |
---|---|
Super-classes |
obo:ECO_0000201c obo:ECO_0000249c |
URI | http://purl.obolibrary.org/obo/ECO_0000266 |
---|---|
Super-classes |
obo:ECO_0000250c obo:ECO_0000201c |
URI | http://purl.obolibrary.org/obo/ECO_0000267 |
---|---|
Description |
ELISA is sometimes used in the study of transcriptional regulation to identify a produced protein, especially secreted protein. |
Super-classes |
obo:ECO_0005517c |
Sub-classes |
obo:ECO_0005581c obo:ECO_0007488c |
URI | http://purl.obolibrary.org/obo/ECO_0000268 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b561c) obo:OBI_0000312op some obo:OBI_0000916c |
Sub-classes |
obo:ECO_0005580c obo:ECO_0007487c |
URI | http://purl.obolibrary.org/obo/ECO_0000270 |
---|---|
Super-classes |
obo:ECO_0000008c obo:ECO_0000269c |
Sub-classes |
obo:ECO_0006241c obo:ECO_0005616c obo:ECO_0000291c obo:ECO_0007682c obo:ECO_0005636c obo:ECO_0006002c obo:ECO_0005672c obo:ECO_0000284c obo:ECO_0007088c obo:ECO_0005633c obo:ECO_0005641c obo:ECO_0005648c obo:ECO_0001838c obo:ECO_0005615c obo:ECO_0007007c obo:ECO_0005617c |
URI | http://purl.obolibrary.org/obo/ECO_0000271 |
---|---|
Description |
This general 'array experiment' term should not be used - replace with the specific type of array (e.g. ECO:0000273, ECO:0000276, ECO:0000285, etc.) |
URI | http://purl.obolibrary.org/obo/ECO_0000272 |
---|---|
Super-classes |
obo:ECO_0000101c obo:ECO_0000276c |
URI | http://purl.obolibrary.org/obo/ECO_0000273 |
---|---|
Super-classes |
obo:ECO_0000275c obo:ECO_0000097c |
Sub-classes |
obo:ECO_0000277c |
URI | http://purl.obolibrary.org/obo/ECO_0000274 |
---|---|
Super-classes |
obo:ECO_0000069c obo:ECO_0001198c |
URI | http://purl.obolibrary.org/obo/ECO_0000275 |
---|---|
Super-classes |
obo:ECO_0000058c obo:ECO_0000291c |
Sub-classes |
obo:ECO_0000273c obo:ECO_0000285c obo:ECO_0000276c |
URI | http://purl.obolibrary.org/obo/ECO_0000276 |
---|---|
Super-classes |
obo:ECO_0000275c obo:ECO_0000062c |
Sub-classes |
obo:ECO_0000272c |
URI | http://purl.obolibrary.org/obo/ECO_0000277 |
---|---|
Super-classes |
obo:ECO_0000105c obo:ECO_0000273c |
URI | http://purl.obolibrary.org/obo/ECO_0000278 |
---|---|
Super-classes |
obo:ECO_0000093c obo:ECO_0000269c |
URI | http://purl.obolibrary.org/obo/ECO_0000279 |
---|---|
Super-classes |
obo:ECO_0000314c obo:ECO_0000112c obo:ECO_0000284c |
Sub-classes |
obo:ECO_0006170c |
URI | http://purl.obolibrary.org/obo/ECO_0000281 |
---|---|
Super-classes |
obo:ECO_0000284c obo:ECO_0000114c |
URI | http://purl.obolibrary.org/obo/ECO_0000282 |
---|---|
Super-classes |
obo:ECO_0000284c obo:ECO_0000154c |
URI | http://purl.obolibrary.org/obo/ECO_0000283 |
---|---|
Super-classes |
obo:ECO_0000045c obo:ECO_0000284c |
URI | http://purl.obolibrary.org/obo/ECO_0000284 |
---|---|
Super-classes |
obo:ECO_0000010c obo:ECO_0000270c |
Sub-classes |
obo:ECO_0000281c obo:ECO_0000282c obo:ECO_0000283c obo:ECO_0000279c |
URI | http://purl.obolibrary.org/obo/ECO_0000285 |
---|---|
Super-classes |
obo:ECO_0000275c obo:ECO_0000104c |
URI | http://purl.obolibrary.org/obo/ECO_0000287 |
---|---|
Super-classes |
obo:ECO_0000116c obo:ECO_0000291c |
URI | http://purl.obolibrary.org/obo/ECO_0000288 |
---|---|
Super-classes |
obo:ECO_0001240c obo:ECO_0000110c |
URI | http://purl.obolibrary.org/obo/ECO_0000289 |
---|---|
Super-classes |
obo:ECO_0000047c obo:ECO_0000291c |
URI | http://purl.obolibrary.org/obo/ECO_0000290 |
---|---|
Super-classes |
obo:ECO_0000291c obo:ECO_0000118c |
URI | http://purl.obolibrary.org/obo/ECO_0000291 |
---|---|
Super-classes |
obo:ECO_0000270c obo:ECO_0000009c |
Sub-classes |
obo:ECO_0005653c obo:ECO_0000290c obo:ECO_0000275c obo:ECO_0007144c obo:ECO_0007145c obo:ECO_0006068c obo:ECO_0005657c obo:ECO_0000289c obo:ECO_0007155c obo:ECO_0007154c obo:ECO_0000287c |
URI | http://purl.obolibrary.org/obo/ECO_0000292 |
---|---|
Description |
Morpholino oligonucleotides modify gene expression by blocking access of other molecules to specific, approximately 25-base-long regions of the base-pairing surfaces of ribonucleic acid (RNA). To achieve this anti-sense knockdown technique, delivery of the morpholino can be achieved via microinjection, electroporation, or another method. |
Super-classes |
obo:ECO_0000015c |
Sub-classes |
obo:ECO_0007557c obo:ECO_0006051c |
URI | http://purl.obolibrary.org/obo/ECO_0000293 |
---|---|
Description |
SELEX begins with the synthesis of a large oligonucleotide library, either single-stranded DNA or RNA, which consists of random fixed-length sequences flanked by constant 5' and 3' ends that serve as primers. The library is exposed to a target ligand, typically a protein or small organic compound. Unbound sequences are removed, typically with affinity chromatography. Bound sequences are eluted and the nucleic acid is extracted, followed by PCR amplification (RNA is first reverse transcribed). PCR product is converted to single stranded (DNA) or transcribed (RNA). Oligonucleotides are bound to the ligand again and the process is repeated with increasing elution stringency. After several rounds of the process, recovered oligonucleotides are sequenced and analyzed to reveal the binding specificity of the protein. |
Super-classes |
obo:ECO_0000021c |
Sub-classes |
obo:ECO_0006088c obo:ECO_0007510c obo:ECO_0001812c |
URI | http://purl.obolibrary.org/obo/ECO_0000294 |
---|---|
Description |
Bacterial one-hybrid assay is a method for screening a library of candidate proteins (prey plasmid) for the ability to bind to a target, cis-regulatory element or any other short, DNA binding sequence placed 5' to reporter genes (bait plasmid). Transformation of a bacterial host with two different plasmids is required: One is designed to express the "bait". The other plasmid contains a "prey" which, if bound to by the chimeric fusion product, drives expression of downstream reporter genes. |
Super-classes |
obo:ECO_0000025c |
Restrictions |
obo:IAO_0000136op some obo:GO_0043565c obo:OBI_0000312op some obo:OBI_0001682c |
Sub-classes |
obo:ECO_0007576c obo:ECO_0006089c |
URI | http://purl.obolibrary.org/obo/ECO_0000295 |
---|---|
Description |
Total RNA is isolated from cells and mRNA is purified by targeting the 3' polyadenylated (poly(A)) tail with poly(T) oligos covalently attached to a substrate. Next, cDNA fragments are generated either by hydrolysis of RNA into 200-300 base oligonucleotides, preceded by reverse transcription, or by reverse transcription initiated by random primers. The cDNA second strand is synthesized, fragments are adapter ligated and high-throughput sequencing is performed by Roche 454, Illumina, ABI-SOLiD, or another HT sequencing technology. Resulting sort reads are aligned against a reference genome, and downstream analysis is performed. |
Super-classes |
obo:ECO_0000009c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001271c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b654c) |
Sub-classes |
obo:ECO_0006239c obo:ECO_0006069c obo:ECO_0006068c obo:ECO_0001560c obo:ECO_0000342c |
URI | http://purl.obolibrary.org/obo/ECO_0000298 |
---|---|
Description |
In the embryos of some organisms, inhibition of cytokinesis blocks neither the cell cycle nor the unfolding of the developmental program. As such, embryonic morphology can be frozen, allowing analysis of the developmental fate of each cell present at the time of cleavage arrest. |
Super-classes |
obo:ECO_0000059c |
Sub-classes |
obo:ECO_0007730c obo:ECO_0000299c obo:ECO_0007811c |
URI | http://purl.obolibrary.org/obo/ECO_0000299 |
---|---|
Description |
Cytochalasin inhibits cytokinesis by blocking the formation of contractile microfilaments. |
Super-classes |
obo:ECO_0000298c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b667c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b662c) obo:IAO_0000136op some obo:GO_0072749c obo:OBI_0000312op some obo:OBI_0001689c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b667c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b662c) |
Sub-classes |
obo:ECO_0007141c obo:ECO_0007245c |
URI | http://purl.obolibrary.org/obo/ECO_0000300 |
---|---|
Description |
This term describes immunolocalization of the protein; to describe transcriptional activation, use the term "localization of green fluorescent protein transcript". |
Super-classes |
obo:ECO_0000087c |
Sub-classes |
obo:ECO_0007142c obo:ECO_0007246c |
URI | http://purl.obolibrary.org/obo/ECO_0000301 |
---|---|
Description |
This term describes immunolocalization of the protein; to describe transcriptional activation, use the term "localization of LacZ transcript". |
Super-classes |
obo:ECO_0000087c |
Sub-classes |
obo:ECO_0007247c obo:ECO_0007143c |
URI | http://purl.obolibrary.org/obo/ECO_0000302 |
---|---|
Super-classes |
obo:ECO_0006155c obo:ECO_0000204c |
Sub-classes |
obo:ECO_0000304c obo:ECO_0000303c obo:ECO_0006216c |
URI | http://purl.obolibrary.org/obo/ECO_0000303 |
---|---|
Super-classes |
obo:ECO_0000302c obo:ECO_0000034c |
URI | http://purl.obolibrary.org/obo/ECO_0000304 |
---|---|
Super-classes |
obo:ECO_0000302c obo:ECO_0000033c |
Sub-classes |
obo:ECO_0006017c |
URI | http://purl.obolibrary.org/obo/ECO_0000305 |
---|---|
Super-classes |
obo:ECO_0007751c obo:ECO_0000205c |
Sub-classes |
obo:ECO_0006019c obo:ECO_0000307c obo:ECO_0007752c obo:ECO_0000306c |
URI | http://purl.obolibrary.org/obo/ECO_0000306 |
---|---|
Super-classes |
obo:ECO_0000001c obo:ECO_0000305c |
URI | http://purl.obolibrary.org/obo/ECO_0000307 |
---|---|
Super-classes |
obo:ECO_0000305c obo:ECO_0000035c |
URI | http://purl.obolibrary.org/obo/ECO_0000308 |
---|---|
Description |
First, a characteristic of the most recent common ancestor (MRCA) is inferred from experimental evidence in descendants; this is followed by inferring a characteristic of a descendant of the MRCA. This type of evidence can be used in support of both positive and "not" GO annotations. |
Super-classes |
obo:ECO_0000080c |
Sub-classes |
obo:ECO_0007328c obo:ECO_0000318c |
URI | http://purl.obolibrary.org/obo/ECO_0000309 |
---|---|
Description |
Complementary DNA (cDNA) is synthesized from microgram quantities of mRNA using first-strand cDNA primer (oligo dT12-18) and reverse transcriptase in the presence of trehalose and sorbitol, followed by selection of full-length cDNA with biotinylated cap-trapper. Linkers are attached to the 5' ends of full-length enriched cDNAs to introduce a recognition site for the restriction endonuclease MmeI, which creates a two base overhang. After amplification, sequencing tags are concatenated for high-throughput sequencing. Resulting sort reads are aligned against a reference genome, and downstream analysis is performed. |
Super-classes |
obo:ECO_0000009c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001674c |
Sub-classes |
obo:ECO_0007248c obo:ECO_0007144c |
URI | http://purl.obolibrary.org/obo/ECO_0000310 |
---|---|
Description |
NanoCAGE captures the 5' ends of molecules by template switching. When polymerizing the cDNA of a capped mRNA, the reverse transcriptase adds extra cytosines that are complementary to the cap. Each 5' full length cDNAs is extended upon hybridization of the riboguanosine-tailed template switching oligonucleotides to these extra cytosines. In semisuppressive PCR, the short templates fold intramolecularly and prevent the binding of primers, which precludes amplification; longer molecules are less likely to fold and are thus amplified. Templates derived from reaction artifacts form stable homoduplexes, also precluding amplification. After template switching, semisuppressive PCR, and EcoP151 cleavage, 25-bp tags are ligated to bar code-containing oligonucleotide adaptors. After PCR amplification, the nanoCAGE tags are sequenced by synthesis. NanoCAGE requires as little as 10 nanograms of total RNA. |
Super-classes |
obo:ECO_0000009c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001673c |
Sub-classes |
obo:ECO_0007145c obo:ECO_0007249c |
URI | http://purl.obolibrary.org/obo/ECO_0000311 |
---|---|
Super-classes |
obo:ECO_0006151c |
Sub-classes |
obo:ECO_0000313c obo:ECO_0000312c |
URI | http://purl.obolibrary.org/obo/ECO_0000312 |
---|---|
Super-classes |
obo:ECO_0006155c obo:ECO_0000311c |
URI | http://purl.obolibrary.org/obo/ECO_0000313 |
---|---|
Super-classes |
obo:ECO_0006156c obo:ECO_0000311c |
Sub-classes |
obo:ECO_0000322c obo:ECO_0000323c |
URI | http://purl.obolibrary.org/obo/ECO_0000315 |
---|---|
Super-classes |
obo:ECO_0007634c obo:ECO_0000015c |
Sub-classes |
obo:ECO_0007165c obo:ECO_0006095c obo:ECO_0006050c obo:ECO_0005530c obo:ECO_0007117c obo:ECO_0006101c obo:ECO_0006051c obo:ECO_0007089c obo:ECO_0001247c obo:ECO_0007166c obo:ECO_0007168c obo:ECO_0001161c obo:ECO_0001175c obo:ECO_0001179c obo:ECO_0007163c obo:ECO_0007001c obo:ECO_0006049c obo:ECO_0007118c obo:ECO_0006099c obo:ECO_0007167c obo:ECO_0006052c obo:ECO_0007092c obo:ECO_0005667c |
URI | http://purl.obolibrary.org/obo/ECO_0000316 |
---|---|
Super-classes |
obo:ECO_0007634c obo:ECO_0000011c |
Sub-classes |
obo:ECO_0006096c obo:ECO_0006094c obo:ECO_0007003c obo:ECO_0006091c |
URI | http://purl.obolibrary.org/obo/ECO_0000317 |
---|---|
Super-classes |
obo:ECO_0000177c obo:ECO_0000252c |
Sub-classes |
obo:ECO_0000354c |
URI | http://purl.obolibrary.org/obo/ECO_0000318 |
---|---|
Super-classes |
obo:ECO_0000252c obo:ECO_0000308c |
URI | http://purl.obolibrary.org/obo/ECO_0000319 |
---|---|
Super-classes |
obo:ECO_0000214c obo:ECO_0000252c |
URI | http://purl.obolibrary.org/obo/ECO_0000320 |
---|---|
Super-classes |
obo:ECO_0000216c obo:ECO_0000252c |
URI | http://purl.obolibrary.org/obo/ECO_0000321 |
---|---|
Super-classes |
obo:ECO_0000215c obo:ECO_0000252c |
URI | http://purl.obolibrary.org/obo/ECO_0000322 |
---|---|
Super-classes |
obo:ECO_0000313c |
URI | http://purl.obolibrary.org/obo/ECO_0000323 |
---|---|
Super-classes |
obo:ECO_0000313c |
URI | http://purl.obolibrary.org/obo/ECO_0000324 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000185c |
Sub-classes |
obo:ECO_0007363c obo:ECO_0001026c obo:ECO_0001097c obo:ECO_0001256c obo:ECO_0001051c obo:ECO_0001098c |
URI | http://purl.obolibrary.org/obo/ECO_0000325 |
---|---|
Super-classes |
obo:ECO_0000006c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b741c) obo:OBI_0000312op some obo:OBI_0001630c |
Sub-classes |
obo:ECO_0000140c obo:ECO_0007681c obo:ECO_0001010c obo:ECO_0001049c obo:ECO_0001809c obo:ECO_0001052c obo:ECO_0007680c |
URI | http://purl.obolibrary.org/obo/ECO_0000326 |
---|---|
Super-classes |
obo:ECO_0000200c |
Sub-classes |
obo:ECO_0000327c obo:ECO_0007749c obo:ECO_0007825c obo:ECO_0000328c |
URI | http://purl.obolibrary.org/obo/ECO_0000327 |
---|---|
Description |
This term is used by the NCBI Reference Sequences (RefSeq) in support of sequences that have the same splice pattern as a RefSeq transcript. If such full transcript information is not available, RefSeq reports sequences that match the splice pattern of a coding sequence (CDS) annotated on a RefSeq, supported by the evidence term ECO:0000328 or a child. |
Super-classes |
obo:ECO_0000326c |
Sub-classes |
obo:ECO_0000332c obo:ECO_0000329c |
URI | http://purl.obolibrary.org/obo/ECO_0000328 |
---|---|
Description |
This term is used by the NCBI Reference Sequences (RefSeq) in support of sequences that match the splice pattern of a coding sequence (CDS) annotated on a RefSeq, but for which full transcript information is unavailable. For sequences that have the same splice pattern as a whole RefSeq transcript, use the evidence term ECO:0000327 or a child. |
Super-classes |
obo:ECO_0000326c |
Sub-classes |
obo:ECO_0000330c obo:ECO_0000331c |
URI | http://purl.obolibrary.org/obo/ECO_0000329 |
---|---|
Description |
This term is used by the NCBI Reference Sequences (RefSeq) in support of sequences that have the same splice pattern as a RefSeq transcript. If such full transcript information is not available, RefSeq reports sequences that match the splice pattern of a coding sequence (CDS) annotated on a RefSeq, supported by the evidence term ECO:0000328 or a child. |
Super-classes |
obo:ECO_0000247c obo:ECO_0000327c |
URI | http://purl.obolibrary.org/obo/ECO_0000330 |
---|---|
Description |
This term is used by the NCBI Reference Sequences (RefSeq) in support of sequences that match the splice pattern of a coding sequence (CDS) annotated on a RefSeq, but for which full transcript information is unavailable. For sequences that have the same splice pattern as a whole RefSeq transcript, use the evidence term ECO:0000327 or a child. |
Super-classes |
obo:ECO_0000328c obo:ECO_0000247c |
URI | http://purl.obolibrary.org/obo/ECO_0000331 |
---|---|
Description |
This term is used by the NCBI Reference Sequences (RefSeq) in support of sequences that match the splice pattern of a coding sequence (CDS) annotated on a RefSeq, but for which full transcript information is unavailable. For sequences that have the same splice pattern as a whole RefSeq transcript, use the evidence term ECO:0000327 or a child. |
Super-classes |
obo:ECO_0007825c obo:ECO_0000328c |
URI | http://purl.obolibrary.org/obo/ECO_0000332 |
---|---|
Description |
This term is used by the NCBI Reference Sequences (RefSeq) in support of sequences that have the same splice pattern as a RefSeq transcript. If such full transcript information is not available, RefSeq reports sequences that match the splice pattern of a coding sequence (CDS) annotated on a RefSeq, supported by the evidence term ECO:0000328 or a child. |
Super-classes |
obo:ECO_0007825c obo:ECO_0000327c |
URI | http://purl.obolibrary.org/obo/ECO_0000333 |
---|---|
Description |
Electrophoretic mobility is a function of both the length and charge of a protein. The protein sample is linearized with sodium dodecyl sulfate (SDS), an anionic detergent. Typically, polypeptides bound with SDS possess an even distribution of charge per unit mass, and subsequent fractionation is by size. |
Super-classes |
obo:ECO_0000337c |
Sub-classes |
obo:ECO_0007770c obo:ECO_0007689c obo:ECO_0000112c |
URI | http://purl.obolibrary.org/obo/ECO_0000334 |
---|---|
Description |
An example of an instrument used to analyze particle sizes and counts is the Beckman Coulter® Z Series system. |
Super-classes |
obo:ECO_0000002c |
Sub-classes |
obo:ECO_0007146c obo:ECO_0007250c |
URI | http://purl.obolibrary.org/obo/ECO_0000335 |
---|---|
Description |
Two examples of substance quantification assay are (i) measuring how much of a radiolabelled compound is taken up by a cell and (ii) measuring how much of a substrate is turned over by a given enzyme. |
Super-classes |
obo:ECO_0000002c |
Sub-classes |
obo:ECO_0007685c obo:ECO_0007805c obo:ECO_0007015c |
URI | http://purl.obolibrary.org/obo/ECO_0000336 |
---|---|
Super-classes |
obo:ECO_0005007c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000978c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b768c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b763c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b768c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b763c) |
Sub-classes |
obo:ECO_0007251c obo:ECO_0007147c |
URI | http://purl.obolibrary.org/obo/ECO_0000337 |
---|---|
Description |
Molecules typically separated include DNA, RNA, or protein. The gel is typically made of agarose, polyacrylamide, or starch. |
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b780c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b775c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b780c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b775c) obo:IAO_0000136op some obo:OBI_0600051c |
Sub-classes |
obo:ECO_0001025c obo:ECO_0000338c obo:ECO_0001029c obo:ECO_0005503c obo:ECO_0007688c obo:ECO_0007769c obo:ECO_0000333c obo:ECO_0000339c obo:ECO_0006262c |
URI | http://purl.obolibrary.org/obo/ECO_0000338 |
---|---|
Super-classes |
obo:ECO_0000337c |
Sub-classes |
obo:ECO_0007148c obo:ECO_0007252c |
URI | http://purl.obolibrary.org/obo/ECO_0000339 |
---|---|
Description |
The first dimension gel is intentionally run at low voltage in low percentage agarose to separate DNA molecules in proportion to their mass. The second dimension is run at high voltage in a gel of higher agarose concentration in the presence of ethidium bromide so that the mobility of a non-linear molecule is drastically influenced by its shape. |
Super-classes |
obo:ECO_0000337c |
Sub-classes |
obo:ECO_0007149c obo:ECO_0007253c |
URI | http://purl.obolibrary.org/obo/ECO_0000340 |
---|---|
Description |
Loss per generation is determined by comparing colony numbers on selective and non-selective media. |
Super-classes |
obo:ECO_0000006c |
Restrictions |
obo:IAO_0000136op some obo:GO_0006276c obo:OBI_0000312op some obo:OBI_0000964c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b787c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b792c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b787c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b792c) |
Sub-classes |
obo:ECO_0007254c obo:ECO_0007150c |
URI | http://purl.obolibrary.org/obo/ECO_0000341 |
---|---|
Super-classes |
obo:ECO_0000020c |
Sub-classes |
obo:ECO_0007151c obo:ECO_0007255c |
URI | http://purl.obolibrary.org/obo/ECO_0000342 |
---|---|
Description |
RNA-seq alignment intron location evidence is used by NCBI RefSeq (http://www.ncbi.nlm.nih.gov/refseq). Exon-exon boundaries (or intron locations) of a RefSeq transcript, as determined by aligning the transcript to a reference chromosome, are compared to intron locations supported by RNAseq data. |
Super-classes |
obo:ECO_0000295c |
Sub-classes |
obo:ECO_0000347c obo:ECO_0006172c obo:ECO_0000346c obo:ECO_0000344c obo:ECO_0000343c |
URI | http://purl.obolibrary.org/obo/ECO_0000343 |
---|---|
Description |
Full support entails that all exon pairs represented in the transcript are supported. For example, for a transcript containing five exons, if liver RNA-seq reads support all four introns but brain RNA-seq supports only three introns, then the liver data fully support the transcript exons whereas the brain data do not. |
Super-classes |
obo:ECO_0000342c |
Sub-classes |
obo:ECO_0000349c obo:ECO_0000348c |
URI | http://purl.obolibrary.org/obo/ECO_0000344 |
---|---|
Description |
Partial support can occur in two ways. First, one or more exon-exon pair (intron) is not supported by any RNA-seq sample included in the analysis. Second, no single RNA-seq sample provides support for all exon-exon pairs (introns) represented in a transcript, but all represented exons are supported by at least one sample. |
Super-classes |
obo:ECO_0000342c |
Sub-classes |
obo:ECO_0000350c obo:ECO_0000351c |
URI | http://purl.obolibrary.org/obo/ECO_0000345 |
---|---|
Super-classes |
obo:ECO_0000200c |
Sub-classes |
obo:ECO_0007256c obo:ECO_0007152c |
URI | http://purl.obolibrary.org/obo/ECO_0000346 |
---|---|
Super-classes |
obo:ECO_0000342c obo:ECO_0006068c |
Sub-classes |
obo:ECO_0000351c obo:ECO_0000349c obo:ECO_0006174c |
URI | http://purl.obolibrary.org/obo/ECO_0000347 |
---|---|
Super-classes |
obo:ECO_0000342c obo:ECO_0006069c |
Sub-classes |
obo:ECO_0000348c obo:ECO_0006173c obo:ECO_0000350c |
URI | http://purl.obolibrary.org/obo/ECO_0000348 |
---|---|
Super-classes |
obo:ECO_0000347c obo:ECO_0000343c |
URI | http://purl.obolibrary.org/obo/ECO_0000349 |
---|---|
Super-classes |
obo:ECO_0000343c obo:ECO_0000346c |
URI | http://purl.obolibrary.org/obo/ECO_0000350 |
---|---|
Super-classes |
obo:ECO_0000347c obo:ECO_0000344c |
URI | http://purl.obolibrary.org/obo/ECO_0000351 |
---|---|
Super-classes |
obo:ECO_0000346c obo:ECO_0000344c |
URI | http://purl.obolibrary.org/obo/ECO_0000352 |
---|---|
Super-classes |
obo:ECO_0000000c |
Restrictions |
obo:ECO_9000000op some obo:ECO_0000218c |
Sub-classes |
obo:ECO_0007751c obo:ECO_0005610c obo:ECO_0007668c obo:ECO_0006056c obo:ECO_0007746c obo:ECO_0006155c obo:ECO_0000244c obo:ECO_0005542c obo:ECO_0005547c obo:ECO_0000252c obo:ECO_0005543c obo:ECO_0000269c obo:ECO_0007747c |
URI | http://purl.obolibrary.org/obo/ECO_0000353 |
---|---|
Super-classes |
obo:ECO_0000021c obo:ECO_0000314c |
Sub-classes |
obo:ECO_0001181c obo:ECO_0006303c obo:ECO_0006088c obo:ECO_0006329c obo:ECO_0001227c obo:ECO_0001164c obo:ECO_0001269c obo:ECO_0001807c obo:ECO_0006277c obo:ECO_0006293c obo:ECO_0001226c obo:ECO_0006327c obo:ECO_0006081c obo:ECO_0006074c obo:ECO_0006075c |
URI | http://purl.obolibrary.org/obo/ECO_0000354 |
---|---|
Super-classes |
obo:ECO_0000317c obo:ECO_0000084c |
URI | http://purl.obolibrary.org/obo/ECO_0000355 |
---|---|
Description |
Example of use: "The presence of paired evaginated hemispheres and olfactory bulbs in both agnathan and gnathostome radiations suggests that such hemispheres were also present in the common ancestor." PMID: 7013637. Northcutt RG. (1981) Evolution of the telencephalon in nonmammals. Ann. Rev. Neurosci. |
Super-classes |
obo:ECO_0000080c |
Sub-classes |
obo:ECO_0007153c obo:ECO_0007257c |
URI | http://purl.obolibrary.org/obo/ECO_0000358 |
---|---|
Super-classes |
obo:ECO_0000009c |
Sub-classes |
obo:ECO_0007258c obo:ECO_0007154c |
URI | http://purl.obolibrary.org/obo/ECO_0000359 |
---|---|
Super-classes |
obo:ECO_0000009c |
Sub-classes |
obo:ECO_0007155c obo:ECO_0007259c |
URI | http://purl.obolibrary.org/obo/ECO_0000360 |
---|---|
Super-classes |
obo:ECO_0000006c |
Sub-classes |
obo:ECO_0007156c obo:ECO_0007260c |
URI | http://purl.obolibrary.org/obo/ECO_0000361 |
---|---|
Description |
Inference is the process of deriving logical conclusions from premises known or assumed to be true, or alternatively, arriving at conclusions via some non-logical means of observation of patterns of facts, which can result in identifying new meanings and contexts for understanding. Given the evidence provided by a set of premises, deductive reasoning involves drawing conclusions that necessarily follow, i.e. are certain, whereas inductive reasoning generates conclusions that are likely to be, but are not necessarily, true. |
Super-classes |
obo:ECO_0000000c |
Sub-classes |
obo:ECO_0006185c obo:ECO_0000362c obo:ECO_0000205c obo:ECO_0007850c obo:ECO_0007751c obo:ECO_0007832c |
URI | http://purl.obolibrary.org/obo/ECO_0000362 |
---|---|
Super-classes |
obo:ECO_0000361c obo:ECO_0007672c |
Sub-classes |
obo:ECO_0000363c obo:ECO_0007631c |
URI | http://purl.obolibrary.org/obo/ECO_0000363 |
---|---|
Super-classes |
obo:ECO_0007669c obo:ECO_0000362c obo:ECO_0007832c |
Sub-classes |
obo:ECO_0000364c obo:ECO_0000366c |
URI | http://purl.obolibrary.org/obo/ECO_0000364 |
---|---|
Super-classes |
obo:ECO_0000363c |
URI | http://purl.obolibrary.org/obo/ECO_0000366 |
---|---|
Super-classes |
obo:ECO_0000363c |
URI | http://purl.obolibrary.org/obo/ECO_0000501 |
---|---|
Super-classes |
obo:ECO_0000000c |
Restrictions |
obo:ECO_9000000op some obo:ECO_0000203c |
Sub-classes |
obo:ECO_0000251c obo:ECO_0007669c obo:ECO_0007832c obo:ECO_0006156c obo:ECO_0007297c obo:ECO_0007827c obo:ECO_0000213c obo:ECO_0006057c |
URI | http://purl.obolibrary.org/obo/ECO_0001001 |
---|---|
Super-classes |
obo:ECO_0005007c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b844c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b849c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b844c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b849c) |
Sub-classes |
obo:ECO_0007335c obo:ECO_0001138c |
URI | http://purl.obolibrary.org/obo/ECO_0001002 |
---|---|
Super-classes |
obo:ECO_0001565c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b857c) obo:OBI_0000312op some obo:OBI_0000366c obo:IAO_0000136op some obo:GO_0050482c |
Sub-classes |
obo:ECO_0001142c obo:ECO_0007339c |
URI | http://purl.obolibrary.org/obo/ECO_0001003 |
---|---|
Super-classes |
obo:ECO_0005008c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000669c |
Sub-classes |
obo:ECO_0001141c obo:ECO_0007338c |
URI | http://purl.obolibrary.org/obo/ECO_0001004 |
---|---|
Super-classes |
obo:ECO_0005012c |
Restrictions |
obo:IAO_0000136op some obo:GO_0001906c obo:OBI_0000312op some obo:OBI_9999994c |
Sub-classes |
obo:ECO_0001139c obo:ECO_0007336c |
URI | http://purl.obolibrary.org/obo/ECO_0001005 |
---|---|
Super-classes |
obo:ECO_0005019c |
Sub-classes |
obo:ECO_0001140c obo:ECO_0007337c |
URI | http://purl.obolibrary.org/obo/ECO_0001006 |
---|---|
Super-classes |
obo:ECO_0001565c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b868c) obo:OBI_0000312op some obo:OBI_0000964c obo:IAO_0000136op some obo:GO_0060352c |
Sub-classes |
obo:ECO_0007340c obo:ECO_0001143c |
URI | http://purl.obolibrary.org/obo/ECO_0001007 |
---|---|
Super-classes |
obo:ECO_0005502c |
Restrictions |
obo:IAO_0000136op some (obo:GO_0008150c and n91afa4cc91624519895f2f4dded8ec52b874c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b880c) obo:OBI_0000312op some (obo:GO_0008150c and n91afa4cc91624519895f2f4dded8ec52b874c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b880c) obo:OBI_0000312op some obo:OBI_0000978c |
Sub-classes |
obo:ECO_0001144c obo:ECO_0007341c |
URI | http://purl.obolibrary.org/obo/ECO_0001008 |
---|---|
Super-classes |
obo:ECO_0005004c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000443c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b886c) |
Sub-classes |
obo:ECO_0007342c obo:ECO_0001145c |
URI | http://purl.obolibrary.org/obo/ECO_0001009 |
---|---|
Super-classes |
obo:ECO_0000240c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b891c) |
Sub-classes |
obo:ECO_0007343c obo:ECO_0001146c |
URI | http://purl.obolibrary.org/obo/ECO_0001010 |
---|---|
Super-classes |
obo:ECO_0000325c |
Sub-classes |
obo:ECO_0007344c obo:ECO_0001147c |
URI | http://purl.obolibrary.org/obo/ECO_0001011 |
---|---|
Super-classes |
obo:ECO_0005034c |
Sub-classes |
obo:ECO_0001148c obo:ECO_0007345c |
URI | http://purl.obolibrary.org/obo/ECO_0001012 |
---|---|
Super-classes |
obo:ECO_0000059c |
Sub-classes |
obo:ECO_0007346c obo:ECO_0001149c |
URI | http://purl.obolibrary.org/obo/ECO_0001013 |
---|---|
Super-classes |
obo:ECO_0000040c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001593c obo:IAO_0000136op some obo:OBI_0001702c |
Sub-classes |
obo:ECO_0007347c obo:ECO_0001150c |
URI | http://purl.obolibrary.org/obo/ECO_0001014 |
---|---|
Super-classes |
obo:ECO_0000040c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001593c obo:IAO_0000136op some obo:GO_0042605c |
Sub-classes |
obo:ECO_0001151c obo:ECO_0007349c |
URI | http://purl.obolibrary.org/obo/ECO_0001015 |
---|---|
Super-classes |
obo:ECO_0000040c |
Sub-classes |
obo:ECO_0007350c obo:ECO_0001152c |
URI | http://purl.obolibrary.org/obo/ECO_0001016 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000443c and obo:OBI_0000630c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b900c) obo:OBI_0000312op some (obo:OBI_0000443c and obo:OBI_0000630c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b900c) |
Sub-classes |
obo:ECO_0007351c obo:ECO_0001153c |
URI | http://purl.obolibrary.org/obo/ECO_0001017 |
---|---|
Super-classes |
obo:ECO_0005021c |
Restrictions |
obo:IAO_0000136op some obo:GO_0060326c |
Sub-classes |
obo:ECO_0007352c obo:ECO_0001154c |
URI | http://purl.obolibrary.org/obo/ECO_0001018 |
---|---|
Super-classes |
obo:ECO_0001107c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b915c) obo:OBI_0000312op some obo:OBI_0000664c |
Sub-classes |
obo:ECO_0001155c obo:ECO_0007353c |
URI | http://purl.obolibrary.org/obo/ECO_0001019 |
---|---|
Super-classes |
obo:ECO_0005034c |
Sub-classes |
obo:ECO_0001156c obo:ECO_0007355c |
URI | http://purl.obolibrary.org/obo/ECO_0001020 |
---|---|
Super-classes |
obo:ECO_0001565c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b926c) obo:OBI_0000312op some obo:OBI_0000978c obo:IAO_0000136op some obo:GO_0008283c |
Sub-classes |
obo:ECO_0007356c obo:ECO_0001157c |
URI | http://purl.obolibrary.org/obo/ECO_0001021 |
---|---|
Super-classes |
obo:ECO_0001565c |
Restrictions |
obo:IAO_0000136op some obo:GO_0009987c obo:OBI_0000312op some obo:OBI_0001977c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b934c) |
Sub-classes |
obo:ECO_0001158c obo:ECO_0007357c |
URI | http://purl.obolibrary.org/obo/ECO_0001022 |
---|---|
Super-classes |
obo:ECO_0005019c |
Sub-classes |
obo:ECO_0001159c obo:ECO_0007358c |
URI | http://purl.obolibrary.org/obo/ECO_0001023 |
---|---|
Super-classes |
obo:ECO_0005517c |
Sub-classes |
obo:ECO_0007359c obo:ECO_0001160c |
URI | http://purl.obolibrary.org/obo/ECO_0001024 |
---|---|
Super-classes |
obo:ECO_0000015c |
Sub-classes |
obo:ECO_0001161c obo:ECO_0007360c |
URI | http://purl.obolibrary.org/obo/ECO_0001025 |
---|---|
Super-classes |
obo:ECO_0000337c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b941c and obo:OBI_0001146c and n91afa4cc91624519895f2f4dded8ec52b949c) obo:IAO_0000136op some obo:GO_0005488c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b941c and obo:OBI_0001146c and n91afa4cc91624519895f2f4dded8ec52b949c) |
Sub-classes |
obo:ECO_0001162c obo:ECO_0007361c |
URI | http://purl.obolibrary.org/obo/ECO_0001026 |
---|---|
Super-classes |
obo:ECO_0000324c |
Restrictions |
obo:IAO_0000136op some obo:GO_0033036c |
Sub-classes |
obo:ECO_0007362c obo:ECO_0001163c |
URI | http://purl.obolibrary.org/obo/ECO_0001027 |
---|---|
Super-classes |
obo:ECO_0000002c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000978c and n91afa4cc91624519895f2f4dded8ec52b961c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b955c) obo:OBI_0000312op some (obo:OBI_0000978c and n91afa4cc91624519895f2f4dded8ec52b961c and obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b955c) |
Sub-classes |
obo:ECO_0007365c obo:ECO_0001165c |
URI | http://purl.obolibrary.org/obo/ECO_0001028 |
---|---|
Super-classes |
obo:ECO_0000021c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000288c |
Sub-classes |
obo:ECO_0001164c obo:ECO_0007364c |
URI | http://purl.obolibrary.org/obo/ECO_0001029 |
---|---|
Super-classes |
obo:ECO_0000337c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0302736c obo:IAO_0000136op some obo:GO_0006974c |
Sub-classes |
obo:ECO_0007366c obo:ECO_0001166c |
URI | http://purl.obolibrary.org/obo/ECO_0001030 |
---|---|
Super-classes |
obo:ECO_0001091c |
Sub-classes |
obo:ECO_0001168c obo:ECO_0007369c |
URI | http://purl.obolibrary.org/obo/ECO_0001031 |
---|---|
Super-classes |
obo:ECO_0001090c |
Sub-classes |
obo:ECO_0001167c obo:ECO_0007367c |
URI | http://purl.obolibrary.org/obo/ECO_0001032 |
---|---|
Super-classes |
obo:ECO_0000059c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b973c and obo:GO_0009058c and obo:GO_0010467c) obo:IAO_0000136op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b973c and obo:GO_0009058c and obo:GO_0010467c) |
Sub-classes |
obo:ECO_0007371c obo:ECO_0001169c |
URI | http://purl.obolibrary.org/obo/ECO_0001033 |
---|---|
Super-classes |
obo:ECO_0000024c |
Restrictions |
obo:IAO_0000136op some obo:GO_0005515c obo:OBI_0000312op some obo:OBI_0001591c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b981c) |
Sub-classes |
obo:ECO_0007372c obo:ECO_0001170c |
URI | http://purl.obolibrary.org/obo/ECO_0001034 |
---|---|
Super-classes |
obo:ECO_0005031c |
Sub-classes |
obo:ECO_0001823c obo:ECO_0001171c obo:ECO_0007374c |
URI | http://purl.obolibrary.org/obo/ECO_0001035 |
---|---|
Super-classes |
obo:ECO_0001050c |
Sub-classes |
obo:ECO_0007375c obo:ECO_0001130c obo:ECO_0001172c |
URI | http://purl.obolibrary.org/obo/ECO_0001036 |
---|---|
Super-classes |
obo:ECO_0005034c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000443c and obo:OBI_0001977c) |
Sub-classes |
obo:ECO_0001173c obo:ECO_0007377c |
URI | http://purl.obolibrary.org/obo/ECO_0001037 |
---|---|
Super-classes |
obo:ECO_0005019c |
Sub-classes |
obo:ECO_0001174c obo:ECO_0007378c |
URI | http://purl.obolibrary.org/obo/ECO_0001038 |
---|---|
Description |
As a child of 'experimental phenotypic evidence', this is not to be confused with the biological processes deletion mutation / deletion deficiency in which DNA is lost during DNA replication. |
Super-classes |
obo:ECO_0000015c |
Sub-classes |
obo:ECO_0007379c obo:ECO_0001175c |
URI | http://purl.obolibrary.org/obo/ECO_0001039 |
---|---|
Super-classes |
obo:ECO_0005034c |
Restrictions |
obo:IAO_0000136op some obo:GO_0006309c |
Sub-classes |
obo:ECO_0001176c obo:ECO_0007380c |
URI | http://purl.obolibrary.org/obo/ECO_0001040 |
---|---|
Super-classes |
obo:ECO_0005518c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b991c and obo:OBI_0002171c and n91afa4cc91624519895f2f4dded8ec52b996c) obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b991c and obo:OBI_0002171c and n91afa4cc91624519895f2f4dded8ec52b996c) |
Sub-classes |
obo:ECO_0007381c obo:ECO_0001177c |
URI | http://purl.obolibrary.org/obo/ECO_0001042 |
---|---|
Super-classes |
obo:ECO_0000015c |
Sub-classes |
obo:ECO_0007382c obo:ECO_0001179c |
URI | http://purl.obolibrary.org/obo/ECO_0001043 |
---|---|
Super-classes |
obo:ECO_0000269c obo:ECO_0001044c |
URI | http://purl.obolibrary.org/obo/ECO_0001044 |
---|---|
Super-classes |
obo:ECO_0005517c |
Sub-classes |
obo:ECO_0001043c obo:ECO_0007334c |
URI | http://purl.obolibrary.org/obo/ECO_0001045 |
---|---|
Super-classes |
obo:ECO_0000023c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000443c and n91afa4cc91624519895f2f4dded8ec52b1006c) obo:IAO_0000136op some obo:GO_0010467c |
Sub-classes |
obo:ECO_0001180c obo:ECO_0007383c |
URI | http://purl.obolibrary.org/obo/ECO_0001046 |
---|---|
Super-classes |
obo:ECO_0000021c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0001591c and n91afa4cc91624519895f2f4dded8ec52b1019c) |
Sub-classes |
obo:ECO_0007385c obo:ECO_0001181c |
URI | http://purl.obolibrary.org/obo/ECO_0001047 |
---|---|
Super-classes |
obo:ECO_0001534c obo:ECO_0001836c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0001683c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b1026c) obo:IAO_0000136op some obo:GO_0051276c |
Sub-classes |
obo:ECO_0001182c obo:ECO_0007386c |
URI | http://purl.obolibrary.org/obo/ECO_0001048 |
---|---|
Super-classes |
obo:ECO_0006273c |
Sub-classes |
obo:ECO_0007387c obo:ECO_0001183c |
URI | http://purl.obolibrary.org/obo/ECO_0001049 |
---|---|
Super-classes |
obo:ECO_0000325c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0001630c and n91afa4cc91624519895f2f4dded8ec52b1036c) |
Sub-classes |
obo:ECO_0001184c obo:ECO_0007388c |
URI | http://purl.obolibrary.org/obo/ECO_0001050 |
---|---|
Super-classes |
obo:ECO_0001051c |
Restrictions |
obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b1041c) |
Sub-classes |
obo:ECO_0001035c obo:ECO_0001185c obo:ECO_0007376c |
URI | http://purl.obolibrary.org/obo/ECO_0001051 |
---|---|
Super-classes |
obo:ECO_0000324c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0600020c obo:IAO_0000136op some obo:GO_0048532c |
Sub-classes |
obo:ECO_0007389c obo:ECO_0001187c obo:ECO_0001050c |
URI | http://purl.obolibrary.org/obo/ECO_0001052 |
---|---|
Super-classes |
obo:ECO_0000325c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0002116c |
Sub-classes |
obo:ECO_0001272c obo:ECO_0007472c |
URI | http://purl.obolibrary.org/obo/ECO_0001053 |
---|---|
Super-classes |
obo:ECO_0005517c |
Sub-classes |
obo:ECO_0007390c obo:ECO_0001186c |
URI | http://purl.obolibrary.org/obo/ECO_0001054 |
---|---|
Super-classes |
obo:ECO_0000040c |
Sub-classes |
obo:ECO_0001188c obo:ECO_0007391c |
URI | http://purl.obolibrary.org/obo/ECO_0001055 |
---|---|
Super-classes |
obo:ECO_0005517c |
Sub-classes |
obo:ECO_0001189c obo:ECO_0007392c |
URI | http://purl.obolibrary.org/obo/ECO_0001056 |
---|---|
Description |
This term was made obsolete for a couple of reasons: the def. doesn’t make sense as the suggested means of mutagenesis fail to introduce exogenous DNA (it is a child of genetic transformation evidence) and the def. is too much like random mutagenesis evidence. |
URI | http://purl.obolibrary.org/obo/ECO_0001057 |
---|---|
Super-classes |
obo:ECO_0001546c |
Sub-classes |
obo:ECO_0001190c obo:ECO_0007393c |
URI | http://purl.obolibrary.org/obo/ECO_0001058 |
---|---|
Super-classes |
obo:ECO_0001547c |
Sub-classes |
obo:ECO_0007394c obo:ECO_0001191c |
URI | http://purl.obolibrary.org/obo/ECO_0001059 |
---|---|
Super-classes |
obo:ECO_0001552c |
Sub-classes |
obo:ECO_0001196c obo:ECO_0007399c |
URI | http://purl.obolibrary.org/obo/ECO_0001060 |
---|---|
Super-classes |
obo:ECO_0001548c |
Sub-classes |
obo:ECO_0001192c obo:ECO_0007395c |
URI | http://purl.obolibrary.org/obo/ECO_0001061 |
---|---|
Super-classes |
obo:ECO_0001549c |
Sub-classes |
obo:ECO_0001193c obo:ECO_0007396c |
URI | http://purl.obolibrary.org/obo/ECO_0001062 |
---|---|
Super-classes |
obo:ECO_0001550c |
Sub-classes |
obo:ECO_0007397c obo:ECO_0001194c |
URI | http://purl.obolibrary.org/obo/ECO_0001063 |
---|---|
Super-classes |
obo:ECO_0001551c |
Sub-classes |
obo:ECO_0007398c obo:ECO_0001195c |
URI | http://purl.obolibrary.org/obo/ECO_0001064 |
---|---|
Super-classes |
obo:ECO_0001553c |
Sub-classes |
obo:ECO_0007400c obo:ECO_0001197c |
URI | http://purl.obolibrary.org/obo/ECO_0001065 |
---|---|
Super-classes |
obo:ECO_0001554c |
Sub-classes |
obo:ECO_0000086c obo:ECO_0001198c obo:ECO_0007401c obo:ECO_0000077c obo:ECO_0000069c |
URI | http://purl.obolibrary.org/obo/ECO_0001066 |
---|---|
Super-classes |
obo:ECO_0001555c |
Sub-classes |
obo:ECO_0007402c obo:ECO_0001199c |
URI | http://purl.obolibrary.org/obo/ECO_0001067 |
---|---|
Super-classes |
obo:ECO_0001556c |
Sub-classes |
obo:ECO_0007403c obo:ECO_0001200c |
URI | http://purl.obolibrary.org/obo/ECO_0001068 |
---|---|
Super-classes |
obo:ECO_0001558c |
Sub-classes |
obo:ECO_0001202c obo:ECO_0007405c |
URI | http://purl.obolibrary.org/obo/ECO_0001069 |
---|---|
Super-classes |
obo:ECO_0001557c |
Sub-classes |
obo:ECO_0001201c obo:ECO_0007404c |
URI | http://purl.obolibrary.org/obo/ECO_0001070 |
---|---|
Super-classes |
obo:ECO_0001559c |
Sub-classes |
obo:ECO_0007406c obo:ECO_0001203c |
URI | http://purl.obolibrary.org/obo/ECO_0001071 |
---|---|
Super-classes |
obo:ECO_0000168c |
Sub-classes |
obo:ECO_0007407c obo:ECO_0001204c |
URI | http://purl.obolibrary.org/obo/ECO_0001072 |
---|---|
Super-classes |
obo:ECO_0001561c |
Sub-classes |
obo:ECO_0001205c obo:ECO_0007408c |
URI | http://purl.obolibrary.org/obo/ECO_0001073 |
---|---|
Super-classes |
obo:ECO_0001562c |
Sub-classes |
obo:ECO_0001206c obo:ECO_0007409c |
URI | http://purl.obolibrary.org/obo/ECO_0001074 |
---|---|
Super-classes |
obo:ECO_0001546c |
Sub-classes |
obo:ECO_0007410c obo:ECO_0001207c |
URI | http://purl.obolibrary.org/obo/ECO_0001075 |
---|---|
Super-classes |
obo:ECO_0001547c |
Sub-classes |
obo:ECO_0001208c obo:ECO_0007411c |
URI | http://purl.obolibrary.org/obo/ECO_0001076 |
---|---|
Super-classes |
obo:ECO_0001548c |
Sub-classes |
obo:ECO_0007412c obo:ECO_0001209c |
URI | http://purl.obolibrary.org/obo/ECO_0001077 |
---|---|
Super-classes |
obo:ECO_0001549c |
Sub-classes |
obo:ECO_0001210c obo:ECO_0007413c |
URI | http://purl.obolibrary.org/obo/ECO_0001078 |
---|---|
Super-classes |
obo:ECO_0001550c |
Sub-classes |
obo:ECO_0007414c obo:ECO_0001211c |
URI | http://purl.obolibrary.org/obo/ECO_0001079 |
---|---|
Super-classes |
obo:ECO_0001552c |
Sub-classes |
obo:ECO_0001213c obo:ECO_0007416c |
URI | http://purl.obolibrary.org/obo/ECO_0001080 |
---|---|
Super-classes |
obo:ECO_0001551c |
Sub-classes |
obo:ECO_0007415c obo:ECO_0001212c |
URI | http://purl.obolibrary.org/obo/ECO_0001081 |
---|---|
Super-classes |
obo:ECO_0001553c |
Sub-classes |
obo:ECO_0007417c obo:ECO_0001214c |
URI | http://purl.obolibrary.org/obo/ECO_0001082 |
---|---|
Super-classes |
obo:ECO_0001554c |
Sub-classes |
obo:ECO_0001215c obo:ECO_0007418c |
URI | http://purl.obolibrary.org/obo/ECO_0001083 |
---|---|
Super-classes |
obo:ECO_0001555c |
Sub-classes |
obo:ECO_0001216c obo:ECO_0007419c |
URI | http://purl.obolibrary.org/obo/ECO_0001084 |
---|---|
Super-classes |
obo:ECO_0001556c |
Sub-classes |
obo:ECO_0001217c obo:ECO_0007420c |
URI | http://purl.obolibrary.org/obo/ECO_0001085 |
---|---|
Super-classes |
obo:ECO_0001558c |
Sub-classes |
obo:ECO_0001218c obo:ECO_0007421c |
URI | http://purl.obolibrary.org/obo/ECO_0001086 |
---|---|
Super-classes |
obo:ECO_0001559c |
Sub-classes |
obo:ECO_0007422c obo:ECO_0001219c |
URI | http://purl.obolibrary.org/obo/ECO_0001087 |
---|---|
Super-classes |
obo:ECO_0000168c |
Sub-classes |
obo:ECO_0007423c obo:ECO_0001220c |
URI | http://purl.obolibrary.org/obo/ECO_0001088 |
---|---|
Super-classes |
obo:ECO_0001561c |
Restrictions |
obo:OBI_0000312op some obo:OBI_0000966c obo:OBI_0000312op some (obo:OBI_0000070c and n91afa4cc91624519895f2f4dded8ec52b1052c) obo:IAO_0000136op some obo:GO_0006412c |
Sub-classes |
obo:ECO_0007424c obo:ECO_0001221c |
URI | http://purl.obolibrary.org/obo/ECO_0001089 |
---|---|
Super-classes |
obo:ECO_0001562c |
Sub-classes |
obo:ECO_0001222c obo:ECO_0007425c |
URI | http://purl.obolibrary.org/obo/ECO_0001090 |
---|---|
Super-classes |
obo:ECO_0005027c |
Restrictions | obo:OBI_0000312op some (obo:OBI_0000070< |