@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix : <http://purl.obolibrary.org/obo/obib.owl#> .
@prefix dc: <http://purl.org/dc/elements/1.1/> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xml: <http://www.w3.org/XML/1998/namespace> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix swrl: <http://www.w3.org/2003/11/swrl#> .
@prefix swrlb: <http://www.w3.org/2003/11/swrlb#> .
@prefix terms: <http://purl.org/dc/terms/> .
@prefix protege: <http://protege.stanford.edu/plugins/owl/protege#> .
@prefix oboInOwl: <http://www.geneontology.org/formats/oboInOwl#> .
@prefix apollo_sv: <http://purl.obolibrary.org/obo/apollo_sv.owl/> .

protege:defaultLanguage
    a owl:AnnotationProperty .

obo:APOLLO_SV_00000032
    obo:IAO_0000115 "A measurement datum that is the output of counting."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/apollo_sv.owl> ;
    obo:IAO_0000600 "A measurement datum that is the output of counting."@en ;
    apollo_sv:APOLLO_SV_0000040 "count"^^xsd:string ;
    a owl:Class ;
    rdfs:label "count"@en ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:APOLLO_SV_00000033
    obo:IAO_0000115 "The planned process of finding the number of elements in a finite set of objects."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Counting" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/apollo_sv.owl> ;
    obo:IAO_0000600 "The planned process of finding the number of elements in a finite set of objects."@en ;
    a owl:Class ;
    rdfs:label "counting"@en ;
    rdfs:subClassOf obo:OBI_0000011 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000011
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000299 ;
                owl:someValuesFrom obo:APOLLO_SV_00000032
            ]
        )
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:APOLLO_SV_00000032
    ] .

obo:APOLLO_SV_00000085
    obo:IAO_0000111 "age structure data set"@en ;
    obo:IAO_0000115 "A data set consisting of measurements of age organized in age brackets." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/apollo_sv.owl> ;
    obo:IAO_0000600 "A data set consisting of measurements of age organized in age brackets." ;
    a owl:Class ;
    rdfs:label "age data in age brackets data set"@en ;
    rdfs:subClassOf obo:IAO_0000100 .

obo:APOLLO_SV_00000496
    obo:IAO_0000115 "An identifier curated by ORCID, Inc. to denote some academic author."@en ;
    obo:IAO_0000117 "Matthew Diller", "William R. Hogan" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/apollo_sv.owl> ;
    obo:IAO_0000600 "An identifier curated by ORCID, Inc. to denote some academic author."@en ;
    apollo_sv:APOLLO_SV_0000040 "orcId"^^xsd:string ;
    a owl:Class ;
    rdfs:label "ORCID"@en ;
    rdfs:subClassOf obo:IAO_0020000 .

obo:BFO_0000001
    obo:BFO_0000179 "entity" ;
    obo:BFO_0000180 "Entity" ;
    obo:IAO_0000112 "Julius Caesar"@en, "Verdi’s Requiem"@en, "the Second World War"@en, "your body mass index"@en ;
    obo:IAO_0000116 "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81"@en, "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"@en ;
    obo:IAO_0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])"@en ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "entity"@en ;
    rdfs:subClassOf owl:Thing .

obo:BFO_0000002
    obo:BFO_0000179 "continuant" ;
    obo:BFO_0000180 "Continuant" ;
    obo:IAO_0000115 "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ;
    obo:IAO_0000116 "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240"@en, "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants"@en ;
    obo:IAO_0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])"@en ;
    obo:IAO_0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])"@en, "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])"@en, "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])"@en ;
    obo:IAO_0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] ", "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] ", "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] ", "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "continuant"@en ;
    rdfs:subClassOf obo:BFO_0000001 ;
    owl:disjointWith obo:BFO_0000003, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000050 ;
        owl:someValuesFrom obo:BFO_0000003
    ] .

obo:BFO_0000003
    obo:BFO_0000179 "occurrent" ;
    obo:BFO_0000180 "Occurrent" ;
    obo:IAO_0000115 "An entity that has temporal parts and that happens, unfolds or develops through time."@en ;
    obo:IAO_0000116 "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region"@en, "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players."@en, "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process."@en, "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." ;
    obo:IAO_0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])"@en ;
    obo:IAO_0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])"@en, "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] ", "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "occurrent"@en ;
    rdfs:subClassOf obo:BFO_0000001 ;
    owl:disjointWith [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000050 ;
        owl:someValuesFrom obo:BFO_0000002
    ] .

obo:BFO_0000004
    obo:BFO_0000179 "ic" ;
    obo:BFO_0000180 "IndependentContinuant" ;
    obo:IAO_0000112 "a chair"@en, "a heart"@en, "a leg"@en, "a molecule"@en, "a spatial region"@en, "an atom"@en, "an orchestra."@en, "an organism"@en, "the bottom right portion of a human torso"@en, "the interior of your mouth"@en ;
    obo:IAO_0000115 "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything."@en, "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ;
    obo:IAO_0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])"@en, "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])"@en ;
    obo:IAO_0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] ", "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] ", "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "independent continuant"@en ;
    rdfs:subClassOf obo:BFO_0000002 ;
    owl:disjointWith obo:BFO_0000020, obo:BFO_0000031 .

obo:BFO_0000006
    obo:BFO_0000179 "s-region" ;
    obo:BFO_0000180 "SpatialRegion" ;
    obo:IAO_0000116 "BFO 2 Reference: Spatial regions do not participate in processes."@en, "Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional."@en ;
    obo:IAO_0000600 "A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])"@en ;
    obo:IAO_0000601 "All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])"@en ;
    obo:IAO_0000602 "(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] ", "(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "spatial region"@en ;
    rdfs:subClassOf obo:BFO_0000141 ;
    owl:disjointWith obo:BFO_0000029, obo:BFO_0000140 .

obo:BFO_0000008
    obo:BFO_0000179 "t-region" ;
    obo:BFO_0000180 "TemporalRegion" ;
    obo:IAO_0000116 "Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional"@en ;
    obo:IAO_0000600 "A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])"@en ;
    obo:IAO_0000601 "All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])"@en, "Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])"@en ;
    obo:IAO_0000602 "(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] ", "(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] ", "(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "temporal region"@en ;
    rdfs:subClassOf obo:BFO_0000003 ;
    owl:disjointWith obo:BFO_0000011, obo:BFO_0000015, obo:BFO_0000035 .

obo:BFO_0000009
    obo:BFO_0000179 "2d-s-region" ;
    obo:BFO_0000180 "TwoDimensionalSpatialRegion" ;
    obo:IAO_0000112 "an infinitely thin plane in space."@en, "the surface of a sphere-shaped part of space"@en ;
    obo:IAO_0000600 "A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "two-dimensional spatial region"@en ;
    rdfs:subClassOf obo:BFO_0000006 ;
    owl:disjointWith obo:BFO_0000028 .

obo:BFO_0000011
    obo:BFO_0000179 "st-region" ;
    obo:BFO_0000180 "SpatiotemporalRegion" ;
    obo:IAO_0000112 "the spatiotemporal region occupied by a human life"@en, "the spatiotemporal region occupied by a process of cellular meiosis."@en, "the spatiotemporal region occupied by the development of a cancer tumor"@en ;
    obo:IAO_0000600 "A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])"@en ;
    obo:IAO_0000601 "All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])"@en, "Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])"@en, "Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])"@en, "Every spatiotemporal region occupies_spatiotemporal_region itself."@en, "Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])"@en ;
    obo:IAO_0000602 "(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] ", "(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] ", "(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] ", "(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] ", "(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "spatiotemporal region"@en ;
    rdfs:subClassOf obo:BFO_0000003 .

obo:BFO_0000015
    obo:BFO_0000179 "process" ;
    obo:BFO_0000180 "Process" ;
    obo:IAO_0000112 "a process of cell-division, \\ a beating of the heart"@en, "a process of meiosis"@en, "a process of sleeping"@en, "the course of a disease"@en, "the flight of a bird"@en, "the life of an organism"@en, "your process of aging."@en ;
    obo:IAO_0000115 "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t."@en, "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ;
    obo:IAO_0000116 "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)"@en ;
    obo:IAO_0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "process"@en ;
    rdfs:subClassOf obo:BFO_0000003 .

obo:BFO_0000016
    obo:BFO_0000179 "disposition" ;
    obo:BFO_0000180 "Disposition" ;
    obo:IAO_0000112 "an atom of element X has the disposition to decay to an atom of element Y"@en, "certain people have a predisposition to colon cancer"@en, "children are innately disposed to categorize objects in certain ways."@en, "the cell wall is disposed to filter chemicals in endocytosis and exocytosis"@en ;
    obo:IAO_0000116 "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type."@en ;
    obo:IAO_0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])"@en ;
    obo:IAO_0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])"@en ;
    obo:IAO_0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] ", "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "disposition"@en ;
    rdfs:subClassOf obo:BFO_0000017 ;
    owl:disjointWith obo:BFO_0000023 .

obo:BFO_0000017
    obo:BFO_0000179 "realizable" ;
    obo:BFO_0000180 "RealizableEntity" ;
    obo:IAO_0000112 "the disposition of this piece of metal to conduct electricity."@en, "the disposition of your blood to coagulate"@en, "the function of your reproductive organs"@en, "the role of being a doctor"@en, "the role of this boundary to delineate where Utah and Colorado meet"@en ;
    obo:IAO_0000115 "A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ;
    obo:IAO_0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])"@en ;
    obo:IAO_0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])"@en ;
    obo:IAO_0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] ", "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "realizable entity"@en ;
    rdfs:subClassOf obo:BFO_0000020 ;
    owl:disjointWith obo:BFO_0000019 .

obo:BFO_0000018
    obo:BFO_0000179 "0d-s-region" ;
    obo:BFO_0000180 "ZeroDimensionalSpatialRegion" ;
    obo:IAO_0000600 "A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "zero-dimensional spatial region"@en ;
    rdfs:subClassOf obo:BFO_0000006 ;
    owl:disjointWith obo:BFO_0000028 .

obo:BFO_0000019
    obo:BFO_0000179 "quality" ;
    obo:BFO_0000180 "Quality" ;
    obo:IAO_0000112 "the ambient temperature of this portion of air"@en, "the color of a tomato"@en, "the length of the circumference of your waist"@en, "the mass of this piece of gold."@en, "the shape of your nose"@en, "the shape of your nostril"@en ;
    obo:IAO_0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])"@en ;
    obo:IAO_0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] ", "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "quality"@en ;
    rdfs:subClassOf obo:BFO_0000020 .

obo:BFO_0000020
    obo:BFO_0000179 "sdc" ;
    obo:BFO_0000180 "SpecificallyDependentContinuant" ;
    obo:IAO_0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key"@en, "of one-sided specifically dependent continuants: the mass of this tomato"@en, "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates."@en, "the disposition of this fish to decay"@en, "the function of this heart: to pump blood"@en, "the mutual dependence of proton donors and acceptors in chemical reactions [79"@en, "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction"@en, "the pink color of a medium rare piece of grilled filet mignon at its center"@en, "the role of being a doctor"@en, "the shape of this hole."@en, "the smell of this portion of mozzarella"@en ;
    obo:IAO_0000115 "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en, "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ;
    obo:IAO_0000116 "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc."@en ;
    obo:IAO_0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "specifically dependent continuant"@en ;
    rdfs:subClassOf obo:BFO_0000002 ;
    owl:disjointWith obo:BFO_0000031 .

obo:BFO_0000023
    obo:BFO_0000179 "role" ;
    obo:BFO_0000180 "Role" ;
    obo:IAO_0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married."@en, "the priest role"@en, "the role of a boundary to demarcate two neighboring administrative territories"@en, "the role of a building in serving as a military target"@en, "the role of a stone in marking a property boundary"@en, "the role of subject in a clinical trial"@en, "the student role"@en ;
    obo:IAO_0000115 "A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts."@en ;
    obo:IAO_0000116 "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals –  professor, sergeant, nurse – only during certain phases in their lives."@en ;
    obo:IAO_0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "role"@en ;
    rdfs:subClassOf obo:BFO_0000017 .

obo:BFO_0000024
    obo:BFO_0000179 "fiat-object-part" ;
    obo:BFO_0000180 "FiatObjectPart" ;
    obo:IAO_0000112 "or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29"@en, "the FMA:regional parts of an intact human body."@en, "the Western hemisphere of the Earth"@en, "the division of the brain into regions"@en, "the division of the planet into hemispheres"@en, "the dorsal and ventral surfaces of the body"@en, "the upper and lower lobes of the left lung"@en ;
    obo:IAO_0000116 "BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions"@en ;
    obo:IAO_0000600 "b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of  c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])"@en ;
    obo:IAO_0000602 "(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "fiat object part"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:BFO_0000026
    obo:BFO_0000179 "1d-s-region" ;
    obo:BFO_0000180 "OneDimensionalSpatialRegion" ;
    obo:IAO_0000112 "an edge of a cube-shaped portion of space."@en ;
    obo:IAO_0000600 "A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "one-dimensional spatial region"@en ;
    rdfs:subClassOf obo:BFO_0000006 ;
    owl:disjointWith obo:BFO_0000028 .

obo:BFO_0000027
    obo:BFO_0000179 "object-aggregate" ;
    obo:BFO_0000180 "ObjectAggregate" ;
    obo:IAO_0000112 "a collection of cells in a blood biobank."@en, "a swarm of bees is an aggregate of members who are linked together through natural bonds"@en, "a symphony orchestra"@en, "an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)"@en, "defined by fiat: the aggregate of members of an organization"@en, "defined through physical attachment: the aggregate of atoms in a lump of granite"@en, "defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container"@en, "defined via attributive delimitations such as: the patients in this hospital"@en, "the aggregate of bearings in a constant velocity axle joint"@en, "the aggregate of blood cells in your body"@en, "the nitrogen atoms in the atmosphere"@en, "the restaurants in Palo Alto"@en, "your collection of Meissen ceramic plates."@en ;
    obo:IAO_0000116 "An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects ", "BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee)."@en ;
    obo:IAO_0000119 "ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158." ;
    obo:IAO_0000600 "b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])"@en ;
    obo:IAO_0000602 "(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "object aggregate"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:BFO_0000028
    obo:BFO_0000179 "3d-s-region" ;
    obo:BFO_0000180 "ThreeDimensionalSpatialRegion" ;
    obo:IAO_0000112 "a cube-shaped region of space"@en, "a sphere-shaped region of space,"@en ;
    obo:IAO_0000600 "A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "three-dimensional spatial region"@en ;
    rdfs:subClassOf obo:BFO_0000006 .

obo:BFO_0000029
    obo:BFO_0000179 "site" ;
    obo:BFO_0000180 "Site" ;
    obo:IAO_0000112 "Manhattan Canyon)"@en, "a hole in the interior of a portion of cheese"@en, "a rabbit hole"@en, "an air traffic control region defined in the airspace above an airport"@en, "the Grand Canyon"@en, "the Piazza San Marco"@en, "the cockpit of an aircraft"@en, "the hold of a ship"@en, "the interior of a kangaroo pouch"@en, "the interior of the trunk of your car"@en, "the interior of your bedroom"@en, "the interior of your office"@en, "the interior of your refrigerator"@en, "the lumen of your gut"@en, "your left nostril (a fiat part – the opening – of your left nasal cavity)"@en ;
    obo:IAO_0000600 "b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])"@en ;
    obo:IAO_0000602 "(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "site"@en ;
    rdfs:subClassOf obo:BFO_0000141 .

obo:BFO_0000030
    obo:BFO_0000179 "object" ;
    obo:BFO_0000180 "Object" ;
    obo:IAO_0000112 "atom"@en, "cell"@en, "cells and organisms"@en, "engineered artifacts"@en, "grain of sand"@en, "molecule"@en, "organelle"@en, "organism"@en, "planet"@en, "solid portions of matter"@en, "star"@en ;
    obo:IAO_0000116 "BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting."@en, "BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below)."@en, "BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47"@en, "BFO 2 Reference: an object is a maximal causally unified material entity"@en, "BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74"@en ;
    obo:IAO_0000600 "b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])"@en ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "object"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:BFO_0000031
    obo:BFO_0000179 "gdc" ;
    obo:BFO_0000180 "GenericallyDependentContinuant" ;
    obo:IAO_0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity."@en, "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop"@en, "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule."@en ;
    obo:IAO_0000115 "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en, "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en ;
    obo:IAO_0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "generically dependent continuant"@en ;
    rdfs:subClassOf obo:BFO_0000002 .

obo:BFO_0000034
    obo:BFO_0000179 "function" ;
    obo:BFO_0000180 "Function" ;
    obo:IAO_0000112 "the function of a hammer to drive in nails"@en, "the function of a heart pacemaker to regulate the beating of a heart through electricity"@en, "the function of amylase in saliva to break down starch into sugar"@en ;
    obo:IAO_0000116 "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc."@en ;
    obo:IAO_0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "function"@en ;
    rdfs:subClassOf obo:BFO_0000016 .

obo:BFO_0000035
    obo:BFO_0000179 "p-boundary" ;
    obo:BFO_0000180 "ProcessBoundary" ;
    obo:IAO_0000112 "the boundary between the 2nd and 3rd year of your life."@en ;
    obo:IAO_0000115 "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ;
    obo:IAO_0000601 "Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])"@en ;
    obo:IAO_0000602 "(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] ", "(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "process boundary"@en ;
    rdfs:subClassOf obo:BFO_0000003 .

obo:BFO_0000038
    obo:BFO_0000179 "1d-t-region" ;
    obo:BFO_0000180 "OneDimensionalTemporalRegion" ;
    obo:IAO_0000112 "the temporal region during which a process occurs."@en ;
    obo:IAO_0000116 "BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks)."@en ;
    obo:IAO_0000600 "A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "one-dimensional temporal region"@en ;
    rdfs:subClassOf obo:BFO_0000008 ;
    owl:disjointWith obo:BFO_0000148 .

obo:BFO_0000040
    obo:BFO_0000179 "material" ;
    obo:BFO_0000180 "MaterialEntity" ;
    obo:IAO_0000112 "a flame"@en, "a forest fire"@en, "a human being"@en, "a hurricane"@en, "a photon"@en, "a puff of smoke"@en, "a sea wave"@en, "a tornado"@en, "an aggregate of human beings."@en, "an energy wave"@en, "an epidemic"@en, "the undetached arm of a human being"@en ;
    obo:IAO_0000115 "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ;
    obo:IAO_0000116 "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60"@en, "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity."@en, "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here."@en ;
    obo:IAO_0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])"@en ;
    obo:IAO_0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])"@en, "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])"@en ;
    obo:IAO_0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] ", "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] ", "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "material entity"@en ;
    rdfs:subClassOf obo:BFO_0000004 ;
    owl:disjointWith obo:BFO_0000141 .

obo:BFO_0000050
    obo:IAO_0000111 "is part of"@en ;
    obo:IAO_0000112 "my brain is part of my body (continuant parthood, two material entities)"@en, "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"@en, "this day is part of this year (occurrent parthood)"@en ;
    obo:IAO_0000115 "a core relation that holds between a part and its whole"@en ;
    obo:IAO_0000116 "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."@en, "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en, """Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)

A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."""@en ;
    obo:IAO_0000118 "part_of"@en ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:ObjectProperty, owl:TransitiveProperty ;
    rdfs:label "part of"@en ;
    rdfs:seeAlso "http://www.obofoundry.org/ro/#OBO_REL:part_of" ;
    owl:inverseOf obo:BFO_0000051 .

obo:BFO_0000051
    obo:IAO_0000111 "has part"@en ;
    obo:IAO_0000112 "my body has part my brain (continuant parthood, two material entities)"@en, "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"@en, "this year has part this day (occurrent parthood)"@en ;
    obo:IAO_0000115 "a core relation that holds between a whole and its part"@en ;
    obo:IAO_0000116 "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."@en, "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en, """Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)

A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."""@en ;
    obo:IAO_0000118 "has_part"@en ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:ObjectProperty, owl:TransitiveProperty ;
    rdfs:label "has part"@en .

obo:BFO_0000054
    obo:IAO_0000111 "realized in"@en ;
    obo:IAO_0000112 "this disease is realized in this disease course"@en, "this fragility is realized in this shattering"@en, "this investigator role is realized in this investigation"@en ;
    obo:IAO_0000118 "is realized by"@en, "realized_in"@en ;
    obo:IAO_0000600 "[copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])"@en ;
    a owl:ObjectProperty ;
    rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
    rdfs:domain obo:BFO_0000017 ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "realized in"@en ;
    rdfs:range obo:BFO_0000015 ;
    owl:inverseOf obo:BFO_0000055 .

obo:BFO_0000055
    obo:IAO_0000111 "realizes"@en ;
    obo:IAO_0000112 "this disease course realizes this disease"@en, "this investigation realizes this investigator role"@en, "this shattering realizes this fragility"@en ;
    obo:IAO_0000600 "to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])"@en ;
    a owl:ObjectProperty ;
    rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ;
    rdfs:domain obo:BFO_0000015 ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "realizes"@en ;
    rdfs:range obo:BFO_0000017 .

obo:BFO_0000062
    obo:IAO_0000115 "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
    obo:IAO_0000118 "is preceded by"@en, "preceded_by"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty, owl:TransitiveProperty ;
    rdfs:label "preceded by"@en ;
    rdfs:subPropertyOf obo:RO_0002222 .

obo:BFO_0000063
    obo:IAO_0000115 "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty, owl:TransitiveProperty ;
    rdfs:label "precedes"@en ;
    rdfs:subPropertyOf obo:RO_0002222 .

obo:BFO_0000066
    obo:IAO_0000111 "occurs in"@en ;
    obo:IAO_0000115 "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
    obo:IAO_0000118 "occurs_in"@en, "unfolds in"@en, "unfolds_in"@en ;
    a owl:ObjectProperty ;
    rdfs:comment "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant" ;
    rdfs:domain obo:BFO_0000003 ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "occurs in"@en ;
    rdfs:range obo:BFO_0000004 ;
    owl:inverseOf obo:BFO_0000067 ;
    owl:propertyChainAxiom (obo:BFO_0000050
        obo:BFO_0000066
    ), (obo:BFO_0000066
        obo:BFO_0000050
    ) .

obo:BFO_0000067
    obo:IAO_0000111 "site of"@en ;
    obo:IAO_0000115 "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ;
    a owl:ObjectProperty ;
    rdfs:comment "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant" ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "contains process"@en .

obo:BFO_0000140
    obo:BFO_0000179 "cf-boundary" ;
    obo:BFO_0000180 "ContinuantFiatBoundary" ;
    obo:IAO_0000115 "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en ;
    obo:IAO_0000116 "BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions."@en, "BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29"@en, "Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions."@en ;
    obo:IAO_0000601 "Every continuant fiat boundary is located at some spatial region at every time at which it exists"@en ;
    obo:IAO_0000602 "(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "continuant fiat boundary"@en ;
    rdfs:subClassOf obo:BFO_0000141 .

obo:BFO_0000141
    obo:BFO_0000179 "immaterial" ;
    obo:BFO_0000180 "ImmaterialEntity" ;
    obo:IAO_0000116 "BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10"@en ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "immaterial entity"@en ;
    rdfs:subClassOf obo:BFO_0000004 .

obo:BFO_0000142
    obo:BFO_0000179 "1d-cf-boundary" ;
    obo:BFO_0000180 "OneDimensionalContinuantFiatBoundary" ;
    obo:IAO_0000112 "The Equator"@en, "all geopolitical boundaries"@en, "all lines of latitude and longitude"@en, "the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin."@en, "the median sulcus of your tongue"@en ;
    obo:IAO_0000600 "a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])"@en ;
    obo:IAO_0000602 "(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "one-dimensional continuant fiat boundary"@en ;
    rdfs:subClassOf obo:BFO_0000140 ;
    owl:disjointWith obo:BFO_0000146, obo:BFO_0000147 .

obo:BFO_0000144
    obo:BFO_0000179 "process-profile" ;
    obo:BFO_0000180 "ProcessProfile" ;
    obo:IAO_0000112 "On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels"@en, "One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from   rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance."@en, "The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on."@en ;
    obo:IAO_0000115 "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ;
    obo:IAO_0000600 "b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])"@en ;
    obo:IAO_0000602 "(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] ", "(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "process profile"@en ;
    rdfs:subClassOf obo:BFO_0000015 ;
    owl:disjointWith obo:BFO_0000182 .

obo:BFO_0000145
    obo:BFO_0000179 "r-quality" ;
    obo:BFO_0000180 "RelationalQuality" ;
    obo:IAO_0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married."@en, "a marriage bond, an instance of requited love, an obligation between one person and another."@en ;
    obo:IAO_0000115 "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en ;
    obo:IAO_0000602 "(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "relational quality"@en ;
    rdfs:subClassOf obo:BFO_0000019 .

obo:BFO_0000146
    obo:BFO_0000179 "2d-cf-boundary" ;
    obo:BFO_0000180 "TwoDimensionalContinuantFiatBoundary" ;
    obo:IAO_0000600 "a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])"@en ;
    obo:IAO_0000602 "(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "two-dimensional continuant fiat boundary"@en ;
    rdfs:subClassOf obo:BFO_0000140 .

obo:BFO_0000147
    obo:BFO_0000179 "0d-cf-boundary" ;
    obo:BFO_0000180 "ZeroDimensionalContinuantFiatBoundary" ;
    obo:IAO_0000112 "the geographic North Pole"@en, "the point of origin of some spatial coordinate system."@en, "the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet"@en ;
    obo:IAO_0000116 "zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona."@en ;
    obo:IAO_0000600 "a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])"@en ;
    obo:IAO_0000602 "(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "zero-dimensional continuant fiat boundary"@en ;
    rdfs:subClassOf obo:BFO_0000140 .

obo:BFO_0000148
    obo:BFO_0000179 "0d-t-region" ;
    obo:BFO_0000180 "ZeroDimensionalTemporalRegion" ;
    obo:IAO_0000112 "a temporal region that is occupied by a process boundary"@en, "right now"@en, "the moment at which a child is born"@en, "the moment at which a finger is detached in an industrial accident"@en, "the moment of death."@en ;
    obo:IAO_0000118 "temporal instant."@en ;
    obo:IAO_0000600 "A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])"@en ;
    obo:IAO_0000602 "(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] " ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "zero-dimensional temporal region"@en ;
    rdfs:subClassOf obo:BFO_0000008 .

obo:BFO_0000156
    obo:BFO_0000179 "span-of" ;
    obo:BFO_0000180 "spanOf" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/bfo/2012-07-20/bfo.owl> ;
    obo:IAO_0000600 "[copied from inverse property 'occupies temporal region'] p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001])" ;
    a owl:ObjectProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo/2012-07-20/bfo.owl> ;
    rdfs:label "has temporal occupant"@en ;
    rdfs:range obo:BFO_0000003 .

obo:BFO_0000179
    obo:IAO_0000115 "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ;
    obo:IAO_0000232 "Really of interest to developers only"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "BFO OWL specification label"@en ;
    rdfs:subPropertyOf rdfs:label .

obo:BFO_0000180
    obo:IAO_0000115 "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ;
    obo:IAO_0000119 "Person:Alan Ruttenberg" ;
    obo:IAO_0000232 "Really of interest to developers only"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "BFO CLIF specification label"@en ;
    rdfs:subPropertyOf rdfs:label .

obo:BFO_0000182
    obo:BFO_0000179 "history" ;
    obo:BFO_0000180 "History" ;
    obo:IAO_0000600 "A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])"@en ;
    a owl:Class ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo.owl> ;
    rdfs:label "history"@en ;
    rdfs:subClassOf obo:BFO_0000015 .

obo:BFO_0000184
    obo:BFO_0000179 "history-of" ;
    obo:BFO_0000180 "historyOf" ;
    obo:IAO_0000115 "[copied from inverse property 'has history'] b has_history c iff c history_of b [XXX-001" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/bfo/2012-07-20/bfo.owl> ;
    obo:IAO_0000600 "b history_of c if c is a material entity or site and b is a history that is the unique history of cAxiom: if b history_of c and b history_of d then c=d [XXX-001"@en ;
    a owl:FunctionalProperty, owl:InverseFunctionalProperty, owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000015 ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo/2012-07-20/bfo.owl> ;
    rdfs:label "history of"@en ;
    rdfs:range obo:BFO_0000040 ;
    rdfs:subPropertyOf obo:BFO_0000066 ;
    owl:inverseOf obo:BFO_0000185 .

obo:BFO_0000185
    obo:BFO_0000179 "has-history" ;
    obo:BFO_0000180 "hasHistory" ;
    obo:IAO_0000115 "b has_history c iff c history_of b [XXX-001"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/bfo/2012-07-20/bfo.owl> ;
    obo:IAO_0000600 "[copied from inverse property 'history of'] b history_of c if c is a material entity or site and b is a history that is the unique history of cAxiom: if b history_of c and b history_of d then c=d [XXX-001" ;
    a owl:FunctionalProperty, owl:InverseFunctionalProperty, owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000040 ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/bfo/2012-07-20/bfo.owl> ;
    rdfs:label "has history"@en ;
    rdfs:range obo:BFO_0000015 ;
    rdfs:subPropertyOf obo:BFO_0000067 .

obo:CHEBI_119915
    obo:IAO_0000115 "A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid."^^xsd:string ;
    obo:IAO_0000118 "N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "fentanyl"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_16236
    obo:IAO_0000115 "A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group."^^xsd:string ;
    obo:IAO_0000118 "ETHANOL"^^xsd:string, "Ethanol"^^xsd:string, "ethanol"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "ethanol"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_30879 .

obo:CHEBI_16670
    obo:IAO_0000115 "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc."^^xsd:string ;
    obo:IAO_0000118 "Peptide"^^xsd:string, "peptides"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "peptide"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_33839 .

obo:CHEBI_16842
    obo:IAO_0000115 "An aldehyde resulting from the formal oxidation of methanol."^^xsd:string ;
    obo:IAO_0000118 "FORMALDEHYDE"^^xsd:string, "Formaldehyde"^^xsd:string, "formaldehyde"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "formaldehyde"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_16991
    obo:IAO_0000115 "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms."^^xsd:string ;
    obo:IAO_0000118 "Deoxyribonucleic acid"^^xsd:string, "deoxyribonucleic acids"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "deoxyribonucleic acid"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_33696 .

obo:CHEBI_17045
    obo:IAO_0000115 "A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream."^^xsd:string ;
    obo:IAO_0000118 "Dinitrogen oxide"^^xsd:string, "dinitrogen oxide"^^xsd:string, "oxidodinitrogen(N--N)"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "dinitrogen oxide"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_17303
    obo:IAO_0000115 "A morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy)."^^xsd:string ;
    obo:IAO_0000118 "17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol"^^xsd:string, "Morphine"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "morphine"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_18723
    obo:IAO_0000115 "A racemate composed of equimolar amounts of (R)- and (S)-nicotine."^^xsd:string ;
    obo:IAO_0000118 "rac-3-(1-methylpyrrolidin-2-yl)pyridine"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "nicotine"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_23367
    obo:IAO_0000115 "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity."^^xsd:string ;
    obo:IAO_0000118 "molecular entity"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "molecular entity"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:CHEBI_27338
    obo:IAO_0000118 "xylene"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "xylene"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_30879
    obo:IAO_0000115 "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom."^^xsd:string ;
    obo:IAO_0000118 "Alcohol"^^xsd:string, "alcohols"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "alcohol"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_3215
    obo:IAO_0000115 "A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic."^^xsd:string ;
    obo:IAO_0000118 "Bupivacaine"^^xsd:string, "rac-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "bupivacaine"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_33250
    obo:IAO_0000115 "A chemical entity constituting the smallest component of an element having the chemical properties of the element."^^xsd:string ;
    obo:IAO_0000118 "atom"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "atom"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:CHEBI_33281
    obo:IAO_0000115 "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "antimicrobial agent"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000148 .

obo:CHEBI_33696
    obo:IAO_0000115 "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid."^^xsd:string ;
    obo:IAO_0000118 "nucleic acids"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "nucleic acid"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_33839 .

obo:CHEBI_33697
    obo:IAO_0000115 "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins."^^xsd:string ;
    obo:IAO_0000118 "ribonucleic acid"^^xsd:string, "ribonucleic acids"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "ribonucleic acid"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_33839 .

obo:CHEBI_33839
    obo:IAO_0000115 "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass."^^xsd:string ;
    obo:IAO_0000118 "macromolecule"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "macromolecule"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_35341
    obo:IAO_0000115 "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene."^^xsd:string ;
    obo:IAO_0000118 "Steroid"^^xsd:string, "steroids"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "steroid"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_35482
    obo:IAO_0000115 "A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "opioid analgesic"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000148 .

obo:CHEBI_35717
    obo:IAO_0000115 "A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "sedative"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000148 .

obo:CHEBI_36333
    obo:IAO_0000115 "Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block."^^xsd:string ;
    obo:IAO_0000118 "local anaesthetic"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "local anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_38867 .

obo:CHEBI_38867
    obo:IAO_0000115 "Substance which produces loss of feeling or sensation."^^xsd:string ;
    obo:IAO_0000118 "anaesthetic"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000148 .

obo:CHEBI_38870
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "inhalation anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_38867 .

obo:CHEBI_38877
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "intravenous anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_38867 .

obo:CHEBI_42191
    obo:IAO_0000118 "(ethane-1,2-diyldinitrilo)tetraacetate"^^xsd:string, "(ethane-1,2-diyldinitrilo)tetraacetic acid"^^xsd:string, "Ethylenediaminetetraacetic acid"^^xsd:string, "ethylenediaminetetraacetic acid"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "ethylenediaminetetraacetic acid"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom obo:OBIB_0000022
    ] .

obo:CHEBI_44915
    obo:IAO_0000115 "A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group."^^xsd:string ;
    obo:IAO_0000118 "2,6-bis(propan-2-yl)phenol"^^xsd:string, "Propofol"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "propofol"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_4717
    obo:IAO_0000115 "An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon."^^xsd:string ;
    obo:IAO_0000118 "1-{1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydropyridin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "droperidol"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_4910
    obo:IAO_0000115 "The ethyl ester of 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylic acid. It is an intravenous general anaesthetic with no analgesic activity."^^xsd:string ;
    obo:IAO_0000118 "Etomidate"^^xsd:string, "ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "etomidate"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_49575
    obo:IAO_0000115 "A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5."^^xsd:string ;
    obo:IAO_0000118 "Diazepam"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "diazepam"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_50913
    obo:IAO_0000115 "Any compound used for the purpose of preserving biological tissues from decay in such a way as to allow for the preparation of thin, stained sections for subsequent histological study."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "fixative"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:CHEBI_50919
    obo:IAO_0000115 "A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "antiemetic"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000148 .

obo:CHEBI_51371
    obo:IAO_0000115 "A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "muscle relaxant"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000148 .

obo:CHEBI_52993
    obo:IAO_0000115 "A 1,4-benzodiazepinone compound having a methyl substituent at the 1-position, a hydroxy substituent at the 3-position, a 2-chlorophenyl group at the 5-position and a chloro substituent at the 7-position."^^xsd:string ;
    obo:IAO_0000118 "7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one"^^xsd:string, "Lormetazepam"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "lormetazepam"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_53258
    obo:IAO_0000115 "The trisodium salt of citric acid."^^xsd:string ;
    obo:IAO_0000118 "trisodium 2-hydroxypropane-1,2,3-tricarboxylate"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "sodium citrate"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom obo:OBIB_0000022
    ] .

obo:CHEBI_5790
    obo:IAO_0000115 "A  morphinane alkaloid that is a hydrogenated ketone derivative of morphine. A semi-synthetic drug, it is a centrally acting pain medication of the opioid class."^^xsd:string ;
    obo:IAO_0000118 "3-hydroxy-17-methyl-4,5alpha-epoxymorphinan-6-one"^^xsd:string, "Hydromorphone"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "hydromorphone"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_6015
    obo:IAO_0000118 "2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane"^^xsd:string, "Isoflurane"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "isoflurane"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_6121
    obo:IAO_0000115 "A member of the class of cyclohexanones in which one of the hydrogens at position 2 is substituted by a 2-chlorophenyl group, while the other is substituted by a methylamino group."^^xsd:string ;
    obo:IAO_0000118 "2-(2-chlorophenyl)-2-(methylamino)cyclohexanone"^^xsd:string, "KETAMINE"^^xsd:string, "Ketamine"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "ketamine"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_61219
    obo:IAO_0000115 "A chloride salt in which the negative charge of the chloride ions is balanced by succinylcholine dications."^^xsd:string ;
    obo:IAO_0000118 "2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) dichloride"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "succinylcholine chloride (anhydrous)"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_6456
    obo:IAO_0000115 "The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline."^^xsd:string ;
    obo:IAO_0000118 "Lidocaine"^^xsd:string, "N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "lidocaine"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_65265
    obo:IAO_0000115 "Any substance which is used to neutralise stomach acidity."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "antacid"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000148 .

obo:CHEBI_6754
    obo:IAO_0000115 "A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain."^^xsd:string ;
    obo:IAO_0000118 "ethyl 1-methyl-4-phenylpiperidine-4-carboxylate"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "pethidine"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_6834
    obo:IAO_0000115 "The sodium salt of methohexital."^^xsd:string ;
    obo:IAO_0000118 "sodium 5-(hex-3-yn-2-yl)-1-methyl-4,6-dioxo-5-(prop-2-en-1-yl)-1,4,5,6-tetrahydropyrimidin-2-olate"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "methohexital sodium"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_7773
    obo:IAO_0000118 "Ondansetron"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "Ondansetron"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_7907
    obo:IAO_0000115 "A steroid ester in which a 5alpha-androstane skeleton is C-3alpha- and C-17beta-disubstituted with acetoxy groups and 2beta- and 16beta-disubstituted with 1-methylpiperidinium-1-yl groups. It is a non-depolarizing curare-mimetic muscle relaxant."^^xsd:string ;
    obo:IAO_0000118 "3alpha,17beta-diacetoxy-2beta,16beta-bis(1-methylpiperidinium-1-yl)-5alpha-androstane"^^xsd:string, "Pancuronium"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "pancuronium"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_8430
    obo:IAO_0000115 "A benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol."^^xsd:string ;
    obo:IAO_0000118 "2-(diethylamino)ethyl 4-aminobenzoate"^^xsd:string, "Procaine"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "procaine"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_8776
    obo:IAO_0000115 "A member of the class of  furans used to treat  peptic ulcer disease (PUD) and gastroesophageal reflux disease."^^xsd:string ;
    obo:IAO_0000118 "(E)-N-{2-[({5-[(dimethylamino)methyl]-2-furyl}methyl)sulfanyl]ethyl}-N'-methyl-2-nitroethene-1,1-diamine"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "ranitidine"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_9561
    obo:IAO_0000115 "An organic sodium salt having thiopental(1-) as the counter-ion."^^xsd:string ;
    obo:IAO_0000118 "sodium 5-ethyl-4,6-dioxo-5-(pentan-2-yl)-1,4,5,6-tetrahydropyrimidine-2-thiolate"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "thiopental sodium"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CHEBI_9939
    obo:IAO_0000115 "A 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidino- and 16beta-N-methylpiperidinium substituents."^^xsd:string ;
    obo:IAO_0000118 "(2beta,3alpha,5alpha,16beta,17beta)-3,17-diacetoxy-16-(1-methylpiperidinium-1-yl)-2-(piperidin-1-yl)androstane"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/chebi.owl> ;
    a owl:Class ;
    rdfs:label "vecuronium"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:CLO_0000001
    obo:IAO_0000115 "A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture"@en, """A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture
"""^^xsd:string, "一个培养细胞，它是一个细胞株（一个稳定的，同质的细胞群，具有共同的生物学起源和增殖史）的一部分", """一个培养细胞，它是一个细胞株（一个稳定的，同质的细胞群，具有共同的生物学起源和增殖史）的一部分
"""^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/clo.owl> ;
    a owl:Class ;
    rdfs:label "cell line cell"^^xsd:string, "cell line cell"@en, "细胞系细胞"@zh ;
    rdfs:subClassOf obo:OBI_0001866 .

obo:CLO_0000019
    obo:IAO_0000115 "A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line.", "A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line."@en, "预期能够进行无限次分裂的细胞系细胞，作为永生细胞系一部分，能够支持体外无限增殖。" ;
    obo:IAO_0000118 "continuous cell line cell", "continuous cell line cell"@en, "permanent cell line cell", "permanent cell line cell"@en, "永久细胞系细胞", "连续细胞系细胞" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/clo.owl> ;
    a owl:Class ;
    rdfs:label "immortal cell line cell"^^xsd:string, "immortal cell line cell"@en, "永生细胞系细胞"@zh ;
    rdfs:subClassOf obo:CLO_0000001 .

obo:CLO_0000031
    obo:IAO_0000112 """He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.:  \"To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene\". 
	
Note that common usage in the literature is often of the form \"a human colorectal cancer cell line\", as seen above. But such references to studies in \"a line\" refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells.  It is these discrete populations that we refer to as 'cell lines'.
""", """He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.:  \"To evaluate the transcriptional effects of APC, we studied a human colorectal cancer cell line (HT29-APC) containing a zinc-inducible APC gene and a control cell line (HT29–β-Gal) containing an analogous inducible lacZ gene\". 

Note that common usage in the literature is often of the form \"a human colorectal cancer cell line\", as seen above. But such references to studies in \"a line\" refer to the fact that discrete populations of cells that are input into culturing or experiments, not an entire lineage of cells.  It is these discrete populations that we refer to as 'cell lines'.
"""^^xsd:string, """He, Tong-Chuan, et al., Identification of c-MYC as a target of the APC pathway. Science 281.5382 (1998): 1509-1512.:  \"为了评估APC的转录效应，我们研究了含有锌诱导型APC基因的人结直肠癌细胞系（HT29-APC）和含有类似诱导型lacZ基因的对照细胞系（HT29-β-Gal）\".  

请注意，文献中的常见用法通常是“人类结直肠癌细胞系”的形式\",如上所见。 但是对\"一个细胞系\"研究的这种引用，指的是输入培养或实验的离散细胞群体，而不是整个细胞系。 我们将这些离散的群体称为'细胞系'。
""" ;
    obo:IAO_0000115 "A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). "@en, """A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture).  
"""^^xsd:string, "一个培养细胞群体，其代表具有共同增殖历史（即已经在培养中一起连续传代）的遗传稳定且同质的培养细胞群体。"@zh, """培养的细胞群体代表具有共同繁殖历史（即已经在培养中一起连续传代）的遗传稳定且同质的培养细胞群体。 
""" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/clo.owl> ;
    a owl:Class ;
    rdfs:label "cell line"@en, "细胞系"@zh ;
    rdfs:subClassOf obo:OBI_0001905 .

obo:CLO_0009828
    obo:IAO_0000115 "A cell line that is expected to be capable of indefinite propagation in an vitro culture."^^xsd:string ;
    obo:IAO_0000118 "permanent cell line"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/clo.owl> ;
    a owl:Class ;
    rdfs:label "immortal cell line"@en ;
    rdfs:subClassOf obo:CLO_0000031 .

obo:CL_0000000
    obo:IAO_0000115 "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "cell"^^xsd:string, "cell"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:CL_0000001
    obo:IAO_0000115 "A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "primary cultured cell"^^xsd:string ;
    rdfs:subClassOf obo:CL_0000010 .

obo:CL_0000003
    obo:IAO_0000115 "A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment)."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "native cell"^^xsd:string ;
    rdfs:subClassOf obo:CL_0000000 .

obo:CL_0000010
    obo:IAO_0000115 "A cell in vitro that is or has been maintained or propagated as part of a cell culture."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "cultured cell"^^xsd:string ;
    rdfs:subClassOf obo:CL_0000578 .

obo:CL_0000232
    obo:IAO_0000115 "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "erythrocyte"^^xsd:string ;
    rdfs:subClassOf obo:CL_0000000 .

obo:CL_0000558
    obo:IAO_0000115 "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "reticulocyte"^^xsd:string ;
    rdfs:subClassOf obo:CL_0000000 .

obo:CL_0000578
    obo:IAO_0000115 "A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "experimentally modified cell in vitro"^^xsd:string ;
    rdfs:subClassOf obo:CL_0001034 .

obo:CL_0000738
    obo:IAO_0000115 "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "leukocyte"^^xsd:string ;
    rdfs:subClassOf obo:CL_0000000 .

obo:CL_0001034
    obo:IAO_0000115 "A cell that is maintained or propagated in a controlled artificial environment for use in an investigation."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    a owl:Class ;
    rdfs:label "cell in vitro"^^xsd:string ;
    rdfs:subClassOf obo:CL_0000000 .

obo:DOID_0050687
    obo:IAO_0000115 "A cancer that is classified by the type of cell from which it is derived."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "cell type cancer"^^xsd:string ;
    rdfs:subClassOf obo:DOID_162 .

obo:DOID_0050917
    obo:IAO_0000115 "A lung combined type small cell carcinoma that has_material_basis_in epithelial tissue of glandular origin."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "lung combined type small cell adenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_3905 .

obo:DOID_0050933
    obo:IAO_0000115 "An ovarian carcinoma that has_material_basis_in the lining of the ovary and produces a serum-like fluid."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovarian serous carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_0050934
    obo:IAO_0000115 "An ovarian carcinoma that has_material_basis_in cells with clear cytoplasm and glycogen secreting hob nail cells."^^xsd:string ;
    obo:IAO_0000118 "clear-cell ovarian carcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovarian clear cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_0080183
    obo:IAO_0000115 "A colon carcinoma that is characterized by a solid growth pattern."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "medullary colon carcinoma"@en ;
    rdfs:subClassOf obo:DOID_1520 .

obo:DOID_0080184
    obo:IAO_0000115 "A bronchiolo-alveolar adenocarcinoma that is characterized by a mixed array of different patterns (acinar, papillary, bronchioloalveolar, solid with mucin)."^^xsd:string ;
    obo:IAO_0000118 "indeterminate bronchioloalveolar carcinoma"@en, "mixed mucinous and non-mucinous bronchioloalveolar adenocarcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "mixed mucinous and nonmucinous bronchioloalveolar adenocarcinoma"@en ;
    rdfs:subClassOf obo:DOID_4926 .

obo:DOID_0080185
    obo:IAO_0000115 "A bronchiolo-alveolar adenocarcinoma that is characterized by a tumour cells containing abundant mucin in their cytoplasm and composed of tall columnar cells growing along alveolar walls without stromal invasion."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "mucinous bronchioloalveolar adenocarcinoma"@en ;
    rdfs:subClassOf obo:DOID_4926 .

obo:DOID_0080186
    obo:IAO_0000115 "A bronchiolo-alveolar adenocarcinoma that is characterized by cells with cuboidal or columnar morphology with eosinophilic or clear cytoplasm and shows Clara cell or type 2 pneumocyte differentiation."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "nonmucinous bronchioloalveolar adenocarcinoma"@en ;
    rdfs:subClassOf obo:DOID_4926 .

obo:DOID_1520
    obo:IAO_0000115 "A colon cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells."^^xsd:string ;
    obo:IAO_0000118 "Colonic carcinoma"@en, "carcinoma of colon"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "colon carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_162 .

obo:DOID_162
    obo:IAO_0000115 "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis."^^xsd:string ;
    obo:IAO_0000118 "malignant neoplasm"@en, "malignant tumor"@en, "primary cancer"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "cancer"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000031 .

obo:DOID_192
    obo:IAO_0000115 "A reproductive organ cancer that is located_in the sex cord-derived tissues of the ovary or testis and derives_from granulosa cells, Leydig cells, Sertoli cells, and fibroblasts."^^xsd:string ;
    obo:IAO_0000118 "Sex Cord-Stromal neoplasm"@en, "Sex cord stromal tumour"@en, "Specialized gonadal neoplasm"@en, "Specialized gonadal tumor"@en, "Specialized gonadal tumour"@en, "sex cord-gonadal stromal tumour"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "sex cord-gonadal stromal tumor"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_2152
    obo:IAO_0000115 "An ovarian cancer that is derives_from ovarian surface epithelium."^^xsd:string ;
    obo:IAO_0000118 "Ovarian Surface epithelial-Stromal tumor"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovary epithelial cancer"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_2155
    obo:IAO_0000118 "malignant Ovarian germ cell tumor"@en, "malignant germ cell tumor of ovary"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "malignant ovarian germ cell neoplasm"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_234
    obo:IAO_0000115 "A colon carcinoma that derives_from epithelial cells of glandular origin."^^xsd:string ;
    obo:IAO_0000118 "Colonic adenocarcinoma"@en, "adenocarcinoma of colon"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "colon adenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_1520 .

obo:DOID_2394
    obo:IAO_0000115 "A female reproductive organ cancer that is located_in the ovary."^^xsd:string ;
    obo:IAO_0000118 "malignant Ovarian tumor"@en, "malignant tumour of ovary"@en, "ovarian neoplasm"@en, "ovary neoplasm"@en, "primary ovarian cancer"@en, "tumor of the Ovary"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovarian cancer"^^xsd:string ;
    rdfs:subClassOf obo:DOID_162 .

obo:DOID_2999
    obo:IAO_0000115 "A sex cord-gonadal stromal tumor that has_material_basis_in granulosa cells and arises from the sex cord stroma."^^xsd:string ;
    obo:IAO_0000118 "Granulosa cell neoplasm"@en, "Granulosa cell tumor, adult type"@en, "Granulosa cell tumour, sarcomatoid"@en, "malignant granulosa cell neoplasm"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "granulosa cell tumor"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_3029
    obo:IAO_0000118 "Colonic mucinous adenocarcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "colon mucinous adenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_1520 .

obo:DOID_3033
    obo:IAO_0000118 "Colonic Signet Ring adenocarcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "colon signet ring adenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_1520 .

obo:DOID_3604
    obo:IAO_0000115 "An ovarian cystadenocarcinoma that is characterized by the presence of mucin."^^xsd:string ;
    obo:IAO_0000118 "Ovarian mucinous cystadenocarcinoma"@en, "mucinous cystadenocarcinoma of ovary"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovarian mucinous cystadenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_3905
    obo:IAO_0000115 "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis."^^xsd:string ;
    obo:IAO_0000118 "cancer of lung"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "lung carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_162 .

obo:DOID_3907
    obo:IAO_0000115 "A non-small cell lung carcinoma that has_material_basis_in the squamous cell."^^xsd:string ;
    obo:IAO_0000118 "Epidermoid cell carcinoma of the lung"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "lung squamous cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_3905 .

obo:DOID_3910
    obo:IAO_0000115 "A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin."^^xsd:string ;
    obo:IAO_0000118 "bronchogenic lung adenocarcinoma"@en, "nonsmall cell adenocarcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "lung adenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_3905 .

obo:DOID_4000
    obo:IAO_0000115 "An ovarian epithelial cancer that derives_from epithelial transitional cells."^^xsd:string ;
    obo:IAO_0000118 "malignant ovarian transitional cell neoplasm"@en, "ovarian transitional cell cancer"@en, "transitional cell carcinoma of Ovary"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovary transitional cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_4217
    obo:IAO_0000115 "A malignant ovarian surface epithelial-stromal neoplasm that has_material_basis_in the surface epithelium of the ovary."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "malignant ovarian Brenner tumor"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_4450
    obo:IAO_0000115 "A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney."^^xsd:string ;
    obo:IAO_0000118 "RCC"@en, "adenocarcinoma of kidney"@en, "hypernephroma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "renal cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_4451 .

obo:DOID_4451
    obo:IAO_0000115 "A kidney cancer that derives_from the lining of the proximal convoluted tubule (the very small tubes in the kidney that filter the blood and remove waste products)."^^xsd:string ;
    obo:IAO_0000118 "carcinoma of kidney"@en, "kidney carcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "renal carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_162 .

obo:DOID_4463
    obo:IAO_0000118 "cystadenocarcinoma of kidney"@en, "renal cystadenocarcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "multilocular clear cell renal cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_4451 .

obo:DOID_4464
    obo:IAO_0000115 "A renal cell carcinoma that begins in distal collecting ducts of the kidney with a tubulopapillary morphology and intracytoplasmic mucicarminophilic material."^^xsd:string ;
    obo:IAO_0000118 "carcinoma of renal Collecting duct"@en, "renal Medullary carcinoma"@en, "renal carcinoma, collecting duct type"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "collecting duct carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_4451 .

obo:DOID_4465
    obo:IAO_0000115 "A renal cell carcinoma that is characterized by the development of multiple, bilateral papillary renal tumors."^^xsd:string ;
    obo:IAO_0000118 "Chromophil carcinoma of kidney"@en, "Papillary renal cell carcinoma"@en, "papillary kidney carcinoma"@en, "sporadic papillary renal cell carcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "papillary renal cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_4451 .

obo:DOID_4467
    obo:IAO_0000115 "A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope."^^xsd:string ;
    obo:IAO_0000118 "Clear cell carcinoma of kidney"@en, "clear cell kidney carcinoma"@en, "conventional (Clear cell) renal cell carcinoma"@en, "conventional renal cell carcinoma"@en, "renal clear cell carcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "clear cell renal cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_4451 .

obo:DOID_4471
    obo:IAO_0000115 "A renal cell carcinoma that has_material_basis_in chromophobe cell that appear pale when viewed under microscope, but that are larger and display different features than clear cells."^^xsd:string ;
    obo:IAO_0000118 "Chromophobe carcinoma of kidney"@en, "chromophobe adenocarcinoma"@en, "kidney chromophobe"@en, "renal cell carcinoma, chromophobe cell"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "chromophobe renal cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_4451 .

obo:DOID_4472
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "mucinous tubular and spindle renal cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_4451 .

obo:DOID_4926
    obo:IAO_0000115 "A lung adenocarcinoma characterized by a predominantly lepidic pattern and 5 mm or less invasion in greatest dimension."^^xsd:string ;
    obo:IAO_0000118 "Bronchioalveolar lung carcinoma"@en, "Bronchioloalveolar carcinoma"@en, "Minimally Invasive Lung Adenocarcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "bronchiolo-alveolar adenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_3910 .

obo:DOID_5519
    obo:IAO_0000115 "A squamous cell carcinoma that is located_in the colon."^^xsd:string ;
    obo:IAO_0000118 "Colonic Epidermoid carcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "colon squamous cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_1520 .

obo:DOID_5531
    obo:IAO_0000115 "An ovarian carcinoma that derives_from squamous epithelial cells."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovarian squamous cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_5588
    obo:IAO_0000115 "A papillary adenocarcinoma that is located_in the lung."^^xsd:string ;
    obo:IAO_0000118 "Papillary adenocarcinoma of the lung"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "lung papillary adenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_3910 .

obo:DOID_5629
    obo:IAO_0000115 "A colon carcinoma that derives_from squamous cells and gland-like cells."^^xsd:string ;
    obo:IAO_0000118 "Colonic Adenosquamous carcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "adenosquamous colon carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_1520 .

obo:DOID_5746
    obo:IAO_0000115 "An ovary serous adenocarcinoma that has_material_basis_in glandular epithelium, in which cystic accumulations of retained secretions are formed."^^xsd:string ;
    obo:IAO_0000118 "serous cystadenoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovarian serous cystadenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_5828
    obo:IAO_0000115 "An ovary adenocarcinoma that has_material_basis_in endometrial tissue."^^xsd:string ;
    obo:IAO_0000118 "Ovarian endometrioid carcinoma"@en, "endometrioid carcinoma ovary"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "endometrioid ovary carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_6067
    obo:IAO_0000115 "An ovary epithelial cancer that is characterized by the presence of mucin."^^xsd:string ;
    obo:IAO_0000118 "Ovarian mucinous tumor"@en, "malignant ovarian mucinous neoplasm"@en, "mucinous tumor of Ovary"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovarian mucinous neoplasm"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_6170
    obo:IAO_0000115 "A malignant ovarian surface epithelial-stromal neoplasm that is a mixed cell type cancer that has_material_basis_in carcinomatous (epithelial tissue) and sarcomatous (connective tissue) components."^^xsd:string ;
    obo:IAO_0000118 "Ovarian MMMT"@en, "ovarian malignant mesodermal (mullerian) mixed tumor"@en, "ovarian malignant mixed Mullerian tumor"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "ovarian carcinosarcoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_2394 .

obo:DOID_6482
    obo:IAO_0000118 "acinar adenocarcinoma of the lung"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "lung acinar adenocarcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_3910 .

obo:DOID_6727
    obo:IAO_0000118 "Colonic small cell carcinoma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "colon small cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_1520 .

obo:DOID_7045
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "basaloid lung carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_3905 .

obo:DOID_7267
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "lung clear cell carcinoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_3910 .

obo:DOID_769
    obo:IAO_0000115 "An autonomic nervous system neoplasm that derives_from immature nerve cells."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/doid.owl> ;
    a owl:Class ;
    rdfs:label "neuroblastoma"^^xsd:string ;
    rdfs:subClassOf obo:DOID_162 .

obo:DRON_00015464
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/dron.owl> ;
    a owl:Class ;
    rdfs:label "Paraffin"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:DRON_00017834
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/dron.owl> ;
    a owl:Class ;
    rdfs:label "Midazolam"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:ENVO_00010483
    obo:IAO_0000115 "A portion of environmental material is a fiat object part which forms the medium or part of the medium of an environmental system."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/envo.owl> ;
    a owl:Class ;
    rdfs:label "environmental material"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:ERO_0000905
    obo:IAO_0000115 "Biomolecule synthesis of RNA in vitro used for applications such as can be used in blot hybridizations and nuclease protection assays."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "in vitro transcription"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000094 .

obo:ERO_0000979
    obo:IAO_0000112 "Storage of perishable items in a freezer."^^xsd:string ;
    obo:IAO_0000115 "An instrument that consists of a thermally insulated compartment, cabinet, or room in which a subfreezing temperature is maintained for the rapid freezing and storing of perishable items."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "freezer"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000967, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:OBIB_0000010
    ], [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:OBIB_0000015
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000370
    ] .

obo:ERO_0001092
    obo:IAO_0000112 "A blood pressure monitor is a medical device."^^xsd:string ;
    obo:IAO_0000115 "An instrument used in the diagnosis of disease or other conditions or for use in the care, treatment, or prevention of disease that does not achieve any of its primary intended purposes by chemical action or by being metabolized."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "medical device "^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000968 .

obo:ERO_0001978
    obo:IAO_0000115 """A Jewish ethnic group comprised of persons who are descendants of Jews from Germany, Poland, Austria and Eastern Europe.
"""^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "Ashkenazi Jew"@en ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:ERO_0001979
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "Sephardic Jew"@en ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:ERO_0001983
    obo:IAO_0000115 "An ethnic group comprised of persons with African ancestral origins who self identify, or are identified, as African."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "African"@en ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:ERO_0002032
    obo:IAO_0000115 "An ethnic group that includes persons with significant ethnic contributions from more than one group."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "mixed ethnicity" ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:ERO_0002033
    obo:IAO_0000115 "A relationship between persons related as members of a domestic group, or a number of domestic groups linked through descent from a common ancestor, marriage, or adoption"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "family relationship"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000020 .

obo:ERO_0002037
    obo:IAO_0000115 "A family relationship between persons linked through descent from a common ancestor."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "biological family relationship"^^xsd:string ;
    rdfs:subClassOf obo:ERO_0002033 .

obo:ERO_0002047
    obo:IAO_0000115 "A lineal family relationship from a person to their biological parent."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "child relationship"^^xsd:string ;
    rdfs:subClassOf obo:ERO_0002037 .

obo:ERO_0002063
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "relationship by marriage"^^xsd:string ;
    rdfs:subClassOf obo:ERO_0002033 .

obo:ERO_0002076
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "Nordic, Icelandic" ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:ERO_0002087
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "Latino, Carribean"^^xsd:string ;
    rdfs:subClassOf obo:HANCESTRO_0014 .

obo:ERO_0002090
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "Latino, South American" ;
    rdfs:subClassOf obo:HANCESTRO_0014 .

obo:FLU_0001019
    obo:IAO_0000115 "A specimen barcode is a specimen identification number formatted as an optical machine-readable representation."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/flu.owl> ;
    a owl:Class ;
    rdfs:label "specimen barcode"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000721 .

obo:FMA_15584
    obo:IAO_0000118 "Left renal cortex"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Cortex of left kidney"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:FMA_17181
    obo:IAO_0000118 "Wall of distal ileum"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Wall of distal part of ileum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:FMA_19972
    obo:IAO_0000118 "Paries anterior (vagina)"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Anterior wall of vagina"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:FMA_19973
    obo:IAO_0000118 "Paries posterior (vagina)"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Posterior wall of vagina"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:FMA_22109
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Right tibial nerve"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0001323 .

obo:FMA_22110
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Left tibial nerve"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0001323 .

obo:FMA_242207
    obo:IAO_0000118 "Right frontal lobe cortex"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Cortex of right frontal lobe"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:FMA_24980
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Right leg"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:FMA_24981
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Left leg"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:FMA_37829
    obo:IAO_0000118 "Right leg skin"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Skin of right leg"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002097 .

obo:FMA_37830
    obo:IAO_0000118 "Left leg skin"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Skin of left leg"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002097 .

obo:FMA_43899
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Left posterior tibial artery"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0007610 .

obo:FMA_50707
    obo:IAO_0000115 "Spatial association relationship which describes the containment, adjacency and anatomical coordinates of physical anatomical entities. Examples: anatomical containment, anatomical adjacency, anatomical coordinate."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Anatomical location"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000141 .

obo:FMA_57987
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Right mammary gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:FMA_63008
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Mucosa of abdominal part of esophagus"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002469 .

obo:FMA_63062
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Muscularis mucosae of abdominal part of esophagus"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0004648 .

obo:FMA_83876
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/fma.owl> ;
    a owl:Class ;
    rdfs:label "Right hemisphere of cerebellum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:GAZ_00000448
    obo:IAO_0000115 "A reference to a place on the Earth, by its name or by its geographical location."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/gaz.owl> ;
    a owl:Class ;
    rdfs:label "geographic location"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:GEO_000000004
    obo:IAO_0000115 "a governmental organization that has a local, regional, or territorial government that recognizes a sovereign state as its higher political authority"@en ;
    obo:IAO_0000117 "Amanda Hicks"@en, "William R. Hogan"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/geo.owl> ;
    a owl:Class ;
    rdfs:label "subnational entity"@en ;
    rdfs:subClassOf obo:GEO_000000400 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:GEO_000000400
            [
                a owl:Restriction ;
                owl:onProperty obo:GEO_000000329 ;
                owl:someValuesFrom obo:GEO_000000396
            ]
        )
    ] .

obo:GEO_000000006
    obo:IAO_0000115 "A subnational entity that does not possess full political independence or sovereignty as a sovereign state, but remains politically outside of the controlling state and controls a geographical region that is outside the controlling state's integral region."@en ;
    obo:IAO_0000117 "Amanda Hicks"@en, "William R. Hogan"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/geo.owl> ;
    a owl:Class ;
    rdfs:comment "Typically, the common feature is that the dependency does not conduct foreign affairs, and relegates this authority to the sovereign state.  But otherwise, it is largely or completely autonomous relative to the administrative subdivisions.  Examples include Puerto Rico (U.S.), Guam (U.S.), Greenland (Denmark), French Polynesia (France), and Falkland Islands (United Kingdom). "@en ;
    rdfs:label "geopolitical dependency"@en ;
    rdfs:subClassOf obo:GEO_000000004 .

obo:GEO_000000329
    obo:IAO_0000115 "A governing organization G1 is subordinate to another governing organization G2 iff there is some authority possessed by G2 that is not possessed by G1 and G1's jurisdiction falls within the relevant jurisdiction of G2."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/geo.owl> ;
    a owl:ObjectProperty ;
    rdfs:comment """'is subordinate authority of'
Domain: governing organization
Range: governing organization
Formal properties: transitive, anti-symmetric, irreflexive
Natural language definition: A governing organization G1 is subordinate to another governing organization G2 iff there is some authority possessed by G2 that is not possessed by G1 and G1 falls within the relevant jurisdiction of G2.""" ;
    rdfs:label "is subordinate authority of"@en .

obo:GEO_000000370
    obo:IAO_0000111 "geographical entity of astronomical body"@en ;
    obo:IAO_0000115 "A material entity that is (1) a bona fide or fiat object part of the crust, any bodies of liquid on or contained within the crust, or planetary boundary layer (if present) of a terrestrial planet (including Earth), dwarf planet, exoplanet, natural satellite, planetesimal, or small Solar System body, and that (2) overlaps the planetary surface (including having a boundary that coincides with part of the planetary surface)."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en, "Matt Diller"@en, "William R. Hogan"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/geo.owl> ;
    a owl:Class ;
    rdfs:comment """Includes atmosphere, crust, geographical regions (e.g., the geographical region over which the state of Florida has jurisdiction), bodies of water, mountains, etc.

Generally, an individual organism is a distinct object that is not a part of the Earth, although this requires more thought.  But the intent is definitely for this class to NOT subsume organism universally.  Human beings are contained within, but not part of, the Earth, for example."""@en, "Note that despite the word 'planetary' in 'planetary surface', it refers generally to surface of dwarf planets, asteroids, moons, etc."@en, "We note that not all planets have a surface per se (e.g., gas giants such as Jupiter and Saturn).  So only planets, natural satellites, etc. with a planetary surface (with or without a planetary boundary layer) have geographical entities."@en, """We note that the term 'geography' is also applied to the Earth's moon, Mars, Venus, and possibly even other moons and planets in our own solar system and beyond.  

Thus, we are attempting to define things generally enough that they could be reused for the geographical entities/features on the Moon, Mars, other planets, exoplanets, other natural satellites (a.k.a moons), asteroids, etc."""@en ;
    rdfs:label "geographical entity"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:GEO_000000372
    obo:IAO_0000115 "A geographical entity that is demarcated at least in part by one or more closed fiat boundaries all of whose lines are part of the planetary surface."@en ;
    obo:IAO_0000117 "François Modave"@en, "Mathias Brochhausen"@en, "Matt Diller"@en, "William R. Hogan"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/geo.owl> ;
    a owl:Class ;
    rdfs:label "geographical region"@en ;
    rdfs:subClassOf obo:GEO_000000370 .

obo:GEO_000000396
    obo:IAO_0000115 "A governmental organization with a defined territory on which it exercises internal and external sovereignty, a permanent population, a government, and the capacity to enter into relations with other sovereign states."@en ;
    obo:IAO_0000117 "William R. Hogan"@en ;
    obo:IAO_0000118 "de facto sovereign state"@en, "de facto state"@en, "nation"@en, "nation state"@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Sovereign_state"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/geo.owl> ;
    a owl:Class ;
    rdfs:comment "Per Wikipedia, the word 'nation' does not always refer to soverign states.  For example, the \"nation of Islam\"."@en ;
    rdfs:label "sovereign state"@en ;
    rdfs:subClassOf obo:GEO_000000400 .

obo:GEO_000000400
    obo:IAO_0000115 """An organization that governs the people living in a particular geographical region or aggregate of geographical regions.  The geographical region it governs can change over time (such as the westward expansion of the United States and the addition of Hawaii). 

Note: this definition was taken over from \"geopolitical organization\"."""@en ;
    obo:IAO_0000117 "Amanda Hicks"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/geo.owl> ;
    a owl:Class ;
    rdfs:comment "IMPORTANT: The label \"geopolitical organization\" was previously used for OMRSE_00000044 (governmental organization).  \"geopoli organization\" is a label for a new and different class."@en ;
    rdfs:label "governmental organization"@en ;
    rdfs:subClassOf obo:OBI_0000245 .

obo:GO_0006955
    obo:IAO_0000115 "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/go.owl> ;
    a owl:Class ;
    rdfs:label "immune response" ;
    rdfs:subClassOf obo:GO_0008150 .

obo:GO_0008150
    obo:IAO_0000115 "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/go.owl> ;
    a owl:Class ;
    rdfs:label "biological_process" ;
    rdfs:subClassOf obo:BFO_0000015 .

obo:GO_0019814
    obo:IAO_0000115 "A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/go.owl> ;
    a owl:Class ;
    rdfs:label "immunoglobulin complex" ;
    rdfs:subClassOf obo:GO_0032991 .

obo:GO_0032991
    obo:IAO_0000115 "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/go.owl> ;
    a owl:Class ;
    rdfs:label "protein-containing complex" ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:HANCESTRO_0004
    obo:IAO_0000115 "Population category defined using ancestry informative markers (AIMs) based on genetic/genomic data" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "ancestry category" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:HANCESTRO_0008
    obo:IAO_0000115 "Includes individuals that either self-report or have been described as Asian but there was not sufficient information to allow classification as East Asian, Central Asian, South Asian or South-East Asian."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "Asian" ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:HANCESTRO_0014
    obo:IAO_0000115 """Includes individuals who either self-report or are described by authors as Hispanic, Latino, Latin American or one of the sub-populations
from this region. This category includes individuals with known admixture of primarily European, African and Native American ancestries, though some may have also a degree of Asian (e.g. Peru). We also note that the levels of admixture vary depending on the country, with Caribbean countries carrying higher levels of African admixture when compared to South American countries, for example. This category also includes individuals who genetically cluster with reference populations from this region, for example 1000 Genomes and/or HapMap CLM, MXL, PEL and PUR populations""" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "Hispanic or Latin American" ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:HANCESTRO_0019
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "Japanese" ;
    rdfs:subClassOf obo:HANCESTRO_0008 .

obo:HANCESTRO_0021
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "Chinese" ;
    rdfs:subClassOf obo:HANCESTRO_0008 .

obo:HANCESTRO_0463
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "American"@en ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:HANCESTRO_0487
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "Indian"@en ;
    rdfs:subClassOf obo:HANCESTRO_0008 .

obo:HANCESTRO_0568
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "African American" ;
    rdfs:subClassOf obo:HANCESTRO_0463 .

obo:HANCESTRO_0590
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/hancestro.owl> ;
    a owl:Class ;
    rdfs:label "European American" ;
    rdfs:subClassOf obo:HANCESTRO_0463 .

obo:IAO_0000001
    obo:IAO_0000111 "conditional specification"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A directive information entity that specifies what should happen if the trigger condition is fulfilled."@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000119 "OBI branch derived"@en, "OBI_0000349"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "conditional specification"@en ;
    rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000002
    obo:IAO_0000111 "example to be eventually removed"@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "example to be eventually removed"@en .

obo:IAO_0000003
    obo:IAO_0000111 "measurement unit label"@en ;
    obo:IAO_0000112 "Examples of measurement unit labels are liters, inches, weight per volume."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ;
    obo:IAO_0000116 """2009-03-16: provenance: a term measurement unit was
proposed for OBI (OBI_0000176) , edited by Chris Stoeckert and
Cristian Cocos, and subsequently moved to IAO where the objective for
which the original term was defined was satisfied with the definition
of this, different, term."""@en, "2009-03-16: review of this term done during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "measurement unit label"@en ;
    rdfs:subClassOf obo:IAO_0000009 .

obo:IAO_0000004
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:DatatypeProperty ;
    rdfs:label "has measurement value"@en .

obo:IAO_0000005
    obo:IAO_0000111 "objective specification"@en ;
    obo:IAO_0000112 "In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ;
    obo:IAO_0000116 "2009-03-16: original definition when imported from OBI read: \"objective is an non realizable information entity which can serve as that  proper part of a plan towards which the realization of the plan is directed.\""@en, "2014-03-31: In the example of usage (\"In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction\") there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that."@en, "Answers the question, why did you do this experiment?"@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Barry Smith"@en, "PERSON: Bjoern Peters"@en, "PERSON: Jennifer Fostel"@en ;
    obo:IAO_0000118 "goal specification"@en ;
    obo:IAO_0000119 "OBI Plan and Planned Process/Roles Branch"@en, "OBI_0000217"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "objective specification"@en ;
    rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000007
    obo:IAO_0000112 "Pour the contents of flask 1 into flask 2"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A directive information entity that describes an action the bearer will take."@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000119 "OBI Plan and Planned Process branch"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "action specification"@en ;
    rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000009
    obo:IAO_0000111 "datum label"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ;
    obo:IAO_0000116 "http://www.golovchenko.org/cgi-bin/wnsearch?q=label#4n"@en ;
    obo:IAO_0000117 "GROUP: IAO"@en ;
    obo:IAO_0000232 """9/22/11 BP: changed the rdfs:label for this class from 'label' to 'datum label' to convey that this class is not intended to cover all kinds of labels (stickers, radiolabels, etc.), and not even all kind of textual labels, but rather the kind of labels occuring in a datum. 
""" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "datum label"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000027
    obo:IAO_0000111 "data item"@en ;
    obo:IAO_0000112 "Data items include counts of things, analyte concentrations, and statistical summaries."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ;
    obo:IAO_0000116 "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers."@en, "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum."@en, "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym."@en, "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/", """JAR: datum     -- well, this will be very tricky to define, but maybe some 
information-like stuff that might be put into a computer and that is 
meant, by someone, to denote and/or to be interpreted by some 
process... I would include lists, tables, sentences... I think I might 
defer to Barry, or to Brian Cantwell Smith

JAR: A data item is an approximately justified approximately true approximate belief"""@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Chris Stoeckert"@en, "PERSON: Jonathan Rees"@en ;
    obo:IAO_0000118 "data"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "data item"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000028
    obo:IAO_0000111 "symbol"@en ;
    obo:IAO_0000112 "a serial number such as \"12324X\""@en, "a stop sign"@en, "a written proper name such as \"OBI\""@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity."@en ;
    obo:IAO_0000116 "20091104, MC: this needs work and will most probably change"@en, "2014-03-31: We would like to have a deeper analysis of 'mark' and 'sign' in the future (see https://github.com/information-artifact-ontology/IAO/issues/154)."@en ;
    obo:IAO_0000117 "PERSON: James A. Overton"@en, "PERSON: Jonathan Rees"@en ;
    obo:IAO_0000119 "based on Oxford English Dictionary"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "symbol"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000029
    obo:IAO_0000111 "numeral"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A symbol that denotes a number."@en ;
    obo:IAO_0000117 "PERSON: Jonathan Rees"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "numeral"@en ;
    rdfs:subClassOf obo:IAO_0000028 .

obo:IAO_0000030
    obo:IAO_0000111 "information content entity"@en ;
    obo:IAO_0000112 "Examples of information content entites include journal articles, data, graphical layouts, and graphs."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A generically dependent continuant that is about some thing."@en ;
    obo:IAO_0000116 "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)."@en, """information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907).

Previous. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity."""@en ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"@en ;
    obo:IAO_0000119 "OBI_0000142"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "information content entity"@en ;
    rdfs:subClassOf obo:BFO_0000031 .

obo:IAO_0000032
    obo:IAO_0000112 "10 feet. 3 ml."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ;
    obo:IAO_0000116 """2009-03-16: we decided to keep datum singular in scalar measurement datum, as in
this case we explicitly refer to the singular form"""@en, "Would write this as: has_part some 'measurement unit label' and has_part some numeral and has_part exactly 2, except for the fact that this won't let us take advantage of OWL reasoning over the numbers. Instead use has measurment value property to represent the same. Use has measurement unit label (subproperty of has_part) so we can easily say that there is only one of them."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "scalar measurement datum"@en ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:IAO_0000033
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ;
    obo:IAO_0000116 "2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was  \"is the specification of a process that can be concretized and realized by an actor\" with alternative term  \"instruction\".It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term."@en, "2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it."@en, "8/6/2009 Alan Ruttenberg: Changed label from \"information entity about a realizable\" after discussions at ICBO"@en, "Werner pushed back on calling it realizable information entity as it isn't realizable. However this name isn't right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn't about the plan, it, once concretized, *is* the plan. -Alan"@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bjoern Peters"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "directive information entity"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000039
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has measurement unit label"@en ;
    rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000064
    obo:IAO_0000111 "algorithm"@en ;
    obo:IAO_0000112 "PMID: 18378114.Genomics. 2008 Mar 28. LINKGEN: A new algorithm to process data in genetic linkage studies."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ;
    obo:IAO_0000117 "Philippe Rocca-Serra"@en, "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000119 "OBI_0000270"@en, "adapted from discussion on OBI list (Matthew Pocock, Christian Cocos, Alan Ruttenberg)"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "algorithm"@en ;
    rdfs:subClassOf obo:IAO_0000104 .

obo:IAO_0000078
    obo:IAO_0000111 "curation status specification"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
    obo:IAO_0000116 "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)"@en ;
    obo:IAO_0000117 "PERSON:Bill Bug"@en ;
    obo:IAO_0000119 "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en, "OBI_0000266"@en ;
    a owl:Class ;
    rdfs:label "curation status specification"@en ;
    rdfs:subClassOf obo:IAO_0000102 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:oneOf (obo:IAO_0000002
            obo:IAO_0000120
            obo:IAO_0000121
            obo:IAO_0000122
            obo:IAO_0000123
            obo:IAO_0000124
            obo:IAO_0000125
            obo:IAO_0000423
            obo:IAO_0000428
        )
    ] .

obo:IAO_0000100
    obo:IAO_0000111 "data set"@en ;
    obo:IAO_0000112 "Intensity values in a CEL file or from multiple CEL files comprise a data set (as opposed to the CEL files themselves)."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ;
    obo:IAO_0000116 "2009/10/23 Alan Ruttenberg. The intention is that this term represent collections of like data. So this isn't for, e.g. the whole contents of a cel file, which includes parameters, metadata etc. This is more like java arrays of a certain rather specific type"@en, "2014-05-05: Data sets are aggregates and thus must include two or more data items. We have chosen not to add logical axioms to make this restriction." ;
    obo:IAO_0000117 "person:Allyson Lister"@en, "person:Chris Stoeckert"@en ;
    obo:IAO_0000119 "OBI_0000042"@en, "group:OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "data set"@en ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000101
    obo:IAO_0000111 "image"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface."@en ;
    obo:IAO_0000117 "person:Alan Ruttenberg"@en, "person:Allyson"@en, "person:Chris Stoeckert"@en ;
    obo:IAO_0000119 "OBI_0000030"@en, "group:OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "image"@en ;
    rdfs:subClassOf obo:IAO_0000308 .

obo:IAO_0000102
    obo:IAO_0000111 "data about an ontology part"@en ;
    obo:IAO_0000115 "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "data about an ontology part"@en ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000103
    obo:IAO_0000111 "failed exploratory term"@en ;
    obo:IAO_0000115 "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    a obo:IAO_0000225, owl:NamedIndividual ;
    rdfs:label "failed exploratory term"@en .

obo:IAO_0000104
    obo:IAO_0000111 "plan specification"@en ;
    obo:IAO_0000112 "PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ;
    obo:IAO_0000116 "2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was \" a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan\". It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term."@en, "2014-03-31: A plan specification can have other parts, such as conditional specifications."@en, "Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved"@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000119 "OBI Plan and Planned Process branch"@en, "OBI_0000344"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:comment """2/3/2009 Comment from OBI review.

Action specification not well enough specified.
Conditional specification not well enough specified.
Question whether all plan specifications have objective specifications.

Request that IAO either clarify these or change definitions not to use them"""@en ;
    rdfs:label "plan specification"@en ;
    rdfs:subClassOf obo:IAO_0000033 .

obo:IAO_0000109
    obo:IAO_0000111 "measurement datum"@en ;
    obo:IAO_0000112 "Examples of measurement data are the recoding of the weight of a mouse as {40,mass,\"grams\"}, the recording of an observation of the behavior of the mouse {,process,\"agitated\"}, the recording of the expression level of a gene as measured through the process of microarray experiment {3.4,luminosity,}."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ;
    obo:IAO_0000116 "2/2/2009 is_specified_output of some assay?"@en ;
    obo:IAO_0000117 "person:Chris Stoeckert"@en ;
    obo:IAO_0000119 "OBI_0000305"@en, "group:OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "measurement datum"@en ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000111
    obo:IAO_0000111 "editor preferred term"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ;
    obo:IAO_0000117 "PERSON:Daniel Schober"@en ;
    obo:IAO_0000119 "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "editor preferred term"@en .

obo:IAO_0000112
    obo:IAO_0000111 "example of usage"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en ;
    obo:IAO_0000117 "PERSON:Daniel Schober"@en ;
    obo:IAO_0000119 "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "example of usage"@en .

obo:IAO_0000113
    obo:IAO_0000111 "in branch"@en ;
    obo:IAO_0000115 "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ;
    obo:IAO_0000117 "GROUP:OBI"@en ;
    obo:IAO_0000119 "OBI_0000277"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "in branch"@en .

obo:IAO_0000114
    obo:IAO_0000111 "has curation status"@en ;
    obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Bill Bug"@en, "PERSON:Melanie Courtot"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "has curation status"@en .

obo:IAO_0000115
    obo:IAO_0000111 "definition"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ;
    obo:IAO_0000116 """2012-04-05: 
Barry Smith

The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions'  is terrible.

Can you fix to something like:

A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property.

Alan Ruttenberg

Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. 

On the specifics of the proposed definition:

We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. 

Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. 

We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.  """@en ;
    obo:IAO_0000117 "PERSON:Daniel Schober"@en ;
    obo:IAO_0000119 "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "definition"@en .

obo:IAO_0000116
    obo:IAO_0000111 "editor note"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ;
    obo:IAO_0000117 "PERSON:Daniel Schober"@en ;
    obo:IAO_0000119 "GROUP:OBI:<http://purl.obofoundry.org/obo/obi>"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "editor note"@en .

obo:IAO_0000117
    obo:IAO_0000111 "term editor"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ;
    obo:IAO_0000116 "20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115."@en ;
    obo:IAO_0000117 "PERSON:Daniel Schober"@en ;
    obo:IAO_0000119 "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "term editor"@en .

obo:IAO_0000118
    obo:IAO_0000111 "alternative term"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "An alternative name for a class or property which means the same thing as the preferred name (semantically equivalent)"@en ;
    obo:IAO_0000117 "PERSON:Daniel Schober"@en ;
    obo:IAO_0000119 "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "alternative term"@en .

obo:IAO_0000119
    obo:IAO_0000111 "definition source"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ;
    obo:IAO_0000117 "PERSON:Daniel Schober"@en ;
    obo:IAO_0000119 "Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w"@en, "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "definition source"@en .

obo:IAO_0000120
    obo:IAO_0000111 "metadata complete"@en ;
    obo:IAO_0000115 "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "metadata complete"@en .

obo:IAO_0000121
    obo:IAO_0000111 "organizational term"@en ;
    obo:IAO_0000115 "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "organizational term"@en .

obo:IAO_0000122
    obo:IAO_0000111 "ready for release"@en ;
    obo:IAO_0000115 "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release.  Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "ready for release"@en .

obo:IAO_0000123
    obo:IAO_0000111 "metadata incomplete"@en ;
    obo:IAO_0000115 "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "metadata incomplete"@en .

obo:IAO_0000124
    obo:IAO_0000111 "uncurated"@en ;
    obo:IAO_0000115 "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "uncurated"@en .

obo:IAO_0000125
    obo:IAO_0000111 "pending final vetting"@en ;
    obo:IAO_0000115 "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "pending final vetting"@en .

obo:IAO_0000129
    obo:IAO_0000111 "version number"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A version number is an information content entity which is a sequence of characters borne by part of each of a class of manufactured products or its packaging and indicates its order within a set of other products having the same name."@en ;
    obo:IAO_0000116 "Note: we feel that at the moment we are happy with a general version number, and that we will subclass as needed in the future. For example, see 7. genome sequence version"@en ;
    obo:IAO_0000117 "GROUP: IAO"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "version number"@en ;
    rdfs:subClassOf obo:IAO_0000028 .

obo:IAO_0000132
    obo:IAO_0000111 "lot number"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A lot number is an information content entity which is an identical sequence of character borne by part of manufactured product or its packaging for each instances of a product class in a discrete batch of an item. Lot numbers are usually assigned to each separate production run of an item. Manufacturing as a lot might be due to a variety of reasons, for example,  a single process during which many individuals are made from the same portion of source material. Lot numbers can be encoded in a pattern  of other information objects, such as bar codes, numerals, or patterns of dots."@en ;
    obo:IAO_0000117 "GROUP: IAO"@en ;
    obo:IAO_0000118 "batch number"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "lot number"@en ;
    rdfs:subClassOf obo:IAO_0000028 .

obo:IAO_0000136
    obo:IAO_0000112 "This document is about information artifacts and their representations"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A (currently) primitive relation that relates an information artifact to an entity."@en ;
    obo:IAO_0000116 """7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of \"mentions\" relation. Weaken the is_about relationship to be primitive. 

We will try to build it back up by elaborating the various subproperties that are more precisely defined.

Some currently missing phenomena that should be considered \"about\" are predications - \"The only person who knows the answer is sitting beside me\" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic."""@en ;
    obo:IAO_0000117 "person:Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Smith, Ceusters, Ruttenberg, 2000 years of philosophy"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "is about"@en .

obo:IAO_0000140
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A settings datum is a datum that denotes some configuration of an instrument."@en ;
    obo:IAO_0000116 """2/3/2009 Feedback from OBI

This should be a \"setting specification\". There is a question of whether it is information about a realizable or not.

Pro other specification are about realizables.
Cons sometimes specifies a quality which is not a realizable."""@en, "Alan grouped these in placeholder for the moment. Name by analogy to measurement datum."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "setting datum"@en ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:IAO_0000144
    obo:IAO_0000111 "conclusion textual entity"@en ;
    obo:IAO_0000112 "that fucoidan has a small statistically significant effect on AT3 level but no useful clinical effect as in-vivo anticoagulant, a paraphrase of part of the last paragraph of the discussion section of the paper 'Pilot clinical study to evaluate the anticoagulant activity of fucoidan', by Lowenthal et. al.PMID:19696660"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers."@en ;
    obo:IAO_0000116 "2009/09/28 Alan Ruttenberg. Fucoidan-use-case"@en, "2009/10/23 Alan Ruttenberg: We need to work on the definition still"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "conclusion textual entity"@en ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000178
    obo:IAO_0000111 "material information bearer"@en ;
    obo:IAO_0000112 "A page of a paperback novel with writing on it. The paper itself is a material information bearer, the pattern of ink is the information carrier."@en, "a brain"@en, "a hard drive"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A material entity in which a concretization of an information content entity inheres."@en ;
    obo:IAO_0000117 "GROUP: IAO"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "material information bearer"@en ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000053 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000059 ;
                    owl:someValuesFrom obo:IAO_0000030
                ]
            ]
        )
    ] .

obo:IAO_0000219
    obo:IAO_0000112 "A person's name denotes the person. A variable name in a computer program denotes some piece of memory. Lexically equivalent strings can denote different things, for instance \"Alan\" can denote different people. In each case of use, there is a case of the denotation relation obtaining, between \"Alan\" and the person that is being named."@en ;
    obo:IAO_0000115 "A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically"@en ;
    obo:IAO_0000116 """2009-11-10 Alan Ruttenberg. Old definition said the following to emphasize the generic nature of this relation. We no longer have 'specifically denotes', which would have been primitive, so make this relation primitive.
g denotes r =def 
r is a portion of reality
there is some c that is a concretization of g 
every c that is a concretization of g specifically denotes r"""@en ;
    obo:IAO_0000117 "person:Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Conversations with Barry Smith, Werner Ceusters, Bjoern Peters, Michel Dumontier, Melanie Courtot, James Malone, Bill Hogan"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:comment ""@en ;
    rdfs:label "denotes"@en ;
    rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000221
    obo:IAO_0000115 "m is a quality measurement of q at t. When q is a quality, there is a measurement process p that has specified output m, a measurement datum, that is about q"@en ;
    obo:IAO_0000116 "8/6/2009 Alan Ruttenberg: The strategy is to be rather specific with this relationship. There are other kinds of measurements that are not of qualities, such as those that measure time. We will add these as separate properties for the moment and see about generalizing later"@en, """From the second IAO workshop [Alan Ruttenberg 8/6/2009: not completely current, though bringing in comparison is probably important]

This one is the one we are struggling with at the moment. The issue is what a measurement measures. On the one hand saying that it measures the quality would include it \"measuring\" the bearer = referring to the bearer in the measurement. However this makes comparisons of two different things not possible. On the other hand not having it inhere in the bearer, on the face of it, breaks the audit trail.

Werner suggests a solution based on \"Magnitudes\" a proposal for which we are awaiting details.
--
From the second IAO workshop, various comments, [commented on by Alan Ruttenberg 8/6/2009]

unit of measure is a quality, e.g. the length of a ruler.

[We decided to hedge on what units of measure are, instead talking about measurement unit labels, which are the information content entities that are about whatever measurement units are. For IAO we need that information entity in any case. See the term measurement unit label]

[Some struggling with the various subflavors of is_about. We subsequently removed the relation represents, and describes until and only when we have a better theory]

a represents b means either a denotes b or a describes

describe:
a describes b means a is about b and a allows an inference of at least one quality of b

We have had a long discussion about denotes versus describes."""@en, """From the second IAO workshop: An attempt at tieing the quality to the measurement datum more carefully.

a is a magnitude means a is a determinate quality particular inhering in some bearer b existing at a time t that can be represented/denoted by an information content entity e that has parts denoting a unit of measure, a number, and b. The unit of measure is an instance of the determinable quality."""@en, """From the second meeting on IAO:

An attempt at defining assay using Barry's \"reliability\" wording

assay:
process and has_input some material entity
and has_output some information content entity 
and which is such that instances of this process type reliably generate 
outputs that describes the input."""@en, """This one is the one we are struggling with at the moment. The issue is what a measurement measures. On the one hand saying that it measures the quality would include it \"measuring\" the bearer = referring to the bearer in the measurement. However this makes comparisons of two different things not possible. On the other hand not having it inhere in the bearer, on the face of it, breaks the audit trail.

Werner suggests a solution based on \"Magnitudes\" a proposal for which we are awaiting details."""@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "is quality measurement of"@en ;
    rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000224
    obo:IAO_0000115 "Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ;
    obo:IAO_0000231 obo:IAO_0000226 ;
    a owl:NamedIndividual ;
    rdfs:label "obsolete_core"@en ;
    owl:deprecated true .

obo:IAO_0000225
    obo:IAO_0000111 "obsolescence reason specification"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ;
    obo:IAO_0000116 "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ;
    a owl:Class ;
    rdfs:label "obsolescence reason specification"@en ;
    rdfs:subClassOf obo:IAO_0000102 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:oneOf (obo:IAO_0000103
            obo:IAO_0000226
            obo:IAO_0000227
            obo:IAO_0000228
            obo:IAO_0000229
        )
    ] .

obo:IAO_0000226
    obo:IAO_0000111 "placeholder removed"@en ;
    a obo:IAO_0000225, owl:NamedIndividual ;
    rdfs:label "placeholder removed"@en .

obo:IAO_0000227
    obo:IAO_0000111 "terms merged"@en ;
    obo:IAO_0000116 "An editor note should explain what were the merged terms and the reason for the merge."@en ;
    a obo:IAO_0000225, owl:NamedIndividual ;
    rdfs:label "terms merged"@en .

obo:IAO_0000228
    obo:IAO_0000111 "term imported"@en ;
    obo:IAO_0000116 "This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use."@en ;
    a obo:IAO_0000225, owl:NamedIndividual ;
    rdfs:label "term imported"@en .

obo:IAO_0000229
    obo:IAO_0000111 "term split"@en ;
    obo:IAO_0000116 "This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created."@en ;
    a obo:IAO_0000225, owl:NamedIndividual ;
    rdfs:label "term split"@en .

obo:IAO_0000231
    obo:IAO_0000111 "has obsolescence reason"@en ;
    obo:IAO_0000115 "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ;
    obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Melanie Courtot"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "has obsolescence reason"@en .

obo:IAO_0000232
    obo:IAO_0000111 "curator note"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An administrative note of use for a curator but of no use for a user"@en ;
    obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "curator note"@en .

obo:IAO_0000233
    obo:IAO_0000111 "term tracker item"@en ;
    obo:IAO_0000112 "the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "An IRI or similar locator for a request or discussion of an ontology term."@en ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:comment "The 'tracker item' can associate a tracker with a specific ontology term."@en ;
    rdfs:label "term tracker item"@en .

obo:IAO_0000234
    obo:IAO_0000111 "ontology term requester"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:comment "The 'term requester' can credit the person, organization or project who request the ontology term." ;
    rdfs:label "ontology term requester"@en .

obo:IAO_0000235
    obo:IAO_0000115 "inverse of the relation 'denotes'"@en ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert, Mike Conlon"@en ;
    obo:IAO_0000233 <https://github.com/information-artifact-ontology/IAO/issues/206> ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "denoted by"@en .

obo:IAO_0000300
    obo:IAO_0000111 "textual entity"@en ;
    obo:IAO_0000112 "Words, sentences, paragraphs, and the written (non-figure) parts of publications are all textual entities"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc."@en ;
    obo:IAO_0000116 "AR, (IAO call 2009-09-01): a document as a whole is not typically a textual entity, because it has pictures in it - rather there are parts of it that are textual entities. Examples: The title, paragraph 2 sentence 7, etc."@en, "MC, 2009-09-14 (following IAO call 2009-09-01): textual entities live at the FRBR (http://en.wikipedia.org/wiki/Functional_Requirements_for_Bibliographic_Records) manifestation level. Everything is significant: line break, pdf and html versions of same document are different textual entities."@en ;
    obo:IAO_0000117 "PERSON: Lawrence Hunter"@en ;
    obo:IAO_0000118 "text"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "textual entity"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000305
    obo:IAO_0000111 "document title"@en ;
    obo:IAO_0000112 "Textual characteristics of traditional and Open Access scientific journals are similar"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A textual entity that names a document"@en ;
    obo:IAO_0000117 "PERSON: Lawrence Hunter"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "document title"@en ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000308
    obo:IAO_0000111 "figure"@en ;
    obo:IAO_0000112 "Any picture, diagram or table"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something."@en ;
    obo:IAO_0000117 "PERSON: Lawrence Hunter"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "figure"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000310
    obo:IAO_0000111 "document"@en ;
    obo:IAO_0000112 "A journal article, patent application, laboratory notebook, or a book"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A collection of information content entities intended to be understood together as a whole"@en ;
    obo:IAO_0000117 "PERSON: Lawrence Hunter"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "document"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000329
    obo:IAO_0000111 "running title"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A shorter version of a document title"@en ;
    obo:IAO_0000117 "PERSON: Lawrence Hunter"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "running title"@en ;
    rdfs:subClassOf obo:IAO_0000305 .

obo:IAO_0000408
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A scalar measurement datum that is the result of measurement of length quality"@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "length measurement datum"@en ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_0000409
    obo:IAO_0000111 "denotator type"@en ;
    obo:IAO_0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities."@en ;
    obo:IAO_0000115 "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Barry Smith, Werner Ceusters"@en ;
    a owl:Class ;
    rdfs:label "denotator type"@en ;
    rdfs:subClassOf obo:IAO_0000102 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:oneOf (obo:IAO_0000410
            obo:IAO_0000420
            obo:IAO_0000421
        )
    ] .

obo:IAO_0000410
    obo:IAO_0000111 "universal"@en ;
    obo:IAO_0000116 "Hard to give a definition for. Intuitively a \"natural kind\" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents."@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000119 "A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf"@en ;
    a obo:IAO_0000409, owl:NamedIndividual ;
    rdfs:label "universal"@en .

obo:IAO_0000411
    obo:IAO_0000111 "is denotator type"@en ;
    obo:IAO_0000115 "Relates an class defined in an ontology, to the type of it's denotator"@en ;
    obo:IAO_0000116 "In OWL 2 add AnnotationPropertyRange('is denotator type' 'denotator type')"@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "is denotator type"@en .

obo:IAO_0000412
    obo:IAO_0000111 "imported from"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "For external terms/classes, the ontology from which the term was imported"@en ;
    obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Melanie Courtot"@en ;
    obo:IAO_0000119 "GROUP:OBI:<http://purl.obolibrary.org/obo/obi>"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "imported from"@en .

obo:IAO_0000413
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "relates a process to a time-measurement-datum that represents the duration of the process"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "is duration of"@en ;
    rdfs:subPropertyOf obo:IAO_0000136 .

obo:IAO_0000414
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A scalar measurement datum that is the result of measurement of mass quality"@en ;
    obo:IAO_0000116 "2009/09/28 Alan Ruttenberg. Fucoidan-use-case"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "mass measurement datum"@en ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_0000416
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A scalar measurement datum that is the result of measuring a temporal interval"@en ;
    obo:IAO_0000116 "2009/09/28 Alan Ruttenberg. Fucoidan-use-case"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "time measurement datum"@en ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:IAO_0000417
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "inverse of the relation of is quality measurement of"@en ;
    obo:IAO_0000116 "2009/10/19 Alan Ruttenberg. Named 'junk' relation useful in restrictions, but not a real instance relationship"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "is quality measured as"@en .

obo:IAO_0000420
    obo:IAO_0000111 "defined class"@en ;
    obo:IAO_0000115 "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en ;
    obo:IAO_0000116 "\"definitions\", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal."@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    a obo:IAO_0000409, owl:NamedIndividual ;
    rdfs:label "defined class"@en .

obo:IAO_0000421
    obo:IAO_0000111 "named class expression"@en ;
    obo:IAO_0000115 "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en ;
    obo:IAO_0000116 "named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions"@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    a obo:IAO_0000409, owl:NamedIndividual ;
    rdfs:label "named class expression"@en .

obo:IAO_0000422
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A textual entity that is used as directive to deliver something to a person, or organization" ;
    obo:IAO_0000116 "2010-05-24 Alan Ruttenberg. Use label for the string representation. See issue https://github.com/information-artifact-ontology/IAO/issues/59" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "postal address"@en ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:IAO_0000423
    obo:IAO_0000111 "to be replaced with external ontology term"@en ;
    obo:IAO_0000115 "Terms with this status should eventually replaced with a term from another ontology."@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000119 "group:OBI"@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "to be replaced with external ontology term"@en .

obo:IAO_0000424
    obo:IAO_0000111 "expand expression to"@en ;
    obo:IAO_0000112 """ObjectProperty: RO_0002104
Label: has plasma membrane part
Annotations: IAO_0000424 \"http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)\"
"""@en ;
    obo:IAO_0000115 "A macro expansion tag applied to an object property (or possibly a data property)  which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ;
    obo:IAO_0000117 "Chris Mungall"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "expand expression to"@en .

obo:IAO_0000425
    obo:IAO_0000111 "expand assertion to"@en ;
    obo:IAO_0000112 """ObjectProperty: RO???
Label: spatially disjoint from
Annotations: expand_assertion_to \"DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X)  (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)\"
"""@en ;
    obo:IAO_0000115 "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ;
    obo:IAO_0000117 "Chris Mungall"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "expand assertion to"@en .

obo:IAO_0000426
    obo:IAO_0000111 "first order logic expression"@en ;
    obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "first order logic expression"@en .

obo:IAO_0000427
    obo:IAO_0000111 "antisymmetric property"@en ;
    obo:IAO_0000112 "part_of antisymmetric property xsd:true"@en ;
    obo:IAO_0000115 "Use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "antisymmetric property"@en .

obo:IAO_0000428
    obo:IAO_0000111 "requires discussion"@en ;
    obo:IAO_0000115 "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000119 "group:OBI"@en ;
    a obo:IAO_0000078, owl:NamedIndividual ;
    rdfs:label "requires discussion"@en .

obo:IAO_0000429
    obo:IAO_0000111 "email address"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000116 "Alan Ruttenberg 1/3/2012 - Provisional id, see issue at https://github.com/information-artifact-ontology/IAO/issues/130&thanks=130&ts=1325636583"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en, "Person:Chris Stoeckart"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "email address"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000572
    obo:IAO_0000112 "Recording the current temperature in a laboratory notebook. Writing a journal article. Updating a patient record in a database."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A planned process in which a document is created or added to by including the specified input in it."@en ;
    obo:IAO_0000116 "6/11/9: Edited at OBI workshop. We need to be able identify a child form of information artifact which corresponds to something enduring (not brain like). This used to be restricted to physical document or digital entity as the output, but that excludes e.g. an audio cassette tape"@en ;
    obo:IAO_0000117 "Bjoern Peters"@en ;
    obo:IAO_0000119 "wikipedia http://en.wikipedia.org/wiki/Documenting"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "documenting"@en ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:IAO_0000577
    obo:IAO_0000112 "The sentence \"The article has Pubmed ID 12345.\" contains a CRID that has two parts: one part is the CRID symbol, which is '12345'; the other part denotes the CRID registry, which is Pubmed."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bill Hogan"@en, "PERSON: Bjoern Peters"@en, "PERSON: Melanie Courtot"@en ;
    obo:IAO_0000118 "CRID symbol" ;
    obo:IAO_0000119 "Original proposal from Bjoern, discussions at IAO calls"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "centrally registered identifier symbol"@en ;
    rdfs:subClassOf obo:IAO_0000028 .

obo:IAO_0000578
    obo:IAO_0000112 "The sentence \"The article has Pubmed ID 12345.\" contains a CRID that has two parts: one part is the CRID symbol, which is '12345'; the other part denotes the CRID registry, which is Pubmed."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An information content entity that consists of a CRID symbol and additional information about the CRID registry to which it belongs."@en ;
    obo:IAO_0000116 "2014-05-05: In defining this term we take no position on what the CRID denotes. In particular do not assume it denotes a *record* in the CRID registry (since the registry might not have 'records')."@en, "Alan, IAO call 20101124: potentially the CRID denotes the instance it was associated with during creation."@en, "Note, IAO call 20101124: URIs are not always CRID, as not centrally registered. We acknowledge that CRID is a subset of a larger identifier class, but this subset fulfills our current needs. OBI PURLs are CRID as they are registered with OCLC. UPCs (Universal Product Codes from AC Nielsen)are not CRID as they are not centrally registered."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bill Hogan"@en, "PERSON: Bjoern Peters"@en, "PERSON: Melanie Courtot"@en ;
    obo:IAO_0000118 "CRID" ;
    obo:IAO_0000119 "Original proposal from Bjoern, discussions at IAO calls"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "centrally registered identifier"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:IAO_0000579
    obo:IAO_0000112 "PubMed is a CRID registry. It has a dataset of PubMed identifiers associated with journal articles. "@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A CRID registry is a dataset of CRID records, each consisting of a CRID symbol and additional information which was recorded in the dataset through a assigning a centrally registered identifier process."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bill Hogan"@en, "PERSON: Bjoern Peters"@en, "PERSON: Melanie Courtot"@en ;
    obo:IAO_0000118 "CRID registry" ;
    obo:IAO_0000119 "Original proposal from Bjoern, discussions at IAO calls"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "centrally registered identifier registry"@en ;
    rdfs:subClassOf obo:IAO_0000100 .

obo:IAO_0000581
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "relates a time stamped measurement datum to the time measurement datum that denotes the time when the measurement was taken"@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has time stamp"@en ;
    rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000582
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "time stamped measurement datum"@en ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:IAO_0000583
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "relates a time stamped measurement datum to the measurement datum that was measured"@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has measurement datum"@en ;
    rdfs:subPropertyOf obo:BFO_0000051 .

obo:IAO_0000589
    obo:IAO_0000111 "OBO foundry unique label"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "An alternative name for a class or property which is unique across the OBO Foundry."@en ;
    obo:IAO_0000116 "The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools ."@en ;
    obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Bjoern Peters"@en, "PERSON:Chris Mungall"@en, "PERSON:Melanie Courtot"@en ;
    obo:IAO_0000119 "GROUP:OBO Foundry <http://obofoundry.org/>"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "OBO foundry unique label"@en .

obo:IAO_0000596
    obo:IAO_0000111 "has ID digit count"@en ;
    obo:IAO_0000112 """Ontology: <http://purl.obolibrary.org/obo/ro/idrange/>
  Annotations: 
     'has ID prefix': \"http://purl.obolibrary.org/obo/RO_\"
     'has ID digit count' : 7,
     rdfs:label \"RO id policy\"
     'has ID policy for': \"RO\""""@en ;
    obo:IAO_0000115 "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "has ID digit count"@en .

obo:IAO_0000597
    obo:IAO_0000111 "has ID range allocated"@en ;
    obo:IAO_0000112 """Datatype: idrange:1
Annotations: 'has ID range allocated to': \"Chris Mungall\"
EquivalentTo: xsd:integer[> 2151 , <= 2300]
"""@en ;
    obo:IAO_0000115 "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "has ID range allocated to"@en .

obo:IAO_0000598
    obo:IAO_0000111 "has ID policy for"@en ;
    obo:IAO_0000112 """Ontology: <http://purl.obolibrary.org/obo/ro/idrange/>
  Annotations: 
     'has ID prefix': \"http://purl.obolibrary.org/obo/RO_\"
     'has ID digit count' : 7,
     rdfs:label \"RO id policy\"
     'has ID policy for': \"RO\""""@en ;
    obo:IAO_0000115 "Relating an ontology used to record id policy to the ontology namespace whose policy it manages"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "has ID policy for"@en .

obo:IAO_0000599
    obo:IAO_0000111 "has ID prefix"@en ;
    obo:IAO_0000112 """Ontology: <http://purl.obolibrary.org/obo/ro/idrange/>
  Annotations: 
     'has ID prefix': \"http://purl.obolibrary.org/obo/RO_\"
     'has ID digit count' : 7,
     rdfs:label \"RO id policy\"
     'has ID policy for': \"RO\""""@en ;
    obo:IAO_0000115 "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created."@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "has ID prefix"@en .

obo:IAO_0000600
    obo:IAO_0000111 "elucidation"@en ;
    obo:IAO_0000117 "person:Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Person:Barry Smith"@en ;
    obo:IAO_0000600 "Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "elucidation"@en .

obo:IAO_0000601
    obo:IAO_0000111 "has associated axiom(nl)"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000600 "An axiom associated with a term expressed using natural language"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "has associated axiom(nl)"@en .

obo:IAO_0000602
    obo:IAO_0000111 "has associated axiom(fol)"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000600 "An axiom expressed in first order logic using CLIF syntax"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "has associated axiom(fol)"@en .

obo:IAO_0000603
    obo:IAO_0000111 "is allocated id range"@en ;
    obo:IAO_0000115 "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ;
    obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:comment "Add as annotation triples in the granting ontology"@en ;
    rdfs:label "is allocated id range"@en .

obo:IAO_0000646
    obo:IAO_0000115 "An identifier that denotes some postal delivery route, some aggregate of postal delivery routes or a geographical region and was created for the purpose of sorting and delivering mail."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl> ;
    a owl:Class ;
    rdfs:label "postal code"@en ;
    rdfs:subClassOf obo:IAO_0020000 .

obo:IAO_0000700
    obo:IAO_0000111 "has ontology root term"@en ;
    obo:IAO_0000115 "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ;
    obo:IAO_0000117 "Nicolas Matentzoglu"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "has ontology root term"@en .

obo:IAO_0006011
    obo:IAO_0000111 "may be identical to"@en ;
    obo:IAO_0000115 "A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged."@en ;
    obo:IAO_0000117 "David Osumi-Sutherland"@en ;
    obo:IAO_0000233 "#40"@en ;
    obo:IAO_0000234 "VFB"@en ;
    a owl:AnnotationProperty ;
    rdfs:comment "Edges asserting this should be annotated with to record evidence supporting the assertion and its provenance."@en ;
    rdfs:label "may be identical to"@en .

obo:IAO_0006012
    obo:IAO_0000111 "scheduled for obsoletion on or after"@en ;
    obo:IAO_0000115 "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en ;
    obo:IAO_0000117 "Chris Mungall, Jie Zheng"@en ;
    obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/15532"@en, "https://github.com/information-artifact-ontology/ontology-metadata/issues/32"@en ;
    obo:IAO_0000234 "GO ontology"@en ;
    a owl:AnnotationProperty ;
    rdfs:label "scheduled for obsoletion on or after"@en ;
    rdfs:range xsd:dateTime .

obo:IAO_0010000
    obo:IAO_0000111 "has axiom id"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000600 "A URI that is intended to be unique label for an axiom used for tracking change to the ontology. For an axiom expressed in different languages, each expression is given the same URI"@en ;
    a owl:AnnotationProperty ;
    rdfs:isDefinedBy <http://purl.obolibrary.org/obo/iao.owl> ;
    rdfs:label "has axiom label"@en .

obo:IAO_0020000
    obo:IAO_0000111 "identifier"@en ;
    obo:IAO_0000115 "An identifier is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000118 "proper name"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/iao.owl>, <http://purl.obolibrary.org/obo/iao/pno.owl> ;
    a owl:Class ;
    rdfs:comment "Sep 29, 2016: The current definition has been amended from the previous version: \"A proper name is an information content entity that is the outcome of a dubbing process and is used to refer to one instance of entity shared by a group of people to refer to that individual entity.\" to more accuratly reflect the necessary and sufficient condition on the class. (MB)"@en ;
    rdfs:label "identifier"@en ;
    rdfs:subClassOf obo:IAO_0000030 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:IAO_0020012 ;
                owl:someValuesFrom obo:BFO_0000001
            ]
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:IAO_0020010 ;
                owl:onProperty obo:OBI_0000312
            ]
        )
    ] .

obo:IAO_0020010
    obo:IAO_0000115 "A dubbing process is a planned process that provides a reference to an individual entity shared by a group of subscribers to refer to that individual entity."@en ;
    obo:IAO_0000117 "Mathias Brochhausen", "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "dubbing process"@en ;
    rdfs:subClassOf obo:OBI_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:IAO_0020000
    ] .

obo:IAO_0020012
    obo:IAO_0000115 "x designates y, if for any given group of language users, x is an information content entity, is about y, and represents y in a linguistic context.."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:AsymmetricProperty, owl:IrreflexiveProperty, owl:ObjectProperty ;
    rdfs:domain obo:IAO_0000030 ;
    rdfs:label "designates"@en ;
    rdfs:range obo:BFO_0000001 ;
    owl:inverseOf obo:IAO_0020018 .

obo:IAO_0020015
    obo:IAO_0000115 "A personal name is a proper name identifying an individual person."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Personal_name"@en ;
    a owl:Class ;
    rdfs:comment "Personal names \"today usually comprises a given name bestowed at birth or at a young age plus a surname. It is nearly universal for a human to have a name; except in rare cases, for example feral children growing up in isolation, or infants orphaned by natural disaster for whom no written record survives.[citation needed] The Convention on the Rights of the Child specifies that a child has the right from birth to a name. Certain isolated tribes, such as the Machiguenga of the Amazon, also lack personal names.\" (http://en.wikipedia.org/wiki/Personal_name)"@en ;
    rdfs:label "personal name"@en ;
    rdfs:subClassOf obo:IAO_0020000 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0020000
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:NCBITaxon_9606 ;
                owl:onProperty obo:IAO_0020012
            ]
        )
    ] .

obo:IAO_0020016
    obo:IAO_0000115 "A given name, in Western contexts often referred to as a first name, is a personal name that specifies and differentiates between members of a group of individuals, especially in a family, all of whose members usually share the same family name (surname). A given name is purposefully given, usually by a child's parents at or near birth, in contrast to an inherited one such as a family name"@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Given_name" ;
    a owl:Class ;
    rdfs:label "given name"@en ;
    rdfs:subClassOf obo:IAO_0020015, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000050 ;
        owl:someValuesFrom obo:IAO_0020015
    ] .

obo:IAO_0020017
    obo:IAO_0000115 "A family name (in Western contexts often referred to as a surname or last name) is typically a part of a person's name which has been passed, according to law or custom, from one or both parents to their children."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Family_name" ;
    a owl:Class ;
    rdfs:label "family name"@en ;
    rdfs:subClassOf obo:IAO_0020015, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000050 ;
        owl:someValuesFrom obo:IAO_0020015
    ] .

obo:IAO_0020018
    obo:IAO_0000115 "p1 is designated by p2, if p2 is an information content entity that represents p1 in a linguistic context."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:AsymmetricProperty, owl:IrreflexiveProperty, owl:ObjectProperty ;
    rdfs:label "is designated by"@en .

obo:IAO_0020021
    obo:IAO_0000115 "A document that denotes some identity and is concretized by the bearer of some credential role."@en ;
    obo:IAO_0000117 "Amanda Hicks" ;
    a owl:Class ;
    rdfs:label "identity document"@en ;
    rdfs:subClassOf obo:IAO_0000310 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000310
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom obo:IAO_0020022
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000058 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000020
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000053 ;
                                owl:someValuesFrom obo:IAO_0020024
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:allValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000020
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000053 ;
                                owl:someValuesFrom obo:IAO_0020024
                            ]
                        ]
                    )
                ] ;
                owl:onProperty obo:RO_0000058
            ]
        )
    ] .

obo:IAO_0020022
    obo:IAO_0000115 "A documented identity is the aggregate of all data items about an entity.  Notice that a documented identity is not itself a document since a document is intended to be understood as a whole and data items about an individual are usually scattered across different documents."@en ;
    obo:IAO_0000117 "Amanda Hicks" ;
    a owl:Class ;
    rdfs:comment """is an aggregate of ICEs also an ICE? yes
Is part_of the appropriate relation to use for data items and documented identities?"""@en ;
    rdfs:label "documented identity"@en ;
    rdfs:subClassOf obo:IAO_0000030, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom obo:IAO_0000030
            ]
            [
                a owl:Restriction ;
                owl:onProperty [
                    owl:inverseOf obo:IAO_0000136
                ] ;
                owl:someValuesFrom obo:IAO_0020021
            ]
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:IAO_0000030 ;
                owl:onProperty obo:BFO_0000051
            ]
        )
    ] .

obo:IAO_0020023
    obo:IAO_0000112 " I order a beer and the bartender authenticates my age by looking at my DOB on my driver's license.  I sign into my email account, and the system authenticates my permission to read the email by checking the password I enter against my password listed in the database." ;
    obo:IAO_0000115 """Authentication is the act of checking or verifying an identity claim (that is either tacit or explicit).
"""@en ;
    obo:IAO_0000117 "Amanda Hicks" ;
    a owl:Class ;
    rdfs:label "authentication"@en ;
    rdfs:subClassOf obo:BFO_0000015, [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000015
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom obo:IAO_0020024
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000057 ;
                owl:someValuesFrom obo:IAO_0000027
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000057 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty [
                        owl:inverseOf obo:IAO_0000136
                    ] ;
                    owl:someValuesFrom obo:IAO_0000027
                ]
            ]
        )
    ] .

obo:IAO_0020024
    obo:IAO_0000115 "A role that inheres in a concretization of an identity document and is realized by an authentication process."@en ;
    obo:IAO_0000117 "Amanda Hicks"@en ;
    a owl:Class ;
    rdfs:label "credential role"@en ;
    rdfs:subClassOf obo:BFO_0000023 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000023
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000054 ;
                owl:someValuesFrom obo:IAO_0020023
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000052 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000053 ;
                    owl:someValuesFrom [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0000059 ;
                        owl:someValuesFrom obo:IAO_0020021
                    ]
                ]
            ]
        )
    ] .

obo:IAO_0100001
    obo:IAO_0000111 "term replaced by"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"@en ;
    obo:IAO_0000119 "Person:Alan Ruttenberg"@en ;
    a owl:AnnotationProperty ;
    rdfs:comment "Add as annotation triples in the granting ontology"@en ;
    rdfs:label "term replaced by"@en .

obo:IAO_8000000
    obo:IAO_0000111 "ontology module"@en ;
    obo:IAO_0000116 "I have placed this under 'data about an ontology part', but this can be discussed. I think this is OK if 'part' is interpreted reflexively, as an ontology module is the whole ontology rather than part of it."@en ;
    obo:IAO_0000118 "ontology file"@en ;
    obo:IAO_0000232 "This class and it's subclasses are applied to OWL ontologies. Using an rdf:type triple will result in problems with OWL-DL. I propose that dcterms:type is instead used to connect an ontology URI with a class from this hierarchy. The class hierarchy is not disjoint, so multiple assertions can be made about a single ontology."@en ;
    a owl:Class ;
    rdfs:label "ontology module"@en ;
    rdfs:subClassOf obo:IAO_0000102 .

obo:IAO_8000001
    obo:IAO_0000111 "base ontology module"@en ;
    obo:IAO_0000115 "An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies."@en ;
    a owl:Class ;
    rdfs:label "base ontology module"@en ;
    rdfs:seeAlso <https://github.com/INCATools/ontology-starter-kit/issues/50> ;
    rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000002
    obo:IAO_0000111 "editors ontology module"@en ;
    obo:IAO_0000115 "An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users."@en ;
    obo:IAO_0000118 "source ontology module"@en ;
    a owl:Class ;
    rdfs:label "editors ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000003
    obo:IAO_0000111 "main release ontology module"@en ;
    obo:IAO_0000115 "An ontology module that is intended to be the primary release product and the one consumed by the majority of tools."@en ;
    obo:IAO_0000116 "TODO: Add logical axioms that state that a main release ontology module is derived from (directly or indirectly) an editors module"@en ;
    a owl:Class ;
    rdfs:label "main release ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000004
    obo:IAO_0000111 "bridge ontology module"@en ;
    obo:IAO_0000115 "An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module."@en ;
    a owl:Class ;
    rdfs:label "bridge ontology module"@en ;
    rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/inter-anatomy-ontology-bridge-ontologies> ;
    rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000005
    obo:IAO_0000111 "import ontology module"@en ;
    obo:IAO_0000115 "A subset ontology module that is intended to be imported from another ontology."@en ;
    obo:IAO_0000116 "TODO: add axioms that indicate this is the output of a module extraction process."@en ;
    obo:IAO_0000118 "import file"@en ;
    a owl:Class ;
    rdfs:label "import ontology module"@en ;
    rdfs:seeAlso <http://robot.obolibrary.org/extract> ;
    rdfs:subClassOf obo:IAO_8000006 .

obo:IAO_8000006
    obo:IAO_0000111 "subset ontology module"@en ;
    obo:IAO_0000115 "An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms."@en ;
    obo:IAO_0000118 "ontology slim"@en, "subset ontology"@en ;
    a owl:Class ;
    rdfs:label "subset ontology module"@en ;
    rdfs:seeAlso <http://robot.obolibrary.org/filter>, <http://www.geneontology.org/page/go-slim-and-subset-guide> ;
    rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000007
    obo:IAO_0000111 "curation subset ontology module"@en ;
    obo:IAO_0000115 "A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation."@en ;
    a owl:Class ;
    rdfs:label "curation subset ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000006 .

obo:IAO_8000008
    obo:IAO_0000111 "analysis ontology module"@en ;
    obo:IAO_0000115 "An ontology module that is intended for usage in analysis or discovery applications."@en ;
    a owl:Class ;
    rdfs:label "analysis subset ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000006 .

obo:IAO_8000009
    obo:IAO_0000111 "single layer ontology module"@en ;
    obo:IAO_0000115 "A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint."@en ;
    obo:IAO_0000118 "ribbon subset"@en ;
    a owl:Class ;
    rdfs:label "single layer subset ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000006 .

obo:IAO_8000010
    obo:IAO_0000111 "exclusion subset ontology module"@en ;
    obo:IAO_0000115 "A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes."@en ;
    obo:IAO_0000118 "antislim"@en ;
    a owl:Class ;
    rdfs:label "exclusion subset ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000006 .

obo:IAO_8000011
    obo:IAO_0000111 "external import ontology module"@en ;
    obo:IAO_0000115 "An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach."@en ;
    obo:IAO_0000118 "external import"@en ;
    a owl:Class ;
    rdfs:label "external import ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000005 .

obo:IAO_8000012
    obo:IAO_0000111 "species subset ontology module"@en ;
    obo:IAO_0000115 "A subset ontology that is crafted to either include or exclude a taxonomic grouping of species."@en ;
    obo:IAO_0000118 "taxon subset"@en ;
    a owl:Class ;
    rdfs:label "species subset ontology module"@en ;
    rdfs:seeAlso <https://github.com/obophenotype/uberon/wiki/Taxon-constraints> ;
    rdfs:subClassOf obo:IAO_8000006 .

obo:IAO_8000013
    obo:IAO_0000111 "reasoned ontology module"@en ;
    obo:IAO_0000115 "An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available."@en ;
    a owl:Class ;
    rdfs:label "reasoned ontology module"@en ;
    rdfs:seeAlso <http://robot.obolibrary.org/reason> ;
    rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000014
    obo:IAO_0000111 "generated ontology module"@en ;
    obo:IAO_0000115 "An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV."@en ;
    obo:IAO_0000116 "TODO: Add axioms (using PROV-O?) that indicate this is the output-of some reasoning process"@en ;
    a owl:Class ;
    rdfs:label "generated ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000000 .

obo:IAO_8000015
    obo:IAO_0000111 "template generated ontology module"@en ;
    obo:IAO_0000115 "An ontology module that is automatically generated from a template specification and fillers for slots in that template."@en ;
    a owl:Class ;
    rdfs:label "template generated ontology module"@en ;
    rdfs:seeAlso <http://robot.obolibrary.org/template>, <https://doi.org/10.1186/s13326-017-0126-0>, <https://github.com/dosumis/dead_simple_owl_design_patterns/> ;
    rdfs:subClassOf obo:IAO_8000014 .

obo:IAO_8000016
    obo:IAO_0000111 "taxonomic bridge ontology module"@en ;
    a owl:Class ;
    rdfs:label "taxonomic bridge ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000004 .

obo:IAO_8000017
    obo:IAO_0000111 "ontology module subsetted by expressivity"@en ;
    a owl:Class ;
    rdfs:label "ontology module subsetted by expressivity"@en ;
    rdfs:subClassOf obo:IAO_8000006 .

obo:IAO_8000018
    obo:IAO_0000111 "obo basic subset ontology module"@en ;
    obo:IAO_0000115 """A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.

Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).

An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports"""@en ;
    a owl:Class ;
    rdfs:label "obo basic subset ontology module"@en ;
    rdfs:seeAlso <http://owlcollab.github.io/oboformat/doc/obo-syntax.html#6.2> ;
    rdfs:subClassOf obo:IAO_8000017 .

obo:IAO_8000019
    obo:IAO_0000111 "ontology module subsetted by OWL profile"@en ;
    a owl:Class ;
    rdfs:label "ontology module subsetted by OWL profile"@en ;
    rdfs:subClassOf obo:IAO_8000017 .

obo:IAO_8000020
    obo:IAO_0000111 "EL++ ontology module"@en ;
    a owl:Class ;
    rdfs:label "EL++ ontology module"@en ;
    rdfs:subClassOf obo:IAO_8000019 .

obo:ICO_0000001
    obo:IAO_0000115 "A document that explains all relevant information to assist a human being in understanding the expectations and requirements of participation in a process, and is an instrument in obtaining consent and, after having obtained consent, is a record that such a consent has occurred."@en ;
    obo:IAO_0000118 "informed consent document"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ico.owl> ;
    a owl:Class ;
    rdfs:label "informed consent form"@en ;
    rdfs:subClassOf obo:IAO_0000310 .

obo:ICO_0000023
    obo:IAO_0000115 "An informed consent form that has been filled with all required contents."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ico.owl> ;
    a owl:Class ;
    rdfs:label "completely filled informed consent form"@en ;
    rdfs:subClassOf obo:ICO_0000001, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBIB_0000018
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom obo:OBIB_0000017
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000057 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:NCBITaxon_9606
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBIB_0000012
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000057 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:NCBITaxon_9606
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000093
                            ]
                        )
                    ]
                ]
            )
        ]
    ] .

obo:ICO_0000024
    obo:IAO_0000115 "An informed consent form that has been partially filled with required contents."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ico.owl> ;
    a owl:Class ;
    rdfs:label "partially filled informed consent form"@en ;
    rdfs:subClassOf obo:ICO_0000001, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBIB_0000018
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom obo:OBIB_0000017
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000057 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:NCBITaxon_9606
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBIB_0000012
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000057 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:NCBITaxon_9606
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000093
                            ]
                        )
                    ]
                ]
            )
        ]
    ] .

obo:ICO_0000046
    obo:IAO_0000115 "A planned process of making the decision of the competent authorities in form of a letter, document, or verbal or electronic form, that confirms that somebody has permission to do something or be somewhere, e.g. to realize a given project."@en ;
    obo:IAO_0000118 "permission"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ico.owl> ;
    a owl:Class ;
    rdfs:label "act of authorizing"@en ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:ICO_0000075
    obo:IAO_0000115 "A document that is the output of an authorization process."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ico.owl> ;
    a owl:Class ;
    rdfs:label "obsolete authorization document"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000310 .

obo:ICO_0000146
    obo:IAO_0000115 "A role that represents the eligibility of a candidate according to a study protocol."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ico.owl> ;
    a owl:Class ;
    rdfs:label "eligibility of candidate participation"@en ;
    rdfs:subClassOf obo:BFO_0000017 .

obo:ICO_0000147
    obo:IAO_0000115 "A role inhering in a participant who meets all eligibility criteria defined within a study protocol."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ico.owl> ;
    a owl:Class ;
    rdfs:label "candidate eligible for study role"@en ;
    rdfs:subClassOf obo:ICO_0000146 .

obo:ICO_0000148
    obo:IAO_0000115 "A role inhering in a participant who does not meet all eligibility criteria defined within the study protocol."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ico.owl> ;
    a owl:Class ;
    rdfs:label "candidate ineligible for study role"@en ;
    rdfs:subClassOf obo:ICO_0000146 .

obo:IDO_0000450
    obo:IAO_0000115 "A disposition to initiate processes that result in a disorder."@en ;
    obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ;
    obo:IAO_0000118 "pathogenicity"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:comment "A pathogenic disposition is realized in processes that create a disorder.", "The use of 'initiates' is intended to convey that a pathogenic disposition is realized when processes resulting in a disorder begin because of some action on the part of the bearer of the disposition.  By this interpretation of 'initiates', disorder-causing entities such as glass, UV light, and toxins do not have a pathogenic disposition." ;
    rdfs:label "pathogenic disposition"@en ;
    rdfs:subClassOf obo:BFO_0000016, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:RO_0000052 ;
                owl:someValuesFrom obo:BFO_0000040
            ]
            [
                a owl:Restriction ;
                owl:allValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000015
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0002297 ;
                            owl:someValuesFrom obo:OGMS_0000045
                        ]
                    )
                ] ;
                owl:onProperty obo:BFO_0000054
            ]
        )
    ] .

obo:IDO_0000456
    obo:IAO_0000115 "An organism that is experiencing pregnancy-induced or pathologic immunosuppression."@en ;
    obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "immunosuppressed organism"@en ;
    rdfs:subClassOf obo:OBI_0100026 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0100026
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000056 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:unionOf (obo:IDO_0000612
                        obo:IDO_0000644
                    )
                ]
            ]
        )
    ] .

obo:IDO_0000528
    obo:IAO_0000115 "A material entity with a pathogenic disposition."@en ;
    obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "pathogen"@en ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000091 ;
                owl:someValuesFrom obo:IDO_0000450
            ]
        )
    ] .

obo:IDO_0000610
    obo:IAO_0000115 "A process that attenuates an immune response."@en ;
    obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "immunosuppression"@en ;
    rdfs:subClassOf obo:BFO_0000015 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000015
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0002212 ;
                owl:someValuesFrom obo:GO_0006955
            ]
        )
    ] .

obo:IDO_0000612
    obo:IAO_0000115 "An immunosuppression process which arises as the result of a disorder."@en ;
    obo:IAO_0000116 "Disorders that result in immunosuppression include those that result from infection, stress, malnutrition, and treatments such as chemotherapy or calcineurin inhibition."@en ;
    obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "pathologic immunosuppression"@en ;
    rdfs:subClassOf obo:IDO_0000610 .

obo:IDO_0000619
    obo:IAO_0000115 "A disposition whose realization negatively regulates an immune response."@en ;
    obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "immunosuppressive disposition"@en ;
    rdfs:subClassOf obo:BFO_0000016 .

obo:IDO_0000644
    obo:IAO_0000115 "An immunosuppression induced by progesterone and other factors upregulated in pregnant women."@en ;
    obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "pregnancy-induced immunosuppression"@en ;
    rdfs:subClassOf obo:IDO_0000610 .

obo:IDO_0000660
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "results_in"@en .

obo:IDO_0001008
    obo:IAO_0000115 "An immunosuppressed organism that is a human experiencing HIV-based immunosuppression." ;
    obo:IAO_0000117 "Alex Diehl", "Lindsay Cowell" ;
    obo:IAO_0000234 "NCI BBRB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "immunosuppressed human experiencing HIV-based immunosuppression"@en ;
    rdfs:subClassOf obo:IDO_0000456 .

obo:IDO_0001013
    obo:IAO_0000115 "An immunosuppressed organism that is a human experiencing chronic systemic steroid use-based immunosuppression." ;
    obo:IAO_0000117 "Alex Diehl", "Lindsay Cowell" ;
    obo:IAO_0000234 "NCI BBRB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "immunosuppressed human experiencing chronic systemic steroid use-based immunosuppression"@en ;
    rdfs:subClassOf obo:IDO_0000456 .

obo:IDO_0001014
    obo:IAO_0000115 "A pathologically immunosuppressed organism that is a human experiencing drug-based immunosuppression." ;
    obo:IAO_0000117 "Alex Diehl", "Lindsay Cowell" ;
    obo:IAO_0000234 "NCI BBRB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ido.owl> ;
    a owl:Class ;
    rdfs:label "immunosuppressed human experiencing drug-based immunosuppression due to organ transplant"@en ;
    rdfs:subClassOf obo:IDO_0000456 .

obo:NCBITaxon_10239
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Viruses"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0100026 .

obo:NCBITaxon_10292
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Herpesviridae"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_10239 .

obo:NCBITaxon_10358
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Cytomegalovirus"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_10292 .

obo:NCBITaxon_10376
    obo:IAO_0000118 "Epstein Barr virus"^^xsd:string, "Epstein-Barr virus"^^xsd:string, "Epstein-Barr virus EBV"^^xsd:string, "Human herpesvirus 4"^^xsd:string, "Human herpesvirus type 4"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Human gammaherpesvirus 4"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_10292 .

obo:NCBITaxon_10407
    obo:IAO_0000118 "Human hepatitis B virus"^^xsd:string, "hepatitis B virus (HBV)"^^xsd:string, "hepatitis B virus HBV"^^xsd:string, "hepatitis B virus, HBV"^^xsd:string, "human hepatitis B virus HBV"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Hepatitis B virus"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_10239 .

obo:NCBITaxon_11103
    obo:IAO_0000118 "Hepatitis C virus"^^xsd:string, "hepatitis C virus HCV"^^xsd:string, "human hepatitis C virus"^^xsd:string, "human hepatitis C virus HCV"^^xsd:string, "human hepatitis virus C HCV"^^xsd:string, "post-transfusion hepatitis non A non B virus"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Hepacivirus C"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_10239 .

obo:NCBITaxon_11646
    obo:IAO_0000118 "Lentivirinae"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Lentivirus"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_10239 .

obo:NCBITaxon_11676
    obo:IAO_0000118 "human immunodeficiency virus 1 HIV-1"^^xsd:string, "human immunodeficiency virus HIV-1"^^xsd:string, "human immunodeficiency virus type 1 HIV 1"^^xsd:string, "human immunodeficiency virus type 1 HIV1"^^xsd:string, "human immunodeficiency virus type 1, HIV-1"^^xsd:string, "human immunodeficiency virus type I HIV-1"^^xsd:string, "human immunodeficiency virus type-1 HIV-1"^^xsd:string, "human immunodeficiency virus-1 HIV-1"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Human immunodeficiency virus 1"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_11646 .

obo:NCBITaxon_11709
    obo:IAO_0000118 "HIV type 2"^^xsd:string, "Human immunodeficiency virus type 2"^^xsd:string, "Human immunodeficiency virus-2"^^xsd:string, "human immunodeficiency virus type 2 HIV-2"^^xsd:string, "human immunodeficiency virus type 2, HIV-2"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Human immunodeficiency virus 2"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_11646 .

obo:NCBITaxon_117571
    obo:IAO_0000118 "bony vertebrates"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Euteleostomi"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_7742 .

obo:NCBITaxon_2
    obo:IAO_0000118 "eubacteria"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Bacteria"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0100026 .

obo:NCBITaxon_2157
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Archaea"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0100026 .

obo:NCBITaxon_2759
    obo:IAO_0000118 "eucaryotes"^^xsd:string, "eukaryotes"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Eukaryota"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0100026 .

obo:NCBITaxon_314146
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Euarchontoglires"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_40674 .

obo:NCBITaxon_32523
    obo:IAO_0000118 "tetrapods"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Tetrapoda"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_117571 .

obo:NCBITaxon_32524
    obo:IAO_0000118 "amniotes"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Amniota"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_32523 .

obo:NCBITaxon_33154
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Opisthokonta"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_2759 .

obo:NCBITaxon_33213
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Bilateria"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_33154 .

obo:NCBITaxon_388799
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "HIV-1 group O"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_11676 .

obo:NCBITaxon_40674
    obo:IAO_0000118 "mammals"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Mammalia"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_32524 .

obo:NCBITaxon_7742
    obo:IAO_0000118 "Vertebrata"^^xsd:string, "vertebrates"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Vertebrata <vertebrates>"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_33213 .

obo:NCBITaxon_9606
    obo:IAO_0000118 "human"^^xsd:string, "man"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncbitaxon.owl> ;
    a owl:Class ;
    rdfs:label "Homo sapiens"^^xsd:string ;
    rdfs:subClassOf obo:NCBITaxon_314146 .

obo:NCIT_C106501
    obo:IAO_0000115 "The method by which conception or impregnation is prevented. This may be achieved through the use of devices, drugs or surgery." ;
    obo:IAO_0000118 "BCMETHOD", "Birth Control Method" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Birth Control Method" ;
    rdfs:subClassOf obo:IAO_0000104 .

obo:NCIT_C126303
    obo:IAO_0000115 "A rare, cytologically high grade carcinoma that arises from the renal parenchyma. It is characterized by the presence of prominently dilated cystic spaces in a bland, fibrotic stroma. The lining cells have large irregular nuclei with prominent nucleoli and abundant eosinophilic cytoplasm. Necrosis and mitotic figures are not present. It rarely metastasizes." ;
    obo:IAO_0000118 "Tubulocystic Renal Cell Cancer", "Tubulocystic Renal Cell Carcinoma", "Tubulocystic renal cell carcinoma" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Tubulocystic Renal Cell Carcinoma" ;
    rdfs:subClassOf obo:DOID_4451 .

obo:NCIT_C126528
    obo:IAO_0000115 "Denotes a person whose ancestry is in any of the countries of the central part of the African continent: Burundi, the Central African Republic, Chad, the Democratic Republic of the Congo, and Rwanda." ;
    obo:IAO_0000118 "Central African" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Central African" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C126529
    obo:IAO_0000115 "Denotes a person whose ancestry is in any of the countries of the northern part of the African continent: Algeria, Egypt, Libya, Morocco, Sudan, Tunisia, and Western Sahara." ;
    obo:IAO_0000118 "North African" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "North African" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C126530
    obo:IAO_0000115 "Denotes a person whose ancestry is in the country of South Africa." ;
    obo:IAO_0000118 "South African" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "South African" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C126533
    obo:IAO_0000115 "Denotes a person whose ancestry is in any of the Asian countries south of China, east of India, west of New Guinea and north of Australia." ;
    obo:IAO_0000118 "SOUTHEAST ASIAN", "Southeast Asian" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Southeast Asian" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C126534
    obo:IAO_0000115 "Denotes a person whose ancestry is in any of the Asian countries between the Caspian Sea in the west, China in the east, Afghanistan in the south, and Russia in the north." ;
    obo:IAO_0000118 "CENTRAL ASIAN", "Central Asian" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Central Asian" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C126535
    obo:IAO_0000115 "Denotes a person whose ancestry is in the country or continent of Australia." ;
    obo:IAO_0000118 "Australian" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Australian" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C126536
    obo:IAO_0000115 "Denotes a person whose ancestry is in the country of New Zealand." ;
    obo:IAO_0000118 "New Zealander" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "New Zealander" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C126538
    obo:IAO_0000115 "Denotes a person whose ancestry is in the countries of Scandinavia: Denmark, Norway and Sweden. Finland and Iceland are generally included as part of the Scandinavian region." ;
    obo:IAO_0000118 "Scandinavian" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Scandinavian" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C128458
    obo:IAO_0000115 "A collection of ethnic geographical categories including Australian and New Zealander." ;
    obo:IAO_0000118 "Australian/New Zealand", "Australian/New Zealand Ethnicity" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Australian/New Zealand Ethnicity" ;
    rdfs:subClassOf obo:HANCESTRO_0004 .

obo:NCIT_C15477
    obo:IAO_0000115 "An indicator that a person previously received radiation treatment for the same condition." ;
    obo:IAO_0000118 "Prior RT", "Prior Radiation", "Prior Radiation Therapy", "Prior Radiotherapy", "previously irradiated", "previously_irradiated" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Prior Radiation Therapy" ;
    rdfs:subClassOf obo:OGMS_0000090 .

obo:NCIT_C15675
    obo:IAO_0000115 "Any therapy that is administered to augment or stimulate other treatment modalities or to minimize or prevent disease recurrence subsequent to the main treatment plan." ;
    obo:IAO_0000118 "AJ-Adjuvant Therapy", "Adjuvant Therapy", "adjunct therapy", "adjunctive therapy", "adjuvant therapy" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Adjuvant Therapy" ;
    rdfs:subClassOf obo:NCIT_C16212 .

obo:NCIT_C16168
    obo:IAO_0000115 "Originally, therapeutic administration of serum or gamma globulin containing preformed antibodies produced by another individual; currently, immunotherapy includes nonspecific systemic stimulation, adjuvants, active specific immunotherapy, and adoptive immunotherapy.  New forms of immunotherapy include the use of monoclonal antibodies.  This approach has been widely adopted by cancer specialists, often in cases which fail to respond to other treatment.  Immunotherapy aims to boost immune system function, as with the administration of interferons and interleukin-2, or to attack cancerous cells directly, as with the injection of monoclonal antibodies.  Various immunotherapeutic techniques have also been employed among AIDS patients.  In addition, a number of alternative medical practices are claimed to enhance immune function, and various over-the-counter substances (e.g., goldenseal, lysine have gained popularity for this supposed property." ;
    obo:IAO_0000118 "Prior Immunotherapy" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Prior Immunotherapy" ;
    rdfs:subClassOf obo:OGMS_0000090 .

obo:NCIT_C16171
    obo:IAO_0000115 "Previous chemotherapy administered as treatment for this cancer." ;
    obo:IAO_0000118 "Prior Chemotherapy", "Prior Chemotherapy Regimens" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Prior Chemotherapy" ;
    rdfs:subClassOf obo:OGMS_0000090 .

obo:NCIT_C16175
    obo:IAO_0000115 "An indication that an individual has been previously treated with hormonal therapy." ;
    obo:IAO_0000118 "Prior Hormone Therapy", "prior hormonal therapy" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Prior Hormone Therapy" ;
    rdfs:subClassOf obo:OGMS_0000090 .

obo:NCIT_C16212
    obo:IAO_0000115 "Any intervention for management of a malignant neoplasm." ;
    obo:IAO_0000118 "Cancer Therapeutic Procedure", "Cancer Therapy", "Cancer Treatment", "Malignant Neoplasm Therapy", "Malignant Neoplasm Treatment", "anticancer therapy" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Cancer Therapeutic Procedure" ;
    rdfs:subClassOf obo:OGMS_0000090 .

obo:NCIT_C27891
    obo:IAO_0000115 "A group of renal cell carcinomas characterized by the presence of different translocations involving the chromosome Xp11.2. These translocations result in the creation of gene fusions involving the TFE3 gene. Patients are usually children and young adults. Morphologically, the malignant epithelial cells form papillary patterns." ;
    obo:IAO_0000118 "Renal Cell Cancer Associated with Xp11.2 Translocations/TFE3 Gene Fusions", "Renal Cell Carcinoma Associated with Xp11.2 Translocations/TFE3 Gene Fusions", "TFE3-Rearranged Renal Cell Carcinoma", "Xp11.2 Translocation-Related Renal Cell Carcinoma", "tRCC" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Renal Cell Carcinoma Associated with Xp11.2 Translocations/TFE3 Gene Fusions" ;
    rdfs:subClassOf obo:DOID_4451 .

obo:NCIT_C29719
    obo:IAO_0000115 "A record of an individual's background in regard to smoking tobacco. This would include such factors as start date, end date (if applicable), number of cigarette smoked, attempts to quit, and others." ;
    obo:IAO_0000118 "Smoking History", "Tobacco Smoking History", "Tobacco Use" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Tobacco Smoking History" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:NCIT_C40037
    obo:IAO_0000115 "A neoplasm of low malignant potential arising from the ovary.  It is characterized by the proliferation of neoplastic mucinous epithelial cells that resemble intestinal epithelial cells.  There is no evidence of stromal invasion." ;
    obo:IAO_0000118 "Borderline Ovarian Mucinous Tumor, Intestinal Type" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Borderline Ovarian Mucinous Tumor, Intestinal Type" ;
    rdfs:subClassOf obo:DOID_6067 .

obo:NCIT_C40038
    obo:IAO_0000115 "A neoplasm of low malignant potential arising from the ovary.  It is characterized by the proliferation of neoplastic epithelial cells that resemble endocervical epithelial cells.  There is no evidence of stromal invasion." ;
    obo:IAO_0000118 "Borderline Ovarian Mucinous Tumor, Endocervical-Like" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Borderline Ovarian Mucinous Tumor, Endocervical-Like" ;
    rdfs:subClassOf obo:DOID_6067 .

obo:NCIT_C40080
    obo:IAO_0000115 "An epithelial neoplasm with low malignant potential affecting the ovary.  It is characterized by the presence of clear or hobnail cells.  In some cases, the cells may display nuclear atypia and prominent nucleoli.  When such cells are present, they remain confined to the glands.  There is no evidence of stromal invasion." ;
    obo:IAO_0000118 "Borderline Ovarian Clear Cell Neoplasm", "Borderline Ovarian Clear Cell Tumor", "Clear cell cystic tumor of borderline malignancy" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Borderline Ovarian Clear Cell Tumor" ;
    rdfs:subClassOf obo:DOID_0050934 .

obo:NCIT_C40088
    obo:IAO_0000115 "An ovarian epithelial neoplasm that resembles the transitional cell neoplasms found in the urinary tract. It is characterized by the presence of atypia and absence of stromal invasion." ;
    obo:IAO_0000118 "Borderline Ovarian Transitional Cell Neoplasm", "Borderline Ovarian Transitional Cell Tumor" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Borderline Ovarian Transitional Cell Tumor" ;
    rdfs:subClassOf obo:DOID_4000 .

obo:NCIT_C41263
    obo:IAO_0000115 "Denotes a person whose ancestry is in the countries of the Indian sub-continent, including India, Pakistan, Bangladesh, and Sri Lanka." ;
    obo:IAO_0000118 "SOUTH ASIAN", "South Asian", "South Asians" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "South Asian" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C43851
    obo:IAO_0000115 "Denotes the inhabitants of any of the countries of Europe, a person from there, or their descendants elsewhere." ;
    obo:IAO_0000118 "EUROPEAN", "European" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "European" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C4509
    obo:IAO_0000115 "An aggressive carcinoma arising from the ovary.  Most patients present with advanced disease.  Microscopically, it is characterized by significant cytologic atypia, increased mitotic activity, and necrosis.  The prognosis is usually poor." ;
    obo:IAO_0000118 "Anaplastic Carcinoma of Ovary", "Anaplastic Carcinoma of the Ovary", "Anaplastic Ovarian Carcinoma", "Ovarian Undifferentiated Carcinoma", "Undifferentiated Carcinoma of Ovary", "Undifferentiated Carcinoma of the Ovary", "Undifferentiated Ovarian Cancer", "Undifferentiated Ovarian Carcinoma" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Ovarian Undifferentiated Carcinoma" ;
    rdfs:subClassOf obo:DOID_2394 .

obo:NCIT_C45502
    obo:IAO_0000115 "A morphologic variant of squamous cell lung carcinoma characterized by the presence of papillary structures." ;
    obo:IAO_0000118 "Lung Squamous Cell Carcinoma, Papillary Variant", "Squamous Cell Lung Carcinoma, Papillary Variant" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Lung Squamous Cell Carcinoma, Papillary Variant" ;
    rdfs:subClassOf obo:DOID_3907 .

obo:NCIT_C45503
    obo:IAO_0000115 "A morphologic variant of squamous cell lung carcinoma characterized by the presence of clear cells." ;
    obo:IAO_0000118 "Lung Squamous Cell Carcinoma, Clear Cell Variant", "Squamous Cell Lung Carcinoma, Clear Cell Variant" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Lung Squamous Cell Carcinoma, Clear Cell Variant" ;
    rdfs:subClassOf obo:DOID_3907 .

obo:NCIT_C45504
    obo:IAO_0000115 "A poorly differentiated morphologic variant of squamous cell lung carcinoma characterized by the presence of small tumor cells with focal squamous differentiation." ;
    obo:IAO_0000118 "Lung Squamous Cell Carcinoma, Small Cell Variant", "Squamous Cell Lung Carcinoma, Small Cell Variant" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Lung Squamous Cell Carcinoma, Small Cell Variant" ;
    rdfs:subClassOf obo:DOID_3907 .

obo:NCIT_C45512
    obo:IAO_0000115 "A morphologic variant of lung adenocarcinoma characterized by the presence of mucin pools containing islands of well differentiated adenocarcinoma cells." ;
    obo:IAO_0000118 "Lung Colloid Adenocarcinoma", "Lung Mucinous Cystadenocarcinoma", "Lung Mucinous Cystic Tumor of Borderline Malignancy", "Mucinous cystic tumor of borderline malignancy" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Lung Colloid Adenocarcinoma" ;
    rdfs:subClassOf obo:DOID_3910 .

obo:NCIT_C45514
    obo:IAO_0000115 "A morphologic variant of lung adenocarcinoma characterized by the presence of signet ring cells." ;
    obo:IAO_0000118 "Lung Signet Ring Cell Carcinoma" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Lung Signet Ring Cell Carcinoma" ;
    rdfs:subClassOf obo:DOID_3910 .

obo:NCIT_C5226
    obo:IAO_0000115 "A low grade serous epithelial neoplasm arising from the ovary.  It is characterized by an atypical proliferation of serous-type epithelial cells without evidence of stromal invasion.  It is often asymptomatic but rarely it may present with abdominal pain or abdominal enlargement due to rupture or torsion." ;
    obo:IAO_0000118 "Borderline Ovarian Serous Neoplasm", "Borderline Ovarian Serous Tumor", "Borderline Serous Neoplasm of Ovary", "Borderline Serous Neoplasm of the Ovary", "Borderline Serous Tumor of Ovary", "Borderline Serous Tumor of the Ovary", "Ovarian Serous Neoplasm of Low Malignant Potential", "Ovarian Serous Tumor of Low Malignant Potential", "Proliferating Ovarian Serous Neoplasm", "Proliferating Ovarian Serous Tumor", "Proliferating Serous Neoplasm of Ovary", "Proliferating Serous Neoplasm of the Ovary", "Proliferating Serous Tumor of Ovary", "Proliferating Serous Tumor of the Ovary", "Serous Neoplasm of Ovary with Low Malignant Potential", "Serous Neoplasm of the Ovary with Low Malignant Potential", "Serous Ovarian Neoplasm of Low Malignant Potential", "Serous Ovarian Tumor of Low Malignant Potential", "Serous Tumor of Ovary with Low Malignant Potential", "Serous Tumor of the Ovary with Low Malignant Potential" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Borderline Ovarian Serous Tumor" ;
    rdfs:subClassOf obo:DOID_0050933 .

obo:NCIT_C5651
    obo:IAO_0000115 "A morphologic variant of lung adenocarcinoma characterized by the presence of polygonal malignant cells forming sheets. Acinar, papillary, micropapillary, or lepidic growth patterns are absent.  If the tumor is 100 percent solid, intracellular mucin should be present in at least five tumor cells in each of two high-power fields and confirmed with mucin immunohistochemical stains. Tumors formerly classified as large cell carcinomas expressing pneumocyte immunohistochemical markers, even if intracellular mucin is absent, are now included in this category." ;
    obo:IAO_0000118 "Lung Solid Adenocarcinoma with Mucin", "Pulmonary Solid Adenocarcinoma with Mucin", "Solid Adenocarcinoma of Lung with Mucin", "Solid Adenocarcinoma of the Lung with Mucin", "Solid Lung Adenocarcinoma", "Solid adenocarcinoma" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Solid Lung Adenocarcinoma" ;
    rdfs:subClassOf obo:DOID_3910 .

obo:NCIT_C7100
    obo:IAO_0000115 "An invasive malignant epithelial tumor that arises from the colon.  There is no morphologic, immunophenotypic, or molecular biological evidence of glandular or squamous differentiation." ;
    obo:IAO_0000118 "Carcinoma Simplex of the Colon.", "Colon Anaplastic Carcinoma", "Colon Undifferentiated Carcinoma", "Undifferentiated Carcinoma of Colon", "Undifferentiated Carcinoma of the Colon", "Undifferentiated Colon Cancer", "Undifferentiated Colonic Carcinoma" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Colon Undifferentiated Carcinoma" ;
    rdfs:subClassOf obo:DOID_1520 .

obo:NCIT_C7281
    obo:IAO_0000115 "A low grade, non-invasive mixed epithelial proliferative neoplasm that arises from the ovary. It is composed predominantly of serous and endocervical-type mucinous cells." ;
    obo:IAO_0000118 "Borderline Ovarian Seromucinous Tumor/Atypical Proliferative Ovarian Seromucinous Tumor" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Borderline Ovarian Seromucinous Tumor/Atypical Proliferative Ovarian Seromucinous Tumor" ;
    rdfs:subClassOf obo:DOID_2152 .

obo:NCIT_C73993
    obo:IAO_0000115 "A quantification of lifetime tobacco exposure defined as (number of cigarettes smoked per day x number of years smoked)/20. One pack-year is smoking 20 cigarettes a day for one year." ;
    obo:IAO_0000118 "Pack Year", "Pack Year: The number of cigarettes smoked per day times the number of years smoked divided by 20 (the number of cigarettes in a pack)", "Pack-Year", "pack year", "{Pack Year}" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Pack Year" ;
    rdfs:subClassOf obo:IAO_0000003 .

obo:NCIT_C77811
    obo:IAO_0000115 "Denotes a person having origins in any of the countries abutting the Mediterranean Sea, principally those of Europe." ;
    obo:IAO_0000118 "MEDITERRANEAN", "Mediterranean" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Mediterranean" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C77817
    obo:IAO_0000115 "Denotes a person having origins in any of the countries of Western Europe such as Spain, Portugal, or France." ;
    obo:IAO_0000118 "WESTERN EUROPEAN", "Western European" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Western European" ;
    rdfs:subClassOf obo:NCIT_C43851 .

obo:NCIT_C77819
    obo:IAO_0000115 "Denotes a person having origins in any of the countries of Eastern Europe such as Czechoslovakia, Poland, Croatia, Hungary, Slovenia, Former Soviet Union, or Finland. It also includes persons who call themselves Gypsies from this region." ;
    obo:IAO_0000118 "EASTERN EUROPEAN", "Eastern European" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Eastern European" ;
    rdfs:subClassOf obo:NCIT_C43851 .

obo:NCIT_C77820
    obo:IAO_0000115 "Denotes a person having origins in the region of southwest Asia, between the India subcontinent and Europe, including Kuwait, Turkey, Lebanon, Israel, Iraq, Iran, Jordan, Saudi Arabia, lands east of Pakistan or the other countries of the Arabian Peninsula.  Also includes people of Jewish ethnicity including Sephardic and Ashkenazic." ;
    obo:IAO_0000118 "MIDDLE EASTERN", "Middle Eastern" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Middle Eastern" ;
    rdfs:subClassOf obo:OBI_0000181 .

obo:NCIT_C7983
    obo:IAO_0000115 "An epithelial neoplasm that arises from the ovary characterized by the presence of glandular or cystic spaces which contain atypical glandular epithelial cells resembling endometrial cells. The surrounding ovarian stroma is often fibrotic. There is no evidence of stromal invasion." ;
    obo:IAO_0000118 "Borderline Endometrioid Neoplasm of Ovary", "Borderline Endometrioid Neoplasm of the Ovary", "Borderline Endometrioid Tumor of Ovary", "Borderline Endometrioid Tumor of the Ovary", "Borderline Ovarian Endometrioid Neoplasm", "Borderline Ovarian Endometrioid Tumor", "Borderline Ovarian Endometrioid Tumor/Atypical Proliferative Ovarian Endometrioid Tumor", "EBT/APET", "Endometrioid Neoplasm of Low Malignant Potential", "Endometrioid Neoplasm with Proliferating Activity, Ovarian", "Endometrioid Tumor of Low Malignant Potential", "Endometrioid Tumor with Proliferating Activity, Ovarian", "Endometrioid tumor of low malignant potential", "Low Malignant Potential Endometrioid Neoplasm of Ovary", "Low Malignant Potential Endometrioid Neoplasm of the Ovary", "Low Malignant Potential Endometrioid Tumor of Ovary", "Low Malignant Potential Endometrioid Tumor of the Ovary", "Low Malignant Potential Ovarian Endometrioid Neoplasm", "Low Malignant Potential Ovarian Endometrioid Tumor", "Ovarian Endometrioid Borderline Neoplasm", "Ovarian Endometrioid Borderline Tumor", "Ovarian Endometrioid Neoplasm of Low Malignant Potential", "Ovarian Endometrioid Neoplasm with Proliferating Activity", "Ovarian Endometrioid Tumor of Low Malignant Potential", "Ovarian Endometrioid Tumor with Proliferating Activity", "Proliferating Endometrioid Neoplasm of Ovary", "Proliferating Endometrioid Neoplasm of the Ovary", "Proliferating Endometrioid Tumor of Ovary", "Proliferating Endometrioid Tumor of the Ovary", "Proliferating Ovarian Endometrioid Neoplasm", "Proliferating Ovarian Endometrioid Tumor" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Borderline Ovarian Endometrioid Tumor/Atypical Proliferative Ovarian Endometrioid Tumor" ;
    rdfs:subClassOf obo:DOID_5828 .

obo:NCIT_C81229
    obo:IAO_0000115 "A description of an individual's current and past experience with alcoholic beverage consumption." ;
    obo:IAO_0000118 "Alcohol History", "Alcohol Use", "Alcohol Use History" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ncit.owl> ;
    a owl:Class ;
    rdfs:label "Alcohol Use History" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OAE_0001159
    obo:IAO_0000115 "A surgery that is a surgical procedure to remove all or part of your colon." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/oae.owl> ;
    a owl:Class ;
    rdfs:label "colectomy" ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000000
    obo:IAO_0000115 "A textual entity providing information about a biobank and that is written in English."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000118 "biobank description"@en ;
    a owl:Class ;
    rdfs:label "biobank description in english"@en ;
    rdfs:subClassOf obo:IAO_0000300, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom obo:OBIB_0000616
    ] .

obo:OBIB_0000001
    obo:IAO_0000115 "A proper name that refers to a sample collection."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "sample collection identifier"@en ;
    rdfs:subClassOf obo:IAO_0020000 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0020000
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0020012 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000027
                        [
                            a owl:Restriction ;
                            owl:allValuesFrom obo:OBI_0100051 ;
                            owl:onProperty obo:BFO_0000051
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000010
    obo:IAO_0000115 "A device that is part of a freezer and consists of a solid horizontal surface to keep material in the freezer on a flat surface."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "freezer shelf"@en ;
    rdfs:subClassOf obo:OBI_0000968, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000399
    ] .

obo:OBIB_0000011
    obo:IAO_0000115 "A planned process that gets rid of a material that is no longer useful or desirable."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "discarding"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000040
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0001025 ;
                    owl:someValuesFrom obo:OBIB_0000014
                ]
            )
        ]
    ] .

obo:OBIB_0000012
    obo:IAO_0000115 "A worker role of recruiting human subjects to partcipate in a clinical investigation in which data about human subject is collected."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "human subject recuiter role"@en ;
    rdfs:subClassOf obo:OBI_0000116 .

obo:OBIB_0000013
    obo:IAO_0000115 "A device that is intended to hold cryovials."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "cryovial box"@en ;
    rdfs:subClassOf obo:OBI_0000967, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000370
    ] .

obo:OBIB_0000014
    obo:IAO_0000115 "A container that is used for discarded material."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "trash container"@en ;
    rdfs:subClassOf obo:OBI_0000967, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000370
    ] .

obo:OBIB_0000015
    obo:IAO_0000115 "A device that is part of a freezer for keeping material in the freezer in a defined position and prevents movement."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "freezer rack"@en ;
    rdfs:subClassOf obo:OBI_0000968, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000399
    ] .

obo:OBIB_0000016
    obo:IAO_0000115 "A device that is designed to contain blood spot cards."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "blood spot card box"@en ;
    rdfs:subClassOf obo:OBI_0000967, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000370
    ] .

obo:OBIB_0000017
    obo:IAO_0000115 "A questionnaire that comprises a set of questions about patient, such as height, weight, race, biological sex, clinical history, etc., which will be filled by a recruiter based on an Electronic Medical Record (EMR)."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "data confirm questionnaire"@en ;
    rdfs:subClassOf obo:OBI_0001000 .

obo:OBIB_0000018
    obo:IAO_0000115 "A document editing process in which one or more fields in a form are filled with related information, such as when answering a questionnare."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "form filling"@en ;
    rdfs:subClassOf obo:OBI_0302908 .

obo:OBIB_0000019
    obo:IAO_0000115 "A patient questionnaire which has been filled out by a patient."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "filled patient questionnaire"@en ;
    rdfs:subClassOf obo:OBIB_0000020, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBIB_0000018
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom obo:OBIB_0000020
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000057 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:NCBITaxon_9606
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000093
                            ]
                        )
                    ]
                ]
            )
        ]
    ] .

obo:OBIB_0000020
    obo:IAO_0000115 "A questionnaire that comprises a set of demographic and medical questions about a patient which will be filled by the patient or their legally authorized representative."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "patient questionnaire"@en ;
    rdfs:subClassOf obo:OBI_0001000 .

obo:OBIB_0000021
    obo:IAO_0000115 "A collection packet which contains a container with a specimen and a form filled with information about the collected specimen and specimen source."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "collection packet with specimen and information material"@en ;
    rdfs:subClassOf obo:OBIB_0000024, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000040
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000053 ;
                    owl:someValuesFrom [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0000059 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:IAO_0000030
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:IAO_0000136 ;
                                    owl:someValuesFrom obo:OBI_0100051
                                ]
                            )
                        ]
                    ]
                ]
            )
        ]
    ] .

obo:OBIB_0000022
    obo:IAO_0000115 "A material to be added role that is born by a chemical entity which is added into a blood collection containter to optimize specific blood component(s) preservation and/or separation."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "blood additive role"@en ;
    rdfs:subClassOf obo:OBI_0000319 .

obo:OBIB_0000023
    obo:IAO_0000115 "A worker role that performs the practical hands-on work in laboratories and is realized during study design execution."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "lab technician role"@en ;
    rdfs:subClassOf obo:OBI_0000116 .

obo:OBIB_0000024
    obo:IAO_0000115 "A collection packet which contains a container with a specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "collection packet with specimen"@en ;
    rdfs:subClassOf obo:OBIB_0000028, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0100051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0001025 ;
                    owl:someValuesFrom obo:OBI_0000967
                ]
            )
        ]
    ] .

obo:OBIB_0000025
    obo:IAO_0000115 "A collection packet which contains an empty container that will be used for holding a specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "collection packet with empty container"@en ;
    rdfs:subClassOf obo:OBIB_0000028, [
        a owl:Restriction ;
        owl:onProperty <http://purl.obolibrary.org/obo/cl#lacks_part> ;
        owl:someValuesFrom obo:IAO_0000178
    ], [
        a owl:Restriction ;
        owl:onProperty <http://purl.obolibrary.org/obo/cl#lacks_part> ;
        owl:someValuesFrom obo:OBI_0100051
    ] .

obo:OBIB_0000026
    obo:IAO_0000115 "A role borne by some material entity which can be delivered/administrated into some organism and the role is realized during a clinical treatment process aiming to treat symptoms, signs or diagnosed disease."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "Penn Group"^^xsd:string ;
    obo:IAO_0000231 obo:IAO_0000228 ;
    obo:IAO_0000233 <https://github.com/biobanking/biobanking/issues/79> ;
    obo:IAO_0100001 obo:OGMS_0000148 ;
    a owl:Class ;
    rdfs:label "obsolete medication role"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OBIB_0000027
    obo:IAO_0000115 "A data confirm questionnaire which has been filled out by a human subject recruiter."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "filled data confirm questionnaire"@en ;
    rdfs:subClassOf obo:OBIB_0000017, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBIB_0000018
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom obo:OBIB_0000017
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000057 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:NCBITaxon_9606
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBIB_0000012
                            ]
                        )
                    ]
                ]
            )
        ]
    ] .

obo:OBIB_0000028
    obo:IAO_0000115 "A material entity used for specimen collection. It can contain a container to hold a specimen and material (e.g. paper) carrying information about the specimen and the specimen source (e.g. patient)."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "collection packet"@en ;
    rdfs:subClassOf obo:BFO_0000040, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:OBI_0000967
    ] .

obo:OBIB_0000029
    obo:IAO_0000115 "A material entity that is bearer of a medication role." ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Jie Zheng" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "medication material"@en ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OGMS_0000148
            ]
        )
    ] .

obo:OBIB_0000030
    obo:IAO_0000115 "A device that  is designed to collect, ship and store blood specimens in an easy and inexpensive way."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "blood spot card"@en ;
    rdfs:subClassOf obo:OBI_0000967, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000370
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000399
    ] .

obo:OBIB_0000031
    obo:IAO_0000115 "A test tube that designed to store materials at very low temperatures."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "cryovial"@en ;
    rdfs:subClassOf obo:OBI_0000967 .

obo:OBIB_0000032
    obo:IAO_0000115 "A test tube  which is either a sterile glass or plastic tube with a closure that is evacuated to create a vacuum inside the tube facilitating the draw of a predetermined volume of liquid. Most commonly used to draw a blood sample directly from the vein, these also are used to collect urine samples. Vacutainer tube may contain additives designed to stabilize and preserve the specimen prior to analytical testing."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Vacutainer" ;
    a owl:Class ;
    rdfs:label "vacutainer"@en ;
    rdfs:subClassOf obo:OBI_0000967 .

obo:OBIB_0000033
    obo:IAO_0000115 "A planned process for receiving specimens such as into a laboratory."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "specimen receiving"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBIB_0000028
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0001025 ;
                    owl:someValuesFrom <http://vivoweb.org/ontology/core#Laboratory>
                ]
            )
        ]
    ] .

obo:OBIB_0000034
    obo:IAO_0000115 "An adding a material entity into a target process where a collected specimen is added to a specimen container. (note, not used for other specimen process that produce new specimens)"^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "adding specimen into a container"@en ;
    rdfs:subClassOf obo:OBI_0000274, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0100051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000087 ;
                    owl:someValuesFrom obo:OBI_0000319
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0001025 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:OBI_0000967
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000444
                            ]
                        )
                    ]
                ]
            )
        ]
    ] .

obo:OBIB_0000035
    obo:IAO_0000115 "An adding specimen into a container process that spots the blood from an organism on the blood spot card."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "blood spotting"@en ;
    rdfs:subClassOf obo:OBIB_0000034, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0000655
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000057 ;
        owl:someValuesFrom obo:OBIB_0000030
    ] .

obo:OBIB_0000036
    obo:IAO_0000115 "A processed specimen which is the output of a density gradient centrifugation of an anticoagulated blood specimen that contains most of the white blood cells and platelets."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Buffy_coat" ;
    a owl:Class ;
    rdfs:label "buffy coat specimen"@en ;
    rdfs:subClassOf obo:OBI_0000953, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0302886
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom obo:OBI_0000655
                ]
            )
        ]
    ] .

obo:OBIB_0000037
    obo:IAO_0000115 "A relation that relates a container to a measurement datum that specifies the maximum capacity of the container."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:ObjectProperty ;
    rdfs:domain obo:OBI_0000967 ;
    rdfs:label "has maximum capacity"@en ;
    rdfs:range obo:IAO_0000109 .

obo:OBIB_0000038
    obo:IAO_0000115 "A relation that relates a container to a measurement datum that specifies the actual amount of material in the container."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:ObjectProperty ;
    rdfs:domain obo:OBI_0000967 ;
    rdfs:label "has actual load"@en ;
    rdfs:range obo:IAO_0000109 .

obo:OBIB_0000039
    obo:IAO_0000115 "A blood specimen that is located on a blood spot card."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:comment "A specimen that located in a blood spot card via blood spotting process." ;
    rdfs:label "blood specimen on blood spot card"@en ;
    rdfs:subClassOf obo:OBI_0000655, obo:OBI_0000953, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBIB_0000035
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001025 ;
        owl:someValuesFrom obo:OBIB_0000030
    ] .

obo:OBIB_0000040
    obo:IAO_0000115 "A collection packet which contains a container without a specimen and an unfilled form that will be used to fill in information about specimen to be collected."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "collection packet with empty container and unfilled information material"@en ;
    rdfs:subClassOf obo:OBIB_0000028, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000040
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000053 ;
                    owl:someValuesFrom [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0000059 ;
                        owl:someValuesFrom obo:IAO_0000030
                    ]
                ]
            )
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty <http://purl.obolibrary.org/obo/cl#lacks_part> ;
        owl:someValuesFrom obo:OBI_0100051
    ] .

obo:OBIB_0000041
    obo:IAO_0000115 "A duration time of smoking about how long a person has been smoking regularly. (better to have criteria of regularly mean, such as smoke everyday)"^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "duration time of smoking regularly"@en ;
    rdfs:subClassOf obo:OBIB_0000053 .

obo:OBIB_0000042
    obo:IAO_0000115 "An average value of use of cigarettes per day."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "average daily use of cigarette datum"@en ;
    rdfs:subClassOf obo:OBI_0000679, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0200170
    ] .

obo:OBIB_0000043
    obo:IAO_0000115 "A processed material that contains nicotine in the form of a transdermal patch which releases nicotine into the body through the skin. It is commonly used as an aid in nicotine replacement therapy (NRT), a process for smoking cessation."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Nicotine_patch" ;
    a owl:Class ;
    rdfs:label "nicotine patch"@en ;
    rdfs:subClassOf obo:OBIB_0000048, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:CHEBI_18723
    ] .

obo:OBIB_0000044
    obo:IAO_0000115 "A processed material which is a small cylinder of finely cut tobacco leaves rolled in thin paper for smoking."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Cigarette" ;
    a owl:Class ;
    rdfs:label "cigarette"@en ;
    rdfs:subClassOf obo:OBIB_0000048, obo:OBIB_0000057, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:CHEBI_18723
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom obo:OBIB_0000056
    ] .

obo:OBIB_0000045
    obo:IAO_0000115 "A processed material contains nicotine in a form of a chewing gum or a candy-like tablet. It delivers nicotine to the body via absorption by the tissues of the mouth.  It is commonly used as an aid in nicotine replacement therapy (NRT), a process for smoking cessation."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Nicotine_gum" ;
    a owl:Class ;
    rdfs:label "nicotine gum or lozenge"@en ;
    rdfs:subClassOf obo:OBIB_0000048, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:CHEBI_18723
    ] .

obo:OBIB_0000046
    obo:IAO_0000115 "A processed material which is a tightly-rolled bundle of dried and fermented tobacco that is ignited so that its smoke may be drawn into the mouth."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Cigar" ;
    a owl:Class ;
    rdfs:label "cigar"@en ;
    rdfs:subClassOf obo:OBIB_0000048, obo:OBIB_0000057, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:CHEBI_18723
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom obo:OBIB_0000056
    ] .

obo:OBIB_0000047
    obo:IAO_0000115 "A processed material which is a kind of smokeless tobacco product consumed by placing a portion of the tobacco between the cheek and gum or upper lip teeth and chewing."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Chewing_tobacco" ;
    a owl:Class ;
    rdfs:label "chewing tobacco"@en ;
    rdfs:subClassOf obo:OBIB_0000057, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom obo:OBIB_0000056
    ] .

obo:OBIB_0000048
    obo:IAO_0000115 "A processed material that contains nicotine."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000118 "nicotine product" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "nicotine material"@en ;
    rdfs:subClassOf obo:OBI_0000047 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000047
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom obo:CHEBI_18723
            ]
        )
    ] .

obo:OBIB_0000049
    obo:IAO_0000115 "A device made to allow the user to inhale or taste smoke or vapor derived from the burning or vaporization of some substance."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Smoking_pipe" ;
    a owl:Class ;
    rdfs:label "smoking pipe"@en ;
    rdfs:subClassOf obo:OBI_0000967, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000370
    ] .

obo:OBIB_0000050
    obo:IAO_0000115 "A processed material that vaporizes a liquid solution containing nicotine and simulates tobacco smoking by producing an aerosol that resembles smoke."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Electronic_cigarette" ;
    a owl:Class ;
    rdfs:label "nicotine e-cigarette"@en ;
    rdfs:subClassOf obo:OBIB_0000048, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:CHEBI_18723
    ] .

obo:OBIB_0000051
    obo:IAO_0000115 "A time measurement datum which is the start date of a smoking behavior."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "smoking start date"@en ;
    rdfs:subClassOf obo:IAO_0000416, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom <http://www.ebi.ac.uk/efo/EFO_0004318>
    ] .

obo:OBIB_0000052
    obo:IAO_0000115 "A smoking behavior that uses a smoking pipe to inhale or taste tobacco material."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "pipe smoking behavior"@en ;
    rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0004318>, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBIB_0000055
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000057 ;
        owl:someValuesFrom obo:OBIB_0000049
    ] .

obo:OBIB_0000053
    obo:IAO_0000115 "A time measurement datum about how long a person has been smoking."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "duration time of smoking"@en ;
    rdfs:subClassOf obo:IAO_0000416, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000413 ;
        owl:someValuesFrom <http://www.ebi.ac.uk/efo/EFO_0004318>
    ] .

obo:OBIB_0000054
    obo:IAO_0000115 "A time measurement datum which is the end date of a smoking behavior."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "smoking end date"@en ;
    rdfs:subClassOf obo:IAO_0000416, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom <http://www.ebi.ac.uk/efo/EFO_0004318>
    ] .

obo:OBIB_0000055
    obo:IAO_0000115 "A processed material which is made from tobacco for smoking tobacco using a pipe."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "pipe tobacco"@en ;
    rdfs:subClassOf obo:OBIB_0000057, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom obo:OBIB_0000056
    ] .

obo:OBIB_0000056
    obo:IAO_0000115 "A Eukaryota that is within the genus Nicotiana of the Solanaceae (nightshade) family."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "tobacco"@en ;
    rdfs:subClassOf obo:NCBITaxon_2759 .

obo:OBIB_0000057
    obo:IAO_0000115 "A processed material that is made from tobacco. Typically, tobacco material is meant to be used as a source of nicotine as tobacco contains a higher concentration of nicotine than most other plants."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert" ;
    obo:IAO_0000118 "tobacco product" ;
    obo:IAO_0000119 "Penn Group" ;
    a owl:Class ;
    rdfs:label "tobacco material"@en ;
    rdfs:subClassOf obo:OBI_0000047 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000047
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0001000 ;
                owl:someValuesFrom obo:OBIB_0000056
            ]
        )
    ] .

obo:OBIB_0000058
    obo:IAO_0000115 "An anatomical location that is just below (1 cm) the site of surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "Location below resection"^^xsd:string ;
    rdfs:subClassOf obo:FMA_50707 .

obo:OBIB_0000059
    obo:IAO_0000112 "adjacent to tissue for PAXgene fixation."^^xsd:string ;
    obo:IAO_0000115 "An anatomical location that is adjacent to the site where tissue was collected and subjected to fixation."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "Location adjacent to tissue fixation"^^xsd:string ;
    rdfs:subClassOf obo:FMA_50707 .

obo:OBIB_0000060
    obo:IAO_0000115 "A time measurement datum that states the duration during which a specimen was submerged in fixative."^^xsd:string ;
    obo:IAO_0000116 "more general than time in formalin"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time in fixative measurement"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000061
    obo:IAO_0000115 "A collection from organism that occurs after the organism is dead."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "postmortem collecting specimen from organism"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0600005 .

obo:OBIB_0000062
    obo:IAO_0000115 "A collecting specimen from organism that occurs during the process of organ donation."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "collecting specimen from organism during organ donation"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0600005 .

obo:OBIB_0000063
    obo:IAO_0000115 "A temperature measurement assay to obtain the body temperature of an organism through placement of a thermometer in an internal cavity or organ."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "core body temperature"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "internal body temperature measurement assay"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002140 .

obo:OBIB_0000065
    obo:IAO_0000115 "An internal body temperature measurement assay where the thermometer is placed in the rectum."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "rectal temperature measurement assay"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000063 .

obo:OBIB_0000066
    obo:IAO_0000115 "An internal body temperature measurement assay where the thermometer is placed in an organ."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "organ temperature measurement assay"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000063 .

obo:OBIB_0000067
    obo:IAO_0000115 "An internal body temperature measurement assay where the temperature probe interfaces with the anesthesia vent monitor. Typically the thermometer is a rectal probe with a wire and connector that hooks up to the ekg/pulse ox/co2 monitor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "anesthesia probe temperature measurement assay"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000063 .

obo:OBIB_0000068
    obo:IAO_0000115 "An identifier that refers to a collection packet used in a specimen collection process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Kit ID"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "collection packet identifier"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000069
    obo:IAO_0000115 "A role which inheres in a person and is realized in the dissection of a body for anatomical instruction or pathological examination."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://medical-dictionary.thefreedictionary.com/prosector"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "prosector role"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000070
    obo:IAO_0000115 "A protocol that is a set of step-by-step instructions compiled by an organization for carrying out routine operations."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "SOP"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Standard_operating_procedure"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "standard operating procedure"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000071
    obo:IAO_0000115 "A standard operating procedure for the transportation of specimens."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen transport SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000072
    obo:IAO_0000115 "A standard operating procedure for collecting specimens from organism."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "tissue procurement SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000073
    obo:IAO_0000115 "A standard operating procedure for properly and completely filling out a case report form."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "CRF completion protocol"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "case report form completion SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000074
    obo:IAO_0000115 "A textual entity that is a short communication to provide advisory or informative matter about a standard operating procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://www.merriam-webster.com/dictionary/memorandum"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "SOP memorandum"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000075
    obo:IAO_0000115 "A protocol that provides deviations or changes to part of an existing standard operating procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "SOP adjustment"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000076
    obo:IAO_0000115 "A date of specimen collection for the first collection of blood from a donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "first blood draw date"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000714 .

obo:OBIB_0000077
    obo:IAO_0000115 "A date of specimen collection for the first collection of a tissue from a donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "first tissue removed date"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000714 .

obo:OBIB_0000078
    obo:IAO_0000115 "A data item that reports the calendar date when the data collected on a form was verified."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of form data verification"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000079
    obo:IAO_0000115 "A data item that reports the time of day when a blood specimen was collected."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood draw time"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000080
    obo:IAO_0000115 "A blood draw time for the first collection of a blood specimen from a donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "first blood draw time"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000079 .

obo:OBIB_0000081
    obo:IAO_0000115 "A time of surgical removal of specimen for the first removal of tissue from a donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "first tissue removed time"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000725 .

obo:OBIB_0000082
    obo:IAO_0000115 "A data item that reports the time of day when a clamp or ligature was applied to an organ for specimen collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of surgical ligature for specimen collection"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000083
    obo:IAO_0000115 "A planned process to assess the correctness of data entered on a form."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "form data verification process"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000084
    obo:IAO_0000115 "A planned process to stop blood flow for an organ during a surgical procedure using a clamp or ligature."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "surgical ligature process"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000085
    obo:IAO_0000115 "An organization at which the process of collecting a specimen from an organism occurred."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "biospecimen source site"^^xsd:string, "tissue source site"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "organization conducting specimen collection from organism"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000245 .

obo:OBIB_0000086
    obo:IAO_0000112 "specimen collected with GTEx Pink Kit"^^xsd:string ;
    obo:IAO_0000115 "A specimen from organism that is collected with a collection packet that is designed to collect specimens of a particular type for a particular purpose."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "specimen collected with specific kit"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen collected with specific collection packet"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001479 .

obo:OBIB_0000087
    obo:IAO_0000115 "A categorical value specification that is used to record the destruction of an organism cells or tissues by the organisms' own enzymes or processes with nominal categories ranging from none to severe."^^xsd:string ;
    obo:IAO_0000116 "Add instances 0-non, 1-slight, 2-moderate, 3-severe"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "autolysis value specification"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBIB_0000088
    obo:IAO_0000112 "follow up needed for Pathology Resource Center identified issue for Postmortem/Organ Procurement Tissue Collection"^^xsd:string ;
    obo:IAO_0000115 "A data item that is an indicator of whether further followup on a specimen collection issue is required."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "followup required for specimen collection issue"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000089
    obo:IAO_0000112 "resolution of Pathology Resource Center identified issue for Postmortem/Organ Procurement Tissue Collection"^^xsd:string ;
    obo:IAO_0000115 "A data item that is an indicator of whether a specimen collection issue is resolved."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "resolved specimen collection issue"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000090
    obo:IAO_0000115 "A comment from tissue procurement that is an explanation as to why frozen specimens were not collected."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "reason for not collecting frozen specimens"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000091
    obo:IAO_0000115 "A comment from tissue procurement made in regards to the resolution of an issue with the tissue."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on resolved specimen collection issue"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000092
    obo:IAO_0000115 "A data item indicating whether the body of the specimen donor was refrigerated after death but prior to specimen collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor body refrigerated indicator"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000093
    obo:IAO_0000115 "A time measurement datum that states the duration during which the specimen donor's body was refrigerated."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time donor body refrigerated measurement"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000094
    obo:IAO_0000115 "A life-death temporal boundary marked by the irreversible end of all brain activity (including involuntary activity necessary to sustain life)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "brain death"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "cessation of brain activity death"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0035944 .

obo:OBIB_0000095
    obo:IAO_0000115 "A life-death temporal boundary marked by the natural cessation of cardiac activity."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "cardiac death"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "cessation of cardiac activity death"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0035944 .

obo:OBIB_0000096
    obo:IAO_0000115 "A data item that indicates the amount of a serum analyte is at a level above a threshold considered to be present."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "positive serological assay result"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000097
    obo:IAO_0000115 "A data item that indicates the amount of a serum analyte is at a level below a threshold considered to be present."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "negative serological assay result"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000098
    obo:IAO_0000115 "A data item that indicates the amount of a serum analyte is approximately at a threshold considered to be present and therefore can not be confidently scored as positive or negative."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indeterminate serological assay result"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000099
    obo:IAO_0000115 "An information content entity that is about the status of an assay and indicates that the assay has not been started or completed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "non-performance of an assay"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000100
    obo:IAO_0000115 "A date of specimen collection on which the surgery was performed during which the specimen was collected."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of surgical removal of specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000714 .

obo:OBIB_0000101
    obo:IAO_0000115 "A planned process to administer sedation drugs intravenously prior to surgery in order to induce total or partial loss of sensation especially tactile sensation and pain."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "preoperative intravenous administration of sedative"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000102
    obo:IAO_0000115 "A planned process to administer opioid analgesics intravenously prior to surgery in order to induce total or partial loss of sensation especially tactile sensation and pain."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "preoperative intravenous administration of opioid analgesic"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000103
    obo:IAO_0000115 "A planned process to administer antiemetic agents intravenously prior to surgery to prevent nausea or vomiting."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "preoperative intravenous administration of antiemetic"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000104
    obo:IAO_0000115 "A planned process to administer antacid intravenously prior to surgery  in order to relieve and reduce the symptoms of ulcers in the stomach and upper small intestine."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "preoperative intravenous administration of antacid"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000105
    obo:IAO_0000115 "A planned process to administer medication intravenously prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "preoperative intravenous administration of medication"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000106
    obo:IAO_0000112 "administered prior to organ removal"^^xsd:string ;
    obo:IAO_0000115 "A planned process to administer anaesthetic to a restricted or localized area in order to produce a loss of feeling."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of local anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000107
    obo:IAO_0000112 "epidural administration prior to organ removal"^^xsd:string ;
    obo:IAO_0000115 "A planned process to administer anaesthetic to a restricted area or part of the body in order to produce a loss of feeling."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of regional anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000108
    obo:IAO_0000112 "administered prior to organ removal"^^xsd:string ;
    obo:IAO_0000115 "A planned process to administer anaesthetic within or into a vein or veins in order to produce a loss of feeling."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of intravenous anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000109
    obo:IAO_0000112 "administered prior to organ removal"^^xsd:string ;
    obo:IAO_0000115 "A planned process to administer opioid analgesics intravenously in order to induce total or partial loss of sensation especially tactile sensation and pain."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "intravenous administration of opioid analgesic"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000110
    obo:IAO_0000112 "administered prior to organ removal"^^xsd:string ;
    obo:IAO_0000115 "A planned process to administer muscle relaxant intravenously in order to relax skeletal muscles and reduce muscle contraction."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "intravenous administration of muscle relaxant"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000111
    obo:IAO_0000112 "administered prior to organ removal"^^xsd:string ;
    obo:IAO_0000115 "A planned process to administer anaesthetic in the form of a gas aerosol or fine powder via the respiratory tract usually by oral or nasal inhalation for local or systemic effect."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of inhalation anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000112
    obo:IAO_0000115 "A planned process to administer anaesthetic in order to produce a loss of feeling."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of anaesthetic"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000113
    obo:IAO_0000115 "A planned process to administer insulin during a surgical procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of insulin during surgery"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000114
    obo:IAO_0000115 "A planned process to administer steroid during a surgical procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of steroid during surgery"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000115
    obo:IAO_0000115 "A planned process to administer antimicrobial agent(s) during a surgical procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of antimicrobial agent during surgery"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000116
    obo:IAO_0000115 "A planned process to administer medication(s) during a surgical procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "administration of medication during surgery"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000117
    obo:IAO_0000115 "A data item that reports the time of day at which the first incision is made during surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of first surgical incision"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000118
    obo:IAO_0000115 "A surgical procedure in which the anus, rectum, and sigmoid colon are removed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://my.clevelandclinic.org/health/articles/laparoscopic-abdominoperineal-resection-basic-surgical-steps"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "abdominoperineal resection"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000119
    obo:IAO_0000115 "A colectomy that is the surgical removal of the left side of the large intestine."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "left colectomy"^^xsd:string ;
    obo:IAO_0000119 "http://emedicine.medscape.com/article/1965606-overview"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left hemicolectomy"^^xsd:string ;
    rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000120
    obo:IAO_0000115 "A colectomy that is the surgical removal of the sigmoid colon."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://emedicine.medscape.com/article/1965606-overview"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "sigmoid colectomy"^^xsd:string ;
    rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000121
    obo:IAO_0000115 "A colectomy that involves removing the cecum, the ascending colon, the hepatic flexure (where the ascending colon joins the transverse colon), the first one-third of the transverse colon, and part of the terminal ileum, along with fat and lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "right colectomy"^^xsd:string ;
    obo:IAO_0000119 "http://emedicine.medscape.com/article/1535001-overview"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right hemicolectomy"^^xsd:string ;
    rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000122
    obo:IAO_0000115 "A colectomy that is complete resection of the colon"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Colectomy"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "subtotal colectomy"^^xsd:string ;
    rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000123
    obo:IAO_0000115 "A colectomy that is resection of part of the colon or a resection of all of the colon without complete resection of the colon"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Colectomy"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "total colectomy"^^xsd:string ;
    rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000124
    obo:IAO_0000115 "A colectomy that is resection of the transverse colon along with the middle colic vessels and its mesentery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://ether.stanford.edu/abdominal_surgery_rotation/documents/Colon%20surgeries%20vm%20071512.pdf"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "transverse colectomy"^^xsd:string ;
    rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000125
    obo:IAO_0000115 "A surgical procedure that is done to treat cancer of the rectum in which the part of the rectum containing the cancer is removed. The remaining part of the rectum is reconnected to the colon."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "LAR"^^xsd:string ;
    obo:IAO_0000119 "https://www.mskcc.org/cancer-care/patient-education/about-your-low-anterior-resection-surgery"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "low anterior resection"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000126
    obo:IAO_0000115 "A surgical procedure to remove all or part of the rectum. It is often needed to treat rectal cancer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.hopkinsmedicine.org/healthlibrary/test_procedures/gastroenterology/proctectomy_135,53/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "proctectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000127
    obo:IAO_0000115 "A colectomy that is the surgical removal of the rectum and all or part of the colon.["^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Proctocolectomy"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "proctocolectomy"^^xsd:string ;
    rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000128
    obo:IAO_0000115 "A colectomy that is the surgical removal of the rectum and sigmoid colon."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://medical-dictionary.thefreedictionary.com/rectosigmoidectomy"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "rectosigmoidectomy"^^xsd:string ;
    rdfs:subClassOf obo:OAE_0001159 .

obo:OBIB_0000129
    obo:IAO_0000115 "A data item that reports the time of day when the first clamp was applied to the vasculature of an organ for specimen collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of first clamp for specimen removal"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000130
    obo:IAO_0000115 "A data item that reports the time of day when the second clamp was applied to the vasculature of an organ for specimen collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of second clamp for specimen removal"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000131
    obo:IAO_0000115 "A time measurement datum of the period between organ resection and the time of first clamping perfomed in vivo."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "in vivo intraoperative ischemic period"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000132
    obo:IAO_0000115 "A data item on the duration of blood pressure variances of greater than 20 mmHg from a patient's pre-operative baseline from the time of anesthesia induction to 15 minutes post."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "BP excursions from time of anesthesia induction to 15 minutes post"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "vital sign blood pressure variance early in organ excision"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000133
    obo:IAO_0000115 "A data item on the duration of blood pressure variances of greater than 20 mmHg from a patient's pre-operative baseline from 15 minutes post anesthesia induction to the organ excision."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "BP excursions from 15 minutes post anesthesia induction to organ excision"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "vital sign blood pressure variance late in organ excision"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000134
    obo:IAO_0000115 "A time stamped measurement datum that is the first temperature recorded in the operating room of the specimen donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "first temperature recorded in operating room of specimen donor"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000582 .

obo:OBIB_0000135
    obo:IAO_0000115 "A  time stamped measurement datum that is the second temperature recorded in the operating room of the specimen donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "second temperature recorded in operating room of specimen donor"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000582 .

obo:OBIB_0000136
    obo:IAO_0000115 "A comment from tissue procurement of the epochs of oxygen desaturation of less than 92% for more than 5 minutes prior to organ excision."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "oxygen desaturation epochs prior to organ excision description"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000137
    obo:IAO_0000115 "A measurement datum of the level of carbon dioxide gas at time closest to organ exiscion from the specimen donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "carbon dioxide level of specimen donor recorded at time closest to organ excision"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000138
    obo:IAO_0000115 "A measurement datum of the volume of albumin administered during surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "albumin volume administered intraoperatively"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000139
    obo:IAO_0000115 "A count of the number of units of packed red blood cells administered during surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "amount of packed red blood cells administered intraoperatively"^^xsd:string ;
    rdfs:subClassOf obo:APOLLO_SV_00000032 .

obo:OBIB_0000140
    obo:IAO_0000115 "A measurement datum of the volume of platelets administered during surgery measured."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "platelet volume administered intraoperatively"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000141
    obo:IAO_0000115 "A count of the number of units of fresh frozen plasma administered during surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "amount of fresh frozen plasma administered intraoperatively"^^xsd:string ;
    rdfs:subClassOf obo:APOLLO_SV_00000032 .

obo:OBIB_0000142
    obo:IAO_0000115 "A measurement datum of the volume of intraoperative blood loss from the specimen donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "intraoperative blood loss of specimen donor"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor intraoperative blood loss volume measurement datum"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000143
    obo:IAO_0000115 "A specimen donor intraoperative blood loss volume measurement datum obtained prior to organ excision."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "intraoperative blood loss of specimen donor prior to organ excision"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor intraoperative blood loss prior to organ excision volume measurement datum"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000142 .

obo:OBIB_0000144
    obo:IAO_0000115 "A specimen donor intraoperative blood loss volume measurement datum obtained at the end of surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "intraoperative blood loss of specimen donor at end of surgery"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor intraoperative blood loss at end of surgery volume measurement datum"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000142 .

obo:OBIB_0000145
    obo:IAO_0000115 "A measurement datum of the volume of intraoperative urine excreted obtained from the specimen donor during surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "intraoperative urine volume excreted"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor intraoperative urine excreted volume measurement datum"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000146
    obo:IAO_0000115 "A specimen donor intraoperative urine excreted volume measurement datum obtained during prior to organ excision."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "intraoperative urine volume excreted of specimen donor prior to organ excision"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor intraoperative urine excreted prior to organ excision volume measurement datum"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000145 .

obo:OBIB_0000147
    obo:IAO_0000115 "A specimen donor intraoperative urine excreted volume measurement datum obtained at the end of surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "intraoperative urine volume excreted of specimen donor at end of surgery"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor intraoperative urine excreted at end of surgery volume measurement datum"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000145 .

obo:OBIB_0000148
    obo:IAO_0000115 "An information content entity that is an indication of whether ascites fluid was collected from the specimen donor during organ excision."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indicator of ascites fluid collection during surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000149
    obo:IAO_0000115 "A measurement datum of the volume of ascites fluid collected from the specimen donor during surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "ascites fluid from specimen donor during surgery volume measurement datum"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000150
    obo:IAO_0000115 "A time measurement datum of the duration of fasting by the specimen donor prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "Duration of fasting by specimen donor prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000151
    obo:IAO_0000115 "A comment from tissue procurement of the pre-operative bowel preparation performed prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on donor pre-operative bowel preparation prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000152
    obo:IAO_0000115 "A comment from tissue procurement of notable events that occurred during surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on notable events during donor surgery"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000153
    obo:IAO_0000115 "A data item indicating the time at which the surgical specimen left the operating for delivery to the pathology gross room."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time specimen left operating room"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000154
    obo:IAO_0000115 "A surgical procedure with the removal of the uterus, cervix, fallopian tubes, and ovaries. This is the most common surgery done for endometrial cancer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.webmd.com/cancer/cervical-cancer/hysterectomy-for-endometrial-cancer"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "hysterectomy with bilateral salpingo-oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000155
    obo:IAO_0000115 "A surgical procedure with the removal of the uterus, cervix, left fallopian tube, and left ovary."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "hysterectomy with left salpingo-oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000156
    obo:IAO_0000115 "A surgical procedure with the removal of the uterus, cervix, right fallopian tube, and right ovary."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "hysterectomy with right salpingo-oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000157
    obo:IAO_0000115 "A surgical procedure with the removal of both ovaries."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.mayoclinic.org/tests-procedures/oophorectomy/home/ovc-20314905"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "bilateral oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000158
    obo:IAO_0000115 "A surgical procedure with the removal of the left ovary."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000159
    obo:IAO_0000115 "A surgical procedure with the removal of the right ovary."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000160
    obo:IAO_0000115 "A surgical procedure that removes all organs from a person's pelvic cavity including the urinary bladder, urethra, rectum, and anus."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Pelvic_exenteration"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "pelvic exenteration"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000161
    obo:IAO_0000115 "A surgical procedure to remove a mass (growth or tumor) on the ovary or in the pelvis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://innovativegyn.com/conditions/ovarian-cyst-and-pelvic-mass/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "pelvic mass excision"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000162
    obo:IAO_0000115 "A surgical procedure to remove both ovaries and both fallopian tubes."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://www.cancer.gov/publications/dictionaries/cancer-terms?cdrid=322852"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "bilateral salpingo-oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000163
    obo:IAO_0000115 "A surgical procedure to remove the left ovary and left fallopian tube."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left salpingo-oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000164
    obo:IAO_0000115 "A surgical procedure to remove the right ovary and right fallopian tube."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right salpingo-oophorectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000165
    obo:IAO_0000115 "A protocol providing the action or system by which the surgical procedure is to be performed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert,  Jie Zheng"^^xsd:string, "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "surgical method"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000166
    obo:IAO_0000115 "A surgical method in which operations are performed through the abdomen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "abdominal surgical method"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000165 .

obo:OBIB_0000167
    obo:IAO_0000115 "A surgical method in which operations are performed through the vagina."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "vaginal surgical method"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000165 .

obo:OBIB_0000168
    obo:IAO_0000115 "A surgical method in which operations are performed far from their location through small incisions (usually 0.5���1.5��cm) elsewhere in the body."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Laparoscopic_surgery"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "laparoscopic surgical method"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000165 .

obo:OBIB_0000169
    obo:IAO_0000112 "Laparoscopically Assisted Vaginal Hysterectomy (LAVH)"^^xsd:string ;
    obo:IAO_0000115 "A surgical method in which operations are performed through the vagina aided by laparoscopic tools and techniques."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "laparoscopically assisted vaginal surgical method"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000165 .

obo:OBIB_0000170
    obo:IAO_0000115 "A surgical procedure in which the body of the uterus is removed but the cervix is kept intact, as compared to the more common total hysterectomy, in which the uterus, cervix and fundus (the part of the uterus above the fallopian tube openings) are removed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://www.floridahospital.com/supracervical-hysterectomy"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "supracervical hysterectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000171
    obo:IAO_0000115 "A surgical method using very small tools attached to a robotic arm. The surgeon controls the robotic arm with a computer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://medlineplus.gov/ency/article/007339.htm"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "robotic surgical method"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000165 .

obo:OBIB_0000172
    obo:IAO_0000115 "An information content entity that is an indication of whether pelvic washings were collected during ovarian surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indicator of pelvic washings collected during ovarian surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000173
    obo:IAO_0000115 "A biopsy of the left kidney."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Kidney biopsy (left)"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left kidney biopsy"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002650 .

obo:OBIB_0000174
    obo:IAO_0000115 "A biopsy of the right kidney."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Kidney biopsy (right)"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right kidney biopsy"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002650 .

obo:OBIB_0000175
    obo:IAO_0000115 "A surgical procedure to remove a mass (growth or tumor) in the left kidney."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Kidney mass excision (left)"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left kidney mass excision"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000176
    obo:IAO_0000115 "A surgical procedure to remove part of the left kidney."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Nephrectomy (partial left)"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left partial nephrectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000177
    obo:IAO_0000115 "A surgical procedure to remove the entire left kidney."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Nephrectomy (radical left)"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left radical nephrectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000178
    obo:IAO_0000115 "A surgical procedure that is minimally invasive to remove a patient's left renal pelvis, kidney, ureter, and bladder cuff."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Nephroureterectomy (left)"^^xsd:string ;
    obo:IAO_0000119 "https://my.clevelandclinic.org/health/articles/nephroureterectomy"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left nephroureterectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000179
    obo:IAO_0000115 "A surgical procedure to remove a mass (growth or tumor) in the right kidney."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Kidney mass excision (right)"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right kidney mass excision"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000180
    obo:IAO_0000115 "A surgical procedure to remove part of the right kidney."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Nephrectomy (partial right)"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right partial nephrectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000181
    obo:IAO_0000115 "A surgical procedure to remove the entire right kidney."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Nephrectomy (radical right)"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right radical nephrectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000182
    obo:IAO_0000115 "A surgical procedure that is minimally invasive to remove a patient's right renal pelvis, kidney, ureter, and bladder cuff."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Nephroureterectomy (right)"^^xsd:string ;
    obo:IAO_0000119 "https://my.clevelandclinic.org/health/articles/nephroureterectomy"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right nephroureterectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000183
    obo:IAO_0000115 "A surgical method in which an incision is made using a scalpel. Open surgery is the traditional type of surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "open surgery"^^xsd:string ;
    obo:IAO_0000119 "https://www.verywell.com/open-surgery-3157124"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "open surgical method"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000165 .

obo:OBIB_0000184
    obo:IAO_0000115 "A biopsy of the left lung."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left lung biopsy"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002650 .

obo:OBIB_0000185
    obo:IAO_0000115 "A biopsy of the right lung."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right lung biopsy"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002650 .

obo:OBIB_0000186
    obo:IAO_0000115 "A surgical procedure to remove one of the lobes of the left lung."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.hopkinsmedicine.org/healthlibrary/test_procedures/pulmonary/lobectomy_92,P07749/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left lung lobectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000187
    obo:IAO_0000115 "A surgical procedure to remove one of the lobes of the right lung."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.hopkinsmedicine.org/healthlibrary/test_procedures/pulmonary/lobectomy_92,P07749/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right lung lobectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000188
    obo:IAO_0000115 "A surgical procedure to remove a mass (growth or tumor) in the left lung."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left lung mass excision"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000189
    obo:IAO_0000115 "A surgical procedure to remove a mass (growth or tumor) in the right lung."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right lung mass excision"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000190
    obo:IAO_0000115 "A surgical procedure performed to remove an entire left lung"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.cancercenter.com/treatments/pneumonectomy/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "left pneumonectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000191
    obo:IAO_0000115 "A surgical procedure performed to remove an entire right lung"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.cancercenter.com/treatments/pneumonectomy/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "right pneumonectomy"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000192
    obo:IAO_0000115 "A surgical procedure to remove a triangle-shaped slice of tissue from the left lung. It may be used to remove a tumor or some other type of tissue that requires removal and typically includes a small amount of normal tissue around it."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Wedge_resection"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "wedge resection of left lung"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000193
    obo:IAO_0000115 "A surgical procedure to remove a triangle-shaped slice of tissue from the right lung. It may be used to remove a tumor or some other type of tissue that requires removal and typically includes a small amount of normal tissue around it."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Wedge_resection"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "wedge resection of right lung"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000716 .

obo:OBIB_0000194
    obo:IAO_0000115 "An information content entity that is an indicator of whether pre-operative/pre-anesthesia blood samples were collected from the participant and were successfully banked in a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indicator of collected and banked pre-operative blood specimens"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000195
    obo:IAO_0000112 "The reason(s) that the pre-operative/pre-anesthesia blood samples were not received in the tissue bank as per the BPV Collection and Processing SOP."^^xsd:string ;
    obo:IAO_0000115 "A comment from tissue procurement providing a reason that the pre-operative/pre-anesthesia blood samples were not received in a biobank as per SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "reason for not banking pre-operative blood specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000196
    obo:IAO_0000115 "A reason for not banking pre-operative blood specimen which is the blood specimen was not received in the biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood not received in biobank"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000195 .

obo:OBIB_0000197
    obo:IAO_0000115 "A reason for not banking pre-operative blood specimen which is a minimum amount of required pre-op blood was not drawn."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "minimum amount of required pre-op blood not drawn"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000195 .

obo:OBIB_0000198
    obo:IAO_0000115 "A reason for not banking pre-operative blood specimen which is a minimum number of aliquots was not banked."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "minimum number of aliquots not banked"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000195 .

obo:OBIB_0000199
    obo:IAO_0000115 "A reason for not banking pre-operative blood specimen which is the blood was hemolyzed or not useable."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood was hemolyzed or not useable"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000195 .

obo:OBIB_0000200
    obo:IAO_0000112 "BPV SOP governing receipt and dissection of surgical tissue in the Tissue Bank"^^xsd:string ;
    obo:IAO_0000115 "A standard operating procedure for the receipt and dissection of surgical tissue in a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "receipt and dissection of surgical specimen SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000201
    obo:IAO_0000112 "Date and time tissue specimens were received in Tissue Bank from the Pathology Gross Room"^^xsd:string ;
    obo:IAO_0000115 "A data item indicating the date and time at which the specimen was received in the biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "data and time of biobank receipt of specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000202
    obo:IAO_0000115 "A personal name that designates the person who received a specimen in the biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of biobank person receiving specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000203
    obo:IAO_0000115 "A textual entity that states a comment or issue regarding specimen receipt or deviations from a standard operating procedure for specimen receipt."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment from specimen receipt"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000204
    obo:IAO_0000112 "Parent Tissue Specimen ID of required study tumor tissue received in Tissue Bank from the Pathology Gross Room"^^xsd:string ;
    obo:IAO_0000115 "A specimen ID denoting a specimen that is used to create a specimen family."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "parent specimen ID"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000721 .

obo:OBIB_0000205
    obo:IAO_0000115 "A personal name that designates the person who performed the dissection of a surgical specimen to create a specimen family."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of dissector of parent specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000206
    obo:IAO_0000115 "A data item indicating the time that the dissection of a specimen for specimen family creation began."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "beginning time of parent specimen dissection."^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000207
    obo:IAO_0000115 "A data item indicating the time that the dissection of a specimen for specimen family creation ended."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "ending time of parent specimen dissection."^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000208
    obo:IAO_0000112 "The gross appearance of the parent sample as determined in the pathology gross room."^^xsd:string ;
    obo:IAO_0000115 "A data item on manifestations of disease produced from macroscopic analysis of a specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Gross_pathology"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen gross appearance"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000209
    obo:IAO_0000115 "A specimen gross appearance of a tumor manifestation."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen gross appearance of tumor"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000208 .

obo:OBIB_0000210
    obo:IAO_0000115 "A biopsy that uses a thin, hollow needle to draw cells from a body."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "needle biopsy"^^xsd:string ;
    obo:IAO_0000119 "http://www.mayoclinic.org/tests-procedures/needle-biopsy/basics/what-you-can-expect/prc-20012926"^^xsd:string ;
    obo:IAO_0000231 obo:IAO_0000228 ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0100001 obo:OBI_0002655 ;
    a owl:Class ;
    rdfs:label "obsolete fine needle biopsy"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OBIB_0000211
    obo:IAO_0000115 "A biopsy that uses a hollow tube that allows extracting a core of tissue for testing. This type of needle biopsy uses a wider needle than does fine-needle aspiration."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "core biopsy"^^xsd:string ;
    obo:IAO_0000119 "http://www.mayoclinic.org/tests-procedures/needle-biopsy/basics/what-you-can-expect/prc-20012926"^^xsd:string ;
    obo:IAO_0000231 obo:IAO_0000228 ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0100001 obo:OBI_0002656 ;
    a owl:Class ;
    rdfs:label "obsolete core needle biopsy"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OBIB_0000212
    obo:IAO_0000115 "A processed material that is a non-carcinogenic, non-cross-linking mixture of different alcohols, acid and a soluble organic compound that rapidly preserves morphology and all bio-molecules."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "PAXgene Tissue FIX"^^xsd:string ;
    obo:IAO_0000119 "http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027704"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "PAXgene fixation reagent"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:OBIB_0000213
    obo:IAO_0000112 "10% neutral buffered formalin (4% neutral buffered formaldehyde)"^^xsd:string ;
    obo:IAO_0000115 "A processed material that is a mixture of formalin (formaldehyde), phosphates, and water used as a standard fixative for diagnostic preparations."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "buffered formalin"^^xsd:string ;
    obo:IAO_0000119 "http://stainsfile.info/StainsFile/prepare/fix/fixatives/formalin-buffered.htm"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "neutral buffered formalin"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:OBIB_0000214
    obo:IAO_0000115 "A protocol specifying the buffer formula of the fixative in which tissue specimens are processed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Fixative formula (buffer)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "buffer formula for specimen fixative"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000215
    obo:IAO_0000115 "A data item that indicates the the date determined by appropriate stability testing of the medical product, lot, batch or item after which the product may not meet the appropriate regulatory agencies requirements."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "medical product expiration date"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000216
    obo:IAO_0000115 "A manufacturer that produces fixatives used in specimen collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "fixative product manufacturer"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000835 .

obo:OBIB_0000217
    obo:IAO_0000115 "A manufacturer that produces materials to be sold for profit."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "commercial source"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "commercial manufacturer"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000835 .

obo:OBIB_0000218
    obo:IAO_0000115 "A manufacturer that produces materials internally for the internal needs of the organization."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "In-house source"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "in-house manufacturer"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000835 .

obo:OBIB_0000219
    obo:IAO_0000115 "A buffered formalin condition by virtue of the formalin having undergone a recycling process such as fractional distillation by temperature."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "recycled formalin"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "recycled buffered formalin condition"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000220 .

obo:OBIB_0000220
    obo:IAO_0000115 "A quality that inheres in buffered formalin by virtue of its usage and processing."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "buffered formalin condition"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000019 .

obo:OBIB_0000221
    obo:IAO_0000115 "A buffered formalin condition by virtue of being newly prepared with formalin that has not been previously used."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "fresh formalin"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "fresh buffered formalin condition"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000220 .

obo:OBIB_0000222
    obo:IAO_0000115 "A standard operating procedure for collection and processing of blood specimens."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood specimen collection and processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000223
    obo:IAO_0000115 "An information content entity indicating whether the minimum requirement according to a standard operating procedure was met for pre-operative blood collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "minimum required pre-operative blood tubes collected"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000224
    obo:IAO_0000115 "An information content entity indicating whether approval was received to proceed with collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "approval to proceed with collection"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000225
    obo:IAO_0000115 "A health care provider role borne by a person trained to draw blood from a patient for clinical or medical testing, transfusions, donations, or research. Phlebotomists collect blood primarily by performing venipunctures."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Phlebotomy"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "phlebotomist role"^^xsd:string ;
    rdfs:subClassOf obo:OMRSE_00000012 .

obo:OBIB_0000226
    obo:IAO_0000115 "A health care provider role borne by a medical practitioner trained in anesthesia and perioperative medicine."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Anesthesiologist"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "anesthesiologist role"^^xsd:string ;
    rdfs:subClassOf obo:OMRSE_00000012 .

obo:OBIB_0000227
    obo:IAO_0000115 "A nurse role borne by a nurse who specializes in the administration of anesthesia."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Nurse_anesthetist"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "nurse anesthetist role"^^xsd:string ;
    rdfs:subClassOf obo:OMRSE_00000014 .

obo:OBIB_0000228
    obo:IAO_0000115 "A health care provider role borne by a person whose duties are to prepare operating rooms, set up equipment and surgical tools, and assist doctors and nurses during surgeries as instructed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "O.R. technician"^^xsd:string, "surgical technician"^^xsd:string ;
    obo:IAO_0000119 "http://work.chron.com/become-operating-room-technician-12460.html"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "operating room technician"^^xsd:string ;
    rdfs:subClassOf obo:OMRSE_00000012 .

obo:OBIB_0000229
    obo:IAO_0000115 "A data item indicating the date and time when a blood specimen was collected."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Date and Time Blood Was Drawn"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time of blood collection"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000230
    obo:IAO_0000115 "A blood specimen collection that occurs pre-operatively or pre-anesthesia relative to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "pre-operative blood draw"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "pre-operative blood specimen collection"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000231 .

obo:OBIB_0000231
    obo:IAO_0000115 "A collecting specimen from organism that results in a blood specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "blood draw"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood specimen collection"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0600005 .

obo:OBIB_0000232
    obo:IAO_0000115 "A personal name that designates the person who performed the collection of a blood specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person performing blood draw"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000233
    obo:IAO_0000115 "A specimen container for collecting blood and has ethylenediaminetetraacetic acid (EDTA) as an anticoagulant."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "lavender top tube"^^xsd:string ;
    obo:IAO_0000119 "http://www.mayomedicallaboratories.com/customer-service/faq/specimen/collection-tubes"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood specimen container with EDTA"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002088 .

obo:OBIB_0000234
    obo:IAO_0000115 "A specimen container developed by PreAnalytiX that is intended to collect, anticoagulate, stabilize, transport, and store a venous whole blood sample for preparation of high quality DNA for use with molecular diagnostic test methods that require DNA."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.preanalytix.com/sites/default/files/handbooks/PAXgene%20Blood%20DNA%20Tube%20IVD%20Product%20Circular.pdf"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "PAXgene DNA vacutainer"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002088 .

obo:OBIB_0000235
    obo:IAO_0000115 "A specimen container developed by PreAnalytiX that contains a proprietary reagent for stabilization of intracellular RNA immediately upon collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.preanalytix.com/products/blood/RNA/paxgene-blood-rna-tube"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "PAXgene RNA vacutainer"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002088 .

obo:OBIB_0000236
    obo:IAO_0000112 "Volume of blood collected in milliliters"^^xsd:string ;
    obo:IAO_0000115 "A scalar measurement datum that is the output of a volume measurement assay that has a blood specimen as evaluant."^^xsd:string ;
    obo:IAO_0000116 "need volume measurement assay from OBI first"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood specimen volume"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000237
    obo:IAO_0000115 "A blood specimen collection that is performed with a fresh needle inserted into a vein."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "fresh venous needle stick"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "fresh venous needle blood specimen collection"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000231 .

obo:OBIB_0000238
    obo:IAO_0000115 "A textual entity that states additional information about the blood specimen or donor that is deemed relevant for the specimen collection process."^^xsd:string ;
    obo:IAO_0000116 "Consider generalizing label of ���comment from tissue procurement��"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment from blood specimen collection"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000239
    obo:IAO_0000115 "A data item indicating the date and time at which the specimen was received in the laboratory for processing."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "data and time of laboratory receipt of specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000240
    obo:IAO_0000115 "A personal name that designates the person who received a blood specimen in the laboratory."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person receiving blood specimen in laboratory"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000241
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay occurring in a laboratory and performed when a blood specimen is received."^^xsd:string ;
    obo:IAO_0000116 "need temperature measurement assay from OBI and humidity from PATO"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "temperature in lab when blood specimen was received"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000242
    obo:IAO_0000115 "A measurement datum that is the output of an assay of humidity occurring in a laboratory and performed when a blood specimen is received."^^xsd:string ;
    obo:IAO_0000116 "need humidity from PATO"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "humidity in lab when blood specimen was received"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000243
    obo:IAO_0000112 "DNA PAXgene tube Specimen Barcode ID"^^xsd:string ;
    obo:IAO_0000115 "A specimen barcode that is associated with a vacutainer."^^xsd:string ;
    obo:IAO_0000116 "need specimen barcode"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "vacutainer specimen barcode"^^xsd:string ;
    rdfs:subClassOf obo:FLU_0001019 .

obo:OBIB_0000244
    obo:IAO_0000112 "Time DNA PAXgene tube was frozen at -20�_C �� 2�_C"^^xsd:string ;
    obo:IAO_0000115 "A time of specimen freezing which occurred at approximately -20�_C."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of specimen freezing at approximately -20 degrees C"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000724 .

obo:OBIB_0000245
    obo:IAO_0000112 "Time DNA PAXgene tube was transferred to storage at -75�_C �� 5�_C"^^xsd:string ;
    obo:IAO_0000115 "A time of specimen freezing which occurred at -75�_ �� 5�_C."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of specimen freezing at -70 to -80 degrees C"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000724 .

obo:OBIB_0000246
    obo:IAO_0000115 "A personal name that designates the person who stored a specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person storing specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000247
    obo:IAO_0000112 "DNA PAXgene tube was collected and stored in accordance with the specified SOP"^^xsd:string ;
    obo:IAO_0000115 "An information content entity indicating whether the specimen was collected and stored in accordance with the specified SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen was collected and stored in accordance with the specified SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000248
    obo:IAO_0000112 "DNA PAXgene tube storage comments"^^xsd:string ;
    obo:IAO_0000115 "A textual entity that states additional information about the blood specimen or donor that is deemed relevant for the specimen storage process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment from blood specimen storage"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000249
    obo:IAO_0000112 "Time plasma processing began."^^xsd:string ;
    obo:IAO_0000115 "A data item indicating the time when a blood specimen was processed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of blood processing"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000250
    obo:IAO_0000115 "An identifier that specifically identifies a particular conical centrifuge tube."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Conical centrifuge Tube code"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "conical centrifuge tube identifier"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000251
    obo:IAO_0000115 "A blood specimen volume of blood contained in a conical centrifuge tube."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood specimen volume in conical centrifuge tube"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000236 .

obo:OBIB_0000252
    obo:IAO_0000115 "A specimen barcode that is associated with a blood plasma specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood plasma specimen barcode"^^xsd:string ;
    rdfs:subClassOf obo:FLU_0001019 .

obo:OBIB_0000253
    obo:IAO_0000115 "A scalar measurement datum that is the output of a volume measurement assay that has a blood plasma specimen as evaluant."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "blood plasma specimen volume"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000254
    obo:IAO_0000115 "A data item indicating the time when a blood plasma specimen was placed on dry ice."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of blood plasma specimen placement on dry ice"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000255
    obo:IAO_0000115 "A specimen barcode that is associated with a cryovial."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "cryovial specimen barcode"^^xsd:string ;
    rdfs:subClassOf obo:FLU_0001019 .

obo:OBIB_0000256
    obo:IAO_0000115 "A data item indicating the time when a blood plasma specimen was transferred to a freezer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of blood plasma specimen transfer to freezer"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000257
    obo:IAO_0000115 "A personal name that designates the person who processed a blood specimen to generate aliquots of blood plasma specimens."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person processing blood plasma specimen aliquots"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000258
    obo:IAO_0000115 "A personal name that designates the person who transferred blood plasma specimens to freezer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person transferring blood plasma specimens to freezer"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000259
    obo:IAO_0000112 "Plasma Processing Was Performed in Accordance With Specified SOP"^^xsd:string ;
    obo:IAO_0000115 "An information content entity indicating whether the specimen was processed in accordance with the specified SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen was processed in accordance with the specified SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000260
    obo:IAO_0000112 "Plasma Processing Comments"^^xsd:string ;
    obo:IAO_0000115 "A textual entity that states additional information about the blood specimen or donor that is deemed relevant for specimen processing."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment from blood specimen processing"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000261
    obo:IAO_0000115 "An information content entity indicating whether the presence of gross hemolysis of plasma was observed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "presence of gross hemolysis of plasma observed"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000262
    obo:IAO_0000112 "Volume in ml of Whole Cell Pellet"^^xsd:string ;
    obo:IAO_0000115 "A scalar measurement datum that is the output of a volume measurement assay that has a cell pellet as evaluant."^^xsd:string ;
    obo:IAO_0000116 "need volume measurement assay from OBI first"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "cell pellet volume"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000263
    obo:IAO_0000112 "Whole Cell Pellet Aliquot Specimen Barcode ID"^^xsd:string ;
    obo:IAO_0000115 "A specimen barcode that is associated with a cell pellet specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "cell pellet specimen barcode"^^xsd:string ;
    rdfs:subClassOf obo:FLU_0001019 .

obo:OBIB_0000264
    obo:IAO_0000115 "A data item indicating the time when processing of a blood cell pellet specimen was completed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of completion of blood cell pellet processing"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000265
    obo:IAO_0000115 "A data item indicating the time when the blood cell pellet specimen was transferred to storage."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of blood cell pellet transfer to storage"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000266
    obo:IAO_0000115 "A personal name that designates the person who performed processing of the blood cell pellet specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person processing blood cell pellet specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000267
    obo:IAO_0000115 "A data item indicating the calendar date when a specimen was placed on dry ice for transport."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of specimen placement on dry ice for transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000268
    obo:IAO_0000115 "A data item indicating the time when a specimen was placed on dry ice for transport."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of specimen placement on dry ice for transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000269
    obo:IAO_0000115 "A data item indicating the calendar date when a specimen was stored at -75_ � 5_C."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of specimen freezing at -70 to -80 degrees C"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000270
    obo:IAO_0000115 "A data item indicating the calendar date when a specimen was transported to another institution."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "date of specimen shipment"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of specimen transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000271
    obo:IAO_0000115 "A data item indicating the time when a specimen was transported to another institution."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "time of specimen shipment"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of specimen transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000272
    obo:IAO_0000115 "A role borne by an organization that is the provider of a specimen that is transported to another organization."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "specimen shipping organization"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen transporting organization"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000273
    obo:IAO_0000115 "A role borne by an organization that is the recipient of a specimen that is transported from another organization."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen receiving organization"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000274
    obo:IAO_0000115 "A personal name that designates the person who is responsible for the transport of a specimen to another organization."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "name of person responsible for specimen shipment"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person responsible for specimen transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000275
    obo:IAO_0000115 "A personal name that designates the person who verified the specimen transport was according to best practice, international standards, and industry regulations as trained by the IATA."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "name of IATA-trained person verifying specimen shipment"^^xsd:string ;
    obo:IAO_0000119 "http://www.iata.org/training/pages/index.aspx"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of IATA-trained person verifying specimen transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000276
    obo:IAO_0000115 "A data item indicating the calendar date when a specimen was received after transport from another institution."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "date of receiving specimen shipment"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of receiving specimen transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000277
    obo:IAO_0000115 "A data item indicating the time when a specimen was received after transport from another institution."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "time of receiving specimen shipment"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of receiving specimen transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000278
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay performed on a collection packet when it is received with a specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "temperature of interior kit at time of receipt"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "temperature of specimen collection packet at time of receipt"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000279
    obo:IAO_0000115 "A personal name that designates the person who received the specimen that was transported from another organization."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person receiving specimen shipment"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000280
    obo:IAO_0000115 "An information content entity indicating that the physical condition of a specimen upon receipt after transport was good."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen shipment received in good condition"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000281
    obo:IAO_0000115 "An information content entity indicating that the physical condition of a specimen upon receipt after transport was poor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen shipment received in poor condition"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000282
    obo:IAO_0000115 "A textual entity that states information about the physical integrity or wholeness of the specimen that is deemed relevant for the specimen transport process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on specimen integrity after transport"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000283
    obo:IAO_0000115 "A data item indicating the calendar date when a specimen arrives in the gross pathology room for processing and review."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of specimen receipt for pathologist processing"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000284
    obo:IAO_0000115 "A data item indicating the time when a specimen arrives in the gross pathology room for processing and review."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of receipt for pathologist processing"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000285
    obo:IAO_0000115 "A personal name that designates the person who performed a quality control inspection of the specimen that is to be transported to another organization."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of quality control inspector of specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000286
    obo:IAO_0000115 "A personal name that designates the person who performed the data entry process for filling in a tissue recovery case report form."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of data entry person for tissue recovery form"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000287
    obo:IAO_0000115 "A personal name that designates the person who is the leader of the team responsible for entering the tissue recovery form data."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of team leader for filling out tissue recovery form"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000288
    obo:IAO_0000115 "A standard operating procedure for fixation of a tissue to the state where it is completely infiltrated with a suitable histological wax and can be embedded ready for section cutting on the microtome for a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "http://www.leicabiosystems.com/pathologyleaders/an-introduction-to-specimen-processing/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000289
    obo:IAO_0000115 "An information content entity that indicates whether equipment was maintained following the manufacturers recommendations."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "equipment maintained as per manufacturer recommendations"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000290
    obo:IAO_0000115 "A textual entity that states information about maintenance discrepancies from manufacturer recommendations."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on maintenance discrepancy from manufacturer recommendations"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000291
    obo:IAO_0000115 "A role borne by a chemical that is realized in the formalin-fixed paraffin-embedded (FFPE) processes to remove alcohol used for specimen dehydration, remove stains, and prepare a specimen for infiltration medium."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE clearing agent role"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000292
    obo:IAO_0000115 "An information content entity that indicates whether duration of the alcohol stage followed that prescribed in the FFPE tissue processing SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence of alcohol stage duration to FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000293
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the duration of the alcohol stage in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE alcohol stage duration"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000294
    obo:IAO_0000115 "An information content entity that indicates whether duration of the dehydration process followed that prescribed in the FFPE tissue processing SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence of dehydration process duration to FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000295
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the duration of the dehydration process in the formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE dehydration process duration"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000296
    obo:IAO_0000115 "An information content entity that indicates whether temperature of the dehydration process followed that prescribed in the FFPE tissue processing SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence of dehydration process temperature to FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000297
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay performed on a specimen in alcohol during the dehydration process  in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE dehydration process temperature"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000298
    obo:IAO_0000115 "An information content entity that indicates whether the number of stages and replicates followed that prescribed in the FFPE tissue processing SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence of stage and replicate numbers to FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000299
    obo:IAO_0000115 "A data item that indicates the number of stages and replicates in a FFPE process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "number of FFPE stages/replicates"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000300
    obo:IAO_0000115 "An information content entity that indicates whether the duration in clearing agent followed that prescribed in the FFPE tissue processing SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence of duration in clearing agent to FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000301
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the duration in clearing agent in the formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE clearing agent duration"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000302
    obo:IAO_0000115 "An information content entity that indicates whether the temperature of clearing agent followed that prescribed in the FFPE tissue processing SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence of temperature of clearing agent to FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000303
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay performed on a specimen in clearing agent in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE clearing agent temperature"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000304
    obo:IAO_0000115 "An information content entity that indicates whether the paraffin impregnation method followed that prescribed in the FFPE tissue processing SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence to paraffin impregnation method in FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000305
    obo:IAO_0000115 "A protocol for the paraffin impregnation step of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE paraffin impregnation method"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000306
    obo:IAO_0000115 "An information content entity that indicates whether the paraffin temperature followed that prescribed in the FFPE tissue processing SOP."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence of paraffin temperature to FFPE tissue processing SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000307
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay performed on paraffin in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE paraffin temperature"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000308
    obo:IAO_0000115 "A textual entity that states information relevant to tissue processing in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on FFPE tissue processing"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000309
    obo:IAO_0000115 "A standard operating procedure for the paraffin embedding of a formalin-fixed paraffin-embedded (FFPE) tissue."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue paraffin embedding SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000310
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay performed during the paraffin processing for embedding in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE paraffin processing for embedding temperature"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000311
    obo:IAO_0000115 "A paraffin that has not been previously used or recycled."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "fresh paraffin"^^xsd:string ;
    rdfs:subClassOf obo:DRON_00015464 .

obo:OBIB_0000312
    obo:IAO_0000115 "A scalar measurement datum that is the output of an age measurement assay performed on paraffin."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "age of paraffin"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000313
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the total time that freshly poured blocks were cooled in the formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "total time FFPE freshly poured blocks were cooled"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000314
    obo:IAO_0000115 "A standard operating procedure for the handling, tracking, and storing of a formalin-fixed paraffin-embedded (FFPE) tissue block."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue block handling, tracking, and storage SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000315
    obo:IAO_0000115 "An information content entity that indicates whether the FFPE tissue block storage SOP was followed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "adherence to FFPE tissue block storage SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000316
    obo:IAO_0000112 "discrepancies from a FFPE tissue block storage SOP."^^xsd:string ;
    obo:IAO_0000115 "A textual entity that states information relevant to storage of a formalin-fixed paraffin-embedded (FFPE) tissue block."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on FFPE tissue block storage"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000317
    obo:IAO_0000115 "A textual entity that states information relevant to paraffin embedding of a formalin-fixed paraffin-embedded (FFPE) tissue."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on paraffin embedding of FFPE tissue"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000318
    obo:IAO_0000115 "A personal name that designates the person who performed a specimen slide preparation."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Slide Prep Technician Name"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of specimen slide preparation technician"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000319
    obo:IAO_0000115 "A standard operating procedure for the preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue section preparation SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000320
    obo:IAO_0000115 "An age that inheres in a microtome blade."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "microtome blade age"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000011 .

obo:OBIB_0000321
    obo:IAO_0000115 "A microtome blade age that indicates that the microtome blade is as new as possible."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "fresh microtome blade"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000320 .

obo:OBIB_0000322
    obo:IAO_0000115 "A protocol describing the preparation on the faced block prior to sectioning of a formalin-fixed paraffin-embedded (FFPE) tissue."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "preparation of FFPE block face for sectioning protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000323
    obo:IAO_0000115 "A textual entity that describes the carge on a glass slide."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Slide Charge"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "description of glass slide charge"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000324
    obo:IAO_0000115 "An information content entity that indicates that a glass slide has been positively charged."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "charged slide"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "charged glass slide indicator"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000325
    obo:IAO_0000115 "An information content entity that indicates that a glass slide has not been positively charged."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "uncharged slide"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "uncharged glass slide indicator"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000326
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay performed on a water bath used in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE water bath temperature"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000327
    obo:IAO_0000115 "An information content entity that indicates the frequency with which microtome maintenance is performed and recorded."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "microtome maintenance frequency"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000328
    obo:IAO_0000115 "A microtome maintenance frequency that indicates that microtome maintenance is performed and recorded daily."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "daily microtome maintenance"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000327 .

obo:OBIB_0000329
    obo:IAO_0000115 "A textual entity that states information about deviations from a microtome daily maintenance standard operating procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on deviations from microtome daily maintenance SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000330
    obo:IAO_0000115 "An information content entity that indicates the frequency with which water bath maintenance is performed and recorded."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "water bath maintenance frequency"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000331
    obo:IAO_0000115 "A water bath maintenance frequency that indicates that microtome maintenance is performed and recorded daily."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "daily water bath maintenance"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000330 .

obo:OBIB_0000332
    obo:IAO_0000115 "A textual entity that states information about deviations from a water bath daily maintenance standard operating procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on deviations from water bath daily maintenance SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000333
    obo:IAO_0000115 "A textual entity that states information relevant to preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on preparation of FFPE tissue section"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000334
    obo:IAO_0000115 "A standard operating procedure for the hematoxylin and eosin (H&E) staining and slide mounting of a formalin-fixed paraffin-embedded (FFPE) tissue section."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue section H&E staining and mounting SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000070 .

obo:OBIB_0000335
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the duration in an oven for the hematoxylin and eosin staining of a formalin-fixed paraffin-embedded (FFPE) tissue section."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue section H&E staining in oven duration"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000336
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay performed on a oven during a formalin-fixed paraffin-embedded (FFPE) tissue section hematoxylin and eosin (H&E) staining."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "oven temperature during FFPE tissue section H&E staining"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000337
    obo:IAO_0000115 "A protocol describing the deparaffinization method used during the hematoxylin and eosin (H&E) stained slide preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "H&E deparaffinization method"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue section H&E deparaffinization protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000338
    obo:IAO_0000115 "A protocol describing the staining method used during the hematoxylin and eosin (H&E) stained slide preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "H&E staining method"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue section H&E staining protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000339
    obo:IAO_0000115 "A protocol describing the clearing method used during the hematoxylin and eosin (H&E) stained slide preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "H&E clearing method"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue section H&E clearing protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000340
    obo:IAO_0000115 "A protocol describing the method for applying a cover slip used during the hematoxylin and eosin (H&E) stained slide preparation of a formalin-fixed paraffin-embedded (FFPE) tissue section."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "H&E cover slipping method"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue section H&E cover slip protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000341
    obo:IAO_0000115 "A planned process involving the manual performance of the FFPE tissue section H&E deparaffinization protocol."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "manual FFPE tissue section H&E deparaffinization"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000342
    obo:IAO_0000115 "A planned process involving the manual performance of the FFPE tissue section H&E staining protocol."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "manual FFPE tissue section H&E staining"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000343
    obo:IAO_0000115 "A planned process involving the manual performance of the FFPE tissue section H&E clearing protocol."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "manual FFPE tissue section H&E clearing"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000344
    obo:IAO_0000115 "A planned process involving the manual performance of the FFPE tissue section H&E cover slip protocol."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "manual FFPE tissue section H&E cover slipping"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000345
    obo:IAO_0000115 "A textual entity that states information relevant to the preparation of a formalin-fixed paraffin-embedded (FFPE) hematoxylin and eosin (H&E) stained slide."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on preparation of FFPE H&E stained slide"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000346
    obo:IAO_0000115 "A data item that indicates the frequency with which hematoxylin and eosin (H&E) staining equipment maintenance is performed and recorded."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "H&E staining equipment maintenance performed and recorded frequency"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000347
    obo:IAO_0000115 "A categorical value specification that is used to record the frequency with which hematoxylin and eosin (H&E) staining equipment maintenance is performed and recorded. Categories include daily, weekly, bi-monthly, and per SOP."^^xsd:string ;
    obo:IAO_0000116 "Add instances: daily, weekly, bi-monthly, per SOP"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "H&E staining equipment maintenance performed and recorded frequency value specification"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBIB_0000348
    obo:IAO_0000115 "A textual entity that states information about deviations from a hemtoxylin and eosin (H&E) equipment maintenance standard operating procedure."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on deviations from H&E equipment maintenance SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000349
    obo:IAO_0000115 "A specimen barcode associated with the specific chart (key) used to randomly assign specimens to one of several distinct experimental protocols."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen randomization key ID"^^xsd:string ;
    rdfs:subClassOf obo:FLU_0001019 .

obo:OBIB_0000350
    obo:IAO_0000115 "A role borne by personnel responsible for managing human research protocol requirements including but not limited to screening, obtaining authorization, consenting and/or enrollment activities."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Consent or Research Analyst/Coordinator role"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "manager of human research protocol requirements role"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000351
    obo:IAO_0000115 "A textual entity that is a notification within a clinical data repository that a specimen donor was a transplant recipient."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "transplant alert associated with specimen donor"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000352
    obo:IAO_0000115 "A textual entity that is a notification within a clinical data repository that specimen donor serology results include positive infectious disease data."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "serology alert associated with specimen donor"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000353
    obo:IAO_0000115 "A data item indicating the date and time at which the parent specimen ID was recorded."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "data and time parent specimen ID was recorded"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000354
    obo:IAO_0000115 "A textual entity that states additional information deemed relevant for tissue specimen processing."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on tissue specimen processing"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000355
    obo:IAO_0000112 "Brain Endowment Bank at Miller School of Medicine, of the University of Miami."^^xsd:string ;
    obo:IAO_0000115 "A biobank that focuses on the special requirements of the human brain with regards to preservation, handling, and analysis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "brain bank"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "human brain biobank"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000616 .

obo:OBIB_0000356
    obo:IAO_0000115 "A biobank which receives its specimens primarily/exclusively from tissue source sites.� Activities include receipt, some processing, production of slides/images of the tissue, storage, and retrieval/shipping of materials on-demand."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Central Biospecimen Repository"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "central biobank"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000616 .

obo:OBIB_0000357
    obo:IAO_0000115 "A laboratory that specializes in acquiring human tissues and analyzing components such as DNA and RNA from them."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "LDACC"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "laboratory, data analysis, and coordinating center for human specimens"^^xsd:string ;
    rdfs:subClassOf <http://vivoweb.org/ontology/core#Laboratory> .

obo:OBIB_0000358
    obo:IAO_0000115 "A laboratory that performs a rigorous review of images of tissue specimens by a group of senior pathologists not involved in the specimen collection typically to evaluate and characterize the tissue (e.g., % necrosis)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "PRC"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "pathology research center"^^xsd:string ;
    rdfs:subClassOf <http://vivoweb.org/ontology/core#Laboratory> .

obo:OBIB_0000359
    obo:IAO_0000115 "A data item indicating the time when a specimen was placed in a container with stabilizing reagent."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time specimen place in stabilizer"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000360
    obo:IAO_0000115 "An identifier that specifically identifies a particular component of a collection packet."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "kit component ID"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "collection packet component ID"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000361
    obo:IAO_0000115 "A data item indicating the date and time at which a specimen was frozen by placement in liguid nitrogen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "data and time specimen was frozen in liquid nitrogen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000362
    obo:IAO_0000112 "weight of frozen tumor block after freezing in liquid nitrogen"^^xsd:string ;
    obo:IAO_0000115 "A mass measurement datum that is the result of measuring the weight of a frozen tissue specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "weight of frozen tissue specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000414 .

obo:OBIB_0000363
    obo:IAO_0000115 "A protocol for the fixation step of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE fixation protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000364
    obo:IAO_0000115 "A FFPE fixation protocol that specifies the planned delay to fixation time."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE fixation delay protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000363 .

obo:OBIB_0000365
    obo:IAO_0000115 "A specimen ID that specifically identifies a particular tissue cassete used in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE tissue cassette ID"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000721 .

obo:OBIB_0000366
    obo:IAO_0000115 "A data item indicating the date and time at which the FFPE tissue cassette ID was recorded."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "data and time FFPE tissue cassette ID was recorded"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000367
    obo:IAO_0000115 "A data item indicating the date and time when a tissue cassette was placed in fixative as part of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time FFPE tissue cassette placed in fixative"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000368
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the duration of the the planned delay of placing the tissue cassette in fixative in the formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "placement of tissue cassette in FFPE fixative delay duration"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000369
    obo:IAO_0000115 "A data item indicating the date and time when a tissue cassette was placed in a tissue processor as part of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time FFPE tissue cassette placed in processor"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000370
    obo:IAO_0000115 "A data item indicating the date and time when a tissue processor cycle ended as part of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time FFPE tissue processor cycle ended"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000371
    obo:IAO_0000115 "A time in fixative measurement that states the duration during which a specimen was submerged in fixative as part of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time in FFPE fixative measurement"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000060 .

obo:OBIB_0000372
    obo:IAO_0000115 "A data item indicating the date and time when a tissue cassette was removed from a tissue processor as part of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time FFPE tissue cassette removed from processor"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000373
    obo:IAO_0000115 "A data item indicating the date and time when a tissue embedding started as part of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time FFPE tissue embedding started"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000374
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the time between FFPE tissue processor cycle completion and embedding in a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "measurement of time between FFPE tissue processor cycle completion and embedding"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000375
    obo:IAO_0000115 "A data item indicating the date and time when a tissue cassette was frozen as part of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time FFPE tissue cassette was frozen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000376
    obo:IAO_0000115 "A protocol for the freezing step of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "FFPE freezing method"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE freezing protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000377
    obo:IAO_0000115 "A FFPE freezing protocol that involves the use of dry ice."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE freezing by dry ice protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000378
    obo:IAO_0000115 "A FFPE freezing protocol that involves the use of liquid nitrogen vapor phase."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE freezing by LN2 vapor phase protocol"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000272 .

obo:OBIB_0000379
    obo:IAO_0000112 "Date/Time Tissue Cryosettes Were Transferred to Storage"^^xsd:string ;
    obo:IAO_0000115 "A data item indicating the date and time when a tissue cassette was transferred to storage after a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time FFPE tissue cassette transferred to storage"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000380
    obo:IAO_0000115 "A personal name that designates the person who performed the dissection of a normal tissue adjacent to a tumor for a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of dissector of normal adjacent tissue to tumor for FFPE"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000381
    obo:IAO_0000115 "A specimen was processed in accordance with the specified SOP where the specified SOP is for a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen was processed in accordance with the FFPE SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000259 .

obo:OBIB_0000382
    obo:IAO_0000115 "A data item indicating the date and time when a specimen tissue was fixed or frozen as part of a formalin-fixed paraffin-embedded (FFPE) process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date and time FFPE tissue was preserved"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000383
    obo:IAO_0000115 "A specimen was processed in accordance with the specified SOP where the specified SOP is for a formalin-fixed paraffin-embedded (FFPE) process and includes less than 1 hour delay in fixation and 23 hour time in fixative."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen was processed in accordance with the FFPE SOP including <1 hour delay to fixation and 23 hour time in fixative"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000259 .

obo:OBIB_0000384
    obo:IAO_0000115 "A comment from tissue procurement made in regards to all non-consent issues related to or creating a limitation on tissues that can be procured including tissue type and reason for restriction."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on procurement site restriction"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000385
    obo:IAO_0000115 "An identifier that specifically identifies a particular specimen image."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen image ID"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000386
    obo:IAO_0000115 "A textual entity that states information relevant to an image from a formalin-fixed paraffin-embedded (FFPE) slide."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on FFPE slide image"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000387
    obo:IAO_0000115 "A personal name that designates the person who was the submitter of a pathology case summary report."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "name of submitting pathologist"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of submitter of pathology case summary report."^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000388
    obo:IAO_0000115 "A data item that reports the calendar date when a pathology case summary report was submitted."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of submission of pathology case summary report"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000389
    obo:IAO_0000115 "A personal name that designates the person who served as the reviewer for quality assurance purposes of a pathology case summary report."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "name of reviewing pathologist"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of reviewer of pathology case summary report."^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000390
    obo:IAO_0000115 "A data item that reports the calendar date when a pathology case summary report was reviewed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of review of pathology case summary report"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000391
    obo:IAO_0000115 "A comment from tissue procurement that was submitted as feedback by a pathologist"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "pathologist submitted specimen procurement feedback"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000392
    obo:IAO_0000112 "The largest dimension of the tumor on the slide measured in millimeters."^^xsd:string ;
    obo:IAO_0000115 "A length measurement datum that is the result of measuring the maximum length of a tumor specimen as presented on a slide."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "greatest tumor dimension on slide"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000408 .

obo:OBIB_0000393
    obo:IAO_0000115 "A data item that is the result of determining the percentage of cross-sectional surface area of an entire specimen slide composed of tumor focus including necrotic tumor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of cross-sectional surface area of entire slide composed of tumor focus"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000394
    obo:IAO_0000115 "A data item that is the result of determining the percentage of tumor nuclei by cell count of the entire specimen slide (number of tumor epithelial cell nuclei as compared to all cell nuclei)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of tumor cellularity by cell count of the entire slide."^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000395
    obo:IAO_0000115 "A data item that is the result of determining the percentage of cross-sectional surface area of an entire specimen slide that is composed of necrotic tissue."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of cross-sectional surface area of entire slide composed of necrotic tissue"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000396
    obo:IAO_0000115 "A data item that is made up of percentages of different histology-based assessments of a tumor slide specimen that in aggregate describe the total tumor surface area (i.e. add up to 100%)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "histologic profile quantitative assessment of tumor slide specimen surface area"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000397
    obo:IAO_0000115 "A data item that is the result of determining the percentage of a tumor slide specimen that is viable based on surface area not including stroma."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of viable tumor slide specimen by surface area"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000398
    obo:IAO_0000115 "A data item that is the result of determining the percentage of a tumor slide specimen that is necrotic based on surface area."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of necrotic tumor slide specimen by surface area"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000399
    obo:IAO_0000115 "A data item that is the result of determining the percentage of a tumor slide specimen that is stroma based on surface area."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of tumor slide specimen stroma by surface area"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000400
    obo:IAO_0000112 "Percent non-cellular component consisting of  mucin, hemorrhage, blood clot, etc."^^xsd:string ;
    obo:IAO_0000115 "A data item that is the result of determining the percentage of a tumor slide specimen that is non-cellular based on surface area."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of non-cellular component of tumor slide specimen by surface area"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000401
    obo:IAO_0000115 "A textual entity that describes the non-cellular component of a tumor slide specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "non-cellular component of tumor slide specimen description"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000402
    obo:IAO_0000115 "An information content entity that is an indicator of whether the local pathology review of a formalin-fixed paraffin-embedded (FFPE) hematoxylin and eosin (H&E)-stained tumor tissue slide confirmed the histological type."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "confirmation of histologic type of FFPE H&E tumor slide"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000403
    obo:IAO_0000112 "This Slide Meets the Microscopic Analysis Criteria of the BPV Project of Necrosis Percentage of <20% AND Tumor Content of _50% Tumor Nuclei"^^xsd:string ;
    obo:IAO_0000115 "An information content entity that is an indicator of whether a formalin-fixed paraffin-embedded (FFPE) slide meets the microscopic analysis criteria with respect to necrosis percentage and tumor content."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE slide meets necrosis percentage and tumor content criteria"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000404
    obo:IAO_0000115 "A textual entity that describes findings upon review of a formalin-fixed paraffin-embedded (FFPE) slide that do not meet microscopic analysis criteria."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE slide findings that do not meet microscopic analysis criteria"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000405
    obo:IAO_0000115 "A textual entity that states information relevant to a review by a pathologist of a formalin-fixed paraffin-embedded (FFPE) slide."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment from pathology review of FFPE slide"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000406
    obo:IAO_0000115 "An information content entity that is an indicator of whether a formalin-fixed paraffin-embedded (FFPE) slide was consistent with findings of diagnostic pathology report."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE slide consistent with findings of diagnostic pathology report"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000407
    obo:IAO_0000115 "A textual entity that describes inconsistencies with findings of diagnostic pathology report upon review of a formalin-fixed paraffin-embedded (FFPE) slide."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "FFPE slide inconsistencies with findings of diagnostic pathology report"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000408
    obo:IAO_0000115 "A personal name that designates the person who served as the pathologist reviewing a specimen slide at an organization conducting specimen collection from organisms."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of reviewing pathologist at organization conducting specimen collection"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000409
    obo:IAO_0000115 "A data item that reports the calendar date when a formalin-fixed paraffin-embedded (FFPE) slide was reviewed by a pathologist."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of FFPE slide review by the pathologist"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000410
    obo:IAO_0000115 "A personal name that designates the person who performed the data entry process for filling in a local pathology review form."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of data entry person for local pathology review form"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000411
    obo:IAO_0000115 "An information content entity that is an indicator of whether examination of a tissue specimen slide revealed the presence of sarcomatoid features."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "presence of sarcomatoid features on specimen slide"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000412
    obo:IAO_0000115 "A textual entity that describes sarcomatoid features observed on a formalin-fixed paraffin-embedded (FFPE) slide."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "sarcomatoid features observed on FFPE slide"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000413
    obo:IAO_0000115 "A personal name that designates the person who received a specimen in a pathology gross room from an associated operating room (OR)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person in gross room receiving OR specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000414
    obo:IAO_0000115 "A specimen transport SOP governing the transport of tissue from the operating room (OR) to the pathology gross room."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen transport from OR to gross room SOP"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000071 .

obo:OBIB_0000415
    obo:IAO_0000115 "An information content entity that is an indicator of whether transport of tissue from the operating room (OR) to the pathology gross room was performed in accordance with the relevant standard operating procedure (SOP)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen transport from OR to gross room was performed as per SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000416
    obo:IAO_0000115 "A textual entity that describes issues with the transport of tissue from the operating room (OR) to the pathology gross room or deviations from the relevant standard operating procedure (SOP)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen transport from OR to gross room issues or deviations from SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000417
    obo:IAO_0000115 "A scalar measurement datum that is the output of a temperature measurement assay occurring in a pathology gross room and performed when a specimen arrived from the operating room (OR)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "temperature in gross room when specimen arrived from OR"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000032 .

obo:OBIB_0000418
    obo:IAO_0000115 "A measurement datum that is the output of an assay of humidity occurring in a pathology gross room and performed when a specimen arrived from the operating room (OR)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "humidity in gross room when specimen arrived from OR"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBIB_0000419
    obo:IAO_0000115 "A personal name that designates the person who performed the gross evaluation of a resected tissue specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of performer of gross evaluation of resected tissue specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000420
    obo:IAO_0000115 "A mass measurement datum that is the output of an assay to measure the weight of a resected tissue specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "resected tissue weight"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "resected tissue specimen mass measurement datum"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000414 .

obo:OBIB_0000421
    obo:IAO_0000115 "An information content entity that is an indicator of whether gross appearance of disease was observed in a resected tissue specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "gross appearance of disease in resected tissue"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000422
    obo:IAO_0000115 "A textual entity that states information relevant to gross evaluation of a resected tissue specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on gross evaluation of resected tissue specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000423
    obo:IAO_0000115 "A diagnosis that is based on the gross evaluation of a resected tissue specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "gross diagnosis of resected tissue"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000073 .

obo:OBIB_0000424
    obo:IAO_0000115 "An information content entity that is an indicator of whether a photograph was taken in the pathology gross room of a resected tissue specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "photograph of tissue was taken in pathology gross room"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000425
    obo:IAO_0000115 "A textual entity that describes the reason no photographs were taken of a resected tissue specimen in the pathology gross room."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "reason for not taking a photograph of resected tissue in pathology gross room"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000426
    obo:IAO_0000115 "An information content entity that is an indicator of whether pathology ink was used to mark the resected tissue specimen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "pathology ink used on resected tissue specimen"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000427
    obo:IAO_0000112 "India ink"^^xsd:string ;
    obo:IAO_0000115 "A processed material that is used to mark the margin of a surgical excision of a resected tissue. It is used to evaluate whether the margin is free of tumor tissue."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "pathology ink"^^xsd:string ;
    obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248492/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "ink used for marking surgical margin"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:OBIB_0000428
    obo:IAO_0000115 "An information content entity that is an indicator of whether a tumor tissue specimen was released to a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "tumor tissue was released to the biobank"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000429
    obo:IAO_0000115 "A textual entity that describes the reason why a tumor tissue specimen was not released to a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "explanation of why tumor tissue specimen was not released to a biobank"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000430
    obo:IAO_0000115 "A data item that is the result of determining the percentage of gross area of necrosis of a specimen sent to a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of gross area of necrosis of a specimen sent to biobank"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000431
    obo:IAO_0000115 "A data item that is the result of determining the percentage of tumor content of a specimen sent to a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "percentage of tumor content of specimen sent to biobank"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000432
    obo:IAO_0000115 "An information content entity that is an indicator of whether a second piece of tumor was collected and released to a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "second piece of tumor tissue was collected"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000433
    obo:IAO_0000115 "An information content entity that is an indicator of whether the dimensions of each specimen meet the criteria specified within the relevant tissue procurement standard operating procedure (SOP)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "dimensions of each specimen meet the criteria specified within the relevant tissue procurement SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000434
    obo:IAO_0000115 "A textual entity that states information relevant to deviations from a tissue procurement SOP with regards to specimen dimensions."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on deviations in specimen dimensions from a tissue procurement SOP"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000435
    obo:IAO_0000115 "An information content entity that is an indicator of whether normal adjacent tissue was released to the biobank in addition to the tumor tissue."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "normal adjacent tissue released to the biobank in addition to tumor tissue"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000436
    obo:IAO_0000115 "A data item indicating the time when a specimen was transferred from a pathology gross room to a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time of specimen transfer from pathology gross room to a biobank"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000438
    obo:IAO_0000115 "An information content entity that is about the status of a tumor and indicates that there has not been a recurrence."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "no recurrence of tumor"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000439
    obo:IAO_0000115 "A comment from tissue procurement that was submitted as part of a follow-up documenting donor outcome after initial specimen collection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "follow-up on donor outcome comment from tissue procurement"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000712 .

obo:OBIB_0000440
    obo:IAO_0000112 "Did the participant sign and date the informed consent for HRRC/IRB#11-279?"^^xsd:string ;
    obo:IAO_0000115 "An information content entity that is an indicator of whether the participant signed and dated a specified informed consent form."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "participant signed and dated informed consent form"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000441
    obo:IAO_0000115 "A textual entity that states information relevant to a review to determine if requirements were met for a specimen collection from a donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case quality review comment"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen collection quality review comment"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000442
    obo:IAO_0000115 "An information content entity that is an indicator of whether the minimum required pre-operative RNA and DNA PAXgene tubes were collected from a donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "minimum required pre-operative RNA and DNA PAXgene tubes were collected"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000443
    obo:IAO_0000115 "An information content entity that is an indicator of whether the desired plasma and serum aliquots were obtained from a specimen donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "desired plasma and serum aliquots were obtained"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000444
    obo:IAO_0000115 "An information content entity that is an indicator of whether a tumor specimen was obtained and processed with a particular FFPE fixation delay protocol to meet the top priority for tissue procurement."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "top priority tumor specimen was obtained and processed with a particular FFPE fixation delay protocol"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000445
    obo:IAO_0000115 "An information content entity that is an indicator of whether a tumor specimen was obtained and processed with a particular FFPE fixation delay protocol other than meeting the top priority for tissue procurement."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "additional tumor specimen was obtained and processed with a particular FFPE fixation delay protocol"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000446
    obo:IAO_0000115 "An information content entity that is an indicator of whether the local pathology review of a hematoxylin (H&E) slide derived from a quality control (QC) formalin-fixed paraffin-embedded (FFPE) tumor tissue was completed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "local pathology review of QC FFPE tumor tissue H&E slide was completed"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000447
    obo:IAO_0000115 "An information content entity that is an indicator of whether the local pathology review was consistent with the findings of the diagnostic pathology report from the site of specimen collection from a donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "local pathology review was consistent with site of tissue procurement diagnostic pathology report"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000448
    obo:IAO_0000115 "An information content entity that is an indicator of whether clinical data entry was completed for a specimen donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case clinical data entry was completed"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor clinical data entry was completed"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000449
    obo:IAO_0000112 "Required tumor module satisfies the project criteria of necrosis percentage of less than 20% and tumor content of greater than or equal to 50% tumor cells by surface area"^^xsd:string ;
    obo:IAO_0000115 "An information content entity that is an indicator of whether the tumor specimen obtained satisfied criteria of necrosis percentage and tumor content of tumor cells by surface area."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "tumor specimen satisfied criteria of necrosis percentage and tumor content"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000450
    obo:IAO_0000115 "An information content entity that is an indicator of whether all requirements for an investigation were met such that a specimen from a particular donor is released for shipment."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case meets all requirements for an investigation and is released for shipment."^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "all requirements for an investigation are met enabling release of specimen for shipment."^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000451
    obo:IAO_0000115 "An information content entity that is an indicator of whether activity related to a particular specimen donor was stopped."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case was stopped"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "activity related to a particular specimen donor was stopped."^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000452
    obo:IAO_0000115 "An activity related to a particular specimen donor was stopped that is because there was not enough blood collected."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case was stopped because not enough blood collected"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "activity related to a particular specimen donor was stopped because not enough blood collected"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000451 .

obo:OBIB_0000453
    obo:IAO_0000115 "An activity related to a particular specimen donor was stopped that is because there was not enough tissue."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case was stopped because not enough tissue"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "activity related to a particular specimen donor was stopped because not enough tissue"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000451 .

obo:OBIB_0000454
    obo:IAO_0000115 "An activity related to a particular specimen donor was stopped that is because the tissue was too necrotic."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case was stopped because tissue was too necrotic"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "activity related to a particular specimen donor was stopped because tissue was too necrotic"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000451 .

obo:OBIB_0000455
    obo:IAO_0000115 "An activity related to a particular specimen donor was stopped that is because the tissue was benign."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case was stopped because tissue was benign"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "activity related to a particular specimen donor was stopped because tissue was benign"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000451 .

obo:OBIB_0000456
    obo:IAO_0000115 "An activity related to a particular specimen donor was stopped that is because the tissue was not released to a biobank."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "case was stopped because tissue was not released to biobank"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "activity related to a particular specimen donor was stopped because tissue was not released to a biobank"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000451 .

obo:OBIB_0000457
    obo:IAO_0000115 "An authorization in which a legally authorized individual is asked to give permission for general research for post mortem specimen donation from a person they represent."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation"^^xsd:string ;
    rdfs:subClassOf obo:ICO_0000046 .

obo:OBIB_0000458
    obo:IAO_0000115 "A role borne by a person who approaches a person's legal representative and informs them of key facts about potential risks and benefits, and asks them for authorization for post-mortem specimen donation  for general research for the person they legally represent."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "obtainer of research authorization for post-mortem specimen donation"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization obtainer role for post mortem donation of specimens from a legally authorized representative"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000459
    obo:IAO_0000115 "An authorization documentation that is the output of a research authorization for post mortem specimen donation."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization documentation for post mortem specimen donation"^^xsd:string ;
    rdfs:subClassOf obo:ICO_0000075 .

obo:OBIB_0000460
    obo:IAO_0000115 "An information content entity that indicates whether research authorization  for post mortem specimen donation was obtained."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation was obtained"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000461
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation establishing agreement for post-mortem donation and use in general research."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "agreed to research authorization for post mortem specimen donation"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization documentation for post mortem specimen donation that is affirmative"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000462
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation establishing the lack of agreement for post-mortem donation and use in general research."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused research authorization documentation for post mortem specimen donation"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization documentation for post mortem specimen donation that is negative"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000463
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation in which the reason authorization was not obtained was due to due to religious reasons."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused due to religious reasons"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained due to religious reasons"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000464
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the donors surgeon did not recommend it."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused due to surgeon's recommendation"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained due to surgeon's recommendation"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000465
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation because the legally authorized representative felt pressured into making a decision."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused because legally authorized representative felt pressured"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative felt pressured"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000466
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative felt too distraught."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused because legally authorized representative too distraught"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative felt too distraught"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000467
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative needed more time to make a decision."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused because legally authorized representative needed more time to make a decision"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative needed more time to make a decision"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000468
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative was uncomfortable with the risks of the request."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused because legally authorized representative was uncomfortable with the risks"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative was uncomfortable with the risks"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000469
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative was afraid the decision might affect the surgery plans for the donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused because legally authorized representative was afraid the decision would affect surgery plans"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative was afraid the decision might affect the surgery plans of donor"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000470
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative did not agree with the activity of biobanking."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused because legally authorized representative did not agree with the activity of biobanking."^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative did not agree with the activity of biobanking"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000471
    obo:IAO_0000115 "A research authorization documentation for post mortem specimen donation in which authorization was not obtained because the the legally authorized representative did not show up to the appointment as scheduled."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "refused  because legally authorized representative did not show up to the appointment as scheduled."^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation not obtained because legally authorized representative did not show up to the appointment as scheduled"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0000472
    obo:IAO_0000115 "A data item that indicates the calendar date on which a research protocol was approved by an Institutional Review Board related to where the research will take place."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "IRB approval date"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of research protocol approval as determined by an institutional review board"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000473
    obo:IAO_0000115 "A data item that indicates the calendar date on which a research protocol expires and becomes inactive as determined by an Institutional Review Board."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "IRB expiration date"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of research protocol expiration as determined by an institutional review board"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000474
    obo:IAO_0000115 "An centrally registered identifier symbol assigned by an Institutional Review Board (IRB) that identifies a particular protocol at a given site."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "protocol number at a site"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "identification number of a protocol at a particular site"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000577 .

obo:OBIB_0000475
    obo:IAO_0000115 "A data item that indicates the calendar date on which the signing  of the research authorization for post mortem specimen donation by the legally authorized individual was witnessed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date that research authorization for post mortem specimen donation was witnessed"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000476
    obo:IAO_0000115 "A data item that indicates the calendar date on which the receipt of the research authorization was verified by study personnel."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "research authorization verification date"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of research authorization verification"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000477
    obo:IAO_0000115 "A personal name that designates who performed the screening of a potential specimen donor for a research study."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "specimen donor  screener"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person screening specimen donors"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000478
    obo:IAO_0000115 "A personal name of an individual with research obtainer role who approaches a person's legal representative and informs them of key facts about potential risks and benefits, and asks them for authorization for post-mortem specimen donation  for research for the person they legally represent."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Research authorization obtainer for post-mortem specimen donation"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "name of person obtaining authorization from legally authorized representative for post-mortem specimen donation"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020015 .

obo:OBIB_0000479
    obo:IAO_0000115 "A data item that indicates the calendar date on which a research authorization was obtained from a specimen donor's legally authorized representative."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "Research authorization date"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date on which research authorization was obtained from legally authorized representative"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000480
    obo:IAO_0000115 "An identifier that uniquely identifies a particular legally authorized representative in a research study."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "legal representative identifier"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "identifier for legally authorized representative"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0000481
    obo:IAO_0000115 "A relationship that may be biological or legal, between the specimen donor and the legally authorized representative who signed the research authorization."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "relationship between person signing research authorization and specimen donor"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000020 .

obo:OBIB_0000482
    obo:IAO_0000115 "A date of birth that signifies the calendar date on which a particular donor of a specimen was born."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "donor's date of birth"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "specimen donor's date of birth"^^xsd:string ;
    rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0004950> .

obo:OBIB_0000483
    obo:IAO_0000115 "Biological sex of the person who bears the role of donor."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "donor's gender"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "donor's biological sex"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000047 .

obo:OBIB_0000484
    obo:IAO_0000115 "A role borne by a person who has died from whom specimens are collected."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "post mortem  donor role"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBIB_0000485
    obo:IAO_0000115 "An age measurement datum that indicates the age of the specimen donor at the time that authorization from their legally authorized representative was obtained."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "age of specimen donor at time that authorization from legally authorized representative was obtained"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBIB_0000486
    obo:IAO_0000115 "An Information content entity that indicates whether the specimen donor  has reached the age of majority as defined by the appropriate regulation."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "age of majority indicator"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indicator of whether specimen donor has reached the age of majority"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000487
    obo:IAO_0000115 "A textual entity that provides additional information that may be relevant to the research authorization verification process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "research authorization comments"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comments related to research authorization process"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000488
    obo:IAO_0000115 "An information content entity that signifies the willingness of an individual to be contacted for a research study."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "recontact indicator"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "willingness to be contacted for a research study"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000489
    obo:IAO_0000115 "An authorization documentation in which a legally authorized individual  agrees to a specific research addendum for the person they represent."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "research addendum authorization"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "agreement to a specified research addendum"^^xsd:string ;
    rdfs:subClassOf obo:ICO_0000075 .

obo:OBIB_0000490
    obo:IAO_0000115 "An authorization documentation for postmortem specimen donation in which specimens are to be used for a specified purpose (e.g., transplantation, research, education)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "authorization for anatomical gift"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "authorization documentation for postmortem specimen donation for a specified purpose"^^xsd:string ;
    rdfs:subClassOf obo:ICO_0000075 .

obo:OBIB_0000491
    obo:IAO_0000115 "An authorization documentation for postmortem specimen donation for a specified purpose which is solely for the purpose of transplantation to another person or persons."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "tissue donation for transplant only"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "authorization for postmortem specimen donation for transplantation purposes only"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000490 .

obo:OBIB_0000492
    obo:IAO_0000115 "An authorization documentation for postmortem specimen donation for a specified purpose which is for transplantation, research, education and the advancement of science."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "tissue donation for transplant and research"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "authorization for postmortem specimen donation for transplantation and research"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000490 .

obo:OBIB_0000493
    obo:IAO_0000115 "An authorization documentation for post mortem specimen donation in which authorization is not obtained for whole brain donation."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "authorization not obtained for whole brain donation"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000490 .

obo:OBIB_0000494
    obo:IAO_0000115 "An authorization documentation for postmortem specimen donation in which authorization includes specific limitations or additional information related to the use of tissue for research."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "tissue use limitations"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "limitations on research authorization for use of donated specimens"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000490 .

obo:OBIB_0000495
    obo:IAO_0000115 "An exclusion criterion that defines whether a metastatic tumor is present, which if met, makes an individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "presence of metastatic tumor exclusion criterion"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBIB_0000496
    obo:IAO_0000115 "An exclusion criterion that defines whether a tumor is larger than a specified size, which if met, makes an individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "presence of a tumor larger than a specified size exclusion criterion"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBIB_0000497
    obo:IAO_0000115 "An inclusion criterion that defines whether the specimen donor has provided authorization to allow for the minimum number of organs/tissue types for a specific study to be collected, which when met, makes a  specimen donor suitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "authorization to collect of minimum number of organ/tissue types for a specific study inclusion criterion"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0000498
    obo:IAO_0000112 "A challenging inclusion criterion is defined as whether it is likely that tissue collection can be started AND the first tissue can be placed in fixative within eight hours of death."^^xsd:string ;
    obo:IAO_0000115 "An inclusion criterion that is defined by whether it is likely that tissue collection can be started AND the first tissue can be placed in fixative within a specified period of time from cardiac cessation or recorded time of death (observed or presumed) for a specimen donor, which if met, makes a specimen donor suitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "tissue collection timing and placed in fixative inclusion criterion"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBIB_0000499
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the time elapsed since radiation therapy prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time since radiation therapy was received prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000500
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the time elapsed since chemotherapy prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time since chemotherapy was received prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000501
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the time elapsed since immunotherapy prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time since immunotherapy was received prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000502
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the time elapsed since hormonal therapy prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time since hormonal therapy was received prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000503
    obo:IAO_0000115 "A data item that reports the calendar date when radiation therapy was received prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of radiation therapy prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000504
    obo:IAO_0000115 "A data item that reports the calendar date when chemotherapy was received prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of chemotherapy prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000505
    obo:IAO_0000115 "A data item that reports the calendar date when immunotherapy was received prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of immunotherapy prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000506
    obo:IAO_0000115 "A data item that reports the calendar date when hormonal therapy was received prior to surgery."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "date of hormonal therapy prior to surgery"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OBIB_0000507
    obo:IAO_0000115 "An Alcohol Use History in which there is no alcohol consumption."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "lifelong non-drinker of alcohol"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C81229 .

obo:OBIB_0000508
    obo:IAO_0000115 "An Alcohol Use History in which there was alcohol consumption in the past but is currently a non-drinker of alcohol."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "current non-drinker of alcohol"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C81229 .

obo:OBIB_0000509
    obo:IAO_0000115 "An Alcohol Use History in which alcohol consumption was equal to or less than 2 drinks per day for men and 1 drink or less per day for women."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "moderate alcohol consumption history"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C81229 .

obo:OBIB_0000510
    obo:IAO_0000115 "An Alcohol Use History in which alcohol consumption was more than 2 drinks per day for men and more than 1 drink per day for women."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "greater than moderate alcohol consumption history"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C81229 .

obo:OBIB_0000511
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the duration of greater than moderate alcohol consumption (more than 2 drinks per day for a man or more than 1 drink per day for a woman) prior to study enrollment."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "duration of greater than moderate alcohol consumption prior to enrollment"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000512
    obo:IAO_0000112 "Less than 100 cigarettes smoked in lifetime"^^xsd:string ;
    obo:IAO_0000115 "A Smoking History in which there was no or an insignificant level of smoking."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "lifelong non-smoker history"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C29719 .

obo:OBIB_0000513
    obo:IAO_0000115 "A Smoking History in which there is current smoking either on a daily or non-daily basis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "current smoker history"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C29719 .

obo:OBIB_0000514
    obo:IAO_0000115 "A Smoking History in which there is no current smoking and has not been smoking for more than 15 years."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "current reformed smoker for more than 15 years history"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C29719 .

obo:OBIB_0000515
    obo:IAO_0000115 "A Smoking History in which there is no current smoking and has not been smoking for less than 15 years."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "current reformed smoker for less than 15 years history"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C29719 .

obo:OBIB_0000516
    obo:IAO_0000115 "A one-dimensional temporal region during which a cancer patient's performance status (general well-being and activities of daily life) was assessed."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "timing of scoring performance status"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000038 .

obo:OBIB_0000517
    obo:IAO_0000115 "A timing of scoring performance status that occurs prior to an operation to treat cancer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "preoperative performance status score"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000516 .

obo:OBIB_0000518
    obo:IAO_0000115 "A timing of scoring performance status that occurs prior to adjuvant therapy to treat cancer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "pre-adjuvant performance status score"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000516 .

obo:OBIB_0000519
    obo:IAO_0000115 "A timing of scoring performance status that occurs after adjuvant therapy to treat cancer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "post adjuvant performance status score"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000516 .

obo:OBIB_0000520
    obo:IAO_0000115 "A textual entity that states additional information relevant to the filling out of a clinical data entry form."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment from clinical data entry form"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000521
    obo:IAO_0000115 "A birth control method that involves the use of an oral hormone-based contraceptive typically taken as a pill."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "pill-based hormonal birth control method"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C106501 .

obo:OBIB_0000522
    obo:IAO_0000115 "A birth control method that involves the injection of hormones."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "injection-based hormonal birth control method"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C106501 .

obo:OBIB_0000523
    obo:IAO_0000115 "A birth control method that involves the use of an intrauterine device (IUD) to deliver hormones."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "IUD-based hormonal birth control method"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "intrauterine device-based hormonal birth control method"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C106501 .

obo:OBIB_0000524
    obo:IAO_0000115 "A birth control method that involves the administration of hormones through a transdermal patch delivery system."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "patch-based hormonal birth control method"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C106501 .

obo:OBIB_0000525
    obo:IAO_0000115 "A birth control method that involves the administration of hormones through a vaginal ring."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "vaginal ring-based hormonal birth control method"^^xsd:string ;
    rdfs:subClassOf obo:NCIT_C106501 .

obo:OBIB_0000526
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the duration of use of hormonally based birth control prior to enrollment in a study."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "duration of hormonal birth control use prior to enrollment"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000527
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the time elapsed since the participant last used hormonally based birth control."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time since last usage of hormonal birth control"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000528
    obo:IAO_0000115 "A textual entity that states additional information relevant to the use of hormonally based birth control."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on the use of hormonally based birth control"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000529
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the duration of hormone replacement therapy prior to enrollment in a study."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "duration of hormone replacement therapy prior to enrollment"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000530
    obo:IAO_0000115 "A time measurement datum that is the result of measuring the time elapsed since the participant last used hormonally replacement therapy."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "time since last usage of hormone replacement therapy"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

obo:OBIB_0000531
    obo:IAO_0000115 "A textual entity that states additional information relevant to the use of hormone replacement therapy."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on the use of hormone replacement therapy"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000532
    obo:IAO_0000115 "A textual entity that states additional information relevant to the history of exposure to environmental and workplace carcinogens."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "comment on exposure to environmental and workplace carcinogens"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000300 .

obo:OBIB_0000533
    obo:IAO_0000115 "A risk factor that is associated with increased likelihood of colorectal cancer."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "colorectal cancer risk factor"^^xsd:string ;
    rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003919> .

obo:OBIB_0000534
    obo:IAO_0000112 "a diet that is high in beef, lamb, or liver and hot dogs and some luncheon meats."^^xsd:string ;
    obo:IAO_0000115 "A colorectal cancer risk factor that is having a diet that is high in red meats and processed meats."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "high meat diet colorectal cancer risk factor"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000533 .

obo:OBIB_0000535
    obo:IAO_0000115 "A colorectal cancer risk factor that is having been obese."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "obesity colorectal cancer risk factor"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000533 .

obo:OBIB_0000536
    obo:IAO_0000115 "A colorectal cancer risk factor that is having Type II diabetes mellitus."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "Type II diabetes colorectal cancer risk factor"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000533 .

obo:OBIB_0000537
    obo:IAO_0000115 "A colorectal cancer risk factor that is having had colorectal polyps."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "previous colorectal polyps colorectal cancer risk factor"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000533 .

obo:OBIB_0000538
    obo:IAO_0000115 "A colorectal cancer risk factor that is having familial adenomatous polyposis or having a family member with familial adenomatous polyposis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "familial adenomatous polyposis colorectal cancer risk factor"^^xsd:string ;
    rdfs:subClassOf obo:OBIB_0000533 .

obo:OBIB_0000539
    obo:IAO_0000115 "A hormone replacement therapy where the hormone is estrogen."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "estrogen alone hormone replacement therapy"^^xsd:string ;
    rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003961> .

obo:OBIB_0000540
    obo:IAO_0000115 "A hormone replacement therapy where the hormones are estrogen and progestin."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "estrogen with progestin hormone replacement therapy"^^xsd:string ;
    rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003961> .

obo:OBIB_0000541
    obo:IAO_0000115 "A hormone replacement therapy where the hormone is progestin."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "progestin alone hormone replacement therapy"^^xsd:string ;
    rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003961> .

obo:OBIB_0000542
    obo:IAO_0000115 "A hormone replacement therapy where the hormone is testosterone."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "testosterone hormone replacement therapy"^^xsd:string ;
    rdfs:subClassOf <http://www.ebi.ac.uk/efo/EFO_0003961> .

obo:OBIB_0000543
    obo:IAO_0000115 "A clinical history in which there is a history of sepsis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of sepsis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000544
    obo:IAO_0000115 "A clinical history in which there is a history of pneumonia."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of pneumonia"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000545
    obo:IAO_0000115 "A clinical history in which there is a history of open wounds."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of open wounds"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000546
    obo:IAO_0000115 "A clinical history in which there is a history of a high unexplained fever ."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of high unexplained fever"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000547
    obo:IAO_0000115 "A clinical history in which there is a history of positive blood cultures."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of positive blood cultures"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000548
    obo:IAO_0000115 "A clinical history in which there is a history of abnormal white blood cell levels."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of abnormal white blood cell levels"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000549
    obo:IAO_0000115 "A clinical history in which there is a history of fungal infections."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of fungal infections"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000550
    obo:IAO_0000115 "A clinical history in which there is a history of the presence of ascites fluid."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of ascites"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000551
    obo:IAO_0000115 "A clinical history in which there is a history of cellulitis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of cellulitis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000552
    obo:IAO_0000115 "A clinical history in which there is a history of receiving a blood transfusion while in another country."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of blood transfusion in foreign country"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000553
    obo:IAO_0000115 "A clinical  history in which there is a history of receiving a human tissue or organ transplant ."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of human tissue transplant"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000554
    obo:IAO_0000115 "A clinical  history in which there is a history of receiving an animal tissue or organ xenotransplant."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of animal tissue xenotransplant"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000555
    obo:IAO_0000115 "A clinic history in which there is a history  of a recent of smallpox vaccination."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of smallpox vaccination"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000556
    obo:IAO_0000115 "A clinical history in which there is a history of contact with someone who recently had smallpox."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "a clinical history of contact with someone with smallpox"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000557
    obo:IAO_0000112 "The patient had a clinical history of dialysis treatment three times a week for longer than one month."^^xsd:string ;
    obo:IAO_0000115 "A clinical history in which there is a history of significant regular dialysis treatment."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of dialysis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000558
    obo:IAO_0000115 "A clinical history in which there is a current diagnosis of cancer at death."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of cancer at death"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000559
    obo:IAO_0000112 "A clinical history in which there is a history of cancer diagnosis in the preceding five years."^^xsd:string ;
    obo:IAO_0000115 "A clinical history in which there is a history of cancer diagnosis within a specified time frame."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of cancer within a time period before death"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000560
    obo:IAO_0000115 "A clinical history in which there is a history of tuberculosis ."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of tuberculosis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000561
    obo:IAO_0000115 "A  clinical history in which there was active meningitis at death."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of meningitis at death"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000562
    obo:IAO_0000115 "A clinical history in which there was active encephalitis at death."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of encephalitis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000563
    obo:IAO_0000115 "A clinical history in which there is a history of long term steroid use."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of long term steroid use"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000564
    obo:IAO_0000115 "A clinical history in which there is a history of osteomyelitis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of osteomyelitis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000565
    obo:IAO_0000115 "A clinical history in which there is a history of unexplained seizures."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of unexplained seizures"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000566
    obo:IAO_0000115 "A clinical history in which there is a history of unexplained weakness and fatigue described as flu-like symptoms."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of unexplained weakness and fatigue"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000567
    obo:IAO_0000115 "A clinical history in which there is a history of exposure to toxic substances that may have led to chronic conditions."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of exposure to toxins"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000568
    obo:IAO_0000112 "A clinical history in which there is a history of an animal bite in the last 12 months, from an animal suspected to have rabies."^^xsd:string ;
    obo:IAO_0000115 "A clinical history in which there is a history of an animal bite in recent past, from an animal suspected to have rabies."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of exposure to rabies"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000569
    obo:IAO_0000115 "An information content entity  that indicates whether an individual ever used heroin in any manner."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of heroin use"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000570
    obo:IAO_0000112 "The participant's clinical history included cocaine use in the last 5 years."^^xsd:string ;
    obo:IAO_0000115 "An information content entity that indicates whether an individual recently used cocaine."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "Indication of recent cocaine use"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000571
    obo:IAO_0000115 "An information content entity in that indicates whether a man has ever had sex with another man."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of male homosexual sexual activity"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000572
    obo:IAO_0000112 "An information content entity in which the individual used illegal injectable drugs in the last 5 years."^^xsd:string ;
    obo:IAO_0000115 "An information content entity that indicates whether an individual recently used injectable drugs for non-medical purposes in the recent past."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "an indication of illegal injectable drug use"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000573
    obo:IAO_0000115 "A clinical history in which there is a history of clotting disorders, such as hemophilia, requiring treatment with human-derived clotting factors."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of clotting disorders"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000574
    obo:IAO_0000115 "A clinical history in which there is a history of growth hormone use."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of growth hormone use"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000575
    obo:IAO_0000115 "A clinical history in which there is a history of the donor not being able to be tested for Human Immunodeficiency Virus (HIV) because of hemodilution."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of inability to have Human Immunodeficiency Virus testing due to hemodilution"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000576
    obo:IAO_0000115 "A clinical history in which there is a history of unexplained weight loss."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of unexplained weight loss"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000577
    obo:IAO_0000115 "A clinical history in which there is a history of night sweats."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of night sweats"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000578
    obo:IAO_0000115 "A clinical history in which there is a of blue or purple spots on the skin or mucus membranes (typical of Kaposi's sarcoma)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of blue or purple spots on skin or mucous membranes"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000579
    obo:IAO_0000112 "A clinical history in which there is a history of unexplained lymphadenopathy lasting more than one month."^^xsd:string ;
    obo:IAO_0000115 "A clinical history in which there is a history of unexplained lymphadenopathy of a specific duration."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of unexplained lymphadenopathy"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000580
    obo:IAO_0000112 "A clinical history in which there is a history of fever of at least 38.6 Celsius for more than 10 days."^^xsd:string ;
    obo:IAO_0000115 "A clinical history in which there is a history of  fever of at least 38.6 Celsius for a specified duration."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of a prolonged fever"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000581
    obo:IAO_0000115 "A clinical history in which there is are active signs of unexplained persistent cough and/or shortness of breath."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of an unexplained cough or shortness of breath"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000582
    obo:IAO_0000115 "A clinical history in which there is a history of opportunistic infections."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of opportunistic infections"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000583
    obo:IAO_0000115 "A clinical history in which there is a history of sexually transmitted diseases"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of sexually transmitted disease"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000584
    obo:IAO_0000115 "A clinical history in which there is a history of drug abuse."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of drug abuse"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000585
    obo:IAO_0000115 "A clinical history in which there is a history of a Severe Acute Respiratory Syndrome (SARS) diagnosis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of Severe Acute Respiratory Syndrome"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000586
    obo:IAO_0000115 "A clinical history in which there is a history of recent contact with someone who has Severe Acute Respiratory Syndrome (SARS)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of exposure to Severe Acute Respiratory Syndrome"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000587
    obo:IAO_0000115 "A clinical history in which there is a history of West Nile Virus (WNV) infection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of West Nile Virus"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000588
    obo:IAO_0000115 "A clinical history in which there is a history of contact with a human or animal who has West Nile Virus (WNV)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of West Nile Virus exposure"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000589
    obo:IAO_0000112 "A clinical history in which there is a history of  current gonorrhea infection or treatment for gonorrhea in the last 12 months."^^xsd:string ;
    obo:IAO_0000115 "A clinical history in which there is a history of active gonorrhea infection or treatment for gonorrhea in the recent past."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of gonorrhea"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000590
    obo:IAO_0000112 "A clinical history in which there is a history of  current syphilis infection or treatment for syphilis in the last 12 months."^^xsd:string ;
    obo:IAO_0000115 "A clinical history in which there is a history of active syphilis infection or treatment for syphilis in the recent past."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of syphilis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000591
    obo:IAO_0000115 "A clinical history in which there is a history of Hepatitis B infection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of Hepatitis B"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000592
    obo:IAO_0000115 "A clinical history in which there is a history of Hepatitis C infection."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of Hepatitis C"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000593
    obo:IAO_0000115 "A clinical history in which there is a history of Human Immunodeficiency Virus (HIV)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of Human Immunodeficiency Virus"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000594
    obo:IAO_0000115 "A clinical history in which there is a history of systemic lupus"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of lupus"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000595
    obo:IAO_0000115 "A clinical history in which there is a history of sarcoidosis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of sarcoidosis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000596
    obo:IAO_0000115 "A clinical history in which there is a history of scleroderma."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of scleroderma"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000597
    obo:IAO_0000115 "A clinical history in which there is a history of Reye's Syndrome."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of Reye's Syndrome"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000598
    obo:IAO_0000115 "A clinical history in which there is a history of rheumatoid arthritis."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of rheumatoid arthritis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000599
    obo:IAO_0000115 "A clinical history in which there is a history of idiopathic heart disease."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of idiopathic heart disease"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000600
    obo:IAO_0000115 "A clinical history in which there is a history of Alzheimer's Disease."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of Alzheimer's disease"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000601
    obo:IAO_0000115 "A clinical history in which there is a history of dementia with unknown cause  that is not caused by a previous Cerebrovascular Accident (CVA) infection, head trauma or brain tumor)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of dementia of unknown cause"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000602
    obo:IAO_0000115 "A clinical history in which there is a history of Multiple Sclerosis (MS)."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of Multiple Sclerosis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000603
    obo:IAO_0000115 "A clinical history in which there is a history of Amyotrophic Lateral Sclerosis (ALS)"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "clinical history of Amyotrophic Lateral Sclerosis"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBIB_0000604
    obo:IAO_0000112 "An information content entity in which there is an indication of whether an individual resided on a Northern European military base for 6 months from 1980-1990."^^xsd:string ;
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual resided on a Northern European military base for a specified duration during a specific time frame."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of having resided in a Northern European military base"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000605
    obo:IAO_0000112 "An information content entity in which there is an indication of whether an individual resided in Europe from 1980-1996."^^xsd:string ;
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual resided in Europe during a specific time frame"^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of having resided in Europe during a specific time frame"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000606
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual ever performed sexual acts in exchange for money or drugs."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of performing sexual acts in exchange for money or drugs"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000607
    obo:IAO_0000112 "An information content entity in which there is an indication of whether an individual spent more than 72 hours in a correction/detention center in the last year."^^xsd:string ;
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual spent more than 72 hours in a correction/detention center in the recent past."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "indication of jail time"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of time in jail"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000608
    obo:IAO_0000112 "An information content entity in which there is an indication of whether an individual had a tattoo done in a state that does not regulate tattoo parlors, in the last year."^^xsd:string ;
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual had a tattoo done in a state that does not regulate tattoo parlors, in the recent past."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of a tattoo from unregulated tattoo parlor"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000609
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual has used prescription pills that were not prescribed to them."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of illegal prescription drug use"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000610
    obo:IAO_0000112 "An information content entity in which there is an indication of whether an individual has used illegal intravenous drugs in the past 5 years."^^xsd:string ;
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual has used illegal intravenous drugs  in a specified time frame."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of intravenous drug use"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000611
    obo:IAO_0000112 "An information content entity in which there is an indication of whether an individual spent a total of three or more months in the United Kingdom, any time from 1980-1996."^^xsd:string ;
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual spent a total of three or more months in the United Kingdom, in a specified time frame."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of having lived in the United Kingdom during specific time frame"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000612
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual has signs of non-professional  body piercing."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of body piercing from non-professional"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000613
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual has signs of non-professional  tattoos."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of tattoo from non-professional"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000614
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual was a resident of a state-run group home at time of death."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of residence in state-run group home at time of death"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000615
    obo:IAO_0000112 "An indication of whether an individual lived in Europe for at least 5 years since 1980."^^xsd:string ;
    obo:IAO_0000115 "An information content entity in which there is an indication of whether an individual lived in Europe for at least 5 years during a specific time."^^xsd:string ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a owl:Class ;
    rdfs:label "indication of having resided in Europe during specific time frame"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBIB_0000616
    obo:IAO_0000115 """A biobank is a collections of samples of biological substances
(e.g. tissue, blood, DNA) which are linked to data about the samples and their donors. They have a dual nature as collections of samples and data."""@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000119 "definition derived from the definition of 'human biobank', based on http://www.ethikrat.org/files/der_opinion_human-biobanks.pdf"@en ;
    a owl:Class ;
    rdfs:label "biobank"@en ;
    rdfs:subClassOf obo:BFO_0000027 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000027
                        [
                            a owl:Restriction ;
                            owl:allValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:OBI_0100051
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:RO_0000056 ;
                                        owl:someValuesFrom obo:OBI_0302893
                                    ]
                                )
                            ] ;
                            owl:onProperty obo:BFO_0000051
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000178
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000056 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:OBI_0302914
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0000299 ;
                                        owl:someValuesFrom [
                                            a owl:Class ;
                                            owl:intersectionOf (obo:IAO_0000100
                                                [
                                                    a owl:Restriction ;
                                                    owl:onProperty obo:IAO_0000136 ;
                                                    owl:someValuesFrom [
                                                        a owl:Class ;
                                                        owl:intersectionOf (obo:BFO_0000027
                                                            [
                                                                a owl:Restriction ;
                                                                owl:allValuesFrom obo:OBI_0100051 ;
                                                                owl:onProperty obo:BFO_0000051
                                                            ]
                                                        )
                                                    ]
                                                ]
                                            )
                                        ]
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBIB_0000735 ;
                owl:someValuesFrom obo:OBIB_0000623
            ]
        )
    ] .

obo:OBIB_0000617
    obo:IAO_0000115 """A human biobank is a collections of samples of human body substances
(e.g. Tissue, blood, DNA) which are linked to personal data and socio
deographic information about the donors of the material. They have a dual
nature as collections of samples and data.\""""@en ;
    obo:IAO_0000119 "Deutscher Ethikrat: Human biobanks for research. Opinion. Berlin, 2010. http://www.ethikrat.org/files/der_opinion_human-biobanks.pdf" ;
    a owl:Class ;
    rdfs:label "human biobank"@en ;
    rdfs:subClassOf obo:OBIB_0000616 .

obo:OBIB_0000618
    obo:IAO_0000115 "The part of a sample collection or study contact's adress denoting a settlement."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection/Study contact city"@en ;
    a owl:Class ;
    rdfs:label "settlement part of address of sample collection or study contact"@en ;
    rdfs:subClassOf obo:OBIB_0000641 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000641
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000422
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBIB_0000734 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:NCBITaxon_9606
                                    [
                                        a owl:Class ;
                                        owl:unionOf ([
                                                a owl:Class ;
                                                owl:intersectionOf ([
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:BFO_0000050 ;
                                                        owl:someValuesFrom obo:BFO_0000027
                                                    ]
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:OBIB_0000733 ;
                                                        owl:someValuesFrom [
                                                            a owl:Class ;
                                                            owl:intersectionOf (obo:BFO_0000027
                                                                [
                                                                    a owl:Restriction ;
                                                                    owl:allValuesFrom obo:OBI_0100051 ;
                                                                    owl:onProperty obo:BFO_0000051
                                                                ]
                                                            )
                                                        ]
                                                    ]
                                                )
                                            ]
                                            [
                                                a owl:Class ;
                                                owl:intersectionOf ([
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:RO_0000053 ;
                                                        owl:someValuesFrom obo:OBIB_0000670
                                                    ]
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:RO_0000056 ;
                                                        owl:someValuesFrom obo:OBI_0000471
                                                    ]
                                                )
                                            ]
                                        )
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000619
    obo:IAO_0000115 "An identifier in natural language referring  to a biobank."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Name of biobank"@en ;
    a owl:Class ;
    rdfs:label "biobank proper name"@en ;
    rdfs:subClassOf obo:IAO_0020000 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0020012 ;
        owl:someValuesFrom obo:OBIB_0000616
    ] .

obo:OBIB_0000620
    obo:IAO_0000115 "An identifier that consists of two letters, is part of the ISO 3166-1, and designates countries, dependent territories, and special areas of geographical interest."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/ISO_3166-1_alpha-2" ;
    a owl:Class ;
    rdfs:comment "Two-letter country codes defined in ISO 3166-1, part of the ISO 3166 standard published by the International Organization for Standardization (ISO), to designate countries, dependent territories, and special areas of geographical interest."@en ;
    rdfs:label "ISO 3166-1 alpha-2 code"@en ;
    rdfs:subClassOf obo:IAO_0020000, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0020012 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:GEO_000000006
                obo:GEO_000000396
            )
        ]
    ] .

obo:OBIB_0000621
    obo:IAO_0000115 "A biobank identifier that has an ISO 3166-1 alpha-2 code as a part."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank ID"@en ;
    a owl:Class ;
    rdfs:comment "Textual string of letters starting with the country code (according to standard ISO1366 alpha2) followed by the underscore “_” and post-fixed by a biobank ID or name specified by its juristic person (nationally specific)."@en ;
    rdfs:label "biobank idenfier with ISO 3166-1 alpha-2 code"@en ;
    rdfs:subClassOf obo:OBIB_0000619, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom obo:OBIB_0000620
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0020012 ;
                owl:someValuesFrom obo:OBIB_0000616
            ]
        )
    ] .

obo:OBIB_0000622
    obo:IAO_0000115 "The ISO 3166-1 alpha-2 code that is part of the sample collection or study contact's postal address."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection/Study contact country"@en ;
    a owl:Class ;
    rdfs:label "ISO 3166-1 alpha-2 code for sample collection or study contact"@en ;
    rdfs:subClassOf obo:OBIB_0000620 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000620
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000422
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBIB_0000734 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:NCBITaxon_9606
                                    [
                                        a owl:Class ;
                                        owl:unionOf ([
                                                a owl:Class ;
                                                owl:intersectionOf ([
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:BFO_0000050 ;
                                                        owl:someValuesFrom obo:BFO_0000027
                                                    ]
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:OBIB_0000733 ;
                                                        owl:someValuesFrom [
                                                            a owl:Class ;
                                                            owl:intersectionOf (obo:BFO_0000027
                                                                [
                                                                    a owl:Restriction ;
                                                                    owl:allValuesFrom obo:OBI_0100051 ;
                                                                    owl:onProperty obo:BFO_0000051
                                                                ]
                                                            )
                                                        ]
                                                    ]
                                                )
                                            ]
                                            [
                                                a owl:Class ;
                                                owl:intersectionOf ([
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:RO_0000053 ;
                                                        owl:someValuesFrom obo:OBIB_0000670
                                                    ]
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:RO_0000056 ;
                                                        owl:someValuesFrom obo:OBI_0000471
                                                    ]
                                                )
                                            ]
                                        )
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000623
    obo:IAO_0000115 "An organization bearing legal personality that owns or adminstrates a biobank."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "biobank juristic person"@en ;
    a owl:Class ;
    rdfs:label "biobank organization"@en ;
    rdfs:subClassOf obo:OBI_0000245, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0001688 ;
        owl:someValuesFrom obo:OBIB_0000626
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000245
            [
                a owl:Class ;
                owl:unionOf ([
                        a owl:Restriction ;
                        owl:onProperty obo:OBIB_0000732 ;
                        owl:someValuesFrom obo:OBIB_0000616
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBIB_0000733 ;
                        owl:someValuesFrom obo:OBIB_0000616
                    ]
                )
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000053 ;
                owl:someValuesFrom obo:OMRSE_00000038
            ]
        )
    ] .

obo:OBIB_0000624
    obo:IAO_0000115 "A planned process that involves a human being and is intended to initiate a communication with another human being."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:comment "Contacting is the process of one human being starting a communication process with another human being. Contacting can be done using all modes of communication used by humans."@en ;
    rdfs:label "contacting"@en ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000625
    obo:IAO_0000115 "A role borne by a human being that is part of an group of individuals and acts as contact person for the group. This role gets realized by the bearer being a participant in a contacting process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "contact role"@en ;
    rdfs:subClassOf obo:OMRSE_00000024, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000054 ;
        owl:someValuesFrom obo:OBIB_0000624
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBIB_0000624 ;
        owl:onProperty obo:BFO_0000054
    ], [
        a owl:Restriction ;
        owl:allValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:NCBITaxon_9606
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000846 ;
                    owl:someValuesFrom obo:OBI_0000245
                ]
            )
        ] ;
        owl:onProperty obo:RO_0000052
    ] .

obo:OBIB_0000626
    obo:IAO_0000115 "A human being that is member of a biobank organization and bears the organization contact role."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "biobank contact person"@en ;
    rdfs:subClassOf obo:NCBITaxon_9606 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:NCBITaxon_9606
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000846 ;
                owl:someValuesFrom obo:OBIB_0000623
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000053 ;
                owl:someValuesFrom obo:OBIB_0000669
            ]
        )
    ] .

obo:OBIB_0000627
    obo:IAO_0000115 "A personal name that designates the person acting as contact for a biobank."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank contact person"@en ;
    a owl:Class ;
    rdfs:label "name of biobank contact person"@en ;
    rdfs:subClassOf obo:IAO_0020015 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0020012 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:NCBITaxon_9606
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000846 ;
                    owl:someValuesFrom obo:OBIB_0000623
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000053 ;
                    owl:someValuesFrom obo:OBIB_0000669
                ]
            )
        ]
    ] .

obo:OBIB_0000628
    obo:IAO_0000115 "An email address for the purpose of contacting a biobank contact person."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank contact email"@en ;
    a owl:Class ;
    rdfs:label "email address of biobank contact person"@en ;
    rdfs:subClassOf obo:IAO_0000429 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000429
            [
                a owl:Restriction ;
                owl:onProperty obo:OBIB_0000734 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:NCBITaxon_9606
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000846 ;
                            owl:someValuesFrom obo:OBIB_0000623
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000053 ;
                            owl:someValuesFrom obo:OBIB_0000669
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000629
    obo:IAO_0000115 "Postal address used as a directive for deliveries to the biobank contact person."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "postal address of biobank contact person"@en ;
    rdfs:subClassOf obo:IAO_0000422 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000422
            [
                a owl:Restriction ;
                owl:onProperty obo:OBIB_0000734 ;
                owl:someValuesFrom obo:OBIB_0000626
            ]
        )
    ] .

obo:OBIB_0000630
    obo:IAO_0000115 "An organization with a specific responsibility that is a part of a larger organization with a specific responsibility."@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Department" ;
    a owl:Class ;
    rdfs:label "department"@en ;
    rdfs:subClassOf obo:OBI_0000245, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:complementOf [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000053 ;
                    owl:someValuesFrom obo:OMRSE_00000038
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000846 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000245
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000053 ;
                            owl:someValuesFrom obo:OMRSE_00000038
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000631
    obo:IAO_0000115 "A department that has a contact person for a biobank as an organizational member."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank contact department"@en ;
    a owl:Class ;
    rdfs:label "department of biobank contact"@en ;
    rdfs:subClassOf obo:OBIB_0000630 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000630
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0001688 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:NCBITaxon_9606
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000846 ;
                            owl:someValuesFrom obo:OBIB_0000623
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000053 ;
                            owl:someValuesFrom obo:OBIB_0000669
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000632
    obo:IAO_0000115 "A CRID that constitutes a reference to an Internet resource."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "uri"@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Uniform_resource_locator" ;
    a owl:Class ;
    rdfs:label "unique resource locator"@en ;
    rdfs:subClassOf obo:IAO_0000578 .

obo:OBIB_0000633
    obo:IAO_0000115 "A unique resource locator referring to the homepage of a biobank."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank URL"@en ;
    a owl:Class ;
    rdfs:label "biobank's unique resource locator"@en ;
    rdfs:subClassOf obo:OBIB_0000632 .

obo:OBIB_0000634
    obo:IAO_0000115 "A telephone number  is a textual entity consisting of a sequence of digits used to call from one telephone line to another in a public switched telephone network."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Telephone_number" ;
    a owl:Class ;
    rdfs:comment "MB: This class should probably be a subclass to CRID. However, the textual definition of CRID right now states that each instance has the CRID identifier as a part. This is not the case for telephone numbers. Therefore, they cannot be subsumed under CRID now. I am looking into changing IAO accordingly. Once that is done, the class ought to be a subclass of CRID."@en ;
    rdfs:label "telephone number"@en ;
    rdfs:subClassOf obo:IAO_0000300, [
        a owl:Restriction ;
        owl:allValuesFrom obo:IAO_0000029 ;
        owl:onProperty obo:BFO_0000051
    ] .

obo:OBIB_0000635
    obo:IAO_0000115 "A telephone number that is contact information about a biobank contact person."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank contact phone"@en ;
    a owl:Class ;
    rdfs:label "telephone number of biobank contact"@en ;
    rdfs:subClassOf obo:OBIB_0000634 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000634
            [
                a owl:Restriction ;
                owl:onProperty obo:OBIB_0000734 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:NCBITaxon_9606
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000846 ;
                            owl:someValuesFrom obo:OBIB_0000623
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000053 ;
                            owl:someValuesFrom obo:OBIB_0000669
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000636
    obo:IAO_0000115 "An identifier denoting a post-office box."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "post-office box number"@en ;
    rdfs:subClassOf obo:IAO_0020000 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0020000
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:OBIB_0000637 ;
                owl:onProperty obo:IAO_0000219
            ]
        )
    ] .

obo:OBIB_0000637
    obo:IAO_0000115 "A post-office box is material entity that is a box on the premises of a post office station and is uniquely addressable."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Post-office_box" ;
    a owl:Class ;
    rdfs:label "post-office box"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000638
    obo:IAO_0000115 "A telephone number that is contact information about a sample collection or study contact person."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection/Study contact phone"@en ;
    a owl:Class ;
    rdfs:label "telephone number of sample collection or study contact"@en ;
    rdfs:subClassOf obo:OBIB_0000634 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000634
            [
                a owl:Restriction ;
                owl:onProperty obo:OBIB_0000734 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:NCBITaxon_9606
                        [
                            a owl:Class ;
                            owl:unionOf ([
                                    a owl:Class ;
                                    owl:intersectionOf ([
                                            a owl:Restriction ;
                                            owl:onProperty obo:BFO_0000050 ;
                                            owl:someValuesFrom obo:BFO_0000027
                                        ]
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:OBIB_0000733 ;
                                            owl:someValuesFrom [
                                                a owl:Class ;
                                                owl:intersectionOf (obo:BFO_0000027
                                                    [
                                                        a owl:Restriction ;
                                                        owl:allValuesFrom obo:OBI_0100051 ;
                                                        owl:onProperty obo:BFO_0000051
                                                    ]
                                                )
                                            ]
                                        ]
                                    )
                                ]
                                [
                                    a owl:Class ;
                                    owl:intersectionOf ([
                                            a owl:Restriction ;
                                            owl:onProperty obo:RO_0000053 ;
                                            owl:someValuesFrom obo:OBIB_0000670
                                        ]
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:RO_0000056 ;
                                            owl:someValuesFrom obo:OBI_0000471
                                        ]
                                    )
                                ]
                            )
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000639
    obo:IAO_0000115 "The postal code that is part of the postal address of the biobank contact person."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank contact ZIP"@en ;
    a owl:Class ;
    rdfs:label "postal code of biobank contact"@en ;
    rdfs:subClassOf obo:IAO_0000646 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000646
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000422
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBIB_0000734 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:NCBITaxon_9606
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0000846 ;
                                        owl:someValuesFrom obo:OBIB_0000623
                                    ]
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:RO_0000053 ;
                                        owl:someValuesFrom obo:OBIB_0000669
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000640
    obo:IAO_0000115 "The ISO 3166-1 alpha-2 code that is part of the biobank contact person's postal address."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "ISO 3166-1 alpha-2 code for biobank contact person"@en ;
    rdfs:subClassOf obo:OBIB_0000620 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000620
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000422
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBIB_0000734 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:NCBITaxon_9606
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0000846 ;
                                        owl:someValuesFrom obo:OBIB_0000623
                                    ]
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:RO_0000053 ;
                                        owl:someValuesFrom obo:OBIB_0000669
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000641
    obo:IAO_0000115 "A textual entity that is part of a postal address and denotes a human settlement for the purpose of delivering mail."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "settlement part of address"@en ;
    rdfs:subClassOf obo:IAO_0000300, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom obo:GAZ_00000448
    ] .

obo:OBIB_0000642
    obo:IAO_0000115 "The part of a biobank contact's adress denoting a settlement."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank contact city"@en ;
    a owl:Class ;
    rdfs:label "settlement part of address biobank contact"@en ;
    rdfs:subClassOf obo:OBIB_0000641 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000641
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000422
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBIB_0000734 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:NCBITaxon_9606
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0000846 ;
                                        owl:someValuesFrom obo:OBIB_0000623
                                    ]
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:RO_0000053 ;
                                        owl:someValuesFrom obo:OBIB_0000669
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000643
    obo:IAO_0000115 "A textual entity that is part of a postal address and specifies the location inside the settlement (which is specified by another part of the address). This can be a street name and a house number, or just a number or a post-office box number."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "intra-settlement specification part of address"@en ;
    rdfs:subClassOf obo:IAO_0000300 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000300
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom obo:IAO_0000422
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0020000
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:IAO_0020012 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:unionOf (obo:OBIB_0000637
                                    obo:OBIB_0000653
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000644
    obo:IAO_0000115 "An intra-settlement specification part of address that is part of a biobank contact's postal address."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank contact address"@en ;
    a owl:Class ;
    rdfs:label "intra-settlement specification part of address of biobank contact"@en ;
    rdfs:subClassOf obo:OBIB_0000643 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000643
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000422
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBIB_0000734 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:NCBITaxon_9606
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0000846 ;
                                        owl:someValuesFrom obo:OBIB_0000623
                                    ]
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:RO_0000053 ;
                                        owl:someValuesFrom obo:OBIB_0000669
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000645
    obo:IAO_0000115 "A object aggregate that consists of specimens, participates in a study and is part of a biobank."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Hosted studies"@en ;
    a owl:Class ;
    rdfs:label "hosted study collection"@en ;
    rdfs:subClassOf obo:BFO_0000027, obo:OBI_0002076 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:BFO_0000027
                    [
                        a owl:Restriction ;
                        owl:allValuesFrom obo:OBI_0100051 ;
                        owl:onProperty obo:BFO_0000051
                    ]
                )
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom obo:OBIB_0000616
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000056 ;
                owl:someValuesFrom obo:OBI_0000471
            ]
        )
    ] .

obo:OBIB_0000646
    obo:IAO_0000115 "The proper name that designates a hosted study collection."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "name of hosted study collection"@en ;
    rdfs:subClassOf obo:OBIB_0000001 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0020000
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0020012 ;
                owl:someValuesFrom obo:OBIB_0000645
            ]
        )
    ] .

obo:OBIB_0000647
    obo:IAO_0000115 "An email address for the purpose of contacting a sample collection or study contact person."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection/Study contact email"@en ;
    a owl:Class ;
    rdfs:label "email address of sample collection or study contact"@en ;
    rdfs:subClassOf obo:IAO_0000429 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000429
            [
                a owl:Restriction ;
                owl:onProperty obo:OBIB_0000734 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:NCBITaxon_9606
                        [
                            a owl:Class ;
                            owl:unionOf ([
                                    a owl:Class ;
                                    owl:intersectionOf ([
                                            a owl:Restriction ;
                                            owl:onProperty obo:BFO_0000050 ;
                                            owl:someValuesFrom obo:BFO_0000027
                                        ]
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:OBIB_0000733 ;
                                            owl:someValuesFrom [
                                                a owl:Class ;
                                                owl:intersectionOf (obo:BFO_0000027
                                                    [
                                                        a owl:Restriction ;
                                                        owl:allValuesFrom obo:OBI_0100051 ;
                                                        owl:onProperty obo:BFO_0000051
                                                    ]
                                                )
                                            ]
                                        ]
                                    )
                                ]
                                [
                                    a owl:Class ;
                                    owl:intersectionOf ([
                                            a owl:Restriction ;
                                            owl:onProperty obo:RO_0000053 ;
                                            owl:someValuesFrom obo:OBIB_0000670
                                        ]
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:RO_0000056 ;
                                            owl:someValuesFrom obo:OBI_0000471
                                        ]
                                    )
                                ]
                            )
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000648
    obo:IAO_0000115 "A textual entity describing a study aim or a sample collection."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample collection or study description"@en ;
    a owl:Class ;
    rdfs:label "sample collection or study aim description"@en ;
    rdfs:subClassOf obo:IAO_0000300 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000300
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:unionOf ([
                            a owl:Class ;
                            owl:intersectionOf (obo:BFO_0000027
                                [
                                    a owl:Restriction ;
                                    owl:allValuesFrom obo:OBI_0100051 ;
                                    owl:onProperty obo:BFO_0000051
                                ]
                            )
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:IAO_0000136 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:IAO_0000005
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:BFO_0000050 ;
                                        owl:someValuesFrom obo:OBI_0500000
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000649
    obo:IAO_0000115 "A proper name that designates a study."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Study name"@en ;
    a owl:Class ;
    rdfs:label "study proper name"@en ;
    rdfs:subClassOf obo:IAO_0020000 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0020000
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0020012 ;
                owl:someValuesFrom obo:OBI_0000471
            ]
        )
    ] .

obo:OBIB_0000650
    obo:IAO_0000115 "A personal name that designates the human being responsible for a sample collection or the human being being the principal investigator in a study."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection Responsible / Principal Investigator"@en ;
    a owl:Class ;
    rdfs:label "name of sample collection responsible or principal investigator"@en ;
    rdfs:subClassOf obo:IAO_0020015 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0020012 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:NCBITaxon_9606
                [
                    a owl:Class ;
                    owl:unionOf ([
                            a owl:Class ;
                            owl:intersectionOf ([
                                    a owl:Restriction ;
                                    owl:onProperty obo:BFO_0000050 ;
                                    owl:someValuesFrom [
                                        a owl:Class ;
                                        owl:intersectionOf (obo:BFO_0000027
                                            [
                                                a owl:Restriction ;
                                                owl:onProperty obo:OBIB_0000733 ;
                                                owl:someValuesFrom [
                                                    a owl:Class ;
                                                    owl:intersectionOf (obo:BFO_0000027
                                                        [
                                                            a owl:Restriction ;
                                                            owl:allValuesFrom obo:OBI_0100051 ;
                                                            owl:onProperty obo:BFO_0000051
                                                        ]
                                                    )
                                                ]
                                            ]
                                        )
                                    ]
                                ]
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:RO_0000053 ;
                                    owl:someValuesFrom obo:OBI_0000102
                                ]
                            )
                        ]
                        [
                            a owl:Class ;
                            owl:intersectionOf ([
                                    a owl:Restriction ;
                                    owl:onProperty obo:RO_0000053 ;
                                    owl:someValuesFrom obo:OBI_0000103
                                ]
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:RO_0000056 ;
                                    owl:someValuesFrom obo:OBI_0000471
                                ]
                            )
                        ]
                    )
                ]
            )
        ]
    ] .

obo:OBIB_0000651
    obo:IAO_0000115 "A personal name that designates the person acting as contact for a sample collection or a study."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection/Study contact person"@en ;
    a owl:Class ;
    rdfs:label "name of sample collection or study contact person"@en ;
    rdfs:subClassOf obo:IAO_0020015 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0020012 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:NCBITaxon_9606
                [
                    a owl:Class ;
                    owl:unionOf ([
                            a owl:Class ;
                            owl:intersectionOf ([
                                    a owl:Restriction ;
                                    owl:onProperty obo:BFO_0000050 ;
                                    owl:someValuesFrom [
                                        a owl:Class ;
                                        owl:intersectionOf (obo:BFO_0000027
                                            [
                                                a owl:Restriction ;
                                                owl:onProperty obo:OBIB_0000733 ;
                                                owl:someValuesFrom [
                                                    a owl:Class ;
                                                    owl:intersectionOf (obo:BFO_0000027
                                                        [
                                                            a owl:Restriction ;
                                                            owl:allValuesFrom obo:OBI_0100051 ;
                                                            owl:onProperty obo:BFO_0000051
                                                        ]
                                                    )
                                                ]
                                            ]
                                        )
                                    ]
                                ]
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:RO_0000053 ;
                                    owl:someValuesFrom obo:OBIB_0000670
                                ]
                            )
                        ]
                        [
                            a owl:Class ;
                            owl:intersectionOf ([
                                    a owl:Restriction ;
                                    owl:onProperty obo:RO_0000053 ;
                                    owl:someValuesFrom obo:OBIB_0000670
                                ]
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:RO_0000056 ;
                                    owl:someValuesFrom obo:OBI_0000471
                                ]
                            )
                        ]
                    )
                ]
            )
        ]
    ] .

obo:OBIB_0000652
    obo:IAO_0000115 "A department that has a contact person for a sample collection or a study as an organizational member."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection/Study contact department"@en ;
    a owl:Class ;
    rdfs:label "department of sample collection or study contact"@en ;
    rdfs:subClassOf obo:OBIB_0000630 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000630
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0001688 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:NCBITaxon_9606
                        [
                            a owl:Class ;
                            owl:unionOf ([
                                    a owl:Class ;
                                    owl:intersectionOf ([
                                            a owl:Restriction ;
                                            owl:onProperty obo:BFO_0000050 ;
                                            owl:someValuesFrom [
                                                a owl:Class ;
                                                owl:intersectionOf (obo:BFO_0000027
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:OBIB_0000733 ;
                                                        owl:someValuesFrom [
                                                            a owl:Class ;
                                                            owl:intersectionOf (obo:BFO_0000027
                                                                [
                                                                    a owl:Restriction ;
                                                                    owl:allValuesFrom obo:OBI_0100051 ;
                                                                    owl:onProperty obo:BFO_0000051
                                                                ]
                                                            )
                                                        ]
                                                    ]
                                                )
                                            ]
                                        ]
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:RO_0000053 ;
                                            owl:someValuesFrom obo:OBIB_0000670
                                        ]
                                    )
                                ]
                                [
                                    a owl:Class ;
                                    owl:intersectionOf ([
                                            a owl:Restriction ;
                                            owl:onProperty obo:RO_0000053 ;
                                            owl:someValuesFrom obo:OBIB_0000670
                                        ]
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:RO_0000056 ;
                                            owl:someValuesFrom obo:OBI_0000471
                                        ]
                                    )
                                ]
                            )
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000653
    obo:IAO_0000115 "A street is a  thoroughfare in a built environment."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "street"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:OBIB_0000654
    obo:IAO_0000115 "An intra-settlement specification part of address that is part of a sample collection or study contact's postal address."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection/Study contact address"@en ;
    a owl:Class ;
    rdfs:label "intra-settlement specification part of address of sample collection or study contact"@en ;
    rdfs:subClassOf obo:OBIB_0000643 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000643
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000422
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBIB_0000734 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:NCBITaxon_9606
                                    [
                                        a owl:Class ;
                                        owl:unionOf ([
                                                a owl:Class ;
                                                owl:intersectionOf ([
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:BFO_0000050 ;
                                                        owl:someValuesFrom obo:BFO_0000027
                                                    ]
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:OBIB_0000733 ;
                                                        owl:someValuesFrom [
                                                            a owl:Class ;
                                                            owl:intersectionOf (obo:BFO_0000027
                                                                [
                                                                    a owl:Restriction ;
                                                                    owl:allValuesFrom obo:OBI_0100051 ;
                                                                    owl:onProperty obo:BFO_0000051
                                                                ]
                                                            )
                                                        ]
                                                    ]
                                                )
                                            ]
                                            [
                                                a owl:Class ;
                                                owl:intersectionOf ([
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:RO_0000053 ;
                                                        owl:someValuesFrom obo:OBIB_0000670
                                                    ]
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:RO_0000056 ;
                                                        owl:someValuesFrom obo:OBI_0000471
                                                    ]
                                                )
                                            ]
                                        )
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000655
    obo:IAO_0000115 "Postal code that is part of the address of a human being serving as sample collection or study contact."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Sample Collection/Study contact ZIP"@en ;
    a owl:Class ;
    rdfs:label "postal code for sample collection or study contact"@en ;
    rdfs:subClassOf obo:IAO_0000646 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000646
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000050 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:IAO_0000422
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBIB_0000734 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:NCBITaxon_9606
                                    [
                                        a owl:Class ;
                                        owl:unionOf ([
                                                a owl:Class ;
                                                owl:intersectionOf ([
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:BFO_0000050 ;
                                                        owl:someValuesFrom obo:BFO_0000027
                                                    ]
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:OBIB_0000733 ;
                                                        owl:someValuesFrom [
                                                            a owl:Class ;
                                                            owl:intersectionOf (obo:BFO_0000027
                                                                [
                                                                    a owl:Restriction ;
                                                                    owl:allValuesFrom obo:OBI_0100051 ;
                                                                    owl:onProperty obo:BFO_0000051
                                                                ]
                                                            )
                                                        ]
                                                    ]
                                                )
                                            ]
                                            [
                                                a owl:Class ;
                                                owl:intersectionOf ([
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:RO_0000053 ;
                                                        owl:someValuesFrom obo:OBIB_0000670
                                                    ]
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:RO_0000056 ;
                                                        owl:someValuesFrom obo:OBI_0000471
                                                    ]
                                                )
                                            ]
                                        )
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000656
    obo:IAO_0000115 "An ISO 3166-1 alpha-2 code that designates the country a biobank is located in."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000118 "Biobank country code"@en ;
    a owl:Class ;
    rdfs:label "biobank location ISO 3166-1 alpha-2 code"@en ;
    rdfs:subClassOf obo:OBIB_0000620 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000620
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0020012 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:GAZ_00000448
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0001015 ;
                            owl:someValuesFrom obo:OBIB_0000616
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000657
    obo:IAO_0000115 "An identifier for an organization that is assigned to that organization by the Cancer Therapy Evaluation Program."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "CTEP organization identifier"@en ;
    rdfs:subClassOf obo:IAO_0020000, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0020012 ;
        owl:someValuesFrom obo:OBI_0000245
    ] .

obo:OBIB_0000658
    obo:IAO_0000115 "A biobank identifier that has both an ISO 3166-1 alpha-2 code and a CTEP organization code."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:Class ;
    rdfs:label "biobank identifier with ISO 3166-1 alpha-2 code and CTEP organization identifier"@en ;
    rdfs:subClassOf obo:OBIB_0000621, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBIB_0000620
                        [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBIB_0000657
                                [
                                    a owl:Restriction ;
                                    owl:allValuesFrom obo:OBIB_0000623 ;
                                    owl:onProperty obo:IAO_0020012
                                ]
                            )
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0020012 ;
                owl:someValuesFrom obo:OBIB_0000616
            ]
        )
    ] .

obo:OBIB_0000659
    obo:IAO_0000115 "A processed specimen that is the output of a fixation process."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "fixed tissue specimen"@en ;
    rdfs:subClassOf obo:OBI_0000953, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBIB_0000676
    ] .

obo:OBIB_0000660
    obo:IAO_0000115 "A fixed tissue specimen that is in block form."@en ;
    a owl:Class ;
    rdfs:label "fixed tissue block specimen"@en ;
    rdfs:subClassOf obo:OBIB_0000659 .

obo:OBIB_0000661
    obo:IAO_0000115 "A fixed tissue specimen that is placed in a slide."@en ;
    a owl:Class ;
    rdfs:label "fixed tissue slide specimen"@en ;
    rdfs:subClassOf obo:OBIB_0000659 .

obo:OBIB_0000662
    obo:IAO_0000115 "A frozen specimen that has been instantly/quickly frozen by subjecting the specimen to cryogenic temperatures, or in direct contact with liquid nitrogen at -320.8F 0r -196C."@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Flash_freezing"@en ;
    a owl:Class ;
    rdfs:label "flash frozen specimen"@en ;
    rdfs:subClassOf obo:OBI_0000922 .

obo:OBIB_0000663
    obo:IAO_0000115 "A fresh specimen that is in a tissue form."@en ;
    a owl:Class ;
    rdfs:label "fresh tissue specimen"@en ;
    rdfs:subClassOf obo:OBI_0000971 .

obo:OBIB_0000664
    obo:IAO_0000115 "A frozen specimen is a tissue sample preserved in a block."@en ;
    a owl:Class ;
    rdfs:label "frozen tissue block specimen"@en ;
    rdfs:subClassOf obo:OBI_0000922 .

obo:OBIB_0000665
    obo:IAO_0000115 "A frozen specimen that has been sliced from a tissue block into thin layers that are placed on a glass to be examined under a microscope."@en ;
    a owl:Class ;
    rdfs:label "frozen tissue slide specimen"@en ;
    rdfs:subClassOf obo:OBI_0000922 .

obo:OBIB_0000666
    obo:IAO_0000115 "A specimen that has been procured from a histology slide under direct microscopic visualization."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    obo:IAO_0000119 "http://www.ncbi.nlm.nih.gov/pubmed/11269646"@en ;
    a owl:Class ;
    rdfs:label "microdissected specimen"@en ;
    rdfs:subClassOf obo:OBI_0100051 .

obo:OBIB_0000667
    obo:IAO_0000115 "A data item that contains the outcome of a survey."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "survey data"@en ;
    rdfs:subClassOf obo:IAO_0000027 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:OBIB_0000710 ;
                owl:onProperty obo:OBI_0000312
            ]
        )
    ] .

obo:OBIB_0000668
    obo:IAO_0000115 "The process of collecting or selecting an aggregate of specimens into a biobank."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "sampling specimens for biobank"@en ;
    rdfs:subClassOf obo:OBI_0000011 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000011
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000299 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000027
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000050 ;
                            owl:someValuesFrom obo:OBIB_0000616
                        ]
                        [
                            a owl:Restriction ;
                            owl:allValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:OBI_0100051
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:RO_0000056 ;
                                        owl:someValuesFrom obo:OBI_0302893
                                    ]
                                )
                            ] ;
                            owl:onProperty obo:BFO_0000051
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000669
    obo:IAO_0000115 "A contact role borne by a member of a biobank organization and realized by serving as the contact for one of its biobanks."@en ;
    a owl:Class ;
    rdfs:label "biobank contact role"@en ;
    rdfs:subClassOf obo:OBIB_0000625 .

obo:OBIB_0000670
    obo:IAO_0000115 "A contact role borne by a member of a sample collection or study organization and realized by serving as the contact for the collection or the study."@en ;
    a owl:Class ;
    rdfs:label "sample collection or study contact role"@en ;
    rdfs:subClassOf obo:OBIB_0000625 .

obo:OBIB_0000671
    obo:IAO_0000115 "A human being acting as bearing the contact role for a sample collection or a study." ;
    a owl:Class ;
    rdfs:label "sample collection or study contact person"@en ;
    rdfs:subClassOf obo:NCBITaxon_9606 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:NCBITaxon_9606
            [
                a owl:Class ;
                owl:unionOf ([
                        a owl:Class ;
                        owl:intersectionOf ([
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000050 ;
                                owl:someValuesFrom [
                                    a owl:Class ;
                                    owl:intersectionOf (obo:BFO_0000027
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:OBIB_0000733 ;
                                            owl:someValuesFrom [
                                                a owl:Class ;
                                                owl:intersectionOf (obo:BFO_0000027
                                                    [
                                                        a owl:Restriction ;
                                                        owl:allValuesFrom obo:OBI_0100051 ;
                                                        owl:onProperty obo:BFO_0000051
                                                    ]
                                                )
                                            ]
                                        ]
                                    )
                                ]
                            ]
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000053 ;
                                owl:someValuesFrom obo:OBIB_0000670
                            ]
                        )
                    ]
                    [
                        a owl:Class ;
                        owl:intersectionOf ([
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000053 ;
                                owl:someValuesFrom obo:OBIB_0000670
                            ]
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000056 ;
                                owl:someValuesFrom obo:OBI_0000471
                            ]
                        )
                    ]
                )
            ]
        )
    ] .

obo:OBIB_0000672
    obo:IAO_0000115 "A data item that indicates the pathological assessment of a specimen."@en ;
    a owl:Class ;
    rdfs:label "specimen disease state datum"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom obo:OBI_0100051
    ] .

obo:OBIB_0000673
    obo:IAO_0000115 "A specimen disease state datum item that specifies that the specimen in question consists of a disorder."@en ;
    a owl:Class ;
    rdfs:label "diseased state specimen datum"@en ;
    rdfs:subClassOf obo:OBIB_0000672, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0100051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000051 ;
                    owl:someValuesFrom obo:OGMS_0000045
                ]
            )
        ]
    ] .

obo:OBIB_0000674
    obo:IAO_0000115 "A specimen disease state datum that specifies that the specimen in question consists of partially normal tissue and a disorder."@en ;
    a owl:Class ;
    rdfs:label "mixed state specimen datum"@en ;
    rdfs:subClassOf obo:OBIB_0000672, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0100051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000051 ;
                    owl:someValuesFrom obo:OBIB_0000726
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000051 ;
                    owl:someValuesFrom obo:OGMS_0000045
                ]
            )
        ]
    ] .

obo:OBIB_0000675
    obo:IAO_0000115 "A specimen disease state datum that specifies that the specimenin questions consists of normal tissue."@en ;
    a owl:Class ;
    rdfs:label "normal state specimen datum"@en ;
    rdfs:subClassOf obo:OBIB_0000672, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom obo:OBIB_0000726
    ] .

obo:OBIB_0000676
    obo:IAO_0000115 "A material processing that uses chemical process by which biological tissues are preserved from decay. Fixation terminates any ongoing biochemical reactions and may increase stability of the treated tissues."@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Fixation_%28histology%29"@en, "http://sharedresources.fhcrc.org/training/tips-about-fixation-and-formalin"@en ;
    a owl:Class ;
    rdfs:comment "The choice of fixation depends on the type of study."@en ;
    rdfs:label "fixation"@en ;
    rdfs:subClassOf obo:OBI_0000094 .

obo:OBIB_0000677
    obo:IAO_0000115 "An information content entity that is about a data set that has age information and specifies the range of age information in that data set."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Martin Fransson"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:comment "Example: age interval is 18-65"@en ;
    rdfs:label "age interval information"@en ;
    rdfs:subClassOf obo:IAO_0000030, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000030
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf ([
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000050 ;
                            owl:someValuesFrom obo:IAO_0000100
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:IAO_0000136 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:BFO_0000038
                                    [
                                        a owl:Restriction ;
                                        owl:onClass obo:BFO_0000182 ;
                                        owl:onProperty obo:BFO_0000156 ;
                                        owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000678
    obo:IAO_0000115 "An average value of age for a certain group of individuals."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "average age"@en ;
    rdfs:subClassOf obo:OBI_0000679, [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000679
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf ([
                            a owl:Class ;
                            owl:intersectionOf (obo:IAO_0000109
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:IAO_0000136 ;
                                    owl:someValuesFrom [
                                        a owl:Class ;
                                        owl:intersectionOf (obo:BFO_0000038
                                            [
                                                a owl:Restriction ;
                                                owl:onClass obo:BFO_0000182 ;
                                                owl:onProperty obo:BFO_0000156 ;
                                                owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger
                                            ]
                                        )
                                    ]
                                ]
                            )
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000050 ;
                            owl:someValuesFrom obo:IAO_0000100
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000679
    obo:IAO_0000115 "A data set of collected secondary data related to patients with a specific diagnosis, condition, or procedure and plays an important role in post marketing surveillance of pharmaceuticals."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Martin Fransson"@en ;
    obo:IAO_0000118 "patient register data"@en ;
    a owl:Class ;
    rdfs:comment "It can be said to be a formal record of an internationally agreed minimum amount of information about clinical trial."@en ;
    rdfs:label "patient registry data"@en ;
    rdfs:subClassOf obo:IAO_0000100, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom obo:NCBITaxon_9606
    ] .

obo:OBIB_0000680
    obo:IAO_0000115 "A data item that indicates the time when data about the sample collection was reported into a database."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:comment "It is denoted by Date in ISO-standard (8601) time format."@en ;
    rdfs:label "date of data entry"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000038
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000051 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:BFO_0000038
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:BFO_0000156 ;
                                        owl:someValuesFrom obo:OBIB_0000708
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] ;
    owl:disjointWith obo:OBIB_0000681, obo:OBIB_0000682, obo:OBIB_0000683 .

obo:OBIB_0000681
    obo:IAO_0000115 "A data item that indicates the time when data about the sample collection was last updated in a database."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:comment "It is expressed as a Date in ISO-standard (8601) time format."@en ;
    rdfs:label "date of data update"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000038
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000051 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:BFO_0000038
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:BFO_0000156 ;
                                        owl:someValuesFrom obo:OBIB_0000709
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] ;
    owl:disjointWith obo:OBIB_0000682, obo:OBIB_0000683 .

obo:OBIB_0000682
    obo:IAO_0000115 "A data item that indicates the time when the sampling of specimens for a biobank ended."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:comment "It is denoted by Date in ISO-standard (8601) time format."@en ;
    rdfs:label "end date of sampling for biobank"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000038
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000051 ;
                            owl:someValuesFrom [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000156 ;
                                owl:someValuesFrom obo:OBIB_0000731
                            ]
                        ]
                    )
                ]
            ]
        )
    ] ;
    owl:disjointWith obo:OBIB_0000683 .

obo:OBIB_0000683
    obo:IAO_0000115 "A data item that indicates the time when the sampling of specimens for a biobank started."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:comment "It is denoted by Date in ISO-standard (8601) time format."@en ;
    rdfs:label "start date of sampling for biobank"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000038
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000051 ;
                            owl:someValuesFrom [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000156 ;
                                owl:someValuesFrom obo:OBIB_0000730
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000684
    obo:IAO_0000115 "A diagnosis that is the outcome of a diagnostic process targeting a second or additional health problem."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    obo:IAO_0000118 "secondary infection, nosocomial infection"@en ;
    obo:IAO_0000119 "amended from http://en.wikipedia.org/wiki/Comorbidity"@en ;
    a owl:Class ;
    rdfs:comment "It is argued that Comorbidity occurs due to a disposition established by a prior infection with a pathogenic organism of a different kind."@en ;
    rdfs:label "comorbidity"@en ;
    rdfs:subClassOf obo:OGMS_0000073 ;
    owl:disjointWith obo:OBIB_0000685 .

obo:OBIB_0000685
    obo:IAO_0000115 "A diagnosis that is the main reason for the inducement of medical care."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    obo:IAO_0000118 "main diagnosis"@en ;
    obo:IAO_0000119 """Hint:
http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf"""@en ;
    a owl:Class ;
    rdfs:label "primary diagnosis"@en ;
    rdfs:subClassOf obo:OGMS_0000073 .

obo:OBIB_0000686
    obo:IAO_0000115 "A count that is about the aggregate of individuals who have contributed biological specimens in a study."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "count of current sampled human study participant"@en ;
    rdfs:subClassOf obo:APOLLO_SV_00000032, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000027
                [
                    a owl:Restriction ;
                    owl:allValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:NCBITaxon_9606
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000053 ;
                                owl:someValuesFrom obo:OBI_0000097
                            ]
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000056 ;
                                owl:someValuesFrom [
                                    a owl:Class ;
                                    owl:intersectionOf (obo:OBI_0000659
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:BFO_0000050 ;
                                            owl:someValuesFrom obo:OBI_0000471
                                        ]
                                    )
                                ]
                            ]
                        )
                    ] ;
                    owl:onProperty obo:BFO_0000051
                ]
            )
        ]
    ] ;
    owl:disjointWith obo:OBIB_0000688 .

obo:OBIB_0000687
    obo:IAO_0000115 "A count that is about the aggregate of individuals who have been recruited to participate in a study."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "count of current total human study participant"@en ;
    rdfs:subClassOf obo:APOLLO_SV_00000032, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000027
                [
                    a owl:Restriction ;
                    owl:allValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:NCBITaxon_9606
                            [
                                a owl:Class ;
                                owl:intersectionOf ([
                                        a owl:Restriction ;
                                        owl:onProperty obo:RO_0000053 ;
                                        owl:someValuesFrom obo:OBI_0000097
                                    ]
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:RO_0000056 ;
                                        owl:someValuesFrom obo:OBI_0000471
                                    ]
                                )
                            ]
                        )
                    ] ;
                    owl:onProperty obo:BFO_0000051
                ]
            )
        ]
    ] ;
    owl:disjointWith obo:OBIB_0000688 .

obo:OBIB_0000688
    obo:IAO_0000115 "A measurement datum that contains the assessment information about the functioning of a major organ system, the extent of disease or disability,as well as the provision and/or response to therapeutic interventions."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    obo:IAO_0000119 "http://www.improvement.nhs.uk/physiologydiagnostics/documents/WhatisPhysiologicalMeasurement.pdf" ;
    a owl:Class ;
    rdfs:comment "Examples: Audiology, Cardiac Physiology, GI Physiology, Neurophysiology, Ophthalmic and Vision Science, Respiratory and Sleep Physiology, Urodynamics, Vascular Technology"@en ;
    rdfs:label "physiological measurement data"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:unionOf (obo:OGMS_0000031
                        obo:OGMS_0000045
                        obo:OGMS_0000090
                        [
                            a owl:Class ;
                            owl:intersectionOf (obo:BFO_0000034
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:RO_0000052 ;
                                    owl:someValuesFrom [
                                        a owl:Restriction ;
                                        owl:onProperty obo:BFO_0000050 ;
                                        owl:someValuesFrom obo:OBI_0100026
                                    ]
                                ]
                            )
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000689
    obo:IAO_0000115 "A setting datum that specifies the temperature inside a container participating in a storage process."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:comment "Examples:  -18 °C to -35 °C, -60 °C to -85 °C, Liquid nitrogen, Room temperature etc"@en ;
    rdfs:label "storage temperature setting"@en ;
    rdfs:subClassOf obo:IAO_0000140 .

obo:OBIB_0000690
    obo:IAO_0000115 "An objective specification that aims at the collective characterization and quantification of pools of biological molecules that translate into the structure, function, and dynamics of an organism or organisms."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Omics"@en ;
    a owl:Class ;
    rdfs:comment "A tentative procedure that is aimed at discovering some characteristic of a large familiy of cellular molecules, having named by appending suffix \"-omics.\""@en, "Technologies that measure some characteristic of a large family of cellular molecules, such as genes, proteins, or small metabolites, have been named by appending the suffix \"-omics,\" as in \"genomics.\" Omics refers to the collective technologies used to explore the roles, relationships, and actions of the various types of molecules that make up the cells of an organism."@en, "interrelated experiments."@en ;
    rdfs:label "omics experiment on specimen"@en ;
    rdfs:subClassOf obo:OBI_0000471, [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000011
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000059 ;
                    owl:someValuesFrom obo:OBI_0500000
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000057 ;
                owl:someValuesFrom obo:OBI_0100051
            ]
        )
    ] .

obo:OBIB_0000691
    obo:IAO_0000115 "An objective specification that specifies the number of individuals to participate in a study and provide biological specimens to the study."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "number of sampled human study participants objective"@en ;
    rdfs:subClassOf obo:IAO_0000005, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000050 ;
        owl:someValuesFrom obo:OBI_0500000
    ] ;
    owl:disjointWith obo:OBIB_0000692 .

obo:OBIB_0000692
    obo:IAO_0000115 "An objective specification that specifies the total number of individuals who are planned to participate in study."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "number of total human study participant objective"@en ;
    rdfs:subClassOf obo:IAO_0000005, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000050 ;
        owl:someValuesFrom obo:OBI_0500000
    ] .

obo:OBIB_0000693
    obo:IAO_0000115 "A study design that compares two groups of subjects; those with the disease or condtion under study and a similar group of subjects who do not have the condition."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "case control study design"@en ;
    rdfs:subClassOf obo:OBI_0500000 ;
    owl:disjointWith obo:OBIB_0000694, obo:OBIB_0000695, obo:OBIB_0000698, obo:OBIB_0000699, obo:OBIB_0000700 .

obo:OBIB_0000694
    obo:IAO_0000115 "A study design in which all participants or a representative subset of participants are examined at only a single time for characteristics of a interest (e.g. a specific disease)."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "cross sectional study design"@en ;
    rdfs:subClassOf obo:OBI_0500000 ;
    owl:disjointWith obo:OBIB_0000695, obo:OBIB_0000698, obo:OBIB_0000699, obo:OBIB_0000700 .

obo:OBIB_0000695
    obo:IAO_0000115 "A study design that involves repeated observations of the same entity over time. In the biobank context, longitudinal studies sample a group of people in a given time period, and study them at intervals by the acquisition and analyses of data and/or samples over time."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "longitudinal study design"@en ;
    rdfs:subClassOf obo:OBI_0500000 ;
    owl:disjointWith obo:OBIB_0000698, obo:OBIB_0000699, obo:OBIB_0000700 .

obo:OBIB_0000696
    obo:IAO_0000115 "A longitudinal study that aims to study a case-defined population who presently have a certain condition or recepient of a particular treatment that are followed over time and are compared with a similar group who do not have condition."@en ;
    a owl:Class ;
    rdfs:label "cohort study design"@en ;
    rdfs:subClassOf obo:OBIB_0000695 ;
    owl:disjointWith obo:OBIB_0000697 .

obo:OBIB_0000697
    obo:IAO_0000115 "A longitudinal study that samples a cross-section and studies it at regular intervals."@en ;
    a owl:Class ;
    rdfs:label "panel study design"@en ;
    rdfs:subClassOf obo:OBIB_0000695 .

obo:OBIB_0000698
    obo:IAO_0000115 "A study design that is multidisciplinary done at the population level or among the population groups, generally to find the cause, incidence or spread of the disease or to see the response to the treatment, nutrition or environment."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "population based study design"@en ;
    rdfs:subClassOf obo:OBI_0500000 ;
    owl:disjointWith obo:OBIB_0000699, obo:OBIB_0000700 .

obo:OBIB_0000699
    obo:IAO_0000115 "A study design where some aspect of the experiment is quality controlled for the purposes of quality assurance."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "quality control study design"@en ;
    rdfs:subClassOf obo:OBI_0500000 ;
    owl:disjointWith obo:OBIB_0000700 .

obo:OBIB_0000700
    obo:IAO_0000115 "A study design usually in behavior genetics which aids the study of individual differences between genetically identical twins by highlighting the role of environmental and genetic causes on behavior."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "twin study design"@en ;
    rdfs:subClassOf obo:OBI_0500000 .

obo:OBIB_0000701
    obo:IAO_0000115 "A plan specification that is realized by  process of gathering information (e.g. by asking questions)."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "survey plan specification"@en ;
    rdfs:subClassOf obo:IAO_0000104 .

obo:OBIB_0000702
    obo:IAO_0000115 "A document that contains information representing health-relevant qualities of a patient written in a chronological manner and that is primarily used for patient care in a clinical setting."@en ;
    obo:IAO_0000117 "Martin Fransson" ;
    a owl:Class ;
    rdfs:comment "It is a chronological written account of examination, treatment, medical history or complaints.", """It is used interchangeably with health record and medical chart.
https://en.wikipedia.org/wiki/Medical_record""" ;
    rdfs:label "medical record"@en ;
    rdfs:subClassOf obo:IAO_0000310 .

obo:OBIB_0000703
    obo:IAO_0000115 "A medical record of a specimen donor."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "sample medical record"@en ;
    rdfs:subClassOf obo:OBIB_0000702, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:NCBITaxon_9606
                [
                    a owl:Class ;
                    owl:intersectionOf ([
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000087 ;
                            owl:someValuesFrom obo:OBI_0000097
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000087 ;
                            owl:someValuesFrom obo:OBI_1110087
                        ]
                    )
                ]
            )
        ]
    ] .

obo:OBIB_0000704
    obo:IAO_0000115 "A document that outlines the procedures employed to preserve and protect the material collected during specimen collection as an indication of sample quality."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:comment "It could be argued as to why this class was not created as an 'objective specification'. However, the emphasis here is to 'a briefing of how the specimen in the sample collection have been handled as an indication of specimen quality.'"@en, "It could be freeze chain, freze time, SPREC compliant, etc."@en ;
    rdfs:label "sample handling summary"@en ;
    rdfs:subClassOf obo:IAO_0000310 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom obo:OBIB_0000729
    ] .

obo:OBIB_0000705
    obo:IAO_0000115 "Age interval information that is age information of specimen donors."@en ;
    obo:IAO_0000117 "Alice Nzinga" ;
    obo:IAO_0000118 "sampled group age interval"@en ;
    obo:IAO_0000119 "http://www.abta.org/Dictionary/67"@en ;
    a owl:Class ;
    rdfs:label "age interval information for sampled donors"@en ;
    rdfs:subClassOf obo:OBIB_0000677, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000030
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000050 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:IAO_0000100
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:IAO_0000136 ;
                                owl:someValuesFrom [
                                    a owl:Class ;
                                    owl:intersectionOf (obo:BFO_0000038
                                        [
                                            a owl:Restriction ;
                                            owl:onClass [
                                                a owl:Class ;
                                                owl:intersectionOf (obo:BFO_0000182
                                                    [
                                                        a owl:Restriction ;
                                                        owl:onProperty obo:BFO_0000184 ;
                                                        owl:someValuesFrom obo:OBIB_0000728
                                                    ]
                                                )
                                            ] ;
                                            owl:onProperty obo:BFO_0000156 ;
                                            owl:qualifiedCardinality "1"^^xsd:nonNegativeInteger
                                        ]
                                    )
                                ]
                            ]
                        )
                    ]
                ]
            ]
        )
    ] .

obo:OBIB_0000706
    obo:IAO_0000115 "Registry data for a patient who participates as a donor in a study."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "donor patient registry data"@en ;
    rdfs:subClassOf obo:OBIB_0000679, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom obo:OBI_1110087
    ] .

obo:OBIB_0000707
    obo:IAO_0000115 "A survey data for a specimen donor."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:comment "Examples: Individual Disease History, Individual History of Injuries, Medication, Perception of Health, Women's Health, Reproductive History, Familial Disease History, Life Habits/Behaviors, Sociodemographic Characteristics, Socioeconomic Characteristics, Physical Environment, Mental Health, Other."@en ;
    rdfs:label "study subject survey data"@en ;
    rdfs:subClassOf obo:OBIB_0000667, [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000667
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf ([
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000053 ;
                            owl:someValuesFrom obo:OBI_0000097
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000053 ;
                            owl:someValuesFrom obo:OBI_1110087
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000708
    obo:IAO_0000115 "A planned process that involves the initial entering of data about sample collection into a database."@en ;
    a owl:Class ;
    rdfs:label "sample collection data entry"@en ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000709
    obo:IAO_0000115 "A planned process which involves editing of specimen collection data into a database after its initial entry."@en ;
    a owl:Class ;
    rdfs:label "sample collection data update"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBIB_0000681
    ] .

obo:OBIB_0000710
    obo:IAO_0000115 "A planned process that realizes the concretization of a survey to generate an output(survey data.)"@en ;
    a owl:Class ;
    rdfs:label "survey execution"@en ;
    rdfs:subClassOf obo:OBI_0000011 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000011
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000059 ;
                    owl:someValuesFrom obo:OBIB_0000701
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000299 ;
                owl:someValuesFrom obo:OBIB_0000667
            ]
        )
    ] .

obo:OBIB_0000711
    obo:IAO_0000115 "A planned process that aims to control or maintain the temperature of a material entity to a given or required measurement datum." ;
    a owl:Class ;
    rdfs:comment "As per placing the term as a planned process, it can be argued that nature does play a role in the final output of the actual temperature." ;
    rdfs:label "temperature regulating"@en ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000712
    obo:IAO_0000115 "A textual entity that states additional information about the specimen or donor that is deemed relevant for the specimen collection process."@en ;
    obo:IAO_0000119 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "comment from tissue procurement"@en ;
    rdfs:subClassOf obo:IAO_0000300, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:OBIB_0000668
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000056 ;
                    owl:someValuesFrom obo:OBIB_0000668
                ]
            )
        ]
    ] .

obo:OBIB_0000713
    obo:IAO_0000112 "3mm X 3mm X 3mm"@en ;
    obo:IAO_0000115 "A measurement datum that is the result of measurement of the three dimensions of a specimen."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "specimen measurement"@en ;
    rdfs:subClassOf obo:IAO_0000109, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000109
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom obo:IAO_0000408
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom obo:OBI_0100051
            ]
        )
    ] .

obo:OBIB_0000714
    obo:IAO_0000115 "A data item that indicates the time when the collection of a specimen occurred."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    obo:IAO_0000118 "date of specimen preparation"@en ;
    a owl:Class ;
    rdfs:comment "It is denoted by Date in ISO-standard (8601) time format."@en ;
    rdfs:label "date of specimen collection"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000038
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000051 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:BFO_0000038
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:BFO_0000156 ;
                                        owl:someValuesFrom obo:OBI_0000659
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000715
    obo:IAO_0000115 "All specimens that meet the set parameters to be procured on."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000118 "adherance to specification"@en ;
    a owl:Class ;
    rdfs:label "specimen meeting specification"@en ;
    rdfs:subClassOf obo:OBI_0100051 .

obo:OBIB_0000716
    obo:IAO_0000112 "mastectomy / craniotomy / liver resection e.t.c."@en ;
    obo:IAO_0000115 "A planned process that uses operative manual and instrumental techniques on a patient to investigate and/or treat a pathological condition such as disease or injury, or to help improve bodily function or appearance."@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Surgery"@en ;
    a owl:Class ;
    rdfs:label "surgical procedure"@en ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBIB_0000717
    obo:IAO_0000115 "A personal name that designates the person who prepared the specimen."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "specimen preparation contact"@en ;
    rdfs:subClassOf obo:IAO_0020015, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:NCBITaxon_9606
                [
                    a owl:Class ;
                    owl:unionOf ([
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000056 ;
                            owl:someValuesFrom obo:OBI_0000659
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000056 ;
                            owl:someValuesFrom obo:OBI_0000838
                        ]
                    )
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000053 ;
                    owl:someValuesFrom obo:OBIB_0000625
                ]
            )
        ]
    ] .

obo:OBIB_0000718
    obo:IAO_0000112 "15min"@en ;
    obo:IAO_0000115 "A time measurement datum that states the duration during which a specimen was submerged in formalin."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    a owl:Class ;
    rdfs:label "time in formalin measurement"@en ;
    rdfs:subClassOf obo:IAO_0000416, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf ([
                    a owl:Class ;
                    owl:unionOf (obo:BFO_0000038
                        obo:BFO_0000148
                    )
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000156 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:OBIB_0000729
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000057 ;
                                owl:someValuesFrom [
                                    a owl:Class ;
                                    owl:intersectionOf (obo:OBI_0100051
                                        [
                                            a owl:Restriction ;
                                            owl:onProperty obo:RO_0001025 ;
                                            owl:someValuesFrom obo:CHEBI_16842
                                        ]
                                    )
                                ]
                            ]
                        )
                    ]
                ]
            )
        ]
    ] .

obo:OBIB_0000719
    obo:IAO_0000115 "A collecting specimen from organism process that involves removing the specimen from an individual through a surgical procedure."@en ;
    a owl:Class ;
    rdfs:label "specimen surgical removal"@en ;
    rdfs:subClassOf obo:OBI_0600005 .

obo:OBIB_0000720
    obo:IAO_0000115 "A freezing storage for the specimen."@en ;
    a owl:Class ;
    rdfs:label "specimen freezing"@en ;
    rdfs:subClassOf obo:OBI_0000915 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000915
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000057 ;
                owl:someValuesFrom obo:OBI_0100051
            ]
        )
    ] .

obo:OBIB_0000721
    obo:IAO_0000115 "A proper name that identifies a specimen and is usually in form of a label included in the specimen cassette."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    obo:IAO_0000119 "http://biospecimens.cancer.gov/resources/sops/GTEx_SOPs/II/A/GTEx%20Tissue%20Procurement%20SOP%20%28PR-0004%20v1.2.1%29.pdf"@en ;
    a owl:Class ;
    rdfs:label "specimen ID"@en ;
    rdfs:subClassOf obo:IAO_0020000, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom obo:IAO_0000577
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom obo:OBI_0100051
            ]
        )
    ] .

obo:OBIB_0000722
    obo:IAO_0000115 "An identifier that refers to a specimen donor who is participating in specimen collection process for tissue procurement purposes and is usually assigned at the time of donor procurement."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    obo:IAO_0000119 "http://biospecimens.cancer.gov/resources/sops/GTEx_SOPs/II/A/GTEx%20Tissue%20Procurement%20SOP%20%28PR-0004%20v1.2.1%29.pdf"@en ;
    a owl:Class ;
    rdfs:label "case ID"@en ;
    rdfs:subClassOf obo:IAO_0020000, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:NCBITaxon_9606
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000056 ;
                    owl:someValuesFrom obo:OBI_0000659
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000087 ;
                    owl:someValuesFrom obo:OBI_1110087
                ]
            )
        ]
    ] .

obo:OBIB_0000723
    obo:IAO_0000115 "An directive information entity that states the technical standard measurement set and values that determines if a specimen qualifies for procurement or not."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Specification_(technical_standard)"@en ;
    a owl:Class ;
    rdfs:comment "A specification (often abbreviated as spec) may refer to an explicit set of requirements to be satisfied by a material, design, product, or service."@en ;
    rdfs:label "specimen measurement specification"@en ;
    rdfs:subClassOf obo:IAO_0000005 .

obo:OBIB_0000724
    obo:IAO_0000115 "A data item that reports the time when a specimen was frozen."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "time of specimen freezing"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000038
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000156 ;
                            owl:someValuesFrom obo:OBIB_0000720
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000725
    obo:IAO_0000115 "A data item that reports the time when a specimen was collected by a surgical procedure."@en ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "time of surgical removal of specimen"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000027
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000038
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000156 ;
                            owl:someValuesFrom obo:OBIB_0000719
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000726
    obo:IAO_0000115 "A specimen that is normal."@en ;
    a owl:Class ;
    rdfs:label "normal specimen"@en ;
    rdfs:subClassOf obo:OBI_0100051 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0100051
            [
                a owl:Class ;
                owl:complementOf [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000051 ;
                    owl:someValuesFrom obo:OGMS_0000045
                ]
            ]
        )
    ] .

obo:OBIB_0000727
    obo:IAO_0000115 "A biobank that collects and stores specimen during specimen collection primarily for the purposes of some study."@en ;
    obo:IAO_0000117 "Alice Nzinga" ;
    a owl:Class ;
    rdfs:label "hosting biobank"@en ;
    rdfs:subClassOf obo:OBIB_0000616 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000616
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000056 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000659
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000050 ;
                            owl:someValuesFrom obo:OBI_0000471
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000728
    obo:IAO_0000115 "A Homo sapiens who contributes specimen." ;
    obo:IAO_0000117 "Alice Nzinga"@en, "Mathias Brochhausen"@en ;
    obo:IAO_0000118 "sample donor"@en ;
    a owl:Class ;
    rdfs:label "specimen donor"@en ;
    rdfs:subClassOf obo:NCBITaxon_9606 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:NCBITaxon_9606
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000053 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000023
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000054 ;
                            owl:someValuesFrom obo:OBI_0000659
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBIB_0000729
    obo:IAO_0000115 "A planned process of preparing and submitting specimens to storage."@en ;
    obo:IAO_0000118 "specimen handling"@en ;
    obo:IAO_0000119 "http://www.exchangenetwork.net/standards/SampleHandling_01_06_2006_Final.pdf"@en ;
    a owl:Class ;
    rdfs:label "sample handling"@en ;
    rdfs:subClassOf obo:OBI_0000011 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000011
            [
                a owl:Class ;
                owl:intersectionOf ([
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000293 ;
                        owl:someValuesFrom [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000312 ;
                            owl:someValuesFrom obo:OBI_0000659
                        ]
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000299 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0100051
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:RO_0000056 ;
                                    owl:someValuesFrom obo:OBI_0302893
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBIB_0000730
    obo:IAO_0000115 "The process boundary marking the beginning of a sampling of specimens into a biobank."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "start of sampling specimens for biobank"@en ;
    rdfs:subClassOf obo:BFO_0000035, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000050 ;
        owl:someValuesFrom obo:OBIB_0000668
    ] .

obo:OBIB_0000731
    obo:IAO_0000115 "The process boundary marking the end of a sampling of specimens into a biobank."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    a owl:Class ;
    rdfs:label "end of sampling specimens for biobank"@en ;
    rdfs:subClassOf obo:BFO_0000035, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000050 ;
        owl:someValuesFrom obo:OBIB_0000668
    ] .

obo:OBIB_0000732
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000600 "This is a primitive relation. This relation is the foundation to the owners right to have the owned entity at his/her full disposal."@en ;
    dc:source "Reinach, A. Sämtliche Werke. Texkritische Ausgabe, München: Philosophia Verlag, 1989, p.189-204." ;
    a owl:AsymmetricProperty, owl:ObjectProperty ;
    rdfs:domain [
        a owl:Class ;
        owl:unionOf (obo:NCBITaxon_9606
            obo:OBI_0000245
            obo:OMRSE_00000023
            obo:OMRSE_00000033
        )
    ] ;
    rdfs:label "owns"@en ;
    rdfs:range [
        a owl:Class ;
        owl:unionOf (obo:BFO_0000040
            obo:IAO_0000030
        )
    ] ;
    rdfs:subPropertyOf owl:topObjectProperty ;
    owl:inverseOf obo:OBIB_0000735 .

obo:OBIB_0000733
    obo:IAO_0000115 "a administrates b if c owns b and some rights and obligations grounded in the owning relation regarding b are transferred  from c to a."@en ;
    obo:IAO_0000117 "Mathias Brochhausen", "Mathias Brochhausen"@en ;
    a owl:AsymmetricProperty, owl:ObjectProperty ;
    rdfs:comment "A definition of \"tranfers\" object property can be found in d-acts: http:purl.obolibrary.org/iao/d-acts.owl"@en ;
    rdfs:domain [
        a owl:Class ;
        owl:unionOf (obo:NCBITaxon_9606
            obo:OBI_0000245
            obo:OMRSE_00000023
            obo:OMRSE_00000033
        )
    ] ;
    rdfs:label "administrates"@en ;
    rdfs:range [
        a owl:Class ;
        owl:unionOf (obo:BFO_0000040
            obo:IAO_0000030
        )
    ] .

obo:OBIB_0000734
    obo:IAO_0000115 "a is contact information for b, if a is a information content entity, b is a human being or an organization and a identifies a physical location or electronic resource that allows to initiate communication with a."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    a owl:AsymmetricProperty, owl:IrreflexiveProperty, owl:ObjectProperty ;
    rdfs:domain obo:IAO_0000030 ;
    rdfs:label "is contact information about"@en ;
    rdfs:range [
        a owl:Class ;
        owl:unionOf (obo:NCBITaxon_9606
            obo:OBI_0000245
        )
    ] ;
    rdfs:subPropertyOf obo:IAO_0000136 .

obo:OBIB_0000735
    obo:IAO_0000115 "a is owned by b if b has complete power over a. All rights and obligations of ownership are grounded in this (primitive) relation. The claims and obligations of ownership can be partially transferred to a third party by the owner, b."@en ;
    obo:IAO_0000119 "Reinach, A. Sämtliche Werke. Texkritische Ausgabe, München: Philosophia Verlag, 1989, p.189-204." ;
    a owl:AsymmetricProperty, owl:ObjectProperty ;
    rdfs:domain [
        a owl:Class ;
        owl:unionOf (obo:BFO_0000040
            obo:IAO_0000030
        )
    ] ;
    rdfs:label "is owned by"@en ;
    rdfs:range [
        a owl:Class ;
        owl:unionOf (obo:NCBITaxon_9606
            obo:OBI_0000245
            obo:OMRSE_00000023
            obo:OMRSE_00000033
        )
    ] .

obo:OBIB_0002000
    obo:IAO_0000111 "specimen position" ;
    obo:IAO_0000112 "left side of specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A position inhering in a specimen." ;
    obo:IAO_0000116 "https://github.com/biobanking/biobanking/issues/24" ;
    obo:IAO_0000117 "Anna Maria Masci, Chris Stoeckert" ;
    obo:IAO_0000118 "specimen laterality" ;
    obo:IAO_0000119 "OBIB" ;
    a owl:Class ;
    rdfs:label "specimen position"@en ;
    rdfs:subClassOf obo:PATO_0000140 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:PATO_0000140
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:OBI_0100051 ;
                owl:onProperty obo:RO_0000052
            ]
        )
    ] .

obo:OBIB_0002001
    obo:IAO_0000111 "specimen integrity" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A wholeness that inheres in a specimen." ;
    obo:IAO_0000116 "https://github.com/biobanking/biobanking/issues/24" ;
    obo:IAO_0000117 "Anna Maria Masci, Chris Stoeckert" ;
    obo:IAO_0000119 "OBIB" ;
    a owl:Class ;
    rdfs:label "specimen integrity"@en ;
    rdfs:subClassOf obo:PATO_0001442 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:PATO_0001442
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:OBI_0100051 ;
                owl:onProperty obo:RO_0000052
            ]
        )
    ] .

obo:OBIB_0002002
    obo:IAO_0000111 "specimen weight" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A mass measurement datum that is the result of an assay to measure the weight of a specimen." ;
    obo:IAO_0000116 "https://github.com/biobanking/biobanking/issues/24" ;
    obo:IAO_0000117 "Anna Maria Masci, Chris Stoeckert" ;
    obo:IAO_0000119 "OBIB" ;
    a owl:Class ;
    rdfs:label "specimen weight"@en ;
    rdfs:subClassOf obo:IAO_0000414 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:IAO_0000414
            [
                a owl:Restriction ;
                owl:onProperty obo:IAO_0000136 ;
                owl:someValuesFrom obo:OBI_0100051
            ]
        )
    ] .

obo:OBIB_0002003
    obo:IAO_0000111 "specimen slide ID" ;
    obo:IAO_0000115 "An identifier that specifically identifies a particular specimen slide." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a owl:Class ;
    rdfs:label "specimen slide ID"@en ;
    rdfs:subClassOf obo:IAO_0020000 .

obo:OBIB_0002004
    obo:IAO_0000111 "surgical cancer treatment" ;
    obo:IAO_0000115 "A  cancer therapeutic procedure that involves a surgical procedure as a main part." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a owl:Class ;
    rdfs:label "surgical cancer treatment"@en ;
    rdfs:subClassOf obo:NCIT_C16212 .

obo:OBIB_0002005
    obo:IAO_0000111 "specimen gross appearance of metastatic tumor" ;
    obo:IAO_0000115 "A specimen gross appearance of a tumor that has spread from its original site by discontinuous (not direct) spread, e.g. by blood or lymphatics." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a owl:Class ;
    rdfs:label "specimen gross appearance of metastatic tumor"@en ;
    rdfs:subClassOf obo:OBIB_0000209 .

obo:OBIB_0002006
    obo:IAO_0000111 "specimen gross appearance of tumor center" ;
    obo:IAO_0000115 "A specimen gross appearance of the most internal topographic location of the tumor." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a owl:Class ;
    rdfs:label "specimen gross appearance of tumor center"@en ;
    rdfs:subClassOf obo:OBIB_0000209 .

obo:OBIB_0002007
    obo:IAO_0000111 "specimen gross appearance of tumor edge" ;
    obo:IAO_0000115 "A specimen gross appearance of the border of the tumor with non-tumorous tissue." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a owl:Class ;
    rdfs:label "specimen gross appearance of tumor edge"@en ;
    rdfs:subClassOf obo:OBIB_0000209 .

obo:OBIB_0002008
    obo:IAO_0000111 "research authorization for post mortem specimen donation for a specific tissue or fluid" ;
    obo:IAO_0000115 "A research authorization documentation for postmortem specimen donation in which the authorization is for a specified tissue or biological fluid." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a owl:Class ;
    rdfs:label "research authorization for post mortem specimen donation for a specific tissue or fluid"@en ;
    rdfs:subClassOf obo:OBIB_0000459 .

obo:OBIB_0002013
    obo:IAO_0000111 "tissue specimen suitability for molecular analysis" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A conclusion textual entity that signifies whether a specimen is acceptable for molecular analysis based on the assessment by a pathologist of a tissue specimen based on qualities such as purity and size." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a owl:Class ;
    rdfs:label "tissue specimen suitability for molecular analysis"@en ;
    rdfs:subClassOf obo:IAO_0000144 .

obo:OBI_0000011
    obo:IAO_0000111 "planned process"^^xsd:string, "planned process"@en ;
    obo:IAO_0000112 "Injecting mice with a vaccine in order to test its efficacy"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A process that realizes a plan which is the concretization of a plan specification."@en ;
    obo:IAO_0000116 "'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)"^^xsd:string, """We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some 
objectives is a planned process."""^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "branch derived"^^xsd:string ;
    obo:IAO_0000232 "6/11/9: Edited at workshop. Used to include: is initiated by an agent"^^xsd:string, "This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "planned process"@en ;
    rdfs:subClassOf obo:BFO_0000015 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000055 ;
        owl:someValuesFrom [
            a owl:Restriction ;
            owl:onProperty obo:RO_0000059 ;
            owl:someValuesFrom obo:IAO_0000104
        ]
    ] .

obo:OBI_0000014
    obo:IAO_0000111 "regulator role"^^xsd:string ;
    obo:IAO_0000112 "Fact sheet - Regulating the companies The role of the regulator. Ofwat is the economic regulator of the water and sewerage industry in England and Wales.  http://www.ofwat.gov.uk/aptrix/ofwat/publish.nsf/Content/roleofregulator_factsheet170805"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a regulatory role involved with making and/or enforcing relevant legislation and governmental orders"@en ;
    obo:IAO_0000117 "Person:Jennifer Fostel"@en ;
    obo:IAO_0000118 "regulator"^^xsd:string ;
    obo:IAO_0000119 "OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "regulator role"@en ;
    rdfs:subClassOf obo:OBI_0000017 .

obo:OBI_0000017
    obo:IAO_0000111 "regulatory role"@en ;
    obo:IAO_0000112 "Regulatory agency, Ethics committee, Approval letter; example:  Browse these EPA Regulatory Role subtopics  http://www.epa.gov/ebtpages/enviregulatoryrole.html  Feb 29, 2008"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body."@en ;
    obo:IAO_0000117 "GROUP:  Role branch"@en ;
    obo:IAO_0000119 "OBI, CDISC"@en ;
    obo:IAO_0000232 "govt agents responsible for creating regulations; proxies for enforcing regulations.  CDISC definition:  regulatory authorities. Bodies having the power to regulate. NOTE: In the ICH GCP guideline the term includes the authorities that review submitted clinical data and those that conduct inspections. These bodies are sometimes referred to as competent"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "regulatory role"@en ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0000018
    obo:IAO_0000111 "material supplier role"^^xsd:string ;
    obo:IAO_0000112 "Jackson Labs is an organization which provide mice as experimental material"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation."@en ;
    obo:IAO_0000116 "Supplier role is a special kind of service, e.g. biobank"^^xsd:string ;
    obo:IAO_0000117 "PERSON:Jennifer Fostel"@en ;
    obo:IAO_0000118 "material provider role"^^xsd:string, "supplier"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material supplier role"@en ;
    rdfs:subClassOf obo:OBI_0000947 .

obo:OBI_0000047
    obo:IAO_0000111 "processed material"@en ;
    obo:IAO_0000112 "Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "Is a material entity that is created or changed during material processing."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "processed material"@en ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom obo:OBI_0000094
            ]
        )
    ] .

obo:OBI_0000066
    obo:IAO_0000111 "investigation"@en ;
    obo:IAO_0000112 "Lung cancer investigation using expression profiling, a stem cell transplant investigation, biobanking is not an investigation, though it may be part of an investigation"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s)."@en ;
    obo:IAO_0000117 "Bjoern Peters"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000232 "Could add specific objective specification"^^xsd:string, """Following OBI call November 2012,26th: it was decided there was no need for adding \"achieves objective of drawing conclusion\" as existing relations were providing equivalent ability. this note closes the issue and validates the class definition to be part of the OBI core
editor = PRS"""@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    obo:OBI_0001847 "study"^^xsd:string ;
    a owl:Class ;
    rdfs:label "investigation"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:IAO_0000572
    ], [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:OBI_0000338
    ], [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:OBI_0000471
    ], [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0000339
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000299 ;
                    owl:someValuesFrom obo:OBI_0500000
                ]
            )
        ]
    ] .

obo:OBI_0000067
    obo:IAO_0000111 "evaluant role"@en ;
    obo:IAO_0000112 "When a specimen of blood is assayed for glucose concentration, the blood has the evaluant role. When measuring the mass of a mouse, the evaluant is the mouse. When measuring the time of DNA replication, the evaluant is the DNA. When measuring the intensity of light on a surface, the evaluant is the light source."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role"@en ;
    obo:IAO_0000116 "Role call - 17nov-08: JF and MC think an evaluant role is always specified input of a process. Even in the case where we have an assay taking blood as evaluant and outputting blood, the blood is not the specified output at the end of the assay (the concentration of glucose in the blood is)"@en, "examples of features that could be described in an evaluant: quality.... e.g. \"contains 10 pg/ml IL2\", or \"no glucose detected\")"@en ;
    obo:IAO_0000117 "GROUP:  Role Branch"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000232 "Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "evaluant role"@en ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0000070 ;
        owl:onProperty obo:BFO_0000054
    ] .

obo:OBI_0000070
    obo:IAO_0000111 "assay"@en ;
    obo:IAO_0000112 "Assay the wavelength of light emitted by excited Neon atoms. Count of geese flying over a house."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies."@en ;
    obo:IAO_0000116 "12/3/12: BP: the reference to the 'physical examination' is included to point out that a prediction is not an assay, as that does not require physical examiniation. " ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000118 "measuring"@en, "scientific observation"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    obo:OBI_0001847 "study assay"^^xsd:string ;
    obo:OBI_9991118 "any method"^^xsd:string ;
    a owl:Class ;
    rdfs:label "assay"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000055 ;
        owl:someValuesFrom obo:OBI_0000067
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000040
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000087 ;
                    owl:someValuesFrom obo:OBI_0000067
                ]
            )
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:IAO_0000027
                [
                    a owl:Restriction ;
                    owl:onProperty obo:IAO_0000136 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:BFO_0000040
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000067
                            ]
                        )
                    ]
                ]
            )
        ]
    ] ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000441
    ] .

obo:OBI_0000079
    obo:IAO_0000111 "culture medium"^^xsd:string ;
    obo:IAO_0000112 "A growth medium or culture medium is a substance in which microorganisms or cells can grow.  Wikipedia, growth medium, Feb 29, 2008"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a processed material that provides the needed nourishment for microorganisms or cells grown in vitro."^^xsd:string ;
    obo:IAO_0000116 """changed from a role to a processed material based on on Aug 22, 2011 dev call. Details see the tracker item: http://sourceforge.net/tracker/?func=detail&aid=3325270&group_id=177891&atid=886178
Modification made by JZ."""^^xsd:string ;
    obo:IAO_0000117 "Person: Jennifer Fostel, Jie Zheng"@en ;
    obo:IAO_0000119 "OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "culture medium"@en ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0000086
    obo:IAO_0000111 "reagent role"^^xsd:string ;
    obo:IAO_0000112 "Buffer, dye, a catalyst, a solvating agent."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer."@en ;
    obo:IAO_0000117 "PERSON:Matthew Brush"@en ;
    obo:IAO_0000118 "reagent"^^xsd:string ;
    obo:IAO_0000119 "PERSON:Matthew Brush"^^xsd:string ;
    obo:IAO_0000232 """Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term.

May 28 2013. Updated definition taken from ReO based on discussions initiated in Philly 2011 workshop.  Former defnition described a narrower view of reagents in chemistry that restricts bearers of the role to be chemical entities (\"a role played by a molecular entity used to produce a chemical reaction to detect, measure, or produce other substances\").  Updated definition allows for broader view of reagents in the domain of biomedical research to include larger materials that have parts that participate chemically in a molecular reaction or interaction.
"""^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment """(copied from ReO)
Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique.  By contrast, instruments do not participate in a chemical reaction/interaction during the technique.

Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not.  It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role.  In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.

In regard to the statement that reagents are 'distinct' from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role.  For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it.  Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).""" ;
    rdfs:label "reagent role"@en ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0000093
    obo:IAO_0000111 "patient role"^^xsd:string ;
    obo:IAO_0000112 "a hospitalized person; a person with controlled diabetes; the patient's role http://www.fertilityjourney.com/testingAndDiagnosis/theRightDoctor/thePatientsRole/index.asp?C=55245395146924652778"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a role which inheres in a person and is realized by the process of being under the care of a physician or health care provider"@en ;
    obo:IAO_0000117 "GROUP:Role Branch"@en ;
    obo:IAO_0000118 "patient"^^xsd:string ;
    obo:IAO_0000119 "OBI, CDISC"@en ;
    obo:IAO_0000232 "CDISC definition:  patient. Person under a physician's care for a particular disease or condition. NOTE: A subject in a clinical trial is not necessarily a patient, but a patient in a clinical trial is a subject. See also subject, trial subject, healthy volunteer. Often used interchangeably"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "patient role"@en ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom obo:NCBITaxon_9606
    ] .

obo:OBI_0000094
    obo:IAO_0000111 "material processing"^^xsd:string ;
    obo:IAO_0000112 "A cell lysis, production of a cloning vector, creating a buffer."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A planned process which results in physical changes in a specified input material"@en ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"@en, "PERSON: Frank Gibson"^^xsd:string, "PERSON: Jennifer Fostel"^^xsd:string, "PERSON: Melanie Courtot"^^xsd:string, "PERSON: Philippe Rocca Serra"^^xsd:string ;
    obo:IAO_0000118 "material transformation"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material processing"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0000047
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:BFO_0000040 ;
        owl:onProperty obo:OBI_0000293
    ] ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000456
    ] .

obo:OBI_0000097
    obo:IAO_0000111 "study subject role"@en ;
    obo:IAO_0000112 """Human subjects in a clinical trial, rats in a toxicogenomics study, tissue cutlures subjected to drug tests, fish observed in an ecotoxicology study. 
Parasite example: people are infected with a parasite which is then extracted; the particpant under investigation could be the parasite, the people, or a population of which the people are members, depending on the nature of the study.
Lake example: a lake could realize this role in an investigation that assays pollution levels in samples of water taken from the lake."""^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected."^^xsd:string ;
    obo:IAO_0000116 "A participant can realize both \"specimen role\" and \"participant under investigation role\" at the same time. However \"participant under investigation role\" is distinct from \"specimen role\", since a specimen could somehow be involved in an investigation without being the thing that is under investigation." ;
    obo:IAO_0000117 "GROUP:  Role Branch"@en ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000232 """Following OBI call November 2012,26th:
 
1. it was decided there was no need for moving the children class and making them siblings of study subject role.
2. it also settles the disambiguation about 'study subject'. This is about the individual participating in the investigation/study, Not the 'topic' (as in 'toxicity study') of the investigation/study

This note closes the issue and validates the class definition to be part of the OBI core
editor = PRS
"""@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "participant under investigation role"@en ;
    rdfs:subClassOf obo:BFO_0000023, [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0000471 ;
        owl:onProperty obo:BFO_0000054
    ] .

obo:OBI_0000102
    obo:IAO_0000111 "responsible party role"^^xsd:string ;
    obo:IAO_0000112 "he THERAPIST has the ability to print a separate statement for the patient and each responsible party. http://www.beaverlog.com/therapist/ez_support/billing/responsible_party_statements.htm"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a study personnel role played by a party who is accountable for the execution of a study component and can make decisions about the conduct of the study"@en ;
    obo:IAO_0000117 "Person: Jennifer Fostel"@en ;
    obo:IAO_0000118 "responsible party"^^xsd:string ;
    obo:IAO_0000119 "OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "responsible party role"@en ;
    rdfs:subClassOf obo:OBI_0000202 .

obo:OBI_0000103
    obo:IAO_0000111 "principal investigator role"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "a responsible party role played by a person responsible for the overall conduct of a study"@en ;
    obo:IAO_0000117 "Person: Jennifer Fostel"@en ;
    obo:IAO_0000118 "principal investigator"^^xsd:string ;
    obo:IAO_0000232 "CDISC definition: A person responsible for the conduct of the clinical trial at a trial site. If a trial is conducted by a team of individuals at a trial site, the investigator is the responsible leader of the team and may be called the principal investigator. 2. The individual principal investigator. 2. The individual under whose immediate direction the test article is administered or dispensed to, or used involving, a subject, or, in the event of an investigation conducted by a team of individuals, is See also sponsor-investigator.; Leiter der klinischen Prufung.Under the German Drug Law, the physician who is head of the clinical investigation (CDISC): coordinating investigator (CDISC) (also study coordinator, MUSC); sponsor-investigator. An individual who both initiates and conducts, alone or with others, a clinical trial, and under whose immediate direction the investigational product is administered to, dispensed to, or used by a subject.NOTE: The term does not include any person other than an individual, hence not a corporation, agency (CDISC)"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "principal investigator role"@en ;
    rdfs:subClassOf obo:OBI_0000102 .

obo:OBI_0000107
    obo:IAO_0000111 "provides_service_consumer_with" ;
    obo:IAO_0000112 "The provides_service_consumer_with relation links the service to its primary process it provides for the consumer (as opposed to secondary processual parts of a service process such as payment or documentation).  For example, a 'DNA sequencing service' provides_service_consumer_with 'DNA sequencing' as the essential process performed by the provider for the client." ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A relation between a service and the primary processual part of the service that is performed by the provider for the consumer." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "provides_service_consumer_with" ;
    rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0000112
    obo:IAO_0000111 "specimen role"^^xsd:string ;
    obo:IAO_0000112 "liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation"@en ;
    obo:IAO_0000116 "22Jun09.  The definition includes whole organisms, and can include a human.  The link between specimen role and study subject role has been removed.  A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role."^^xsd:string, "Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation."^^xsd:string, """blood taken from animal: animal continues in study, whereas blood has role specimen.
something taken from study subject, leaves the study and becomes the specimen."""@en, """parasite example
- when parasite in people we study people, people are subjects and parasites are specimen
- when parasite extracted, they become subject in the following study
specimen can later be subject."""@en ;
    obo:IAO_0000117 "GROUP:  Role Branch"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "specimen role"@en ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000040
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000312 ;
                    owl:someValuesFrom obo:OBI_0000659
                ]
            )
        ]
    ] .

obo:OBI_0000116
    obo:IAO_0000111 "worker role"^^xsd:string ;
    obo:IAO_0000112 "Public sector workers in states that run their own OSHA programs are covered by those states.   http://www.osha.gov/as/opa/worker/index.html"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a personnel role played by a party who executes a component of the study plan; this can occur before, during, after or outside the study timeline"@en ;
    obo:IAO_0000116 "\"executes the study plan\" includes the suppliers and manufacturers of reagents and other materials used in the study"^^xsd:string ;
    obo:IAO_0000117 "Person:Jennifer Fostel"@en ;
    obo:IAO_0000118 "worker"^^xsd:string ;
    obo:IAO_0000119 "OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "worker role"@en ;
    rdfs:subClassOf obo:OBI_0000202 .

obo:OBI_0000124
    obo:IAO_0000111 "is_supported_by_data" ;
    obo:IAO_0000112 "The relation between the conclusion \"Gene tpbA is involved in EPS production\" and the data items produced using two sets of organisms, one being a tpbA knockout, the other being tpbA wildtype tested in polysacharide production assays and analyzed using an ANOVA. "^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process"^^xsd:string ;
    obo:IAO_0000117 "OBI" ;
    obo:IAO_0000119 "OBI", "Philly 2011 workshop"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "is_supported_by_data" .

obo:OBI_0000151
    obo:IAO_0000111 "filter paper"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A device manufacture with the intent to provide a porous unsized paper used for filtering."^^xsd:string ;
    obo:IAO_0000117 "Frank Gibson"^^xsd:string ;
    obo:IAO_0000119 "sep:00107"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "filter paper"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000932, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000378
    ] .

obo:OBI_0000181
    obo:IAO_0000111 "population"@en ;
    obo:IAO_0000112 "PMID12564891. Environ Sci Technol. 2003 Jan 15;37(2):223-8. Effects of historic PCB exposures on the reproductive success of the Hudson River striped bass population."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area"@en ;
    obo:IAO_0000116 """1/28/2013, BP, on the call it was raised that we may want to switch to an external ontology for all populatin terms: 
http://code.google.com/p/popcomm-ontology/""" ;
    obo:IAO_0000117 "PERSON: Philippe Rocca-Serra"@en ;
    obo:IAO_0000119 "adapted from Oxford English Dictionnary"@en ;
    obo:IAO_0000232 "rem1: collection somehow always involve a selection process"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "population"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000202
    obo:IAO_0000111 "investigation agent role"^^xsd:string ;
    obo:IAO_0000112 "The person perform microarray experiments and submit microarray results (including raw data, processed data) with experiment description to ArrayExpress."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing."@en ;
    obo:IAO_0000116 "Implementing a study means carrying out or performing the study and providing reagents or other materials used in the study and other tasks without which the study would not happen."^^xsd:string, "Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable representing investigations run by robot scientists such as ADAM (King et al, Science, 2009)" ;
    obo:IAO_0000117 "GROUP:  Role Branch"@en ;
    obo:IAO_0000118 "investigator"^^xsd:string ;
    obo:IAO_0000119 "OBI"@en ;
    obo:IAO_0000232 "Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    obo:OBI_0001847 "study person role"^^xsd:string ;
    a owl:Class ;
    rdfs:comment "Philly2013: Historically, this role would have been borne only by humans or organizations. However, we now also want to enable investigations run by robot scientists such as ADAM (King et al, Science, 2009)" ;
    rdfs:label "investigation agent role"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000023, [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0000066 ;
        owl:onProperty obo:BFO_0000054
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000023
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000052 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000053 ;
                    owl:someValuesFrom [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0000059 ;
                        owl:someValuesFrom [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000833 ;
                            owl:someValuesFrom [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000050 ;
                                owl:someValuesFrom obo:OBI_0000066
                            ]
                        ]
                    ]
                ]
            ]
        )
    ] .

obo:OBI_0000245
    obo:IAO_0000111 "organization"@en ;
    obo:IAO_0000112 "PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ;
    obo:IAO_0000116 """BP: The definition summarizes long email discussions on the OBI developer, roles, biomaterial and denrie branches. It leaves open if an organization is a material entity or a dependent continuant, as no consensus was reached on that.  The current placement as material is therefore temporary, in order to move forward with development. Here is the entire email summary, on which the definition is based:

1) there are organization_member_roles (president, treasurer, branch
editor), with individual persons as bearers

2) there are organization_roles (employer, owner, vendor, patent holder)

3) an organization has a charter / rules / bylaws, which specify what roles
there are, how they should be realized, and how to modify the
charter/rules/bylaws themselves.

It is debatable what the organization itself is (some kind of dependent
continuant or an aggregate of people). This also determines who/what the
bearer of organization_roles' are. My personal favorite is still to define
organization as a kind of 'legal entity', but thinking it through leads to
all kinds of questions that are clearly outside the scope of OBI.

Interestingly enough, it does not seem to matter much where we place
organization itself, as long as we can subclass it (University, Corporation,
Government Agency, Hospital), instantiate it (Affymetrix, NCBI, NIH, ISO,
W3C, University of Oklahoma), and have it play roles.

This leads to my proposal: We define organization through the statements 1 -
3 above, but without an 'is a' statement for now. We can leave it in its
current place in the is_a hierarchy (material entity) or move it up to
'continuant'. We leave further clarifications to BFO, and close this issue
for now."""@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"^^xsd:string, "PERSON: Bjoern Peters"^^xsd:string, "PERSON: Philippe Rocca-Serra"^^xsd:string, "PERSON: Susanna Sansone"^^xsd:string ;
    obo:IAO_0000119 "GROUP: OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "organization"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0000257
    obo:IAO_0000111 "DNA extraction"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A DNA extraction is a nucleic acid extraction where the desired output material is DNA."@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "DNA extraction"@en ;
    rdfs:subClassOf obo:OBI_0666667, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:CHEBI_16991
    ] .

obo:OBI_0000260
    obo:IAO_0000111 "plan"@en ;
    obo:IAO_0000112 "The plan of researcher X to perform an experiment according to a protocol."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a planned process."@en ;
    obo:IAO_0000116 "This class is included to make clear how the plan specification, the plan, and the planned process relate. OBI will however only subclass and work under the 'plan specification', and 'planned process' class, as we want to avoid to get deep into discussions of 'intend' etc."^^xsd:string ;
    obo:IAO_0000117 "AR, BP, JM, MC, PRS"@en ;
    obo:IAO_0000119 "branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "plan"@en ;
    rdfs:subClassOf obo:BFO_0000017 .

obo:OBI_0000272
    obo:IAO_0000111 "protocol"@en ;
    obo:IAO_0000112 "PCR protocol, has objective specification, amplify DNA fragment of interest, and has action specification describes the amounts of experimental reagents used (e..g. buffers, dNTPS, enzyme), and the temperature and cycle time settings for running the PCR."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process."@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000119 "OBI branch derived + wikipedia (http://en.wikipedia.org/wiki/Protocol_%28natural_sciences%29)"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    obo:OBI_0001847 "study protocol"^^xsd:string ;
    a owl:Class ;
    rdfs:label "protocol"@en ;
    rdfs:subClassOf obo:IAO_0000104 .

obo:OBI_0000274
    obo:IAO_0000111 "adding a material entity into a target"^^xsd:string ;
    obo:IAO_0000112 "Injecting a drug into a mouse. Adding IL-2 to a cell culture. Adding NaCl into water."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'."@en ;
    obo:IAO_0000116 "Class was renamed from 'administering substance', as this is commonly used only for additions into organisms."^^xsd:string ;
    obo:IAO_0000117 "BP"^^xsd:string ;
    obo:IAO_0000119 "branch derived"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "adding a material entity into a target"@en ;
    rdfs:subClassOf obo:OBI_0000652, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000055 ;
        owl:someValuesFrom obo:OBI_0000319
    ], [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000055 ;
        owl:someValuesFrom obo:OBI_0000444
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000040
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000087 ;
                    owl:someValuesFrom obo:OBI_0000319
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0001025 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:BFO_0000040
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000444
                            ]
                        )
                    ]
                ]
            )
        ]
    ] ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000434
    ] .

obo:OBI_0000275
    obo:IAO_0000111 "analyte role"^^xsd:string ;
    obo:IAO_0000112 "Glucose in blood (measured in an assay to determine the concentration of glucose)."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A measurand role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role."@en ;
    obo:IAO_0000116 "interestingly, an analyte is still an analyte even if it is not detected.  for this reason it does not bear a specified input role"^^xsd:string, "pH (technically the inverse log of [H+]) may be considered a quality; this remains to be tested."^^xsd:string, "qualities such as weight, color are not assayed but measured, so they do not fall into this category."^^xsd:string ;
    obo:IAO_0000117 "GROUP: Role Branch"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000232 "Feb 10, 2009.  changes after discussion at OBI Consortium Workshop Feb 2-6, 2009.  accepted as core term."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "analyte role"@en ;
    rdfs:subClassOf obo:OBI_0002444, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000081 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:CHEBI_23367
                obo:CHEBI_33250
            )
        ]
    ] .

obo:OBI_0000293
    obo:IAO_0000111 "has_specified_input"^^xsd:string, "has_specified_input"@en ;
    obo:IAO_0000112 "see is_input_of example_of_usage"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
    obo:IAO_0000116 "8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bjoern Peters"^^xsd:string, "PERSON: Larry Hunter"^^xsd:string, "PERSON: Melanie Coutot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has_specified_input"@en ;
    rdfs:subPropertyOf obo:RO_0000057 ;
    owl:equivalentProperty [
        owl:inverseOf obo:OBI_0000295
    ] .

obo:OBI_0000295
    obo:IAO_0000111 "is_specified_input_of"^^xsd:string ;
    obo:IAO_0000112 "some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en, "PERSON:Bjoern Peters"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "is_specified_input_of"@en ;
    rdfs:subPropertyOf obo:RO_0000056 .

obo:OBI_0000299
    obo:IAO_0000111 "has_specified_output"^^xsd:string, "has_specified_output"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bjoern Peters"^^xsd:string, "PERSON: Larry Hunter"^^xsd:string, "PERSON: Melanie Courtot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has_specified_output"@en ;
    rdfs:subPropertyOf obo:RO_0000057 ;
    owl:equivalentProperty [
        owl:inverseOf obo:OBI_0000312
    ] .

obo:OBI_0000312
    obo:IAO_0000111 "is_specified_output_of"^^xsd:string, "is_specified_output_of"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ;
    obo:IAO_0000117 "Alan Ruttenberg"@en, "PERSON:Bjoern Peters"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "is_specified_output_of"@en ;
    rdfs:subPropertyOf obo:RO_0000056 ;
    owl:equivalentProperty [
        owl:inverseOf obo:OBI_0000299
    ] .

obo:OBI_0000319
    obo:IAO_0000111 "material to be added role"^^xsd:string ;
    obo:IAO_0000112 "drug added to a buffer contained in a tube; substance injected into an animal;"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "material to be added role is a protocol participant role realized by a material which is added into a material bearing the target of material addition role in a material addition process"@en ;
    obo:IAO_0000117 "Role Branch"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000232 "9 March 09 from discussion with PA branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material to be added role"@en ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_0000338
    obo:IAO_0000111 "interpreting data"^^xsd:string ;
    obo:IAO_0000112 "Concluding that a gene is upregulated in a tissue sample based on the band intensity in a western blot.  Concluding that a patient has a infection based on measurement of an elevated body temperature and reported headache. Concluding that there were problems in an investigation because data from PCR and microarray are conflicting. Concluding that 'defects in gene XYZ cause cancer due to improper DNA repair' based on data from experiments in that study that gene XYZ is involved in DNA repair, and the conclusion of a previous study that cancer patients have an increased number of mutations in this gene. "^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion"@en ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"^^xsd:string, "PERSON: Jennifer Fostel"^^xsd:string ;
    obo:IAO_0000119 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "drawing a conclusion based on data"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:IAO_0000027
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0001909
    ] .

obo:OBI_0000339
    obo:IAO_0000111 "planning"^^xsd:string ;
    obo:IAO_0000112 "The process of a scientist thinking about and deciding what reagents to use as part of a protocol for an experiment. Note that the scientist could be human or a \"robot scientist\" executing software."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a process of creating or modifying a plan specification"@en ;
    obo:IAO_0000116 "7/18/2011 BP: planning used to itself be a planned process. Barry Smith pointed out that this would lead to an infinite regression, as there would have to be a plan to conduct a planning process, which in itself would be the result of planning etc. Therefore, the restrictions on 'planning' were loosened to allow for informal processes that result in an 'ad hoc plan '. This required changing from 'has_specified_output some plan specifiction' to 'has_participant some plan specification'. "^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "Bjoern Peters"^^xsd:string, "Plans and Planned Processes Branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "planning"@en ;
    rdfs:subClassOf obo:BFO_0000015, [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000015
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000057 ;
                owl:someValuesFrom obo:IAO_0000104
            ]
        )
    ] .

obo:OBI_0000370
    obo:IAO_0000111 "contain function"@en ;
    obo:IAO_0000112 "A syringe, a beaker"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A contain function is a function to constrain a material entities location in space"@en ;
    obo:IAO_0000117 "Bill Bug"^^xsd:string, "Daniel Schober"^^xsd:string, "Frank Gibson"^^xsd:string, "Melanie Courtot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "contain function"@en ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000371
    obo:IAO_0000111 "heat function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A heat function is a function that increases the internal kinetic energy of a material"@en ;
    obo:IAO_0000117 "Bill Bug"^^xsd:string, "Daniel Schober"^^xsd:string, "Frank Gibson"^^xsd:string, "Melanie Courtot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "heat function"@en ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000372
    obo:IAO_0000111 "material separation function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A material separation function is a function that increases the resolution between two or more material entities. The  to distinction between the entities is usually based on some associated physical quality."@en ;
    obo:IAO_0000117 "Bill Bug"^^xsd:string, "Daniel Schober"^^xsd:string, "Frank Gibson"^^xsd:string, "Melanie Courtot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material separation function"@en ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000378
    obo:IAO_0000111 "filter function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through"@en ;
    obo:IAO_0000117 "Frank Gibson"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "filter function"@en ;
    rdfs:subClassOf obo:OBI_0000372 .

obo:OBI_0000379
    obo:IAO_0000111 "mechanical function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A mechanical function is a function that is realised via mechanical work (through an certain amount of energy transferred by some force)."@en ;
    obo:IAO_0000117 "Bill Bug"^^xsd:string, "Daniel Schober"^^xsd:string, "Frank Gibson"^^xsd:string, "Melanie Courtot"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Mechanical_work"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "mechanical function"@en ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000383
    obo:IAO_0000111 "transfer function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A transfer function is a function to displace a material from one location to another."@en ;
    obo:IAO_0000117 "Bill Bug"^^xsd:string, "Daniel Schober"^^xsd:string, "Frank Gibson"^^xsd:string, "Melanie Courtot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "transfer function"@en ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000387
    obo:IAO_0000111 "cool function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A cool function is a function to decrease the internal kinetic energy of a material below the initial kinetic energy of that type of material."@en ;
    obo:IAO_0000117 "Daniel Schober"^^xsd:string, "Frank Gibson"^^xsd:string, "Melanie Courtot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cool function"@en ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000397
    obo:IAO_0000111 "image acquisition function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An image acquisition function is a function to acquire an image of a material"@en ;
    obo:IAO_0000117 "Frank Gibson"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "image acquisition function"@en ;
    rdfs:subClassOf obo:OBI_0000453, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom obo:OBI_0000398
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0001007 ;
        owl:onProperty obo:BFO_0000054
    ] .

obo:OBI_0000398
    obo:IAO_0000111 "image acquisition device"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An image creation device is a device which captures a digitized image of an object"^^xsd:string ;
    obo:IAO_0000117 "Frank Gibson"^^xsd:string ;
    obo:IAO_0000118 "image acquisition device"^^xsd:string ;
    obo:IAO_0000119 "sep:00096"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "image creation device"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000832 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000968
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000085 ;
                owl:someValuesFrom obo:OBI_0000397
            ]
        )
    ] .

obo:OBI_0000399
    obo:IAO_0000111 "solid support function"^^xsd:string ;
    obo:IAO_0000112 "Taped, glued, pinned, dried or molecularly bonded to a solid support"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A solid support function is a function of a device on which an entity is kept in a defined position and prevented in its movement"@en ;
    obo:IAO_0000117 "Daniel Schober"^^xsd:string, "Frank Gibson"^^xsd:string, "Melanie Courtot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "solid support function"@en ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000401
    obo:IAO_0000111 "environment control function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An environmental control function is a function that regulates a contained environment within specified parameter ranges. For example the control of light exposure, humidity and temperature."@en ;
    obo:IAO_0000117 "Bill Bug"^^xsd:string, "Daniel Schober"^^xsd:string, "Frank Gibson"^^xsd:string, "Melanie Courtot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "environment control function"@en ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000417
    obo:IAO_0000111 "achieves_planned_objective"^^xsd:string ;
    obo:IAO_0000112 "A cell sorting process achieves the objective specification 'material separation objective'"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process."^^xsd:string ;
    obo:IAO_0000117 "BP, AR, PPPB branch"^^xsd:string ;
    obo:IAO_0000119 "PPPB branch derived"^^xsd:string ;
    obo:IAO_0000232 "modified according to email thread from 1/23/09 in accordince with DT and PPPB branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "achieves_planned_objective"^^xsd:string .

obo:OBI_0000423
    obo:IAO_0000111 "extract"@en ;
    obo:IAO_0000112 "Up-regulation of inflammatory signalings by areca nut extract and role of cyclooxygenase-2 -1195G>a polymorphism reveal risk of oral cancer. Cancer Res. 2008 Oct 15;68(20):8489-98. PMID: 18922923"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "an extract is a material entity which results from an extraction process"@en ;
    obo:IAO_0000117 "PERSON: Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000118 "extracted material"@en ;
    obo:IAO_0000119 "GROUP: OBI Biomatrial Branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "extract"@en ;
    rdfs:subClassOf obo:OBI_0000047, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0302884
    ] .

obo:OBI_0000425
    obo:IAO_0000111 "averaging objective"@en ;
    obo:IAO_0000112 "A mean calculation which has averaging objective is a descriptive statistics calculation in which the mean is calculated by taking the sum of all of the observations in a data set divided by the total number of observations. It gives a measure of the 'center of gravity' for the data set. It is also known as the first moment."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation."@en ;
    obo:IAO_0000117 "Elisabetta Manduchi"^^xsd:string, "James Malone"@en ;
    obo:IAO_0000119 "PERSON: Elisabetta Manduchi"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "averaging objective"@en ;
    rdfs:subClassOf obo:OBI_0200166 .

obo:OBI_0000434
    obo:IAO_0000111 "adding material objective"^^xsd:string ;
    obo:IAO_0000112 "creating a mouse infected with LCM virus"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity"@en ;
    obo:IAO_0000117 "BP"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "adding material objective"@en ;
    rdfs:subClassOf obo:OBI_0000686 .

obo:OBI_0000436
    obo:IAO_0000111 "needle"^^xsd:string ;
    obo:IAO_0000112 "Ovarian carcinoma presenting with axillary lymph node metastasis: A case diagnosed by fine-needle aspiration and brief review of the literature.  Diagn Cytopathol. 2008 Oct 16. PMID: 18925569"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A needle is a sharp, hollow device used to penetrate tissue or soft material. When attached to a syringe. it allows delivery of a specific volume of liquid or gaseous mixture."^^xsd:string ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "OBI Instrument"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "needle"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000968 .

obo:OBI_0000437
    obo:IAO_0000111 "analyte measurement objective"^^xsd:string ;
    obo:IAO_0000112 "The objective to measure the concentration of glucose in a blood sample"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "an assay objective to determine the presence or concentration of an analyte in the evaluant"@en ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "PPPB branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "analyte measurement objective"@en ;
    rdfs:subClassOf obo:OBI_0000441 .

obo:OBI_0000441
    obo:IAO_0000111 "assay objective"^^xsd:string ;
    obo:IAO_0000112 "the objective to determine the weight of a mouse."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)"@en ;
    obo:IAO_0000117 "PPPB branch"^^xsd:string ;
    obo:IAO_0000119 "PPPB branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "assay objective"@en ;
    rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0000443
    obo:IAO_0000111 "analyte assay" ;
    obo:IAO_0000112 "example of usage: In lab test for blood glucose, the test is the assay, the blood bears evaluant_role and glucose bears the analyte role. The evaluant is considered an input to the assay and the information entity that records the measurement of glucose concentration the output"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant."^^xsd:string ;
    obo:IAO_0000117 "Alan Ruttenberg"^^xsd:string, "Bjoern Peters"^^xsd:string, "Helen Parkinson"^^xsd:string, "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "Alan Ruttenberg"^^xsd:string, "Bjoern Peters"^^xsd:string, "Helen Parkinson"^^xsd:string, "OBI Planned process branch"^^xsd:string, "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "analyte assay" ;
    rdfs:subClassOf obo:OBI_0000070, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:IAO_0000109
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000437
    ] .

obo:OBI_0000444
    obo:IAO_0000111 "target of material addition role"^^xsd:string ;
    obo:IAO_0000112 "peritoneum of an animal receiving an interperitoneal injection; solution in a tube receiving additional material; location of absorbed material following a dermal application."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "target of material addition role is a role realized by an entity into which a material is added in a material addition process"^^xsd:string ;
    obo:IAO_0000116 "From Branch discussion with BP, AR, MC -- there is a need for the recipient to interact with the administered material.  for example, a tooth receiving a filling was not considered to be a target role."^^xsd:string ;
    obo:IAO_0000117 "GROUP:  Role Branch"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "target of material addition role"@en ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0000274 ;
        owl:onProperty obo:BFO_0000054
    ] .

obo:OBI_0000450
    obo:IAO_0000111 "regulatory agency"@en ;
    obo:IAO_0000112 "The US Environmental Protection Agency"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government."@en ;
    obo:IAO_0000117 "GROUP: OBI Biomaterial Branch"^^xsd:string ;
    obo:IAO_0000119 "WEB: en.wikipedia.org/wiki/Regulator"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "regulatory agency"@en ;
    rdfs:subClassOf obo:OBI_0000245 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000245
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000014
            ]
        )
    ] .

obo:OBI_0000453
    obo:IAO_0000111 "measure function"@en ;
    obo:IAO_0000112 "A glucometer measures blood glucose concentration, the glucometer has a measure function."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference."@en ;
    obo:IAO_0000117 "PERSON: Daniel Schober"^^xsd:string, "PERSON: Helen Parkinson"^^xsd:string, "PERSON: Melanie Courtot"^^xsd:string, "PERSON:Frank Gibson"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "measure function"@en ;
    rdfs:subClassOf obo:BFO_0000034, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000079 ;
        owl:someValuesFrom obo:OBI_0000047
    ], [
        a owl:Restriction ;
        owl:allValuesFrom [
            a owl:Restriction ;
            owl:onProperty obo:OBI_0000299 ;
            owl:someValuesFrom obo:IAO_0000109
        ] ;
        owl:onProperty obo:BFO_0000054
    ] .

obo:OBI_0000456
    obo:IAO_0000111 "material transformation objective"^^xsd:string ;
    obo:IAO_0000112 "The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "an objective specifiction that creates an specific output object from input materials."@en ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"^^xsd:string, "PERSON: Frank Gibson"^^xsd:string, "PERSON: Jennifer Fostel"^^xsd:string, "PERSON: Melanie Courtot"^^xsd:string, "PERSON: Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000118 "artifact  creation objective"@en ;
    obo:IAO_0000119 "GROUP: OBI PlanAndPlannedProcess Branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material transformation objective"@en ;
    rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0000457
    obo:IAO_0000111 "manufacturing"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "Manufacturing is a process with the intent to produce a processed material which will have a function for future use. A person or organization (having manufacturer role) is a participant in this process"@en ;
    obo:IAO_0000116 "Manufacturing implies reproducibility and responsibility AR"^^xsd:string, "This includes a single scientist making a processed material for personal use."@en ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"^^xsd:string, "PERSON: Frank Gibson"^^xsd:string, "PERSON: Jennifer Fostel"^^xsd:string, "PERSON: Melanie Courtot"^^xsd:string, "PERSON: Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "GROUP: OBI PlanAndPlannedProcess Branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "manufacturing"@en ;
    rdfs:subClassOf obo:OBI_0000094, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0000047
    ] ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000458
    ] .

obo:OBI_0000458
    obo:IAO_0000111 "manufacturing objective"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "is the objective to manufacture a material of a certain function (device)"@en ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"^^xsd:string, "PERSON: Frank Gibson"^^xsd:string, "PERSON: Jennifer Fostel"^^xsd:string, "PERSON: Melanie Courtot"^^xsd:string, "PERSON: Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "GROUP: OBI PlanAndPlannedProcess Branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "manufacturing objective"@en ;
    rdfs:subClassOf obo:OBI_0000456 .

obo:OBI_0000462
    obo:IAO_0000111 "Affymetrix"^^xsd:string ;
    obo:IAO_0000112 "Affymetrix supplied microarray"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An organization which supplies technology, tools and protocols for use in high throughput applications"^^xsd:string ;
    a obo:OBI_0000835, obo:OBI_0002989, owl:NamedIndividual ;
    rdfs:label "Affymetrix"^^xsd:string .

obo:OBI_0000471
    obo:IAO_0000111 "study design execution"^^xsd:string ;
    obo:IAO_0000112 "injecting a mouse with PBS solution, weighing it, and recording the weight according to a study design."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a planned process that carries out a study design"^^xsd:string ;
    obo:IAO_0000116 "removed axiom has_part some (assay or 'data transformation') per discussion on protocol application mailing list to improve reasoner performance. The axiom is still desired."^^xsd:string ;
    obo:IAO_0000119 "branch derived"^^xsd:string ;
    obo:IAO_0000232 "6/11/9: edited at workshop. Used to be: study design execution is a process with the objective to generate data according to a concretized study design. The execution of a study design is part of an investigation, and minimally consists of an assay or data transformation."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "study design execution"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000011
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000059 ;
                    owl:someValuesFrom obo:OBI_0500000
                ]
            ]
        )
    ] .

obo:OBI_0000571
    obo:IAO_0000111 "manufacturer role"^^xsd:string ;
    obo:IAO_0000112 "With respect to The Accuri C6 Flow Cytometer System, the organization Accuri bears the role manufacturer role.  With respect to a transformed line of tissue culture cells derived by a specific lab, the lab whose personnel isolated the cll line bears the role manufacturer role.  With respect to a specific antibody produced by an individual scientist, the scientist who purifies, characterizes and distributes the anitbody bears the role manufacturer role."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process."^^xsd:string ;
    obo:IAO_0000117 "GROUP:  Role Branch"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "manufacturer role"^^xsd:string ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:NCBITaxon_9606
                obo:OBI_0000245
            )
        ]
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0000457 ;
        owl:onProperty obo:BFO_0000054
    ] .

obo:OBI_0000639
    obo:IAO_0000111 "material separation objective"^^xsd:string ;
    obo:IAO_0000112 "The objective to obtain multiple aliquots of an enzyme preparation. The objective to obtain cells contained in a sample of blood."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "is an objective to transform a material entity into spatially separated components."^^xsd:string ;
    obo:IAO_0000117 "PPPB branch"^^xsd:string ;
    obo:IAO_0000119 "PPPB branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material separation objective"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000456 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:unionOf (obo:OBI_0000678
            obo:OBI_0000681
        )
    ] .

obo:OBI_0000643
    obo:IAO_0000111 "has grain"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car."^^xsd:string ;
    obo:IAO_0000116 "Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form"@en ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en ;
    obo:IAO_0000119 "PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has grain"^^xsd:string ;
    rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0000651
    obo:IAO_0000111 "urine specimen"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a portion of urine collected from an organism"^^xsd:string ;
    obo:IAO_0000116 "4/10/2011BP: It seems to me that the editor notes refer to a previous version, and are no longer relevant. "^^xsd:string, "This could be instead a kind of collection of secreted stuff. Among secreted stuff there is passive, and active. urine is secreted, passiv.  lavage is secreted, active"^^xsd:string, "are we happy calling collection of urine a material separation?"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "urine specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001479, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0600005
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom obo:OBI_0000112
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom obo:UBERON_0001088
    ] .

obo:OBI_0000652
    obo:IAO_0000111 "material combination"^^xsd:string ;
    obo:IAO_0000112 "Mixing two fluids. Adding salt into water. Injecting a mouse with PBS."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "is a material processing with the objective to combine two or more material entities as input into a single material entity as output."^^xsd:string ;
    obo:IAO_0000116 "created at workshop as parent class for 'adding material into target', which is asymmetric, while combination encompasses all addition processes."^^xsd:string ;
    obo:IAO_0000117 "bp"^^xsd:string ;
    obo:IAO_0000119 "bp"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material combination"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000094, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:BFO_0000040
    ] ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000686
    ] .

obo:OBI_0000655
    obo:IAO_0000111 "blood specimen"^^xsd:string ;
    obo:IAO_0000112 "blood drawn from a human for glucose assay"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a material entity derived from a portion of blood collected from an organism"^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "blood specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_2000009, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0600005
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom obo:OBI_0000112
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom obo:UBERON_0000178
    ] .

obo:OBI_0000659
    obo:IAO_0000111 "specimen collection process" ;
    obo:IAO_0000112 "drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A planned process with the objective of collecting a specimen."^^xsd:string ;
    obo:IAO_0000116 "Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation."^^xsd:string, "Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role.", "Philly2013: The specimen_role for the specimen is created during the specimen collection process.", """label  changed to 'specimen collection process' on 10/27/2014, details see tracker:
http://sourceforge.net/p/obi/obi-terms/716/""" ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000118 "specimen collection" ;
    obo:IAO_0000232 "5/31/2012: This process is not necessarily an acquisition, as specimens may be collected from materials already in posession"^^xsd:string, "6/9/09: used at workshop"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "specimen collection process" ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0100051
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000011
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000417 ;
                owl:someValuesFrom obo:OBI_0000684
            ]
        )
    ] .

obo:OBI_0000671
    obo:IAO_0000111 "sample from organism"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000002 ;
    obo:IAO_0000115 "a material obtained from an organism in order to be a representative of the whole"^^xsd:string ;
    obo:IAO_0000116 "5/29: This is a helper class for now"^^xsd:string, "we need to work on this: Is taking a urine sample a material separation process? If not, we will need to specify what 'taking a sample from organism' entails. We can argue that the objective to obtain a urine sample from a patient is enough to call it a material separation process, but it could dilute what material separation was supposed to be about."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "sample from organism"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000747, obo:OBI_0001479, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom obo:UBERON_0000465
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom obo:OBI_0600005
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000740
            ]
        )
    ] .

obo:OBI_0000678
    obo:IAO_0000111 "portioning objective"^^xsd:string ;
    obo:IAO_0000112 "The objective to obtain multiple aliquots of an enzyme preparation."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "portioning objective"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000639 .

obo:OBI_0000679
    obo:IAO_0000111 "average value"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A  data item that is produced as the output of an averaging data transformation and represents the average value of the input data."@en ;
    obo:IAO_0000117 "PERSON: James Malone"^^xsd:string, "PERSON: Monnie McGee"^^xsd:string ;
    obo:IAO_0000118 "arithmetic mean"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "average value"@en ;
    rdfs:subClassOf obo:IAO_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0200170
    ] .

obo:OBI_0000681
    obo:IAO_0000111 "separation into different composition objective"^^xsd:string ;
    obo:IAO_0000112 "The objective to obtain cells contained in a sample of blood."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities)."^^xsd:string ;
    obo:IAO_0000116 "We should be using has the grain relations or concentrations to distinguish the portioning and other sub-objectives"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "separation into different composition objective"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000639 .

obo:OBI_0000684
    obo:IAO_0000111 "specimen collection objective" ;
    obo:IAO_0000112 "The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A objective specification to obtain a material entity for potential use as an input during an investigation."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "specimen collection objective" ;
    rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0000686
    obo:IAO_0000111 "material combination objective"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "is an objective to obtain an output material that contains several input materials."^^xsd:string ;
    obo:IAO_0000117 "PPPB branch"^^xsd:string ;
    obo:IAO_0000119 "bp"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material combination objective"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000456 .

obo:OBI_0000740
    obo:IAO_0000111 "material sample role"^^xsd:string ;
    obo:IAO_0000112 "a role borne by a portion of blood taken to represent all the blood in an organism; the role borne by a population of humans with HIV enrolled in a study taken to represent patients with HIV in general."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A material sample role is a specimen role borne by a material entity that is the output of a material sampling process."^^xsd:string ;
    obo:IAO_0000116 "7/13/09: Note that this is a relational role: between the sample taken and the 'sampled' material of which the sample is thought to be representative off."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material sample role"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000112 .

obo:OBI_0000747
    obo:IAO_0000111 "material sample"^^xsd:string ;
    obo:IAO_0000112 "blood drawn from patient to measure his systemic glucose level. A population of humans with HIV enrolled in a study taken to represent patients with HIV in general."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A material entity that has the material sample role"^^xsd:string ;
    obo:IAO_0000117 "OBI: workshop"^^xsd:string ;
    obo:IAO_0000118 "sample population"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    obo:OBI_0001847 "sample"^^xsd:string ;
    a owl:Class ;
    rdfs:label "material sample"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0100051 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000740
            ]
        )
    ] .

obo:OBI_0000752
    obo:IAO_0000111 "Thermo"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Thermo"^^xsd:string .

obo:OBI_0000753
    obo:IAO_0000111 "Waters"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Waters"^^xsd:string .

obo:OBI_0000754
    obo:IAO_0000111 "BIO-RAD"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "BIO-RAD"^^xsd:string .

obo:OBI_0000756
    obo:IAO_0000111 "Ambion"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Ambion"^^xsd:string .

obo:OBI_0000757
    obo:IAO_0000111 "Helicos"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Helicos"^^xsd:string .

obo:OBI_0000758
    obo:IAO_0000111 "Roche"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Roche"^^xsd:string .

obo:OBI_0000759
    obo:IAO_0000111 "Illumina"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Illumina"^^xsd:string .

obo:OBI_0000765
    obo:IAO_0000111 "Agilent"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Agilent"^^xsd:string .

obo:OBI_0000769
    obo:IAO_0000111 "Li-Cor"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Li-Cor"^^xsd:string .

obo:OBI_0000770
    obo:IAO_0000111 "Bruker Corporation"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Bruker Corporation"^^xsd:string .

obo:OBI_0000776
    obo:IAO_0000111 "Applied Biosystems"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Applied Biosystems"^^xsd:string .

obo:OBI_0000779
    obo:IAO_0000111 "Bruker Daltonics"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Bruker Daltonics"^^xsd:string .

obo:OBI_0000806
    obo:IAO_0000111 "material maintenance objective"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An objective specification maintains some or all of the qualities of a material over time."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "PERSON: Bjoern Peters"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material maintenance objective"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0000810
    obo:IAO_0000111 "informed consent process"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A planned process in which a person or their legal representative is informed about key facts about potential risks and benefits of a process and makes a documented decision as to whether the person in question will participate."^^xsd:string ;
    obo:IAO_0000116 "09/28/2009 Alan Ruttenberg: This is made a subclass of the higher level processual entity in BFO because I don't want to take a stand on whether it is a process aggregate. Analogous to the situation with Material entity."^^xsd:string ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"^^xsd:string ;
    obo:IAO_0000119 "http://clinicaltrials.gov/ct2/info/glossary#informed"^^xsd:string ;
    obo:IAO_0000232 "2009/09/28 Alan Ruttenberg. Fucoidan-use-case"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "informed consent process"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:NCBITaxon_9606
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000057 ;
        owl:someValuesFrom [
            a owl:Restriction ;
            owl:onProperty obo:RO_0000087 ;
            owl:someValuesFrom obo:OBI_0000202
        ]
    ] .

obo:OBI_0000829
    obo:IAO_0000111 "Sysmex Corporation, Kobe, Japan"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000119 "WEB:http://www.sysmex.com/@2009/08/06"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Sysmex Corporation, Kobe, Japan"^^xsd:string .

obo:OBI_0000832
    obo:IAO_0000111 "measurement device"^^xsd:string ;
    obo:IAO_0000112 "A ruler, a microarray scanner, a Geiger counter."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A device in which a measure function inheres."^^xsd:string ;
    obo:IAO_0000117 "GROUP:OBI Philly workshop"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "measurement device"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000968 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000968
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000085 ;
                owl:someValuesFrom obo:OBI_0000453
            ]
        )
    ] .

obo:OBI_0000833
    obo:IAO_0000111 "objective_achieved_by"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process."^^xsd:string ;
    obo:IAO_0000117 "OBI" ;
    obo:IAO_0000119 "OBI" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "objective_achieved_by"^^xsd:string .

obo:OBI_0000835
    obo:IAO_0000111 "manufacturer"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A person or organization that has a manufacturer role"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "manufacturer"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:unionOf (obo:NCBITaxon_9606
                    obo:OBI_0000245
                )
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000571
            ]
        )
    ] .

obo:OBI_0000836
    obo:IAO_0000111 "test tube"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A test tube is a device consisting of a glass or plastic tubing, open at the top, usually with a rounded U-shaped bottom which has the function to contain material"^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000118 "collection tube"^^xsd:string, "sample tube"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Test_tube"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "test tube"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000967, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000370
    ] .

obo:OBI_0000838
    obo:IAO_0000111 "material maintenance"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "a process with that achieves the objective to maintain some or all of the characteristics of an input material over time"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material maintenance"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000806
    ] .

obo:OBI_0000846
    obo:IAO_0000111 "is member of organization"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "Relating a legal person or organization to an organization in the case where the legal person or organization has a role as member of the organization."^^xsd:string ;
    obo:IAO_0000116 "2009/10/01 Alan Ruttenberg. Barry prefers generic is-member-of. Question of what the range should be. For now organization. Is organization a population? Would the same relation be used to record members of a population"^^xsd:string, "JZ: Discussed on May 7, 2012 OBI dev call. Bjoern points out that we need to allow for organizations to be members of organizations. And agreed by the other OBI developers. So, human and organization were specified in 'Domains'. The textual definition was updated based on it."^^xsd:string ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"^^xsd:string, "Person:Helen Parkinson"^^xsd:string ;
    obo:IAO_0000119 "Person:Alan Ruttenberg"^^xsd:string, "Person:Helen Parkinson"^^xsd:string ;
    obo:IAO_0000232 "2009/09/28 Alan Ruttenberg. Fucoidan-use-case"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "is member of organization"^^xsd:string .

obo:OBI_0000852
    obo:IAO_0000111 "record of missing knowledge"^^xsd:string ;
    obo:IAO_0000112 "A statement in a journal article indicating that the age of a patient at the onset of disease is not known. A statement indicating that the weight of a mouse was not measured."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a information content entity created to indicate that information about something is not available to the person recording it."^^xsd:string ;
    obo:IAO_0000116 "This class should probably end up in IAO. It could be further breaken down to indicate different kinds of lack of knowledge, e.g. inability to determine something vs. no attempt made to determine something vs. no informatino available if it was even attempted to determine something. The design pattern should be generalizable. 'unknown sex' is the first example, and needed immediately."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 ""^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "record of missing knowledge"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0000873
    obo:IAO_0000111 "pre-mortem specimen"^^xsd:string ;
    obo:IAO_0000112 "material obtained through a liver biopsy from a human patient"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a specimen that was taken from a live organism"^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "MO_705 premortem"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pre-mortem specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001506 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0000659
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:OBI_0100026
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000086 ;
                                owl:someValuesFrom obo:PATO_0001421
                            ]
                        )
                    ]
                ]
            )
        ]
    ] .

obo:OBI_0000880
    obo:IAO_0000111 "RNA extract"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string, "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "Group: UPenn Group"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "RNA extract"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001010, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0666666
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000643 ;
        owl:someValuesFrom obo:CHEBI_33697
    ] .

obo:OBI_0000901
    obo:IAO_0000111 "U.S. Food and Drug Administration"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000118 "FDA"^^xsd:string ;
    a obo:OBI_0000450, owl:NamedIndividual ;
    rdfs:label "U.S. Food and Drug Administration"^^xsd:string .

obo:OBI_0000915
    obo:IAO_0000111 "freezing storage"^^xsd:string ;
    obo:IAO_0000112 "a fozen pellet used for later assay"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A storage process in temperature that maintenance the frozen status of the stored entities."^^xsd:string ;
    obo:IAO_0000116 """2010/3/3 Alan Ruttenberg: There is a question of whether we should have a separate objective to \"prepare for maintenance\"
2014/2/3 OBI dev call: \"prepare for maintenance\" is a separate process. For example, 'freezing' and 'flash freezing' are defined and can be used to produce frozen material for storage.
Updated both textual and logical definition. Both input and output material of freezing storage have quality frozen."""^^xsd:string ;
    obo:IAO_0000117 "Person: Alan Ruttenberg, Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000119 "MO_481 frozen_storage"@en, "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "freezing storage"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0302893, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000040
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000086 ;
                            owl:someValuesFrom obo:PATO_0001985
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000299 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:BFO_0000040
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000086 ;
                            owl:someValuesFrom obo:PATO_0001985
                        ]
                    )
                ]
            ]
        )
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000806
    ] .

obo:OBI_0000917
    obo:IAO_0000111 "nasal swab specimen"^^xsd:string ;
    obo:IAO_0000112 "type of sample used in the PCIRN influenza network"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 """A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of
exudate and epithelial debris for microbiological or cellular examination."""^^xsd:string ;
    obo:IAO_0000117 "PERSON: Melanie Courtot"^^xsd:string ;
    obo:IAO_0000119 "WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "nasal swab specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002599, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0002600
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom obo:OBI_0000112
    ] .

obo:OBI_0000922
    obo:IAO_0000111 "frozen specimen"^^xsd:string ;
    obo:IAO_0000112 "Frozen blood plasma"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A specimen that has been frozen in order to store it."^^xsd:string ;
    obo:IAO_0000117 "Person:Alan Ruttenberg"^^xsd:string ;
    obo:IAO_0000119 "MO_610 frozen_sample"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "frozen specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001472 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000915
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000293 ;
                            owl:someValuesFrom [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000112
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000112
            ]
        )
    ] .

obo:OBI_0000927
    obo:IAO_0000111 "lyophilization storage"^^xsd:string ;
    obo:IAO_0000112 ""^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "a storage process with input material entity and output freeze dried material for long time storage"^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string, "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 ""^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "can link to freezing-dying equipment, such as freeze-dryer, rotary evaporator, if needed"^^xsd:string ;
    rdfs:label "lyophilization storage"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0302893, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000806
    ] .

obo:OBI_0000932
    obo:IAO_0000111 "material separation device"^^xsd:string ;
    obo:IAO_0000112 "flow cytometer"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A device with a separation function realized in a planed process"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material separation device"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000968 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000968
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000085 ;
                owl:someValuesFrom obo:OBI_0000372
            ]
        )
    ] .

obo:OBI_0000941
    obo:IAO_0000111 "service consumer role"^^xsd:string ;
    obo:IAO_0000112 "A biologist who uses a sequencing services fulfills the role of a service consumer"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a role which inheres in a person who uses a service"^^xsd:string ;
    obo:IAO_0000117 "Person:Helen Parkinson"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "service consumer role"^^xsd:string ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:NCBITaxon_9606
                obo:OBI_0000245
            )
        ]
    ] .

obo:OBI_0000947
    obo:IAO_0000111 "service provider role"^^xsd:string ;
    obo:IAO_0000112 "Jackson Lab provides experimental animals, EBI provides training on databases, a core facility provides access to a DNA sequencer."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person"^^xsd:string ;
    obo:IAO_0000117 "PERSON:Helen Parkinson"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "service provider role"^^xsd:string ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:NCBITaxon_9606
                obo:OBI_0000245
            )
        ]
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0000011 ;
        owl:onProperty obo:BFO_0000054
    ] .

obo:OBI_0000950
    obo:IAO_0000111 "paraffin specimen"^^xsd:string ;
    obo:IAO_0000112 "liver tissue embedded in paraffin"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin"^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string, "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_990 paraffin_sample"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "paraffin specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001472 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000977
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000293 ;
                            owl:someValuesFrom [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000112
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000112
            ]
        )
    ] .

obo:OBI_0000953
    obo:IAO_0000111 "processed specimen"^^xsd:string ;
    obo:IAO_0000112 """A tissue sample that has been sliced and stained for a histology study.
A blood specimen that has been centrifuged to obtain the white blood cells.""" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that has been intentionally physically modified."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "Bjoern Peters"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "A tissue sample that has been sliced and stained for a histology study." ;
    rdfs:label "processed specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047, obo:OBI_0100051 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000047
            obo:OBI_0100051
        )
    ] .

obo:OBI_0000960
    obo:IAO_0000111 "reagent application function"^^xsd:string ;
    obo:IAO_0000112 "An automatic tissue processor automatically applies antibodies and buffers to histological tissue preparations."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A function that is realized when a reagent is automatically added to some research material."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Nicole Vasilevsky, Matthew Brush"^^xsd:string ;
    obo:IAO_0000119 "PERSON: Nicole Vasilevsky, Matthew Brush"^^xsd:string ;
    obo:IAO_0000232 "4/10/2011: It is unclear if we need / want this, or what this is supposed to be for. Lots of the functions we have are reagent specific. Will this only confuse people?"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "reagent application function"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000034 .

obo:OBI_0000965
    obo:IAO_0000111 "lyophilized specimen"^^xsd:string ;
    obo:IAO_0000112 "freezing dried DNA"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string, "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_589 freeze_dried_sample"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "lyophilized specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001472 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000927
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000293 ;
                            owl:someValuesFrom [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000087 ;
                                owl:someValuesFrom obo:OBI_0000112
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000112
            ]
        )
    ] .

obo:OBI_0000967
    obo:IAO_0000111 "container"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A device that can be used to restrict the location of material entities over time"^^xsd:string ;
    obo:IAO_0000116 "03/21/2010: Added to allow classification of children (similar to what we want to do for 'measurement device'. Lookint at what classifies here, we may want to reconsider a contain function assigned to a part of an entity is necessarily also a function of the whole (e.g. is a centrifuge a container because it has test tubes as parts?)"^^xsd:string ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "container"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000968, [
        a owl:Restriction ;
        owl:onProperty obo:OBIB_0000037 ;
        owl:someValuesFrom obo:IAO_0000109
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBIB_0000038 ;
        owl:someValuesFrom obo:IAO_0000109
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000968
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000085 ;
                owl:someValuesFrom obo:OBI_0000370
            ]
        )
    ] .

obo:OBI_0000968
    obo:IAO_0000111 "device"^^xsd:string ;
    obo:IAO_0000112 "A voltmeter is a measurement device which is intended to perform some measure function."^^xsd:string, "An autoclave is a device that sterlizes instruments or contaminated waste by applying high temperature and pressure."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent."^^xsd:string ;
    obo:IAO_0000116 """2012-12-17 JAO: In common lab usage, there is a distinction made between devices and reagents that is difficult to model. Therefore we have chosen to specifically exclude reagents from the definition of \"device\", and are enumerating the types of roles that a reagent can perform.

2013-6-5 MHB: The following clarifications are outcomes of the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions.  Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear.  For example:

(1) An HPLC machine is considered a device, but has a column that holds a stationary phase resin as an operational component.  This resin qualifies as a device if it participates purely in size exclusion, but bears a reagent role that is realized in the running of a column if it interacts electrostatically or chemically with the evaluant. The container the resin is in (“the column”) considered alone is a device. So the entire column as well as the entire HPLC machine are devices that have a reagent as an operating part.

(2) A pH meter is a device, but its electrode component bears a reagent role in virtue of its interacting directly with the evaluant in execution of an assay.

(3) A gel running  box  is a device that has a metallic lead as a component that participates in a chemical reaction with the running buffer when a charge is passed through it.  This metallic lead is considered to have a reagent role as a component of this device realized in the running of a gel.

In the examples above, a reagent is an operational component of a device, but the device itself does not realize a reagent role (as bearing a reagent role is not transitive across the part_of relation).  In this way, the asserted disjointness between a reagent and device holds, as both roles are never realized in the same bearer during execution of an assay.  """^^xsd:string ;
    obo:IAO_0000117 "PERSON: Helen Parkinson"^^xsd:string ;
    obo:IAO_0000118 "instrument"^^xsd:string ;
    obo:IAO_0000119 "OBI development call 2012-12-17."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "device"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0000971
    obo:IAO_0000111 "fresh specimen"^^xsd:string ;
    obo:IAO_0000112 "a liver freshly removed from a rat"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "a specimen that is output of a specimen creation process used for an investigation without storage."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string, "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_730 fresh_sample"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "fresh specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001472 .

obo:OBI_0000977
    obo:IAO_0000111 "paraffin storage"^^xsd:string ;
    obo:IAO_0000112 ""^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a storage process with input organism or anatomical entity and paraffin and output material embedded in paraffin for long term storage"^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string, "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "UPenn Group"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "need to specify paraffin or wax is one of specified input of the process"^^xsd:string ;
    rdfs:label "paraffin storage"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0302893, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:OBI_0100026
                obo:UBERON_0000465
            )
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000806
    ] .

obo:OBI_0000981
    obo:IAO_0000111 "agar stab specimen"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "a specimen that is output of a process that cell culture inoculated into agar for long term storage."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string, "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_971 agar_stab"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "agar stab specimen"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001472 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0001003
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0000087 ;
                        owl:someValuesFrom obo:OBI_0000112
                    ]
                ]
            )
        ]
    ] .

obo:OBI_0000982
    obo:IAO_0000111 "computed tomography scanner"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An image acquisition device that generates a three-dimensional image of the inside of an object from a large series of two-dimensional X-ray images taken around a single axis of rotation."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Bjoern Peters"^^xsd:string ;
    obo:IAO_0000118 "CT scanner"^^xsd:string, "X-ray computed tomography scanner"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/X-ray_computed_tomography"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "computed tomography scanner"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000398, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000397
    ] .

obo:OBI_0001000
    obo:IAO_0000111 "questionnaire"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study."@en ;
    obo:IAO_0000116 """JT: It plays a role in collecting data that could be fleshed out more; but I'm thinking it is, in itself, an edited document. 
JZ: based on textual definition of edited document, it can be defined as N&S. I prefer to leave questionnaire as a document now. We can add more restrictions in the future and use that to determine it is an edited document or not. """@en, "Need to clarify if this is a document or a directive information entity (or what their connection is))"^^xsd:string ;
    obo:IAO_0000117 "PERSON: Jessica Turner"@en ;
    obo:IAO_0000119 "Merriam-Webster"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "questionnaire"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0001003
    obo:IAO_0000111 "agar stab storage"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a storage process with input cell culture and agar and output agar stab for long time storage"^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string, "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "UPenn Group"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "need to specify that agar is one of input for this process"^^xsd:string ;
    rdfs:label "agar stab storage"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0302893, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0100060
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000806
    ] .

obo:OBI_0001004
    obo:IAO_0000111 "Edingburgh handedness inventory"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "The Edinburgh Handedness Inventory is a set of questions used to assess the dominance of a person's right or left hand in everyday activities. "@en ;
    obo:IAO_0000117 "PERSON:Alan Ruttenberg"^^xsd:string, "PERSON:Jessica Turner"^^xsd:string ;
    obo:IAO_0000119 "PMID:5146491#Oldfield, R.C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97-113"^^xsd:string, "WEB:http://www.cse.yorku.ca/course_archive/2006-07/W/4441/EdinburghInventory.html"^^xsd:string ;
    a obo:OBI_0001000, owl:NamedIndividual ;
    rdfs:label "Edingburgh handedness inventory"^^xsd:string .

obo:OBI_0001007
    obo:IAO_0000111 "image acquisition"^^xsd:string ;
    obo:IAO_0000112 "Taking a polaroid picture of a patients skin lesion; Using a digital camera to take a picture of a gel"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A planned process that captures an image of an object."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "image acquisition"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "image creation"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:IAO_0000101
    ] .

obo:OBI_0001010
    obo:IAO_0000111 "nucleic acid extract"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "UPenn Group"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "nucleic acid extract"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000423, obo:OBI_0000953, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom obo:OBI_0666667
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000112
            ]
        )
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000643 ;
        owl:someValuesFrom obo:CHEBI_33696
    ] .

obo:OBI_0001034
    obo:IAO_0000111 "environmental control device"^^xsd:string ;
    obo:IAO_0000112 "A growth chamber is an environmental control device."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An environmental control device is a device which has the function to control some aspect of the environment such as temperature, or humidity."^^xsd:string ;
    obo:IAO_0000117 "Helen Parkinson"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "environmental control device"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000968 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000968
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000085 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:unionOf (obo:OBI_0000371
                        obo:OBI_0000387
                        obo:OBI_0000401
                    )
                ]
            ]
        )
    ] .

obo:OBI_0001051
    obo:IAO_0000111 "DNA extract"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "Group: UPenn group"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "DNA extract"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001010, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0000257
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000643 ;
        owl:someValuesFrom obo:CHEBI_16991
    ] .

obo:OBI_0001064
    obo:IAO_0000111 "automatic tissue processor"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A device for processing histological tissue having a tissue carrier basket suspended from a turntable overlying a plurality of beakers suspended from a carrier plate. The turntable is raised, indexed, and lowered by a suitable driving mechanism to move the tissue basket sequentially through the beakers. Timers can each be programmed to control the movement of the turntable to provide various different cycles for processing the tissue. Some of the beakers are received in individual thermal baths to heat and control the temperature of the substances received in the beakers for treating the tissue."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Erik Segerdell"^^xsd:string ;
    obo:IAO_0000119 "United States Patent 3762362"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "automatic tissue processor"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000968, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000379
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000960
    ] .

obo:OBI_0001156
    obo:IAO_0000111 "age since planting measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since planting, the process of placing a plant in media (e.g. soil) to allow it to grow, which excludes sowing."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_495 planting"^^xsd:string ;
    obo:IAO_0000232 """Discussed by Jie and Chris, proposed to combine with different kinds of processes as initial time point. Proposed 'age measurement assay' is proceeded by some process. The process can be any kind of process defined in OBI. Think it is more flexible. However, it is hard to model  due to lake of temporal predicates on Nov 15, 2010 dev call.
Term proposed by Bjoern on Nov 8, 2010 dev call
Supported by Alan on Nov 15, 2010 dev call"""^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since planting measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001157
    obo:IAO_0000111 "age since hatching measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since hatching, the process of emergence from an egg."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_745 hatching"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since hatching measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001159
    obo:IAO_0000111 "age since egg laying measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since egg laying, the process of the production of egg(s) by an organism."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_767 egg laying"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since egg laying measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001161
    obo:IAO_0000111 "age since germination measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since germination, the process consisting of physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth."^^xsd:string ;
    obo:IAO_0000116 "Definition of germination comes from GO. However, the term is deprecated from GO now because it is a grouping term without biological significance."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_590 germination"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since germination measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001163
    obo:IAO_0000111 "age since eclosion measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since eclosion, the process of emergence of an adult insect from its pupa or cocoon."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_876 eclosion"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since eclosion measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001164
    obo:IAO_0000111 "age since sowing measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since sowing, the process of placing a seed or spore in some media with the intention to invoke germination."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_748 sowing"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since sowing measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001165
    obo:IAO_0000111 "age since coitus measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since coitus, the process of copulation that occurs during the process of sexual reproduction."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_783 coitus"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since coitus measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001167
    obo:IAO_0000111 "age measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A time measurement datum that is the result of measurement of age of an organism"^^xsd:string ;
    obo:IAO_0000116 """note that we are currently defining subtypes of age measurement datum that specify when the age is relative to, e.g. planting, as we don't have adequate temporal predicates yet.
life of bearer doesn't imply organism
this assay measures time not developmental stage. we recognize that development can take different time periods under different conditions such as media / temperature
age as a quality is dubious; we plan to revisit
stages in development are currently handled with controlled vocabulary, such as 2-somite stage """^^xsd:string ;
    obo:IAO_0000117 "PERSON: Alan Ruttenberg, Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_178 Age"^^xsd:string ;
    obo:IAO_0000232 """In MageTab file, we use
initialTimePoint (a process) + age (a number expected) + TimeUnit (definied in UO, such as year, hour, day, etc.)
Now we use the term label indicating the start time point of measuring the age, (number + TimeUnit) are expected instances of the class"""^^xsd:string, """discussed on Nov 15, dev call
All subtype will be defined by textual definition now."""^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age measurement datum"@en ;
    rdfs:subClassOf obo:IAO_0000416, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000221 ;
        owl:someValuesFrom obo:PATO_0000011
    ] .

obo:OBI_0001168
    obo:IAO_0000111 "age since fertilization measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since fertilization, the process of the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote."^^xsd:string ;
    obo:IAO_0000116 "Definition of fertilization comes from GO."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_701 fertilization"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since fertilization measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001169
    obo:IAO_0000111 "age since birth measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of an organism since birth, the process of emergence and separation of offspring from the mother."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_710 birth"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since birth measurement datum"@en ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0001173
    obo:IAO_0000111 "service"^^xsd:string ;
    obo:IAO_0000112 "providing a training course for UCSD employees how to run a DNA sequencer; sequencing a DNA sample provided by a service consumer restricted to non-human samples; giving access to tissue samples in a biobank within OHSU; JAX shipping mice from their colony "^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A planned process in which a service provider performs a task (i.e. a planned process) for a service consumer."^^xsd:string ;
    obo:IAO_0000117 "Carlo; Matt"^^xsd:string ;
    obo:IAO_0000119 "OBI workshop San Diego 2011"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "service"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:OBI_0000011
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000011
            [
                a owl:Class ;
                owl:intersectionOf ([
                        a owl:Restriction ;
                        owl:onProperty obo:BFO_0000055 ;
                        owl:someValuesFrom obo:OBI_0000941
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:BFO_0000055 ;
                        owl:someValuesFrom obo:OBI_0000947
                    ]
                )
            ]
        )
    ] .

obo:OBI_0001213
    obo:IAO_0000111 "eBioscience"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.ebioscience.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "eBioscience"^^xsd:string .

obo:OBI_0001224
    obo:IAO_0000111 "Cytopeia"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.cytopeia.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Cytopeia"^^xsd:string .

obo:OBI_0001287
    obo:IAO_0000111 "Exalpha Biological"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.exalpha.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Exalpha Biological"^^xsd:string .

obo:OBI_0001312
    obo:IAO_0000111 "Apogee Flow Systems"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.apogeeflow.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Apogee Flow Systems"^^xsd:string .

obo:OBI_0001320
    obo:IAO_0000111 "Exbio Antibodies"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.exbio.cz/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Exbio Antibodies"^^xsd:string .

obo:OBI_0001321
    obo:IAO_0000111 "Becton Dickinson (BD Biosciences)"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.bdbiosciences.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Becton Dickinson (BD Biosciences)"^^xsd:string .

obo:OBI_0001338
    obo:IAO_0000111 "Dako Cytomation"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.dakousa.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Dako Cytomation"^^xsd:string .

obo:OBI_0001340
    obo:IAO_0000111 "Millipore"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.guavatechnologies.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Millipore"^^xsd:string .

obo:OBI_0001347
    obo:IAO_0000111 "Antigenix"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.antigenix.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Antigenix"^^xsd:string .

obo:OBI_0001355
    obo:IAO_0000111 "Partec"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.partec.de/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Partec"^^xsd:string .

obo:OBI_0001372
    obo:IAO_0000111 "Beckman Coulter"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.beckmancoulter.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Beckman Coulter"^^xsd:string .

obo:OBI_0001375
    obo:IAO_0000111 "Advanced Instruments Inc. (AI Companies)"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.aicompanies.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Advanced Instruments Inc. (AI Companies)"^^xsd:string .

obo:OBI_0001404
    obo:IAO_0000111 "genetic characteristics information"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes."@en ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Jie Zheng"@en ;
    obo:IAO_0000119 "MO_66 IndividualGeneticCharacteristics"@en ;
    obo:IAO_0000232 """MO definition:
The genotype of the individual organism from which the biomaterial was derived. Individual genetic characteristics include polymorphisms, disease alleles, and haplotypes.

examples in ArrayExpress
wild_type
MutaMouse (CD2F1 mice with lambda-gt10LacZ integration)
AlfpCre; SNF5 flox/knockout
p53 knock out
C57Bl/6 gp130lox/lox MLC2vCRE/+
fer-15; fem-1
df/df
pat1-114/pat1-114 ade6-M210/ade6-M216 h+/h+ (cells are diploid)
"""@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "genetic characteristics information"@en ;
    rdfs:subClassOf obo:IAO_0000027, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:SO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000058 ;
                    owl:someValuesFrom [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0000052 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:CHEBI_33696
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:BFO_0000050 ;
                                    owl:someValuesFrom obo:OBI_0100026
                                ]
                            )
                        ]
                    ]
                ]
            )
        ]
    ] .

obo:OBI_0001424
    obo:IAO_0000111 "Miltenyi Biotec"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.miltenyibiotec.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Miltenyi Biotec"^^xsd:string .

obo:OBI_0001428
    obo:IAO_0000111 "AES Chemunex"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.aeschemunex.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "AES Chemunex"^^xsd:string .

obo:OBI_0001431
    obo:IAO_0000111 "Bentley Instruments"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://bentleyinstruments.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Bentley Instruments"^^xsd:string .

obo:OBI_0001434
    obo:IAO_0000111 "Invitrogen"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.invitrogen.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Invitrogen"^^xsd:string .

obo:OBI_0001443
    obo:IAO_0000111 "Luminex"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.luminexcorp.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Luminex"^^xsd:string .

obo:OBI_0001458
    obo:IAO_0000111 "CytoBuoy"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A supplier of flow cytometry analyzers"^^xsd:string ;
    obo:IAO_0000117 "Karin Breuer"^^xsd:string ;
    obo:IAO_0000119 "WEB:http://www.cytobuoy.com/@2011/04/11"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "CytoBuoy"^^xsd:string .

obo:OBI_0001472
    obo:IAO_0000111 "specimen with known storage state"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A specimen for which it is known whether it has been subjected to storage of a specified type."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_95 BiosourceType"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "specimen with known storage state"@en ;
    rdfs:subClassOf obo:OBI_0100051 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:unionOf (obo:OBI_0000971
            [
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0302893
                    ]
                )
            ]
        )
    ] .

obo:OBI_0001479
    obo:IAO_0000111 "specimen from organism"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm)."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "tissue specimen"@en ;
    obo:IAO_0000119 "MO_954 organism_part"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "specimen from organism"@en ;
    rdfs:subClassOf obo:OBI_0100051 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000112
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0001000 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:unionOf (obo:UBERON_0000465
                        obo:UBERON_0000477
                    )
                ]
            ]
        )
    ] .

obo:OBI_0001506
    obo:IAO_0000111 "specimen with pre- or post-mortem status"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism."^^xsd:string ;
    obo:IAO_0000116 "organizational term, used in description of specimen that is created from known pre- or post-mortem status"^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert, Jie Zheng"^^xsd:string ;
    obo:IAO_0000119 "MO_84 OrganismStatus"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "specimen with pre- or post-mortem status"@en ;
    rdfs:subClassOf obo:OBI_0100051 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0000659
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:OBI_0100026
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0000086 ;
                                owl:someValuesFrom [
                                    a owl:Class ;
                                    owl:unionOf (obo:PATO_0001421
                                        obo:PATO_0001422
                                    )
                                ]
                            ]
                        )
                    ]
                ]
            )
        ]
    ] .

obo:OBI_0001528
    obo:IAO_0000111 "material service"^^xsd:string ;
    obo:IAO_0000112 "A service performing DNA sequencing, a service preforming cell analysis. A service performing cell line immortalization"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A service which has a material entity as specified input and/or specified output."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Carlo Torniai"^^xsd:string, "PERSON: Matthew Brush"^^xsd:string ;
    obo:IAO_0000119 "PERSON: Carlo Torniai"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material service"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001173 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0001173
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000107 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:unionOf ([
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000293 ;
                            owl:someValuesFrom obo:BFO_0000040
                        ]
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000299 ;
                            owl:someValuesFrom obo:BFO_0000040
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0001547
    obo:IAO_0000111 "material analysis service"^^xsd:string ;
    obo:IAO_0000112 "Services performing DNA sequencing or Cell Analysis"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A service in which a service consumer provides some input material and a service provider performs some analysis of this material to generate data that is returned to the service consumer."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Carlo Torniai"^^xsd:string, "PERSON: Matthew Brush"^^xsd:string ;
    obo:IAO_0000119 "PERSON: Matthew Brush"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material analysis service"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001528 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0001528
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000107 ;
                owl:someValuesFrom obo:OBI_0000070
            ]
        )
    ] .

obo:OBI_0001580
    obo:IAO_0000111 "material transport service"^^xsd:string ;
    obo:IAO_0000112 "A service for chemical disposal"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A service in which a service provider facilitates the transport of some material entity to a specified destination for the service consumer."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Carlo Torniai"^^xsd:string, "PERSON: Matthew Brush"^^xsd:string ;
    obo:IAO_0000119 "PERSON: Carlo Torniai"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material transport service"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001528 .

obo:OBI_0001619
    obo:IAO_0000111 "specimen collection time measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A time measurement datum that is the measure of the time when the specimens are collected."@en ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Jie Zheng"@en ;
    obo:IAO_0000118 "collection date"@en ;
    obo:IAO_0000119 "NIAID GSCID-BRC metadata working group"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    obo:OBI_0001886 "Specimen Collection Date" ;
    dc:source "NIAID GSCID-BRC" ;
    a owl:Class ;
    rdfs:label "specimen collection time measurement datum"@en ;
    rdfs:subClassOf obo:IAO_0000416, [
        a owl:Restriction ;
        owl:onProperty obo:IAO_0000136 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:BFO_0000035
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002223 ;
                    owl:someValuesFrom obo:OBI_0000659
                ]
            )
        ]
    ] .

obo:OBI_0001637
    obo:IAO_0000111 "has disposition to bind"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A relationship between two material entitites that each have disposition to form a complex with the other. "^^xsd:string ;
    obo:IAO_0000116 "This is a shortcut relation, and should expand to say that the two material entities have dispositions, point to the process in which they from a complex that realizes those dispositions, and points to the complex in which the two entities are 'bound to' each other"^^xsd:string ;
    obo:IAO_0000119 "IEDB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has disposition to bind"^^xsd:string .

obo:OBI_0001688
    obo:IAO_0000111 "has organization member"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "Relating an organization to a legal person or organization."^^xsd:string ;
    obo:IAO_0000116 """See tracker:
https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_id=177891&atid=886178"""^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has organization member"@en .

obo:OBI_0001755
    obo:IAO_0000111 "selection criterion"@en ;
    obo:IAO_0000112 "rats should be aged between 6 and 8 weeks and weight between 180-250grams"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A directive information entity which defines and states a principle of standard by which selection process may take place."@en ;
    obo:IAO_0000117 "Person: Philippe Rocca-Serra"@en ;
    obo:IAO_0000118 "selection rule"@en ;
    obo:IAO_0000119 "OBI discussion summarized under the following tracker item : http://sourceforge.net/p/obi/obi-terms/678/"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "selection criterion"@en ;
    rdfs:subClassOf obo:IAO_0000033 .

obo:OBI_0001847
    obo:IAO_0000111 "ISA alternative term"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An alternative term used by the ISA tools project (http://isa-tools.org)." ;
    obo:IAO_0000116 """Requested by Alejandra Gonzalez-Beltran
https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891&atid=886178""" ;
    obo:IAO_0000117 "Person: Alejandra Gonzalez-Beltran", "Person: Philippe Rocca-Serra" ;
    obo:IAO_0000119 "ISA tools project (http://isa-tools.org)" ;
    a owl:AnnotationProperty ;
    rdfs:label "ISA alternative term"@en .

obo:OBI_0001855
    obo:IAO_0000111 "Nimblegen"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An organization that focuses on manufacturing target enrichment probe pools for DNA sequencing."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Nimblegen"^^xsd:string .

obo:OBI_0001856
    obo:IAO_0000111 "Pacific Biosciences"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An organization that supplies tools for studying the synthesis and regulation of DNA, RNA and protein. It developed a powerful technology platform called single molecule real-time (SMRT) technology which enables real-time analysis of biomolecules with single molecule resolution."^^xsd:string ;
    obo:IAO_0000117 "Person: Jie Zheng"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Pacific Biosciences"^^xsd:string .

obo:OBI_0001860
    obo:IAO_0000111 "NanoString Technologies"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An organization that supplies life science tools for translational research and molecular diagnostics based on a novel digital molecular barcoding technology. The NanoString platform can provide simple, multiplexed digital profiling of single molecules."^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "NanoString Technologies"^^xsd:string .

obo:OBI_0001866
    obo:IAO_0000111 "secondary cultured cell"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A cultured cell that has been passaged or derives from a cell that has been passaged in culture. "^^xsd:string ;
    obo:IAO_0000116 "The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture following an initial passage.  We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line.  Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture."^^xsd:string ;
    obo:IAO_0000117 "Person: Matthew Brush" ;
    obo:IAO_0000119 "PERSON: Matthew Brush"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "A secondary cultured cell has been passaged in culture or is a descendant of such a cell that is derived through propagation in culture."^^xsd:string ;
    rdfs:label "secondary cultured cell"^^xsd:string ;
    rdfs:subClassOf obo:CL_0000010, [
        a owl:Class ;
        owl:unionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom obo:OBI_0600037
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0001000 ;
                owl:someValuesFrom [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000312 ;
                    owl:someValuesFrom obo:OBI_0600037
                ]
            ]
        )
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom obo:CL_0000001
    ] .

obo:OBI_0001867
    obo:IAO_0000111 "establishing cell line" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics  (e.g. immortalization or some other stable genetic modification, or selection of some defined subset)." ;
    obo:IAO_0000116 "2013-4-20 MHB: For cases of initial establilshment of a line from a primary culture, successive passaging and/or selection processes can confer increasing degrees of genetic stability and compositional homogeneity as compared to the input primary culture. Historically, many texts consider the first passage as the clearest point to define the beginning of a line. However, in practice it is more often that case that more than one passage, and possibly additional selective techniques, may be required before a culture is deemed to have sufficient stability and homogeneity to be considered cell line. This is the view taken in OBI. Regardless, what is important is that some intentional, experimental step has been taken to establish a more homogenous and stable culture that can be characterized and  progatated over time." ;
    obo:IAO_0000117 "Person: Matthew Brush" ;
    obo:IAO_0000119 "PERSON:Matthew Brush" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "establishing cell line" ;
    rdfs:subClassOf obo:OBI_0600036, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:CLO_0000031
    ] .

obo:OBI_0001879
    obo:IAO_0000111 "reagent"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique  to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output." ;
    obo:IAO_0000116 "2013-6-5 MHB: Clarifications regarding the distinction between reagetns and devices were made at the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions.  Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear.  For examples, see editor note on OBI:device." ;
    obo:IAO_0000117 "PERSON:Matthew Brush" ;
    obo:IAO_0000119 "PERSON:Matthew Brush" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment """(copied from ReO)
Reagents are distinguished from devices/instruments that also serve as facilitators in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique.  By contrast, devices do not participate in a chemical reaction/interaction during the technique.

Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not.  It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance can only realize one of these roles in the execution of a given  assay. For example, taq polymerase can bear a reagent role or an evaluant role.  In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated.

In regard to the statement that reagents are 'distinct' from the specified outputs of a technique:  note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role.  For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it.  Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).""" ;
    rdfs:label "reagent"@en ;
    rdfs:subClassOf obo:OBI_0000047, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0000094
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000086
            ]
        )
    ] .

obo:OBI_0001886
    obo:IAO_0000111 "NIAID GSCID-BRC alternative term"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An alternative term used by the National Institute of Allergy and Infectious Diseases (NIAID) Genomic Sequencing Centers for Infectious Diseases (GSCID) and Bioinformatics Resource Centers (BRC)." ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert, Jie Zheng" ;
    obo:IAO_0000119 "NIAID GSCID-BRC metadata working group" ;
    a owl:AnnotationProperty ;
    rdfs:label "NIAID GSCID-BRC alternative term"@en .

obo:OBI_0001905
    obo:IAO_0000111 "secondary cultured cell population" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A cultured cell population that is derived through one or more passages in culture." ;
    obo:IAO_0000116 "The term 'secondary cell culture' is generally used in biological texts/protocols to refer to any culture of cells following an initial passage.  We include it here because there are often a number of passages between a primary culture and the establishment of a stable, homogenous cell line.  Such cultures are considered to be 'secondary cultures' but not 'cell lines' during this intermediate passaging/selection period between their derivation from a 'primary cell culture' and derivation into a 'cell line', which is a more specific type of secondary culture." ;
    obo:IAO_0000117 "PERSON:Matthew Brush" ;
    obo:IAO_0000118 "secondary cell culture sample" ;
    obo:IAO_0000119 "PERSON:Matthew Brush" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "The concept of a 'secondary cultured cell population' covers cell lines as well as cultured cell populations more immediately derived from a primary culture which have yet to achieve adequate genetic stability and compositional homogeneity to be considered a cell line. The extent of the collection of cells in a 'secondary cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture).  Secondary cultured cell populations can be under active culture, stored in a quiescent state for future use, or applied experimentally." ;
    rdfs:label "secondary cultured cell population" ;
    rdfs:subClassOf obo:OBI_0100060, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0600037
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000643 ;
        owl:someValuesFrom obo:OBI_0001866
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0001866 ;
        owl:onProperty obo:OBI_0000643
    ] .

obo:OBI_0001909
    obo:IAO_0000111 "conclusion based on data" ;
    obo:IAO_0000112 """The conclusion that a gene is upregulated in a tissue sample based on the band intensity in a western blot. The conclusion that a patient has a infection based on measurement of an elevated body temperature and reported headache. The conclusion that there were problems in an investigation because data from PCR and microarray are conflicting.
The following are NOT conclusions based on data: data themselves; results from pure mathematics, e.g. \"13 is prime\".""" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An information content entity that is inferred from data." ;
    obo:IAO_0000116 "In the Philly 2013 workshop, we recognized the limitations of \"conclusion textual entity\", and we introduced this as more general. The need for the 'textual entity' term going forward is up for future debate. " ;
    obo:IAO_0000117 "Group:2013 Philly Workshop group" ;
    obo:IAO_0000119 "Group:2013 Philly Workshop group" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "conclusion based on data" ;
    rdfs:subClassOf obo:IAO_0000030, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000124 ;
        owl:someValuesFrom obo:IAO_0000027
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0000338
    ] .

obo:OBI_0001912
    obo:IAO_0000111 "cell freezing medium"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. "^^xsd:string ;
    obo:IAO_0000117 "PERSON: Matthew Brush"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cell freezing medium"@en ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0001927
    obo:IAO_0000111 "specifies value of" ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A relation between a value specification and an entity which the specification is about." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "specifies value of" ;
    rdfs:subPropertyOf obo:IAO_0000136 .

obo:OBI_0001928
    obo:IAO_0000111 "selection"@en ;
    obo:IAO_0000112 "PMID: 24023800.  In this study, a set of eleven genes (VATP16, 60 S, UQCC, SMD3, EF1α, UBQ, SAND, GAPDH, ACT, PsaB, PTB2) was evaluated to identify reference genes during the first hours of interaction (6, 12, 18 and 24 hpi) between two V. vinifera genotypes and P. viticola. Two analyses were used for the selection of reference genes: direct comparison of susceptible, Trincadeira, and resistant, Regent, V. vinifera cultivars at 0 h, 6, 12, 18 and 24 hours post inoculation with P. viticola (genotype effect); and comparison of each genotype with mock inoculated samples during inoculation time-course (biotic stress effect). Three statistical methods were used, GeNorm, NormFinder, and BestKeeper, allowing to identify UBQ, EF1α and GAPDH as the most stable genes for the genotype effect."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A planned process which results in the creation of group of entity from a larger group by the application of predefined criteria."@en ;
    obo:IAO_0000116 "this term refers to  a planned process and therefore is distinct from the notion of 'natural selection', a process covering the operation of natural causes by which those individuals of a species that are best adapted to the environment tend to be preserved and to transmit their characters, while those less adapted die out, so that in the course of generations the degree of adaptation to the environment tends progressively to increase. (as defined by Oxford English Dictionary)"@en ;
    obo:IAO_0000117 "Person: Philippe Rocca-Serra"@en ;
    obo:IAO_0000118 "selection process"@en ;
    obo:IAO_0000119 "OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "selection"@en ;
    rdfs:subClassOf obo:OBI_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000055 ;
        owl:someValuesFrom [
            a owl:Restriction ;
            owl:onProperty obo:RO_0000059 ;
            owl:someValuesFrom obo:OBI_0001755
        ]
    ] .

obo:OBI_0001930
    obo:IAO_0000111 "categorical value specification" ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A value specification that is specifies one category out of a fixed number of nominal categories" ;
    obo:IAO_0000117 "PERSON:Bjoern Peters" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "categorical value specification" ;
    rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0001931
    obo:IAO_0000111 "scalar value specification" ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A value specification that consists of two parts: a numeral and a unit label" ;
    obo:IAO_0000117 "PERSON:Bjoern Peters" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "scalar value specification" ;
    rdfs:subClassOf obo:OBI_0001933, [
        a owl:Restriction ;
        owl:minCardinality "1"^^xsd:nonNegativeInteger ;
        owl:onProperty obo:IAO_0000039
    ], [
        a owl:Restriction ;
        owl:minCardinality "1"^^xsd:nonNegativeInteger ;
        owl:onProperty obo:OBI_0001937
    ] .

obo:OBI_0001933
    obo:IAO_0000111 "value specification" ;
    obo:IAO_0000112 "The value of 'positive' in a classification scheme of \"positive or negative\"; the value of '20g' on the quantitative scale of mass." ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An information content entity that specifies a value within a classification scheme or on a quantitative scale." ;
    obo:IAO_0000116 "This term is currently a descendant of 'information content entity', which requires that it 'is about' something. A value specification of '20g' for a measurement data item of the mass of a particular mouse 'is about' the mass of that mouse. However there are cases where a value specification is not clearly about any particular. In the future we may change 'value specification' to remove the 'is about' requirement." ;
    obo:IAO_0000117 "PERSON:Bjoern Peters" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "value specification" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0001936
    obo:IAO_0000111 "molecular-labeled material"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay" ;
    obo:IAO_0000117 "PERSON:Matthew Brush"^^xsd:string ;
    obo:IAO_0000119 "OBI developer call, 3-12-12" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "molecular-labeled material"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom obo:OBI_0002744
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom obo:OBI_0600038
            ]
        )
    ] .

obo:OBI_0001937
    obo:IAO_0000111 "has specified numeric value" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A relation between a value specification and a number that quantifies it." ;
    obo:IAO_0000116 "A range of 'real' might be better than 'float'. For now we follow 'has measurement value' until we can consider technical issues with SPARQL queries and reasoning." ;
    obo:IAO_0000117 "PERSON: James A. Overton" ;
    obo:IAO_0000119 "OBI" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:DatatypeProperty ;
    rdfs:label "has specified numeric value" ;
    rdfs:subPropertyOf obo:OBI_0002135 .

obo:OBI_0001938
    obo:IAO_0000111 "has value specification" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A relation between an information content entity and a value specification that specifies its value." ;
    obo:IAO_0000117 "PERSON: James A. Overton" ;
    obo:IAO_0000119 "OBI" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has value specification" ;
    rdfs:subPropertyOf obo:BFO_0000051 .

obo:OBI_0002009
    obo:IAO_0000115 "An autolysis value specification that indicates no apparent autolytic destruction of an organism cells or tissues." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a obo:OBIB_0000087, owl:NamedIndividual ;
    rdfs:label "0-non autolyis"@en .

obo:OBI_0002010
    obo:IAO_0000115 "An autolysis value specification that indicates slight autolytic destruction of an organism cells or tissues." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a obo:OBIB_0000087, owl:NamedIndividual ;
    rdfs:label "1-slight autolysis"@en .

obo:OBI_0002011
    obo:IAO_0000115 "An autolysis value specification that indicates moderate autolytic destruction of an organism cells or tissues." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a obo:OBIB_0000087, owl:NamedIndividual ;
    rdfs:label "2-moderate autolysis"@en .

obo:OBI_0002012
    obo:IAO_0000115 "An autolysis value specification that indicates severe autolytic destruction of an organism cells or tissues." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    a obo:OBIB_0000087, owl:NamedIndividual ;
    rdfs:label "3-severe autolysis"@en .

obo:OBI_0002076
    obo:IAO_0000111 "collection of specimens"@en ;
    obo:IAO_0000112 "Blood cells collected from multiple donors over the course of a study."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A material entity that has two or more specimens as its parts."@en ;
    obo:IAO_0000116 "Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/" ;
    obo:IAO_0000117 "Person: Chris Stoeckert, Jie Zheng"@en ;
    obo:IAO_0000119 "OBIB, OBI" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    dc:source "Biobank" ;
    a owl:Class ;
    rdfs:label "collection of specimens"@en ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:OBI_0100051 ;
                owl:onProperty obo:RO_0002351
            ]
        )
    ] .

obo:OBI_0002077
    obo:IAO_0000111 "specimens derived from shared ancestor"@en ;
    obo:IAO_0000112 "Aliquoting one specimen to multiple tubes and the collection of the aliquoted specimens are a specimen family. Slicing a tissue specimen into multiple sections for microscopy."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A collection of specimens derived from one common specimen via one or more material processing process(es)."@en ;
    obo:IAO_0000116 "Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/" ;
    obo:IAO_0000117 "Chris Stoeckert, Jie Zheng"@en ;
    obo:IAO_0000118 "specimen family"@en ;
    obo:IAO_0000119 "Duke Biobank, OBIB, OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    dc:source "Biobank" ;
    a owl:Class ;
    rdfs:label "specimens derived from shared ancestor"@en ;
    rdfs:subClassOf obo:OBI_0002076 .

obo:OBI_0002087
    obo:IAO_0000111 "containing a specimen function"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A contain function that involves physical contact with a specimen. This function is typically performed in such a way that the specimen is usable for an investigation or assay."@en ;
    obo:IAO_0000116 "For details see tracker item: http://sourceforge.net/p/obi/obi-terms/792/"@en ;
    obo:IAO_0000117 "Chris Stoeckert"@en ;
    obo:IAO_0000119 "Duke Biobank, OBIB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    dc:source "Biobank"@en ;
    a owl:Class ;
    rdfs:label "containing a specimen function"@en ;
    rdfs:subClassOf obo:OBI_0000370 .

obo:OBI_0002088
    obo:IAO_0000111 "specimen container"^^xsd:string ;
    obo:IAO_0000112 "COPAN eSwab, CPT vacutainer, PAXgene Blood DNA tube"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A container with the function of containing a specimen."^^xsd:string ;
    obo:IAO_0000116 "For details see tracker item: http://sourceforge.net/p/obi/obi-terms/792/"^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Duke Biobank, OBIB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "specimen container"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000967 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000967
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000085 ;
                owl:someValuesFrom obo:OBI_0002087
            ]
        )
    ] .

obo:OBI_0002089
    obo:IAO_0000111 "physical store"^^xsd:string ;
    obo:IAO_0000112 "a freezer. a humidity controlled box."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A container with an environmental control function."^^xsd:string ;
    obo:IAO_0000116 "For details see tracker item: http://sourceforge.net/p/obi/obi-terms/793/"^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Duke Biobank, OBIB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "physical store"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000967, obo:OBI_0001034 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000967
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000085 ;
                owl:someValuesFrom obo:OBI_0000401
            ]
        )
    ] .

obo:OBI_0002095
    obo:IAO_0000111 "specimen family creation"@en ;
    obo:IAO_0000112 "Aliquoting one specimen to multiple tubes, slicing a tissue specimen into multiple sections, processing blood into buffy coat, red cells, and serum."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A material processing that has as its input a specimen and as its output a collection of specimens."@en ;
    obo:IAO_0000116 "For details see tracker: https://sourceforge.net/p/obi/obi-terms/778/"@en ;
    obo:IAO_0000117 "Mathias Brochhausen, Chris Stoeckert, Jie Zheng"@en ;
    obo:IAO_0000119 "OBI, OBIB"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    dc:source "Biobank"@en ;
    a owl:Class ;
    rdfs:label "specimen family creation"@en ;
    rdfs:subClassOf obo:OBI_0000094, [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000094
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom obo:OBI_0100051
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000299 ;
                owl:someValuesFrom obo:OBI_0002077
            ]
        )
    ] .

obo:OBI_0002123
    obo:IAO_0000111 "IHC slide staining"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A staining using labeled antibodies, i.e. the analytical part of immunohistochemistry. The staining is applied to fixed specimens on slides to identify biomarkers in tissues."@en ;
    obo:IAO_0000117 "Chris Stoeckert, Ned Haubein"@en ;
    obo:IAO_0000119 "http://www.agilent.com/cs/library/technicaloverviews/public/08002_ihc_staining_methods.pdf"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "IHC slide staining"@en ;
    rdfs:subClassOf obo:OBI_0302887, [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0302887
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom obo:OBIB_0000661
            ]
        )
    ] .

obo:OBI_0002124
    obo:IAO_0000111 "H&E slide staining"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A staining using hematoxylin and eosin. The staining is applied to fixed specimens on slides to observe the whole structure and morphology of cells in a tissue; nuclei are stained dark blue/purple while cytoplasm is stained pink."@en ;
    obo:IAO_0000117 "Chris Stoeckert, Ned Haubein"@en ;
    obo:IAO_0000119 "http://www.histalim.com/accueil/activities/our-services/histology/hematoxylin-eosin-2/"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "H&E slide staining"@en ;
    rdfs:subClassOf obo:OBI_0302887, [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0302887
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom obo:OBIB_0000661
            ]
        )
    ] .

obo:OBI_0002125
    obo:IAO_0000111 "H&E-stained fixed tissue slide specimen"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A fixed tissue slide specimen that is the output of H&E slide staining."@en ;
    obo:IAO_0000117 "Chris Stoeckert, Ned Haubein"@en ;
    obo:IAO_0000119 "OBIB, OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "H&E-stained fixed tissue slide specimen"@en ;
    rdfs:subClassOf obo:OBIB_0000661, [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000661
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom obo:OBI_0002124
            ]
        )
    ] .

obo:OBI_0002126
    obo:IAO_0000111 "IHC-stained fixed tissue slide specimen"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A fixed tissue slide specimen that is the output of immunohistochemistry slide staining."@en ;
    obo:IAO_0000117 "Chris Stoeckert, Ned Haubein"@en ;
    obo:IAO_0000118 "immunohistochemistry slide specimen"@en ;
    obo:IAO_0000119 "OBIB, OBI"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "IHC-stained fixed tissue slide specimen"@en ;
    rdfs:subClassOf obo:OBIB_0000661, [
        a owl:Class ;
        owl:intersectionOf (obo:OBIB_0000661
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom obo:OBI_0002123
            ]
        )
    ] .

obo:OBI_0002135
    obo:IAO_0000111 "has specified value"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A relation between a value specification and a literal." ;
    obo:IAO_0000116 "This is not an RDF/OWL object property. It is intended to link a value found in e.g. a database column of 'M' (the literal) to an instance of a value specification class, which can then be linked to indicate that this is about the biological gender of a human subject." ;
    obo:IAO_0000119 "OBI" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:DatatypeProperty ;
    rdfs:label "has specified value"@en .

obo:OBI_0002136
    obo:IAO_0000111 "RNA Integrity Number calculation" ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A data transformation using the RIN algorithm to generate a quality measure of RNA based on features from an electrophoretic trace." ;
    obo:IAO_0000117 "Chris Stoeckert, Bjoern Peters" ;
    obo:IAO_0000118 "RIN calculation" ;
    obo:IAO_0000119 "https://www.agilent.com/cs/library/applications/5989-1165EN.pdf" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "RNA Integrity Number calculation"@en ;
    rdfs:subClassOf obo:OBI_0200000, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:IAO_0000109
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0001938 ;
                    owl:someValuesFrom obo:OBI_0002137
                ]
            )
        ]
    ] .

obo:OBI_0002137
    obo:IAO_0000111 "RNA Integrity Number value specification" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A value specification that specifies the value of the RNA Integrity Number as a real value between 1 (most degraded) and 10 (most intact)." ;
    obo:IAO_0000117 "Chris Stoeckert, Bjoern Peters" ;
    obo:IAO_0000118 "RIN value specification" ;
    obo:IAO_0000119 "OBI" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "RNA Integrity Number value specification"@en ;
    rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0002138
    obo:IAO_0000111 "temperature value specification" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A value specification that specifies the temperature of some thing." ;
    obo:IAO_0000117 "Chris Stoeckert" ;
    obo:IAO_0000119 "OBI" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "temperature value specification"@en ;
    rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0002139
    obo:IAO_0000111 "volume value specification" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A value specification that specifies the volume of some thing." ;
    obo:IAO_0000117 "Chris Stoeckert" ;
    obo:IAO_0000119 "OBI" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "volume value specification"@en ;
    rdfs:subClassOf obo:OBI_0001933, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0001927 ;
                owl:someValuesFrom obo:PATO_0000918
            ]
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:UO_0000095 ;
                owl:onProperty obo:IAO_0000039
            ]
        )
    ] .

obo:OBI_0002140
    obo:IAO_0000111 "temperature measurement assay" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An assay to determine the temperature of an evaluant."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "temperature measurement assay" ;
    rdfs:subClassOf obo:OBI_0000070, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:IAO_0000109
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0001938 ;
                    owl:someValuesFrom obo:OBI_0002138
                ]
            )
        ]
    ] .

obo:OBI_0002141
    obo:IAO_0000111 "volume measurement assay" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An assay to determine the volume of an evaluant."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "volume measurement assay" ;
    rdfs:subClassOf obo:OBI_0000070, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:IAO_0000109
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0001938 ;
                    owl:someValuesFrom obo:OBI_0002139
                ]
            )
        ]
    ] .

obo:OBI_0002145
    obo:IAO_0000111 "antigen specific antibodies assay" ;
    obo:IAO_0000112 "Test performed using antibodies produced by human B-cells that bind with human immunodeficiency virus (HIV) antigens"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An analyte assay that measures the presence or amount of antibodies to a specified antigen."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "antigen specific antibodies assay" ;
    rdfs:subClassOf obo:OBI_0000443 .

obo:OBI_0002146
    obo:IAO_0000111 "HIV antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detect antibodies that bind to human immunodeficiency virus (HIV) antigens."^^xsd:string ;
    obo:IAO_0000116 "HIV-1 and HIV-2 are two different viruses (http://i-base.info/qa/36)"^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HIV I/II Ab assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "HIV antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145 .

obo:OBI_0002147
    obo:IAO_0000111 "HIV group O antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detect antibodies that bind to human immunodeficiency virus (HIV) group O antigens."^^xsd:string ;
    obo:IAO_0000116 "https://www.cdc.gov/mmwr/preview/mmwrhtml/00042810.htm"^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HIV I/II Plus O assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "HIV group O antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145 .

obo:OBI_0002148
    obo:IAO_0000111 "surface HBV antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detect antibodies that bind to hepatitis B virus (HBV) surface antigens."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HBsAb assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "surface HBV antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:GO_0019814
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0001637 ;
                                        owl:someValuesFrom obo:NCBITaxon_10407
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:GO_0019814
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0001637 ;
                            owl:someValuesFrom obo:NCBITaxon_10407
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002149
    obo:IAO_0000111 "core HBV antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detect antibodies that bind to hepatitis B virus (HBV) core antigens."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HBcAb assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "core HBV antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:GO_0019814
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0001637 ;
                                        owl:someValuesFrom obo:NCBITaxon_10407
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:GO_0019814
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0001637 ;
                            owl:someValuesFrom obo:NCBITaxon_10407
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002150
    obo:IAO_0000111 "core HBV IgM antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detectimmunoglobulin M (IgM) antibodies that bind to hepatitis B virus (HBV) core antigens."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HBcAb-IgM assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "core HBV IgM antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:GO_0019814
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0001637 ;
                                        owl:someValuesFrom obo:NCBITaxon_10407
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:GO_0019814
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0001637 ;
                            owl:someValuesFrom obo:NCBITaxon_10407
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002151
    obo:IAO_0000111 "HCV antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detect antibodies that bind to Hepacivirus C (HCV) antigens."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HCV Ab assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "HCV antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:GO_0019814
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0001637 ;
                                        owl:someValuesFrom obo:NCBITaxon_11103
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:GO_0019814
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0001637 ;
                            owl:someValuesFrom obo:NCBITaxon_11103
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002152
    obo:IAO_0000111 "EBV IgG antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detect immunoglobulin G (IgG) antibodies that bind to Epstein-Barr virus (EBV) antigens."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "EBV IgG Ab assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "EBV IgG antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:GO_0019814
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0001637 ;
                                        owl:someValuesFrom obo:NCBITaxon_10376
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:GO_0019814
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0001637 ;
                            owl:someValuesFrom obo:NCBITaxon_10376
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002153
    obo:IAO_0000111 "EBV IgM antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detect immunoglobulin M (IgM) antibodies that bind to Epstein-Barr virus (EBV) antigens."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "EBV IgM Ab assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "EBV IgM antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:GO_0019814
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0001637 ;
                                        owl:someValuesFrom obo:NCBITaxon_10376
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:GO_0019814
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0001637 ;
                            owl:someValuesFrom obo:NCBITaxon_10376
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002154
    obo:IAO_0000111 "CMV antibody assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An antigen specific antibodies assay that is meant to detect antibodies that bind to cytomegalovirus (CMV) antigens."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "CMV Ab assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "CMV antibody assay" ;
    rdfs:subClassOf obo:OBI_0002145, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:GO_0019814
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:OBI_0001637 ;
                                        owl:someValuesFrom obo:NCBITaxon_10358
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:GO_0019814
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0001637 ;
                            owl:someValuesFrom obo:NCBITaxon_10358
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002155
    obo:IAO_0000111 "venereal disease research laboratory test" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An analyte assay that is meant to detect general antibodies that react with substances that are produced by cellular damage caused by Treponema pallidum indicating a syphilis infection. VDRL tests require a microscope and can be done on cerebrospinal fluid as well as blood."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "VDRL test"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "venereal disease research laboratory test" ;
    rdfs:subClassOf obo:OBI_0000443, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom obo:GO_0019814
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom obo:GO_0019814
            ]
        )
    ] .

obo:OBI_0002156
    obo:IAO_0000111 "rapid plasma reagin test" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An analyte assay that is meant to detect with the aid of carbon or charcoal particles general antibodies that react with substances that are produced by cellular damage caused by Treponema pallidum indicating a syphilis infection. RPR tests can be done without a microscope."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "RPR assay"^^xsd:string ;
    obo:IAO_0000119 "url:http://www.differencebetween.net/science/health/difference-between-vdlr-and-rpr/"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "rapid plasma reagin test" ;
    rdfs:subClassOf obo:OBI_0000443, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom obo:GO_0019814
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom obo:GO_0019814
            ]
        )
    ] .

obo:OBI_0002157
    obo:IAO_0000111 "HBV surface antigen assay" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An analyte assay that is meant to detect hepatitis B virus (HBV) surface antigens."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HBsAg assay"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "HBV surface antigen assay" ;
    rdfs:subClassOf obo:OBI_0000443, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0002444
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom obo:NCBITaxon_10407
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom obo:NCBITaxon_10407
            ]
        )
    ] .

obo:OBI_0002158
    obo:IAO_0000111 "HIV-1 nucleic acid testing" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An analyte assay that is meant to detect human immunodeficiency virus (HIV-1) nucleic acids."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HIV-1 NAT"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "HIV-1 nucleic acid testing" ;
    rdfs:subClassOf obo:OBI_0000443 .

obo:OBI_0002159
    obo:IAO_0000111 "HCV nucleic acid testing" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An analyte assay that is meant to detect hepatitis C virus (HCV) nucleic acids."^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"^^xsd:string, "Chris Stoeckert"^^xsd:string, "James Overton"^^xsd:string, "Randi Vita"^^xsd:string ;
    obo:IAO_0000118 "HCV NAT"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/825"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "HCV nucleic acid testing" ;
    rdfs:subClassOf obo:OBI_0000443, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000055 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000275
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:RO_0000052 ;
                            owl:someValuesFrom [
                                a owl:Class ;
                                owl:intersectionOf (obo:CHEBI_33696
                                    [
                                        a owl:Restriction ;
                                        owl:onProperty obo:BFO_0000050 ;
                                        owl:someValuesFrom obo:NCBITaxon_11103
                                    ]
                                )
                            ]
                        ]
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000293 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:CHEBI_33696
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000050 ;
                            owl:someValuesFrom obo:NCBITaxon_11103
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002190
    obo:IAO_0000111 "courier organization" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An organization that delivers messages, packages, and mail." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000118 "courier" ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Courier" ;
    obo:IAO_0000234 "NCI BBRB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "courier organization"@en ;
    rdfs:subClassOf obo:OBI_0000245, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0000947
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000054 ;
                    owl:someValuesFrom obo:OBI_0001580
                ]
            )
        ]
    ] .

obo:OBI_0002191
    obo:IAO_0000111 "courier tracking number" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A centrally registered identifier symbol assigned by a courier organization in order to track the delivery of an item." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "courier tracking number"@en ;
    rdfs:subClassOf obo:IAO_0000577 .

obo:OBI_0002192
    obo:IAO_0000111 "Leica Peloris rapid tissue processor"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An automatic tissue processor that is a dual retort tissue processor manufactured by the Leica company to provide fast, high quality tissue processing for histology laboratories."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "http://drp8p5tqcb2p5.cloudfront.net/fileadmin/downloads_lbs/Leica%20PELORIS/User%20Manuals/Leica_Peloris_manual_EN.pdf"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "Leica Peloris rapid tissue processor"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0001064 .

obo:OBI_0002193
    obo:IAO_0000111 "Thermo Fisher Scientific"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An organization that is an American multinational, biotechnology product development company, created in 2006 by the merger of Thermo Electron and Fisher Scientific."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Thermo_Fisher_Scientific"^^xsd:string ;
    a obo:OBI_0000245, owl:NamedIndividual ;
    rdfs:label "Thermo Fisher Scientific"^^xsd:string .

obo:OBI_0002194
    obo:IAO_0000111 "Microm Ergostar HM200"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A microtome that is manufactured by Microm and uses a vertical cutting stroke common to all rotary microtomes engaged by a horizontal sliding movement. An operating arm replaces the handwheel and is attached to both sides of the instrument for greater convenience to permit control of sectioning from the left or right."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "http://www.ultra-medical.com/Microm-Ergostar-HM200-Microtome/en"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "Microm Ergostar HM200"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0400168 .

obo:OBI_0002195
    obo:IAO_0000111 "microtome blade"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A device that is the part of a microtome used to slice specimens to a desired thickness."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Microtome"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "microtome blade"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000968 .

obo:OBI_0002196
    obo:IAO_0000111 "Sakura Low profile Accu-Edge microtome blade"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A microtome blade that is manufactured by Feather and is disposable. The ultra-sharp blades section specimens without striations, distortion or chattering."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "http://www.sakura.eu/Our-products/item/8/Microtomy/29/Accu-Edge-Disposable-Microtome-Blades"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "Sakura Low profile Accu-Edge microtome blade"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0002195 .

obo:OBI_0002197
    obo:IAO_0000111 "tissue section thickness" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A length measurement datum that is the result of an assay measuring the thickness of a tissue section." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "tissue section thickness"@en ;
    rdfs:subClassOf obo:IAO_0000408 .

obo:OBI_0002198
    obo:IAO_0000111 "molecular analysis facility organization" ;
    obo:IAO_0000112 "An analysis facility that includes analysis of molecular metabolites, as well as the various DNAs and RNAs." ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An organization that provides molecular analysis service." ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis" ;
    obo:IAO_0000118 "MAF" ;
    obo:IAO_0000119 "NCI BBRB, OBIB" ;
    obo:IAO_0000234 "NCI BBRB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "molecular analysis facility organization"@en ;
    rdfs:subClassOf obo:OBI_0000245 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0000245
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000947
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000054 ;
                            owl:someValuesFrom obo:OBI_0001547
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0002199
    obo:IAO_0000111 "reason for lack of data item" ;
    obo:IAO_0000112 "cannot be assessed, not applicable, unknown"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An information content entity that provides an explanation why a data item is not provided."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "reason for lack of data item" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002200
    obo:IAO_0000111 "cannot be assessed determination" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A reason for lack of data item that is the negative output of a determination if assay will provide reliable results."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "cannot be assessed"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cannot be assessed determination" ;
    rdfs:subClassOf obo:OBI_0002199 .

obo:OBI_0002201
    obo:IAO_0000111 "determination if assay will provide reliable results" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A planned process that is used to assess whether an assay will provide reliable results based on the conditions or qualities of the inputs, devices, and other participants of the assay."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "determination if assay will provide reliable results" ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OBI_0002202
    obo:IAO_0000111 "GX" ;
    obo:IAO_0000112 "AJCC 7th edition GX: cannot be assessed."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A cannot be assessed determination for histologic tumor grade."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "GX" ;
    rdfs:subClassOf obo:OBI_0002200 .

obo:OBI_0002203
    obo:IAO_0000111 "pTX" ;
    obo:IAO_0000112 "AJCC 7th edition pTX: cannot be assessed."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A cannot be assessed determination for pathologic primary tumor staging."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pTX" ;
    rdfs:subClassOf obo:OBI_0002200 .

obo:OBI_0002204
    obo:IAO_0000111 "pNX" ;
    obo:IAO_0000112 "AJCC 7th edition pNX: cannot be assessed."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A cannot be assessed determination of pathologic staging of lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pNX" ;
    rdfs:subClassOf obo:OBI_0002200 .

obo:OBI_0002205
    obo:IAO_0000111 "histologic grade according to AJCC 7th edition" ;
    obo:IAO_0000112 " G4: Undifferentiated"^^xsd:string, "G1:Well differentiated "^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the American Joint Committee on Cancer (AJCC) 7th Edition grading system."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "histologic grade according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002206
    obo:IAO_0000111 "G1: Well differentiated" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade according to AJCC 7th edition indicating that the tumor cells and the organization of the tumor tissue appear close to normal."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "G1"^^xsd:string ;
    obo:IAO_0000119 "https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002205, owl:NamedIndividual ;
    rdfs:label "G1: Well differentiated" .

obo:OBI_0002207
    obo:IAO_0000111 "G2: Moderately differentiated" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade according to AJCC 7th edition indicating that the tumor cells are moderately differentiated and reflect an intermediate grade."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "G2"^^xsd:string ;
    obo:IAO_0000119 "https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002205, owl:NamedIndividual ;
    rdfs:label "G2: Moderately differentiated" .

obo:OBI_0002208
    obo:IAO_0000111 "G3: Poorly differentiated" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade according to AJCC 7th edition indicating that the tumor cells are poorly differentiated and do not look like normal cells and tissue."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "G3"^^xsd:string ;
    obo:IAO_0000119 "https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002205, owl:NamedIndividual ;
    rdfs:label "G3: Poorly differentiated" .

obo:OBI_0002209
    obo:IAO_0000111 "G4: Undifferentiated" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade according to AJCC 7th edition indicating that the tumor cells are undifferentiated and do not look like normal cells and tissue."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "G4"^^xsd:string ;
    obo:IAO_0000119 "https://www.cancer.gov/about-cancer/diagnosis-staging/prognosis/tumor-grade-fact-sheet"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002205, owl:NamedIndividual ;
    rdfs:label "G4: Undifferentiated" .

obo:OBI_0002210
    obo:IAO_0000111 "histologic grade according to the Fuhrman Nuclear Grading System" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the Fuhrman Nuclear Grading System."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Histologic Grade (Fuhrman Nuclear Grading System)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "histologic grade according to the Fuhrman Nuclear Grading System" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002211
    obo:IAO_0000111 "G1 (Fuhrman)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are round, uniform, approximately 10um and that nucleoli are inconspicuous or absent."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Grade 1"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002210, owl:NamedIndividual ;
    rdfs:label "G1 (Fuhrman)" .

obo:OBI_0002212
    obo:IAO_0000111 "G2 (Fuhrman)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are slightly irregular, approximately 15um and nucleoli are evident."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Grade 2"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002210, owl:NamedIndividual ;
    rdfs:label "G2 (Fuhrman)" .

obo:OBI_0002213
    obo:IAO_0000111 "G3 (Fuhrman)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei are very irregular, approximately 20um and nucleoli large and prominent."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Grade 3"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002210, owl:NamedIndividual ;
    rdfs:label "G3 (Fuhrman)" .

obo:OBI_0002214
    obo:IAO_0000111 "G4 (Fuhrman)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade according to the Fuhrman Nuclear Grading System indicating that nuclei arei bizarre and multilobulated, 20um or greater and nucleoli are prominent and chromatin clumped."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Grade 4"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002210, owl:NamedIndividual ;
    rdfs:label "G4 (Fuhrman)" .

obo:OBI_0002215
    obo:IAO_0000111 "histologic grade for ovarian tumor" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a histologic grade assigned to a ovarian tumor."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "histologic grade for ovarian tumor" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002216
    obo:IAO_0000111 "histologic grade for ovarian tumor according to a two-tier grading system" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade for ovarian tumor that is from a two-tier histological classification of tumors. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "histologic grade for ovarian tumor according to a two-tier grading system" ;
    rdfs:subClassOf obo:OBI_0002215 .

obo:OBI_0002217
    obo:IAO_0000111 "Low grade ovarian tumor" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is low grade."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Low grade"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002216, owl:NamedIndividual ;
    rdfs:label "Low grade ovarian tumor" .

obo:OBI_0002218
    obo:IAO_0000111 "High grade ovarian tumor" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade for ovarian tumor according to a two-tier grading system indicating that the tumor is high grade."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "High grade"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002216, owl:NamedIndividual ;
    rdfs:label "High grade ovarian tumor" .

obo:OBI_0002219
    obo:IAO_0000111 "histologic grade for ovarian tumor according to the World Health Organization" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade for ovarian tumor that is from a histological classification by the World Health Organization (WHO)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "histologic grade for ovarian tumor according to the World Health Organization" ;
    rdfs:subClassOf obo:OBI_0002215 .

obo:OBI_0002220
    obo:IAO_0000111 "G1 (WHO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is well differentiated."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "G1"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002219, owl:NamedIndividual ;
    rdfs:label "G1 (WHO)" .

obo:OBI_0002221
    obo:IAO_0000111 "G2 (WHO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is moderately differentiated."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "G2"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002219, owl:NamedIndividual ;
    rdfs:label "G2 (WHO)" .

obo:OBI_0002222
    obo:IAO_0000111 "G3 (WHO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is poorly differentiated."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "G3"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002219, owl:NamedIndividual ;
    rdfs:label "G3 (WHO)" .

obo:OBI_0002223
    obo:IAO_0000111 "G4 (WHO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A histologic grade for ovarian tumor according to the World Health Organization indicating that the tumor is undifferentiated."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "G4"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002219, owl:NamedIndividual ;
    rdfs:label "G4 (WHO)" .

obo:OBI_0002224
    obo:IAO_0000111 "pathologic primary tumor stage for colon and rectum according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "pT: Pathologic spread colorectal primary tumor (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic primary tumor stage for colon and rectum according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002225
    obo:IAO_0000111 "pT0 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that there is no evidence of primary tumor."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002224, owl:NamedIndividual ;
    rdfs:label "pT0 (colon)" .

obo:OBI_0002226
    obo:IAO_0000111 "pTis (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating carcinoma in situ (intraepithelial or invasion of lamina propria)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002224, owl:NamedIndividual ;
    rdfs:label "pTis (colon)" .

obo:OBI_0002227
    obo:IAO_0000111 "pT1 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades submucosa."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002224, owl:NamedIndividual ;
    rdfs:label "pT1 (colon)" .

obo:OBI_0002228
    obo:IAO_0000111 "pT2 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades muscularis propria."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002224, owl:NamedIndividual ;
    rdfs:label "pT2 (colon)" .

obo:OBI_0002229
    obo:IAO_0000111 "pT3 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor invades subserosa or into non-peritionealized pericolic or perirectal tissues."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002224, owl:NamedIndividual ;
    rdfs:label "pT3 (colon)" .

obo:OBI_0002230
    obo:IAO_0000111 "pT4a (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor perforates visceral peritoneum."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002224, owl:NamedIndividual ;
    rdfs:label "pT4a (colon)" .

obo:OBI_0002231
    obo:IAO_0000111 "pT4b (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for colon and rectum according to AJCC 7th edition indicating that the tumor directly invades other organs or structures."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002224, owl:NamedIndividual ;
    rdfs:label "pT4b (colon)" .

obo:OBI_0002232
    obo:IAO_0000111 "pathologic primary tumor stage for lung according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "pT: Pathologic spread lung primary tumor (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic primary tumor stage for lung according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002233
    obo:IAO_0000111 "pT0 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that there is no evidence of primary tumor."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT0 (lung)" .

obo:OBI_0002234
    obo:IAO_0000111 "pTis (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating carcinoma in situ."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pTis (lung)" .

obo:OBI_0002235
    obo:IAO_0000111 "pT1 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 3 cm or less in greatest dimension, surrounded by lung or visceral pleura without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT1 (lung)" .

obo:OBI_0002236
    obo:IAO_0000111 "pT1a (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is 2 cm or less in greatest dimension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT1a (lung)" .

obo:OBI_0002237
    obo:IAO_0000111 "pT1b (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 2 cm but not more than 3 cm in greatest dimension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT1b (lung)" .

obo:OBI_0002238
    obo:IAO_0000111 "pT2 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 7 cm or the tumor has any of the following features: involves main bronchus, 2 cm or more distal to the carina, invades visceral pleura, associated with atelectasis or obstructive pneumonitis that extends to the hilar region but does not involve the entire lung."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT2 (lung)" .

obo:OBI_0002239
    obo:IAO_0000111 "pT2a (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 3 cm but not more than 5 cm in greatest dimension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT2a (lung)" .

obo:OBI_0002240
    obo:IAO_0000111 "pT2b (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 5 cm but not more than 7 cm in greatest dimension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT2b (lung)" .

obo:OBI_0002241
    obo:IAO_0000111 "pT3 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor is more than 7 cm or one that directly invades any of: parietal pleura, chest wall (including superior sulcus tumors), diaphragm, phrenic nerve, mediastinal pleura, parietal pericardiu or the tumor is in the main bronchus less than 2 cm distal to the carina but without  involvement of the carina or there is associated atelectasis or obstructive pneumonitis of the entire lung or there is separate tumor nodule(s) in the same lobe as the primary."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT3 (lung)" .

obo:OBI_0002242
    obo:IAO_0000111 "pT4 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for lung according to AJCC 7th edition indicating that the tumor of any size that invades any of the following: mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, carina or there is separate tumor nodule(s) in a different ipsilateral lobe to that of the primary."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002232, owl:NamedIndividual ;
    rdfs:label "pT4 (lung)" .

obo:OBI_0002243
    obo:IAO_0000111 "pathologic primary tumor stage for kidney according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "pT: Pathologic spread kidney primary tumor (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic primary tumor stage for kidney according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002244
    obo:IAO_0000111 "pT0 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that there is no evidence of primary tumor."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT0 (kidney)" .

obo:OBI_0002245
    obo:IAO_0000111 "pT1 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 7 cm or less in greatest dimension and limited to the kidney."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT1 (kidney)" .

obo:OBI_0002246
    obo:IAO_0000111 "pT1a (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is 4 cm or less."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT1a (kidney)" .

obo:OBI_0002247
    obo:IAO_0000111 "pT1b (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 4 cm but not more than 7 cm."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT1b (kidney)" .

obo:OBI_0002248
    obo:IAO_0000111 "pT2 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm in greatest dimension and limited to the kidney."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT2 (kidney)" .

obo:OBI_0002249
    obo:IAO_0000111 "pT2a (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 7 cm but not more than 10 cm."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT2a (kidney)" .

obo:OBI_0002250
    obo:IAO_0000111 "pT2b (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor is more than 10 cm and limited to the kidney."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT2b (kidney)" .

obo:OBI_0002251
    obo:IAO_0000111 "pT3 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor extends into major veins or perinephric tissues but not into the ipsilateral adrenal gland and not beyond the Gerota fascia."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT3 (kidney)" .

obo:OBI_0002252
    obo:IAO_0000111 "pT3a (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into the renal vein or its segmental (muscle containing) branches, or the tumor invades perirenal and/or renal sinus fat (peripelvic) fat but not beyond Gerota fascia."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT3a (kidney)" .

obo:OBI_0002253
    obo:IAO_0000111 "pT3b (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava below diaphragm."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT3b (kidney)" .

obo:OBI_0002254
    obo:IAO_0000111 "pT3c (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor grossly extends into vena cava above the diaphragm or Invades the wall of the vena cava."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT3c (kidney)" .

obo:OBI_0002255
    obo:IAO_0000111 "pT4 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for kidney according to AJCC 7th edition indicating that the tumor invades beyond Gerota fascia (including contiguous extension into the ipsilateral adrenal gland)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002243, owl:NamedIndividual ;
    rdfs:label "pT4 (kidney)" .

obo:OBI_0002256
    obo:IAO_0000111 "pathologic primary tumor stage for ovary according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "pT: Pathologic spread ovarian primary tumor (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic primary tumor stage for ovary according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002257
    obo:IAO_0000111 "pT0 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that there is no evidence of primary tumor."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT0 (ovary)" .

obo:OBI_0002258
    obo:IAO_0000111 "pT1 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to the ovaries (one or both)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT1 (ovary)" .

obo:OBI_0002259
    obo:IAO_0000111 "pT1a (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one ovary; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT1a (ovary)" .

obo:OBI_0002260
    obo:IAO_0000111 "pT1b (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to both ovaries; capsule intact, no tumor on ovarian surface and no malignant cells in ascites or peritoneal washings."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT1b (ovary)" .

obo:OBI_0002261
    obo:IAO_0000111 "pT1c (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor is limited to one or both ovaries with capsule ruptured, tumor on ovarian surface, or malignant cells in ascites or peritoneal washings."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT1c (ovary)" .

obo:OBI_0002262
    obo:IAO_0000111 "pT2 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with pelvic extension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT2 (ovary)" .

obo:OBI_0002263
    obo:IAO_0000111 "pT2a (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension and/or implants on uterus and/or tube(s) and no malignant cells in ascites or peritoneal washings."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT2a (ovary)" .

obo:OBI_0002264
    obo:IAO_0000111 "pT2b (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has extension to other pelvic tissues and no malignant cells in ascites or peritoneal washings."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT2b (ovary)" .

obo:OBI_0002265
    obo:IAO_0000111 "pT2c (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has pelvic extension with malignant cells in ascites or peritoneal washings."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT2c (ovary)" .

obo:OBI_0002266
    obo:IAO_0000111 "pT3 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor involves one or both ovaries with microscopically confirmed peritoneal metastasis outside the pelvis and/or regional lymph node metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT3 (ovary)" .

obo:OBI_0002267
    obo:IAO_0000111 "pT3a (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has microscopic peritoneal metastasis beyond pelvis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT3a (ovary)" .

obo:OBI_0002268
    obo:IAO_0000111 "pT3b (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has macroscopic peritoneal, metastatasis beyond pelvis, 2 cm or less in greatest dimension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT3b (ovary)" .

obo:OBI_0002269
    obo:IAO_0000111 "pT3c (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic primary tumor stage for ovary according to AJCC 7th edition indicating that the tumor has peritoneal metastasis beyond pelvis, more than 2 cm in greatest dimension and/or regional lymph node metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_t/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002256, owl:NamedIndividual ;
    rdfs:label "pT3c (ovary)" .

obo:OBI_0002270
    obo:IAO_0000111 "pathologic lymph node stage for colon and rectum according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic lymph node stage for colon and rectum according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002271
    obo:IAO_0000111 "pN0 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating no regional lymph node metastsis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002270, owl:NamedIndividual ;
    rdfs:label "pN0 (colon)" .

obo:OBI_0002272
    obo:IAO_0000111 "pN1 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1-3 regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002270, owl:NamedIndividual ;
    rdfs:label "pN1 (colon)" .

obo:OBI_0002273
    obo:IAO_0000111 "pN1a (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 1 regional lymph node."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002270, owl:NamedIndividual ;
    rdfs:label "pN1a (colon)" .

obo:OBI_0002274
    obo:IAO_0000111 "pN1b (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 2-3 regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002270, owl:NamedIndividual ;
    rdfs:label "pN1b (colon)" .

obo:OBI_0002275
    obo:IAO_0000111 "pN1c (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating tumor deposit(s), i.e., satellites in the subserosa, or in non-peritonealized pericolic or perirectal soft tissue without regional lymph node metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002270, owl:NamedIndividual ;
    rdfs:label "pN1c (colon)" .

obo:OBI_0002276
    obo:IAO_0000111 "pN2 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 or more regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002270, owl:NamedIndividual ;
    rdfs:label "pN2 (colon)" .

obo:OBI_0002277
    obo:IAO_0000111 "pN2a (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 4 to 6 regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002270, owl:NamedIndividual ;
    rdfs:label "pN2a (colon)" .

obo:OBI_0002278
    obo:IAO_0000111 "pN2b (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for colon and rectum according to AJCC 7th edition indicating metastasis in 7 or more regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002270, owl:NamedIndividual ;
    rdfs:label "pN2b (colon)" .

obo:OBI_0002279
    obo:IAO_0000111 "pathologic lymph node stage for lung according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic lymph node stage for lung according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002280
    obo:IAO_0000111 "pN0 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for lung according to AJCC 7th edition indicating no regional lymph node metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002279, owl:NamedIndividual ;
    rdfs:label "pN0 (lung)" .

obo:OBI_0002281
    obo:IAO_0000111 "pN1 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral peribronchial and/or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002279, owl:NamedIndividual ;
    rdfs:label "pN1 (lung)" .

obo:OBI_0002282
    obo:IAO_0000111 "pN2 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in ipsilateral mediastinal and/or subcarinal lymph node(s)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002279, owl:NamedIndividual ;
    rdfs:label "pN2 (lung)" .

obo:OBI_0002283
    obo:IAO_0000111 "pN3 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for lung according to AJCC 7th edition indicating metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002279, owl:NamedIndividual ;
    rdfs:label "pN3 (lung)" .

obo:OBI_0002284
    obo:IAO_0000111 "pathologic lymph node stage for kidney according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "pN: Pathologic spread kidney lymph nodes (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic lymph node stage for kidney according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002285
    obo:IAO_0000111 "pN0 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is no regional lymph node metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002284, owl:NamedIndividual ;
    rdfs:label "pN0 (kidney)" .

obo:OBI_0002286
    obo:IAO_0000111 "pN1 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for kidney according to AJCC 7th edition indicating that there is regional lymph node metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002284, owl:NamedIndividual ;
    rdfs:label "pN1 (kidney)" .

obo:OBI_0002287
    obo:IAO_0000111 "pathologic lymph node stage for ovary according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "pN: Pathologic spread ovarian lymph nodes (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic lymph node stage for ovary according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002288
    obo:IAO_0000111 "pN0 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is no regional lymph node metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002287, owl:NamedIndividual ;
    rdfs:label "pN0 (ovary)" .

obo:OBI_0002289
    obo:IAO_0000111 "pN1 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic lymph node stage for ovary according to AJCC 7th edition indicating that there is regional lymph node metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_n/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002287, owl:NamedIndividual ;
    rdfs:label "pN1 (ovary)" .

obo:OBI_0002290
    obo:IAO_0000111 "pathologic distant metastases stage for colon according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of colon cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "M: colon distant metastases (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic distant metastases stage for colon according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002291
    obo:IAO_0000111 "cM0 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there are no symptoms or signs of distant metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging#Pathological_M_Categorization_.28cM_and_pM.29"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002290, owl:NamedIndividual ;
    rdfs:label "cM0 (colon)" .

obo:OBI_0002292
    obo:IAO_0000111 "cM1 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is clinical evidence of distant metastases by history, physical examination, imaging studies, or invasive procedures, but without microscopic evidence of the presumed distant metastases."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging#Pathological_M_Categorization_.28cM_and_pM.29"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002290, owl:NamedIndividual ;
    rdfs:label "cM1 (colon)" .

obo:OBI_0002293
    obo:IAO_0000111 "cM1a (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ based on clinical assessment."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002290, owl:NamedIndividual ;
    rdfs:label "cM1a (colon)" .

obo:OBI_0002294
    obo:IAO_0000111 "cM1b (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum based on clinical assessment."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002290, owl:NamedIndividual ;
    rdfs:label "cM1b (colon)" .

obo:OBI_0002295
    obo:IAO_0000111 "pM1 (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that there is microscopic evidence confirming distant metastatic disease."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002290, owl:NamedIndividual ;
    rdfs:label "pM1 (colon)" .

obo:OBI_0002296
    obo:IAO_0000111 "pM1a (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is confined to one organ and histologically confirmed."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002290, owl:NamedIndividual ;
    rdfs:label "pM1a (colon)" .

obo:OBI_0002297
    obo:IAO_0000111 "pM1b (colon)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for colon according to AJCC 7th edition indicating that metastasis is in more than one organ or the peritoneum and histologically confirmed."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/colon/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002290, owl:NamedIndividual ;
    rdfs:label "pM1b (colon)" .

obo:OBI_0002298
    obo:IAO_0000111 "pathologic distant metastases stage for lung according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "M: lung distant metastases (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic distant metastases stage for lung according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002299
    obo:IAO_0000111 "cM0 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is no distant metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002298, owl:NamedIndividual ;
    rdfs:label "cM0 (lung)" .

obo:OBI_0002300
    obo:IAO_0000111 "cM1 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002298, owl:NamedIndividual ;
    rdfs:label "cM1 (lung)" .

obo:OBI_0002301
    obo:IAO_0000111 "cM1a (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is based on clinical assessment and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002298, owl:NamedIndividual ;
    rdfs:label "cM1a (lung)" .

obo:OBI_0002302
    obo:IAO_0000111 "cM1b (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases based on clinical assessment."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002298, owl:NamedIndividual ;
    rdfs:label "cM1b (lung)" .

obo:OBI_0002303
    obo:IAO_0000111 "pM1 (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002298, owl:NamedIndividual ;
    rdfs:label "pM1 (lung)" .

obo:OBI_0002304
    obo:IAO_0000111 "pM1a (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that metastasis is histologically confirmed and a separate tumor nodule(s) in a contralateral lobe; tumor with pleural nodules OR malignant pleural or pericardial effusion."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002298, owl:NamedIndividual ;
    rdfs:label "pM1a (lung)" .

obo:OBI_0002305
    obo:IAO_0000111 "pM1b (lung)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for lung according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed and associated with distant lymph nodes or carcinomatosis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/lung/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002298, owl:NamedIndividual ;
    rdfs:label "pM1b (lung)" .

obo:OBI_0002306
    obo:IAO_0000111 "pathologic distant metastases stage for kidney according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "M: kidney distant Metastases (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic distant metastases stage for kidney according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002307
    obo:IAO_0000111 "cM0 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is no distant metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002306, owl:NamedIndividual ;
    rdfs:label "cM0 (kidney)" .

obo:OBI_0002308
    obo:IAO_0000111 "cM1 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there are distant metastases based on clinical assessment."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002306, owl:NamedIndividual ;
    rdfs:label "cM1 (kidney)" .

obo:OBI_0002309
    obo:IAO_0000111 "pM1 (kidney)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for kidney according to AJCC 7th edition indicating that there is a distant metastases that is histologically confirmed."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/kidney_parenchyma/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002306, owl:NamedIndividual ;
    rdfs:label "pM1 (kidney)" .

obo:OBI_0002310
    obo:IAO_0000111 "pathologic distant metastases stage for ovary according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a  pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "M: ovarian distant metastases (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pathologic distant metastases stage for ovary according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002311
    obo:IAO_0000111 "cM0 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is no distant metastasis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002310, owl:NamedIndividual ;
    rdfs:label "cM0 (ovary)" .

obo:OBI_0002312
    obo:IAO_0000111 "cM1 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis based on clinical assessment."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002310, owl:NamedIndividual ;
    rdfs:label "cM1 (ovary)" .

obo:OBI_0002313
    obo:IAO_0000111 "pM1 (ovary)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pathologic distant metastases stage for ovary according to AJCC 7th edition indicating that there is distant metastasis except peritoneal metastasis that is histologically confirmed."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_m/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002310, owl:NamedIndividual ;
    rdfs:label "pM1 (ovary)" .

obo:OBI_0002314
    obo:IAO_0000111 "clinical tumor stage group according to AJCC 7th edition" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is an assessment of the stage of a cancer according to the American Joint Committee on Cancer (AJCC) v7 staging systems."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Clinical tumor stage group (AJCC 7th Edition)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "clinical tumor stage group according to AJCC 7th edition" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002315
    obo:IAO_0000111 "Occult Carcinoma (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating a small carcinoma, either asymptomatic or giving rise to metastases without symptoms due to the primary carcinoma."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Occult Carcinoma"^^xsd:string ;
    obo:IAO_0000119 "http://www.medilexicon.com/dictionary/14371"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Occult Carcinoma (AJCC 7th)" .

obo:OBI_0002316
    obo:IAO_0000111 "Stage 0 (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating a carcinoma in situ (or melanoma in situ for melanoma of the skin or germ cell neoplasia in situ for testicular germ cell tumors) and generally is considered to have no metastatic potential. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 0"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage 0 (AJCC 7th)" .

obo:OBI_0002317
    obo:IAO_0000111 "Stage I (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers that are smaller or less deeply invasive without regional disease or nodes."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage I"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage I (AJCC 7th)" .

obo:OBI_0002318
    obo:IAO_0000111 "Stage IIA (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIB and IIC."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIA"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage IIA (AJCC 7th)" .

obo:OBI_0002319
    obo:IAO_0000111 "Stage IIB (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIC."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIB"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage IIB (AJCC 7th)" .

obo:OBI_0002320
    obo:IAO_0000111 "Stage IIC (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent but less than in Stage III and with differing characteristics from IIA and IIB."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIC"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage IIC (AJCC 7th)" .

obo:OBI_0002321
    obo:IAO_0000111 "Stage IIIA (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIB and IIIC."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIIA"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage IIIA (AJCC 7th)" .

obo:OBI_0002322
    obo:IAO_0000111 "Stage IIIB (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIC."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIIB"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage IIIB (AJCC 7th)" .

obo:OBI_0002323
    obo:IAO_0000111 "Stage IIIC (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers with increasing tumor or nodal extent greater than in Stage II and with differing characteristics from IIIA and IIIB."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIIC"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage IIIC (AJCC 7th)" .

obo:OBI_0002324
    obo:IAO_0000111 "Stage IVA (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVB."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IVA"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage IVA (AJCC 7th)" .

obo:OBI_0002325
    obo:IAO_0000111 "Stage IVB (AJCC 7th)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical tumor stage group according to AJCC 7th edition indicating cancers in patients who present with distant metastases at diagnosis and with differing characteristics from IVA."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IVB"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002314, owl:NamedIndividual ;
    rdfs:label "Stage IVB (AJCC 7th)" .

obo:OBI_0002326
    obo:IAO_0000111 "International Federation of Gynecology and Obstetrics cervical cancer stage value specification" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is an assessment of the stage of a gynecologic cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging systems."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Clinical FIGO stage"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "International Federation of Gynecology and Obstetrics cervical cancer stage value specification" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002327
    obo:IAO_0000111 "Stage IA (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating invasive carcinoma which can be diagnosed only by microscopy, with deepest invasion <5 mm and the largest extension <7 mm."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IA"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IA (FIGO)" .

obo:OBI_0002328
    obo:IAO_0000111 "Stage IA1 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of <3.0 mm in depth and extension of <7.0 mm."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IA1"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IA1 (FIGO)" .

obo:OBI_0002329
    obo:IAO_0000111 "Stage IA2 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating measured stromal invasion of >3.0 mm and not >5.0 mm with an extension of not >7.0 mm."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IA2"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IA2 (FIGO)" .

obo:OBI_0002330
    obo:IAO_0000111 "Stage IB (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesions limited to the cervix uteri or pre-clinical cancers greater than stage IA"^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IB"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IB (FIGO)" .

obo:OBI_0002331
    obo:IAO_0000111 "Stage IB1 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA <4.0 cm in greatest dimension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IB1"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IB1 (FIGO)" .

obo:OBI_0002332
    obo:IAO_0000111 "Stage IB2 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating clinically visible lesion limited to the cervix uteri or pre-clinical cancers greater than stage IA >4.0 cm in greatest dimension."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IB2"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IB2 (FIGO)" .

obo:OBI_0002333
    obo:IAO_0000111 "Stage IIA (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIA"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IIA (FIGO)" .

obo:OBI_0002334
    obo:IAO_0000111 "Stage IIA1 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion <4.0 cm in greatest dimension. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIA1"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IIA1 (FIGO)" .

obo:OBI_0002335
    obo:IAO_0000111 "Stage IIA2 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina without parametrial invasion and clinically visible lesion >4.0 cm in greatest dimension. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIA2"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IIA2 (FIGO)" .

obo:OBI_0002336
    obo:IAO_0000111 "Stage IIB (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating cervical carcinoma invades beyond the uterus, but not to the pelvic wall or to the lower third of the vagina with obvious parametrial invasion. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIB"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IIB (FIGO)" .

obo:OBI_0002337
    obo:IAO_0000111 "Stage IIIA (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating tumour involves lower third of the vagina, with no extension to the pelvic wall."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIIA"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IIIA (FIGO)" .

obo:OBI_0002338
    obo:IAO_0000111 "Stage IIIB (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating extension to the pelvic wall and/or hydronephrosis or non-functioning kidney."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IIIB"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IIIB (FIGO)" .

obo:OBI_0002339
    obo:IAO_0000111 "Stage IVA (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread of the growth to adjacent organs."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IVA"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IVA (FIGO)" .

obo:OBI_0002340
    obo:IAO_0000111 "Stage IVB (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An International Federation of Gynecology and Obstetrics cervical cancer stage value specification indicating spread to distant organs."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage IVB"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Cervical_cancer_staging"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002326, owl:NamedIndividual ;
    rdfs:label "Stage IVB (FIGO)" .

obo:OBI_0002341
    obo:IAO_0000111 "International Federation of Gynecology and Obstetrics ovarian cancer stage value specification" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the FIGO classification system."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Pathologic Tumor Stage Grouping for ovarian cancer (FIGO)"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "International Federation of Gynecology and Obstetrics ovarian cancer stage value specification" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002342
    obo:IAO_0000111 "Stage 1 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1, N0, and M0."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 1"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 1 (FIGO)" .

obo:OBI_0002343
    obo:IAO_0000111 "Stage 1A (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1a, N0, and M0."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 1A"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 1A (FIGO)" .

obo:OBI_0002344
    obo:IAO_0000111 "Stage 1B (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1b, N0, and M0."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 1B"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 1B (FIGO)" .

obo:OBI_0002345
    obo:IAO_0000111 "Stage 1C (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T1c, N0, and M0."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 1C"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 1C (FIGO)" .

obo:OBI_0002346
    obo:IAO_0000111 "Stage 2 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2, N0, and M0."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 2"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 2 (FIGO)" .

obo:OBI_0002347
    obo:IAO_0000111 "Stage 2A (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2a, N0, and M0."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 2A"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 2A (FIGO)" .

obo:OBI_0002348
    obo:IAO_0000111 "Stage 2B (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2b, N0, and M0."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 2B"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 2B (FIGO)" .

obo:OBI_0002349
    obo:IAO_0000111 "Stage 2C (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T2c, N0, and M0."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 2C"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 2C (FIGO)" .

obo:OBI_0002350
    obo:IAO_0000111 "Stage 3 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3, N0, and M0) or (T3,3a,3b, NX, and M0)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 3"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 3 (FIGO)" .

obo:OBI_0002351
    obo:IAO_0000111 "Stage 3A (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3a, N0, and M0 ."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 3A"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 3A (FIGO)" .

obo:OBI_0002352
    obo:IAO_0000111 "Stage 3B (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of T3b, N0, and M0 ."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 3B"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 3B (FIGO)" .

obo:OBI_0002353
    obo:IAO_0000111 "Stage 3C (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T3c, N0,X and M0) or (any T, N1 and M0)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 3C"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 3C (FIGO)" .

obo:OBI_0002354
    obo:IAO_0000111 "Stage 4 (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of any T, any N, and M1."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage 4"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage 4 (FIGO)" .

obo:OBI_0002355
    obo:IAO_0000111 "Stage Unknown (FIGO)" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A International Federation of Gynecology and Obstetrics ovarian cancer stage value specification associated with TNM stage values of (T0, N0, and M0) or (T1,1a-1c,2,2a-2c, NX, and M0) or (TX, N0,X, M0)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Stage Unknown"^^xsd:string ;
    obo:IAO_0000119 "https://staging.seer.cancer.gov/tnm/input/1.0/ovary/path_stage_group_direct/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002341, owl:NamedIndividual ;
    rdfs:label "Stage Unknown (FIGO)" .

obo:OBI_0002356
    obo:IAO_0000111 "performance status value specification" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A categorical value specification that is an assessment of a participant's performance status (general well-being and activities of daily life)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Performance Status Scale"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Performance_status"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "performance status value specification" ;
    rdfs:subClassOf obo:OBI_0001930 .

obo:OBI_0002357
    obo:IAO_0000111 "Eastern Cooperative Oncology Group score value specification" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A performance status value specification designed by the Eastern Cooperative Oncology Group to assess disease progression and its affect on the daily living abilities of the patient."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "ECOG score"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "Eastern Cooperative Oncology Group score value specification" ;
    rdfs:subClassOf obo:OBI_0002356 .

obo:OBI_0002358
    obo:IAO_0000111 "3: symptomatic in bed more than 50% of the day but not bed ridden" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and in bed for more than 50% of the day but is not bed ridden."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002357, owl:NamedIndividual ;
    rdfs:label "3: symptomatic in bed more than 50% of the day but not bed ridden" .

obo:OBI_0002359
    obo:IAO_0000111 "2: symptomatic but in bed less than 50% of the day" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is in bed for less than 50% of the day."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002357, owl:NamedIndividual ;
    rdfs:label "2: symptomatic but in bed less than 50% of the day" .

obo:OBI_0002360
    obo:IAO_0000111 "4: bed ridden" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic and is bed ridden."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002357, owl:NamedIndividual ;
    rdfs:label "4: bed ridden" .

obo:OBI_0002361
    obo:IAO_0000111 "0: asymptomatic" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An Eastern Cooperative Oncology Group score value specification indicating a patient is asymptomatic."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002357, owl:NamedIndividual ;
    rdfs:label "0: asymptomatic" .

obo:OBI_0002362
    obo:IAO_0000111 "1: symptomatic but fully ambulatory" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An Eastern Cooperative Oncology Group score value specification indicating a patient is symptomatic but is fully ambulatory."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002357, owl:NamedIndividual ;
    rdfs:label "1: symptomatic but fully ambulatory" .

obo:OBI_0002363
    obo:IAO_0000111 "Karnofsky score vaue specification" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A performance status value specification designed for classifying patients 16 years of age or older by their functional impairment."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "Karnofsky Score"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "Karnofsky score vaue specification" ;
    rdfs:subClassOf obo:OBI_0002356 .

obo:OBI_0002364
    obo:IAO_0000111 "100: asymptomatic" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A Karnofsky score vaue specification indicating that a patient is asymptomatic."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002363, owl:NamedIndividual ;
    rdfs:label "100: asymptomatic" .

obo:OBI_0002365
    obo:IAO_0000111 "80-90: symptomatic but fully ambulatory" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A Karnofsky score vaue specification indicating that a patient is symptomatic but fully ambulatory."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002363, owl:NamedIndividual ;
    rdfs:label "80-90: symptomatic but fully ambulatory" .

obo:OBI_0002366
    obo:IAO_0000111 "60-70: symptomatic but in bed less than 50% of the day" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A Karnofsky score vaue specification indicating that a patient is symptomatic but in bed less than 50% of the day."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002363, owl:NamedIndividual ;
    rdfs:label "60-70: symptomatic but in bed less than 50% of the day" .

obo:OBI_0002367
    obo:IAO_0000111 "40-50: symptomatic, in bed more than 50% of the day, but not bed ridden" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A Karnofsky score vaue specification indicating that a patient is symptomatic, in bed more than 50% of the day, but not bed ridden."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBI"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    a obo:OBI_0002363, owl:NamedIndividual ;
    rdfs:label "40-50: symptomatic, in bed more than 50% of the day, but not bed ridden" .

obo:OBI_0002368
    obo:IAO_0000111 "clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "clinical history of cancer" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002369
    obo:IAO_0000111 "clinical history devoid of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there was no diagnosis of cancer."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "clinical history of no cancer"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "clinical history devoid of cancer" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002370
    obo:IAO_0000111 "unknown clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which it is not known whether there was a diagnosis of cancer."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "unknown clinical history of cancer" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002371
    obo:IAO_0000111 "diagnosis of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has cancer."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "cancer diagnosis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "diagnosis of cancer" ;
    rdfs:subClassOf obo:OGMS_0000073 .

obo:OBI_0002372
    obo:IAO_0000111 "family clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a blood relative."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "family history of cancer"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "family clinical history of cancer" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002373
    obo:IAO_0000111 "aunt clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in the female sibling of a parent."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "aunt clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002374
    obo:IAO_0000111 "brother clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a male sibling."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "brother clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002375
    obo:IAO_0000111 "daughter clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a person's female child."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "daughter clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002376
    obo:IAO_0000111 "father clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a male parent."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "father clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002377
    obo:IAO_0000111 "mother clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a female parent."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "mother clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002378
    obo:IAO_0000111 "sister clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a female sibling."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "sister clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002379
    obo:IAO_0000111 "son clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a person's male child."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "son clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002380
    obo:IAO_0000111 "uncle clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a male sibling of a parent."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "uncle clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002381
    obo:IAO_0000111 "grandmother clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a female parent of a parent."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "grandmother clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002382
    obo:IAO_0000111 "grandfather clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a male parent of a parent."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "grandfather clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002383
    obo:IAO_0000111 "nephew clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a male child of a sibling."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "nephew clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002384
    obo:IAO_0000111 "niece clinical history of cancer" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is a diagnosis of cancer in a female child of a sibling."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "niece clinical history of cancer" ;
    rdfs:subClassOf obo:OBI_0002372 .

obo:OBI_0002385
    obo:IAO_0000111 "diagnosis of infectious disease" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has an infectious disease."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "diagnosis of infectious disease" ;
    rdfs:subClassOf obo:OGMS_0000073 .

obo:OBI_0002386
    obo:IAO_0000111 "diagnosis of hepatitis B" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A diagnosis of infectious disease caused by the hepatitis B virus."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "diagnosis of hepatitis B" ;
    rdfs:subClassOf obo:OBI_0002385 .

obo:OBI_0002387
    obo:IAO_0000111 "diagnosis of hepatitis C" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A diagnosis of infectious disease caused by the hepatitis C virus."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "diagnosis of hepatitis C" ;
    rdfs:subClassOf obo:OBI_0002385 .

obo:OBI_0002388
    obo:IAO_0000111 "diagnosis of HIV" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A diagnosis of infectious disease caused by the human immunodeficiency virus (1 or 2)."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "diagnosis of HIV" ;
    rdfs:subClassOf obo:OBI_0002385 .

obo:OBI_0002389
    obo:IAO_0000111 "clinical history of repeated HIV assays" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there is repeated reactive screening assays for human immunodeficiency virus (1 or 2) antibodies regardless of the results of supplemental assays."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "clinical history of repeated HIV assays" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002390
    obo:IAO_0000111 "exposure to second hand smoke" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which there has been second hand exposure to tobacco smoking. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to second hand smoke" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002391
    obo:IAO_0000111 "exposure to second hand smoke in household during childhood" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exposure to second hand smoke that occurred in the (patient's) household when the person was a child."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to second hand smoke in household during childhood" ;
    rdfs:subClassOf obo:OBI_0002390 .

obo:OBI_0002392
    obo:IAO_0000111 "exposure to second hand smoke in current household" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exposure to second hand smoke in person's current household."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to second hand smoke in current household" ;
    rdfs:subClassOf obo:OBI_0002390 .

obo:OBI_0002393
    obo:IAO_0000111 "pregnancy history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which a female has had a pregnancy."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pregnancy history" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002394
    obo:IAO_0000111 "number of pregnancies" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A measurement datum of the total number of pregnancies a woman has had."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "number of pregnancies" ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0002395
    obo:IAO_0000111 "number of live births" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A measurement datum of the total number of live births a female has had."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "number of live births" ;
    rdfs:subClassOf obo:IAO_0000109 .

obo:OBI_0002396
    obo:IAO_0000111 "age when gave birth to first child" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An age measurement datum performed on a female when her first biological child was born."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age when gave birth to first child" ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0002397
    obo:IAO_0000111 "gynecologic surgery history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which a woman has had gynecologic surgery in the past."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "gynecologic surgery history" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002398
    obo:IAO_0000111 "hysterectomy history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A gynecologic surgery history in which a woman has had a hysterectomy."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "hysterectomy history" ;
    rdfs:subClassOf obo:OBI_0002397 .

obo:OBI_0002399
    obo:IAO_0000111 "unilateral oophorectomy history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A gynecologic surgery history in which a woman has had a unilateral oophorectomy."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "unilateral oophorectomy history" ;
    rdfs:subClassOf obo:OBI_0002397 .

obo:OBI_0002400
    obo:IAO_0000111 "neither hysterectomy nor oophorectomy history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A gynecologic surgery history in which a woman has not had either a hysterectomy or an oophorectomy."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "neither hysterectomy nor oophorectomy history" ;
    rdfs:subClassOf obo:OBI_0002397 .

obo:OBI_0002401
    obo:IAO_0000111 "hormonal birth control use history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An information content entity that indicates whether a woman has ever used oral contraceptives in order to block ovulation and prevent the occurrence of pregnancy."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "hormonal birth control use history" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002402
    obo:IAO_0000111 "hormonal birth control former use history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A hormonal birth control use history that indicates an individual has previously been a hormonal birth control user but is not a current user."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "hormonal birth control former use history" ;
    rdfs:subClassOf obo:OBI_0002401 .

obo:OBI_0002403
    obo:IAO_0000111 "hormonal birth control current use history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A hormonal birth control use history that indicates an individual is currently a hormonal birth control user."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "hormonal birth control current use history" ;
    rdfs:subClassOf obo:OBI_0002401 .

obo:OBI_0002404
    obo:IAO_0000111 "no hormonal birth control use history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A hormonal birth control use history that indicates an individual has not ever been a hormonal birth control user."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "no hormonal birth control use history" ;
    rdfs:subClassOf obo:OBI_0002401 .

obo:OBI_0002405
    obo:IAO_0000111 "hormonal replacement therapy history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A clinical history in which an individual has had hormonal replacement therapy in the past."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "hormonal replacement therapy history" ;
    rdfs:subClassOf obo:OGMS_0000015 .

obo:OBI_0002406
    obo:IAO_0000111 "delivery form for hormonal replacement therapy" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A processed material used for delivery of hormones in hormone replacement therapy."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "form of hormone replacement therapy"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "delivery form for hormonal replacement therapy" ;
    rdfs:subClassOf obo:OBI_0000047 .

obo:OBI_0002407
    obo:IAO_0000111 "pill delivery form for hormonal replacement therapy" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A delivery form for hormonal replacement therapy that is a pill for oral administration."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pill delivery form for hormonal replacement therapy" ;
    rdfs:subClassOf obo:OBI_0002406 .

obo:OBI_0002408
    obo:IAO_0000111 "patch delivery form for hormonal replacement therapy" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A delivery form for hormonal replacement therapy that is a patch for transdermal administration."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "patch delivery form for hormonal replacement therapy" ;
    rdfs:subClassOf obo:OBI_0002406 .

obo:OBI_0002409
    obo:IAO_0000111 "cream delivery form for hormonal replacement therapy" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A delivery form for hormonal replacement therapy that is a cream for transdermal administration."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cream delivery form for hormonal replacement therapy" ;
    rdfs:subClassOf obo:OBI_0002406 .

obo:OBI_0002410
    obo:IAO_0000111 "menopausal status" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An information content entity that indicates the state of a female's cessation of menstruation."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "menopausal status" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002411
    obo:IAO_0000111 "indeterminate menopausal status" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A menopausal status that is neither pre- nor post-menopausal."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "indeterminate menopausal status" ;
    rdfs:subClassOf obo:OBI_0002410 .

obo:OBI_0002412
    obo:IAO_0000111 "premenopausal status" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A menopausal status indicating that less than 6 months has passed since the last menstrual period and there has not been prior bilateral oophorectomy and not on estrogen replacement."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "premenopausal status" ;
    rdfs:subClassOf obo:OBI_0002410 .

obo:OBI_0002413
    obo:IAO_0000111 "perimenopausal status" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A menopausal status indicating that it has been 6-12 months since last menstrual period."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "perimenopausal status" ;
    rdfs:subClassOf obo:OBI_0002410 .

obo:OBI_0002414
    obo:IAO_0000111 "postmenopausal status" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A menopausal status indicating that it has been more than 12 months since the last menstrual period with no prior hysterectomy or that there has been a prior bilateral oophorectomy."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "postmenopausal status" ;
    rdfs:subClassOf obo:OBI_0002410 .

obo:OBI_0002415
    obo:IAO_0000111 "exposure to environmental and workplace carcinogens history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A information content entity that indicates the exposure of an individual to carcinogens in the workplace or environment."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to environmental and workplace carcinogens history" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002416
    obo:IAO_0000111 "exposure to arsenic history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exposure to environmental and workplace carcinogens history where the carcinogen is arsenic."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to arsenic history" ;
    rdfs:subClassOf obo:OBI_0002415 .

obo:OBI_0002417
    obo:IAO_0000111 "exposure to asbestos history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exposure to environmental and workplace carcinogens history where the carcinogen is asbestos."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to asbestos history" ;
    rdfs:subClassOf obo:OBI_0002415 .

obo:OBI_0002418
    obo:IAO_0000111 "exposure to diesel exhaust history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exposure to environmental and workplace carcinogens history where the carcinogen is diesel exhaust."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to diesel exhaust history" ;
    rdfs:subClassOf obo:OBI_0002415 .

obo:OBI_0002419
    obo:IAO_0000111 "exposure to chromium history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exposure to environmental and workplace carcinogens history where the carcinogen is chromium."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to chromium history" ;
    rdfs:subClassOf obo:OBI_0002415 .

obo:OBI_0002420
    obo:IAO_0000111 "exposure to silica history" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exposure to environmental and workplace carcinogens history where the carcinogen is silica."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to silica history" ;
    rdfs:subClassOf obo:OBI_0002415 .

obo:OBI_0002421
    obo:IAO_0000111 "indicator of whether an inclusion criterion was met" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An information content entity that indicates whether or not  an entity has met a specific requirement in order to take part in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "eligibility criterion met"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "indicator of whether an inclusion criterion was met" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002422
    obo:IAO_0000111 "indicator of whether all inclusion criteria were met" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An information content entity  that indicates whether or not  an entity  has met all specific requirements in order to take part in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000118 "all eligibility criteria met"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "indicator of whether all inclusion criteria were met" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002423
    obo:IAO_0000111 "age of majority inclusion criterion" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An inclusion criterion that uses the age of majority for a state or institution, where one is generally considered to be an adult, which if met, makes an individual suitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age of majority inclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002424
    obo:IAO_0000111 "chemotherapy treatment exclusion criterion" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion that defines whether chemotherapy was received or is being received for a previous  or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process"^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "chemotherapy treatment exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002425
    obo:IAO_0000111 "radiation treatment exclusion criteria" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion that defines whether radiation was received or is being received for a previous  or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process"^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "radiation treatment exclusion criteria" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002426
    obo:IAO_0000111 "chemotherapy treatment within the recent past exclusion criterion" ;
    obo:IAO_0000112 "An exclusion criterion defined by the pathologist is defined as whether the individual received chemotherapy within the last two years. "^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion that defines whether chemotherapy was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "chemotherapy treatment within the recent past exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002427
    obo:IAO_0000111 "radiation treatment within the recent past exclusion criterion" ;
    obo:IAO_0000112 "An exclusion criterion defined by the pathologist is defined as whether the individual received  radiation therapy within the last two years. "^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion that defines whether radiation was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "radiation treatment within the recent past exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002428
    obo:IAO_0000111 "BMI range inclusion criterion" ;
    obo:IAO_0000112 "An important inclusion criterion is for for the individual to have a BMI between 18.5 and 35.0"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states a Body Mass Index range, which if met, makes an individual suitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "BMI range inclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002429
    obo:IAO_0000111 "blood transfusion exclusion criterion" ;
    obo:IAO_0000112 "An exclusion criterion that is defined by whether the specimen donor received a whole blood transfusion within 48 hours prior to death."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion that is defined by whether the specimen donor received a whole blood transfusion within a specified time frame prior to death, which if met, makes a specimen donor unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "blood transfusion exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002430
    obo:IAO_0000111 "history of metastatic cancer exclusion criterion" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion defined as whether an individual has ever been diagnosed with metastatic cancer (cancer that spread beyond the initial site such as to other organs like brain bone or liver), which if met, makes the individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "history of metastatic cancer exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002431
    obo:IAO_0000111 "intravenous drug use exclusion criterion" ;
    obo:IAO_0000112 "Donor eligibility based on history of intravenous drug abuse in the last 5 years."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion defined as when an individual has a history of intravenous drug abuse for a specific timeframe, which if met, makes the individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "intravenous drug use exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002432
    obo:IAO_0000111 "history of sex with someone with a history of blood borne infection  exclusion criterion" ;
    obo:IAO_0000112 "Donor eligibility based on whether the donor has a history of sex with someone who has been diagnosed or at risk for HIV/AIDS and/or HCV and/or HBV in the last 5 years."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion defined  as whether an individual has a history of sex with someone who has been diagnosed or at risk for a blood borne infections disease in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "history of sex with someone with a history of blood borne infection  exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002433
    obo:IAO_0000111 "history of sex with someone with a history of intravenous drugs exclusion criterion" ;
    obo:IAO_0000112 "Donor eligibility based on whether the donor has a history of sex with someone who has used intravenous drugs in the last 5 years."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion defined  as whether an individual has a history of sex with someone who has used intravenous drugs in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "history of sex with someone with a history of intravenous drugs exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002434
    obo:IAO_0000111 "HIV exclusion criterion" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion defined  as whether an individual has a history of repeatedly reactive screening assays for HIV-1 or HIV-2 antibody regardless of the results of supplemental assays, which if met, makes the individual unsuitable for a given task or participation in a given process. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "HIV exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002435
    obo:IAO_0000111 "exposure to blood borne infectious disease exclusion criterion" ;
    obo:IAO_0000112 "Donor eligibility based on whether the donor has been exposed to HIV/AIDS. "^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An exclusion criterion defined  as whether an individual has been exposed to a blood borne infections disease through needle sticks and/or contact with non-intact skin and/or contact with open wounds and/or contact with mucous membranes, which if met, makes the individual unsuitable for a given task or participation in a given process."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis"^^xsd:string ;
    obo:IAO_0000119 "NCI BBRB, OBIB"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exposure to blood borne infectious disease exclusion criterion" ;
    rdfs:subClassOf obo:OBI_0500028 .

obo:OBI_0002444
    obo:IAO_0000111 "measurand role"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A role borne by a material entity and realized in an assay which achieves the objective to measure the magnitude/concentration/amount of the measurand in the entity bearing evaluant role." ;
    obo:IAO_0000117 "Person: Alan Ruttenberg, Jie Zheng" ;
    obo:IAO_0000119 "https://en.wiktionary.org/wiki/measurand" ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/778" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "measurand role"@en ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000081 ;
        owl:someValuesFrom obo:BFO_0000040
    ] .

obo:OBI_0002453
    obo:IAO_0000111 "health status inclusion criterion"@en ;
    obo:IAO_0000112 "‘diagnosed with Type 2 diabetes mellitus’, ‘E11.4’, ’not finding of hypertension'"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states one or more clinically significant bodily components, dispositions, and/or bodily processes of an entity that are inferred from relevant clinical findings or self-reported, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000234 "MIABIS2.0"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "health status inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002454
    obo:IAO_0000111 "clinically relevant lifestyle inclusion criterion"@en ;
    obo:IAO_0000112 "'smoking behavior’"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states one or more clinically relevant planned processes that a human being actively participates in , which, if met, makes the human being suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000234 "MIABIS2.0"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "clinically relevant lifestyle inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002455
    obo:IAO_0000111 "clinically relevant exposure inclusion criterion"@en ;
    obo:IAO_0000112 "'exposure to cigarette smoke’, ‘exposure to lead through drinking water'"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states one or more clinically relevant histories of exposure of an entity, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000234 "MIABIS2.0"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "clinically relevant exposure inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002456
    obo:IAO_0000111 "gravidity inclusion criterion"@en ;
    obo:IAO_0000112 "'pregnant’, ‘not pregnant'"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states one or more gravidity statuses of an organism, which, if met, makes the entity suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000234 "MIABIS2.0"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "gravidity inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002460
    obo:IAO_0000111 "defined population inclusion criterion" ;
    obo:IAO_0000112 "inclusion based on age, sex, and living region (rural area or specified city)." ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An inclusion criterion that is based on fitting within the defined characteristics of a population based study design." ;
    obo:IAO_0000117 "Chris Stoeckert, Mathias Brochhausen" ;
    obo:IAO_0000119 "MIABIS 2.0" ;
    obo:IAO_0000233 920 ;
    obo:IAO_0000234 "MIABIS 2.0" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "defined population inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002465
    obo:IAO_0000111 "age since culture seeding measurement datum"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An age measurement datum that is the result of the measurement of the age of a cell since cultured (the process of seeding cells onto a culture dish)." ;
    obo:IAO_0000117 "Stephen A. Fisher, Junhyong Kim, Dan Berrios" ;
    obo:IAO_0000118 "age of culture" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age since culture seeding measurement datum" ;
    rdfs:subClassOf obo:OBI_0001167 .

obo:OBI_0002500
    obo:IAO_0000111 "amniotic fluid specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from amniotic fluid."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "amniotic fluid specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000173
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002501
    obo:IAO_0000111 "bile specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from bile."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "bile specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001970
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002502
    obo:IAO_0000111 "cerebrospinal fluid specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from cerbrospinal fluid."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cerebrospinal fluid specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001359
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002503
    obo:IAO_0000111 "feces specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from feces."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "stool specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "feces specimen" ;
    rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002504
    obo:IAO_0000111 "digestive system fluid or secretion specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from digestive system fluid or secretion."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "gastric fluid specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "digestive system fluid or secretion specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0006911
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002505
    obo:IAO_0000111 "milk specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from milk."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "milk specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001913
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002506
    obo:IAO_0000111 "pericardial fluid specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from pericardial fluid."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pericardial fluid specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002409
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002507
    obo:IAO_0000111 "saliva specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from saliva."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "saliva specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001836
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002508
    obo:IAO_0000111 "sputum specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from sputum."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "sputum specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0007311
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002509
    obo:IAO_0000111 "sweat specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from sweat."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "sweat specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001089
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002510
    obo:IAO_0000111 "synovial fluid specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from synovial fluid."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "synovial fluid specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001090
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002511
    obo:IAO_0000111 "vitreous humor specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from vireous humor."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "vitreous fluid specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "vitreous humor specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001797
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002512
    obo:IAO_0000111 "bone marrow specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from bone marrow."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "bone marrow specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002371
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002513
    obo:IAO_0000111 "placenta specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from placenta."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "placenta specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001987
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002514
    obo:IAO_0000111 "peritoneal fluid specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from peritoneal fluid."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "peritoneal fluid specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001268
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002515
    obo:IAO_0000111 "pleural fluid specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from pleural fluid."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, Penn Medicine Biobank"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pleural fluid specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001087
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002516
    obo:IAO_0000111 "brain specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from brain."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "brain specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000955
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002517
    obo:IAO_0000111 "hair specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from hair."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "hair specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001037
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002518
    obo:IAO_0000111 "prostate gland specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from prostate gland."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "prostate gland specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002367
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002519
    obo:IAO_0000111 "skeletal muscle tissue specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from skeletal muscle."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "skeletal muscle tissue specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001134
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002520
    obo:IAO_0000111 "heart specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from heart."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "heart specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000948
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002521
    obo:IAO_0000111 "renal medulla specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from renal medulla."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "kidney medulla specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "renal medulla specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000362
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002522
    obo:IAO_0000111 "adrenal gland specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from adrenal gland."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "adrenal gland specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002369
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002523
    obo:IAO_0000111 "breast specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from breast. "^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "mammary tissue specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "breast specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000310
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002524
    obo:IAO_0000111 "urinary bladder specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from urinary bladder."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "urinary bladder specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001255
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002525
    obo:IAO_0000111 "tibial artery specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from tibial artery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "tibial artery specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0007610
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002526
    obo:IAO_0000111 "skin of body specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from skin."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "skin specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "skin of body specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002097
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002527
    obo:IAO_0000111 "pancreas specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from pancreas."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pancreas specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001264
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002528
    obo:IAO_0000111 "stomach specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from stomach."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "stomach specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000945
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002529
    obo:IAO_0000111 "pituitary gland specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from pituitary gland."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pituitary gland specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000007
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002530
    obo:IAO_0000111 "adipose tissue specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from adipose tissue."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "adipose tissue specimen" ;
    rdfs:subClassOf obo:OBI_0001479 .

obo:OBI_0002531
    obo:IAO_0000111 "cortex of kidney specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from cortex of kidney."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "kidney cortex specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cortex of kidney specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001225
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002532
    obo:IAO_0000111 "esophagus mucosa specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from esophagus mucosa."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "esophagus mucosa specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002469
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002533
    obo:IAO_0000111 "colon specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from colon."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "colon specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001155
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002534
    obo:IAO_0000111 "lung specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from lung."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "lung specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002048
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002535
    obo:IAO_0000111 "esophagus muscularis mucosa specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from esophagus muscularis mucosa."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "esophagus muscularis specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "esophagus muscularis mucosa specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0004648
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002536
    obo:IAO_0000111 "cerebral cortex specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from cerebral cortex."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "brain cortex specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cerebral cortex specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000956
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002537
    obo:IAO_0000111 "thyroid gland specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from thyroid gland."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "thyroid gland specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002046
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002538
    obo:IAO_0000111 "cerebellum specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from cerebellum."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "brain cerebellum specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cerebellum specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002037
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002539
    obo:IAO_0000111 "tibial nerve specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from tibial nerve."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "tibial nerve specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001323
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002540
    obo:IAO_0000111 "coronary artery specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from coronary artery."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "coronary artery specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001621
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002541
    obo:IAO_0000111 "spleen specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from spleen."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "spleen specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002106
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002542
    obo:IAO_0000111 "aorta specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from aorta."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "aorta specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000947
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002543
    obo:IAO_0000111 "atrial appendage specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from the atrium auricular region."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "atrial appendage specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0006618
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002544
    obo:IAO_0000111 "esophagogastric junction specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from the esophagogastric junction."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "esophagogastric junction specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0007650
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002545
    obo:IAO_0000111 "ileum specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from ileum."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "ileum specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002116
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002546
    obo:IAO_0000111 "liver specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from liver."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "liver specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0002107
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002547
    obo:IAO_0000111 "minor salivary gland specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from minor salivary gland."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "minor salivary gland specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001830
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002548
    obo:IAO_0000111 "omentum specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from omentum."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "omentum specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0003688
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002549
    obo:IAO_0000111 "ovary specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from female gonad."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "ovary specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000992
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002550
    obo:IAO_0000111 "sigmoid colon specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from sigmoid colon."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "sigmoid colon specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001159
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002551
    obo:IAO_0000111 "suprapubic skin specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from suprapubic skin."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "suprapubic skin specimen" ;
    rdfs:subClassOf obo:OBI_0002526 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0036149
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002552
    obo:IAO_0000111 "testis specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from testis."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "testis specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000473
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002553
    obo:IAO_0000111 "uterus specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from uterus."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "uterus specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000995
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002554
    obo:IAO_0000111 "vagina specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is derived from vagina."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, NCI BBRB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "vagina specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000996
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002555
    obo:IAO_0000111 "age group inclusion criterion"@en ;
    obo:IAO_0000112 "\"18-33 years old\""@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states an age bracket which, if met, makes an entity suitable for a given task or participation in a given process." ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000233 "#839" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "age group inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom obo:OBI_0002556
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:BFO_0000051 ;
                owl:someValuesFrom obo:OBI_0002557
            ]
        )
    ] .

obo:OBI_0002556
    obo:IAO_0000111 "minimum age value specification"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A value specifcation that specifies the youngest age when specifying an age range."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "minimum age value specification"@en ;
    rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0002557
    obo:IAO_0000111 "maximum age value specification"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A value specifcation that specifies the oldest age when specifying an age range."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "maximum age value specification"@en ;
    rdfs:subClassOf obo:OBI_0001933 .

obo:OBI_0002558
    obo:IAO_0000111 "use of medication inclusion criterion"@en ;
    obo:IAO_0000112 "\"received at least 2 days of vancomycin\""@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states a a set of medications, which, if used by an entity, makes that entity suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000233 "#840"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "use of medication inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002559
    obo:IAO_0000111 "hospital patient inclusion criterion"@en ;
    obo:IAO_0000112 "\"included hospital patients\""@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion defines that a human being has to be a hospital patient to be suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "hospital patient inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002560
    obo:IAO_0000111 "family status inclusion criterion"@en ;
    obo:IAO_0000112 "\"included married and unmarried patients\", \"included divorced individuals\""@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states one or more family statuses, which, if met, makes a human being suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "family status inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002561
    obo:IAO_0000111 "sex inclusion criterion"@en ;
    obo:IAO_0000112 "\"included males and females\", \"included male patients\""@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states one or more sexes which, if met, makes an entity suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "sex inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002562
    obo:IAO_0000111 "country of residence inclusion criteria"@en ;
    obo:IAO_0000112 "\"include US residents\""@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criterion that defines and states one or more countries of residence which, if met, makes a human being suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "country of residence inclusion criteria"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002563
    obo:IAO_0000111 "ethnicity inclusion criterion"@en ;
    obo:IAO_0000112 "\"include only Hispanic individuals\""@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An inclusion criteria that defines and states one or more ethnicities which, if met, makes an entity suitable for a given task or participation in a given process."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "ethnicity inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500027 .

obo:OBI_0002599
    obo:IAO_0000111 "swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is stored on a swab as the output of a collecting specimen with swab process." ;
    obo:IAO_0000117 "Chris Stoeckert" ;
    obo:IAO_0000119 "OBIB/OBI" ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/910" ;
    obo:IAO_0000234 "OBIB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "swab specimen" ;
    rdfs:subClassOf obo:OBI_0100051 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0002600
    ] .

obo:OBI_0002600
    obo:IAO_0000111 "collecting specimen with swab" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen collection process that uses a swab as the collection device. A swab is an absorbent material (e.g. cotton) on a rod (e.g., wooden stick)." ;
    obo:IAO_0000117 "Chris Stoeckert" ;
    obo:IAO_0000119 "OBIB" ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/910" ;
    obo:IAO_0000234 "OBIB" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "collecting specimen with swab" ;
    rdfs:subClassOf obo:OBI_0000659 .

obo:OBI_0002603
    obo:IAO_0000111 "areolar swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of an areola of a breast."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "areolar swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0002032
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002604
    obo:IAO_0000111 "breast swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of a breast."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "breast swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0000310
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002605
    obo:IAO_0000111 "cheek swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the cheek portion of the inside surface of a mouth."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cheek swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0001567
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002606
    obo:IAO_0000111 "nasopharyngeal swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of a nasopharynx."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "nasopharyngeal swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0001728
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002607
    obo:IAO_0000111 "oral swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the inside surface of a mouth."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "oral swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0000165
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002608
    obo:IAO_0000111 "oropharyngeal swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of a oropharynx."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "oropharyngeal swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0001729
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002609
    obo:IAO_0000111 "rectal swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of a rectum."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "rectal swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0001052
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002610
    obo:IAO_0000111 "tongue swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of a tongue."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "tongue swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0001723
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002611
    obo:IAO_0000111 "vagina swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of a vagina."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "vagina swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:UBERON_0000996
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002612
    obo:IAO_0000111 "fecal swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of a feces."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "stool swab specimen"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "fecal swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_0002613
    obo:IAO_0000111 "environmental swab specimen" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen that is collected with a swab from the surface of an environmenal material."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000119 "Chris Stoeckert, OBIB "^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "environmental swab specimen" ;
    rdfs:subClassOf obo:OBI_0002599 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom [
                            a owl:Class ;
                            owl:intersectionOf (obo:OBI_0002600
                                [
                                    a owl:Restriction ;
                                    owl:onProperty obo:OBI_0000293 ;
                                    owl:someValuesFrom obo:ENVO_00010483
                                ]
                            )
                        ]
                    ]
                )
            ]
        )
    ] .

obo:OBI_0002614
    obo:IAO_0000111 "birth cohort study design" ;
    obo:IAO_0000112 "The LucKi Birth Cohort Study was designed and started in 2006 to follow children from birth into adulthood on a wide range of determinants, disorders, and diseases."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A cohort study design for which the subjects are followed from the time of birth usually including information about gestation and follow up."^^xsd:string ;
    obo:IAO_0000117 "MIABIS"^^xsd:string ;
    obo:IAO_0000119 "MIABIS contributors"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "birth cohort study design" ;
    rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0002615
    obo:IAO_0000111 "disease specific study design" ;
    obo:IAO_0000112 "A study of the symptoms experienced by patients who have been diagnosed with multiple sclerosis employs a disease specific study design."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A study design for which material and information is collected from subjects that have already developed a particular disease."^^xsd:string ;
    obo:IAO_0000117 "MIABIS"^^xsd:string ;
    obo:IAO_0000119 "MIABIS contributors"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "disease specific study design" ;
    rdfs:subClassOf obo:OBI_0500000 .

obo:OBI_0002616
    obo:IAO_0000111 "genealogical record"@en ;
    obo:IAO_0000112 "A family tree is a type of genealogical record."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A document about the family relationships of persons related as members of a domestic group linked through descent from a common ancestor, marriage, or adoption."^^xsd:string ;
    obo:IAO_0000117 "MIABIS"^^xsd:string, "Sarah Bost"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "genealogical record"@en ;
    rdfs:subClassOf obo:IAO_0000310 .

obo:OBI_0002617
    obo:IAO_0000111 "national registry"@en ;
    obo:IAO_0000112 "The Social Security Administration's Death Master File is a national registry in the United States."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An information content entity that contains information about a nationwide group of individuals."^^xsd:string ;
    obo:IAO_0000117 "MIABIS"^^xsd:string, "Sarah Bost"^^xsd:string ;
    obo:IAO_0000119 "MIABIS contributors"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "national registry"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OBI_0002618
    obo:IAO_0000111 "national biomedical registry"@en ;
    obo:IAO_0000112 "The Care Register for Health Care, maintained by the Finnish National Institute for Health and Welfare, is a national biomedical registry."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A national registry that contains information about individuals that was accumulated for a biomedical purpose, such as diagnoses, treatments, or outcomes."^^xsd:string ;
    obo:IAO_0000117 "MIABIS"^^xsd:string, "Sarah Bost"^^xsd:string ;
    obo:IAO_0000119 "MIABIS contributors"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "national biomedical registry"@en ;
    rdfs:subClassOf obo:OBI_0002617 .

obo:OBI_0002650
    obo:IAO_0000111 "biopsy" ;
    obo:IAO_0000112 "Biopsy of a potentially cancerous mole."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A specimen collection that obtains a sample of tissue or cell from a living multicellular organism body for diagnostic purposes by means intended to be minimally invasive."^^xsd:string ;
    obo:IAO_0000117 "Damion Dooley"^^xsd:string, "Nicole Vasilevsky"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Biopsy"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "biopsy" ;
    rdfs:subClassOf obo:OBI_0600005 .

obo:OBI_0002651
    obo:IAO_0000111 "image guided biopsy" ;
    obo:IAO_0000112 "Image-guided needle biopsy allows a doctor to biopsy suspicious areas that aren't readily seen or felt through skin, such as in a prostate gland."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy which uses an imaging procedure to guide a needle biopsy."^^xsd:string ;
    obo:IAO_0000117 "Damion Dooley"^^xsd:string ;
    obo:IAO_0000118 "image guided needle biopsy"^^xsd:string, "image-guided biopsy"^^xsd:string, "imaging guided biopsy"^^xsd:string ;
    obo:IAO_0000119 "https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/biopsy/art-20043922"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "image guided biopsy" ;
    rdfs:subClassOf obo:OBI_0002654 .

obo:OBI_0002652
    obo:IAO_0000111 "computed tomography assisted biopsy" ;
    obo:IAO_0000112 "A CT Guided Biopsy is a procedure performed by a radiologist to obtain a small tissue sample through a needle."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A needle biopsy guided by real-time computed tomography (CT) scan images."^^xsd:string ;
    obo:IAO_0000117 "Damion Dooley"^^xsd:string ;
    obo:IAO_0000118 "CT Assisted Biopsy"^^xsd:string, "CT Guided Biopsy"^^xsd:string, "Computed Tomography Assisted Biopsy"^^xsd:string, "Computed Tomography-Guided Needle Biopsy"^^xsd:string ;
    obo:IAO_0000119 "http://purl.obolibrary.org/obo/NCIT_C137909"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "computed tomography assisted biopsy" ;
    rdfs:subClassOf obo:OBI_0002651, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0000982
    ] .

obo:OBI_0002653
    obo:IAO_0000111 "ultrasound-guided needle biopsy" ;
    obo:IAO_0000112 "An ultrasound-guided needle biopsy uses sound waves to help locate a nodule or abnormality within the thyroid."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A needle biopsy guided by ultrasound visualization."^^xsd:string ;
    obo:IAO_0000117 "Damion Dooley"^^xsd:string ;
    obo:IAO_0000119 "https://www.oncolink.org/cancer-treatment/procedures-diagnostic-tests/biopsy-procedures/ultrasound-guided-needle-biopsy"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "ultrasound-guided needle biopsy" ;
    rdfs:subClassOf obo:OBI_0002651 .

obo:OBI_0002654
    obo:IAO_0000111 "needle biopsy" ;
    obo:IAO_0000112 "A needle biopsy is often used on suspicious breast lumps and enlarged lymph nodes that a doctor can feel through a patient's skin."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy that uses a hollow needle to extract cells."^^xsd:string ;
    obo:IAO_0000117 "Damion Dooley"^^xsd:string ;
    obo:IAO_0000119 "https://www.mayoclinic.org/tests-procedures/needle-biopsy/about/pac-20394749"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "needle biopsy" ;
    rdfs:subClassOf obo:OBI_0002650, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0000436
    ] .

obo:OBI_0002655
    obo:IAO_0000111 "fine needle aspiration biopsy" ;
    obo:IAO_0000112 "A fine needle aspiration biopsy is commonly performed in order to test for cancer."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy that uses a thin needle to extract cells."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "FNA"^^xsd:string, "FNAB"^^xsd:string ;
    obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769667/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "fine needle aspiration biopsy" ;
    rdfs:subClassOf obo:OBI_0002654 .

obo:OBI_0002656
    obo:IAO_0000111 "core needle biopsy" ;
    obo:IAO_0000112 "A core needle biopsy can remove more tissue than a fine needle biopsy, and therefore can provide more information about the cells and tissue removed."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy that uses a hollow tube to collect a core of tissue."^^xsd:string ;
    obo:IAO_0000117 "Chris Stoeckert, Helena Ellis, Jie Zheng"^^xsd:string ;
    obo:IAO_0000118 "CNB"^^xsd:string ;
    obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769667/"^^xsd:string ;
    obo:IAO_0000234 "NCI BBRB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "core needle biopsy" ;
    rdfs:subClassOf obo:OBI_0002654 .

obo:OBI_0002657
    obo:IAO_0000111 "surgical biopsy" ;
    obo:IAO_0000112 "Surgical biopsy may be required to collect hard-to-reach tissue."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy involving a surgical incision into an organism to access the biopsy material."^^xsd:string ;
    obo:IAO_0000117 "Damion Dooley"^^xsd:string ;
    obo:IAO_0000118 "excisional biopsy"^^xsd:string, "open biopsy"^^xsd:string ;
    obo:IAO_0000119 "https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/biopsy/art-20043922"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "surgical biopsy" ;
    rdfs:subClassOf obo:OBI_0002650 .

obo:OBI_0002660
    obo:IAO_0000111 "abdominal wall fat pad biopsy" ;
    obo:IAO_0000112 "The makeup of fat in the abdominal wall can be investigated by fat biopsy."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy involving the collection of a small part of the abdominal wall fat pad."^^xsd:string ;
    obo:IAO_0000117 "Nicole Vasilevsky, Damion Dooley"^^xsd:string ;
    obo:IAO_0000118 "abdominal wall biopsy"^^xsd:string, "fat biopsy"^^xsd:string ;
    obo:IAO_0000119 "https://www.ucsfbenioffchildrens.org/tests/003841.html"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "abdominal wall fat pad biopsy" ;
    rdfs:subClassOf obo:OBI_0002650, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:UBERON_0010414
    ] .

obo:OBI_0002661
    obo:IAO_0000111 "tail biopsy" ;
    obo:IAO_0000112 "A mouse tail biopsy was performed to collect material for DNA extraction."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy involving the collection of the tip of a mamallian tail."^^xsd:string ;
    obo:IAO_0000117 "Nicole Vasilevsky, Damion Dooley"^^xsd:string ;
    obo:IAO_0000118 "snip"^^xsd:string ;
    obo:IAO_0000119 "http://web.jhu.edu/animalcare/policies/Tail%20Biopsy%20of%20Mice.pdf"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "tail biopsy" ;
    rdfs:subClassOf obo:OBI_0002650, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:UBERON_0002415
    ] .

obo:OBI_0002662
    obo:IAO_0000111 "bone marrow biopsy" ;
    obo:IAO_0000112 "A bone marrow biopsy removes bone with the marrow inside to look at under a microscope"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy where a small amount of bone and a small amount of fluid and bone marrow are collected."^^xsd:string ;
    obo:IAO_0000117 "Nicole Vasilevsky"^^xsd:string ;
    obo:IAO_0000119 "http://www.webmd.com/cancer/bone-marrow-aspiration-and-biopsy"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "bone marrow biopsy" ;
    rdfs:subClassOf obo:OBI_0002650, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:UBERON_0002371
    ] .

obo:OBI_0002663
    obo:IAO_0000111 "skinpunch biopsy" ;
    obo:IAO_0000112 "A three or four millimeter punch is used in s skinpunch biopsy proceedure."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy that involves the collection of a cylinder of skin (including epidermis, dermis and superficial fat) using a punch tool."^^xsd:string ;
    obo:IAO_0000117 "Nicole Vasilevsky"^^xsd:string ;
    obo:IAO_0000118 "punch biopsy; skin biopsy"^^xsd:string ;
    obo:IAO_0000119 "http://healthlibrary.epnet.com/GetContent.aspx?token=b93d114e-5009-4f6a-9917-6c594254fcc7&chunkiid=14861"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "skinpunch biopsy" ;
    rdfs:subClassOf obo:OBI_0002650, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:UBERON_0002199
    ] .

obo:OBI_0002679
    obo:IAO_0000111 "vacuum-assisted biopsy needle"^^xsd:string ;
    obo:IAO_0000112 "Vacuum-assisted biopsy needles come in two varieties: a non-tethered design and a needle design requiring tethering cable to a vacuum source."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000428 ;
    obo:IAO_0000115 "A core biopsy needle integrated with a vacuum system which facilitates the collection of specimen material."^^xsd:string ;
    obo:IAO_0000117 "Damion Dooley"^^xsd:string ;
    obo:IAO_0000119 "https://www.researchgate.net/publication/330227873"^^xsd:string ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/1163"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "vacuum-assisted biopsy needle"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000436, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000383
    ] .

obo:OBI_0002743
    obo:IAO_0000111 "molecular label role"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay."@en ;
    obo:IAO_0000116 """MHB (9-29-13): 'molecular label role' imported from the Reagent Ontology and replaced OBI:OBI_0000140 (label role).
JZ (3-30-20): discussed on the OBI call. Since the REO was never actually registered, we decided to adopt the term into OBI and replaced REO_0000171 by newly assigned ID: OBI:0002743.""" ;
    obo:IAO_0000117 "Group: OBI"@en ;
    obo:IAO_0000118 "molecular tracer role"@en ;
    obo:IAO_0000119 "OBI developer call, 3-12-12" ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/1135"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "molecular label role"@en ;
    rdfs:subClassOf obo:OBI_0000086 .

obo:OBI_0002744
    obo:IAO_0000111 "molecular label"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay"@en ;
    obo:IAO_0000116 "JZ (3-30-20): discussed on the OBI call. Since the REO was never actually registered, we decided to adopt the term into OBI and replaced OBI:0002744 by newly assigned ID: OBI:0002744."@en ;
    obo:IAO_0000117 "Group: OBI"@en ;
    obo:IAO_0000118 "molecular tracer"@en ;
    obo:IAO_0000119 "OBI developer call, 3-12-12" ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/1135"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "molecular label"@en ;
    rdfs:subClassOf obo:CHEBI_23367, obo:OBI_0001879 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:CHEBI_23367
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0002743
            ]
        )
    ] .

obo:OBI_0002745
    obo:IAO_0000111 "vacuum-assisted biopsy" ;
    obo:IAO_0000112 "A vacuum assisted biopsy can remove an area of abnormal cells from breast tissue."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A biopsy performed with a needle augmented with a vacuum device."^^xsd:string ;
    obo:IAO_0000117 "Damion Dooley"^^xsd:string ;
    obo:IAO_0000118 "VAB"^^xsd:string ;
    obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769667/"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "vacuum-assisted biopsy" ;
    rdfs:subClassOf obo:OBI_0002654, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0002679
    ] .

obo:OBI_0002746
    obo:IAO_0000111 "induced sputum specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A sputum specimen that is collected from an organism following its inhalation of a nebulized salt solution."^^xsd:string ;
    obo:IAO_0000117 "John Judkins"^^xsd:string ;
    obo:IAO_0000119 "PMC3297553"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "induced sputum specimen" ;
    rdfs:subClassOf obo:OBI_0002508, [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0100051
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom obo:OBI_0600005
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0001000 ;
                owl:someValuesFrom obo:UBERON_0007311
            ]
        )
    ] .

obo:OBI_0002755
    obo:IAO_0000111 "Oxford Nanopore Technologies"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "An organization that is developing and selling nanopore sequencing products and is based in the UK."^^xsd:string ;
    obo:IAO_0000117 "James A. Overton"^^xsd:string ;
    obo:IAO_0000119 "https://en.wikipedia.org/wiki/Oxford_Nanopore_Technologies"^^xsd:string ;
    a obo:OBI_0000835, owl:NamedIndividual ;
    rdfs:label "Oxford Nanopore Technologies"^^xsd:string .

obo:OBI_0002774
    obo:IAO_0000111 "platelet-poor plasma specimen"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A blood plasma specimen that is the output of some platelet-poor plasma preparation and is the portion of plasma that contains fewer than 10,000 platelets per microliter."@en ;
    obo:IAO_0000117 "PERSON: Matthew Diller"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "platelet-poor plasma specimen"@en ;
    rdfs:subClassOf obo:OBI_0100016 .

obo:OBI_0002775
    obo:IAO_0000111 "platelet-poor plasma preparation process"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A material component separation process in which (1) whole blood is first centrifuged to separate red blood cells from blood plasma, which forms the supernatant, and (2) the blood plasma is then centrifuged to separate platelets from the plasm."@en ;
    obo:IAO_0000117 "PERSON: Matthew Diller"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "platelet-poor plasma preparation process"@en ;
    rdfs:subClassOf obo:OBI_0600014 .

obo:OBI_0002989
    obo:IAO_0000111 "material supplier" ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A person or organization that provides material supplies to other people or organizations." ;
    obo:IAO_0000117 "Rebecca Jackson" ;
    obo:IAO_0000233 "https://github.com/obi-ontology/obi/issues/1289" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material supplier" ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:unionOf (obo:NCBITaxon_9606
                    obo:OBI_0000245
                )
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000018
            ]
        )
    ] .

obo:OBI_0100016
    obo:IAO_0000111 "blood plasma specimen"@en ;
    obo:IAO_0000112 "PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended."@en ;
    obo:IAO_0000116 "03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA."@en ;
    obo:IAO_0000117 "PERSON: Maura Gasparetto"@en, "PERSON: Melanie Courtot"@en, "PERSON: Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000118 "plasma"@en ;
    obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Blood_plasma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "blood plasma specimen"@en ;
    rdfs:subClassOf obo:OBI_0000953 .

obo:OBI_0100017
    obo:IAO_0000111 "blood serum specimen"@en ;
    obo:IAO_0000112 "PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors."@en ;
    obo:IAO_0000117 "PERSON: Maura Gasparetto"@en, "PERSON: Melanie Courtot"@en, "PERSON: Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Blood_plasma"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "blood serum specimen"@en ;
    rdfs:subClassOf obo:OBI_0000953, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf ([
                    a owl:Class ;
                    owl:unionOf (obo:OBI_0302885
                        obo:OBI_0302886
                        obo:OBI_0600052
                    )
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:OBI_0000293 ;
                    owl:someValuesFrom obo:OBI_0000655
                ]
            )
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom obo:OBI_0000112
    ] .

obo:OBI_0100026
    obo:IAO_0000111 "organism"@en ;
    obo:IAO_0000112 "animal"@en, "fungus"@en, "plant"@en, "virus"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ;
    obo:IAO_0000116 "10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')"^^xsd:string, """13-02-2009:
OBI doesn't take position as to  when an organism starts or ends being an organism - e.g. sperm, foetus.
This issue is outside the scope of OBI."""^^xsd:string ;
    obo:IAO_0000117 "GROUP: OBI Biomaterial Branch"^^xsd:string ;
    obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Organism"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "organism"@en ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:OBI_0100051
    obo:IAO_0000111 "specimen"@en ;
    obo:IAO_0000112 "Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A material entity that has the specimen role."@en ;
    obo:IAO_0000116 "Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation."^^xsd:string ;
    obo:IAO_0000117 "PERSON: James Malone"^^xsd:string, "PERSON: Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "GROUP: OBI Biomaterial Branch"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "specimen"@en ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000040
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000087 ;
                owl:someValuesFrom obo:OBI_0000112
            ]
        )
    ] .

obo:OBI_0100060
    obo:IAO_0000111 "cultured cell population"^^xsd:string ;
    obo:IAO_0000112 """A cultured cell population applied in an experiment: \"293 cells expressing TrkA were serum-starved for 18 hours and then neurotrophins were added for 10 min before cell harvest.\"  (Lee, Ramee, et al. \"Regulation of cell survival by secreted proneurotrophins.\" Science 294.5548 (2001): 1945-1948).

A cultured cell population maintained in vitro: \"Rat cortical neurons from 15 day embryos are grown in dissociated cell culture and maintained in vitro for 8–12 weeks\" (Dichter, Marc A. \"Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation.\" Brain Research 149.2 (1978): 279-293).""" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history."^^xsd:string ;
    obo:IAO_0000116 "2013-6-5 MHB: This OBI class was formerly called 'cell culture', but label changed and definition updated following CLO alignment efforts in spring 2013, during which the intent of this class was clarified to refer to portions of a culture or line rather than a complete cell culture or line."@en ;
    obo:IAO_0000117 "PERSON:Matthew Brush"^^xsd:string ;
    obo:IAO_0000118 "cell culture sample" ;
    obo:IAO_0000119 "PERSON:Matthew Brush"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "The extent of a 'cultured cell population' is restricted only in that all cell members must share a propagation history (ie be derived through a common lineage of passages from an initial culture). In being defined in this way, this class can be used to refer to the populations that researchers actually use in the practice of science - ie are the inputs to culturing, experimentation, and sharing. The cells in such populations will be a relatively uniform population as they have experienced similar selective pressures due to their continuous co-propagation. And this population will also have a single passage number, again owing to their common passaging history. Cultured cell populations represent only a collection of cells (ie do not include media, culture dishes, etc), and include populations of cultured unicellular organisms or cultured multicellular organism cells. They can exist under active culture, stored in a quiescent state for future use, or applied experimentally."^^xsd:string ;
    rdfs:label "cultured cell population"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000047, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0600024
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000643 ;
        owl:someValuesFrom obo:CL_0000010
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:CL_0000010 ;
        owl:onProperty obo:OBI_0000643
    ] .

obo:OBI_0100067
    obo:IAO_0000111 "bronchial alveolar lavage"@en ;
    obo:IAO_0000112 "solution containing lung derived T cells, eosinophils, and TNFa."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space."@en ;
    obo:IAO_0000117 "PERSON: Bjoern Peters"@en ;
    obo:IAO_0000118 "BAL"@en ;
    obo:IAO_0000119 "GROUP: IEDB"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "bronchial alveolar lavage"@en ;
    rdfs:subClassOf obo:OBI_0000953, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom obo:OBI_0000112
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:OBI_0600044 ;
        owl:onProperty obo:OBI_0000312
    ] .

obo:OBI_0200000
    obo:IAO_0000111 "data transformation"@en ;
    obo:IAO_0000112 "The application of a clustering protocol to microarray data or the application of a statistical testing method on a primary data set to determine a p-value."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A planned process that produces output data from input data."@en ;
    obo:IAO_0000117 "Elisabetta Manduchi"@en, "Helen Parkinson"@en, "James Malone"@en, "Melanie Courtot"@en, "Philippe Rocca-Serra"^^xsd:string, "Richard Scheuermann"@en, "Ryan Brinkman"@en, "Tina Hernandez-Boussard"@en ;
    obo:IAO_0000118 "data analysis"@en, "data processing"@en ;
    obo:IAO_0000119 "Branch editors"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "data transformation"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000055 ;
        owl:someValuesFrom [
            a owl:Restriction ;
            owl:onProperty obo:RO_0000059 ;
            owl:someValuesFrom [
                a owl:Class ;
                owl:intersectionOf (obo:IAO_0000064
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:BFO_0000051 ;
                        owl:someValuesFrom obo:IAO_0000005
                    ]
                )
            ]
        ]
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:IAO_0000027 ;
        owl:onProperty obo:OBI_0000293
    ] ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0200166
    ] .

obo:OBI_0200166
    obo:IAO_0000111 "data transformation objective"@en ;
    obo:IAO_0000112 "normalize objective"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An objective specification to transformation input data into output data"@en ;
    obo:IAO_0000116 "Modified definition in 2013 Philly OBI workshop" ;
    obo:IAO_0000117 "James Malone"@en ;
    obo:IAO_0000119 "PERSON: James Malone"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "data transformation objective"@en ;
    rdfs:subClassOf obo:IAO_0000005 .

obo:OBI_0200170
    obo:IAO_0000111 "averaging data transformation"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "An averaging data transformation is a data transformation that has objective averaging."@en ;
    obo:IAO_0000117 "James Malone"^^xsd:string ;
    obo:IAO_0000119 "PERSON: James Malone"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "averaging data transformation"@en ;
    rdfs:subClassOf obo:OBI_0200000 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:unionOf ([
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000299 ;
                owl:someValuesFrom obo:OBI_0000679
            ]
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000417 ;
                owl:someValuesFrom obo:OBI_0000425
            ]
        )
    ] .

obo:OBI_0302716
    obo:IAO_0000111 "pool of specimens"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g.  mixing the DNA collected from the individual fish."@en ;
    obo:IAO_0000116 "check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g.  mixing the DNA collected from the individual fish"@en ;
    obo:IAO_0000117 "PERSON: Jennifer Fostel"^^xsd:string ;
    obo:IAO_0000119 "GROUP: CEBS"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pool of specimens"@en ;
    rdfs:subClassOf obo:OBI_0000953 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0100051
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000652
                        [
                            a owl:Restriction ;
                            owl:allValuesFrom obo:OBI_0100051 ;
                            owl:onProperty obo:OBI_0000293
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_0302874
    obo:IAO_0000111 "edited document"^^xsd:string ;
    obo:IAO_0000112 "The OBI manuscript is (much) edited imformation"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A document which is the output of a document editing process"^^xsd:string ;
    obo:IAO_0000117 "Person:Bjoern Peters"^^xsd:string, "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "edited document"@en ;
    rdfs:subClassOf obo:IAO_0000310, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0302908
    ] .

obo:OBI_0302884
    obo:IAO_0000111 "extraction"^^xsd:string ;
    obo:IAO_0000112 "nucleic acid extraction using phenol chloroform"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "A material separation in which a desired component of an input material is separated from the remainder"^^xsd:string ;
    obo:IAO_0000116 """Current the output of material processing defined as the molecular entity, main component in the output material entity, rather than the material entity that have grain molecular entity. 
'nucleic acid extract' is the output of 'nucleic acid extraction' and has grain 'nucleic acid'. However, the output of 'nucleic acid extraction' is 'nucleic acid' rather than 'nucleic acid extract'. We are aware of this issue and will work it out in the future."""@en ;
    obo:IAO_0000117 "Person:Bjoern Peters"^^xsd:string, "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "extraction"@en ;
    rdfs:subClassOf obo:OBI_0600014, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000681
    ] .

obo:OBI_0302885
    obo:IAO_0000111 "filtration"^^xsd:string ;
    obo:IAO_0000112 "PMID: 18524968.Filtration of CSF improves isolation of Mycobacteria.J Clin Microbiol. 2008 Jun 4."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "filtration is a process which separates components suspended in a fluid based on granularity properties relying on a filter device"@en ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "OBI-Branch: adapted from wikipedia and wordnet"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "filtration"@en ;
    rdfs:subClassOf obo:OBI_0600014, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000681
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000057 ;
        owl:someValuesFrom obo:OBI_0000151
    ] .

obo:OBI_0302886
    obo:IAO_0000111 "centrifugation"^^xsd:string ;
    obo:IAO_0000112 "PMID: 18428461.Purification of oligodendrocytes and their progenitors using immunomagnetic separation and Percoll gradient centrifugation. Curr Protoc Neurosci. 2001 May;Chapter 3:Unit 3.12."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation"@en ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "adapted from http://www.fao.org/DOCREP/003/X3910E/X3910E06.htm"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "centrifugation"@en ;
    rdfs:subClassOf obo:OBI_0600014, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000681
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000057 ;
        owl:someValuesFrom obo:OBI_0400106
    ] .

obo:OBI_0302887
    obo:IAO_0000111 "staining"^^xsd:string ;
    obo:IAO_0000112 "PMID: 18540298. Role of modified bleach method in staining of acid-fast bacilli in lymph node aspirates. Acta Cytol. 2008 May-Jun;52(3):325-8."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "Staining is a process which results in the addition a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound."@en ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "adapted from Wikipedia: http://en.wikipedia.org/wiki/Staining"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "staining"@en ;
    rdfs:subClassOf obo:OBI_0000094 .

obo:OBI_0302893
    obo:IAO_0000111 "storage"^^xsd:string ;
    obo:IAO_0000112 "PMID: 18550121.Total Prostate Specific Antigen Stability Confirmed After Long-Term Storage of Serum at -80C. J Urol. 2008 Jun 10."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A maintenance process by which material entities that are not actively metabolizing are placed in well identified location and possibly under controlled environment in ad-hoc devices/structures in order to preserve and protect them from decay/alteration and maintain availability"@en ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "OBI-Branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "storage"@en ;
    rdfs:subClassOf obo:OBI_0000838, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000806
    ] .

obo:OBI_0302908
    obo:IAO_0000111 "document editing"^^xsd:string ;
    obo:IAO_0000112 """Wax DB, Beilin Y, Hossain S, Lin HM, Reich DL.
Manual editing of automatically recorded data in an anesthesia information management system. Anesthesiology. 2008 Nov;109(5):811-5. PMID: 18946292"""@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "is a planned process with specified input original document and specified output edited document"@en ;
    obo:IAO_0000117 "Philippe Rocca-Serra and OBI consortium"^^xsd:string ;
    obo:IAO_0000119 "adapted from wikipedia"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "document editing"@en ;
    rdfs:subClassOf obo:OBI_0000011, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:IAO_0000310
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0302874
    ] .

obo:OBI_0302914
    obo:IAO_0000111 "digital curation"^^xsd:string ;
    obo:IAO_0000112 "PMID: 16901087. Supporting the curation of biological databases with reusable text mining.Genome Inform. 2005;16(2):32-44."@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "Digital curation is the process of establishing and developing long term repositories of digital assets for current and future reference by researchers, scientists, and historians, and scholars generally."@en ;
    obo:IAO_0000117 "Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "wikipedia"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "digital curation"@en ;
    rdfs:subClassOf obo:IAO_0000572 .

obo:OBI_0400106
    obo:IAO_0000111 "centrifuge"^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A device with a rapidly rotating container that applies centrifugal force to its contents"^^xsd:string ;
    obo:IAO_0000117 "Melanie Courtot"^^xsd:string, "Person: Jennifer Fostel"^^xsd:string, "Trish Whetzel"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Centrifuge"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "centrifuge"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000832, obo:OBI_0000932, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Restriction ;
            owl:onProperty obo:RO_0000085 ;
            owl:someValuesFrom obo:OBI_0000370
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000453
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0000372
                [
                    a owl:Restriction ;
                    owl:allValuesFrom obo:OBI_0302886 ;
                    owl:onProperty obo:BFO_0000054
                ]
            )
        ]
    ] .

obo:OBI_0400168
    obo:IAO_0000111 "microtome"^^xsd:string ;
    obo:IAO_0000112 "PMID: 9974145.Serial sectioning of thick tissue with a novel vibrating blade microtome. Brain Res Brain Res Protoc. 1999 Jan;3(3):302-7."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A microtome is a mechanical instrument used to cut biological specimens into very thin segments for further treatment (e.g. ISH) and ultimately microscopic or histologic examination. Most microtomes provide cooling facilities (cryo-microtome) and use a steel blade to cut a slice of defined thickness. Some are automatic, and some are driven by hand."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Phillippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "PERSON: Daniel Schober"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "microtome"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000932, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000372
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000085 ;
        owl:someValuesFrom obo:OBI_0000379
    ] .

obo:OBI_0500000
    obo:IAO_0000111 "study design"@en ;
    obo:IAO_0000112 "a matched pairs study design describes criteria by which subjects are identified as pairs which then undergo the same protocols, and the data generated is analyzed by comparing the differences between the paired subjects, which constitute the results of the executed study design."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution."^^xsd:string ;
    obo:IAO_0000116 "Editor note: there is at least an implicit restriction on the kind of data transformations that can be done based on the measured data available."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Chris Stoeckert"^^xsd:string ;
    obo:IAO_0000118 "experimental design"@en ;
    obo:IAO_0000232 "rediscussed at length (MC/JF/BP). 12/9/08). The definition was clarified to differentiate it from protocol."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "study design"@en ;
    rdfs:subClassOf obo:IAO_0000104, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:OBI_0000272
    ] .

obo:OBI_0500026
    obo:IAO_0000111 "eligibility criterion"@en ;
    obo:IAO_0000112 "PMID: 17579629 -Eligibility criteria included: untreated ED-SCLC; age >/=70 and performance status 0-2, or age <70 and PS 3."@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 """an eligibility criterion (rule) is_a selection criterion which 
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process.
"""@en ;
    obo:IAO_0000117 "Person: Philippe Rocca-Serra"@en ;
    obo:IAO_0000118 "eligibility rule"@en ;
    obo:IAO_0000119 "Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "eligibility criterion"@en ;
    rdfs:subClassOf obo:OBI_0001755 .

obo:OBI_0500027
    obo:IAO_0000111 "inclusion criterion"@en ;
    obo:IAO_0000112 "PMID: 23979341-The major inclusion criterion was patients in whom severe cerebral embolism was diagnosed at age 75 or younger (more than 9 in the NIHSS score on day 7 after the onset of stroke) ."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "an inclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study."@en ;
    obo:IAO_0000117 "Person: Philippe Rocca-Serra"@en ;
    obo:IAO_0000118 "inclusion condition"@en, "inclusion rule"@en ;
    obo:IAO_0000119 "Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "inclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500026 .

obo:OBI_0500028
    obo:IAO_0000111 "exclusion rule"@en ;
    obo:IAO_0000112 "PMID: 17600285-Exclusion criteria included the use of any topical ophthalmic or topical oral medication and/or history of ocular or oral surgery within the past six months."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "an exclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study"@en ;
    obo:IAO_0000117 "Person: Philippe Rocca-Serra"@en ;
    obo:IAO_0000119 "Adapted from Clinical Research Glossary Version 4.0 CDICS glossary group"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "exclusion criterion"@en ;
    rdfs:subClassOf obo:OBI_0500026 .

obo:OBI_0600004
    obo:IAO_0000111 "human subject enrollment"@en ;
    obo:IAO_0000112 "enlisting familiy members of HIV patients into a study"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A planned process with the objective to obtain a population of human subjects to participate in an investigation by determining eligibility of subjects and obtaining informed consent."@en ;
    obo:IAO_0000116 "As with group assignment, should the specified output here be an organism which bears a role"^^xsd:string ;
    obo:IAO_0000117 "Bjoern Peters"@en ;
    obo:IAO_0000119 "IEDB"@en ;
    obo:IAO_0000232 "criteria come from plan / clinical trial branch"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "human subject enrollment"@en ;
    rdfs:subClassOf obo:OBI_0001928, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom obo:OBI_0000810
    ], [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000055 ;
        owl:someValuesFrom [
            a owl:Restriction ;
            owl:onProperty obo:RO_0000059 ;
            owl:someValuesFrom obo:OBI_0500026
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:OBI_0000181
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000051 ;
                    owl:someValuesFrom obo:NCBITaxon_9606
                ]
            )
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf ([
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0000181
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:BFO_0000051 ;
                            owl:someValuesFrom obo:NCBITaxon_9606
                        ]
                    )
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000087 ;
                    owl:someValuesFrom obo:OBI_0000097
                ]
            )
        ]
    ] .

obo:OBI_0600005
    obo:IAO_0000111 "collecting specimen from organism"@en ;
    obo:IAO_0000112 "taking a sputum sample from a cancer patient, taking the spleen from a killed mouse, collecting a urine sample from a patient"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation"@en ;
    obo:IAO_0000117 "PERSON:Bjoern Peters"@en ;
    obo:IAO_0000119 "IEDB"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "collecting specimen from organism"@en ;
    rdfs:subClassOf obo:OBI_0000659, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0100026
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0100051
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000684
    ] .

obo:OBI_0600014
    obo:IAO_0000111 "material component separation"@en ;
    obo:IAO_0000112 "Using a cell sorter to separate a mixture of T cells into two fractions; one with surface receptor CD8 and the other lacking the receptor, or purification"@en ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "a material processing in which components of an input material become segregated in space"@en ;
    obo:IAO_0000117 "Bjoern Peters"@en ;
    obo:IAO_0000119 "IEDB"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material component separation"@en ;
    rdfs:subClassOf obo:OBI_0000094, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:BFO_0000040
    ] ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000639
    ] .

obo:OBI_0600016
    obo:IAO_0000111 "pooling specimens"^^xsd:string ;
    obo:IAO_0000112 "http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=104564; Combining spleens of 20 mice, Combining supernatant from a cell culture obtained at different time points"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "physical combination of several instances of like material"@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000118 "sample pooling"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000232 "like' is one of the things that you should be controling for in a well-designed experiment. The instances of material need to have the same class."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "pooling specimens"@en ;
    rdfs:subClassOf obo:OBI_0000652, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0100051
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0302716
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000686
    ], [
        a owl:Restriction ;
        owl:minCardinality "2"^^xsd:nonNegativeInteger ;
        owl:onProperty obo:OBI_0000293
    ] .

obo:OBI_0600018
    obo:IAO_0000111 "material portioning"@en ;
    obo:IAO_0000112 "pouring 50 mL aliquots of fetal calf serum into conical tubes from a 500 mL stock"@en ;
    obo:IAO_0000114 obo:IAO_0000123 ;
    obo:IAO_0000115 "a material processing in which the input substance is partitioned into a number of portions that are similar in composition."@en ;
    obo:IAO_0000117 "PERSON:Bjoern Peters"@en ;
    obo:IAO_0000118 "aliquoting"@en, "apportioning"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "material portioning"@en ;
    rdfs:subClassOf obo:OBI_0600014, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000678
    ] .

obo:OBI_0600024
    obo:IAO_0000111 "maintaining cell culture"@en ;
    obo:IAO_0000112 "When harvesting blood from a human, isolating T cells, and then limited dilution cloning of the cells, the maintaining_cell_culture step comprises all steps after the initial dilution and plating of the cells into culture, e.g. placing the culture into an incubator, changing or adding media, and splitting a cell culture"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "a protocol application in which cells are kept alive in a defined environment outside of an organism.  part of cell_culturing"@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "maintaining cell culture"@en ;
    rdfs:subClassOf obo:OBI_0000838, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0100060
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:OBI_0000079
                obo:OBI_0001912
            )
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0100060
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000806
    ] .

obo:OBI_0600036
    obo:IAO_0000111 "'establishing cell culture'" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line)." ;
    obo:IAO_0000117 "PERSON:Matthew Brush" ;
    obo:IAO_0000119 "PERSON:Matthew Brush" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "A 'cell culture' as used here referes to a new lineage of cells in culture deriving from a single biological source.. New cultures are established through the initial isolation and culturing of cells from an organismal source, or through changes in an existing cell culture or line that result in a new culture with unique characteristics.  This can occur through the passaging/selection of a primary culture into a secondary culture or line, or experimental modifications of an existing cell culture or line such as an immortalization process or other stable genetic modification. This class covers establishment of cultures of either multicellular organism cells or unicellular organisms." ;
    rdfs:label "establishing cell culture" ;
    rdfs:subClassOf obo:OBI_0000094, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:CL_0000000
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0000079
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0100060
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000456
    ] .

obo:OBI_0600037
    obo:IAO_0000111 "cell culture splitting"@en ;
    obo:IAO_0000112 "The act of taking a cell culture of high density, counting the cells, removing part of the cells, and re-seeding a select number of the cells into new flasks with fresh tissue culture media."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing"@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000118 "cell culture passaging"^^xsd:string ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:comment "An active cell culture is typically split when it has grown to confluence in its culture dish.  Cell culture splitting of a cell culture sample results in an increase in its passage number, which measures how long a sample has been propagated in vitro, and therefore how many selective or genetic changes it is likely to have undergone." ;
    rdfs:label "cell culture splitting"@en ;
    rdfs:subClassOf obo:OBI_0600014, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0100060
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0100060
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000678
    ] .

obo:OBI_0600038
    obo:IAO_0000111 "addition of molecular label"@en ;
    obo:IAO_0000112 "The addition of phycoerytherin label to an anti-CD8 antibody, to label all antibodies. The addition of anti-CD8-PE to a population of cells, to label the subpopulation cells that are CD8+."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay"@en ;
    obo:IAO_0000117 "PERSON:Matthew Brush"@en ;
    obo:IAO_0000118 "labeling"^^xsd:string ;
    obo:IAO_0000119 "OBI developer call, 3-12-12"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "addition of molecular label"@en ;
    rdfs:subClassOf obo:OBI_0000094, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_0002744
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBI_1110109
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:OBI_0001936
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000456
    ] .

obo:OBI_0600044
    obo:IAO_0000111 "lavage"@en ;
    obo:IAO_0000112 "the collection of bronchoalveolar lavage fluid (BAL) from the lungs of mice in order to study the cytokines present"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A protocol application to separate cells and/or cellular secretions from an anatomical space by the introduction and removal of fluid"@en ;
    obo:IAO_0000116 "This is not washing, in which case the material of interest is not the resulting fluid"@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "lavage"@en ;
    rdfs:subClassOf obo:OBI_0600005, obo:OBI_0600014, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000639
    ] .

obo:OBI_0600052
    obo:IAO_0000111 "dialysis"@en ;
    obo:IAO_0000112 "the use of a dialysis bag of select pore size to remove salt from collagen isolated from mouse cartilage"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "a protocol application that uses diffusion through a semi-permeable membrane to separate an input material into two fractions of different composition"@en ;
    obo:IAO_0000117 "PERSON:Kevin Clancy"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "dialysis"@en ;
    rdfs:subClassOf obo:OBI_0600014, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000417 ;
        owl:someValuesFrom obo:OBI_0000681
    ] .

obo:OBI_0666666
    obo:IAO_0000111 "RNA extraction"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "A RNA extraction is a nucleic acid extraction where the desired output material is RNA"@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000232 "requested by Helen Parkinson for MO"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "RNA extraction"@en ;
    rdfs:subClassOf obo:OBI_0666667, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:CHEBI_33697
    ] .

obo:OBI_0666667
    obo:IAO_0000111 "nucleic acid extraction"@en ;
    obo:IAO_0000112 "Phenol / chlorophorm extraction disolvation of protein content folllowed by ethanol precipitation of the nucleic acid fraction over night in the fridge followed by centrifugation to obtain a nucleic acid pellet."@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "a material separation to recover the nucleic acid fraction of an input material"@en ;
    obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ;
    obo:IAO_0000119 "OBI branch derived"@en ;
    obo:IAO_0000232 "requested by Helen Parkinson for MO. Could be defined class"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "nucleic acid extraction"@en ;
    rdfs:subClassOf obo:OBI_0302884, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:OBI_0000671
                obo:OBI_0100026
                obo:OBI_0100060
            )
        ]
    ], [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000299 ;
        owl:someValuesFrom obo:CHEBI_33696
    ] .

obo:OBI_1000024
    obo:IAO_0000111 "cell pellet"@en ;
    obo:IAO_0000112 "Detection of fetal DNA in a cell pellet after centrifugation of mountant. J Forensic Sci. 2003 Jan;48(1):135-6. PMID: 12570214"@en ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A material entity which results from the aggregation of cells produced by the application of centrifugal force to a liquid containing cells in suspension"@en ;
    obo:IAO_0000117 "PERSON: Helen Parkinson"@en, "PERSON: Philippe Rocca-Serra"^^xsd:string ;
    obo:IAO_0000119 "GROUP: CEBS"@en, "GROUP: OBI Biomaterial Branch"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cell pellet"@en ;
    rdfs:subClassOf obo:OBI_0000047, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000312 ;
        owl:someValuesFrom obo:OBI_0302886
    ], [
        a owl:Restriction ;
        owl:onProperty obo:RO_0001000 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:OBI_0100060
                obo:OBI_0100067
            )
        ]
    ] .

obo:OBI_1110087
    obo:IAO_0000111 "donor"^^xsd:string ;
    obo:IAO_0000112 "A T cell line from a PPD(+) donor."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A role which inheres in an organism or part thereof from which any part including cell, organ or tissue is removed with the intention that the donated part will be placed into another organism and/or cultured in vitro."@en ;
    obo:IAO_0000117 "IEDB"@en ;
    obo:IAO_0000118 "donor role"^^xsd:string ;
    obo:IAO_0000119 "IEDB"@en ;
    obo:IAO_0000232 "Definition modified by HP to deal with the case where an organ may be removed for donation but is not transplanted as intended."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "donor"@en ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OBI_1110109
    obo:IAO_0000111 "target of material addition"^^xsd:string ;
    obo:IAO_0000112 "A cell culture into which a mixture of peptides is being added."^^xsd:string ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "A material entity into which another is being added in a material combinatino process"^^xsd:string ;
    obo:IAO_0000116 "10/26/09: This defined class is used as a 'macro' to reduce the size of the IEDB export."^^xsd:string ;
    obo:IAO_0000119 "IEDB"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "target of material addition"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000040 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000087 ;
        owl:someValuesFrom obo:OBI_0000444
    ] .

obo:OBI_1200000
    obo:IAO_0000111 "FFPE specimen" ;
    obo:IAO_0000112 """Many of today’s researchers prefer to use Formalin-Fixed Paraffin-Embedded samples of tissues for their IHC, histological or in-situ genomic analyses. Professionally fixed and embedded FFPE samples and the biomolecules they contain are reasonably stable at ambient temperatures.

-based on https://lab-ally.com/histopathology-resources/ffpe-samples/""" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that has been fixed in formalin and embedded in paraffin." ;
    obo:IAO_0000117 "MIABIS" ;
    obo:IAO_0000118 "formalin-fixed paraffin-embeded specimen" ;
    obo:IAO_0000119 <https://www.biochain.com/general/what-is-ffpe-tissue/> ;
    obo:IAO_0000233 <https://github.com/obi-ontology/obi/issues/1019> ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "FFPE specimen" ;
    rdfs:subClassOf obo:OBI_0000950 .

obo:OBI_2000000
    obo:IAO_0000111 "uterine cervix specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some uterine cervix "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "uterine cervix specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000002
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000001
    obo:IAO_0000111 "urethra specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some urethra "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "urethra specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000057
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000002
    obo:IAO_0000111 "cervical mucus specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some cervical mucus "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "cervical mucus specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000316
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000003
    obo:IAO_0000111 "throat specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some throat "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "throat specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000341
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000004
    obo:IAO_0000111 "eye specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some eye "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "eye specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0000970
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000005
    obo:IAO_0000111 "respiratory system specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some respiratory system "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "respiratory system specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001004
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000006
    obo:IAO_0000111 "upper respiratory tract specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some upper respiratory tract "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "upper respiratory tract specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001557
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000007
    obo:IAO_0000111 "nasopharynx specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some nasopharynx "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "nasopharynx specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001728
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000008
    obo:IAO_0000111 "semen specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some semen"^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "semen specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0001968
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000009
    obo:IAO_0000111 "bodily fluid specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some bodily fluid"^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "bodily fluid specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0006314
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000010
    obo:IAO_0000111 "chorionic villus specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some chorionic villus "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "chorionic villus specimen" ;
    rdfs:subClassOf obo:OBI_0001479 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0007106
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000011
    obo:IAO_0000111 "meconium specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some meconium "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "meconium specimen" ;
    rdfs:subClassOf obo:OBI_0002503 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0007109
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000012
    obo:IAO_0000111 "umbilical cord blood specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some umbilical cord blood"^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "umbilical cord blood specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0012168
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000013
    obo:IAO_0000111 "arterial blood specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some arterial blood"^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "arterial blood specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0013755
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000014
    obo:IAO_0000111 "venous blood specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some venous blood"^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "venous blood specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0013756
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000015
    obo:IAO_0000111 "capillary blood specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some capillary blood"^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "capillary blood specimen" ;
    rdfs:subClassOf obo:OBI_2000009 ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:intersectionOf (obo:OBI_0100051
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:OBI_0000312 ;
                        owl:someValuesFrom obo:OBI_0600005
                    ]
                    [
                        a owl:Restriction ;
                        owl:onProperty obo:RO_0001000 ;
                        owl:someValuesFrom obo:UBERON_0013757
                    ]
                )
            ]
        )
    ] .

obo:OBI_2000016
    obo:IAO_0000111 "erythrocyte specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some erythrocytes"^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "erythrocyte specimen" ;
    rdfs:subClassOf obo:OBI_0002599 .

obo:OBI_2000017
    obo:IAO_0000111 "reticulocyte specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some reticulocytes "^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "reticulocyte specimen" ;
    rdfs:subClassOf obo:OBI_0002599, [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0100051
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0002600
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000293 ;
                            owl:someValuesFrom obo:CL_0000558
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_2000018
    obo:IAO_0000111 "leukocyte specimen" ;
    obo:IAO_0000114 obo:IAO_0000120 ;
    obo:IAO_0000115 "A specimen that is derived from some leukocytes"^^xsd:string ;
    obo:IAO_0000117 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000119 "Christian Stoeckert ORCID:0000-0002-5714-991X"^^xsd:string, "Mark A. Miller ORCID:0000-0001-9076-6066"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/obi.owl> ;
    a owl:Class ;
    rdfs:label "leukocyte specimen" ;
    rdfs:subClassOf obo:OBI_0002599, [
        a owl:Class ;
        owl:intersectionOf (obo:OBI_0100051
            [
                a owl:Restriction ;
                owl:onProperty obo:OBI_0000312 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:intersectionOf (obo:OBI_0002600
                        [
                            a owl:Restriction ;
                            owl:onProperty obo:OBI_0000293 ;
                            owl:someValuesFrom obo:CL_0000738
                        ]
                    )
                ]
            ]
        )
    ] .

obo:OBI_9991118
    obo:IAO_0000111 "IEDB alternative term" ;
    obo:IAO_0000114 obo:IAO_0000122 ;
    obo:IAO_0000115 "An alternative term used by the IEDB."^^xsd:string ;
    obo:IAO_0000117 "PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters"^^xsd:string ;
    obo:IAO_0000119 "IEDB"^^xsd:string ;
    a owl:AnnotationProperty ;
    rdfs:label "IEDB alternative term" .

obo:OGMS_0000015
    obo:IAO_0000115 "A series of statements representing health-relevant qualities of a patient and of a patient's family."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "clinical history" ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OGMS_0000023
    obo:IAO_0000115 "A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "phenotype" ;
    rdfs:subClassOf obo:BFO_0000019 .

obo:OGMS_0000031
    obo:IAO_0000115 "A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "disease" ;
    rdfs:subClassOf obo:BFO_0000016 .

obo:OGMS_0000045
    obo:IAO_0000115 "A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "disorder" ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:OGMS_0000073
    obo:IAO_0000115 "The representation of a conclusion of a diagnostic process."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "diagnosis" ;
    rdfs:subClassOf obo:IAO_0000027 .

obo:OGMS_0000090
    obo:IAO_0000115 "A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate a disorder, the signs and symptoms of a disorder, or a pathological process"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "treatment" ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OGMS_0000097
    obo:IAO_0000115 "A temporally-connected health care process that has as participants an organization or person realizing the health care provider role and a person realizing the patient role.  The health care provider role and patient are realized during the health care encounter"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "health care encounter" ;
    rdfs:subClassOf obo:BFO_0000015 .

obo:OGMS_0000104
    obo:IAO_0000115 "A health care process that involves the interpretation of a clinical picture from a given patient (input) and the assertion to the effect that the patient has a disease, disorder, or syndrome of a certain type, or none of these (output)."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "diagnostic process" ;
    rdfs:subClassOf obo:OBI_0000011 .

obo:OGMS_0000148
    obo:IAO_0000115 "A role borne by some material entity which can be delivered/administrated into some organism and the role is realized during a clinical treatment process aiming to treat symptoms, signs or diagnosed disease." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ogms.owl> ;
    a owl:Class ;
    rdfs:label "medication role" ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OMIABIS_0000000
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000119 "definition derived from the definition of 'human biobank', based on http://www.ethikrat.org/files/der_opinion_human-biobanks.pdf"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000616 ;
    a owl:Class ;
    rdfs:label "obsolete biobank"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000001
    obo:IAO_0000119 "Deutscher Ethikrat: Human biobanks for research. Opinion. Berlin, 2010. http://www.ethikrat.org/files/der_opinion_human-biobanks.pdf"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000617 ;
    a owl:Class ;
    rdfs:label "obsolete human biobank"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000002
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study contact city"^^xsd:string ;
    obo:IAO_0000119 "true"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000618 ;
    a owl:Class ;
    rdfs:label "obsolete settlement part of address of sample collection or study contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000003
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Name of biobank"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000619 ;
    a owl:Class ;
    rdfs:label "obsolete biobank proper name"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000004
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/ISO_3166-1_alpha-2"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000620 ;
    a owl:Class ;
    rdfs:label "obsolete ISO 3166-1 alpha-2 code"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000005
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank ID"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000621 ;
    a owl:Class ;
    rdfs:label "obsolete biobank idenfier with ISO 3166-1 alpha-2 code"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000006
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study ID"^^xsd:string ;
    a owl:Class ;
    rdfs:label "obsolete sample collection or study identifier"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000007
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study contact country"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000622 ;
    a owl:Class ;
    rdfs:label "obsolete ISO 3166-1 alpha-2 code for sample collection or study contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000008
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000732 ;
    a owl:ObjectProperty ;
    rdfs:label "obsolete owns"^^xsd:string ;
    owl:deprecated true .

obo:OMIABIS_0000009
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000733 ;
    a owl:ObjectProperty ;
    rdfs:label "obsolete administrates"^^xsd:string ;
    owl:deprecated true .

obo:OMIABIS_0000010
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "biobank juristic person"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000623 ;
    a owl:Class ;
    rdfs:label "obsolete biobank organization"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000011
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000624 ;
    a owl:Class ;
    rdfs:label "obsolete contacting"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000012
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000625 ;
    a owl:Class ;
    rdfs:label "obsolete contact role"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000013
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000626 ;
    a owl:Class ;
    rdfs:label "obsolete biobank contact person"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000014
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank contact person"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000627 ;
    a owl:Class ;
    rdfs:label "obsolete name of biobank contact person"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000015
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank contact email"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000628 ;
    a owl:Class ;
    rdfs:label "obsolete email address of biobank contact person"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000016
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000629 ;
    a owl:Class ;
    rdfs:label "obsolete postal address of biobank contact person"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000017
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Department"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000630 ;
    a owl:Class ;
    rdfs:label "obsolete department"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000018
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank contact department"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000631 ;
    a owl:Class ;
    rdfs:label "obsolete department of biobank contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000019
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "uri"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Uniform_resource_locator"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000632 ;
    a owl:Class ;
    rdfs:label "obsolete unique resource locator"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000020
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank URL"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000633 ;
    a owl:Class ;
    rdfs:label "obsolete biobank's unique resource locator"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000021
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Telephone_number"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000634 ;
    a owl:Class ;
    rdfs:label "obsolete telephone number"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000022
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank contact phone"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000635 ;
    a owl:Class ;
    rdfs:label "obsolete telephone number of biobank contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000023
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000636 ;
    a owl:Class ;
    rdfs:label "obsolete post-office box number"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000024
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Post-office_box"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000637 ;
    a owl:Class ;
    rdfs:label "obsolete post-office box"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000025
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study contact phone"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000638 ;
    a owl:Class ;
    rdfs:label "obsolete telephone number of sample collection or study contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000026
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Postal_code"^^xsd:string ;
    obo:IAO_0100001 obo:IAO_0000646 ;
    a owl:Class ;
    rdfs:label "obsolete postal code"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000027
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank contact ZIP"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000639 ;
    a owl:Class ;
    rdfs:label "obsolete postal code of biobank contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000028
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank country code"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000640 ;
    a owl:Class ;
    rdfs:label "obsolete ISO 3166-1 alpha-2 code for biobank contact person"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000029
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000641 ;
    a owl:Class ;
    rdfs:label "obsolete settlement part of address"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000030
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank contact city"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000642 ;
    a owl:Class ;
    rdfs:label "obsolete settlement part of address biobank contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000031
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000643 ;
    a owl:Class ;
    rdfs:label "obsolete intra-settlement specification part of address"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000032
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank contact address"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000644 ;
    a owl:Class ;
    rdfs:label "obsolete intra-settlement specification part of address of biobank contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000033
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Hosted studies"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000645 ;
    a owl:Class ;
    rdfs:label "obsolete hosted study collection"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000034
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000646 ;
    a owl:Class ;
    rdfs:label "obsolete name of hosted study collection"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000035
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study contact email"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000647 ;
    a owl:Class ;
    rdfs:label "obsolete email address of sample collection or study contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000036
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample collection or study description"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000648 ;
    a owl:Class ;
    rdfs:label "obsolete sample collection or study aim description"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000037
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Study name"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000649 ;
    a owl:Class ;
    rdfs:label "obsolete study proper name"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000038
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection Responsible / Principal Investigator"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000650 ;
    a owl:Class ;
    rdfs:label "obsolete name of sample collection responsible or principal investigator"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000039
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study contact person"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000651 ;
    a owl:Class ;
    rdfs:label "obsolete name of sample collection or study contact person"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000040
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study contact department"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000652 ;
    a owl:Class ;
    rdfs:label "obsolete department of sample collection or study contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000041
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000653 ;
    a owl:Class ;
    rdfs:label "obsolete street"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000042
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000734 ;
    a owl:ObjectProperty ;
    rdfs:label "obsolete is contact information about"^^xsd:string ;
    owl:deprecated true .

obo:OMIABIS_0000043
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study contact address"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000654 ;
    a owl:Class ;
    rdfs:label "obsolete intra-settlement specification part of address of sample collection or study contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000044
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Sample Collection/Study contact ZIP"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000655 ;
    a owl:Class ;
    rdfs:label "obsolete postal code for sample collection or study contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000045
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "Biobank country code"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000656 ;
    a owl:Class ;
    rdfs:label "obsolete biobank location ISO 3166-1 alpha-2 code"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000046
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000657 ;
    a owl:Class ;
    rdfs:label "obsolete CTEP organization identifier"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000047
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000658 ;
    a owl:Class ;
    rdfs:label "obsolete biobank identifier with ISO 3166-1 alpha-2 code and CTEP organization identifier"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000048
    obo:IAO_0000119 "Reinach, A. S�mtliche Werke. Texkritische Ausgabe, M�nchen: Philosophia Verlag, 1989, p.189-204."^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000735 ;
    a owl:ObjectProperty ;
    rdfs:label "obsolete is owned by"^^xsd:string ;
    owl:deprecated true .

obo:OMIABIS_0000049
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0000119 "http://www.who.int/transplantation/activities/GlobalGlossaryonDonationTransplantation.pdf"^^xsd:string ;
    a owl:Class ;
    rdfs:label "obsolete bone marrow specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000050
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000659 ;
    a owl:Class ;
    rdfs:label "obsolete fixed tissue specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000051
    obo:IAO_0100001 obo:OBIB_0000660 ;
    a owl:Class ;
    rdfs:label "obsolete fixed tissue block specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000052
    obo:IAO_0100001 obo:OBIB_0000661 ;
    a owl:Class ;
    rdfs:label "obsolete fixed tissue slide specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000053
    obo:IAO_0000119 """http://en.wikipedia.org/wiki/Flash_freezing
"""^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000662 ;
    a owl:Class ;
    rdfs:label "obsolete flash frozen specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000054
    obo:IAO_0100001 obo:OBIB_0000663 ;
    a owl:Class ;
    rdfs:label "obsolete fresh tissue specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000055
    obo:IAO_0100001 obo:OBIB_0000664 ;
    a owl:Class ;
    rdfs:label "obsolete frozen tissue block specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000056
    obo:IAO_0100001 obo:OBIB_0000665 ;
    a owl:Class ;
    rdfs:label "obsolete frozen tissue slide specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000057
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0000119 """http://www.ncbi.nlm.nih.gov/pubmed/11269646
"""^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000666 ;
    a owl:Class ;
    rdfs:label "obsolete microdissected specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000060
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000667 ;
    a owl:Class ;
    rdfs:label "obsolete survey data"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000061
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000668 ;
    a owl:Class ;
    rdfs:label "obsolete sampling specimens for biobank"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000093
    obo:IAO_0100001 obo:OBIB_0000669 ;
    a owl:Class ;
    rdfs:label "obsolete biobank contact role"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000094
    obo:IAO_0100001 obo:OBIB_0000670 ;
    a owl:Class ;
    rdfs:label "obsolete sample collection or study contact role"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000099
    obo:IAO_0100001 obo:OBIB_0000671 ;
    a owl:Class ;
    rdfs:label "obsolete sample collection or study contact person"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000100
    a owl:Class ;
    rdfs:label "obsolete study principle investigator or responsible"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_00001006
    obo:IAO_0100001 obo:OBIB_0000672 ;
    a owl:Class ;
    rdfs:label "obsolete specimen disease state datum"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_00001010
    obo:IAO_0100001 obo:OBIB_0000673 ;
    a owl:Class ;
    rdfs:label "obsolete diseased state specimen datum"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_00001011
    obo:IAO_0100001 obo:OBIB_0000674 ;
    a owl:Class ;
    rdfs:label "obsolete mixed state specimen datum"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_00001012
    obo:IAO_0100001 obo:OBIB_0000675 ;
    a owl:Class ;
    rdfs:label "obsolete normal state specimen datum"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_00001013
    a owl:Class ;
    rdfs:label "obsolete unknown state specimen data"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000911
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Fixation_%28histology%29"^^xsd:string, "http://sharedresources.fhcrc.org/training/tips-about-fixation-and-formalin"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000676 ;
    a owl:Class ;
    rdfs:label "obsolete fixation"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0000912
    obo:IAO_0000112 "The addition of phycoerytherin label to an anti-CD8 antibody, to label all antibodies. The addition of anti-CD8-PE to a population of cells, to label the subpopulation cells that are CD8+."^^xsd:string ;
    obo:IAO_0000117 "PERSON: Matthew Brush"^^xsd:string ;
    obo:IAO_0000118 "labeling"^^xsd:string ;
    obo:IAO_0000119 "OBI developer call, 3-12-12"^^xsd:string ;
    a owl:Class ;
    rdfs:label "obsolete addition of molecular label"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001000
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Martin Fransson"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000677 ;
    a owl:Class ;
    rdfs:label "obsolete age interval information"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001001
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000678 ;
    a owl:Class ;
    rdfs:label "obsolete average age"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001002
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Martin Fransson"^^xsd:string ;
    obo:IAO_0000118 "patient register data"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000679 ;
    a owl:Class ;
    rdfs:label "obsolete patient registry data"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001003
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    a owl:Class ;
    rdfs:label "obsolete survey data"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001004
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000680 ;
    a owl:Class ;
    rdfs:label "obsolete date of data entry"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001005
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000681 ;
    a owl:Class ;
    rdfs:label "obsolete date of data update"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001006
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000682 ;
    a owl:Class ;
    rdfs:label "obsolete end date of sampling for biobank"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001007
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000683 ;
    a owl:Class ;
    rdfs:label "obsolete start date of sampling for biobank"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001008
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "secondary infection, nosocomial infection"^^xsd:string ;
    obo:IAO_0000119 "amended from http://en.wikipedia.org/wiki/Comorbidity"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000684 ;
    a owl:Class ;
    rdfs:label "obsolete comorbidity"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001009
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0000118 "main diagnosis"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000685 ;
    a owl:Class ;
    rdfs:label "obsolete primary diagnosis"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001010
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000686 ;
    a owl:Class ;
    rdfs:label "obsolete count of current sampled human study participant"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001011
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000687 ;
    a owl:Class ;
    rdfs:label "obsolete count of current total human study participant"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001012
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000119 "http://www.improvement.nhs.uk/physiologydiagnostics/documents/WhatisPhysiologicalMeasurement.pdf"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000688 ;
    a owl:Class ;
    rdfs:label "obsolete physiological measurement data"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001013
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000689 ;
    a owl:Class ;
    rdfs:label "obsolete storage temperature setting"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001014
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Omics"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000690 ;
    a owl:Class ;
    rdfs:label "obsolete omics experiment on specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001015
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000691 ;
    a owl:Class ;
    rdfs:label "obsolete number of sampled human study participants objective"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001016
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000692 ;
    a owl:Class ;
    rdfs:label "obsolete number of total human study participant objective"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001017
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000693 ;
    a owl:Class ;
    rdfs:label "obsolete case control study design"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001018
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000694 ;
    a owl:Class ;
    rdfs:label "obsolete cross sectional study design"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001019
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000695 ;
    a owl:Class ;
    rdfs:label "obsolete longitudinal study design"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001020
    obo:IAO_0100001 obo:OBIB_0000696 ;
    a owl:Class ;
    rdfs:label "obsolete cohort study design"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001021
    obo:IAO_0100001 obo:OBIB_0000697 ;
    a owl:Class ;
    rdfs:label "obsolete panel study design"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001022
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000698 ;
    a owl:Class ;
    rdfs:label "obsolete population based study design"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001023
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000699 ;
    a owl:Class ;
    rdfs:label "obsolete quality control study design"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001024
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000700 ;
    a owl:Class ;
    rdfs:label "obsolete twin study design"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001025
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000701 ;
    a owl:Class ;
    rdfs:label "obsolete survey plan specification"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001026
    obo:IAO_0000117 "Martin Fransson"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000702 ;
    a owl:Class ;
    rdfs:label "obsolete medical record"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001027
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000703 ;
    a owl:Class ;
    rdfs:label "obsolete sample medical record"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001028
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000704 ;
    a owl:Class ;
    rdfs:label "obsolete sample handling summary"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001029
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0000118 "sampled group age interval"^^xsd:string ;
    obo:IAO_0000119 """http://www.abta.org/Dictionary/67
"""^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000705 ;
    a owl:Class ;
    rdfs:label "obsolete age interval information for sampled donors"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001031
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000706 ;
    a owl:Class ;
    rdfs:label "obsolete donor patient registry data"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001032
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000707 ;
    a owl:Class ;
    rdfs:label "obsolete study subject survey data"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001033
    obo:IAO_0100001 obo:OBIB_0000708 ;
    a owl:Class ;
    rdfs:label "obsolete sample collection data entry"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001034
    obo:IAO_0100001 obo:OBIB_0000709 ;
    a owl:Class ;
    rdfs:label "obsolete sample collection data update"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001035
    obo:IAO_0100001 obo:OBIB_0000710 ;
    a owl:Class ;
    rdfs:label "obsolete survey execution"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001036
    obo:IAO_0100001 obo:OBIB_0000711 ;
    a owl:Class ;
    rdfs:label "obsolete temperature regulating"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001037
    obo:IAO_0000119 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000712 ;
    a owl:Class ;
    rdfs:label "obsolete comment from tissue procurement"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001038
    obo:IAO_0000112 "3mm X 3mm X 3mm"^^xsd:string ;
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000713 ;
    a owl:Class ;
    rdfs:label "obsolete specimen measurement"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001039
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "date of specimen preparation"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000714 ;
    a owl:Class ;
    rdfs:label "obsolete date of specimen collection"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001040
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "adherance to specification"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000715 ;
    a owl:Class ;
    rdfs:label "obsolete specimen meeting specification"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001041
    obo:IAO_0000112 "mastectomy / craniotomy / liver resection e.t.c."^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Surgery"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000716 ;
    a owl:Class ;
    rdfs:label "obsolete surgical procedure"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001042
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000717 ;
    a owl:Class ;
    rdfs:label "obsolete specimen preparation contact"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001043
    obo:IAO_0000112 "15min"^^xsd:string ;
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000718 ;
    a owl:Class ;
    rdfs:label "obsolete time in formalin measurement"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001044
    obo:IAO_0100001 obo:OBIB_0000719 ;
    a owl:Class ;
    rdfs:label "obsolete specimen surgical removal"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001045
    obo:IAO_0100001 obo:OBIB_0000720 ;
    a owl:Class ;
    rdfs:label "obsolete specimen freezing"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001046
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0000119 "http://biospecimens.cancer.gov/resources/sops/GTEx_SOPs/II/A/GTEx%20Tissue%20Procurement%20SOP%20%28PR-0004%20v1.2.1%29.pdf"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000721 ;
    a owl:Class ;
    rdfs:label "obsolete specimen ID"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001047
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0000119 "http://biospecimens.cancer.gov/resources/sops/GTEx_SOPs/II/A/GTEx%20Tissue%20Procurement%20SOP%20%28PR-0004%20v1.2.1%29.pdf"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000722 ;
    a owl:Class ;
    rdfs:label "obsolete case ID"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001048
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0000119 "http://en.wikipedia.org/wiki/Specification_(technical_standard)"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000723 ;
    a owl:Class ;
    rdfs:label "obsolete specimen measurement specification"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001049
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000724 ;
    a owl:Class ;
    rdfs:label "obsolete time of specimen freezing"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001050
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000725 ;
    a owl:Class ;
    rdfs:label "obsolete time of surgical removal of specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001054
    obo:IAO_0100001 obo:OBIB_0000726 ;
    a owl:Class ;
    rdfs:label "obsolete normal specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001075
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0000119 "http://www.ncbi.nlm.nih.gov/books/NBK398/"^^xsd:string ;
    a owl:Class ;
    rdfs:label "obsolete cerebrospinal fluid specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001076
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    a owl:Class ;
    rdfs:label "obsolete faeces specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001077
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    a owl:Class ;
    rdfs:label "obsolete saliva specimen"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001078
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000727 ;
    a owl:Class ;
    rdfs:label "obsolete hosting biobank"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001079
    obo:IAO_0000117 "Alice Nzinga"^^xsd:string, "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0000118 "sample donor"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000728 ;
    a owl:Class ;
    rdfs:label "obsolete specimen donor"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001080
    obo:IAO_0000118 "specimen handling"^^xsd:string ;
    obo:IAO_0000119 """http://www.exchangenetwork.net/standards/SampleHandling_01_06_2006_Final.pdf
"""^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000729 ;
    a owl:Class ;
    rdfs:label "obsolete sample handling"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001081
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000730 ;
    a owl:Class ;
    rdfs:label "obsolete start of sampling specimens for biobank"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMIABIS_0001082
    obo:IAO_0000117 "Mathias Brochhausen"^^xsd:string ;
    obo:IAO_0100001 obo:OBIB_0000731 ;
    a owl:Class ;
    rdfs:label "obsolete end of sampling specimens for biobank"^^xsd:string ;
    rdfs:subClassOf oboInOwl:ObsoleteClass ;
    owl:deprecated true .

obo:OMRSE_00000010
    obo:IAO_0000115 "A role in human social processes that is realized by health care processes such as seeking or providing treatment for disease and injury, diagnosing disease and injury, or undergoing diagnosis. "@en ;
    obo:IAO_0000117 "William R. Hogan"@en ;
    obo:IAO_0000118 "health care role"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    a owl:Class ;
    rdfs:comment "Mathias Brochhausen" ;
    rdfs:label "human health care role"@en ;
    rdfs:subClassOf obo:OMRSE_00000024, [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000054 ;
        owl:someValuesFrom obo:OGMS_0000097
    ] .

obo:OMRSE_00000012
    obo:IAO_0000115 "A human health care role inhering in an organization or human being that is realized by a process of providing health care services to an organism."@en ;
    obo:IAO_0000117 """Mathias Brochhausen
"""@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    a owl:Class ;
    rdfs:comment "William R. Hogan"@en ;
    rdfs:label "health care provider role"@en ;
    rdfs:subClassOf obo:OMRSE_00000010, obo:OMRSE_00000048, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:RO_0000052 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:unionOf (obo:NCBITaxon_9606
                        obo:OBI_0000245
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:allValuesFrom [
                    a owl:Class ;
                    owl:unionOf (obo:NCBITaxon_9606
                        obo:OBI_0000245
                    )
                ] ;
                owl:onProperty obo:RO_0000052
            ]
        )
    ] .

obo:OMRSE_00000014
    obo:IAO_0000115 "A health care role borne by a human being and realized by the care of individuals, families, and communities so they may attain, maintain, or recover optimal health and quality of life."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000118 "nurse"@en ;
    obo:IAO_0000119 "based on: http://en.wikipedia.org/wiki/Nursing"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    a owl:Class ;
    rdfs:label "nurse role"@en ;
    rdfs:subClassOf obo:OMRSE_00000012, obo:OMRSE_00000050 .

obo:OMRSE_00000023
    obo:IAO_0000115 "An object aggregate all of whose components are human beings."@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl>, "http://purl.obolibrary.org/obo/omrse.owl" ;
    a owl:Class ;
    rdfs:label "collection of humans"@en ;
    rdfs:subClassOf obo:PCO_0000000 .

obo:OMRSE_00000024
    obo:IAO_0000115 "A role inhering in an entity realized by social interactions in human society."@en ;
    obo:IAO_0000117 "Mathias Brochhausen"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl>, "http://purl.obolibrary.org/obo/omrse.owl" ;
    a owl:Class ;
    rdfs:comment "Previous definition: A role played by an entity in human social processes."@en ;
    rdfs:label "role in human social processes"@en ;
    rdfs:subClassOf obo:BFO_0000023 .

obo:OMRSE_00000033
    obo:IAO_0000115 "An aggregate of organizations that have some feature in common, but is not itself an organization."@en, "An object aggregate that is not itself an organization and whose members are only organizations that have some feature in common"@en ;
    obo:IAO_0000117 "William R. Hogan"@en, """William R. Hogan
Amanda Hicks"""@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl>, "http://purl.obolibrary.org/obo/omrse.owl" ;
    a owl:Class ;
    rdfs:comment "It is often convenient to group organizations together that otherwise might not even interact with one another. "@en ;
    rdfs:label "aggregate of organizations"@en ;
    rdfs:subClassOf obo:BFO_0000040, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0002351 ;
        owl:someValuesFrom obo:OBI_0000245
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Class ;
                owl:complementOf obo:OBI_0000245
            ]
            [
                a owl:Restriction ;
                owl:allValuesFrom obo:OBI_0000245 ;
                owl:onProperty obo:RO_0002351
            ]
            [
                a owl:Restriction ;
                owl:minQualifiedCardinality "2"^^xsd:nonNegativeInteger ;
                owl:onClass obo:OBI_0000245 ;
                owl:onProperty obo:RO_0002351
            ]
        )
    ] .

obo:OMRSE_00000038
    obo:IAO_0000115 "A role borne by a human individual or by a collection of humans regarded as possessing rights and duties enforeable at law."@en ;
    obo:IAO_0000117 "Mathias Brochhausen" ;
    obo:IAO_0000119 "Malcolm N. Shaw: International Law. Cambridge University Press, Cambridge, 2008." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    a owl:Class ;
    rdfs:comment """We are aware of the fact that Wikipedia's definition differs from ours by saying that \"Legal personality (...) is the characteristic of a non-living entity regarded by law to have the status of personhood\" (http://en.wikipedia.org/wiki/Legal_personality) 
However, Shaw explicates:
\"In any legal system, certain entities, whether they be individuals or companies, will be regarded as possessing rights and duties enforceable at law. Thus an individual may prosecute or be prosecuted for assault and a company can sue for breach of contract. They are able to do this because the law recognises them as 'legal persons' possessing the capacity to have and to maintain certain rights, and being subject to perform specific duties. (...) In municipal law individuals, limited companies and public corporations are recognized as each possessing a distinct legal personality, the terms of which are circumscribed by the relevant legislation\" (Shaw MN: International Law. Sixth Edition. Cambridge University Press, Cambridge, 2008).                We hold that Shaw's position is ontological more prolific since it not only allows to explain how groups of individuals become recognized as unities at law, but also how different individuals can hold different legal personality roles (always against the context of one legal system). The latter will proof useful when dealing with the representing comatous patients or minorsat law in ontologies."""@en ;
    rdfs:label "legal person role"@en ;
    rdfs:subClassOf obo:OMRSE_00000024, obo:OMRSE_00000048, [
        a owl:Class ;
        owl:intersectionOf ([
                a owl:Restriction ;
                owl:onProperty obo:RO_0000052 ;
                owl:someValuesFrom [
                    a owl:Class ;
                    owl:unionOf (obo:NCBITaxon_9606
                        obo:OMRSE_00000023
                    )
                ]
            ]
            [
                a owl:Restriction ;
                owl:allValuesFrom [
                    a owl:Class ;
                    owl:unionOf (obo:NCBITaxon_9606
                        obo:OMRSE_00000023
                    )
                ] ;
                owl:onProperty obo:RO_0000052
            ]
        )
    ] .

obo:OMRSE_00000048
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    a owl:Class ;
    rdfs:label "material entity role"@en ;
    rdfs:subClassOf obo:BFO_0000023, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom obo:BFO_0000040
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:BFO_0000040 ;
        owl:onProperty obo:RO_0000052
    ] ;
    owl:equivalentClass [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000023
            [
                a owl:Restriction ;
                owl:onProperty obo:RO_0000052 ;
                owl:someValuesFrom obo:BFO_0000040
            ]
        )
    ] .

obo:OMRSE_00000050
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    a owl:Class ;
    rdfs:label "Homo sapiens role"@en ;
    rdfs:subClassOf obo:OMRSE_00000048, [
        a owl:Restriction ;
        owl:onProperty obo:RO_0000052 ;
        owl:someValuesFrom obo:NCBITaxon_9606
    ], [
        a owl:Restriction ;
        owl:allValuesFrom obo:NCBITaxon_9606 ;
        owl:onProperty obo:RO_0000052
    ] .

obo:OMRSE_00000204
    obo:IAO_0000115 "An information content entity that is intended to be a truthful statement about some person and whether that person identifies as some particular aspect of social identity—such as a gender, an ethnicity, a race, or a sexual orientation—where the sense of identifying may correspond to either (i) an aspect of one’s cognitive representation of oneself, (ii) how one prefers to be regarded by others within some social context, or (iii) how one chooses to present oneself to others within some social context."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:comment "We include (i)-(iii) to acknowledge that there are different senses of \"identify\" that are relevant here, and that we may not always be sure which sense the person concretizing the social identity information content entity intended. While (i) concerns how one thinks of oneself, (ii) and (iii) are more focused on one's interactions with others. Importantly, some choose not to share with others how they identify in the sense of (i). For example, one can consider oneself to be some certain gender without either wanting others to know or choosing to present oneself in a corresponding way. We distinguish (ii) and (iii) because one can prefer to be regarded some certain way without attempting to present oneself in any corresponding way."@en ;
    rdfs:label "social identity information content entity"@en ;
    rdfs:subClassOf obo:IAO_0000030 .

obo:OMRSE_00000205
    obo:IAO_0000115 "A social identity information content entity that is about whether some person identifies as some ethnicity."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:comment "Ethnicity is separate from but related to racial identity. It refers more to identifying with a particular culture than with individuals similar in physical appearance. It includes things like Hispanic ethnicity (which spans many nations) and national cultural identities like Irish and ethnic groups within nations such as Catalan and Armenian."@en ;
    rdfs:label "ethnic identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000204 .

obo:OMRSE_00000206
    obo:IAO_0000115 "An ethnic identity information content entity that uses OMB terminology for ethnicity or terminology that is strictly mapped onto the OMB ethnicity terms."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:comment "OMB dichotomizes ethnicity into Hispanic or Latino and Not Hispanic or Latino, and ignores all other forms of ethnicity."@en ;
    rdfs:label "OMB ethnic identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000205 .

obo:OMRSE_00000207
    obo:IAO_0000115 "An OMB ethnic identity information content entity that is about some person's identifying as Hispanic or Latino, which are intended to mean being of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:comment "It comprehends people of Portuguese culture or origin in Brazil."@en ;
    rdfs:label "OMB Hispanic or Latino identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000206 .

obo:OMRSE_00000208
    obo:IAO_0000115 "An OMB ethnic identity information content entity that is about some person's identifying as neither Hispanic nor Latino, which are intended to mean being of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "OMB not Hispanic or Latino identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000206 .

obo:OMRSE_00000209
    obo:IAO_0000115 "A social identity information content entity that is about whether some person identifies as some gender."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "gender identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000204 .

obo:OMRSE_00000210
    obo:IAO_0000115 "A gender identity information content entity that is about some person's identifying as female in gender."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "female gender identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000209 .

obo:OMRSE_00000211
    obo:IAO_0000115 "A gender identity information content entity that is about some person's identifying as male in gender."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "male gender identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000209 .

obo:OMRSE_00000212
    obo:IAO_0000115 "A gender identity information content entity that is about some person's identifying as non-binary in gender."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "non-binary identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000209 .

obo:OMRSE_00000213
    obo:IAO_0000115 "A social identity information content entity that is about whether some person identifies as some race."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "racial identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000204 .

obo:OMRSE_00000214
    obo:IAO_0000115 "A racial identity information content entity that uses OMB terminology and definitions for race or terminology that is strictly mapped onto the OMB race terms."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "OMB racial identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000213 .

obo:OMRSE_00000215
    obo:IAO_0000115 "An OMB racial identity information content entity that is about some person's identifying as American Indian or Alaska Native, which is intended to mean having origins in any of the original peoples of North and South America (including Central America), and maintains tribal affiliation or community attachment."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:comment "This definition corresponds to that used by OMB. It is worth noting that the OMB definition from which this one is derived is problematic, in that it implies that one's race cannot be Native American or Alaskan Native unless one maintains tribal affiliations or community attachment."@en ;
    rdfs:label "OMB American Indian or Alaska Native identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000214 .

obo:OMRSE_00000216
    obo:IAO_0000115 "An OMB racial identity information content entity that is about some person's identifying as Asian, which is intended to mean having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "OMB Asian identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000214 .

obo:OMRSE_00000217
    obo:IAO_0000115 "An OMB racial identity information content entity that is about some person's identifying as black or African American which is intended to mean having origins in any of the black racial groups of Africa."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "OMB black or African American identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000214 .

obo:OMRSE_00000218
    obo:IAO_0000115 "An OMB racial identity information content entity that is about some person's identifying as Native Hawaiian or other Pacific Islander, which is intended to mean having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "OMB Native Hawaiian or other Pacific Islander identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000214 .

obo:OMRSE_00000219
    obo:IAO_0000115 "An OMB racial identity information content entity that is about some person's identifying as white which is intended to mean having origins in any of the original peoples of Europe, the Middle East, or North Africa."@en ;
    obo:IAO_0000117 "S. Clint Dowland"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/omrse.owl> ;
    dc:contributor "Amanda Hicks"@en, "Mathias Brochhausen"@en, "Matthew Diller"@en, "Sarah Bost"@en, "William R. Hogan"@en ;
    a owl:Class ;
    rdfs:label "OMB white identity information content entity"@en ;
    rdfs:subClassOf obo:OMRSE_00000214 .

obo:PATO_0000011
    obo:IAO_0000115 "A time quality inhering in a bearer by virtue of how long the bearer has existed."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "age"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000165 .

obo:PATO_0000047
    obo:IAO_0000115 "An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "biological sex"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001995 .

obo:PATO_0000051
    obo:IAO_0000115 "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "morphology"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001241 .

obo:PATO_0000117
    obo:IAO_0000115 "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "size"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000051 .

obo:PATO_0000119
    obo:IAO_0000115 "A 1-D extent quality inhering in a bearer by virtue of the bearer's vertical dimension of extension."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "height"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001708 .

obo:PATO_0000122
    obo:IAO_0000115 "A 1-D extent quality which is equal to the distance between two points."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "length"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001708 .

obo:PATO_0000125
    obo:IAO_0000115 "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "mass"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001018 .

obo:PATO_0000128
    obo:IAO_0000115 "A physical quality inhering in a bearer that has mass near a gravitational body."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "weight"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001018 .

obo:PATO_0000140
    obo:IAO_0000115 "A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "position"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001018 .

obo:PATO_0000146
    obo:IAO_0000115 "A physical quality of the thermal energy of a system."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "temperature"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001018 .

obo:PATO_0000165
    obo:IAO_0000115 "A quality in which events occur in sequence."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "time"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001018 .

obo:PATO_0000169
    obo:IAO_0000115 "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "viability"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001995 .

obo:PATO_0000918
    obo:IAO_0000115 "A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "volume"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001710 .

obo:PATO_0001018
    obo:IAO_0000115 "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "physical quality"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001241 .

obo:PATO_0001241
    obo:IAO_0000115 "A quality which inheres in a continuant."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "physical object quality"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000019 .

obo:PATO_0001421
    obo:IAO_0000115 "A viability quality inhering in a bearer by virtue of the bearer's condition before death."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "alive"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000169 .

obo:PATO_0001422
    obo:IAO_0000115 "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "dead"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000169 .

obo:PATO_0001442
    obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of whether the bearer includes all its components."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "wholeness"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000051 .

obo:PATO_0001708
    obo:IAO_0000115 "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "1-D extent"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000117 .

obo:PATO_0001710
    obo:IAO_0000115 "A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "3-D extent"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000117 .

obo:PATO_0001985
    obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's being kept below its freezing point."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "frozen"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0000146 .

obo:PATO_0001995
    obo:IAO_0000115 "A quality that inheres in an entire organism or part of an organism."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "organismal quality"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001241 .

obo:PATO_0015009
    obo:IAO_0000115 "A quality inhering in air by virtue of the partial pressure exerted by the bearer's water vapour content."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pato.owl> ;
    a owl:Class ;
    rdfs:label "humidity"^^xsd:string ;
    rdfs:subClassOf obo:PATO_0001018 .

obo:PCO_0000000
    obo:IAO_0000112 "Examples include: population, community, species (meaning the collection of organisms that makes up a species, not the taxonomic rank), and family." ;
    obo:IAO_0000115 "A material entity that consists of two or more organisms, viruses, or viroids."@en ;
    obo:IAO_0000118 "group of organism", "organism collection" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pco.owl> ;
    a owl:Class ;
    rdfs:label "collection of organisms"@en ;
    rdfs:subClassOf obo:BFO_0000027 .

obo:PR_000000001
    obo:IAO_0000115 "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pr.owl> ;
    a owl:Class ;
    rdfs:label "protein"^^xsd:string ;
    rdfs:subClassOf obo:CHEBI_23367 .

obo:PR_000009054
    obo:IAO_0000115 "An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/pr.owl> ;
    a owl:Class ;
    rdfs:label "insulin gene translation product"^^xsd:string ;
    rdfs:subClassOf obo:PR_000000001 .

obo:RO_0000052
    obo:IAO_0000111 "inheres in"@en ;
    obo:IAO_0000112 "this fragility is a characteristic of this vase"@en, "this red color is a characteristic of this apple"@en ;
    obo:IAO_0000115 "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ;
    obo:IAO_0000118 "inheres_in"@en ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:FunctionalProperty, owl:ObjectProperty ;
    rdfs:comment "Note that this relation was previously called \"inheres in\", but was changed to be called \"characteristic of\" because BFO2 uses \"inheres in\" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing." ;
    rdfs:label "characteristic of"@en ;
    owl:inverseOf obo:RO_0000053 .

obo:RO_0000053
    obo:IAO_0000111 "bearer of"@en ;
    obo:IAO_0000112 "this apple is bearer of this red color"@en, "this vase is bearer of this fragility"@en ;
    obo:IAO_0000115 "Inverse of characteristic_of"@en ;
    obo:IAO_0000116 "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist."@en ;
    obo:IAO_0000118 "bearer_of"@en, "is bearer of"@en ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:InverseFunctionalProperty, owl:ObjectProperty ;
    rdfs:label "has characteristic"@en ;
    rdfs:range obo:BFO_0000020 .

obo:RO_0000056
    obo:IAO_0000111 "participates in"@en ;
    obo:IAO_0000112 "this blood clot participates in this blood coagulation"@en, "this input material (or this output material) participates in this process"@en, "this investigator participates in this investigation"@en ;
    obo:IAO_0000115 "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ;
    obo:IAO_0000118 "participates_in"@en ;
    a owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000002 ;
    rdfs:label "participates in"@en ;
    rdfs:range obo:BFO_0000003 ;
    owl:inverseOf obo:RO_0000057 .

obo:RO_0000057
    obo:IAO_0000111 "has participant"@en ;
    obo:IAO_0000112 "this blood coagulation has participant this blood clot"@en, "this investigation has participant this investigator"@en, "this process has participant this input material (or this output material)"@en ;
    obo:IAO_0000115 "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ;
    obo:IAO_0000116 "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."@en ;
    obo:IAO_0000118 "has_participant"@en ;
    dc:source "http://www.obofoundry.org/ro/#OBO_REL:has_participant" ;
    a owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000003 ;
    rdfs:label "has participant"@en ;
    rdfs:range obo:BFO_0000002 .

obo:RO_0000058
    obo:IAO_0000112 "A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant)."@en, "An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process)."@en ;
    obo:IAO_0000115 "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ;
    a owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000031 ;
    rdfs:label "is concretized as"@en ;
    rdfs:range obo:BFO_0000020 ;
    owl:inverseOf obo:RO_0000059 .

obo:RO_0000059
    obo:IAO_0000112 "A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant)."@en, "An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process)."@en ;
    obo:IAO_0000115 "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ;
    a owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000020 ;
    rdfs:label "concretizes"@en ;
    rdfs:range obo:BFO_0000031 .

obo:RO_0000079
    obo:IAO_0000112 "this catalysis function is a function of this enzyme"@en ;
    obo:IAO_0000115 "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ;
    obo:IAO_0000116 "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists."@en ;
    obo:IAO_0000118 "function_of"@en, "is function of"@en ;
    a owl:ObjectProperty ;
    rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ;
    rdfs:domain obo:BFO_0000034 ;
    rdfs:label "function of"@en ;
    rdfs:subPropertyOf obo:RO_0000052 ;
    owl:inverseOf obo:RO_0000085 .

obo:RO_0000080
    obo:IAO_0000112 "this red color is a quality of this apple"@en ;
    obo:IAO_0000115 "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ;
    obo:IAO_0000116 "A quality inheres in its bearer at all times for which the quality exists."@en ;
    obo:IAO_0000118 "is quality of"@en, "quality_of"@en ;
    a owl:ObjectProperty ;
    rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ;
    rdfs:label "quality of"@en ;
    rdfs:subPropertyOf obo:RO_0000052 ;
    owl:inverseOf obo:RO_0000086 .

obo:RO_0000081
    obo:IAO_0000112 "this investigator role is a role of this person"@en ;
    obo:IAO_0000115 "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ;
    obo:IAO_0000116 "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists."@en ;
    obo:IAO_0000118 "is role of"@en, "role_of"@en ;
    a owl:ObjectProperty ;
    rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ;
    rdfs:label "role of"@en ;
    rdfs:subPropertyOf obo:RO_0000052 ;
    owl:inverseOf obo:RO_0000087 .

obo:RO_0000085
    obo:IAO_0000112 "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)"@en ;
    obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ;
    obo:IAO_0000116 "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists."@en ;
    obo:IAO_0000118 "has_function"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000004 ;
    rdfs:label "has function"@en ;
    rdfs:range obo:BFO_0000034 ;
    rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000086
    obo:IAO_0000112 "this apple has quality this red color"@en ;
    obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ;
    obo:IAO_0000116 "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist."@en ;
    obo:IAO_0000118 "has_quality"@en ;
    a owl:ObjectProperty ;
    rdfs:label "has quality"@en ;
    rdfs:range obo:BFO_0000019 ;
    rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000087
    obo:IAO_0000112 "this person has role this investigator role (more colloquially: this person has this role of investigator)"@en ;
    obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ;
    obo:IAO_0000116 "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists."@en ;
    obo:IAO_0000118 "has_role"@en ;
    a owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000004 ;
    rdfs:label "has role"@en ;
    rdfs:range obo:BFO_0000023 ;
    rdfs:subPropertyOf obo:RO_0000053 .

obo:RO_0000091
    obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ;
    a owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000004 ;
    rdfs:label "has disposition"@en ;
    rdfs:range obo:BFO_0000016 ;
    rdfs:subPropertyOf obo:RO_0000053 ;
    owl:inverseOf obo:RO_0000092 .

obo:RO_0000092
    a owl:ObjectProperty ;
    rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ;
    rdfs:label "disposition of"@en ;
    rdfs:subPropertyOf obo:RO_0000052 .

obo:RO_0001000
    obo:IAO_0000112 "this cell derives from this parent cell (cell division)"@en, "this nucleus derives from this parent nucleus (nuclear division)"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
    obo:IAO_0000116 "This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'."@en ;
    obo:IAO_0000118 "derives_from"@en ;
    a owl:ObjectProperty ;
    rdfs:label "derives from"@en ;
    owl:inverseOf obo:RO_0001001 .

obo:RO_0001001
    obo:IAO_0000112 "this parent cell derives into this cell (cell division)"@en, "this parent nucleus derives into this nucleus (nuclear division)"@en ;
    obo:IAO_0000114 obo:IAO_0000125 ;
    obo:IAO_0000115 "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ;
    obo:IAO_0000116 "This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'."@en ;
    obo:IAO_0000118 "derives_into"@en ;
    a owl:ObjectProperty ;
    rdfs:label "derives into"@en .

obo:RO_0001015
    obo:IAO_0000111 "is location of"@en ;
    obo:IAO_0000112 "my head is the location of my brain"@en, "this cage is the location of this rat"@en ;
    obo:IAO_0000115 "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ;
    obo:IAO_0000116 "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en ;
    obo:IAO_0000118 "location_of"@en ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:ObjectProperty, owl:TransitiveProperty ;
    rdfs:label "location of"@en ;
    owl:inverseOf obo:RO_0001025 .

obo:RO_0001025
    obo:IAO_0000111 "located in"@en ;
    obo:IAO_0000112 "my brain is located in my head"@en, "this rat is located in this cage"@en ;
    obo:IAO_0000115 "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ;
    obo:IAO_0000116 "Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1.    Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus"@en, "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en ;
    obo:IAO_0000118 "located_in"@en ;
    obo:RO_0001900 obo:RO_0001901 ;
    dc:source "http://www.obofoundry.org/ro/#OBO_REL:located_in" ;
    a owl:ObjectProperty, owl:TransitiveProperty ;
    rdfs:domain obo:BFO_0000004, [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000004
            [
                a owl:Class ;
                owl:complementOf obo:BFO_0000006
            ]
        )
    ] ;
    rdfs:label "located in"@en ;
    rdfs:range obo:BFO_0000004, [
        a owl:Class ;
        owl:intersectionOf (obo:BFO_0000004
            [
                a owl:Class ;
                owl:complementOf obo:BFO_0000006
            ]
        )
    ] .

obo:RO_0001900
    obo:IAO_0000115 "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ;
    a owl:AnnotationProperty ;
    rdfs:label "temporal interpretation"@en .

obo:RO_0002000
    obo:IAO_0000112 "the surface of my skin is a 2D boundary of my body"@en ;
    obo:IAO_0000115 "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity"@en ;
    obo:IAO_0000116 "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts."@en, "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape."@en ;
    obo:IAO_0000118 "2D_boundary_of"@en, "boundary of"@en, "is 2D boundary of"@en, "is boundary of"@en ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:ObjectProperty ;
    rdfs:label "2D boundary of"@en ;
    owl:inverseOf obo:RO_0002002 .

obo:RO_0002002
    obo:IAO_0000112 "my body has 2D boundary the surface of my skin"@en ;
    obo:IAO_0000115 "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity"@en ;
    obo:IAO_0000116 "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts."@en, "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape."@en ;
    obo:IAO_0000118 "has boundary"@en, "has_2D_boundary"@en ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:ObjectProperty ;
    rdfs:domain obo:BFO_0000040 ;
    rdfs:label "has 2D boundary"@en ;
    rdfs:range obo:BFO_0000141 .

obo:RO_0002180
    obo:IAO_0000115 "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has component"@en ;
    rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002211
    obo:IAO_0000115 "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "regulates"@en ;
    rdfs:subPropertyOf obo:RO_0002411 .

obo:RO_0002212
    obo:IAO_0000115 "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "negatively regulates"@en ;
    rdfs:subPropertyOf obo:RO_0002211, obo:RO_0002305 .

obo:RO_0002222
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "temporally related to"@en .

obo:RO_0002223
    obo:IAO_0000115 "inverse of starts with" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "starts"@en ;
    rdfs:subPropertyOf obo:RO_0002222 .

obo:RO_0002233
    obo:IAO_0000115 "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ;
    obo:IAO_0000118 "consumes" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has input"@en ;
    rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002234
    obo:IAO_0000115 "p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p." ;
    obo:IAO_0000118 "produces" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "has output"@en ;
    rdfs:subPropertyOf obo:RO_0000057 .

obo:RO_0002295
    obo:IAO_0000115 "p results in the developmental progression of s iff p is a developmental process and s is an anatomical structure and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "results in developmental progression of"@en ;
    rdfs:subPropertyOf obo:RO_0002324 .

obo:RO_0002297
    obo:IAO_0000112 "an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists.", "every \"endocardial cushion formation\" (GO:0003272) results_in_formation_of some \"endocardial cushion\" (UBERON:0002062)"@en ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "results in formation of"@en ;
    rdfs:subPropertyOf obo:RO_0002234, obo:RO_0002295 .

obo:RO_0002305
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "causally upstream of, negative effect" ;
    rdfs:subPropertyOf obo:RO_0002411, obo:RO_0004046 .

obo:RO_0002324
    obo:IAO_0000115 "A relationship that holds between entities participating in some developmental process (GO:0032502)" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "developmentally related to"@en .

obo:RO_0002350
    obo:IAO_0000112 "An organism that is a member of a population of organisms" ;
    obo:IAO_0000115 "is member of is a mereological relation between a item and a collection." ;
    obo:IAO_0000118 "is member of", "member part of" ;
    obo:IAO_0000119 "SIO" ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:ObjectProperty ;
    rdfs:label "member of"@en ;
    rdfs:subPropertyOf obo:BFO_0000050 ;
    owl:inverseOf obo:RO_0002351 .

obo:RO_0002351
    obo:IAO_0000115 "has member is a mereological relation between a collection and an item." ;
    obo:IAO_0000119 "SIO" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    obo:RO_0001900 obo:RO_0001901 ;
    a owl:IrreflexiveProperty, owl:ObjectProperty ;
    rdfs:label "has member"@en ;
    rdfs:subPropertyOf obo:BFO_0000051 .

obo:RO_0002352
    obo:IAO_0000115 "inverse of has input" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "input of"@en ;
    rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0002353
    obo:IAO_0000115 "inverse of has output" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "output of"@en ;
    rdfs:subPropertyOf obo:RO_0000056 .

obo:RO_0002410
    obo:IAO_0000115 "This relation groups causal relations between material entities and causal relations between processes" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "causally related to"@en .

obo:RO_0002411
    obo:IAO_0000115 "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "causally upstream of"@en ;
    rdfs:subPropertyOf obo:BFO_0000063, obo:RO_0002418 .

obo:RO_0002416
    obo:IAO_0000115 "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL." ;
    a owl:AnnotationProperty ;
    rdfs:label "logical macro assertion"@en .

obo:RO_0002418
    obo:IAO_0000115 "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q." ;
    obo:IAO_0000118 "influences (processual)" ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "causally upstream of or within" ;
    rdfs:subPropertyOf obo:RO_0002501 .

obo:RO_0002421
    obo:IAO_0000115 "A logical macro assertion whose domain is an IRI for a property" ;
    a owl:AnnotationProperty ;
    rdfs:label "logical macro assertion on a property"@en .

obo:RO_0002422
    obo:IAO_0000115 "Used to annotate object properties to describe a logical meta-property or characteristic of the object property." ;
    a owl:AnnotationProperty ;
    rdfs:label "logical macro assertion on an object property"@en .

obo:RO_0002501
    obo:IAO_0000115 "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q." ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "causal relation between processes" ;
    rdfs:subPropertyOf obo:RO_0002410 .

obo:RO_0004046
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ro.owl> ;
    a owl:ObjectProperty ;
    rdfs:label "causally upstream of or within, negative effect" ;
    rdfs:subPropertyOf obo:RO_0002418 .

obo:RO_0004096
    a owl:ObjectProperty ;
    rdfs:comment "DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information." ;
    rdfs:label "DEPRECATED inheres in"@en ;
    owl:deprecated true ;
    owl:inverseOf obo:RO_0004097 .

obo:RO_0004097
    a owl:ObjectProperty ;
    rdfs:label "DEPRECATED bearer of"@en ;
    owl:deprecated true .

obo:SO_0000001
    obo:IAO_0000115 "A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/so.owl> ;
    a owl:Class ;
    rdfs:label "region"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000031 .

obo:UBERON_0000002
    obo:IAO_0000115 "Lower, narrow portion of the uterus where it joins with the top end of the vagina."^^xsd:string ;
    obo:IAO_0000118 "canalis cervicis uteri"^^xsd:string, "caudal segment of uterus"^^xsd:string, "cervical canal of uterus"^^xsd:string, "cervix uteri"^^xsd:string, "neck of uterus"^^xsd:string, "uterine cervix"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "uterine cervix"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000007
    obo:IAO_0000115 "The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]."^^xsd:string ;
    obo:IAO_0000118 "glandula pituitaria"^^xsd:string, "pituitary"^^xsd:string, "pituitary body"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "pituitary gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000029
    obo:IAO_0000115 "Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "lymph node"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000057
    obo:IAO_0000115 "the fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "urethra"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000059
    obo:IAO_0000115 "A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "large intestine"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0000064
    obo:IAO_0000115 "A multicellular structure that is a part of an organ."^^xsd:string ;
    obo:IAO_0000118 "cardinal organ part"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "organ part"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000165
    obo:IAO_0000115 "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)."^^xsd:string ;
    obo:IAO_0000118 "regio oralis"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "mouth"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000173
    obo:IAO_0000115 "Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "amniotic fluid"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0000178
    obo:IAO_0000115 "A fluid that is composed of blood plasma and erythrocytes."^^xsd:string ;
    obo:IAO_0000118 "portion of blood"^^xsd:string, "vertebrate blood"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "blood"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0000310
    obo:IAO_0000115 "The upper ventral region of the torso of an organism."^^xsd:string ;
    obo:IAO_0000118 "mammary part of chest"^^xsd:string, "mammary region"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "breast"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000316
    obo:IAO_0000115 "A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus."^^xsd:string ;
    obo:IAO_0000118 "cervix mucus"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "cervical mucus"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0000341
    obo:IAO_0000115 "In anatomy, the throat is the anterior part of the neck, in front of the vertebral column. It consists of the pharynx and larynx. An important feature of the throat is the epiglottis, a flap which separates the esophagus from the trachea and prevents inhalation of food or drink. The throat contains various blood vessels, various pharyngeal muscles, the trachea (windpipe) and the esophagus. The hyoid bone and the clavicle are the only bones located in the throat of mammals. It is sometimes considered a synonym for fauces. [WP,unvetted]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "throat"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000362
    obo:IAO_0000115 "the inner portion of the kidney consisting of the renal pyramids"^^xsd:string ;
    obo:IAO_0000118 "kidney medulla"^^xsd:string, "medulla of kidney"^^xsd:string, "medulla renalis"^^xsd:string, "pyramides renales"^^xsd:string, "renal medullae"^^xsd:string, "renal medullae set"^^xsd:string, "renal pyramids"^^xsd:string, "renal pyramids set"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "renal medulla"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000481 .

obo:UBERON_0000463
    obo:IAO_0000115 "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body."^^xsd:string ;
    obo:IAO_0000118 "body fluid or substance"^^xsd:string, "body substance"^^xsd:string, "organism substance"^^xsd:string, "portion of body substance"^^xsd:string, "portion of organism substance"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "organism substance"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000465
    obo:IAO_0000115 "Anatomical entity that has mass."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "material anatomical entity"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0000473
    obo:IAO_0000115 "A gonad of a male animal. A gonad produces and releases sperm."^^xsd:string ;
    obo:IAO_0000118 "gonad of male genitalia"^^xsd:string, "gonad of male reproductive system"^^xsd:string, "male gonad"^^xsd:string, "testicle"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "testis"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000477
    obo:IAO_0000115 "Anatomical group that has its parts adjacent to one another."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "anatomical cluster"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000040 .

obo:UBERON_0000479
    obo:IAO_0000115 "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation."^^xsd:string ;
    obo:IAO_0000118 "portion of tissue"^^xsd:string, "tissue portion"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "tissue"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000481
    obo:IAO_0000115 "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "multi-tissue structure"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000945
    obo:IAO_0000115 "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "stomach"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000947
    obo:IAO_0000115 "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation"^^xsd:string ;
    obo:IAO_0000118 "trunk of aortic tree"^^xsd:string, "trunk of systemic arterial tree"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "aorta"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000948
    obo:IAO_0000115 "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ."^^xsd:string ;
    obo:IAO_0000118 "chambered heart"^^xsd:string, "vertebrate heart"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "heart"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000955
    obo:IAO_0000115 "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "brain"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000956
    obo:IAO_0000115 "The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex."^^xsd:string ;
    obo:IAO_0000118 "cortex of cerebral hemisphere"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "cerebral cortex"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000477 .

obo:UBERON_0000970
    obo:IAO_0000115 "An organ that detects light."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "eye"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000990
    obo:IAO_0000115 "Anatomical system that has as its parts the organs concerned with reproduction."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "reproductive system"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000992
    obo:IAO_0000115 "the gonad of a female organism which contains germ cells"^^xsd:string ;
    obo:IAO_0000118 "animal ovary"^^xsd:string, "female gonad"^^xsd:string, "female organism genitalia gonad"^^xsd:string, "female organism genitalia gonada"^^xsd:string, "female organism reproductive system gonad"^^xsd:string, "female organism reproductive system gonada"^^xsd:string, "female reproductive system gonad"^^xsd:string, "female reproductive system gonada"^^xsd:string, "genitalia of female organism gonad"^^xsd:string, "genitalia of female organism gonada"^^xsd:string, "gonad of female organism genitalia"^^xsd:string, "gonad of female organism reproductive system"^^xsd:string, "gonad of female reproductive system"^^xsd:string, "gonad of genitalia of female organism"^^xsd:string, "gonad of reproductive system of female organism"^^xsd:string, "gonada of female organism genitalia"^^xsd:string, "gonada of female organism reproductive system"^^xsd:string, "gonada of female reproductive system"^^xsd:string, "gonada of genitalia of female organism"^^xsd:string, "gonada of reproductive system of female organism"^^xsd:string, "ovum-producing ovary"^^xsd:string, "reproductive system of female organism gonad"^^xsd:string, "reproductive system of female organism gonada"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "ovary"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0000995
    obo:IAO_0000115 "the female muscular organ of gestation in which the developing embryo or fetus is nourished until birth"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "uterus"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0000996
    obo:IAO_0000115 "A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "vagina"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001004
    obo:IAO_0000115 "Functional system which consists of structures involved in respiration."^^xsd:string ;
    obo:IAO_0000118 "apparatus respiratorius"^^xsd:string, "respiratory system"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "respiratory system"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001013
    obo:IAO_0000115 "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue"^^xsd:string ;
    obo:IAO_0000118 "fat"^^xsd:string, "fat tissue"^^xsd:string, "fatty tissue"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "adipose tissue"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000479 .

obo:UBERON_0001037
    obo:IAO_0000115 "A filament, mostly protein, that grows from follicles found in the dermis[WP]."^^xsd:string ;
    obo:IAO_0000118 "hair"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "strand of hair"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001043
    obo:IAO_0000115 "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)."^^xsd:string ;
    obo:IAO_0000118 "gullet"^^xsd:string, "oesophagus"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "esophagus"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001052
    obo:IAO_0000115 "the terminal portion of the intestinal tube, terminating with the anus"^^xsd:string ;
    obo:IAO_0000118 "terminal portion of intestine"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "rectum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001087
    obo:IAO_0000115 "Transudate contained in the pleural cavity."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "pleural fluid"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0001088
    obo:IAO_0000115 "Excretion that is the output of a kidney"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "urine"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0001089
    obo:IAO_0000115 "Secretion produced by a sweat gland."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "sweat"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0001090
    obo:IAO_0000115 "Joint fluid is a transudate of plasma that is actively secreted by synovial cells."^^xsd:string ;
    obo:IAO_0000118 "joint fluid"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "synovial fluid"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0001114
    obo:IAO_0000115 "The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]."^^xsd:string ;
    obo:IAO_0000118 "liver right lobe"^^xsd:string, "lobus hepaticus dexter"^^xsd:string, "right liver lobe"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "right lobe of liver"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001119
    obo:IAO_0000115 "A lobe of thyroid gland that is in the right side of a thyroid gland."^^xsd:string ;
    obo:IAO_0000118 "lobus dexter (glandula thyroidea)"^^xsd:string, "right thyroid lobe"^^xsd:string, "thyroid gland right lobe"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "right lobe of thyroid gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001120
    obo:IAO_0000115 "A lobe of thyroid gland that is in the left side of a thyroid gland."^^xsd:string ;
    obo:IAO_0000118 "left thyroid lobe"^^xsd:string, "lobus sinister (glandula thyroidea)"^^xsd:string, "thyroid gland left lobe"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "left lobe of thyroid gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001134
    obo:IAO_0000115 "Muscle tissue that consists primarily of skeletal muscle fibers."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "skeletal muscle tissue"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000479 .

obo:UBERON_0001150
    obo:IAO_0000115 "The body of the pancreas is a subsection of the pancreas organ in the human body. It is somewhat prismatic in shape, and has three surfaces: anterior, posterior, and inferior. It is at the same level as the transpyloric plane. [WP,unvetted]."^^xsd:string ;
    obo:IAO_0000118 "pancreas body"^^xsd:string, "pancreatic body"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "body of pancreas"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001153
    obo:IAO_0000115 "A pouch in the digestive tract that connects the ileum with the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve, and is the beginning of the large intestine. It is also separated from the colon by the cecocolic junction."^^xsd:string ;
    obo:IAO_0000118 "caecum"^^xsd:string, "cecum"^^xsd:string, "intestinum crassum caecum"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "caecum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001155
    obo:IAO_0000115 "Last portion of the large intestine before it becomes the rectum."^^xsd:string ;
    obo:IAO_0000118 "large bowel"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "colon"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001156
    obo:IAO_0000115 "Section of colon which is distal to the cecum and proximal to the transversecolon.[FMA,modified]"^^xsd:string ;
    obo:IAO_0000118 "colon ascendens"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "ascending colon"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001157
    obo:IAO_0000115 "The proximal-distal subdivision of colon that runs transversely across the upper part of the abdomen, from the right to the left colic flexure. Continuous with the descending colon[BTO,modified]."^^xsd:string ;
    obo:IAO_0000118 "colon transversum"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "transverse colon"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001158
    obo:IAO_0000115 "The portion of the colon between the left colic flexure and the sigmoid colon at the pelvic brim; the portion of the descending colon lying in the left iliac fossa is sometimes called the iliac colon."^^xsd:string ;
    obo:IAO_0000118 "colon descendens"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "descending colon"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001159
    obo:IAO_0000115 "The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "sigmoid colon"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001161
    obo:IAO_0000115 "The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]."^^xsd:string ;
    obo:IAO_0000118 "corpus gastricum (ventriculare)"^^xsd:string, "gastric body"^^xsd:string, "stomach body"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "body of stomach"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001225
    obo:IAO_0000115 "Outer cortical portion of the kidney, between the renal capsule and the renal medulla."^^xsd:string ;
    obo:IAO_0000118 "cortex renalis"^^xsd:string, "kidney cortex"^^xsd:string, "renal cortex"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "cortex of kidney"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001233
    obo:IAO_0000115 "An adrenal gland that is in the right side of the abdomen"^^xsd:string ;
    obo:IAO_0000118 "glandula suprarenalis dexter"^^xsd:string, "right suprarenal gland"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "right adrenal gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002369 .

obo:UBERON_0001234
    obo:IAO_0000115 "An adrenal gland that is in the left side of the abdomen"^^xsd:string ;
    obo:IAO_0000118 "glandula suprarenalis sinister"^^xsd:string, "left suprarenal gland"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "left adrenal gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002369 .

obo:UBERON_0001255
    obo:IAO_0000115 "distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]."^^xsd:string ;
    obo:IAO_0000118 "vesica urinaria"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "urinary bladder"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001264
    obo:IAO_0000115 "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes[GO]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "pancreas"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001268
    obo:IAO_0000115 "Transudate contained in the peritoneal cavity."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "peritoneal fluid"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0001323
    obo:IAO_0000115 "The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted]."^^xsd:string ;
    obo:IAO_0000118 "medial popliteal nerve"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "tibial nerve"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000477 .

obo:UBERON_0001359
    obo:IAO_0000115 "A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord."^^xsd:string ;
    obo:IAO_0000118 "CSF"^^xsd:string, "cerebral spinal fluid"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "cerebrospinal fluid"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0001388
    obo:IAO_0000115 "The most superficial muscle of the triceps surae group, in the posterior portion of the lower hindleg."^^xsd:string ;
    obo:IAO_0000118 "gastrocnemius muscle"^^xsd:string, "m. gastrocnemius"^^xsd:string, "m.gastrocnemius"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "gastrocnemius"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0001134 .

obo:UBERON_0001496
    obo:IAO_0000115 "The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]"^^xsd:string ;
    obo:IAO_0000118 "ascending thoracic aorta"^^xsd:string, "pars ascendens aortae"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "ascending aorta"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0001557
    obo:IAO_0000115 "The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "upper respiratory tract"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001567
    obo:IAO_0000115 "A fleshy subdivision of one side of the face bounded by an eye, ear and the nose."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "cheek"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001621
    obo:IAO_0000115 "An artery that supplies the myocardium."^^xsd:string ;
    obo:IAO_0000118 "coronary arterial tree"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "coronary artery"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001723
    obo:IAO_0000115 "A muscular organ in the floor of the mouth."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "tongue"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001728
    obo:IAO_0000115 "the section of the pharynx that lies above the soft palate"^^xsd:string ;
    obo:IAO_0000118 "nasal part of pharynx"^^xsd:string, "rhinopharynx"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "nasopharynx"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001729
    obo:IAO_0000115 "the portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis"^^xsd:string ;
    obo:IAO_0000118 "oral part of pharynx"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "oropharynx"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001797
    obo:IAO_0000115 "A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina"^^xsd:string ;
    obo:IAO_0000118 "humor vitreous"^^xsd:string, "humor vitreus"^^xsd:string, "vitreous"^^xsd:string, "whole portion of vitreous humor"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "vitreous humor"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0001830
    obo:IAO_0000115 "One of the smaller, largely mucus-secreting, exocrine glands of the oral cavity, consisting of the labial, buccal, molar, lingual, and palatine glands[MP]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "minor salivary gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001835
    obo:IAO_0000115 "Lip that covers the lower portion of the mouth.[TAO]."^^xsd:string ;
    obo:IAO_0000118 "lower jaw lip"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "lower lip"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001836
    obo:IAO_0000115 "A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions."^^xsd:string ;
    obo:IAO_0000118 "salivary gland secretion"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "saliva"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0001913
    obo:IAO_0000115 "An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation."^^xsd:string ;
    obo:IAO_0000118 "mammary gland milk"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "milk"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0001968
    obo:IAO_0000115 "Organism substance that is composed of sperm cells suspended in seminal fluid."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "semen"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0001970
    obo:IAO_0000115 "vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "bile"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0001981
    obo:IAO_0000115 "A vessel through which blood circulates in the body."^^xsd:string ;
    obo:IAO_0000118 "region of vascular tree organ"^^xsd:string, "vascular tree organ region"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "blood vessel"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001987
    obo:IAO_0000115 "organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell."^^xsd:string ;
    obo:IAO_0000118 "allantoic placenta"^^xsd:string, "eutherian placenta"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "placenta"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0001988
    obo:IAO_0000115 "Portion of semisolid bodily waste discharged through the anus[MW,modified]"^^xsd:string ;
    obo:IAO_0000118 "faeces"^^xsd:string, "fecal material"^^xsd:string, "fecal matter"^^xsd:string, "matières fécales@fr"^^xsd:string, "merde@fr"^^xsd:string, "partie de la merde@fr"^^xsd:string, "piece of shit"^^xsd:string, "porción de mierda@es"^^xsd:string, "portion of excrement"^^xsd:string, "portion of faeces"^^xsd:string, "portion of fecal material"^^xsd:string, "portion of fecal matter"^^xsd:string, "portion of feces"^^xsd:string, "portionem cacas"^^xsd:string, "stool"^^xsd:string, "teil der fäkalien@de"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "feces"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0002032
    obo:IAO_0000115 "Subdivision of breast which consists of skin, connective tissue and smooth muscle bundle and modified sebaceous glands and which surrounds the nipple."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "areola"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002037
    obo:IAO_0000115 "Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]."^^xsd:string ;
    obo:IAO_0000118 "epencephalon-1"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "cerebellum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000481 .

obo:UBERON_0002046
    obo:IAO_0000115 "A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO]."^^xsd:string ;
    obo:IAO_0000118 "thyroid"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "thyroid gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002048
    obo:IAO_0000115 "Respiration organ that develops as an outpocketing of the esophagus."^^xsd:string ;
    obo:IAO_0000118 "pulmo"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "lung"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002078
    obo:IAO_0000115 "A cardiac atrium that is in the left side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve."^^xsd:string ;
    obo:IAO_0000118 "cardiac right atrium"^^xsd:string, "heart right atrium"^^xsd:string, "right atrium"^^xsd:string, "right atrium of heart"^^xsd:string, "right cardiac atrium"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "right cardiac atrium"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002081 .

obo:UBERON_0002081
    obo:IAO_0000115 "Cardiac chamber in which blood enters the heart."^^xsd:string ;
    obo:IAO_0000118 "atria"^^xsd:string, "atrium"^^xsd:string, "atrium of heart"^^xsd:string, "cardiac atria"^^xsd:string, "heart atrium"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "cardiac atrium"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0002084
    obo:IAO_0000115 "A cardiac ventricle that is in the left side of the heart."^^xsd:string ;
    obo:IAO_0000118 "cardiac left ventricle"^^xsd:string, "left cardiac ventricle"^^xsd:string, "left ventricle"^^xsd:string, "left ventricle of heart"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "heart left ventricle"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0002097
    obo:IAO_0000115 "The organ covering the body that consists of the dermis and epidermis."^^xsd:string ;
    obo:IAO_0000118 "entire skin"^^xsd:string, "skin organ"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "skin of body"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002106
    obo:IAO_0000115 "the organ that functions to filter blood and to store red corpuscles and platelets"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "spleen"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002107
    obo:IAO_0000115 "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "liver"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002108
    obo:IAO_0000115 "Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]."^^xsd:string ;
    obo:IAO_0000118 "small bowel"^^xsd:string, "small intestine"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "small intestine"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0002113
    obo:IAO_0000115 "A paired organ of the urinary tract which has the production of urine as its primary function."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "kidney"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002116
    obo:IAO_0000115 "the portion of the small intestine that extends from the jejunum to the colon"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "ileum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0002118
    obo:IAO_0000115 "An ovary that is part of a right side of organism [Automatically generated definition]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "right ovary"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000992 .

obo:UBERON_0002119
    obo:IAO_0000115 "An ovary that is part of a left side of organism [Automatically generated definition]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "left ovary"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000992 .

obo:UBERON_0002167
    obo:IAO_0000115 "Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "right lung"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002048 .

obo:UBERON_0002168
    obo:IAO_0000115 "Lung which consists of the left upper lobe and left lower lobe.[FMA]"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "left lung"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002048 .

obo:UBERON_0002199
    obo:IAO_0000115 "The dermis, epidermis and hypodermis."^^xsd:string ;
    obo:IAO_0000118 "dermis plus epidermis plus hypodermis"^^xsd:string, "integumentum commune"^^xsd:string, "skin and subcutaneous tissue"^^xsd:string, "skin plus hypodermis"^^xsd:string, "the integument"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "integument"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002358
    obo:IAO_0000115 "A serous membrane that lines the peritoneal cavity[VHOG,modified]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "peritoneum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0002367
    obo:IAO_0000115 "The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid."^^xsd:string ;
    obo:IAO_0000118 "male prostate"^^xsd:string, "prostate"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "prostate gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002368
    obo:IAO_0000115 "Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]."^^xsd:string ;
    obo:IAO_0000118 "ductless gland"^^xsd:string, "glandula endocrina"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "endocrine gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002369
    obo:IAO_0000115 "Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO]."^^xsd:string ;
    obo:IAO_0000118 "glandula adrenalis"^^xsd:string, "glandula suprarenalis"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "adrenal gland"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002371
    obo:IAO_0000115 "the soft tissue that fills the cavities of bones"^^xsd:string ;
    obo:IAO_0000118 "medulla ossea"^^xsd:string, "medulla ossium"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "bone marrow"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000479 .

obo:UBERON_0002409
    obo:IAO_0000115 "Transudate contained in the pericardial cavity.[FMA]"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "pericardial fluid"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0006314 .

obo:UBERON_0002415
    obo:IAO_0000115 "An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail"^^xsd:string ;
    obo:IAO_0000118 "caudal subdivision"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "tail"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0002469
    obo:IAO_0000115 "A mucosa that is part of a esophagus [Automatically generated definition]."^^xsd:string ;
    obo:IAO_0000118 "esophageal mucosa"^^xsd:string, "esophageal mucous membrane"^^xsd:string, "esophagus mucosa"^^xsd:string, "esophagus mucous membrane"^^xsd:string, "lamina muscularis mucosae oesophageae"^^xsd:string, "mucosa of esophagus"^^xsd:string, "mucosa of oesophagus"^^xsd:string, "mucous membrane of esophagus"^^xsd:string, "mucous membrane of oesophagus"^^xsd:string, "oesophageal mucosa"^^xsd:string, "oesophagus mucosa"^^xsd:string, "oesophagus mucous membrane"^^xsd:string, "tunica mucosa esophagi"^^xsd:string, "tunica mucosa oesophageae"^^xsd:string, "tunica mucosa oesophagi"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "esophagus mucosa"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0003688
    obo:IAO_0000115 "A fold of peritoneum originating at the stomach and supporting the viscera."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "omentum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0003714
    obo:IAO_0000115 "Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature."^^xsd:string ;
    obo:IAO_0000118 "nerve tissue"^^xsd:string, "nervous tissue"^^xsd:string, "portion of neural tissue"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "neural tissue"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0003889
    obo:IAO_0000115 "Initial section of the oviduct through which the ova pass from the ovary to the uterus"^^xsd:string ;
    obo:IAO_0000118 "mammalian oviduct"^^xsd:string, "uterine tube (sensu Mammalia)"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "fallopian tube"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0004538
    obo:IAO_0000115 "A kidney that is part of a left side of organism [Automatically generated definition]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "left kidney"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002113 .

obo:UBERON_0004539
    obo:IAO_0000115 "A kidney that is part of a right side of organism [Automatically generated definition]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "right kidney"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002113 .

obo:UBERON_0004648
    obo:IAO_0000115 "A muscularis mucosa that is part of a esophagus."^^xsd:string ;
    obo:IAO_0000118 "esophagus muscularis mucosae"^^xsd:string, "lamina muscularis mucosae (oesphagus)"^^xsd:string, "lamina muscularis of esophageal mucous membrane"^^xsd:string, "muscularis mucosae of esophagus"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "esophagus muscularis mucosa"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000479 .

obo:UBERON_0005448
    obo:IAO_0000115 "The greater omentum (also the great omentum, omentum majus, gastrocolic omentum, epiploön, or, especially in animals, caul) is a large fold of peritoneum that hangs down from the stomach, and extends from the stomach to the posterior abdominal wall after associating with the transverse colon."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "greater omentum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0003688 .

obo:UBERON_0006314
    obo:IAO_0000115 "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not."^^xsd:string ;
    obo:IAO_0000118 "body fluid"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "bodily fluid"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0006618
    obo:IAO_0000115 "A small conical pouch projections located on the upper anterior portion of each atrium of the heart."^^xsd:string ;
    obo:IAO_0000118 "atrial appendage"^^xsd:string, "atrial auricle"^^xsd:string, "atrium appendage"^^xsd:string, "auricle of atrium"^^xsd:string, "auricle of heart"^^xsd:string, "auricula (cor)"^^xsd:string, "auricula atrii"^^xsd:string, "auricular appendage"^^xsd:string, "cardiac auricle"^^xsd:string, "heart atrial appendage"^^xsd:string, "heart atrium auriclular region"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "atrium auricular region"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000481 .

obo:UBERON_0006911
    obo:IAO_0000118 "digestive system fluid or secretion"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "digestive system secreted substance"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0007106
    obo:IAO_0000115 "One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "chorionic villus"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0007109
    obo:IAO_0000115 "A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "meconium"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0001988 .

obo:UBERON_0007311
    obo:IAO_0000115 "Matter ejected from the lungs, bronchi, and trachea, through the mouth."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "sputum"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000463 .

obo:UBERON_0007610
    obo:IAO_0000115 "The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and pes. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "tibial artery"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000465 .

obo:UBERON_0007650
    obo:IAO_0000115 "The junction between the esophagus and the stomach epithelium"^^xsd:string ;
    obo:IAO_0000118 "cardioesophageal junction"^^xsd:string, "gastroesophageal junction"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "esophagogastric junction"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0008954
    obo:IAO_0000115 "Anterioinferior portion of left upper lung lobe"^^xsd:string ;
    obo:IAO_0000118 "left pulmonary lingula"^^xsd:string, "lingula of lung"^^xsd:string, "lingula of the lung"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "lingula of left lung"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0009853
    obo:IAO_0000115 "The part of the uterus above the isthmus and below the orifices of the uterine tubes."^^xsd:string ;
    obo:IAO_0000118 "corpus uteri"^^xsd:string, "uterine body"^^xsd:string, "uterine corpus"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "body of uterus"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0010414
    obo:IAO_0000115 "encapsulated adipose tissue associated with the fold of peritoneal tissue that extends from the stomach to the posterior abdominal wall after associating with the transverse colon"^^xsd:string ;
    obo:IAO_0000118 "omental fat depot"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "omental fat pad"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0001013 .

obo:UBERON_0012168
    obo:IAO_0000115 "blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "umbilical cord blood"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000178 .

obo:UBERON_0013755
    obo:IAO_0000115 "A blood that is part of a artery."^^xsd:string ;
    obo:IAO_0000118 "arterial blood"^^xsd:string, "blood in artery"^^xsd:string, "portion of arterial blood"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "arterial blood"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000178 .

obo:UBERON_0013756
    obo:IAO_0000115 "A blood that is part of a vein."^^xsd:string ;
    obo:IAO_0000118 "blood in vein"^^xsd:string, "portion of venous blood"^^xsd:string, "venous blood"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "venous blood"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000178 .

obo:UBERON_0013757
    obo:IAO_0000115 "A blood that is part of a capillary."^^xsd:string ;
    obo:IAO_0000118 "blood in capillary"^^xsd:string, "portion of blood in capillary"^^xsd:string, "portion of capillary blood"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "capillary blood"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000178 .

obo:UBERON_0022276
    obo:IAO_0000115 "The splenic (or left colic) flexure is a sharp bend between the transverse and the descending colon in the left upper quadrant of humans. The left colic flexure is near the spleen, and hence called the splenic flexure. There are two colic flexures in the transverse colon &mdash; the other being the hepatic flexure in the right upper quadrant."^^xsd:string ;
    obo:IAO_0000118 "flexura coli splenica"^^xsd:string, "left colic flexure"^^xsd:string, "splenic flexure"^^xsd:string, "splenic flexure of colon"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "splenic flexure of colon"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0022277
    obo:IAO_0000115 "Hepatic (or the right colic) flexure is the sharp bend between the ascending and the transverse colon. The right colic flexure is adjacent to the liver, and is therefore also known as the hepatic flexure. Thus, the left colic flexure is also known as the splenic flexure (as it is close to the spleen). The hepatic flexure lies in the right upper quadrant of the abdomen in humans."^^xsd:string ;
    obo:IAO_0000118 "flexura coli heaptica"^^xsd:string, "hepatic flexure"^^xsd:string, "hepatic flexure of colon"^^xsd:string, "right colic flexure"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "hepatic flexure of colon"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0035840
    obo:IAO_0000115 "muscularis mucosa from the lowest portion of the esophagus, just proximal to the stomach."^^xsd:string ;
    obo:IAO_0000118 "gastro-esophageal junction muscularis mucosa"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "esophagogastric junction muscularis mucosa"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UBERON_0035944
    obo:IAO_0000115 "A life cycle temporal boundary that marks the end of the life cycle of the organism."^^xsd:string ;
    obo:IAO_0000118 "end of life cycle"^^xsd:string, "moment of death"^^xsd:string, "time of death"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "life-death temporal boundary"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000035 .

obo:UBERON_0036149
    obo:IAO_0000115 "Area of skin in the hypoastric region of the abdomen."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "suprapubic skin"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0002097 .

obo:UBERON_0036214
    obo:IAO_0000115 "An anatomical junction that is between the sigmoid colon and rectum."^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uberon.owl> ;
    a owl:Class ;
    rdfs:label "rectosigmoid junction"^^xsd:string ;
    rdfs:subClassOf obo:UBERON_0000064 .

obo:UO_0000001
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a owl:Class ;
    rdfs:label "length unit"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000002
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a owl:Class ;
    rdfs:label "mass unit"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000003
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a owl:Class ;
    rdfs:label "time unit"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000005
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a owl:Class ;
    rdfs:label "temperature unit"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000010
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000003, owl:NamedIndividual ;
    rdfs:label "second"^^xsd:string .

obo:UO_0000027
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000005, owl:NamedIndividual ;
    rdfs:label "degree Celsius"^^xsd:string .

obo:UO_0000031
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000003, owl:NamedIndividual ;
    rdfs:label "minute"^^xsd:string .

obo:UO_0000032
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000003, owl:NamedIndividual ;
    rdfs:label "hour"^^xsd:string .

obo:UO_0000033
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000003, owl:NamedIndividual ;
    rdfs:label "day"^^xsd:string .

obo:UO_0000034
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000003, owl:NamedIndividual ;
    rdfs:label "week"^^xsd:string .

obo:UO_0000035
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000003, owl:NamedIndividual ;
    rdfs:label "month"^^xsd:string .

obo:UO_0000036
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000003, owl:NamedIndividual ;
    rdfs:label "year"^^xsd:string .

obo:UO_0000051
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a owl:Class ;
    rdfs:label "concentration unit"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000062
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "molar"^^xsd:string .

obo:UO_0000063
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "millimolar"^^xsd:string .

obo:UO_0000064
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "micromolar"^^xsd:string .

obo:UO_0000065
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "nanomolar"^^xsd:string .

obo:UO_0000066
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "picomolar"^^xsd:string .

obo:UO_0000095
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a owl:Class ;
    rdfs:label "volume unit"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000003 .

obo:UO_0000163
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "mass percentage"^^xsd:string .

obo:UO_0000164
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "mass volume percentage"^^xsd:string .

obo:UO_0000165
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "volume percentage"^^xsd:string .

obo:UO_0000175
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "gram per liter"^^xsd:string .

obo:UO_0000176
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "milligram per milliliter"^^xsd:string .

obo:UO_0000195
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000005, owl:NamedIndividual ;
    rdfs:label "degree Fahrenheit"^^xsd:string .

obo:UO_0000196
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "pH"^^xsd:string .

obo:UO_0000207
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "milliliter per liter"^^xsd:string .

obo:UO_0000208
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "gram per deciliter"^^xsd:string .

obo:UO_0000212
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "colony forming unit per volume"^^xsd:string .

obo:UO_0000301
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/uo.owl> ;
    a obo:UO_0000051, owl:NamedIndividual ;
    rdfs:label "microgram per liter"^^xsd:string .

apollo_sv:APOLLO_SV_0000040
    a owl:AnnotationProperty .

<http://purl.obolibrary.org/obo/cl#lacks_part>
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/cl.owl> ;
    obo:IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y"^^xsd:string ;
    oboInOwl:hasOBONamespace "RO"^^xsd:string ;
    a owl:ObjectProperty ;
    rdfs:label "lacks_part"^^xsd:string .

<http://purl.obolibrary.org/obo/obib.owl>
    dc:contributor "Alice Nzinga", "Chris Stoeckert", "Jan-Eric Litton", "Jie Zheng", "Loreana Norlin", "Maria Anderberg", "Martin N. Fransson", "Mathias Brochhausen", "Mikael Eriksson", "Roxana Merino-Martinez", "Sanela Kjellqvist", "William R. Hogan" ;
    dc:description "The Ontology for Biobanking (OBIB) is an ontology for the annotation and modeling of the activities, contents, and administration of a biobank. Biobanks are facilities that store specimens, such as bodily fluids and tissues, typically along with specimen annotation and clinical data. OBIB is based on a subset of the Ontology for Biomedical Investigation (OBI), has the Basic Formal Ontology (BFO) as its upper ontology, and is developed following OBO Foundry principles. The first version of OBIB resulted from the merging of two existing biobank-related ontologies, OMIABIS and biobank ontology." ;
    dc:source "MIABIS_v2_accepted and UPenn Biobank ontology"@en ;
    dc:title "Ontology for BIoBanking (OBIB)"@en ;
    terms:license <http://creativecommons.org/licenses/by/4.0/> ;
    a owl:Ontology ;
    owl:versionIRI <http://purl.obolibrary.org/obo/obib/2021-11-12/obib.owl> ;
    owl:versionInfo "2021-11-12"^^xsd:string, "development version"@en .

dc:contributor
    a owl:AnnotationProperty .

dc:coverage
    a owl:AnnotationProperty .

dc:creator
    a owl:AnnotationProperty .

dc:date
    a owl:AnnotationProperty .

dc:description
    a owl:AnnotationProperty .

dc:format
    a owl:AnnotationProperty .

dc:identifier
    a owl:AnnotationProperty .

dc:language
    a owl:AnnotationProperty .

dc:license
    a owl:AnnotationProperty .

dc:member
    a owl:AnnotationProperty .

dc:publisher
    a owl:AnnotationProperty .

dc:relation
    a owl:AnnotationProperty .

dc:rights
    a owl:AnnotationProperty .

dc:source
    a owl:AnnotationProperty .

dc:subject
    a owl:AnnotationProperty .

dc:title
    a owl:AnnotationProperty .

dc:type
    a owl:AnnotationProperty .

terms:license
    a owl:AnnotationProperty .

<http://vivoweb.org/ontology/core#Laboratory>
    obo:IAO_0000111 "Laboratory"^^xsd:string ;
    obo:IAO_0000115 "An organizational unit (as opposed to the physical facility) that performs research, provides services, or processes materials"^^xsd:string ;
    obo:IAO_0000412 <http://purl.obolibrary.org/obo/ero.owl> ;
    a owl:Class ;
    rdfs:label "Laboratory"^^xsd:string ;
    rdfs:subClassOf obo:OBI_0000245 .

<http://www.ebi.ac.uk/efo/EFO_0003919>
    obo:IAO_0000115 "An aspect of personal behavior or lifestyle, environmental exposure, or inborn or inherited characteristic, which, on the basis of epidemiologic evidence, is known to be associated with a health-related condition considered important to prevent."^^xsd:string, "Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury."^^xsd:string ;
    obo:IAO_0000412 <http://www.ebi.ac.uk/efo/efo.owl> ;
    a owl:Class ;
    rdfs:label "risk factor"^^xsd:string ;
    rdfs:subClassOf obo:BFO_0000016 .

<http://www.ebi.ac.uk/efo/EFO_0003961>
    obo:IAO_0000115 "Therapeutic use of hormones to alleviate the effects of hormone deficiency."^^xsd:string ;
    obo:IAO_0000412 <http://www.ebi.ac.uk/efo/efo.owl> ;
    a owl:Class ;
    rdfs:label "hormone replacement therapy"^^xsd:string ;
    rdfs:subClassOf obo:OGMS_0000090 .

<http://www.ebi.ac.uk/efo/EFO_0004318>
    obo:IAO_0000115 "Inhaling and exhaling the smoke of tobacco or something similar to tobacco."^^xsd:string ;
    obo:IAO_0000412 <http://www.ebi.ac.uk/efo/efo.owl> ;
    a owl:Class ;
    rdfs:label "smoking behavior"^^xsd:string ;
    rdfs:subClassOf obo:GO_0008150, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:unionOf (obo:OBIB_0000044
                obo:OBIB_0000046
                obo:OBIB_0000055
            )
        ]
    ] .

<http://www.ebi.ac.uk/efo/EFO_0004774>
    obo:IAO_0000115 "Mastication of tobacco, correlated with an increased risk of oral cancers."^^xsd:string ;
    obo:IAO_0000412 <http://www.ebi.ac.uk/efo/efo.owl> ;
    a owl:Class ;
    rdfs:label "chewing tobacco behavior"^^xsd:string ;
    rdfs:subClassOf obo:GO_0008150, [
        a owl:Restriction ;
        owl:onProperty obo:OBI_0000293 ;
        owl:someValuesFrom obo:OBIB_0000047
    ] .

<http://www.ebi.ac.uk/efo/EFO_0004950>
    obo:IAO_0000115 "The point in time at which an individual was born."^^xsd:string ;
    obo:IAO_0000412 <http://www.ebi.ac.uk/efo/efo.owl> ;
    a owl:Class ;
    rdfs:label "date of birth"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

<http://www.ebi.ac.uk/efo/EFO_0004953>
    obo:IAO_0000115 "The point at which a clinical diagnosis is made."^^xsd:string ;
    obo:IAO_0000412 <http://www.ebi.ac.uk/efo/efo.owl> ;
    a owl:Class ;
    rdfs:label "date of diagnosis"^^xsd:string ;
    rdfs:subClassOf obo:IAO_0000416 .

oboInOwl:ObsoleteClass
    a owl:Class ;
    rdfs:label "Obsolete Class" ;
    rdfs:subClassOf owl:Thing .

oboInOwl:created_by
    a owl:AnnotationProperty .

oboInOwl:creation_date
    a owl:AnnotationProperty .

oboInOwl:hasOBONamespace
    a owl:AnnotationProperty .

rdf:PlainLiteral
    a rdfs:Datatype .

rdfs:Literal
    a rdfs:Datatype .

rdfs:comment
    a owl:AnnotationProperty .

rdfs:isDefinedBy
    a owl:AnnotationProperty .

rdfs:label
    a owl:AnnotationProperty ;
    rdfs:label "label" .

rdfs:seeAlso
    a owl:AnnotationProperty .

xsd:float
    a rdfs:Datatype .

xsd:integer
    a rdfs:Datatype .

xsd:nonNegativeInteger
    a rdfs:Datatype .

xsd:string
    a rdfs:Datatype .

foaf:homepage
    a owl:AnnotationProperty .

foaf:mbox
    a owl:AnnotationProperty .

<urn:swrl#d>
    a swrl:Variable .

<urn:swrl#e>
    a swrl:Variable .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/083-003> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:BFO_0000015 ;
    owl:annotatedTarget "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/083-003> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000015 ;
    owl:annotatedTarget "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/062-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000016 ;
    owl:annotatedTarget "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/063-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000016 ;
    owl:annotatedTarget "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/063-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000016 ;
    owl:annotatedTarget "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/062-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000016 ;
    owl:annotatedTarget "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/058-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000017 ;
    owl:annotatedTarget "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/060-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000017 ;
    owl:annotatedTarget "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/060-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000017 ;
    owl:annotatedTarget "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/058-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000017 ;
    owl:annotatedTarget "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/037-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000018 ;
    owl:annotatedTarget "A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/037-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000018 ;
    owl:annotatedTarget "(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/055-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000019 ;
    owl:annotatedTarget "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/105-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000019 ;
    owl:annotatedTarget "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/055-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000019 ;
    owl:annotatedTarget "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/105-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000019 ;
    owl:annotatedTarget "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/050-003> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:BFO_0000020 ;
    owl:annotatedTarget "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000005> ;
    a owl:Axiom ;
    rdfs:comment "per discussion with Barry Smith" ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000020 ;
    owl:annotatedTarget "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc."@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/050-003> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000020 ;
    owl:annotatedTarget "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/061-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000023 ;
    owl:annotatedTarget "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/061-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000023 ;
    owl:annotatedTarget "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/027-004> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000024 ;
    owl:annotatedTarget "b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of  c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/027-004> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000024 ;
    owl:annotatedTarget "(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/038-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000026 ;
    owl:annotatedTarget "A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/038-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000026 ;
    owl:annotatedTarget "(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000011> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000027 ;
    owl:annotatedTarget "An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000301> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000027 ;
    owl:annotatedTarget "An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000300> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000119 ;
    owl:annotatedSource obo:BFO_0000027 ;
    owl:annotatedTarget "ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158." .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/025-004> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000027 ;
    owl:annotatedTarget "b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/025-004> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000027 ;
    owl:annotatedTarget "(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/040-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000028 ;
    owl:annotatedTarget "A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/040-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000028 ;
    owl:annotatedTarget "(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/034-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000029 ;
    owl:annotatedTarget "b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/034-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000029 ;
    owl:annotatedTarget "(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/024-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000030 ;
    owl:annotatedTarget "b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/074-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:BFO_0000031 ;
    owl:annotatedTarget "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/074-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000031 ;
    owl:annotatedTarget "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/064-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000034 ;
    owl:annotatedTarget "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/064-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000034 ;
    owl:annotatedTarget "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/084-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:BFO_0000035 ;
    owl:annotatedTarget "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/085-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000035 ;
    owl:annotatedTarget "Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/085-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000035 ;
    owl:annotatedTarget "(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/084-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000035 ;
    owl:annotatedTarget "(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/103-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000038 ;
    owl:annotatedTarget "A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/103-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000038 ;
    owl:annotatedTarget "(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/019-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000040 ;
    owl:annotatedTarget "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/020-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000040 ;
    owl:annotatedTarget "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/021-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000040 ;
    owl:annotatedTarget "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/019-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000040 ;
    owl:annotatedTarget "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/021-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000040 ;
    owl:annotatedTarget "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/020-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000040 ;
    owl:annotatedTarget "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/029-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:BFO_0000140 ;
    owl:annotatedTarget "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000008> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000140 ;
    owl:annotatedTarget "Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions."@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/029-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000140 ;
    owl:annotatedTarget "(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/032-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000142 ;
    owl:annotatedTarget "a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/032-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000142 ;
    owl:annotatedTarget "(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/093-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:BFO_0000144 ;
    owl:annotatedTarget "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/094-005> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000144 ;
    owl:annotatedTarget "b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/094-005> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000144 ;
    owl:annotatedTarget "(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/093-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000144 ;
    owl:annotatedTarget "(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/057-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:BFO_0000145 ;
    owl:annotatedTarget "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/057-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000145 ;
    owl:annotatedTarget "(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/033-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000146 ;
    owl:annotatedTarget "a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/033-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000146 ;
    owl:annotatedTarget "(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000001> ;
    a owl:Axiom ;
    rdfs:comment "requested by Melanie Courtot" ;
    rdfs:seeAlso <https://groups.google.com/d/msg/bfo-owl-devel/s9Uug5QmAws/ZDRnpiIi_TUJ> ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000147 ;
    owl:annotatedTarget "zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona."@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/031-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000147 ;
    owl:annotatedTarget "a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/031-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000147 ;
    owl:annotatedTarget "(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/102-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000148 ;
    owl:annotatedTarget "A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/102-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000148 ;
    owl:annotatedTarget "(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/138-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000182 ;
    owl:annotatedTarget "A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])"@en .

[]
    a owl:AllDifferent ;
    owl:distinctMembers (obo:IAO_0000120
        obo:IAO_0000121
        obo:IAO_0000122
        obo:IAO_0000123
        obo:IAO_0000124
        obo:IAO_0000125
        obo:IAO_0000423
        obo:IAO_0000428
    ) .

[]
    a owl:AllDifferent ;
    owl:distinctMembers (obo:IAO_0000226
        obo:IAO_0000227
        obo:IAO_0000228
        obo:IAO_0000229
    ) .

[]
    a swrl:Imp ;
    swrl:body ([
            a swrl:IndividualPropertyAtom ;
            swrl:argument1 <urn:swrl#e> ;
            swrl:argument2 <urn:swrl#d> ;
            swrl:propertyPredicate obo:RO_0000053
        ]
        [
            a swrl:ClassAtom ;
            swrl:argument1 <urn:swrl#d> ;
            swrl:classPredicate obo:BFO_0000016
        ]
    ) ;
    swrl:head ([
            a swrl:IndividualPropertyAtom ;
            swrl:argument1 <urn:swrl#e> ;
            swrl:argument2 <urn:swrl#d> ;
            swrl:propertyPredicate obo:RO_0000091
        ]
    ) .

[]
    a swrl:Imp ;
    swrl:body ([
            a swrl:IndividualPropertyAtom ;
            swrl:argument1 <urn:swrl#e> ;
            swrl:argument2 <urn:swrl#d> ;
            swrl:propertyPredicate obo:RO_0000053
        ]
        [
            a swrl:ClassAtom ;
            swrl:argument1 <urn:swrl#d> ;
            swrl:classPredicate obo:BFO_0000019
        ]
    ) ;
    swrl:head ([
            a swrl:IndividualPropertyAtom ;
            swrl:argument1 <urn:swrl#e> ;
            swrl:argument2 <urn:swrl#d> ;
            swrl:propertyPredicate obo:RO_0000086
        ]
    ) .

[]
    a swrl:Imp ;
    swrl:body ([
            a swrl:IndividualPropertyAtom ;
            swrl:argument1 <urn:swrl#e> ;
            swrl:argument2 <urn:swrl#d> ;
            swrl:propertyPredicate obo:RO_0000053
        ]
        [
            a swrl:ClassAtom ;
            swrl:argument1 <urn:swrl#d> ;
            swrl:classPredicate obo:BFO_0000023
        ]
    ) ;
    swrl:head ([
            a swrl:IndividualPropertyAtom ;
            swrl:argument1 <urn:swrl#e> ;
            swrl:argument2 <urn:swrl#d> ;
            swrl:propertyPredicate obo:RO_0000087
        ]
    ) .

[]
    a swrl:Imp ;
    swrl:body ([
            a swrl:IndividualPropertyAtom ;
            swrl:argument1 <urn:swrl#e> ;
            swrl:argument2 <urn:swrl#d> ;
            swrl:propertyPredicate obo:RO_0000053
        ]
        [
            a swrl:ClassAtom ;
            swrl:argument1 <urn:swrl#d> ;
            swrl:classPredicate obo:BFO_0000034
        ]
    ) ;
    swrl:head ([
            a swrl:IndividualPropertyAtom ;
            swrl:argument1 <urn:swrl#e> ;
            swrl:argument2 <urn:swrl#d> ;
            swrl:propertyPredicate obo:RO_0000085
        ]
    ) .

[]
    obo:IAO_0000116 "This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation." ;
    a owl:Axiom ;
    owl:annotatedProperty rdfs:domain ;
    owl:annotatedSource obo:RO_0001025 ;
    owl:annotatedTarget obo:BFO_0000004 .

[]
    obo:IAO_0000116 "This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation." ;
    a owl:Axiom ;
    owl:annotatedProperty rdfs:range ;
    owl:annotatedSource obo:RO_0001025 ;
    owl:annotatedTarget obo:BFO_0000004 .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000004> ;
    a owl:Axiom ;
    rdfs:comment "per discussion with Barry Smith" ;
    rdfs:seeAlso <http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf> ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000001 ;
    owl:annotatedTarget "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/001-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000001 ;
    owl:annotatedTarget "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000007> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/008-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/126-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/009-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/011-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/009-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/126-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/008-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/011-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000002 ;
    owl:annotatedTarget "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000006> ;
    a owl:Axiom ;
    rdfs:comment "per discussion with Barry Smith" ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000003 ;
    owl:annotatedTarget "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process."@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000012> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000003 ;
    owl:annotatedTarget "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/077-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000003 ;
    owl:annotatedTarget "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/108-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000003 ;
    owl:annotatedTarget "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/079-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000003 ;
    owl:annotatedTarget "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/108-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000003 ;
    owl:annotatedTarget "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/079-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000003 ;
    owl:annotatedTarget "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/017-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:BFO_0000004 ;
    owl:annotatedTarget "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/134-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000004 ;
    owl:annotatedTarget "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/018-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000004 ;
    owl:annotatedTarget "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/134-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000004 ;
    owl:annotatedTarget "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/018-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000004 ;
    owl:annotatedTarget "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/017-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000004 ;
    owl:annotatedTarget "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000002> ;
    a owl:Axiom ;
    rdfs:comment "per discussion with Barry Smith" ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000006 ;
    owl:annotatedTarget "Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional."@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/035-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000006 ;
    owl:annotatedTarget "A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/036-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000006 ;
    owl:annotatedTarget "All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/036-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000006 ;
    owl:annotatedTarget "(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/035-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000006 ;
    owl:annotatedTarget "(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/0000003> ;
    a owl:Axiom ;
    rdfs:comment "per discussion with Barry Smith" ;
    owl:annotatedProperty obo:IAO_0000116 ;
    owl:annotatedSource obo:BFO_0000008 ;
    owl:annotatedTarget "Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/100-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000008 ;
    owl:annotatedTarget "A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/101-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000008 ;
    owl:annotatedTarget "All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/119-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000008 ;
    owl:annotatedTarget "Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/119-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000008 ;
    owl:annotatedTarget "(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/101-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000008 ;
    owl:annotatedTarget "(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/100-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000008 ;
    owl:annotatedTarget "(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/039-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000009 ;
    owl:annotatedTarget "A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/039-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000009 ;
    owl:annotatedTarget "(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/096-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/095-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/098-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/095-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000600 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/096-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/099-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/098-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/107-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000601 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])"@en .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/107-002> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] " .

[]
    obo:IAO_0010000 <http://purl.obolibrary.org/obo/bfo/axiom/099-001> ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000602 ;
    owl:annotatedSource obo:BFO_0000011 ;
    owl:annotatedTarget "(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] " .

