Genetic variations can span any level of granularity from a full genome or genotype to an individual gene or sequence alteration. These variations can be represented at the physical level (DNA/RNA macromolecules or their parts, as in the ChEBI ontology and Molecular Sequence Ontology) or at the abstract level (generically dependent continuant sequence features that are carried by these macromolecules, as in the Sequence Ontology and Genotype Ontology). The causal relations in this hierarchy can be used in linking either physical or abstract genetic variations to phenotypes or diseases they cause or contribute to. Environmental exposures include those imposed by natural environments, experimentally applied conditions, or clinical interventions.

has super-properties: contributes to severity of condition^op

anabranch of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002378

has super-properties: distributary of^op

attached to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002371

has characteristics : symmetric

has super-properties: connected to^op; attached to part of^op
has sub-properties: has muscle insertion^op, has muscle origin^op

attached to part of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002177

has super-properties: mereotopologically related to^op; biomechanically related to^op
has sub-properties: attached to^op
has domain: u b e r o n 0000061^c
has range: u b e r o n 0000061^c

axon synapses in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002102

has super-properties: has presynaptic terminal in^op
has domain: c l 0000540^c

before^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002083

t1 before t2 iff:= t1 before_or_simulataneous_with t2 and not (t1 simultaeous_with t2)

has characteristics : transitive

has super-properties: before or simultaneous with^op

before or simultaneous with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002081

Primitive instance level timing relation between events

has super-properties: temporally related to^op
has sub-properties: before^op, simultaneous with^op

biomechanically related to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002567

has super-properties: functionally related to^op
has sub-properties: attached to part of^op, has muscle antagonist^op, has muscle insertion^op, has muscle origin^op
has domain: u b e r o n 0000061^c
has range: u b e r o n 0000061^c

biotically interacts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002437

has characteristics : symmetric

has super-properties: ecologically related to^op; interacts with^op
has sub-properties: acquires nutrients from^op, eats^op, is eaten by^op, participates in a abiotic-biotic interaction with^op, participates in a biotic-biotic interaction with^op, provides nutrients for^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

bounding layer of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002007

A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane.

has super-properties: part of^op
has domain: b f o 0000040^c and (has characteristic^op some p a t o 0002124^c)
has range: b f o 0000040^c

bounds sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002522

has characteristics : transitive

has super-properties: sequentially related to^op
has sub-properties: has subsequence^op
is inverse of: is bound by sequence of^op

branching part of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002380

has super-properties: part of^op; in branching relationship with^op
has range: has characteristic^op some p a t o 0000402^c
is inverse of: has branching part^op

capable of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002215

has super-properties: capable of part of^op
has sub-properties: enables^op
has domain: b f o 0000004^c
has range: b f o 0000015^c

capable of inhibiting or preventing pathological process^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002599

has super-properties: capable of negatively regulating^op
has sub-properties: is substance that treats^op

capable of negatively regulating^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002597

has super-properties: capable of regulating^op
has sub-properties: capable of inhibiting or preventing pathological process^op, is small molecule inhibitor of^op

capable of part of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002216

has super-properties: functionally related to^op; causal agent in process^op
has sub-properties: capable of^op, contributes to^op

capable of positively regulating^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002598

has super-properties: capable of regulating^op
has sub-properties: capable of upregulating or causing pathological process^op, is small molecule activator of^op

capable of regulating^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002596

has super-properties: causal agent in process^op
has sub-properties: capable of negatively regulating^op, capable of positively regulating^op, is small molecule regulator of^op

capable of upregulating or causing pathological process^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002600

has super-properties: capable of positively regulating^op

causal agent in process^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002500

has super-properties: causal relation between material entity and a process^op
has sub-properties: acts upstream of or within^op, capable of part of^op, capable of regulating^op, involved in or involved in regulation of^op
is inverse of: process has causal agent^op

causal relation between entities^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002506

has super-properties: causally related to^op
has sub-properties: causally influenced by^op, causally influences^op, determined by part of^op
has domain: b f o 0000002^c
has range: b f o 0000002^c

causal relation between material entity and a process^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002595

has super-properties: causally related to^op
has sub-properties: causal agent in process^op, has part structure that is capable of^op
has domain: b f o 0000040^c
has range: b f o 0000015^c

causal relation between processes^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002501

has super-properties: causally related to^op
has sub-properties: causally downstream of or within^op, causally upstream of or within^op
has domain: b f o 0000003^c
has range: b f o 0000003^c

causal relationship with disease as subject^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004023

has super-properties: causally related to^op; disease relationship^op
has sub-properties: disease causes disruption of^op, disease causes dysfunction of^op, disease has basis in^op
has domain: o g m s 0000031^c

causally downstream of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002404

has super-properties: preceded by^op; causally downstream of or within^op
has sub-properties: immediately causally downstream of^op
is inverse of: causally upstream of^op

causally downstream of or within^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002427

has characteristics : transitive

has super-properties: causal relation between processes^op
has sub-properties: causally downstream of^op, regulated by^op
is inverse of: causally upstream of or within^op

causally influenced by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002559

has super-properties: causal relation between entities^op
has sub-properties: determined by^op
is inverse of: causally influences^op

causally influences^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002566

has super-properties: causal relation between entities^op
has sub-properties: determines^op, regulates activity of^op, regulates quantity of^op
has domain: b f o 0000002^c
has range: b f o 0000002^c
is inverse of: causally influenced by^op

causally related to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002410

has sub-properties: causal relation between entities^op, causal relation between material entity and a process^op, causal relation between processes^op, causal relationship with disease as subject^op, causes or contributes to condition^op, condition ameliorated by^op, condition exacerbated by^op, condition has genetic basis in^op, is basis for realizable^op, is treated by substance^op, process has causal agent^op, realizable has basis in^op, realized in response to^op, realized in response to stimulus^op, regulates characteristic^op, related via exposure to^op

causally upstream of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002411

has characteristics : transitive

has super-properties: precedes^op; causally upstream of or within^op
has sub-properties: causally upstream of, negative effect^op, causally upstream of, positive effect^op, immediately causally upstream of^op, indirectly causally upstream of^op, regulates^op
is inverse of: causally downstream of^op

causally upstream of or within^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002418

has characteristics : transitive

has super-properties: causal relation between processes^op
has sub-properties: causally upstream of^op, causally upstream of or within, negative effect^op, causally upstream of or within, positive effect^op, occurrent part of^op, regulates in another organism^op
is inverse of: causally downstream of or within^op

causally upstream of or within, negative effect^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004046

has super-properties: causally upstream of or within^op
has sub-properties: causally upstream of, negative effect^op

causally upstream of or within, positive effect^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004047

has super-properties: causally upstream of or within^op
has sub-properties: causally upstream of, positive effect^op, transitively provides input for^op

causally upstream of, negative effect^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002305

has super-properties: causally upstream of^op; causally upstream of or within, negative effect^op
has sub-properties: negatively regulates^op, removes input for^op

causally upstream of, positive effect^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002304

holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y

has super-properties: causally upstream of^op; causally upstream of or within, positive effect^op
has sub-properties: constitutively upstream of^op, positively regulates^op

causes condition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003303

has super-properties: causes or contributes to condition^op
has sub-properties: is causal germline mutation in^op, is causal somatic mutation in^op

causes or contributes to condition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003302

has super-properties: causally related to^op
has sub-properties: causes condition^op, contributes to condition^op, has allergic trigger^op, has autoimmune trigger^op, is allergic trigger for^op, is autoimmune trigger for^op

characteristic of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000052

Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.

has characteristics : functional

has super-properties: characteristic of part of^op
has sub-properties: disposition of^op, function of^op, quality of^op, role of^op
is inverse of: has characteristic^op

characteristic of part of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002314

has super-properties: depends on^op
has sub-properties: characteristic of^op

child nucleus of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002476

has super-properties: developmentally preceded by^op
has sub-properties: child nucleus of in hermaphrodite^op, child nucleus of in male^op
has domain: g o 0005634^c
has range: g o 0005634^c

child nucleus of in hermaphrodite^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002477

has super-properties: child nucleus of^op

child nucleus of in male^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002478

has super-properties: child nucleus of^op

co-roosts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002801

has characteristics : symmetric

has super-properties: ecologically co-occurs with^op

coincident with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002008

Example: if we define region of chromosome as any subdivision of a chromosome along its long axis, then we can define a region of chromosome that contains only gene x as 'chromosome region' that coincident_with some 'gene x', where the term gene X corresponds to a genomic sequence.

has super-properties: mereotopologically related to^op
has domain: b f o 0000002^c and (has characteristic^op some p a t o 0001199^c)
has range: b f o 0000002^c and (has characteristic^op some p a t o 0001199^c)

colocalizes with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002325

has super-properties: mereotopologically related to^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

commensually interacts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002441

has super-properties: symbiotically interacts with^op

composed primarily of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002473

has super-properties: has part^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

condition ameliorated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003310

has super-properties: causally related to^op

condition exacerbated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003311

has super-properties: causally related to^op

condition has genetic basis in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004000

has super-properties: causally related to^op
has sub-properties: has major susceptibility factor^op, has material basis in gain of function germline mutation in^op, has material basis in germline mutation in^op, has material basis in loss of function germline mutation in^op, has material basis in somatic mutation in^op, has partial material basis in germline mutation in^op
has domain: b f o 0000017^c
has range: b f o 0000015^c or b f o 0000019^c or b f o 0000040^c
is inverse of: is genetic basis for condition^op

conduit for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002570

has super-properties: overlaps^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

confers advantage in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002322

has super-properties: ecologically related to^op
has range: e n v o 01000254^c

confers susceptibility to condition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0019501

has super-properties: contributes to condition^op

connected to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002170

has super-properties: mereotopologically related to^op
has sub-properties: attached to^op, connecting branch of^op, distributary of^op, drains^op, electrically_synapsed_to^op, receives input from^op, sends output to^op, supplies^op, tributary of^op
has domain: part of^op some r o 0002577^c
has range: part of^op some r o 0002577^c

connecting branch of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002252

has super-properties: connected to^op; in branching relationship with^op
is inverse of: has connecting branch^op

connects^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002176

has super-properties: mereotopologically related to^op
has domain: b f o 0000004^c
has range: part of^op some r o 0002577^c

constitutively upstream of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012009

has super-properties: causally upstream of, positive effect^op

continuous with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002150

has characteristics : symmetric

has super-properties: mereotopologically related to^op
has domain: b f o 0000004^c
has range: b f o 0000004^c

contributes to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002326

has super-properties: capable of part of^op; part of structure that is capable of^op

contributes to condition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003304

has super-properties: causes or contributes to condition^op
has sub-properties: confers susceptibility to condition^op, contributes to frequency of condition^op, contributes to severity of condition^op, is causal germline mutation partially giving rise to^op

contributes to frequency of condition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003306

has super-properties: contributes to condition^op

contributes to morphology of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002433

has super-properties: overlaps^op

contributes to severity of condition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003305

has super-properties: contributes to condition^op
has sub-properties: ameliorates condition^op, exacerbates condition^op

creates habitat for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008505

has super-properties: ecologically related to^op
has domain: o b i 0100026^c
has range: o b i 0100026^c

decreases by repression quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011007

has super-properties: indirectly negatively regulates quantity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

dendrite synapsed in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002121

has super-properties: has postsynaptic terminal in^op
has domain: c l 0000540^c

depends on^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002502

has sub-properties: characteristic of part of^op, towards^op

destabilizes quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011014

has super-properties: directly negatively regulates quantity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

determined by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002507

has super-properties: part of^op; determined by part of^op; causally influenced by^op
has domain: r o 0002577^c
has range: b f o 0000040^c
is inverse of: determines^op

determined by part of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002509

has super-properties: overlaps^op; causal relation between entities^op
has sub-properties: determined by^op
has domain: r o 0002577^c
has range: b f o 0000040^c

determines^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002508

has super-properties: causally influences^op
is inverse of: determined by^op

developmentally contributes to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002255

has super-properties: developmentally succeeded by^op; has potential to developmentally contribute to^op
is inverse of: has developmental contribution from^op

developmentally induced by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002256

has super-properties: developmentally preceded by^op
has domain: u b e r o n 0000465^c
has range: u b e r o n 0000465^c
is inverse of: developmentally induces^op

developmentally induces^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002257

has super-properties: developmentally succeeded by^op; has potential to developmentally induce^op
is inverse of: developmentally induced by^op

developmentally preceded by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002258

This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from

has super-properties: developmentally related to^op
has sub-properties: child nucleus of^op, developmentally induced by^op, developmentally replaces^op, develops from^op, develops in^op, has developmental contribution from^op
has domain: b f o 0000002^c
has range: b f o 0000002^c
is inverse of: developmentally succeeded by^op

developmentally related to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002324

has sub-properties: developmentally preceded by^op, has developmental potential involving^op, results in developmental progression of^op

developmentally replaces^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002285

has super-properties: developmentally preceded by^op

developmentally succeeded by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002286

has super-properties: has developmental potential involving^op
has sub-properties: developmentally contributes to^op, developmentally induces^op, develops into^op, part of developmental precursor of^op
is inverse of: developmentally preceded by^op

develops from^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002202

This is the transitive form of the develops from relation

has characteristics : transitive

has super-properties: has developmental contribution from^op; developmentally preceded by^op
has sub-properties: develops from part of^op, directly develops from^op, transformation of^op
has domain: b f o 0000004^c
has range: b f o 0000004^c
is inverse of: develops into^op

develops from part of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002225

has super-properties: develops from^op

develops in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002226

has super-properties: developmentally preceded by^op
has domain: u b e r o n 0001062^c

develops into^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002203

has characteristics : transitive

has super-properties: developmentally succeeded by^op; has potential to develop into^op; has potential to directly develop into^op
has sub-properties: directly develops into^op
is inverse of: develops from^op

directly develops from^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002207

TODO - add child relations from DOS

has super-properties: develops from^op
has sub-properties: immediate transformation of^op
has domain: c l 0000000^c or u b e r o n 0010000^c
has range: c l 0000000^c or u b e r o n 0010000^c
is inverse of: directly develops into^op

directly develops into^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002210

has super-properties: develops into^op
is inverse of: directly develops from^op

directly negatively regulated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002023

has super-properties: directly regulated by^op
is inverse of: directly negatively regulates^op

directly negatively regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002630

has super-properties: negatively regulates^op; directly regulates^op
is inverse of: directly negatively regulated by^op

directly negatively regulates activity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002449

has super-properties: directly regulates activity of^op
has sub-properties: is antagonist of^op, is inverse agonist of^op, represses expression of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

directly negatively regulates quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011010

has super-properties: directly regulates quantity of^op
has sub-properties: destabilizes quantity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

directly positively regulated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002024

has super-properties: directly regulated by^op
is inverse of: directly positively regulates^op

directly positively regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002629

has super-properties: positively regulates^op; directly regulates^op
is inverse of: directly positively regulated by^op

directly positively regulates activity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002450

has super-properties: directly regulates activity of^op
has sub-properties: increases expression of^op, is agonist of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

directly positively regulates quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011009

has super-properties: directly regulates quantity of^op
has sub-properties: stabilizes quantity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

directly regulated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002022

Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2.

has super-properties: regulated by^op
has sub-properties: directly negatively regulated by^op, directly positively regulated by^op
is inverse of: directly regulates^op

directly regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002578

has super-properties: regulates^op; immediately causally upstream of^op
has sub-properties: directly negatively regulates^op, directly positively regulates^op
is inverse of: directly regulated by^op

directly regulates activity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002448

has super-properties: molecularly interacts with^op; regulates activity of^op
has sub-properties: directly negatively regulates activity of^op, directly positively regulates activity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

directly regulates quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011021

has super-properties: regulates quantity of^op
has sub-properties: directly negatively regulates quantity of^op, directly positively regulates quantity of^op

directly supplies and drains^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0020103

has super-properties: supplies^op; drains^op
has domain: u b e r o n 0001982^c
has range: u b e r o n 0000061^c

disease arises from alteration in structure^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004030

has super-properties: disease has basis in^op
has range: u b e r o n 0000061^c

disease causes disruption of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004024

has super-properties: causal relationship with disease as subject^op
has domain: o g m s 0000031^c
has range: b f o 0000015^c

disease causes dysfunction of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004025

has super-properties: causal relationship with disease as subject^op
has domain: o g m s 0000031^c
has range: u b e r o n 0000465^c

disease has basis in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004019

has super-properties: realizable has basis in^op; causal relationship with disease as subject^op
has sub-properties: disease arises from alteration in structure^op, disease has basis in disruption of^op, disease has basis in dysfunction of^op, disease has basis in feature^op, disease has infectious agent^op
has domain: o g m s 0000031^c

disease has basis in disruption of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004021

has super-properties: disease has basis in^op
has range: b f o 0000015^c

disease has basis in dysfunction of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004020

has super-properties: disease has basis in^op
has range: u b e r o n 0000465^c

disease has basis in feature^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004022

has super-properties: has phenotype^op; disease has basis in^op
has domain: o g m s 0000031^c
has range: o g m s 0000031^c or u p h e n o 0001001^c

disease has feature^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004029

has super-properties: disease relationship^op
has domain: o g m s 0000031^c
has range: o g m s 0000031^c or u p h e n o 0001001^c

disease has infectious agent^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0014001

has super-properties: disease has basis in^op

disease has inflammation site^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004027

has super-properties: disease has location^op
has domain: o g m s 0000031^c
has range: b f o 0000004^c; u b e r o n 0000465^c or u b e r o n 0000466^c

disease has location^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004026

has super-properties: disease relationship^op
has sub-properties: disease has inflammation site^op
has domain: o g m s 0000031^c
has range: b f o 0000004^c; u b e r o n 0000465^c or u b e r o n 0000466^c

disease relationship^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0040035

has sub-properties: causal relationship with disease as subject^op, disease has feature^op, disease has location^op

disposition of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000092

This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

has super-properties: characteristic of^op
is inverse of: has disposition^op

distributary of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002377

This is both a mereotopological relationship and a relationship defined in connection to processes. It concerns both the connecting structure, and how this structure is disposed to causally affect flow processes

has super-properties: connected to^op; in branching relationship with^op
has sub-properties: anabranch of^op, proper distributary of^op

does not overlap sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002527

has characteristics : symmetric

has super-properties: sequentially related to^op
has sub-properties: is downstream of sequence of^op, is upstream of sequence of^op, sequentially adjacent to^op

drains^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002179

has super-properties: connected to^op
has sub-properties: directly supplies and drains^op, vessel drains blood from^op

during which ends^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002084

Previously had ID http://purl.obolibrary.org/obo/RO_0002122 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

has super-properties: temporally related to^op
is inverse of: ends during^op

during which starts^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002088

Previously had ID http://purl.obolibrary.org/obo/RO_0002123 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

has super-properties: temporally related to^op
has sub-properties: encompasses^op
is inverse of: starts during^op

eats^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002470

has super-properties: biotically interacts with^op

ecologically co-occurs with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008506

has characteristics : symmetric

has super-properties: ecologically related to^op
has sub-properties: co-roosts with^op
has domain: o b i 0100026^c
has range: o b i 0100026^c

ecologically related to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002321

has sub-properties: biotically interacts with^op, confers advantage in^op, creates habitat for^op, ecologically co-occurs with^op, has habitat^op, transmitted by^op

ectoparasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002632

has super-properties: parasite of^op
is inverse of: has ectoparasite^op

electrically_synapsed_to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002003

has super-properties: connected to^op

enabled by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002333

has super-properties: has participant^op; functionally related to^op
is inverse of: enables^op

enables^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002327

has super-properties: capable of^op
is inverse of: enabled by^op

enables subfunction^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004031

has super-properties: functionally related to^op

encompasses^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002085

Previously had ID http://purl.obolibrary.org/obo/RO_0002124 in test files in sandpit - but this seems to have been dropped from ro-edit.owl at some point. No re-use under this ID AFAIK, but leaving note here in case we run in to clashes down the line. Official ID now chosen from DOS ID range.

has characteristics : transitive

has super-properties: during which starts^op
is inverse of: happens during^op

endoparasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002634

has super-properties: parasite of^op
has sub-properties: intercellular endoparasite of^op, intracellular endoparasite of^op
is inverse of: has endoparasite^op

ends^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002229

has super-properties: part of^op; temporally related to^op
is inverse of: ends with^op

ends after^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002086

X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)

has characteristics : transitive

has super-properties: temporally related to^op
has sub-properties: preceded by^op

ends during^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002093

X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y).

has super-properties: temporally related to^op
has sub-properties: happens during^op
is inverse of: during which ends^op

ends with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002230

has characteristics : transitive

has super-properties: has part^op; temporally related to^op
is inverse of: ends^op

epiphyte of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008501

has super-properties: symbiotically interacts with^op
is inverse of: has epiphyte^op

exacerbates condition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003309

has super-properties: contributes to severity of condition^op

exports^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002345

has super-properties: transports^op

facultative parasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002228

has super-properties: parasite of^op

fasciculates with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002101

has super-properties: overlaps^op
has domain: c l 0000540^c
has range: u b e r o n 0000122^c
is inverse of: has fasciculating neuron projection^op

formed as result of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002354

has super-properties: output of^op
is inverse of: results in formation of anatomical entity^op

function of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000079

has super-properties: characteristic of^op
has domain: b f o 0000034^c
is inverse of: has function^op

functionally related to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002328

has sub-properties: biomechanically related to^op, capable of part of^op, enabled by^op, enables subfunction^op, has part structure that is capable of^op, input of^op, involved in or involved in regulation of^op, is active in^op, output of^op, part of structure that is capable of^op, regulates levels of^op

genetically interacts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002435

has characteristics : symmetric

has super-properties: interacts with^op

happens during^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002092

X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))

has characteristics : transitive

has super-properties: starts during^op; ends during^op
is inverse of: encompasses^op

has 2D boundary^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002002

has super-properties: mereotopologically related to^op
has domain: b f o 0000040^c
has range: b f o 0000141^c
is inverse of: 2D boundary of^op

has active ingredient^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002248

has super-properties: has part^op
has domain: b f o 0000040^c
has range: b f o 0000040^c
is inverse of: active ingredient in^op

has allergic trigger^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0001022

has super-properties: causes or contributes to condition^op
has range: b f o 0000040^c
is inverse of: is allergic trigger for^op

has application role^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002261

has super-properties: has role^op

has autoimmune trigger^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0001023

has super-properties: causes or contributes to condition^op
has range: b f o 0000040^c
is inverse of: is autoimmune trigger for^op

has biological role^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002260

has super-properties: has role^op

has branching part^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002569

has characteristics : transitive

has super-properties: has part^op; in branching relationship with^op
is inverse of: branching part of^op

has characteristic^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000053

has characteristics : inverse functional

has sub-properties: has disposition^op, has function^op, has quality^op, has role^op
has range: b f o 0000020^c
is inverse of: characteristic of^op

has chemical role^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002262

has super-properties: has role^op

has component^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002180

has super-properties: has part^op
has sub-properties: has component process^op

has component activity^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002017

A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B.

has super-properties: has component process^op
has sub-properties: has effector activity^op, has necessary component activity^op, has regulatory component activity^op

has component participant^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002238

has super-properties: has participant^op

has component process^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002018

has super-properties: has component^op
has sub-properties: has component activity^op
has domain: b f o 0000015^c
has range: b f o 0000015^c

has connecting branch^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002253

has super-properties: in branching relationship with^op
is inverse of: connecting branch of^op

has dendrite location^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002360

has super-properties: overlaps^op
has sub-properties: has sensory dendrite in^op

has denominator^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0020203

has super-properties: has part^op
has domain: p a t o 0001470^c
has range: p a t o 0000001^c

has developmental contribution from^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002254

has super-properties: developmentally preceded by^op
has sub-properties: develops from^op
has domain: u b e r o n 0001062^c
has range: u b e r o n 0001062^c
is inverse of: developmentally contributes to^op

has developmental potential involving^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002384

has super-properties: developmentally related to^op
has sub-properties: developmentally succeeded by^op, has potential to develop into^op, has potential to developmentally contribute to^op, has potential to developmentally induce^op
has domain: u b e r o n 0001062^c
has range: u b e r o n 0001062^c

has direct input^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002400

has super-properties: has input^op

has disease^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0016002

has super-properties: has phenotype or disease^op

has disposition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000091

has super-properties: has characteristic^op
has domain: b f o 0000004^c
has range: b f o 0000016^c
is inverse of: disposition of^op

has ectoparasite^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002633

has super-properties: parasitized by^op
is inverse of: ectoparasite of^op

has effector activity^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002025

This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations.

has characteristics : functional

has super-properties: has component activity^op

has eggs laid in by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002625

has super-properties: parasitized by^op; visited by^op
is inverse of: lays eggs in^op

has eggs laid on by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008508

has super-properties: visited by^op
is inverse of: lays eggs on^op

has end location^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002232

has super-properties: has part that occurs in^op
has domain: b f o 0000015^c
has range: b f o 0000004^c

has end sequence^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002518

has characteristics : transitive

has super-properties: has subsequence^op
is inverse of: is end sequence of^op

has endoparasite^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002635

has super-properties: parasitized by^op
has sub-properties: has intercellular endoparasite^op, has intracellular endoparasite^op
is inverse of: endoparasite of^op

has epiphyte^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008502

has super-properties: symbiotically interacts with^op
is inverse of: epiphyte of^op

has exposure medium^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0016004

has super-properties: related via exposure to^op

has exposure receptor^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002240

has super-properties: related via exposure to^op

has exposure route^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002242

has super-properties: related via exposure to^op

has exposure stimulus^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002309

has super-properties: related via exposure to^op
has sub-properties: has exposure stressor^op

has exposure stressor^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002241

has super-properties: has exposure stimulus^op

has exposure transport path^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002243

has super-properties: related via exposure to^op

has fasciculating neuron projection^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002132

has super-properties: overlaps^op
has domain: u b e r o n 0000122^c
has range: c l 0000540^c or (part of^op some c l 0000540^c)
is inverse of: fasciculates with^op

has flowers visited by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002623

has super-properties: visited by^op
is inverse of: visits flowers of^op

has function^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000085

has super-properties: has characteristic^op
has domain: b f o 0000004^c
has range: b f o 0000034^c
is inverse of: function of^op

has habitat^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002303

A population of xs will possess adaptations (either evolved naturally or via artifical selection) which permit it to exist and grow in y.

has super-properties: ecologically related to^op
has sub-properties: has roost^op
has domain: o b i 0100026^c
has range: e n v o 01000254^c

has high plasma membrane amount^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0015015

has super-properties: has plasma membrane part^op
has domain: c l 0000000^c

has host^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002454

has super-properties: symbiotically interacts with^op
has sub-properties: has reservoir host^op, hyperparasite of^op, parasite of^op, pathogen of^op

has input^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002233

has super-properties: has participant^op
has sub-properties: has direct input^op, has ligand^op, has primary input^op, results in breakdown of^op, results in remodeling of^op
has domain: b f o 0000015^c
is inverse of: input of^op

has intercellular endoparasite^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002639

has super-properties: has endoparasite^op
is inverse of: intercellular endoparasite of^op

has intermediate^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002505

has super-properties: has participant^op

has intracellular endoparasite^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002641

has super-properties: has endoparasite^op
is inverse of: intracellular endoparasite of^op

has ligand^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002019

has super-properties: has input^op

has low plasma membrane amount^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0015016

has super-properties: has plasma membrane part^op
has domain: c l 0000000^c

has major susceptibility factor^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004005

has super-properties: condition has genetic basis in^op
is inverse of: is causal susceptibility factor for^op

has material basis in gain of function germline mutation in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004001

has super-properties: condition has genetic basis in^op
is inverse of: is causal gain of function germline mutation of in^op

has material basis in germline mutation in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004003

has super-properties: condition has genetic basis in^op
is inverse of: is causal germline mutation in^op

has material basis in loss of function germline mutation in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004002

has super-properties: condition has genetic basis in^op
is inverse of: is causal loss of function germline mutation of in^op

has material basis in somatic mutation in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004004

has super-properties: condition has genetic basis in^op
is inverse of: is causal somatic mutation in^op

has member^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002351

has characteristics : irreflexive

has super-properties: has part^op
is inverse of: member of^op

has mesoparasite^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002637

has super-properties: parasitized by^op
is inverse of: mesoparasite of^op

has muscle antagonist^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002568

has super-properties: biomechanically related to^op

has muscle insertion^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002373

has super-properties: attached to^op; biomechanically related to^op
has domain: u b e r o n 0000061^c

has muscle origin^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002372

has super-properties: attached to^op; biomechanically related to^op
has domain: u b e r o n 0000061^c

has necessary component activity^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002016

A has necessary component activity B if A and B are GO molecular functions (GO_0003674), A has_component B and B is necessary for A. For example, ATPase coupled transporter activity has necessary component ATPase activity; transcript factor activity has necessary component DNA binding activity.

has super-properties: has component activity^op; positively regulated by^op

has negative regulatory component activity^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002014

By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'.

has super-properties: has regulatory component activity^op; negatively regulated by^op

has numerator^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0020202

has super-properties: has part^op
has domain: p a t o 0001470^c
has range: p a t o 0000001^c

has output^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002234

has super-properties: has participant^op
has sub-properties: has primary output^op, results in formation of anatomical entity^op
is inverse of: output of^op

has parasitoid^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002209

has super-properties: parasitized by^op
is inverse of: parasitoid of^op

has part^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000051

has characteristics : transitive

has super-properties: overlaps^op
has sub-properties: composed primarily of^op, ends with^op, has active ingredient^op, has branching part^op, has component^op, has denominator^op, has member^op, has numerator^op, has plasma membrane part^op, has skeleton^op, has subsequence^op, starts with^op
is inverse of: part of^op

has part structure that is capable of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002584

has super-properties: functionally related to^op; causal relation between material entity and a process^op

has part that occurs in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002479

has sub-properties: has end location^op, has start location^op, occurs across^op
has domain: b f o 0000003^c
has range: b f o 0000004^c

has partial material basis in germline mutation in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004006

has super-properties: condition has genetic basis in^op
is inverse of: is causal germline mutation partially giving rise to^op

has participant^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000057

has sub-properties: acts on population of^op, enabled by^op, has component participant^op, has input^op, has intermediate^op, has output^op, has primary input or output^op, has small molecule regulator^op, results in changes to anatomical or cellular structure^op
has domain: b f o 0000003^c
has range: b f o 0000002^c
is inverse of: participates in^op

has pathogen^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002557

has super-properties: host of^op
is inverse of: pathogen of^op

has phenotype^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002200

has super-properties: has phenotype or disease^op
has sub-properties: disease has basis in feature^op, has symptom^op
has domain: b f o 0000031^c or o g m s 0000031^c or u b e r o n 0000465^c
has range: u p h e n o 0001001^c
is inverse of: phenotype of^op

has phenotype or disease^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0016001

has sub-properties: has disease^op, has phenotype^op

has plasma membrane part^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002104

has super-properties: has part^op
has sub-properties: has high plasma membrane amount^op, has low plasma membrane amount^op
has domain: u b e r o n 0000465^c
has range: u b e r o n 0000465^c

has positive regulatory component activity^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002015

By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'.

has super-properties: has regulatory component activity^op; positively regulated by^op

has postsynaptic terminal in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002110

has super-properties: has synaptic terminal in^op
has sub-properties: dendrite synapsed in^op, receives synaptic input in region^op
has domain: c l 0000540^c
is inverse of: has presynaptic terminal in^op

has potential to develop into^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002387

has super-properties: has developmental potential involving^op
has sub-properties: develops into^op, has potential to directly develop into^op

has potential to developmentally contribute to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002385

has super-properties: has developmental potential involving^op
has sub-properties: developmentally contributes to^op

has potential to developmentally induce^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002386

has super-properties: has developmental potential involving^op
has sub-properties: developmentally induces^op

has potential to directly develop into^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002388

has super-properties: has potential to develop into^op
has sub-properties: develops into^op

has presynaptic terminal in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002113

has super-properties: has synaptic terminal in^op
has sub-properties: axon synapses in^op, sends synaptic output to region^op
has domain: c l 0000540^c
is inverse of: has postsynaptic terminal in^op

has primary input^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004009

has super-properties: has input^op; has primary input or output^op

has primary input or output^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004007

has super-properties: has participant^op
has sub-properties: has primary input^op, has primary output^op

has primary output^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004008

has super-properties: has output^op; has primary input or output^op

has quality^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000086

has super-properties: has characteristic^op
has range: b f o 0000019^c
is inverse of: quality of^op

has regulatory component activity^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002013

has super-properties: has component activity^op; regulated by^op
has sub-properties: has negative regulatory component activity^op, has positive regulatory component activity^op

has reservoir host^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002803

has super-properties: has host^op
is inverse of: reservoir host of^op

has role^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000087

has super-properties: has characteristic^op
has sub-properties: has application role^op, has biological role^op, has chemical role^op
has domain: b f o 0000004^c
has range: b f o 0000023^c
is inverse of: role of^op

has roost^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008509

A population of xs will possess adaptations (either evolved naturally or via artifical selection) which permit it to rest in y.

has super-properties: has habitat^op
has domain: o b i 0100026^c
has range: e n v o 01000739^c

has sensory dendrite in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013007

has super-properties: has dendrite location^op
has domain: c l 0000101^c

has skeleton^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002551

has characteristics : asymmetric, irreflexive

has super-properties: has part^op
has domain: u b e r o n 0000061^c
has range: u b e r o n 0000465^c
is inverse of: skeleton of^op

has small molecule activator^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012001

has super-properties: has small molecule regulator^op
is inverse of: is small molecule activator of^op

has small molecule inhibitor^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012002

has super-properties: has small molecule regulator^op
is inverse of: is small molecule inhibitor of^op

has small molecule regulator^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012000

has super-properties: has participant^op
has sub-properties: has small molecule activator^op, has small molecule inhibitor^op
is inverse of: is small molecule regulator of^op

has soma location^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002100

has super-properties: overlaps^op
has domain: c l 0000540^c
has range: u b e r o n 0000465^c

has start location^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002231

has super-properties: has part that occurs in^op
has domain: b f o 0000015^c
has range: b f o 0000004^c

has start sequence^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002516

has characteristics : transitive

has super-properties: has subsequence^op
is inverse of: is start sequence of^op

has subsequence^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002524

has characteristics : transitive

has super-properties: has part^op; bounds sequence of^op; overlaps sequence of^op
has sub-properties: has end sequence^op, has start sequence^op, is consecutive sequence of^op
is inverse of: is subsequence of^op

has symptom^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002452

has super-properties: has phenotype^op
has domain: o g m s 0000031^c

has synaptic IO in region^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013001

has super-properties: has synaptic terminal in^op
has sub-properties: has synaptic IO throughout^op, receives synaptic input in region^op, sends synaptic output to region^op

has synaptic IO throughout^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013004

has super-properties: has synaptic IO in region^op
has sub-properties: receives synaptic input throughout^op, sends synaptic output throughout^op

has synaptic terminal in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002130

has super-properties: overlaps^op
has sub-properties: has postsynaptic terminal in^op, has presynaptic terminal in^op, has synaptic IO in region^op
has domain: c l 0000540^c
is inverse of: has synaptic terminal of^op

has synaptic terminal of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002006

has super-properties: overlaps^op
is inverse of: has synaptic terminal in^op

has target end location^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002339

has super-properties: results in transport to from or in^op

has target start location^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002338

has super-properties: results in transport to from or in^op

has vector^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002460

has super-properties: participates in a biotic-biotic interaction with^op
is inverse of: is vector for^op

hemiparasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002237

has super-properties: parasite of^op

host of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002453

has super-properties: symbiotically interacts with^op
has sub-properties: has pathogen^op, hyperparasitized by^op, parasitized by^op, reservoir host of^op

hyperparasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002553

has super-properties: has host^op
is inverse of: hyperparasitized by^op

hyperparasitized by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002554

has super-properties: host of^op
is inverse of: hyperparasite of^op

immediate transformation of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002495

has super-properties: directly develops from^op; transformation of^op

immediately causally downstream of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002405

has super-properties: immediately preceded by^op; causally downstream of^op
is inverse of: immediately causally upstream of^op

immediately causally upstream of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002412

has super-properties: immediately precedes^op; causally upstream of^op
has sub-properties: directly regulates^op, provides input for^op
is inverse of: immediately causally downstream of^op

immediately preceded by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002087

X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)

has super-properties: preceded by^op
has sub-properties: immediately causally downstream of^op
is inverse of: immediately precedes^op

immediately precedes^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002090

X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)

has super-properties: precedes^op
has sub-properties: immediately causally upstream of^op
is inverse of: immediately preceded by^op

imports^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002340

has super-properties: transports^op

in branching relationship with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002375

has super-properties: mereotopologically related to^op
has sub-properties: branching part of^op, connecting branch of^op, distributary of^op, has branching part^op, has connecting branch^op, main stem of^op, tributary of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

in register with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002026

has super-properties: mereotopologically related to^op
has domain: image^c
has range: image^c

increases by expression quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011008

has super-properties: indirectly positively regulates quantity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

increases expression of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003003

has super-properties: directly positively regulates activity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

indirectly causally upstream of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012011

has super-properties: causally upstream of^op
has sub-properties: indirectly regulates^op

indirectly negatively regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002409

has characteristics : transitive

has super-properties: negatively regulates^op; indirectly regulates^op

indirectly negatively regulates activity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011016

has super-properties: indirectly regulates activity of^op

indirectly negatively regulates quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011023

has super-properties: indirectly regulates quantity of^op
has sub-properties: decreases by repression quantity of^op

indirectly positively regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002407

has characteristics : transitive

has super-properties: positively regulates^op; indirectly regulates^op

indirectly positively regulates activity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011013

has super-properties: indirectly regulates activity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

indirectly positively regulates quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011024

has super-properties: indirectly regulates quantity of^op
has sub-properties: increases by expression quantity of^op

indirectly regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012012

has super-properties: regulates^op; indirectly causally upstream of^op
has sub-properties: indirectly negatively regulates^op, indirectly positively regulates^op

indirectly regulates activity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011004

has super-properties: regulates activity of^op
has sub-properties: indirectly negatively regulates activity of^op, indirectly positively regulates activity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

indirectly regulates quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011022

has super-properties: regulates quantity of^op
has sub-properties: indirectly negatively regulates quantity of^op, indirectly positively regulates quantity of^op

input of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002352

has super-properties: participates in^op; functionally related to^op
is inverse of: has input^op

interacts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002434

has characteristics : symmetric

has sub-properties: biotically interacts with^op, genetically interacts with^op, molecularly interacts with^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

interacts with via parasite-host interaction^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002443

has super-properties: symbiotically interacts with^op
has sub-properties: parasite of^op, parasitized by^op

intercellular endoparasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002638

has super-properties: endoparasite of^op
is inverse of: has intercellular endoparasite^op

intracellular endoparasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002640

has super-properties: endoparasite of^op
is inverse of: has intracellular endoparasite^op

involved in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002331

has super-properties: participates in^op; involved in or involved in regulation of^op

involved in negative regulation of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002430

has super-properties: involved in regulation of^op

involved in or involved in regulation of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002431

has super-properties: acts upstream of or within^op; functionally related to^op; causal agent in process^op
has sub-properties: involved in^op, involved in regulation of^op

involved in positive regulation of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002429

has super-properties: involved in regulation of^op

involved in regulation of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002428

has super-properties: acts upstream of^op; involved in or involved in regulation of^op
has sub-properties: involved in negative regulation of^op, involved in positive regulation of^op

is active in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002432

has super-properties: overlaps^op; functionally related to^op

is agonist of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0018027

has super-properties: directly positively regulates activity of^op

is allergic trigger for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0001020

has super-properties: causes or contributes to condition^op
has domain: b f o 0000040^c
is inverse of: has allergic trigger^op

is antagonist of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0018029

has super-properties: directly negatively regulates activity of^op

is autoimmune trigger for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0001021

has super-properties: causes or contributes to condition^op
has domain: b f o 0000040^c
is inverse of: has autoimmune trigger^op

is basis for realizable^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004018

has super-properties: causally related to^op
has sub-properties: is genetic basis for condition^op
is inverse of: realizable has basis in^op

is bound by sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002523

has characteristics : transitive

has super-properties: sequentially related to^op
has sub-properties: is subsequence of^op
is inverse of: bounds sequence of^op

is causal gain of function germline mutation of in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004011

has super-properties: is genetic basis for condition^op
is inverse of: has material basis in gain of function germline mutation in^op

is causal germline mutation in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004013

has super-properties: causes condition^op; is genetic basis for condition^op
is inverse of: has material basis in germline mutation in^op

is causal germline mutation partially giving rise to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004016

has super-properties: contributes to condition^op; is genetic basis for condition^op
is inverse of: has partial material basis in germline mutation in^op

is causal loss of function germline mutation of in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004012

has super-properties: is genetic basis for condition^op
is inverse of: has material basis in loss of function germline mutation in^op

is causal somatic mutation in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004014

has super-properties: causes condition^op; is genetic basis for condition^op
is inverse of: has material basis in somatic mutation in^op

is causal susceptibility factor for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004015

has super-properties: is genetic basis for condition^op
is inverse of: has major susceptibility factor^op

is consecutive sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002520

has super-properties: has subsequence^op

is downstream of sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002529

has characteristics : transitive

has super-properties: does not overlap sequence of^op
has sub-properties: is immediately downstream of sequence of^op
is inverse of: is downstream of sequence of^op, is downstream of sequence of^op

is eaten by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002471

has super-properties: biotically interacts with^op

is end sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002519

has characteristics : transitive

has super-properties: is subsequence of^op
is inverse of: has end sequence^op

is genetic basis for condition^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004010

has super-properties: is basis for realizable^op
has sub-properties: is causal gain of function germline mutation of in^op, is causal germline mutation in^op, is causal germline mutation partially giving rise to^op, is causal loss of function germline mutation of in^op, is causal somatic mutation in^op, is causal susceptibility factor for^op
has range: b f o 0000017^c
is inverse of: condition has genetic basis in^op

is immediately downstream of sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002530

has super-properties: sequentially adjacent to^op; is downstream of sequence of^op

is immediately upstream of sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002531

has super-properties: sequentially adjacent to^op; is upstream of sequence of^op

is inverse agonist of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0018028

has super-properties: directly negatively regulates activity of^op

is killed by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002627

has super-properties: participates in a biotic-biotic interaction with^op
is inverse of: kills^op

is sequentially aligned with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002521

has characteristics : symmetric

has super-properties: sequentially related to^op

is small molecule activator of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012005

has super-properties: capable of positively regulating^op; is small molecule regulator of^op
is inverse of: has small molecule activator^op

is small molecule inhibitor of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012006

has super-properties: capable of negatively regulating^op; is small molecule regulator of^op
is inverse of: has small molecule inhibitor^op

is small molecule regulator of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012004

has super-properties: capable of regulating^op
has sub-properties: is small molecule activator of^op, is small molecule inhibitor of^op
is inverse of: has small molecule regulator^op

is start sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002517

has characteristics : transitive

has super-properties: is subsequence of^op
is inverse of: has start sequence^op

is subsequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002525

has characteristics : transitive

has super-properties: part of^op; is bound by sequence of^op; overlaps sequence of^op
has sub-properties: is end sequence of^op, is start sequence of^op
is inverse of: has subsequence^op

is substance that treats^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002606

has super-properties: capable of inhibiting or preventing pathological process^op
is inverse of: is treated by substance^op

is treated by substance^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002302

has super-properties: causally related to^op
is inverse of: is substance that treats^op

is upstream of sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002528

has characteristics : transitive

has super-properties: does not overlap sequence of^op
has sub-properties: is immediately upstream of sequence of^op

is vector for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002459

has super-properties: participates in a biotic-biotic interaction with^op
is inverse of: has vector^op

kills^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002626

has super-properties: participates in a biotic-biotic interaction with^op
is inverse of: is killed by^op

kleptoparasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008503

has super-properties: parasite of^op
is inverse of: kleptoparasitized by^op

kleptoparasitized by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008504

has super-properties: parasitized by^op
is inverse of: kleptoparasite of^op

lays eggs in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002624

has super-properties: parasite of^op; visits^op
is inverse of: has eggs laid in by^op

lays eggs on^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0008507

has super-properties: visits^op
is inverse of: has eggs laid on by^op

lumen of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002571

has super-properties: part of^op
has sub-properties: luminal space of^op
has range: b f o 0000040^c

luminal space of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002572

has super-properties: lumen of^op
has domain: b f o 0000141^c

main stem of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002381

has super-properties: part of^op; in branching relationship with^op

member of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002350

has super-properties: part of^op
is inverse of: has member^op

mereotopologically related to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002323

has sub-properties: 2D boundary of^op, attached to part of^op, coincident with^op, colocalizes with^op, connected to^op, connects^op, continuous with^op, has 2D boundary^op, in branching relationship with^op, in register with^op, overlaps^op, spatially disjoint from^op

mesoparasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002636

has super-properties: parasite of^op
is inverse of: has mesoparasite^op

molecularly interacts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002436

has characteristics : symmetric

has super-properties: interacts with^op
has sub-properties: directly regulates activity of^op, myristoylates^op, phosphorylates^op, ubiquitinates^op

mutualistically interacts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002442

has super-properties: symbiotically interacts with^op
has sub-properties: pollinated by^op, pollinates^op

myristoylated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0018003

is inverse of: myristoylates^op

myristoylates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0018002

has super-properties: molecularly interacts with^op
is inverse of: myristoylated by^op

negatively regulated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002335

has super-properties: regulated by^op
has sub-properties: has negative regulatory component activity^op
is inverse of: negatively regulates^op

negatively regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002212

has super-properties: regulates^op; causally upstream of, negative effect^op
has sub-properties: directly negatively regulates^op, indirectly negatively regulates^op
is inverse of: negatively regulated by^op

negatively regulates characteristic^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0019002

has super-properties: regulates characteristic^op

negatively regulates in another organism^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012014

has super-properties: regulates in another organism^op

obligate parasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002227

has super-properties: parasite of^op

occurrent part of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002012

has super-properties: part of^op; causally upstream of or within^op
has domain: b f o 0000003^c
has range: b f o 0000003^c

occurs across^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002021

has super-properties: has part that occurs in^op
has sub-properties: results in transport across^op

output of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002353

has super-properties: participates in^op; functionally related to^op
has sub-properties: formed as result of^op
is inverse of: has output^op

overlaps^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002131

has characteristics : symmetric

has super-properties: mereotopologically related to^op
has sub-properties: conduit for^op, contributes to morphology of^op, determined by part of^op, fasciculates with^op, has dendrite location^op, has fasciculating neuron projection^op, has part^op, has soma location^op, has synaptic terminal in^op, has synaptic terminal of^op, is active in^op, overlaps sequence of^op, part of^op, partially overlaps^op, spatially coextensive with^op

overlaps sequence of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002526

has characteristics : symmetric

has super-properties: overlaps^op; sequentially related to^op
has sub-properties: has subsequence^op, is subsequence of^op

parasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002444

has super-properties: interacts with via parasite-host interaction^op; has host^op
has sub-properties: ectoparasite of^op, endoparasite of^op, facultative parasite of^op, hemiparasite of^op, kleptoparasite of^op, lays eggs in^op, mesoparasite of^op, obligate parasite of^op, parasitoid of^op, root parasite of^op, stem parasite of^op
is inverse of: parasitized by^op

parasitized by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002445

has super-properties: interacts with via parasite-host interaction^op; host of^op
has sub-properties: has ectoparasite^op, has eggs laid in by^op, has endoparasite^op, has mesoparasite^op, has parasitoid^op, kleptoparasitized by^op
is inverse of: parasite of^op

parasitoid of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002208

has super-properties: parasite of^op
is inverse of: has parasitoid^op

part of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000050

has characteristics : transitive

has super-properties: overlaps^op
has sub-properties: active ingredient in^op, bounding layer of^op, branching part of^op, determined by^op, ends^op, is subsequence of^op, lumen of^op, main stem of^op, member of^op, occurrent part of^op, skeleton of^op, starts^op, subcluster of^op
is inverse of: has part^op

part of developmental precursor of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002287

has super-properties: developmentally succeeded by^op

part of structure that is capable of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002329

has super-properties: functionally related to^op
has sub-properties: contributes to^op

partially overlaps^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002151

has super-properties: overlaps^op

participates in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000056

has sub-properties: input of^op, involved in^op, output of^op, partner in^op
has domain: b f o 0000002^c
has range: b f o 0000003^c
is inverse of: has participant^op

participates in a abiotic-biotic interaction with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002446

has super-properties: biotically interacts with^op

participates in a biotic-biotic interaction with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002574

has super-properties: biotically interacts with^op
has sub-properties: allelopath of^op, has vector^op, is killed by^op, is vector for^op, kills^op, symbiotically interacts with^op, trophically interacts with^op, visited by^op, visits^op
has domain: o b i 0100026^c
has range: o b i 0100026^c

partner in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002461

has super-properties: participates in^op
has sub-properties: subject participant in^op, target participant in^op

pathogen of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002556

has super-properties: has host^op
is inverse of: has pathogen^op

phenotype of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002201

has characteristics : functional

is inverse of: has phenotype^op

phosphorylates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002447

has super-properties: molecularly interacts with^op

pollinated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002456

has super-properties: mutualistically interacts with^op
is inverse of: pollinates^op

pollinates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002455

has super-properties: mutualistically interacts with^op
is inverse of: pollinated by^op

positively regulated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002336

has super-properties: regulated by^op
has sub-properties: has necessary component activity^op, has positive regulatory component activity^op
is inverse of: positively regulates^op

positively regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002213

has characteristics : transitive

has super-properties: regulates^op; causally upstream of, positive effect^op
has sub-properties: directly positively regulates^op, indirectly positively regulates^op
is inverse of: positively regulated by^op

positively regulates characteristic^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0019001

has super-properties: regulates characteristic^op

positively regulates in another organism^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012013

has super-properties: regulates in another organism^op

preceded by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000062

has characteristics : transitive

has super-properties: ends after^op
has sub-properties: causally downstream of^op, immediately preceded by^op
has domain: b f o 0000003^c
has range: b f o 0000003^c
is inverse of: precedes^op

precedes^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/BFO_0000063

has characteristics : transitive

has super-properties: temporally related to^op
has sub-properties: causally upstream of^op, immediately precedes^op
has domain: b f o 0000003^c
has range: b f o 0000003^c
is inverse of: preceded by^op

preyed upon by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002458

has super-properties: trophically interacts with^op
is inverse of: preys on^op

preys on^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002439

has super-properties: trophically interacts with^op
is inverse of: preyed upon by^op

process has causal agent^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002608

has super-properties: causally related to^op
is inverse of: causal agent in process^op

proper distributary of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002382

has super-properties: distributary of^op

proper tributary of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002383

has super-properties: tributary of^op

provides input for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002413

has super-properties: immediately causally upstream of^op; transitively provides input for^op

provides nutrients for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002469

has super-properties: biotically interacts with^op
is inverse of: acquires nutrients from^op

quality of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000080

has super-properties: characteristic of^op
is inverse of: has quality^op

realizable has basis in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004017

has super-properties: causally related to^op
has sub-properties: disease has basis in^op
is inverse of: is basis for realizable^op

realized in response to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0009501

has super-properties: causally related to^op
has domain: b f o 0000017^c
has range: b f o 0000015^c

realized in response to stimulus^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0004028

has super-properties: causally related to^op
has domain: b f o 0000017^c
has range: b f o 0000040^c

receives input from^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002485

has super-properties: connected to^op
has sub-properties: synapsed by^op
is inverse of: sends output to^op

receives synaptic input from neuron^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013008

has super-properties: synapsed by^op
is inverse of: sends synaptic output to cell^op

receives synaptic input in region^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013002

has super-properties: has postsynaptic terminal in^op; has synaptic IO in region^op
has sub-properties: receives synaptic input throughout^op

receives synaptic input throughout^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013005

has super-properties: receives synaptic input in region^op; has synaptic IO throughout^op

regulated by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002334

has characteristics : transitive

has super-properties: causally downstream of or within^op
has sub-properties: directly regulated by^op, has regulatory component activity^op, negatively regulated by^op, positively regulated by^op
has domain: b f o 0000015^c
has range: b f o 0000015^c
is inverse of: regulates^op

regulates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002211

has characteristics : transitive

has super-properties: causally upstream of^op
has sub-properties: directly regulates^op, indirectly regulates^op, negatively regulates^op, positively regulates^op
has domain: b f o 0000015^c
has range: b f o 0000015^c
is inverse of: regulated by^op

regulates activity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011002

has super-properties: causally influences^op
has sub-properties: directly regulates activity of^op, indirectly regulates activity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

regulates characteristic^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0019000

has super-properties: causally related to^op
has sub-properties: negatively regulates characteristic^op, positively regulates characteristic^op
has domain: b f o 0000015^c
has range: p a t o 0000001^c

regulates in another organism^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002010

has super-properties: causally upstream of or within^op
has sub-properties: negatively regulates in another organism^op, positively regulates in another organism^op
has domain: b f o 0000015^c
has range: b f o 0000015^c

regulates levels of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002332

has super-properties: functionally related to^op
has domain: b f o 0000015^c
has range: b f o 0000040^c

regulates quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011003

has super-properties: causally influences^op
has sub-properties: directly regulates quantity of^op, indirectly regulates quantity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

related via exposure to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002244

has super-properties: causally related to^op
has sub-properties: has exposure medium^op, has exposure receptor^op, has exposure route^op, has exposure stimulus^op, has exposure transport path^op
has domain: c o b 0001000^c

related via localization to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002337

has sub-properties: results in transport along^op, results in transport to from or in^op, transports or maintains localization of^op
has domain: b f o 0000015^c
has range: b f o 0000002^c

removes input for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012010

has super-properties: causally upstream of, negative effect^op

represses expression of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0003002

has super-properties: directly negatively regulates activity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

reservoir host of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002802

A reservoir is a population, species or community (assemblage of different species in a given geographic area) in which a microorganism naturally occurs and is indefinitely maintained. Some zoonotic pathogens, particularly bacterial pathogens, may also have environmental reservoirs. Microorganisms with multiple reservoir species may be indefinitely maintained across the community of species even if they are not always present in each individual reservoir species. In the reservoir species or community, the microorganism may cause either asymptomatic infection or disease and this may vary among individuals. A pathogen may also be more genetically diverse in its reservoir host than in other taxa, in part because the pathogen is endemic to reservoir hosts.

has super-properties: host of^op
is inverse of: has reservoir host^op

results in acquisition of features of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002315

has super-properties: results in developmental progression of^op; results in changes to anatomical or cellular structure^op
has range: u b e r o n 0000061^c

results in adhesion of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012007

has super-properties: results in changes to anatomical or cellular structure^op

results in assembly of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002588

has super-properties: results in formation of anatomical entity^op; results in organization of^op

results in breakdown of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002586

has super-properties: has input^op
has sub-properties: results in catabolism of^op, results in disassembly of^op

results in catabolism of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002589

has super-properties: results in breakdown of^op

results in changes to anatomical or cellular structure^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0040036

has super-properties: has participant^op
has sub-properties: results in acquisition of features of^op, results in adhesion of^op, results in closure of^op, results in development of^op, results in ending of^op, results in growth of^op, results in maturation of^op, results in morphogenesis of^op, results in movement of^op, results in organization of^op, results in structural organization of^op, transports or maintains localization of^op

results in closure of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002585

has super-properties: results in developmental progression of^op; results in changes to anatomical or cellular structure^op

results in commitment to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002348

has super-properties: results in developmental progression of^op
has range: c l 0000000^c

results in determination of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002349

has super-properties: results in developmental progression of^op
has range: c l 0000000^c

results in development of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002296

has super-properties: results in developmental progression of^op; results in changes to anatomical or cellular structure^op

results in developmental induction of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002357

has super-properties: results in developmental progression of^op

results in developmental progression of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002295

has super-properties: developmentally related to^op
has sub-properties: results in acquisition of features of^op, results in closure of^op, results in commitment to^op, results in determination of^op, results in development of^op, results in developmental induction of^op, results in ending of^op, results in formation of anatomical entity^op, results in growth of^op, results in maturation of^op, results in morphogenesis of^op, results in specification of^op, results in structural organization of^op
has domain: g o 0008150^c
has range: u b e r o n 0001062^c

results in developmental regression of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002301

has super-properties: results in ending of^op

results in disappearance of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002300

has super-properties: results in ending of^op

results in disassembly of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002590

has super-properties: results in breakdown of^op; results in organization of^op

results in ending of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002552

has super-properties: results in developmental progression of^op; results in changes to anatomical or cellular structure^op
has sub-properties: results in developmental regression of^op, results in disappearance of^op

results in formation of anatomical entity^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002297

has super-properties: has output^op; results in developmental progression of^op
has sub-properties: results in assembly of^op, results in synthesis of^op
is inverse of: formed as result of^op

results in fusion of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0012008

has super-properties: results in organization of^op

results in growth of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002343

has super-properties: results in developmental progression of^op; results in changes to anatomical or cellular structure^op

results in maturation of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002299

has super-properties: results in developmental progression of^op; results in changes to anatomical or cellular structure^op

results in morphogenesis of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002298

has super-properties: results in developmental progression of^op; results in changes to anatomical or cellular structure^op

results in movement of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002565

has super-properties: results in changes to anatomical or cellular structure^op

results in organization of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002592

has super-properties: results in changes to anatomical or cellular structure^op
has sub-properties: results in assembly of^op, results in disassembly of^op, results in fusion of^op, results in remodeling of^op

results in remodeling of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002591

has super-properties: has input^op; results in organization of^op

results in specification of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002356

has super-properties: results in developmental progression of^op
has range: c l 0000000^c

results in structural organization of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002355

has super-properties: results in developmental progression of^op; results in changes to anatomical or cellular structure^op

results in synthesis of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002587

has super-properties: results in formation of anatomical entity^op

results in transport across^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002342

has super-properties: occurs across^op; results in transport to from or in^op

results in transport along^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002341

has super-properties: related via localization to^op

results in transport to from or in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002344

has super-properties: related via localization to^op
has sub-properties: has target end location^op, has target start location^op, results in transport across^op

role of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0000081

has super-properties: characteristic of^op
is inverse of: has role^op

root parasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002236

has super-properties: parasite of^op

sends output to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002486

has super-properties: connected to^op
has sub-properties: synapsed to^op
is inverse of: receives input from^op

sends synaptic output throughout^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013006

has super-properties: sends synaptic output to region^op; has synaptic IO throughout^op

sends synaptic output to cell^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013009

Not restricting range to 'cell' - object may be a muscle containing a cell targeted by the neuron.

has super-properties: synapsed to^op
is inverse of: receives synaptic input from neuron^op

sends synaptic output to region^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0013003

has super-properties: has presynaptic terminal in^op; has synaptic IO in region^op
has sub-properties: sends synaptic output throughout^op

sequentially adjacent to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002515

has super-properties: does not overlap sequence of^op
has sub-properties: is immediately downstream of sequence of^op, is immediately upstream of sequence of^op

sequentially related to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002514

has sub-properties: bounds sequence of^op, does not overlap sequence of^op, is bound by sequence of^op, is sequentially aligned with^op, overlaps sequence of^op
has domain: r o 0002532^c
has range: r o 0002532^c

simultaneous with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002082

t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2)

has characteristics : symmetric, transitive

has super-properties: before or simultaneous with^op

skeleton of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002576

has super-properties: part of^op
has domain: u b e r o n 0000061^c
has range: u b e r o n 0000061^c
is inverse of: has skeleton^op

spatially coextensive with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002379

has super-properties: overlaps^op

spatially disjoint from^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002163

has super-properties: mereotopologically related to^op
has sub-properties: adjacent to^op

stabilizes quantity of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0011015

has super-properties: directly positively regulates quantity of^op
has domain: b f o 0000040^c
has range: b f o 0000040^c

starts^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002223

has super-properties: part of^op; temporally related to^op
is inverse of: starts with^op

starts before^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002089

has characteristics : transitive

has super-properties: temporally related to^op

starts during^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002091

X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))

has super-properties: temporally related to^op
has sub-properties: happens during^op
has domain: b f o 0000003^c
has range: b f o 0000003^c
is inverse of: during which starts^op

starts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002224

has characteristics : transitive

has super-properties: has part^op; temporally related to^op
is inverse of: starts^op

stem parasite of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002235

has super-properties: parasite of^op

subcluster of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0015003

has characteristics : transitive

has super-properties: part of^op

subject participant in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002462

has super-properties: partner in^op

supplies^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002178

has super-properties: connected to^op
has sub-properties: directly supplies and drains^op, vessel supplies blood to^op

surrounded by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002219

has super-properties: adjacent to^op
is inverse of: surrounds^op

surrounds^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002221

has super-properties: adjacent to^op
is inverse of: surrounded by^op

symbiotically interacts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002440

has characteristics : symmetric

has super-properties: participates in a biotic-biotic interaction with^op
has sub-properties: commensually interacts with^op, epiphyte of^op, has epiphyte^op, has host^op, host of^op, interacts with via parasite-host interaction^op, mutualistically interacts with^op

synapsed by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002103

has super-properties: receives input from^op
has sub-properties: receives synaptic input from neuron^op, synapsed_by_via_type_III_bouton^op, synapsed_by_via_type_II_bouton^op, synapsed_by_via_type_Ib_bouton^op, synapsed_by_via_type_Is_bouton^op
has range: c l 0000540^c or (part of^op some c l 0000540^c)
is inverse of: synapsed to^op

synapsed to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002120

N1 synapsed_to some N2 Expands to: N1 SubclassOf ( has_part some ( ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( ‘synapse ; GO:0045202’ that has_part some ( ‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))

has super-properties: sends output to^op
has sub-properties: sends synaptic output to cell^op, synapsed_via_type_III_bouton_to^op, synapsed_via_type_II_bouton_to^op, synapsed_via_type_Ib_bouton_to^op, synapsed_via_type_Is_bouton_to^op
has domain: c l 0000540^c or (part of^op some c l 0000540^c)
is inverse of: synapsed by^op

synapsed_by_via_type_Ib_bouton^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002109

Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type Ib terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))

has super-properties: synapsed by^op
is inverse of: synapsed_via_type_Ib_bouton_to^op

synapsed_by_via_type_II_bouton^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002108

Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type II terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))

has super-properties: synapsed by^op
is inverse of: synapsed_via_type_II_bouton_to^op

synapsed_by_via_type_III_bouton^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002115

Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type III terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))

has super-properties: synapsed by^op
is inverse of: synapsed_via_type_III_bouton_to^op

synapsed_by_via_type_Is_bouton^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002112

Expands to: has_part some ('presynaptic membrane' that part_of some ('synapse' that has_part some ('type Is terminal button' that has_part some 'postsynaptic membrane' that part_of some ?Y)))))

has super-properties: synapsed by^op
is inverse of: synapsed_via_type_Is_bouton_to^op

synapsed_via_type_Ib_bouton_to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002105

Expands to: has_part some ('type Ib terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))

has super-properties: synapsed to^op
is inverse of: synapsed_by_via_type_Ib_bouton^op

synapsed_via_type_II_bouton_to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002107

Expands to: has_part some ('type II terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))

has super-properties: synapsed to^op
is inverse of: synapsed_by_via_type_II_bouton^op

synapsed_via_type_III_bouton_to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002114

Expands to: has_part some ('type III terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))

has super-properties: synapsed to^op
is inverse of: synapsed_by_via_type_III_bouton^op

synapsed_via_type_Is_bouton_to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002106

Expands to: has_part some ('type Is terminal button' that has_part some ('pre-synaptic membrane' that part_of some ('synapse' that has_part some ('post-synaptic membrane' that part_of some ?Y))))

has super-properties: synapsed to^op
is inverse of: synapsed_by_via_type_Is_bouton^op

target participant in^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002463

has super-properties: partner in^op

temporally related to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002222

A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations.

has sub-properties: before or simultaneous with^op, during which ends^op, during which starts^op, ends^op, ends after^op, ends during^op, ends with^op, precedes^op, starts^op, starts before^op, starts during^op, starts with^op
has domain: b f o 0000003^c
has range: b f o 0000003^c

towards^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002503

has super-properties: depends on^op

transformation of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002494

has characteristics : transitive

has super-properties: develops from^op
has sub-properties: immediate transformation of^op

transitively provides input for^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002414

has characteristics : transitive

has super-properties: causally upstream of or within, positive effect^op
has sub-properties: provides input for^op
has domain: b f o 0000015^c
has range: b f o 0000015^c

transmitted by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002451

has super-properties: ecologically related to^op

transports^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002020

has super-properties: transports or maintains localization of^op
has sub-properties: exports^op, imports^op

transports or maintains localization of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002313

has super-properties: related via localization to^op; results in changes to anatomical or cellular structure^op
has sub-properties: transports^op

tributary of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002376

has super-properties: connected to^op; in branching relationship with^op
has sub-properties: proper tributary of^op

trophically interacts with^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002438

has super-properties: participates in a biotic-biotic interaction with^op
has sub-properties: preyed upon by^op, preys on^op

ubiquitinates^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002480

has super-properties: molecularly interacts with^op

vessel drains blood from^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0020102

has super-properties: drains^op
has domain: u b e r o n 0001981^c
has range: u b e r o n 0000061^c

vessel supplies blood to^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0020101

has super-properties: supplies^op
has domain: u b e r o n 0001981^c
has range: u b e r o n 0000061^c

visited by^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002619

has super-properties: participates in a biotic-biotic interaction with^op
has sub-properties: has eggs laid in by^op, has eggs laid on by^op, has flowers visited by^op
is inverse of: visits^op

visits^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002618

has super-properties: participates in a biotic-biotic interaction with^op
has sub-properties: lays eggs in^op, lays eggs on^op, visits flowers of^op
is inverse of: visited by^op

visits flowers of^op back to ToC or Object Property ToC

IRI: http://purl.obolibrary.org/obo/RO_0002622

has super-properties: visits^op
is inverse of: has flowers visited by^op

This HTML document was obtained by processing the OWL ontology source code through LODE, Live OWL Documentation Environment, developed by Silvio Peroni .

Table of Content

Object Properties

2D boundary ofop back to ToC or Object Property ToC

acquires nutrients fromop back to ToC or Object Property ToC

active ingredient inop back to ToC or Object Property ToC

acts on population ofop back to ToC or Object Property ToC

acts upstream ofop back to ToC or Object Property ToC

acts upstream of or withinop back to ToC or Object Property ToC

acts upstream of or within, negative effectop back to ToC or Object Property ToC

acts upstream of or within, positive effectop back to ToC or Object Property ToC

acts upstream of, negative effectop back to ToC or Object Property ToC

acts upstream of, positive effectop back to ToC or Object Property ToC

adjacent toop back to ToC or Object Property ToC

allelopath ofop back to ToC or Object Property ToC

ameliorates conditionop back to ToC or Object Property ToC

anabranch ofop back to ToC or Object Property ToC

attached toop back to ToC or Object Property ToC

attached to part ofop back to ToC or Object Property ToC

axon synapses inop back to ToC or Object Property ToC

beforeop back to ToC or Object Property ToC

before or simultaneous withop back to ToC or Object Property ToC

biomechanically related toop back to ToC or Object Property ToC

biotically interacts withop back to ToC or Object Property ToC

bounding layer ofop back to ToC or Object Property ToC

bounds sequence ofop back to ToC or Object Property ToC

branching part ofop back to ToC or Object Property ToC

capable ofop back to ToC or Object Property ToC

capable of inhibiting or preventing pathological processop back to ToC or Object Property ToC

capable of negatively regulatingop back to ToC or Object Property ToC

capable of part ofop back to ToC or Object Property ToC

capable of positively regulatingop back to ToC or Object Property ToC

capable of regulatingop back to ToC or Object Property ToC

capable of upregulating or causing pathological processop back to ToC or Object Property ToC

causal agent in processop back to ToC or Object Property ToC

causal relation between entitiesop back to ToC or Object Property ToC

causal relation between material entity and a processop back to ToC or Object Property ToC

causal relation between processesop back to ToC or Object Property ToC

causal relationship with disease as subjectop back to ToC or Object Property ToC

causally downstream ofop back to ToC or Object Property ToC

causally downstream of or withinop back to ToC or Object Property ToC

causally influenced byop back to ToC or Object Property ToC

causally influencesop back to ToC or Object Property ToC

causally related toop back to ToC or Object Property ToC

causally upstream ofop back to ToC or Object Property ToC

causally upstream of or withinop back to ToC or Object Property ToC

causally upstream of or within, negative effectop back to ToC or Object Property ToC

causally upstream of or within, positive effectop back to ToC or Object Property ToC

causally upstream of, negative effectop back to ToC or Object Property ToC

causally upstream of, positive effectop back to ToC or Object Property ToC

causes conditionop back to ToC or Object Property ToC

causes or contributes to conditionop back to ToC or Object Property ToC

characteristic ofop back to ToC or Object Property ToC

characteristic of part ofop back to ToC or Object Property ToC

child nucleus ofop back to ToC or Object Property ToC

child nucleus of in hermaphroditeop back to ToC or Object Property ToC

child nucleus of in maleop back to ToC or Object Property ToC

co-roosts withop back to ToC or Object Property ToC

coincident withop back to ToC or Object Property ToC

colocalizes withop back to ToC or Object Property ToC

commensually interacts withop back to ToC or Object Property ToC

composed primarily ofop back to ToC or Object Property ToC

condition ameliorated byop back to ToC or Object Property ToC

condition exacerbated byop back to ToC or Object Property ToC

condition has genetic basis inop back to ToC or Object Property ToC

conduit forop back to ToC or Object Property ToC

confers advantage inop back to ToC or Object Property ToC

confers susceptibility to conditionop back to ToC or Object Property ToC

connected toop back to ToC or Object Property ToC

connecting branch ofop back to ToC or Object Property ToC

connectsop back to ToC or Object Property ToC

constitutively upstream ofop back to ToC or Object Property ToC

continuous withop back to ToC or Object Property ToC

contributes toop back to ToC or Object Property ToC

contributes to conditionop back to ToC or Object Property ToC

contributes to frequency of conditionop back to ToC or Object Property ToC

contributes to morphology ofop back to ToC or Object Property ToC

contributes to severity of conditionop back to ToC or Object Property ToC

creates habitat forop back to ToC or Object Property ToC

decreases by repression quantity ofop back to ToC or Object Property ToC

dendrite synapsed inop back to ToC or Object Property ToC

2D boundary of^op back to ToC or Object Property ToC

acquires nutrients from^op back to ToC or Object Property ToC

active ingredient in^op back to ToC or Object Property ToC

acts on population of^op back to ToC or Object Property ToC

acts upstream of^op back to ToC or Object Property ToC

acts upstream of or within^op back to ToC or Object Property ToC

acts upstream of or within, negative effect^op back to ToC or Object Property ToC

acts upstream of or within, positive effect^op back to ToC or Object Property ToC

acts upstream of, negative effect^op back to ToC or Object Property ToC

acts upstream of, positive effect^op back to ToC or Object Property ToC

adjacent to^op back to ToC or Object Property ToC

allelopath of^op back to ToC or Object Property ToC

ameliorates condition^op back to ToC or Object Property ToC

anabranch of^op back to ToC or Object Property ToC

attached to^op back to ToC or Object Property ToC

attached to part of^op back to ToC or Object Property ToC

axon synapses in^op back to ToC or Object Property ToC

before^op back to ToC or Object Property ToC

before or simultaneous with^op back to ToC or Object Property ToC

biomechanically related to^op back to ToC or Object Property ToC

biotically interacts with^op back to ToC or Object Property ToC

bounding layer of^op back to ToC or Object Property ToC

bounds sequence of^op back to ToC or Object Property ToC

branching part of^op back to ToC or Object Property ToC

capable of^op back to ToC or Object Property ToC

capable of inhibiting or preventing pathological process^op back to ToC or Object Property ToC

capable of negatively regulating^op back to ToC or Object Property ToC

capable of part of^op back to ToC or Object Property ToC

capable of positively regulating^op back to ToC or Object Property ToC

capable of regulating^op back to ToC or Object Property ToC

capable of upregulating or causing pathological process^op back to ToC or Object Property ToC

causal agent in process^op back to ToC or Object Property ToC

causal relation between entities^op back to ToC or Object Property ToC

causal relation between material entity and a process^op back to ToC or Object Property ToC

causal relation between processes^op back to ToC or Object Property ToC

causal relationship with disease as subject^op back to ToC or Object Property ToC

causally downstream of^op back to ToC or Object Property ToC

causally downstream of or within^op back to ToC or Object Property ToC

causally influenced by^op back to ToC or Object Property ToC

causally influences^op back to ToC or Object Property ToC

causally related to^op back to ToC or Object Property ToC

causally upstream of^op back to ToC or Object Property ToC

causally upstream of or within^op back to ToC or Object Property ToC

causally upstream of or within, negative effect^op back to ToC or Object Property ToC

causally upstream of or within, positive effect^op back to ToC or Object Property ToC

causally upstream of, negative effect^op back to ToC or Object Property ToC

causally upstream of, positive effect^op back to ToC or Object Property ToC

causes condition^op back to ToC or Object Property ToC

causes or contributes to condition^op back to ToC or Object Property ToC

characteristic of^op back to ToC or Object Property ToC

characteristic of part of^op back to ToC or Object Property ToC

child nucleus of^op back to ToC or Object Property ToC

child nucleus of in hermaphrodite^op back to ToC or Object Property ToC

child nucleus of in male^op back to ToC or Object Property ToC

co-roosts with^op back to ToC or Object Property ToC

coincident with^op back to ToC or Object Property ToC

colocalizes with^op back to ToC or Object Property ToC

commensually interacts with^op back to ToC or Object Property ToC

composed primarily of^op back to ToC or Object Property ToC

condition ameliorated by^op back to ToC or Object Property ToC

condition exacerbated by^op back to ToC or Object Property ToC

condition has genetic basis in^op back to ToC or Object Property ToC

conduit for^op back to ToC or Object Property ToC

confers advantage in^op back to ToC or Object Property ToC

confers susceptibility to condition^op back to ToC or Object Property ToC

connected to^op back to ToC or Object Property ToC

connecting branch of^op back to ToC or Object Property ToC

connects^op back to ToC or Object Property ToC

constitutively upstream of^op back to ToC or Object Property ToC

continuous with^op back to ToC or Object Property ToC

contributes to^op back to ToC or Object Property ToC

contributes to condition^op back to ToC or Object Property ToC

contributes to frequency of condition^op back to ToC or Object Property ToC

contributes to morphology of^op back to ToC or Object Property ToC

contributes to severity of condition^op back to ToC or Object Property ToC

creates habitat for^op back to ToC or Object Property ToC

decreases by repression quantity of^op back to ToC or Object Property ToC

dendrite synapsed in^op back to ToC or Object Property ToC

depends on^op back to ToC or Object Property ToC

destabilizes quantity of^op back to ToC or Object Property ToC