@prefix rdf: . @prefix : . @prefix dc: . @prefix obo: . @prefix owl: . @prefix xml: . @prefix xsd: . @prefix foaf: . @prefix rdfs: . @prefix skos: . @prefix swrl: . @prefix chebi: . @prefix swrlb: . @prefix terms: . @prefix owl2xml: . @prefix protege: . @prefix oboInOwl: . @prefix ncbitaxon: . protege:defaultLanguage a owl:AnnotationProperty . obo:BFO_0000001 obo:BFO_0000179 "entity" ; obo:BFO_0000180 "Entity" ; obo:IAO_0000112 "Julius Caesar"@en, "Verdi’s Requiem"@en, "the Second World War"@en, "your body mass index"@en ; obo:IAO_0000116 "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81"@en, "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"@en ; obo:IAO_0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])"@en ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "entity"@en ; rdfs:subClassOf owl:Thing . obo:BFO_0000002 obo:BFO_0000179 "continuant" ; obo:BFO_0000180 "Continuant" ; obo:IAO_0000115 "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ; obo:IAO_0000116 "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240"@en, "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants"@en ; obo:IAO_0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])"@en ; obo:IAO_0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])"@en, "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])"@en, "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])"@en ; obo:IAO_0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] ", "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] ", "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] ", "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "continuant"@en ; rdfs:subClassOf obo:BFO_0000001 ; owl:disjointWith obo:BFO_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:BFO_0000003 ] . obo:BFO_0000003 obo:BFO_0000179 "occurrent" ; obo:BFO_0000180 "Occurrent" ; obo:IAO_0000115 "An entity that has temporal parts and that happens, unfolds or develops through time."@en ; obo:IAO_0000116 "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region"@en, "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players."@en, "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process."@en, "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." ; obo:IAO_0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])"@en ; obo:IAO_0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])"@en, "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] ", "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "occurrent"@en ; rdfs:subClassOf obo:BFO_0000001 ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:BFO_0000002 ] . obo:BFO_0000004 obo:BFO_0000179 "ic" ; obo:BFO_0000180 "IndependentContinuant" ; obo:IAO_0000112 "a chair"@en, "a heart"@en, "a leg"@en, "a molecule"@en, "a spatial region"@en, "an atom"@en, "an orchestra."@en, "an organism"@en, "the bottom right portion of a human torso"@en, "the interior of your mouth"@en ; obo:IAO_0000115 "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ; obo:IAO_0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])"@en, "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] ", "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] ", "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " ; a owl:Class ; rdfs:comment "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything."@en ; rdfs:isDefinedBy ; rdfs:label "independent continuant"@en ; rdfs:subClassOf obo:BFO_0000002 ; owl:disjointWith obo:BFO_0000020, obo:BFO_0000031 . obo:BFO_0000006 obo:BFO_0000179 "s-region" ; obo:BFO_0000180 "SpatialRegion" ; obo:IAO_0000116 "BFO 2 Reference: Spatial regions do not participate in processes."@en, "Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional."@en ; obo:IAO_0000600 "A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])"@en ; obo:IAO_0000601 "All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])"@en ; obo:IAO_0000602 "(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] ", "(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "spatial region"@en ; rdfs:subClassOf obo:BFO_0000141 ; owl:disjointWith obo:BFO_0000029, obo:BFO_0000140 . obo:BFO_0000008 obo:BFO_0000179 "t-region" ; obo:BFO_0000180 "TemporalRegion" ; obo:IAO_0000116 "Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional"@en ; obo:IAO_0000600 "A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])"@en ; obo:IAO_0000601 "All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])"@en, "Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])"@en ; obo:IAO_0000602 "(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] ", "(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] ", "(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "temporal region"@en ; rdfs:subClassOf obo:BFO_0000003 ; owl:disjointWith obo:BFO_0000011, obo:BFO_0000015, obo:BFO_0000035 . obo:BFO_0000009 obo:BFO_0000179 "2d-s-region" ; obo:BFO_0000180 "TwoDimensionalSpatialRegion" ; obo:IAO_0000112 "an infinitely thin plane in space."@en, "the surface of a sphere-shaped part of space"@en ; obo:IAO_0000600 "A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])"@en ; obo:IAO_0000602 "(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "two-dimensional spatial region"@en ; rdfs:subClassOf obo:BFO_0000006 ; owl:disjointWith obo:BFO_0000028 . obo:BFO_0000011 obo:BFO_0000179 "st-region" ; obo:BFO_0000180 "SpatiotemporalRegion" ; obo:IAO_0000112 "the spatiotemporal region occupied by a human life"@en, "the spatiotemporal region occupied by a process of cellular meiosis."@en, "the spatiotemporal region occupied by the development of a cancer tumor"@en ; obo:IAO_0000600 "A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])"@en ; obo:IAO_0000601 "All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])"@en, "Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])"@en, "Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])"@en, "Every spatiotemporal region occupies_spatiotemporal_region itself."@en, "Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])"@en ; obo:IAO_0000602 "(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] ", "(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] ", "(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] ", "(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] ", "(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "spatiotemporal region"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:BFO_0000015 obo:BFO_0000179 "process" ; obo:BFO_0000180 "Process" ; obo:IAO_0000112 "a process of cell-division, \\ a beating of the heart"@en, "a process of meiosis"@en, "a process of sleeping"@en, "the course of a disease"@en, "the flight of a bird"@en, "the life of an organism"@en, "your process of aging."@en ; obo:IAO_0000115 "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ; obo:IAO_0000116 "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)"@en ; obo:IAO_0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " ; a owl:Class ; rdfs:comment "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t."@en ; rdfs:isDefinedBy ; rdfs:label "process"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:BFO_0000016 obo:BFO_0000179 "disposition" ; obo:BFO_0000180 "Disposition" ; obo:IAO_0000112 "an atom of element X has the disposition to decay to an atom of element Y"@en, "certain people have a predisposition to colon cancer"@en, "children are innately disposed to categorize objects in certain ways."@en, "the cell wall is disposed to filter chemicals in endocytosis and exocytosis"@en ; obo:IAO_0000116 "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type."@en ; obo:IAO_0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])"@en ; obo:IAO_0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] ", "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "disposition"@en ; rdfs:subClassOf obo:BFO_0000017 ; owl:disjointWith obo:BFO_0000023 . obo:BFO_0000017 obo:BFO_0000179 "realizable" ; obo:BFO_0000180 "RealizableEntity" ; obo:IAO_0000112 "the disposition of this piece of metal to conduct electricity."@en, "the disposition of your blood to coagulate"@en, "the function of your reproductive organs"@en, "the role of being a doctor"@en, "the role of this boundary to delineate where Utah and Colorado meet"@en ; obo:IAO_0000115 "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ; obo:IAO_0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])"@en ; obo:IAO_0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] ", "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "realizable entity"@en ; rdfs:subClassOf obo:BFO_0000020 ; owl:disjointWith obo:BFO_0000019 . obo:BFO_0000018 obo:BFO_0000179 "0d-s-region" ; obo:BFO_0000180 "ZeroDimensionalSpatialRegion" ; obo:IAO_0000600 "A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])"@en ; obo:IAO_0000602 "(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "zero-dimensional spatial region"@en ; rdfs:subClassOf obo:BFO_0000006 ; owl:disjointWith obo:BFO_0000028 . obo:BFO_0000019 obo:BFO_0000179 "quality" ; obo:BFO_0000180 "Quality" ; obo:IAO_0000112 "the ambient temperature of this portion of air"@en, "the color of a tomato"@en, "the length of the circumference of your waist"@en, "the mass of this piece of gold."@en, "the shape of your nose"@en, "the shape of your nostril"@en ; obo:IAO_0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])"@en ; obo:IAO_0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] ", "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "quality"@en ; rdfs:subClassOf obo:BFO_0000020 . obo:BFO_0000020 obo:BFO_0000179 "sdc" ; obo:BFO_0000180 "SpecificallyDependentContinuant" ; obo:IAO_0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key"@en, "of one-sided specifically dependent continuants: the mass of this tomato"@en, "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates."@en, "the disposition of this fish to decay"@en, "the function of this heart: to pump blood"@en, "the mutual dependence of proton donors and acceptors in chemical reactions [79"@en, "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction"@en, "the pink color of a medium rare piece of grilled filet mignon at its center"@en, "the role of being a doctor"@en, "the shape of this hole."@en, "the smell of this portion of mozzarella"@en ; obo:IAO_0000115 "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ; obo:IAO_0000116 "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc."@en ; obo:IAO_0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " ; a owl:Class ; rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ; rdfs:isDefinedBy ; rdfs:label "specifically dependent continuant"@en ; rdfs:subClassOf obo:BFO_0000002 ; owl:disjointWith obo:BFO_0000031 . obo:BFO_0000023 obo:BFO_0000179 "role" ; obo:BFO_0000180 "Role" ; obo:IAO_0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married."@en, "the priest role"@en, "the role of a boundary to demarcate two neighboring administrative territories"@en, "the role of a building in serving as a military target"@en, "the role of a stone in marking a property boundary"@en, "the role of subject in a clinical trial"@en, "the student role"@en ; obo:IAO_0000115 "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts."@en ; obo:IAO_0000116 "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives."@en ; obo:IAO_0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "role"@en ; rdfs:subClassOf obo:BFO_0000017 . obo:BFO_0000024 obo:BFO_0000179 "fiat-object-part" ; obo:BFO_0000180 "FiatObjectPart" ; obo:IAO_0000112 "or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29"@en, "the FMA:regional parts of an intact human body."@en, "the Western hemisphere of the Earth"@en, "the division of the brain into regions"@en, "the division of the planet into hemispheres"@en, "the dorsal and ventral surfaces of the body"@en, "the upper and lower lobes of the left lung"@en ; obo:IAO_0000116 "BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions"@en ; obo:IAO_0000600 "b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])"@en ; obo:IAO_0000602 "(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "fiat object part"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:BFO_0000026 obo:BFO_0000179 "1d-s-region" ; obo:BFO_0000180 "OneDimensionalSpatialRegion" ; obo:IAO_0000112 "an edge of a cube-shaped portion of space."@en ; obo:IAO_0000600 "A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])"@en ; obo:IAO_0000602 "(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "one-dimensional spatial region"@en ; rdfs:subClassOf obo:BFO_0000006 ; owl:disjointWith obo:BFO_0000028 . obo:BFO_0000027 obo:BFO_0000179 "object-aggregate" ; obo:BFO_0000180 "ObjectAggregate" ; obo:IAO_0000112 "a collection of cells in a blood biobank."@en, "a swarm of bees is an aggregate of members who are linked together through natural bonds"@en, "a symphony orchestra"@en, "an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)"@en, "defined by fiat: the aggregate of members of an organization"@en, "defined through physical attachment: the aggregate of atoms in a lump of granite"@en, "defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container"@en, "defined via attributive delimitations such as: the patients in this hospital"@en, "the aggregate of bearings in a constant velocity axle joint"@en, "the aggregate of blood cells in your body"@en, "the nitrogen atoms in the atmosphere"@en, "the restaurants in Palo Alto"@en, "your collection of Meissen ceramic plates."@en ; obo:IAO_0000116 "An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects ", "BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee)."@en ; obo:IAO_0000119 "ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158." ; obo:IAO_0000600 "b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])"@en ; obo:IAO_0000602 "(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "object aggregate"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:BFO_0000028 obo:BFO_0000179 "3d-s-region" ; obo:BFO_0000180 "ThreeDimensionalSpatialRegion" ; obo:IAO_0000112 "a cube-shaped region of space"@en, "a sphere-shaped region of space,"@en ; obo:IAO_0000600 "A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])"@en ; obo:IAO_0000602 "(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "three-dimensional spatial region"@en ; rdfs:subClassOf obo:BFO_0000006 . obo:BFO_0000029 obo:BFO_0000179 "site" ; obo:BFO_0000180 "Site" ; obo:IAO_0000112 "Manhattan Canyon)"@en, "a hole in the interior of a portion of cheese"@en, "a rabbit hole"@en, "an air traffic control region defined in the airspace above an airport"@en, "the Grand Canyon"@en, "the Piazza San Marco"@en, "the cockpit of an aircraft"@en, "the hold of a ship"@en, "the interior of a kangaroo pouch"@en, "the interior of the trunk of your car"@en, "the interior of your bedroom"@en, "the interior of your office"@en, "the interior of your refrigerator"@en, "the lumen of your gut"@en, "your left nostril (a fiat part – the opening – of your left nasal cavity)"@en ; obo:IAO_0000600 "b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])"@en ; obo:IAO_0000602 "(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "site"@en ; rdfs:subClassOf obo:BFO_0000141 . obo:BFO_0000030 obo:BFO_0000179 "object" ; obo:BFO_0000180 "Object" ; obo:IAO_0000112 "atom"@en, "cell"@en, "cells and organisms"@en, "engineered artifacts"@en, "grain of sand"@en, "molecule"@en, "organelle"@en, "organism"@en, "planet"@en, "solid portions of matter"@en, "star"@en ; obo:IAO_0000116 "BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting."@en, "BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below)."@en, "BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47"@en, "BFO 2 Reference: an object is a maximal causally unified material entity"@en, "BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74"@en ; obo:IAO_0000600 "b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])"@en ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "object"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:BFO_0000031 obo:BFO_0000179 "gdc" ; obo:BFO_0000180 "GenericallyDependentContinuant" ; obo:IAO_0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity."@en, "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop"@en, "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule."@en ; obo:IAO_0000115 "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en ; obo:IAO_0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " ; a owl:Class ; rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en ; rdfs:isDefinedBy ; rdfs:label "generically dependent continuant"@en ; rdfs:subClassOf obo:BFO_0000002 . obo:BFO_0000034 obo:BFO_0000179 "function" ; obo:BFO_0000180 "Function" ; obo:IAO_0000112 "the function of a hammer to drive in nails"@en, "the function of a heart pacemaker to regulate the beating of a heart through electricity"@en, "the function of amylase in saliva to break down starch into sugar"@en ; obo:IAO_0000116 "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc."@en ; obo:IAO_0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "function"@en ; rdfs:subClassOf obo:BFO_0000016 . obo:BFO_0000035 obo:BFO_0000179 "p-boundary" ; obo:BFO_0000180 "ProcessBoundary" ; obo:IAO_0000112 "the boundary between the 2nd and 3rd year of your life."@en ; obo:IAO_0000115 "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en ; obo:IAO_0000601 "Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])"@en ; obo:IAO_0000602 "(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] ", "(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "process boundary"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:BFO_0000038 obo:BFO_0000179 "1d-t-region" ; obo:BFO_0000180 "OneDimensionalTemporalRegion" ; obo:IAO_0000112 "the temporal region during which a process occurs."@en ; obo:IAO_0000116 "BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks)."@en ; obo:IAO_0000600 "A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])"@en ; obo:IAO_0000602 "(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "one-dimensional temporal region"@en ; rdfs:subClassOf obo:BFO_0000008 ; owl:disjointWith obo:BFO_0000148 . obo:BFO_0000040 obo:BFO_0000179 "material" ; obo:BFO_0000180 "MaterialEntity" ; obo:IAO_0000112 "a flame"@en, "a forest fire"@en, "a human being"@en, "a hurricane"@en, "a photon"@en, "a puff of smoke"@en, "a sea wave"@en, "a tornado"@en, "an aggregate of human beings."@en, "an energy wave"@en, "an epidemic"@en, "the undetached arm of a human being"@en ; obo:IAO_0000115 "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ; obo:IAO_0000116 "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60"@en, "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity."@en, "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here."@en ; obo:IAO_0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])"@en ; obo:IAO_0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])"@en, "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])"@en ; obo:IAO_0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] ", "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] ", "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "material entity"@en ; rdfs:subClassOf obo:BFO_0000004 ; owl:disjointWith obo:BFO_0000141 . obo:BFO_0000050 obo:IAO_0000111 "is part of"@en ; obo:IAO_0000112 "my brain is part of my body (continuant parthood, two material entities)"@en, "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"@en, "this day is part of this year (occurrent parthood)"@en ; obo:IAO_0000115 "a core relation that holds between a part and its whole"@en ; obo:IAO_0000116 "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."@en, "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en, """Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."""@en ; obo:IAO_0000118 "part_of"@en ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "part of"@en ; rdfs:seeAlso "http://www.obofoundry.org/ro/#OBO_REL:part_of" ; owl:inverseOf obo:BFO_0000051 . obo:BFO_0000051 obo:IAO_0000111 "has part"@en ; obo:IAO_0000112 "my body has part my brain (continuant parthood, two material entities)"@en, "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"@en, "this year has part this day (occurrent parthood)"@en ; obo:IAO_0000115 "a core relation that holds between a whole and its part"@en ; obo:IAO_0000116 "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."@en, "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en, """Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."""@en ; obo:IAO_0000118 "has_part"@en ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "has part"@en . obo:BFO_0000054 obo:IAO_0000111 "realized in"@en ; obo:IAO_0000112 "this disease is realized in this disease course"@en, "this fragility is realized in this shattering"@en, "this investigator role is realized in this investigation"@en ; obo:IAO_0000118 "is realized by"@en, "realized_in"@en ; obo:IAO_0000600 "[copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])"@en ; a owl:ObjectProperty ; rdfs:comment "Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ; rdfs:domain obo:BFO_0000017 ; rdfs:isDefinedBy ; rdfs:label "realized in"@en ; rdfs:range obo:BFO_0000015 ; owl:inverseOf obo:BFO_0000055 . obo:BFO_0000055 obo:IAO_0000111 "realizes"@en ; obo:IAO_0000112 "this disease course realizes this disease"@en, "this investigation realizes this investigator role"@en, "this shattering realizes this fragility"@en ; obo:IAO_0000600 "to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])"@en ; a owl:ObjectProperty ; rdfs:comment "Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process" ; rdfs:domain obo:BFO_0000015 ; rdfs:isDefinedBy ; rdfs:label "realizes"@en ; rdfs:range obo:BFO_0000017 . obo:BFO_0000062 obo:IAO_0000111 "preceded by"@en ; obo:IAO_0000115 "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ; obo:IAO_0000116 "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."@en ; obo:IAO_0000118 "is preceded by"@en, "preceded_by"@en ; obo:IAO_0000412 ; terms:source "http://www.obofoundry.org/ro/#OBO_REL:preceded_by" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "preceded by"@en ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002086 ; owl:inverseOf obo:BFO_0000063 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000062 ), (obo:RO_0002091 obo:BFO_0000062 ), (obo:RO_0002092 obo:BFO_0000062 ) . obo:BFO_0000063 obo:IAO_0000111 "precedes"@en ; obo:IAO_0000115 "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ; obo:IAO_0000412 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "precedes"@en ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002222 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000063 ), (obo:RO_0002092 obo:BFO_0000063 ) . obo:BFO_0000066 obo:IAO_0000111 "occurs in"@en ; obo:IAO_0000115 "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ; obo:IAO_0000118 "occurs_in"@en, "unfolds in"@en, "unfolds_in"@en ; a owl:ObjectProperty ; rdfs:comment "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant" ; rdfs:domain obo:BFO_0000003 ; rdfs:isDefinedBy ; rdfs:label "occurs in"@en ; rdfs:range obo:BFO_0000004 ; owl:inverseOf obo:BFO_0000067 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000066 ), (obo:BFO_0000066 obo:BFO_0000050 ) . obo:BFO_0000067 obo:IAO_0000111 "site of"@en ; obo:IAO_0000115 "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ; a owl:ObjectProperty ; rdfs:comment "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant" ; rdfs:isDefinedBy ; rdfs:label "contains process"@en . obo:BFO_0000140 obo:BFO_0000179 "cf-boundary" ; obo:BFO_0000180 "ContinuantFiatBoundary" ; obo:IAO_0000115 "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en ; obo:IAO_0000116 "BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions."@en, "BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29"@en, "Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions."@en ; obo:IAO_0000601 "Every continuant fiat boundary is located at some spatial region at every time at which it exists"@en ; obo:IAO_0000602 "(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "continuant fiat boundary"@en ; rdfs:subClassOf obo:BFO_0000141 . obo:BFO_0000141 obo:BFO_0000179 "immaterial" ; obo:BFO_0000180 "ImmaterialEntity" ; obo:IAO_0000116 "BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10"@en ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "immaterial entity"@en ; rdfs:subClassOf obo:BFO_0000004 . obo:BFO_0000142 obo:BFO_0000179 "1d-cf-boundary" ; obo:BFO_0000180 "OneDimensionalContinuantFiatBoundary" ; obo:IAO_0000112 "The Equator"@en, "all geopolitical boundaries"@en, "all lines of latitude and longitude"@en, "the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin."@en, "the median sulcus of your tongue"@en ; obo:IAO_0000600 "a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])"@en ; obo:IAO_0000602 "(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "one-dimensional continuant fiat boundary"@en ; rdfs:subClassOf obo:BFO_0000140 ; owl:disjointWith obo:BFO_0000146, obo:BFO_0000147 . obo:BFO_0000144 obo:BFO_0000179 "process-profile" ; obo:BFO_0000180 "ProcessProfile" ; obo:IAO_0000112 "On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels"@en, "One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance."@en, "The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on."@en ; obo:IAO_0000115 "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en ; obo:IAO_0000600 "b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])"@en ; obo:IAO_0000602 "(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] ", "(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "process profile"@en ; rdfs:subClassOf obo:BFO_0000015 ; owl:disjointWith obo:BFO_0000182 . obo:BFO_0000145 obo:BFO_0000179 "r-quality" ; obo:BFO_0000180 "RelationalQuality" ; obo:IAO_0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married."@en, "a marriage bond, an instance of requited love, an obligation between one person and another."@en ; obo:IAO_0000115 "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en ; obo:IAO_0000602 "(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "relational quality"@en ; rdfs:subClassOf obo:BFO_0000019 . obo:BFO_0000146 obo:BFO_0000179 "2d-cf-boundary" ; obo:BFO_0000180 "TwoDimensionalContinuantFiatBoundary" ; obo:IAO_0000600 "a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])"@en ; obo:IAO_0000602 "(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "two-dimensional continuant fiat boundary"@en ; rdfs:subClassOf obo:BFO_0000140 . obo:BFO_0000147 obo:BFO_0000179 "0d-cf-boundary" ; obo:BFO_0000180 "ZeroDimensionalContinuantFiatBoundary" ; obo:IAO_0000112 "the geographic North Pole"@en, "the point of origin of some spatial coordinate system."@en, "the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet"@en ; obo:IAO_0000116 "zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona."@en ; obo:IAO_0000600 "a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])"@en ; obo:IAO_0000602 "(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "zero-dimensional continuant fiat boundary"@en ; rdfs:subClassOf obo:BFO_0000140 . obo:BFO_0000148 obo:BFO_0000179 "0d-t-region" ; obo:BFO_0000180 "ZeroDimensionalTemporalRegion" ; obo:IAO_0000112 "a temporal region that is occupied by a process boundary"@en, "right now"@en, "the moment at which a child is born"@en, "the moment at which a finger is detached in an industrial accident"@en, "the moment of death."@en ; obo:IAO_0000118 "temporal instant."@en ; obo:IAO_0000600 "A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])"@en ; obo:IAO_0000602 "(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "zero-dimensional temporal region"@en ; rdfs:subClassOf obo:BFO_0000008 . obo:BFO_0000179 obo:IAO_0000115 "Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification."@en ; obo:IAO_0000232 "Really of interest to developers only"@en ; a owl:AnnotationProperty ; rdfs:label "BFO OWL specification label"@en ; rdfs:subPropertyOf rdfs:label . obo:BFO_0000180 obo:IAO_0000115 "Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2"@en ; obo:IAO_0000119 "Person:Alan Ruttenberg" ; obo:IAO_0000232 "Really of interest to developers only"@en ; a owl:AnnotationProperty ; rdfs:label "BFO CLIF specification label"@en ; rdfs:subPropertyOf rdfs:label . obo:BFO_0000182 obo:BFO_0000179 "history" ; obo:BFO_0000180 "History" ; obo:IAO_0000600 "A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])"@en ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "history"@en ; rdfs:subClassOf obo:BFO_0000015 . obo:CHEBI_15882 obo:IAO_0000115 "An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C6H6O" ; chebi:inchi "InChI=1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H" ; chebi:inchikey "ISWSIDIOOBJBQZ-UHFFFAOYSA-N" ; chebi:mass "94.11120" ; chebi:monoisotopicmass "94.04186" ; chebi:smiles "Oc1ccccc1" ; oboInOwl:hasAlternativeId "CHEBI:14777", "CHEBI:25966", "CHEBI:43543", "CHEBI:8071" ; oboInOwl:hasDbXref "Beilstein:969616", "CAS:108-95-2", "DrugBank:DB03255", "Drug_Central:4266", "Gmelin:2794", "HMDB:HMDB0000228", "KEGG:C00146", "KEGG:C15584", "KEGG:D00033", "KEGG:D06536", "KNApSAcK:C00002664", "PDBeChem:IPH", "PMID:12058733", "PMID:16953321", "PMID:17852157", "PMID:19029204", "PMID:20886261", "PMID:21492257", "PMID:21689881", "PMID:21809019", "PMID:21822930", "Reaxys:969616", "UM-BBD_compID:c0128", "Wikipedia:Phenol" ; oboInOwl:hasExactSynonym "PHENOL", "Phenol", "phenol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Benzenol", "Carbolsaeure", "Hydroxybenzene", "Karbolsaeure", "Oxybenzene", "PhOH", "Phenic acid", "Phenylic acid", "Phenylic alcohol", "acide carbolique", "acide phenique", "carbolic acid" ; oboInOwl:id "CHEBI:15882" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "phenol" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_16199 obo:IAO_0000115 "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "CH4N2O" ; chebi:inchi "InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)" ; chebi:inchikey "XSQUKJJJFZCRTK-UHFFFAOYSA-N" ; chebi:mass "60.05534" ; chebi:monoisotopicmass "60.03236" ; chebi:smiles "NC(N)=O" ; oboInOwl:hasAlternativeId "CHEBI:15292", "CHEBI:27218", "CHEBI:46379", "CHEBI:9888" ; oboInOwl:hasDbXref "Beilstein:635724", "CAS:57-13-6", "DrugBank:DB03904", "Drug_Central:4264", "ECMDB:ECMDB04172", "Gmelin:1378", "HMDB:HMDB0000294", "KEGG:C00086", "KEGG:D00023", "KNApSAcK:C00007314", "MetaCyc:UREA", "PDBeChem:URE", "PMID:18037357", "PMID:22770225", "PPDB:1728", "Reaxys:635724", "UM-BBD_compID:c0165", "Wikipedia:Urea", "YMDB:YMDB00003" ; oboInOwl:hasExactSynonym "UREA", "Urea", "urea" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1728", "Carbamide", "E927b", "H2NC(O)NH2", "Harnstoff", "Karbamid", "carbamide", "carbonyldiamide", "ur", "uree" ; oboInOwl:id "CHEBI:16199" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "urea" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_16412 obo:IAO_0000115 "Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria)." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "CHEBI:14520", "CHEBI:25062", "CHEBI:6494" ; oboInOwl:hasDbXref "KEGG:C00338", "PMID:15589368", "PMID:24186868", "PMID:24506665", "PMID:24642373", "PMID:24659348" ; oboInOwl:hasExactSynonym "Lipopolysaccharide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "LPS", "lipopolysaccharides" ; oboInOwl:id "CHEBI:16412" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "lipopolysaccharide" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_16670 obo:IAO_0000115 "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "(C2H2NOR)nC2H3NOR" ; oboInOwl:hasAlternativeId "CHEBI:14753", "CHEBI:25906", "CHEBI:7990" ; oboInOwl:hasDbXref "KEGG:C00012" ; oboInOwl:hasExactSynonym "Peptide", "peptides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Peptid", "peptido", "peptidos" ; oboInOwl:id "CHEBI:16670" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "peptide" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_16842 obo:IAO_0000115 "An aldehyde resulting from the formal oxidation of methanol." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "CH2O" ; chebi:inchi "InChI=1S/CH2O/c1-2/h1H2" ; chebi:inchikey "WSFSSNUMVMOOMR-UHFFFAOYSA-N" ; chebi:mass "30.02598" ; chebi:monoisotopicmass "30.01056" ; chebi:smiles "[H]C([H])=O" ; oboInOwl:hasAlternativeId "CHEBI:14274", "CHEBI:24077", "CHEBI:337763", "CHEBI:5142" ; oboInOwl:hasDbXref "Beilstein:1209228", "CAS:50-00-0", "DrugBank:DB03843", "Drug_Central:3244", "Gmelin:445", "HMDB:HMDB0001426", "KEGG:C00067", "KEGG:D00017", "MetaCyc:FORMALDEHYDE", "PDBeChem:FOR", "PMID:110589", "PMID:12686735", "PMID:15091529", "PMID:16423181", "PMID:17618393", "PMID:18837732", "PMID:25042713", "PMID:7381846", "PMID:7548723", "PMID:7689168", "PMID:7896413", "PMID:9686972", "PPDB:359", "Reaxys:1209228", "UM-BBD_compID:c0122", "Wikipedia:Formaldehyde" ; oboInOwl:hasExactSynonym "FORMALDEHYDE", "Formaldehyde", "formaldehyde" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "FORMALIN", "Formaldehyd", "Formalin", "Methanal", "Methylene oxide", "Oxomethane", "Oxomethylene" ; oboInOwl:id "CHEBI:16842" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "formaldehyde" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_17076 obo:IAO_0000115 "A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class" ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C21H39N7O12" ; chebi:inchi "InChI=1S/C21H39N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+/m0/s1" ; chebi:inchikey "UCSJYZPVAKXKNQ-HZYVHMACSA-N" ; chebi:mass "581.57434" ; chebi:monoisotopicmass "581.26567" ; chebi:smiles "CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@@H](O[C@@H](C)[C@]1(O)C=O)O[C@H]1[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]1NC(N)=N" ; oboInOwl:hasAlternativeId "CHEBI:15119", "CHEBI:26784", "CHEBI:45745", "CHEBI:9284" ; oboInOwl:hasDbXref "Beilstein:74498", "CAS:57-92-1", "DrugBank:DB01082", "Drug_Central:2481", "HMDB:HMDB0015214", "KEGG:C00413", "KEGG:D08531", "MetaCyc:STREPTOMYCIN", "PDBeChem:SRY", "PMID:11228320", "PMID:11905029", "PMID:12118520", "PMID:13030054", "PMID:13116094", "PMID:13136149", "PMID:13596285", "PMID:13691614", "PMID:13985260", "PMID:13990247", "PMID:14623118", "PMID:14828344", "PMID:14852338", "PMID:14939639", "PMID:15081082", "PMID:15137533", "PMID:15207172", "PMID:15686853", "PMID:15736038", "PMID:16904706", "PMID:17105735", "PMID:17238915", "PMID:17429930", "PMID:18173084", "PMID:18916143", "PMID:19052412", "PMID:19335957", "PMID:21350946", "PMID:21362244", "PMID:21593257", "PMID:21937264", "PMID:22101040", "Pesticides:streptomycin", "Reaxys:74498", "Wikipedia:Streptomycin" ; oboInOwl:hasExactSynonym "N,N'''-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine", "STREPTOMYCIN" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside", "Kantrex", "SM", "[2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}", "streomycin", "streptomycin" ; oboInOwl:id "CHEBI:17076" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "streptomycin" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_17716 obo:IAO_0000115 "A glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1->4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C12H22O11" ; chebi:inchi "InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11?,12+/m1/s1" ; chebi:inchikey "GUBGYTABKSRVRQ-QKKXKWKRSA-N" ; chebi:mass "342.297" ; chebi:monoisotopicmass "342.11621" ; chebi:smiles "OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:10296", "CHEBI:10380", "CHEBI:14497", "CHEBI:22460", "CHEBI:22760", "CHEBI:25005", "CHEBI:27755", "CHEBI:613009" ; oboInOwl:hasDbXref "Beilstein:1292745", "CAS:63-42-3", "GlyGen:G74621DY", "GlyTouCan:G74621DY", "Gmelin:882872", "KEGG:C00243", "KEGG:D00046", "KEGG:G10504", "KNApSAcK:C00001136", "PMID:1292745", "PMID:17329833", "PMID:18300214", "PMID:19053747", "PMID:19846069", "PMID:19913595", "PMID:20094999", "PMID:20503067", "PMID:20699559", "PMID:20873837", "PMID:20961532", "PMID:21403918", "PMID:2432147", "PMID:2456994", "PMID:28690131", "PMID:28807538", "PMID:6194884", "PMID:7574700", "Reaxys:1292745" ; oboInOwl:hasExactSynonym "beta-D-galactopyranosyl-(1->4)-D-glucopyranose", "lactose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-lactose", "(Gal)1 (Glc)1", "1-beta-D-Galactopyranosyl-4-D-glucopyranose", "4-(beta-D-galactosido)-D-glucose", "4-O-beta-D-galactopyranosyl-D-glucose", "D-lactose", "Galbeta1-4Glc", "Lac", "Laktobiose", "Laktose", "Milchzucker", "Milk sugar", "WURCS=2.0/2,2,1/[a2122h-1x_1-5][a2112h-1b_1-5]/1-2/a4-b1", "beta-D-Gal-(1->4)-D-Glc", "beta-D-Galp-(1->4)-D-Glcp", "beta-Gal1,4-Glc", "lactobiose", "milk sugar" ; oboInOwl:id "CHEBI:17716" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "lactose" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_17833 obo:IAO_0000115 "Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "CHEBI:14293", "CHEBI:24206", "CHEBI:24212", "CHEBI:5306" ; oboInOwl:hasDbXref "CAS:1403-66-3", "DrugBank:DB00798", "KEGG:C00505" ; oboInOwl:hasExactSynonym "4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Gentamicin", "gentamycins" ; oboInOwl:id "CHEBI:17833" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "gentamycin" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_17992 obo:IAO_0000115 "A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C12H22O11" ; chebi:inchi "InChI=1S/C12H22O11/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1" ; chebi:inchikey "CZMRCDWAGMRECN-UGDNZRGBSA-N" ; chebi:mass "342.29650" ; chebi:monoisotopicmass "342.11621" ; chebi:smiles "OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:15128", "CHEBI:26812", "CHEBI:45795", "CHEBI:9314" ; oboInOwl:hasDbXref "Beilstein:90825", "CAS:57-50-1", "DrugBank:DB02772", "Drug_Central:4610", "Gmelin:97695", "HMDB:HMDB0000258", "KEGG:C00089", "KEGG:D00025", "KEGG:D06533", "KEGG:G00370", "KNApSAcK:C00001151", "MetaCyc:SUCROSE", "PDBeChem:SUC", "PMID:11021636", "PMID:11093712", "PMID:11111003", "PMID:12065720", "PMID:12706980", "PMID:13508893", "PMID:15291457", "PMID:15660210", "PMID:15792978", "PMID:15845855", "PMID:16228482", "PMID:16304615", "PMID:16313996", "PMID:16525719", "PMID:16660545", "PMID:16663947", "PMID:16665852", "PMID:17233733", "PMID:17439666", "PMID:17597061", "PMID:18625236", "PMID:19199566", "PMID:19726178", "PMID:21703290", "PMID:21972845", "PMID:22085755", "PMID:22311778", "PMID:22404833", "PMID:22751876", "Reaxys:1435311", "Reaxys:90825", "Wikipedia:Sucrose" ; oboInOwl:hasExactSynonym "SUCROSE", "Sucrose", "beta-D-fructofuranosyl alpha-D-glucopyranoside", "sucrose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside", "Cane sugar", "Saccharose", "Sacharose", "White sugar", "beta-D-Fruf-(2<->1)-alpha-D-Glcp", "sacarosa", "table sugar" ; oboInOwl:id "CHEBI:17992" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "sucrose" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_23367 obo:IAO_0000115 "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ; obo:IAO_0000412 ; oboInOwl:hasExactSynonym "molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "entidad molecular", "entidades moleculares", "entite moleculaire", "molecular entities", "molekulare Entitaet" ; oboInOwl:id "CHEBI:23367" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "molecular entity" ; rdfs:subClassOf obo:CHEBI_24431 . obo:CHEBI_24431 obo:IAO_0000115 "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." ; obo:IAO_0000412 ; oboInOwl:hasExactSynonym "chemical entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24431" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "chemical entity" ; rdfs:subClassOf obo:BFO_0000040 . obo:CHEBI_26710 obo:IAO_0000115 "An inorganic chloride salt having sodium(1+) as the counterion." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "ClNa" ; chebi:inchi "InChI=1S/ClH.Na/h1H;/q;+1/p-1" ; chebi:inchikey "FAPWRFPIFSIZLT-UHFFFAOYSA-M" ; chebi:mass "58.44247" ; chebi:monoisotopicmass "57.95862" ; chebi:smiles "[Na+].[Cl-]" ; oboInOwl:hasDbXref "Beilstein:3534976", "CAS:7647-14-5", "Gmelin:13673", "KEGG:C13563", "KEGG:D02056", "MetaCyc:NACL", "PPDB:595", "Reaxys:3534976", "Wikipedia:Sodium_Chloride" ; oboInOwl:hasExactSynonym "sodium chloride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kochsalz", "NaCl", "Natriumchlorid", "chlorure de sodium", "cloruro sodico", "common salt", "halite", "natrii chloridum", "rock salt", "salt", "table salt" ; oboInOwl:id "CHEBI:26710" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "sodium chloride" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_2877 obo:IAO_0000115 "A dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C14H18N2O5" ; chebi:inchi "InChI=1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1" ; chebi:inchikey "IAOZJIPTCAWIRG-QWRGUYRKSA-N" ; chebi:mass "294.304" ; chebi:monoisotopicmass "294.12157" ; chebi:smiles "C(C[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(=O)OC)=O)N)(=O)O" ; oboInOwl:hasAlternativeId "CHEBI:45047" ; oboInOwl:hasDbXref "Beilstein:2223850", "CAS:22839-47-0", "DrugBank:DB00168", "HMDB:HMDB0001894", "KEGG:C11045", "KEGG:D02381", "PDBeChem:PME", "PMID:1771173", "PMID:2013754", "PMID:21150094", "PMID:21372000", "PMID:22354473", "PMID:24355796", "PMID:24925367", "PMID:24944748", "PMID:24965331", "PMID:25431414", "PMID:25543075", "PMID:25786106", "PMID:25951455", "PMID:25991916", "PMID:26015492", "PMID:26099025", "PMID:26159964", "PMID:26247507", "PMID:26308194", "PMID:26321723", "PMID:26377607", "PMID:26582819", "PMID:26593524", "PMID:26912665", "PMID:27015640", "PMID:27038223", "PMID:27088715", "PMID:27127997", "PMID:27216413", "PMID:27298583", "PMID:27492574", "PMID:27565676", "PMID:27614095", "PMID:27640132", "PMID:27699780", "PMID:27728881", "PMID:27840415", "PMID:27845306", "PMID:30000570", "PMID:37291632", "PMID:37297402", "PMID:37454665", "Patent:US3492131", "Reaxys:2223850", "Wikipedia:Aspartame" ; oboInOwl:hasExactSynonym "Aspartame", "methyl L-alpha-aspartyl-L-phenylalaninate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-methyl N-L-alpha-aspartyl-L-phenylalanate", "3-Amino-N-(alpha-carboxyphenethyl)succinamic acid N-methyl ester", "3-Amino-N-(alpha-methoxycarbonylphenethyl) succinamic acid", "AminoSweet", "Asp-phe-ome", "Aspartylphenylalanine methyl ester", "E 951", "L-Aspartyl-L-phenylalanine methyl ester", "NutraSweet", "Sanecta", "aspartam", "aspartamo", "aspartamum" ; oboInOwl:id "CHEBI:2877" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "aspartame" ; rdfs:subClassOf obo:CHEBI_16670 . obo:CHEBI_30911 obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C6H14O6" ; chebi:mass "182.172" ; chebi:monoisotopicmass "182.07904" ; oboInOwl:hasAlternativeId "CHEBI:15093", "CHEBI:26724", "CHEBI:26726", "CHEBI:33795", "CHEBI:33796", "CHEBI:9201" ; oboInOwl:hasDbXref "Beilstein:1721909", "Gmelin:83165", "Wikipedia:Sorbitol" ; oboInOwl:hasExactSynonym "glucitol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Sorbitol", "gulitol", "rel-(2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol" ; oboInOwl:id "CHEBI:30911" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "glucitol" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_32111 obo:IAO_0000115 "A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C7H5NO3S" ; chebi:inchi "InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)" ; chebi:inchikey "CVHZOJJKTDOEJC-UHFFFAOYSA-N" ; chebi:mass "183.18500" ; chebi:monoisotopicmass "182.99901" ; chebi:smiles "O=C1NS(=O)(=O)c2ccccc12" ; oboInOwl:hasAlternativeId "CHEBI:49717" ; oboInOwl:hasDbXref "Beilstein:6888", "CAS:81-07-2", "Gmelin:4203", "HMDB:HMDB0029723", "KEGG:D01085", "MetaCyc:CPD-5581", "PDBeChem:LSA", "PMID:24456165", "PMID:24549104", "PMID:24739358", "PMID:24780866", "Reaxys:6888", "Wikipedia:Saccharin" ; oboInOwl:hasExactSynonym "1,2-benzisothiazol-3(2H)-one 1,1-dioxide", "Saccharin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1-Dioxo-1,2-benzisothiazol-3(2H)-one", "1,1-Dioxo-1,2-dihydro-benzo[d]isothiazol-3-one", "1,2-Benzisothiazol-3(2H)-one 1,1-dioxide", "1,2-Benzisothiazolin-3-one 1,1-dioxide", "1,2-Dihydro-2-ketobenzisosulfonazole", "1,2-Dihydro-2-ketobenzisosulphonazole", "2,3-Dihydro-3-oxobenzisosulfonazole", "2,3-Dihydro-3-oxobenzisosulphonazole", "3-Hydroxybenzisothiazole-S,S-dioxide", "Anhydro-o-sulfaminebenzoic acid", "Benzo-2-sulphimide", "Benzoic acid sulfimide", "Benzoic sulfimide", "Benzoic sulphimide", "Benzosulfimide", "Benzosulphimide", "Benzoylsulfonic Imide", "Saccharimide", "Saccharine", "o-Benzoic sulfimide", "o-Benzosulfimide", "o-Sulfobenzimide", "o-Sulfobenzoic acid imide" ; oboInOwl:id "CHEBI:32111" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "saccharin" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_33130 obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "AlH3O3", "H3AlO3" ; chebi:inchi "InChI=1S/Al.3H2O/h;3*1H2/q+3;;;/p-3" ; chebi:inchikey "WNROFYMDJYEPJX-UHFFFAOYSA-K" ; chebi:mass "78.00356" ; chebi:monoisotopicmass "77.98976" ; chebi:smiles "[H]O[Al](O[H])O[H]" ; oboInOwl:hasAlternativeId "CHEBI:30193", "CHEBI:31195" ; oboInOwl:hasDbXref "CAS:21645-51-2", "Drug_Central:4250", "Gmelin:22216", "KEGG:C13391", "KEGG:D02859", "Wikipedia:Aluminum_Hydroxide" ; oboInOwl:hasExactSynonym "aluminium(3+) hydroxide", "aluminium(III) hydroxide", "trihydroxidoaluminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Al(OH)3", "Aluminiumhydroxid", "Aluminum hydroxide" ; oboInOwl:id "CHEBI:33130" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "aluminium hydroxide" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_37586 obo:IAO_0000412 ; oboInOwl:hasDbXref "CAS:7632-05-5", "Wikipedia:Sodium_phosphates" ; oboInOwl:hasExactSynonym "sodium phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphoric acid, sodium salt", "sodium orthophosphate", "sodium phosphates", "sodium salt of phosphoric acid" ; oboInOwl:id "CHEBI:37586" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "sodium phosphate" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_52071 obo:IAO_0000115 "A (1->6)-alpha-D-glucan which has extra branching consisting of (1->2), (1->3) or (1->4) linkages." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "CAS:9004-54-0", "KEGG:C00372", "KEGG:D00060", "KEGG:D06541", "KEGG:G10502", "PMID:8154046" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(1,6-alpha-D-Glucosyl)m", "(1,6-alpha-D-Glucosyl)m+1", "(1,6-alpha-D-Glucosyl)n", "(1,6-alpha-D-Glucosyl)n+1", "1,6-alpha-D-Glucan", "Dextran 40", "Dextran 70", "Dextran 75", "dextran", "dextrane", "dextrano", "dextrans", "dextranum" ; oboInOwl:id "CHEBI:52071" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "dextran" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_53424 obo:IAO_0000115 "A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C58H114O26" ; chebi:mass "1226.75977" ; chebi:monoisotopicmass "1226.760" ; oboInOwl:hasDbXref "Beilstein:8973037", "CAS:9005-64-5", "KEGG:C11624", "KEGG:D05565", "Reaxys:8187252", "Reaxys:8973037", "Wikipedia:Polysorbate_20" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Polyoxyethylene (20) sorbitan monolaurate", "Polyoxyethylene sorbitan monolaurate", "Polysorbate", "Polysorbate 20", "Tween 20", "polisorbato", "polysorbate", "polysorbatum" ; oboInOwl:id "CHEBI:53424" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "polysorbate 20" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_53426 obo:IAO_0000115 "A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by an oleoyl group." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C64H124O26" ; chebi:mass "1308.83802" ; chebi:monoisotopicmass "1308.838" ; oboInOwl:hasAlternativeId "CHEBI:9785" ; oboInOwl:hasDbXref "Beilstein:8187125", "CAS:9005-65-6", "KEGG:C11625", "KEGG:D01067", "Reaxys:8187125", "Reaxys:8190601", "Reaxys:8898414", "Reaxys:9040798", "Wikipedia:Polysorbate_80" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Glycol (polysorbate 80)", "Polyethylene oxide sorbitan mono-oleate", "Polyoxyethylene (20) sorbitan monooleate", "Polyoxyethylene sorbitan monooleate", "Polyoxyethylene sorbitan oleate", "Polysorbate 80", "Tween 80", "polisorbato", "polysorbate", "polysorbatum" ; oboInOwl:id "CHEBI:53426" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "polysorbate 80" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_64220 obo:IAO_0000115 "An organic sodium salt that is the monosodium salt of glutamic acid." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C5H8NNaO4" ; chebi:inchi "InChI=1S/C5H9NO4.Na/c6-3(5(9)10)1-2-4(7)8;/h3H,1-2,6H2,(H,7,8)(H,9,10);/q;+1/p-1" ; chebi:inchikey "LPUQAYUQRXPFSQ-UHFFFAOYSA-M" ; chebi:mass "169.11110" ; chebi:monoisotopicmass "169.03510" ; chebi:smiles "[Na+].[NH3+]C(CCC([O-])=O)C([O-])=O" ; oboInOwl:hasDbXref "PMID:22293291", "Reaxys:17003240" ; oboInOwl:hasExactSynonym "sodium 2-azaniumylpentanedioate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "MSG", "sodium 2-ammoniopentanedioate", "sodium glutamate" ; oboInOwl:id "CHEBI:64220" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "monosodium glutamate" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_7507 obo:IAO_0000115 "A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "CAS:1404-04-2", "DrugBank:DB00994", "KEGG:C00384", "KEGG:D08260" ; oboInOwl:hasExactSynonym "Neomycin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:7507" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "neomycin" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_9546 obo:IAO_0000115 "An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent." ; obo:IAO_0000412 ; chebi:charge "0" ; chebi:formula "C9H9HgNaO2S", "C9H9HgO2S.Na" ; chebi:inchi "InChI=1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2" ; chebi:inchikey "RTKIYNMVFMVABJ-UHFFFAOYSA-L" ; chebi:mass "404.81233" ; chebi:monoisotopicmass "405.99274" ; chebi:smiles "[Na+].CC[Hg]Sc1ccccc1C([O-])=O" ; oboInOwl:hasDbXref "Beilstein:8169555", "CAS:54-64-8", "Gmelin:1677155", "KEGG:D00864", "PMID:18837732", "PMID:21616561", "PMID:21785120", "PMID:22015977", "PMID:22366633", "PMID:22658806", "PMID:22811707", "PMID:23145070", "PMID:23223227", "PMID:23282150", "PMID:23401210", "PMID:23554557", "PMID:23843785", "PMID:23949514", "PMID:23965928", "PMID:23992327", "PMID:25042713", "PPDB:3062", "Reaxys:8169555", "VSDB:3062" ; oboInOwl:hasExactSynonym "Thimerosal", "sodium [(2-carboxylatophenyl)sulfanyl](ethyl)mercurate(1-)", "sodium ethyl[2-(sulfanyl-kappaS)benzoato(2-)]mercurate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Merthiolate", "Thiomersal", "[(o-carboxyphenyl)thio]ethylmercury sodium salt", "ethyl(2-mercaptobenzoato-S)mercury sodium salt", "ethylmercurithiosalicylate sodium", "ethylmercurithiosalicylic acid sodium salt", "mercurothiolate", "o-(ethylmercurithio)benzoic acid sodium salt", "sodium ethylmercurithiosalicylate", "sodium merthiolate", "thiomersal", "thiomersalate", "thiomersalum", "tiomersal" ; oboInOwl:id "CHEBI:9546" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "thimerosal" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CL_0000000 obo:IAO_0000115 "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "CALOHA:TS-2035", "FBbt:00007002", "FMA:68646", "GO:0005623", "KUPO:0000002", "MESH:D002477", "VHOG:0001533", "WBbt:0004017", "XAO:0003012" ; oboInOwl:inSubset ; a owl:Class ; rdfs:comment "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ; rdfs:label "cell" ; rdfs:subClassOf obo:UBERON_0000061 . obo:CL_0000182 obo:IAO_0000115 "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000575", "CALOHA:TS-0454", "FMA:14515" ; oboInOwl:inSubset ; a owl:Class ; rdfs:comment "Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive." ; rdfs:label "hepatocyte" ; rdfs:subClassOf obo:CL_0000000 . obo:CL_0000219 obo:IAO_0000115 "A cell that moves by its own activities." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "motile cell" ; rdfs:subClassOf obo:CL_0000000 . obo:CL_0000232 obo:IAO_0000115 "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000424", "CALOHA:TS-0290", "FMA:81100" ; oboInOwl:hasExactSynonym "RBC", "red blood cell" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "erythrocyte" ; rdfs:subClassOf obo:CL_0000763 . obo:CL_0000234 obo:IAO_0000115 "Any cell capable of ingesting particulate matter via phagocytosis." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "BTO:0001044", "FMA:83806", "MESH:D010586" ; a owl:Class ; rdfs:label "phagocyte" ; rdfs:subClassOf obo:CL_0000219 . obo:CL_0000235 obo:IAO_0000115 "A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000801", "CALOHA:TS-0587", "FMA:63261", "FMA:83585", "MESH:D008264" ; oboInOwl:hasExactSynonym "histiocyte" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:comment "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid." ; rdfs:label "macrophage" ; rdfs:subClassOf obo:CL_0000234, obo:CL_0000766 . obo:CL_0000738 obo:IAO_0000115 "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000751", "CALOHA:TS-0549", "FMA:62852", "MESH:D007962", "NCIT:C12529" ; oboInOwl:hasExactSynonym "leucocyte", "white blood cell" ; oboInOwl:hasRelatedSynonym "immune cell" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "leukocyte" ; rdfs:subClassOf obo:CL_0000219, obo:CL_0000988 . obo:CL_0000763 obo:IAO_0000115 "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "BTO:0001441", "CALOHA:TS-0647", "MESH:D022423" ; a owl:Class ; rdfs:label "myeloid cell" ; rdfs:subClassOf obo:CL_0000988 . obo:CL_0000766 obo:IAO_0000115 "A cell of the monocyte, granulocyte, or mast cell lineage." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "myeloid leukocyte" ; rdfs:subClassOf obo:CL_0000738, obo:CL_0000763 . obo:CL_0000988 obo:IAO_0000115 "A cell of a hematopoietic lineage." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "BTO:0000574", "CALOHA:TS-2017", "FMA:70366", "FMA:83598" ; oboInOwl:hasExactSynonym "haematopoietic cell", "haemopoietic cell", "hemopoietic cell" ; a owl:Class ; rdfs:label "hematopoietic cell" ; rdfs:subClassOf obo:CL_0000000 . obo:DOID_0050117 obo:IAO_0000115 "A disease that is the consequence of the presence of pathogenic microbial agents, including pathogenic viruses, pathogenic bacteria, fungi, protozoa, multicellular parasites, and aberrant proteins known as prions." ; obo:IAO_0000412 ; obo:OBI_9991118 "infectious disease" ; oboInOwl:hasAlternativeId "DOID:10115", "DOID:11078", "DOID:1304", "DOID:1321", "DOID:2040", "DOID:2288", "DOID:3099", "DOID:4120", "DOID:4620", "DOID:5256", "DOID:945", "DOID:95", "DOID:9532", "DOID:9696" ; oboInOwl:hasDbXref "ICD9CM:079.0", "UMLS_CUI:C0001485" ; oboInOwl:hasExactSynonym "infectious disease"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0050117" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:comment "DO:wk" ; rdfs:label "disease by infectious agent" ; rdfs:subClassOf obo:DOID_4 . obo:DOID_0050615 obo:IAO_0000115 "An organ system cancer located_in the respiratory system that is characterized by uncontrolled cellular proliferation in the respiratory tract." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0050615" ; a owl:Class ; rdfs:label "respiratory system cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_1579 . obo:DOID_0050686 obo:IAO_0000115 "A cancer that is classified based on the organ it starts in." ; obo:IAO_0000412 ; oboInOwl:created_by "snadendla" ; oboInOwl:creation_date "2011-06-13T03:28:33Z" ; oboInOwl:hasDbXref "MESH:D009371" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0050686" ; a owl:Class ; rdfs:label "organ system cancer" ; rdfs:subClassOf obo:DOID_162 . obo:DOID_0050687 obo:IAO_0000115 "A cancer that is classified by the type of cell from which it is derived." ; obo:IAO_0000412 ; oboInOwl:created_by "snadendla" ; oboInOwl:creation_date "2011-06-13T03:28:50Z" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0050687" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "cell type cancer" ; rdfs:subClassOf obo:DOID_162 . obo:DOID_0050746 obo:IAO_0000115 "A B-cell lymphocytic neoplasm due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles." ; obo:IAO_0000412 ; oboInOwl:created_by "lschriml" ; oboInOwl:creation_date "2012-09-18T02:00:45Z" ; oboInOwl:hasDbXref "GARD:6969", "ICDO:9673/3", "MESH:D020522" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0050746" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "mantle cell lymphoma" ; rdfs:subClassOf obo:DOID_707 . obo:DOID_0060058 obo:IAO_0000115 "A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1033", "DOID:353" ; oboInOwl:hasDbXref "ICD10CM:C85.9", "ICDO:9590/3", "MESH:D008223", "NCI:C3208", "NCI:C7065", "SNOMEDCT_US_2023_03_01:118600007", "SNOMEDCT_US_2023_03_01:414628006", "UMLS_CUI:C0024299", "UMLS_CUI:C0598798" ; oboInOwl:hasExactSynonym "lymphoid cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0060058" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "lymphoma" ; rdfs:subClassOf obo:DOID_0060073, obo:DOID_2531 . obo:DOID_0060073 obo:IAO_0000115 "An immune system cancer that is located_in the lymphatic system and is characterized by uncontrolled cellular proliferation of lymphoid tissue." ; obo:IAO_0000412 ; oboInOwl:created_by "lschriml" ; oboInOwl:creation_date "2011-05-11T01:05:14Z" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0060073" ; a owl:Class ; rdfs:label "lymphatic system cancer" ; rdfs:subClassOf obo:DOID_0060083 . obo:DOID_0060083 obo:IAO_0000115 "An organ system cancer located_in the immune system that is characterized by uncontrolled cellular proliferation in organs of the immune system." ; obo:IAO_0000412 ; oboInOwl:created_by "lschriml" ; oboInOwl:creation_date "2011-06-08T01:11:18Z" ; oboInOwl:hasDbXref "ICDO:9392/3" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0060083" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "immune system cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_2914 . obo:DOID_0060097 obo:IAO_0000115 "An organ system benign neoplam that is located_in the thoracic cavity." ; obo:IAO_0000412 ; oboInOwl:created_by "lschriml" ; oboInOwl:creation_date "2011-07-15T01:55:57Z" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0060097" ; a owl:Class ; rdfs:label "thoracic benign neoplasm" ; rdfs:subClassOf obo:DOID_0060118, obo:DOID_14566 . obo:DOID_0060100 obo:IAO_0000115 "An organ system cancer located_in the muscular and skeletal organs and characterized by uncontrolled cellular proliferation of the musculoskeletal organs." ; obo:IAO_0000412 ; oboInOwl:created_by "lschriml" ; oboInOwl:creation_date "2011-07-15T02:30:51Z" ; oboInOwl:hasAlternativeId "DOID:0060124" ; oboInOwl:hasExactSynonym "skeletal system cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0060100" ; a owl:Class ; rdfs:label "musculoskeletal system cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_17 . obo:DOID_0060118 obo:IAO_0000115 "A disease of anatomical entity that is located_in the thoracic cavity." ; obo:IAO_0000412 ; oboInOwl:created_by "lschriml" ; oboInOwl:creation_date "2011-07-25T02:23:47Z" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0060118" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "thoracic disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_0060119 obo:IAO_0000115 "A gastrointestinal system cancer that is located_in the pharynx." ; obo:IAO_0000412 ; oboInOwl:created_by "lschriml" ; oboInOwl:creation_date "2011-07-27T01:26:34Z" ; oboInOwl:hasDbXref "MESH:D010610", "NCI:C3325", "SNOMEDCT_US_2023_03_01:126685009", "UMLS_CUI:C0031347" ; oboInOwl:hasExactSynonym "pharyngeal neoplasm"@en, "pharynx neoplasm"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "pharyngeal cancer"@en ; oboInOwl:id "DOID:0060119" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "pharynx cancer" ; rdfs:subClassOf obo:DOID_3119 . obo:DOID_0080355 obo:IAO_0000115 "A gastrointestinal system cancer that is located_in the hepatobiliary system." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0080355" ; a owl:Class ; rdfs:label "hepatobiliary system cancer"@en ; rdfs:subClassOf obo:DOID_3119 . obo:DOID_0081267 obo:IAO_0000115 "An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD11:4B24", "MESH:D006086", "OMIM:614395", "ORDO:39812" ; oboInOwl:hasExactSynonym "GvHD", "graft versus host disease" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:0081267" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "graft-versus-host disease"@en ; rdfs:subClassOf obo:DOID_2914 . obo:DOID_10154 obo:IAO_0000115 "An intestinal cancer that is located_in the small intestine." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "GARD:9385", "ICD10CM:C17", "ICD9CM:152.9", "NCI:C7523", "SNOMEDCT_US_2023_03_01:363509000", "UMLS_CUI:C0153425" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:10154" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "small intestine cancer" ; rdfs:subClassOf obo:DOID_10155 . obo:DOID_10155 obo:IAO_0000115 "A gastrointestinal system cancer that is located_in the intestine." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:C26.0", "ICD9CM:159.0", "MESH:D007414", "NCI:C4572", "SNOMEDCT_US_2023_03_01:93838000", "UMLS_CUI:C0346627" ; oboInOwl:hasExactSynonym "malignant intestinal tumors"@en, "malignant neoplasm of intestine"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:10155" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "intestinal cancer" ; rdfs:subClassOf obo:DOID_3119, obo:DOID_5295 . obo:DOID_10283 obo:IAO_0000115 "A male reproductive organ cancer that is located_in the prostate." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:514" ; oboInOwl:hasDbXref "ICD10CM:C61", "ICD9CM:185", "KEGG:05215", "MESH:D011471", "NCI:C3343", "NCI:C7378", "OMIM:176807", "OMIM:300147", "OMIM:300704", "OMIM:601518", "OMIM:602759", "OMIM:608656", "OMIM:608658", "OMIM:609299", "OMIM:609558", "OMIM:610321", "OMIM:610997", "OMIM:611100", "OMIM:611868", "OMIM:611928", "OMIM:611955", "OMIM:611958", "OMIM:611959", "ORDO:1331", "SNOMEDCT_US_2023_03_01:126906006", "SNOMEDCT_US_2023_03_01:93974005", "UMLS_CUI:C0033578", "UMLS_CUI:C0376358" ; oboInOwl:hasExactSynonym "NGP - new growth of prostate"@en, "hereditary prostate cancer"@en, "malignant tumor of the prostate"@en, "prostate cancer, familial"@en, "prostate neoplasm"@en, "prostatic cancer"@en, "prostatic neoplasm"@en, "tumor of the prostate"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:10283" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:comment """Xref MGI. OMIM mapping confirmed by DO. [SN].""" ; rdfs:label "prostate cancer" ; rdfs:subClassOf obo:DOID_3856 . obo:DOID_104 obo:IAO_0000115 "A disease by infectious agent that results_in infection, has_material_basis_in Bacteria." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:A49.9", "MESH:D001424", "NCI:C2890", "SNOMEDCT_US_2023_03_01:87628006", "UMLS_CUI:C0004623" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:104" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "bacterial infectious disease" ; rdfs:subClassOf obo:DOID_0050117 . obo:DOID_10534 obo:IAO_0000115 "A gastrointestinal system cancer that is located_in the stomach." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:10539", "DOID:10542", "DOID:10543", "DOID:4713" ; oboInOwl:hasDbXref "GARD:7704", "ICD10CM:C16", "ICD10CM:C16.2", "ICD10CM:C16.5", "ICD10CM:C16.6", "ICD9CM:151", "ICD9CM:151.4", "ICD9CM:151.5", "ICD9CM:151.6", "MESH:D013274", "NCI:C3387", "NCI:C9331", "OMIM:613659", "SNOMEDCT_US_2023_03_01:126824007", "SNOMEDCT_US_2023_03_01:269459004", "SNOMEDCT_US_2023_03_01:269460009", "SNOMEDCT_US_2023_03_01:93717002", "SNOMEDCT_US_2023_03_01:94074003", "UMLS_CUI:C0024623", "UMLS_CUI:C0038356", "UMLS_CUI:C0153421", "UMLS_CUI:C0153422", "UMLS_CUI:C0153423" ; oboInOwl:hasExactSynonym "gastric cancer"@en, "gastric neoplasm"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:10534" ; oboInOwl:inSubset , , , , , , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "stomach cancer" ; rdfs:subClassOf obo:DOID_3119 . obo:DOID_1100 obo:IAO_0000115 "A female reproductive system disease that is located_in the ovary." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "MESH:D010049", "NCI:C26841", "SNOMEDCT_US_2023_03_01:5552004", "UMLS_CUI:C0029928" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1100" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "ovarian disease" ; rdfs:subClassOf obo:DOID_229, obo:DOID_28 . obo:DOID_11054 obo:IAO_0000115 "An urinary system cancer that results_in malignant growth located_in the urinary bladder." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:5428" ; oboInOwl:hasDbXref "GARD:12210", "ICD10CM:C67", "ICD9CM:188", "KEGG:05219", "MESH:D001749", "NCI:C2901", "NCI:C9334", "OMIM:109800", "SNOMEDCT_US_2023_03_01:126885006", "SNOMEDCT_US_2023_03_01:363455001", "UMLS_CUI:C0005684", "UMLS_CUI:C0005695" ; oboInOwl:hasExactSynonym "bladder cancer"@en, "tumor of the bladder"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:11054" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "urinary bladder cancer" ; rdfs:subClassOf obo:DOID_3996 . obo:DOID_11076 obo:IAO_0000115 "A brucellosis that involves an infection caused by Brucella suis [NCBITaxon:29461] in swine and humans. The disease has_symptom fever, has_symptom chills, has_symptom malaise, has_symptom diaphoresis, has_symptom arthralgia, has_symptom myalgia, has_symptom headache, has_symptom anorexia, and has_symptom fatigue." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:11076" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "Brucella suis brucellosis" ; rdfs:subClassOf obo:DOID_11077 . obo:DOID_11077 obo:IAO_0000115 "A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The disease has_symptom fever, has_symptom sweat, has_symptom headache, has_symptom back pain, has_symptom physical weakness, has_symptom joint pain and has_symptom fatigue." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:0050060" ; oboInOwl:hasDbXref "GARD:5966", "ICD10CM:A23", "ICD9CM:023", "MESH:D002006", "NCI:C84602", "SNOMEDCT_US_2023_03_01:154296006", "UMLS_CUI:C0006309" ; oboInOwl:hasExactSynonym "Maltese fever"@en, "undulant fever"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "Bang's disease"@en, "Gibraltar fever"@en, "Malta fever"@en, "Mediterranean fever"@en ; oboInOwl:id "DOID:11077" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "brucellosis" ; rdfs:subClassOf obo:DOID_104 . obo:DOID_1115 obo:IAO_0000115 "A cell type cancer that has_material_basis_in abnormally proliferating cells derives from embryonic mesoderm." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:3936" ; oboInOwl:hasDbXref "ICD10CM:C49", "ICD9CM:171.9", "ICDO:8800/3", "SNOMEDCT_US_2023_03_01:93765001", "UMLS_CUI:C0153519" ; oboInOwl:hasExactSynonym "connective and soft tissue neoplasm"@en, "tumor of soft tissue and skeleton"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1115" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "sarcoma" ; rdfs:subClassOf obo:DOID_0050687 . obo:DOID_1192 obo:IAO_0000115 "A nervous system cancer that is located in the peripheral nervous system." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:3194" ; oboInOwl:hasDbXref "MESH:D010524", "MESH:D018317", "NCI:C3321", "NCI:C4972", "SNOMEDCT_US_2023_03_01:126980002", "SNOMEDCT_US_2023_03_01:189946005", "UMLS_CUI:C0031118", "UMLS_CUI:C0206727" ; oboInOwl:hasExactSynonym "neoplasm of peripheral nerve"@en, "nerve sheath neoplasm"@en, "tumor of PNS"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1192" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "peripheral nervous system neoplasm" ; rdfs:subClassOf obo:DOID_3093 . obo:DOID_11934 obo:IAO_0000115 "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "GARD:12425", "MESH:D006258", "NCI:C3077", "SNOMEDCT_US_2023_03_01:255055008", "UMLS_CUI:C0018671" ; oboInOwl:hasExactSynonym "head and neck neoplasm"@en, "head and neck tumours"@en, "head/neck neoplasm"@en, "tumor of head and neck"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:11934" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:label "head and neck cancer" ; rdfs:subClassOf obo:DOID_0050686 . obo:DOID_120 obo:IAO_0000115 "A reproductive organ cancer that is manifested in the female genitals. This includes organs such as the ovaries, fallopian tubes, uterus, cervix, vagina and vulva." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1244", "DOID:1281" ; oboInOwl:hasDbXref "ICD10CM:C57", "ICD9CM:184", "MESH:D005833", "NCI:C3053", "NCI:C4913", "SNOMEDCT_US_2023_03_01:126907002", "SNOMEDCT_US_2023_03_01:188207007", "UMLS_CUI:C0017416", "UMLS_CUI:C0153585", "UMLS_CUI:C0699889" ; oboInOwl:hasExactSynonym "female reproductive cancer"@en, "malignant Gynecologic tumor"@en, "malignant neoplasm of female genital organ"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:120" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "female reproductive organ cancer" ; rdfs:subClassOf obo:DOID_193, obo:DOID_229 . obo:DOID_1240 obo:IAO_0000115 "A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:9145" ; oboInOwl:hasDbXref "ICD10CM:C95.90", "ICD9CM:208", "ICDO:9800/3", "MESH:D007938", "NCI:C3161", "SNOMEDCT_US_2023_03_01:255049003", "UMLS_CUI:C0023418" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1240" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "leukemia" ; rdfs:subClassOf obo:DOID_2531 . obo:DOID_1319 obo:IAO_0000115 "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:2125", "DOID:2126", "DOID:3543", "DOID:6649", "DOID:911" ; oboInOwl:hasDbXref "ICD10CM:C71", "ICD9CM:191", "ICD9CM:239.6", "MESH:D001932", "NCI:C170814", "NCI:C2907", "NCI:C3568", "NCI:C5115", "NCI:C7710", "SNOMEDCT_US_2023_03_01:126952004", "SNOMEDCT_US_2023_03_01:428061005", "SNOMEDCT_US_2023_03_01:93727008", "UMLS_CUI:C0006118", "UMLS_CUI:C0153633", "UMLS_CUI:C0220624", "UMLS_CUI:C0750974", "UMLS_CUI:C0750979", "UMLS_CUI:C1334557" ; oboInOwl:hasExactSynonym "BT - Brain tumour"@en, "adult brain tumor"@en, "adult malignant brain neoplasm"@en, "brain neoplasm"@en, "brain neoplasm, adult"@en, "malignant brain tumour"@en, "malignant primary brain neoplasm"@en, "malignant primary brain tumor"@en, "malignant tumor of Brain"@en, "malignant tumor of adult brain"@en, "neoplasm of brain"@en, "primary brain neoplasm"@en, "primary brain tumor"@en, "primary malignant neoplasm of brain"@en, "tumor of the Brain"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1319" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:label "brain cancer" ; rdfs:subClassOf obo:DOID_3620 . obo:DOID_1324 obo:IAO_0000115 "A respiratory system cancer that is located_in the lung." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:13075", "DOID:1322", "DOID:9881" ; oboInOwl:hasDbXref "ICD10CM:C34.1", "ICD10CM:C34.2", "ICD10CM:C34.3", "ICD9CM:162.3", "ICD9CM:162.4", "ICD9CM:162.5", "ICD9CM:162.8", "OMIM:211980", "OMIM:608935", "OMIM:612571", "OMIM:612593", "OMIM:614210", "SNOMEDCT_US_2023_03_01:187860004", "SNOMEDCT_US_2023_03_01:187864008", "SNOMEDCT_US_2023_03_01:187868006", "SNOMEDCT_US_2023_03_01:187874006", "UMLS_CUI:C0024624", "UMLS_CUI:C0153491", "UMLS_CUI:C0153492", "UMLS_CUI:C0153493" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "lung neoplasm"@en ; oboInOwl:id "DOID:1324" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "lung cancer" ; rdfs:subClassOf obo:DOID_0050615 . obo:DOID_14067 obo:IAO_0000115 "A malaria described as a severe form of the disease caused by a parasite Plasmodium falciparum, which is marked by irrregular recurrence of paroxysms and prolonged or continuous fever." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:B50", "ICD9CM:084.0", "MESH:D016778", "NCI:C34798", "SNOMEDCT_US_2023_03_01:62676009", "UMLS_CUI:C0024535" ; oboInOwl:hasExactSynonym "Malaria fever, subtertian"@en, "falciparum malaria"@en, "malignant tertian fever"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:14067" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "Plasmodium falciparum malaria" ; rdfs:subClassOf obo:DOID_0050117 . obo:DOID_14456 obo:IAO_0000115 "A brucellosis that involves an infection caused by Brucella melitensis [NCBITaxon:29459] in cattle, goats, sheep and humans. The disease has_symptom fever, has_symptom malaise, has_symptom anorexia, has_symptom limb pain and has_symptom back pain." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:A23.0", "ICD9CM:023.0", "SNOMEDCT_US_2023_03_01:186305007", "UMLS_CUI:C0302362" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:14456" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "Brucella melitensis brucellosis" ; rdfs:subClassOf obo:DOID_11077 . obo:DOID_14457 obo:IAO_0000115 "A brucellosis that involves an infection caused by Brucella abortus [NCBITaxon:235] in cattle and humans. The disease has_symptom fever, has_symptom chills, has_symptom sweats, has_symptom weight loss, has_symptom malaise, has_symptom headaches, has_symptom myalgia, and has_symptom arthralgia." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:A23.1", "ICD9CM:023.1", "MESH:D002007", "SNOMEDCT_US_2023_03_01:427795000", "UMLS_CUI:C0302363" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:14457" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "Brucella abortus brucellosis" ; rdfs:subClassOf obo:DOID_11077 . obo:DOID_14566 obo:IAO_0000115 "A disease that is characterized by abnormally rapid cell division." ; obo:IAO_0000412 ; obo:OBI_9991118 "neoplasm" ; oboInOwl:hasAlternativeId "DOID:0000818" ; oboInOwl:hasExactSynonym "cell process disease"@en, "neoplasm"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:14566" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "disease of cellular proliferation" ; rdfs:subClassOf obo:DOID_4 . obo:DOID_15 obo:IAO_0000115 "A disease of anatomical entity that is located_in reproductive system organs." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:6309" ; oboInOwl:hasDbXref "NCI:C27613", "UMLS_CUI:C1335037" ; oboInOwl:hasExactSynonym "genital system disease"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:15" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "reproductive system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_1542 obo:IAO_0000115 "A head and neck cancer that has_material_basis_in epithelial cells and is located in the upper aerodigestive tract, including the lip, oral cavity (mouth), nasal cavity, paranasal sinuses, pharynx, and larynx." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "NCI:C6077", "UMLS_CUI:C1334927" ; oboInOwl:hasExactSynonym "carcinoma of the neck"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "carcinoma of neck"@en ; oboInOwl:id "DOID:1542" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "head and neck carcinoma" ; rdfs:subClassOf obo:DOID_11934, obo:DOID_305 . obo:DOID_1579 obo:IAO_0000115 "A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:3226" ; oboInOwl:hasDbXref "ICD10CM:J98", "ICD9CM:519", "SNOMEDCT_US_2023_03_01:155603009", "UMLS_CUI:C0029582" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1579" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "respiratory system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_1612 obo:IAO_0000115 "A thoracic cancer that originates in the mammary gland." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1648", "DOID:4241" ; oboInOwl:hasDbXref "ICD10CM:C50", "MESH:D001943", "NCI:C9335", "OMIM:114480", "SNOMEDCT_US_2023_03_01:254837009", "UMLS_CUI:C0006142" ; oboInOwl:hasExactSynonym "breast tumor"@en, "malignant neoplasm of breast"@en, "malignant tumor of the breast"@en, "mammary cancer"@en, "mammary tumor"@en, "primary breast cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "mammary neoplasm"@en ; oboInOwl:id "DOID:1612" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:comment """Xref MGI. OMIM mapping confirmed by DO. [SN].""" ; rdfs:label "breast cancer" ; rdfs:subClassOf obo:DOID_5093 . obo:DOID_162 obo:IAO_0000115 "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:C80.1", "ICD9CM:199", "ICDO:8000/3", "MESH:D009369", "NCI:C9305", "SNOMEDCT_US_2023_03_01:269513004", "UMLS_CUI:C0006826" ; oboInOwl:hasExactSynonym "malignant neoplasm"@en, "malignant tumor"@en, "primary cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:162" ; oboInOwl:inSubset , , , , , , ; a owl:Class ; rdfs:comment "Updating out dated UMLS CUI." ; rdfs:label "cancer" ; rdfs:subClassOf obo:DOID_14566 . obo:DOID_17 obo:IAO_0000115 "A disease of anatomical entity that occurs in the muscular and/or skeletal system." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "MESH:D009140", "NCI:C107377", "SNOMEDCT_US_2023_03_01:268047003", "UMLS_CUI:C0026857" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:17" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "musculoskeletal system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_170 obo:IAO_0000115 "An organ system cancer located_in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:10009" ; oboInOwl:hasDbXref "ICD10CM:C75.9", "ICD9CM:194.9", "MESH:D004701", "NCI:C3010", "NCI:C3575", "SNOMEDCT_US_2023_03_01:127015005", "SNOMEDCT_US_2023_03_01:93780007", "UMLS_CUI:C0014132", "UMLS_CUI:C0153658" ; oboInOwl:hasExactSynonym "Endocrine tumor"@en, "endocrine neoplasm"@en, "malignant Endocrine tumor"@en, "malignant neoplasm of endocrine gland"@en, "malignant tumour of endocrine gland"@en, "neoplasm of endocrine gland"@en, "neoplasm of endocrine system"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:170" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "endocrine gland cancer" ; rdfs:subClassOf obo:DOID_0050686 . obo:DOID_1789 obo:IAO_0000412 ; oboInOwl:hasDbXref "NCI:C7633", "UMLS_CUI:C1377610" ; oboInOwl:hasExactSynonym "Mesothelioma of Peritoneum"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1789" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "benign peritoneal mesothelioma" ; rdfs:subClassOf obo:DOID_0060097 . obo:DOID_1793 obo:IAO_0000115 "An endocrine gland cancer located_in the pancreas." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:14356", "DOID:1797", "DOID:3588", "DOID:9859" ; oboInOwl:hasDbXref "GARD:9364", "ICD10CM:C25.0", "ICD10CM:C25.1", "ICD10CM:C25.2", "ICD9CM:157.0", "ICD9CM:157.1", "ICD9CM:157.2", "ICD9CM:157.8", "KEGG:05212", "MESH:D010190", "NCI:C3305", "ORDO:1333", "ORDO:217074", "SNOMEDCT_US_2023_03_01:126859007", "SNOMEDCT_US_2023_03_01:187796007", "SNOMEDCT_US_2023_03_01:93715005", "SNOMEDCT_US_2023_03_01:93823001", "SNOMEDCT_US_2023_03_01:94082003", "UMLS_CUI:C0030297", "UMLS_CUI:C0153458", "UMLS_CUI:C0153459", "UMLS_CUI:C0153460", "UMLS_CUI:C0153463" ; oboInOwl:hasExactSynonym "Ca body of pancreas"@en, "Ca head of pancreas"@en, "Ca tail of pancreas"@en, "malignant neoplasm of body of pancreas"@en, "malignant neoplasm of head of pancreas"@en, "malignant neoplasm of tail of pancreas"@en, "pancreas neoplasm"@en, "pancreatic neoplasm"@en, "pancreatic tumor"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1793" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:comment "Xref MGI." ; rdfs:label "pancreatic cancer" ; rdfs:subClassOf obo:DOID_170, obo:DOID_28 . obo:DOID_18 obo:IAO_0000115 "A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:579" ; oboInOwl:hasDbXref "NCI:C27599", "UMLS_CUI:C1335051" ; oboInOwl:hasExactSynonym "Non-neoplastic urinary tract disease"@en, "urinary tract disease"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:18" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "urinary system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_184 obo:IAO_0000115 "A connective tissue cancer that is located_in bone and is characterized by uncontrolled cellular proliferation that destroys normal bone tissue." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:3348" ; oboInOwl:hasDbXref "MESH:D001859", "NCI:C9343", "SNOMEDCT_US_2023_03_01:126537000", "UMLS_CUI:C0005967" ; oboInOwl:hasExactSynonym "CA - bone cancer"@en, "bone neoplasm"@en, "bone tumour"@en, "malignant bone neoplasm"@en, "malignant bone tumour"@en, "malignant neoplasm of bone"@en, "malignant osseous tumor"@en, "neoplasm of bone"@en, "osseous tumor"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:184" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "bone cancer" ; rdfs:subClassOf obo:DOID_201 . obo:DOID_1909 obo:IAO_0000115 "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from melanocytes which are found in skin, the bowel and the eye." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EFO:0000756", "ICDO:8720/3", "KEGG:05218", "MESH:D008545", "NCI:C3224", "SNOMEDCT_US_2023_03_01:2092003", "UMLS_CUI:C0025202" ; oboInOwl:hasExactSynonym "Naevocarcinoma"@en, "malignant melanoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1909" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "melanoma" ; rdfs:subClassOf obo:DOID_0050687 ; skos:exactMatch "MESH:D008545" . obo:DOID_193 obo:IAO_0000115 "An organ system cancer that is manifested in the reproductive organs." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1900" ; oboInOwl:hasDbXref "NCI:C3674", "UMLS_CUI:C0178830" ; oboInOwl:hasExactSynonym "Reproductive tumor"@en, "malignant reproductive system neoplasm"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "cancer of reproductive system"@en ; oboInOwl:id "DOID:193" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "reproductive organ cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_15 . obo:DOID_1964 obo:IAO_0000115 "A female reproductive organ cancer that is located_in fallopian tube." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1961" ; oboInOwl:hasDbXref "GARD:9162", "ICD10CM:C57.0", "ICD9CM:183.2", "MESH:D005185", "NCI:C3032", "NCI:C7480", "SNOMEDCT_US_2023_03_01:126916003", "SNOMEDCT_US_2023_03_01:93794008", "UMLS_CUI:C0015558", "UMLS_CUI:C0153579" ; oboInOwl:hasExactSynonym "fallopian tube neoplasm"@en, "malignant neoplasm of uterine tube"@en, "malignant tumor of fallopian tube"@en, "malignant tumour of fallopian tube"@en, "neoplasm of fallopian tube"@en, "tumor of the fallopian tube"@en, "tumor, fallopian tube, malignant"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:1964" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "fallopian tube cancer" ; rdfs:subClassOf obo:DOID_120 . obo:DOID_1993 obo:IAO_0000115 "A colorectal cancer that is located_in the rectum." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1989" ; oboInOwl:hasDbXref "ICD10CM:C20", "ICD9CM:154.1", "MESH:D012004", "NCI:C7418", "NCI:C9382", "SNOMEDCT_US_2023_03_01:254582000", "SNOMEDCT_US_2023_03_01:93984006", "UMLS_CUI:C0007113", "UMLS_CUI:C0949022" ; oboInOwl:hasExactSynonym "carcinoma of rectum"@en, "carcinoma of the rectum"@en, "malignant Rectal tumor"@en, "malignant neoplasm of rectum"@en, "malignant rectum tumor"@en, "malignant tumor of rectum"@en, "rectal cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "cancer of rectum"@en ; oboInOwl:id "DOID:1993" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "rectum cancer" ; rdfs:subClassOf obo:DOID_9256 . obo:DOID_201 obo:IAO_0000115 "A musculoskeletal system cancer that is located_in connective tissue." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "MESH:D009372", "SNOMEDCT_US_2023_03_01:126598008", "UMLS_CUI:C0027656" ; oboInOwl:hasExactSynonym "Tumour of connective tissue"@en, "connective tissue neoplasm"@en, "mesenchymal tissue malignant neoplasm", "neoplasm of connective tissues"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:201" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "connective tissue cancer" ; rdfs:subClassOf obo:DOID_0060100, obo:DOID_65 . obo:DOID_219 obo:IAO_0000115 "A colorectal cancer that is located_in the colon." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:C18", "ICD9CM:153", "MESH:D003110", "NCI:C9242", "SNOMEDCT_US_2023_03_01:363406005", "UMLS_CUI:C0007102" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:219" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "colon cancer" ; rdfs:subClassOf obo:DOID_9256 . obo:DOID_229 obo:IAO_0000115 "A reproductive system disease that impairs the ability to reproduce and is located in the uterus, vagina, cervix, ovaries or fallopian tubes." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD9CM:629.9", "MESH:D005831", "SNOMEDCT_US_2023_03_01:38233001", "UMLS_CUI:C0017411" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:229" ; a owl:Class ; rdfs:label "female reproductive system disease" ; rdfs:subClassOf obo:DOID_15 . obo:DOID_2394 obo:IAO_0000115 "A female reproductive organ cancer that is located_in the ovary." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:0060070", "DOID:2144", "DOID:9595" ; oboInOwl:hasDbXref "GARD:7295", "ICD10CM:C56", "ICD9CM:183.0", "MESH:D010051", "NCI:C4984", "NCI:C7431", "OMIM:167000", "OMIM:607893", "ORDO:213500", "ORDO:213517", "SNOMEDCT_US_2023_03_01:123843001", "SNOMEDCT_US_2023_03_01:372117006", "SNOMEDCT_US_2023_03_01:93934004", "UMLS_CUI:C0919267", "UMLS_CUI:C1140680", "UMLS_CUI:C1299247" ; oboInOwl:hasExactSynonym "malignant Ovarian tumor"@en, "malignant tumour of ovary"@en, "ovarian neoplasm"@en, "ovary neoplasm"@en, "primary ovarian cancer"@en, "tumor of the Ovary"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:2394" ; oboInOwl:inSubset , , , , , , ; a owl:Class ; rdfs:comment """Xref MGI. OMIM mapping confirmed by DO. [SN].""" ; rdfs:label "ovarian cancer" ; rdfs:subClassOf obo:DOID_1100, obo:DOID_120 . obo:DOID_2531 obo:IAO_0000115 "An organ system cancer located in the hematological system that is characterized by uncontrolled cellular proliferation in blood, bone marrow and lymph nodes." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1034", "DOID:2532" ; oboInOwl:hasDbXref "MESH:D019337", "NCI:C27134", "SNOMEDCT_US_2023_03_01:414388001", "UMLS_CUI:C0376544" ; oboInOwl:hasExactSynonym "Hematologic malignancy"@en, "Hematologic neoplasm"@en, "Hematological tumors"@en, "blood cancer"@en, "hematopoietic and lymphoid system tumor"@en, "hematopoietic cancer"@en, "hematopoietic neoplasm"@en, "hematopoietic tumors"@en, "malignant hematopoietic neoplasm"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:2531" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:label "hematologic cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_74 . obo:DOID_263 obo:IAO_0000115 "A urinary system cancer that is located_in the kidney." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:11834", "DOID:3676" ; oboInOwl:hasDbXref "ICD10CM:C64", "ICD9CM:189.0", "MESH:D007680", "NCI:C120456", "NCI:C3150", "NCI:C7548", "SNOMEDCT_US_2023_03_01:126880001", "SNOMEDCT_US_2023_03_01:93849006", "UMLS_CUI:C0022665", "UMLS_CUI:C0494158", "UMLS_CUI:C0740457" ; oboInOwl:hasExactSynonym "malignant neoplasm of kidney except pelvis"@en, "malignant tumour of kidney"@en, "renal cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:263" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "kidney cancer" ; rdfs:subClassOf obo:DOID_3996 . obo:DOID_28 obo:IAO_0000115 "A disease of anatomical entity that is located_in endocrine glands which secretes a type of hormone directly into the bloodstream to regulate the body." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:E34.9", "ICD9CM:259.9", "MESH:D004700", "NCI:C3009", "SNOMEDCT_US_2023_03_01:67432001", "UMLS_CUI:C0014130" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:28" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:label "endocrine system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_2914 obo:IAO_0000115 "A disease of anatomical entity that is located_in the immune system." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EFO:0000540", "ICD10CM:D89.9", "ICD9CM:279.9", "SNOMEDCT_US_2023_03_01:154782004", "UMLS_CUI:C0041806" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:2914" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "immune system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_299 obo:IAO_0000115 "A carcinoma that has_material_basis_in abnormally proliferating cells, derives_from epithelial cells, which originate in glandular tissue." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICDO:8140/3", "MESH:D000230", "NCI:C2852", "SNOMEDCT_US_2023_03_01:35917007", "UMLS_CUI:C0001418" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:299" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "adenocarcinoma" ; rdfs:subClassOf obo:DOID_305 ; skos:exactMatch "MESH:D000230" . obo:DOID_305 obo:IAO_0000115 "A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:2428", "DOID:6570" ; oboInOwl:hasDbXref "ICDO:8010/3", "MESH:D002277", "MESH:D009375", "NCI:C2916", "NCI:C3709", "SNOMEDCT_US_2023_03_01:188083002", "SNOMEDCT_US_2023_03_01:269513004", "SNOMEDCT_US_2023_03_01:71298006", "UMLS_CUI:C0007097", "UMLS_CUI:C0553707", "UMLS_CUI:C1368683" ; oboInOwl:hasExactSynonym "epithelial cancer"@en, "epithelioma"@en, "malignant Epithelioma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:305" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "carcinoma" ; rdfs:subClassOf obo:DOID_0050687 . obo:DOID_3068 obo:IAO_0000115 "A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:3075", "DOID:3080" ; oboInOwl:hasDbXref "GARD:2491", "ICDO:9440/3", "MESH:D005909", "NCI:C129295", "NCI:C39750", "NCI:C9094", "SNOMEDCT_US_2023_03_01:63634009", "UMLS_CUI:C0017636", "UMLS_CUI:C0278878", "UMLS_CUI:C1514422" ; oboInOwl:hasExactSynonym "GBM"@en, "adult glioblastoma multiforme"@en, "glioblastoma multiforme", "grade IV adult Astrocytic tumor"@en, "primary glioblastoma multiforme"@en, "spongioblastoma multiforme"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3068" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "glioblastoma" ; rdfs:subClassOf obo:DOID_3069 . obo:DOID_3069 obo:IAO_0000115 "A malignant glioma that is has_material_basis_in astrocyte cells, a type of star-shaped glial cell, located in the brain and spinal cord." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:4861" ; oboInOwl:hasDbXref "ICDO:9400/3", "MESH:D001254", "NCI:C4951", "NCI:C60781", "SNOMEDCT_US_2023_03_01:189914005", "SNOMEDCT_US_2023_03_01:99131000119108", "UMLS_CUI:C0004114", "UMLS_CUI:C0750935" ; oboInOwl:hasExactSynonym "Astrocytic tumor"@en, "astrocytoma of Cerebrum"@en, "astrocytoma of brain"@en, "astroglioma"@en, "cerebral astrocytoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3069" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "malignant astrocytoma" ; rdfs:subClassOf obo:DOID_0050687, obo:DOID_3620 ; skos:exactMatch "MESH:D001254" . obo:DOID_3093 obo:IAO_0000115 "An organ system cancer located_in the nervous system that affects the central or peripheral nervous system." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1193", "DOID:3195", "DOID:4695" ; oboInOwl:hasDbXref "ICD9CM:192.9", "MESH:D009380", "NCI:C35562", "SNOMEDCT_US_2023_03_01:188306000", "UMLS_CUI:C0027665", "UMLS_CUI:C0153643", "UMLS_CUI:C1334956" ; oboInOwl:hasExactSynonym "malignant neoplasm of nervous system"@en, "neoplasm of nervous system"@en, "nervous system neoplasm"@en, "neural neoplasm"@en, "neural tumor"@en, "tumor of the nervous system"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3093" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "nervous system cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_863 . obo:DOID_3118 obo:IAO_0000115 "A gastrointestinal system disease that is located_in the liver and/or biliary tract." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "MESH:D004066", "NCI:C3959", "UMLS_CUI:C0267792" ; oboInOwl:hasExactSynonym "liver and biliary tract disease"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3118" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "hepatobiliary disease" ; rdfs:subClassOf obo:DOID_77 . obo:DOID_3119 obo:IAO_0000115 "An organ system cancer located_in gastrointestinal tract that is manifested in organs of the gastrointestinal system." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:4945", "DOID:8377" ; oboInOwl:hasDbXref "ICD10CM:C26.9", "ICD9CM:239.0", "MESH:D004067", "MESH:D005770", "NCI:C3052", "NCI:C4890", "SNOMEDCT_US_2023_03_01:128348002", "SNOMEDCT_US_2023_03_01:276806006", "SNOMEDCT_US_2023_03_01:428905002", "UMLS_CUI:C0012243", "UMLS_CUI:C0017185", "UMLS_CUI:C0685938" ; oboInOwl:hasExactSynonym "GI tumor"@en, "digestive system cancer"@en, "gastrointestinal tract cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3119" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "gastrointestinal system cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_77 . obo:DOID_3347 obo:IAO_0000115 "A bone sarcoma that is located_in bone that has_material_basis_in cells of mesenchymal origin." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:183" ; oboInOwl:hasDbXref "GARD:7284", "ICDO:9180/3", "MESH:D012516", "MESH:D018213", "NCI:C9145", "OMIM:259500", "ORDO:668", "SNOMEDCT_US_2023_03_01:189878003", "UMLS_CUI:C0029463", "UMLS_CUI:C0206639" ; oboInOwl:hasExactSynonym "Osteogenic sarcoma"@en, "Skeletal sarcoma"@en, "bone tissue neoplasm"@en, "osteoid sarcoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3347" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "osteosarcoma" ; rdfs:subClassOf obo:DOID_184 . obo:DOID_3369 obo:IAO_0000115 "A connective tissue cancer that has_material_basis_in neural crest cells derives_from undeveloped, undifferentiated neuroectoderm." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:0050607", "DOID:4158", "DOID:4390", "DOID:4391", "DOID:4392", "DOID:4980" ; oboInOwl:hasDbXref "GARD:6390", "ICDO:9364/3", "MESH:C563168", "MESH:D012512", "MESH:D018241", "NCI:C27901", "NCI:C27903", "NCI:C4817", "NCI:C7542", "NCI:C7806", "NCI:C9341", "OMIM:612219", "SNOMEDCT_US_2023_03_01:134210007", "SNOMEDCT_US_2023_03_01:73676002", "SNOMEDCT_US_2023_03_01:76909002", "UMLS_CUI:C0553580", "UMLS_CUI:C0684337", "UMLS_CUI:C0796547", "UMLS_CUI:C0863029", "UMLS_CUI:C0877849", "UMLS_CUI:C1334408" ; oboInOwl:hasExactSynonym "Ewing's family localized tumor"@en, "Ewing's sarcoma/peripheral primitive neuroectodermal tumor"@en, "Ewing's tumor"@en, "Ewings sarcoma"@en, "Ewings sarcoma-primitive neuroectodermal tumor"@en, "PNET of Thoracopulmonary Region"@en, "localized Ewing sarcoma"@en, "localized Ewing's sarcoma"@en, "localized Ewing's sarcoma/peripheral primitive neuroectodermal tumor"@en, "localized Ewing's tumor"@en, "localized peripheral primitive neuroectodermal tumor"@en, "peripheral primitive neuroectodermal tumor"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3369" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "Ewing sarcoma" ; rdfs:subClassOf obo:DOID_201 . obo:DOID_345 obo:IAO_0000115 "A female reproductive system disease that is located_in the uterus." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:N85.9", "ICD9CM:621.9", "MESH:D014591", "NCI:C26907", "SNOMEDCT_US_2023_03_01:237068005", "UMLS_CUI:C0042131" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:345" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "uterine disease" ; rdfs:subClassOf obo:DOID_229 . obo:DOID_3571 obo:IAO_0000115 "A hepatobiliary system cancer that is located_in the liver." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:12300", "DOID:269", "DOID:7330", "DOID:915", "DOID:919" ; oboInOwl:hasDbXref "ICD10CM:C22.0", "ICD10CM:C22.9", "ICD9CM:155.0", "ICD9CM:155.2", "MESH:D008113", "NCI:C34803", "NCI:C7692", "SNOMEDCT_US_2023_03_01:126851005", "SNOMEDCT_US_2023_03_01:187771009", "SNOMEDCT_US_2023_03_01:93870000", "UMLS_CUI:C0023903", "UMLS_CUI:C0024620", "UMLS_CUI:C0345904", "UMLS_CUI:C0854795" ; oboInOwl:hasExactSynonym "Ca liver - primary"@en, "Resectable malignant neoplasm of Liver"@en, "hepatic cancer"@en, "hepatic neoplasm"@en, "malignant hepato-biliary neoplasm"@en, "malignant neoplasm of liver"@en, "malignant neoplasm of liver, not specified as primary or secondary"@en, "malignant neoplasm of liver, primary"@en, "malignant tumor of liver"@en, "neoplasm of liver"@en, "non-resectable primary hepatic malignant neoplasm"@en, "primary liver cancer"@en, "primary malignant neoplasm of liver"@en, "resectable malignant neoplasm of the liver"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3571" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "liver cancer" ; rdfs:subClassOf obo:DOID_0080355, obo:DOID_170, obo:DOID_3118 . obo:DOID_3620 obo:IAO_0000115 "A nervous system cancer that is located_in the central nervous system." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:0060093", "DOID:1318" ; oboInOwl:hasDbXref "EFO:0000326", "ICD10CM:C72.9", "MESH:D016543", "NCI:C4627", "NCI:C9293", "SNOMEDCT_US_2023_03_01:126951006", "SNOMEDCT_US_2023_03_01:93744007", "UMLS_CUI:C0085136", "UMLS_CUI:C0348374" ; oboInOwl:hasExactSynonym "CNS neoplasm"@en, "central nervous system tumor"@en, "central nervous system tumors"@en, "malignant neoplasm of central nervous system"@en, "malignant tumor of CNS"@en, "neoplasm of central nervous system"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3620" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "central nervous system cancer" ; rdfs:subClassOf obo:DOID_3093 . obo:DOID_363 obo:IAO_0000115 "A female reproductive organ cancer that is located_in the uterus." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:4363" ; oboInOwl:hasDbXref "ICD10CM:C55", "ICD9CM:179", "MESH:D014594", "NCI:C3435", "NCI:C3552", "SNOMEDCT_US_2023_03_01:126908007", "SNOMEDCT_US_2023_03_01:371973000", "UMLS_CUI:C0042138", "UMLS_CUI:C0153567" ; oboInOwl:hasExactSynonym "CA - cancer of uterus"@en, "Tumour of uterus"@en, "malignant neoplasm of uterus"@en, "malignant uterine tumor"@en, "neoplasm of uterus"@en, "uterine tumor"@en, "uterus neoplasm"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:363" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "uterine cancer" ; rdfs:subClassOf obo:DOID_120, obo:DOID_345 . obo:DOID_3717 obo:IAO_0000115 "A stomach carcinoma that derives_from epithelial cells of glandular origin." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "NCI:C4004", "SNOMEDCT_US_2023_03_01:408647009", "UMLS_CUI:C0278701" ; oboInOwl:hasExactSynonym "adenocarcinoma of stomach"@en, "stomach adenocarcinoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3717" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "gastric adenocarcinoma" ; rdfs:subClassOf obo:DOID_299, obo:DOID_5517 . obo:DOID_3856 obo:IAO_0000115 "A reproductive organ cancer that is manifested in the male genital system. This includes organs such as the penis and scrotum." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:10284" ; oboInOwl:hasDbXref "ICD10CM:C63.9", "ICD9CM:187.9", "MESH:D005834", "NCI:C3054", "NCI:C8561", "SNOMEDCT_US_2023_03_01:126895004", "SNOMEDCT_US_2023_03_01:363515000", "UMLS_CUI:C0017417", "UMLS_CUI:C0153606" ; oboInOwl:hasExactSynonym "male genital cancer"@en, "male reproductive system neoplasm"@en, "malignant neoplasm of male genital organ"@en, "malignant neoplasm of male genital organ or tract"@en, "malignant neoplasm of male genital organs"@en, "malignant tumor of male Reproductive system"@en, "malignant tumor of male genital organ"@en, "neoplasm of male genital organ"@en, "tumor of male Reproductive system"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "male genital neoplasm"@en ; oboInOwl:id "DOID:3856" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "male reproductive organ cancer" ; rdfs:subClassOf obo:DOID_193 . obo:DOID_3905 obo:IAO_0000115 "A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EFO:0001071", "NCI:C4878", "SNOMEDCT_US_2023_03_01:154485001", "UMLS_CUI:C0684249" ; oboInOwl:hasExactSynonym "cancer of lung"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "carcinoma of lung"@en ; oboInOwl:id "DOID:3905" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "lung carcinoma" ; rdfs:subClassOf obo:DOID_1324, obo:DOID_305 . obo:DOID_3908 obo:IAO_0000115 "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EFO:0003060", "KEGG:05223", "MESH:D002289", "NCI:C2926", "SNOMEDCT_US_2023_03_01:254637007", "UMLS_CUI:C0007131" ; oboInOwl:hasExactSynonym "NSCLC"@en, "Non-small cell lung cancer"@en, "non-small cell lung carcinoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3908" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "lung non-small cell carcinoma" ; rdfs:subClassOf obo:DOID_3905 . obo:DOID_3996 obo:IAO_0000115 "An organ system cancer that is located_in the kidneys, ureteres, bladder or urethra." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:C68.9", "ICD9CM:189.9", "SNOMEDCT_US_2023_03_01:448233000", "UMLS_CUI:C0348371" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:3996" ; a owl:Class ; rdfs:label "urinary system cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_18 . obo:DOID_4 obo:IAO_0000115 "A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "MESH:D004194", "NCI:C2991", "SNOMEDCT_US_2023_03_01:64572001", "UMLS_CUI:C0012634" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:4" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "disease" ; rdfs:subClassOf obo:BFO_0000016 . obo:DOID_4362 obo:IAO_0000115 "A female reproductive organ cancer that is located_in the cervix." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:4361" ; oboInOwl:hasDbXref "ICD10CM:C53", "ICD9CM:180", "MESH:D002583", "NCI:C2940", "NCI:C9311", "OMIM:603956", "SNOMEDCT_US_2023_03_01:123841004", "SNOMEDCT_US_2023_03_01:254885005", "UMLS_CUI:C0007847", "UMLS_CUI:C0007873" ; oboInOwl:hasExactSynonym "cervical neoplasm"@en, "cervix cancer"@en, "cervix uteri cancer"@en, "neoplasm of uterine cervix"@en, "tumor of the Cervix Uteri"@en, "uterine cervical neoplasm"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:4362" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "cervical cancer" ; rdfs:subClassOf obo:DOID_363 . obo:DOID_4606 obo:IAO_0000115 "A biliary tract cancer that is located_in the bile duct." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:10019" ; oboInOwl:hasDbXref "ICD10CM:C24.0", "ICD9CM:156.1", "MESH:D001650", "NCI:C2898", "NCI:C7483", "SNOMEDCT_US_2023_03_01:93790004", "UMLS_CUI:C0005396", "UMLS_CUI:C0153453" ; oboInOwl:hasExactSynonym "Ca extrahepatic bile ducts"@en, "bile duct tumor"@en, "malignant neoplasm of the extrahepatic bile duct"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:4606" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "bile duct cancer" ; rdfs:subClassOf obo:DOID_0080355, obo:DOID_3118 . obo:DOID_4896 obo:IAO_0000115 "A bile duct carcinoma that derives_from epithelial cells of glandular origin." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "NCI:C27813", "SNOMEDCT_US_2023_03_01:70179006", "UMLS_CUI:C1370800" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:4896" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "bile duct adenocarcinoma" ; rdfs:subClassOf obo:DOID_299, obo:DOID_4897 . obo:DOID_4897 obo:IAO_0000115 "A bile duct cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "MESH:D001650", "NCI:C27814", "SNOMEDCT_US_2023_03_01:70179006", "UMLS_CUI:C0740277" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:4897" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "bile duct carcinoma" ; rdfs:subClassOf obo:DOID_305, obo:DOID_4606 . obo:DOID_4947 obo:IAO_0000115 "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:5249" ; oboInOwl:hasDbXref "ICD10CM:C22.1", "ICDO:8160/3", "MESH:D018281", "NCI:C4436", "NCI:C8265", "SNOMEDCT_US_2023_03_01:70179006", "UMLS_CUI:C0206698", "UMLS_CUI:C0280725" ; oboInOwl:hasExactSynonym "adult primary Cholangiocarcinoma"@en, "adult primary cholangiocellular carcinoma"@en, "cholangiosarcoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:4947" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "cholangiocarcinoma" ; rdfs:subClassOf obo:DOID_4896 . obo:DOID_4960 obo:IAO_0000115 "A hematopoietic cancer that derives_from the blood-forming stem cells of the bone marrow." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:2356", "DOID:2761" ; oboInOwl:hasDbXref "EFO:0004251", "ICD10CM:D47.1", "MESH:D009196", "SNOMEDCT_US_2023_03_01:128925001", "UMLS_CUI:C0027022" ; oboInOwl:hasExactSynonym "bone Marrow tumor"@en, "bone marrow neoplasm"@en, "malignant bone Marrow tumor"@en, "malignant neoplasm of bone marrow"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:4960" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "bone marrow cancer" ; rdfs:subClassOf obo:DOID_2531 . obo:DOID_5041 obo:IAO_0000115 "A gastrointestinal system cancer that is located_in the esophagus." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:10291", "DOID:10292", "DOID:10448", "DOID:1102", "DOID:1104" ; oboInOwl:hasDbXref "GARD:6383", "ICD10CM:C15.3", "ICD10CM:C15.4", "ICD10CM:C15.5", "ICD9CM:150.2", "ICD9CM:150.3", "ICD9CM:150.4", "ICD9CM:150.5", "ICD9CM:150.8", "MESH:D004938", "NCI:C3028", "NCI:C3533", "NCI:C3534", "NCI:C3535", "NCI:C4764", "OMIM:133239", "SNOMEDCT_US_2023_03_01:126817006", "SNOMEDCT_US_2023_03_01:187729008", "SNOMEDCT_US_2023_03_01:93656003", "SNOMEDCT_US_2023_03_01:93877002", "SNOMEDCT_US_2023_03_01:93895004", "SNOMEDCT_US_2023_03_01:94119000", "UMLS_CUI:C0014859", "UMLS_CUI:C0153413", "UMLS_CUI:C0153414", "UMLS_CUI:C0153415", "UMLS_CUI:C0153416", "UMLS_CUI:C0496775" ; oboInOwl:hasExactSynonym "Ca lower third oesophagus"@en, "Ca middle third oesophagus"@en, "esophagus cancer"@en, "malignant neoplasm of distal third of esophagus"@en, "malignant neoplasm of lower third of oesophagus"@en, "malignant neoplasm of middle third of oesophagus"@en, "malignant neoplasm of proximal third of esophagus"@en, "malignant neoplasm of upper third esophagus"@en, "malignant tumor of Distal Third of esophagus"@en, "malignant tumor of Proximal Third of esophagus"@en, "malignant tumor of abdominal esophagus"@en, "malignant tumor of the middle Third of the esophagus"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:5041" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:label "esophageal cancer" ; rdfs:subClassOf obo:DOID_3119 . obo:DOID_5093 obo:IAO_0000115 "An organ system cancer located_in the thoracic cavity that develops in the different types of cells within the lungs, as well as less common cancers of the esophagus, the trachea, or the chest wall." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:3937" ; oboInOwl:hasDbXref "ICD10CM:C76.1", "ICD9CM:195.1", "MESH:D013899", "NCI:C3406", "NCI:C3576", "SNOMEDCT_US_2023_03_01:188361007", "SNOMEDCT_US_2023_03_01:255058005", "UMLS_CUI:C0039981", "UMLS_CUI:C0153661" ; oboInOwl:hasExactSynonym "Thoracic tumor"@en, "thorax cancer"@en, "thorax neoplasm"@en, "tumor of thorax"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:5093" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "thoracic cancer" ; rdfs:subClassOf obo:DOID_0050686, obo:DOID_0060118 . obo:DOID_526 obo:IAO_0000115 "A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:B20", "ICD9CM:042-042.99", "MESH:D015658", "NCI:C3108", "SNOMEDCT_US_2023_03_01:86406008", "UMLS_CUI:C0019693" ; oboInOwl:hasExactSynonym "HIV infection"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:526" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "human immunodeficiency virus infectious disease" ; rdfs:subClassOf obo:DOID_934 . obo:DOID_5295 obo:IAO_0000115 "A gastrointestinal system disease that is located_in the intestine." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:10759", "DOID:11222", "DOID:11789", "DOID:8531", "DOID:8558", "DOID:8591" ; oboInOwl:hasDbXref "ICD10CM:K63.9", "ICD9CM:569.9", "MESH:D007410", "NCI:C26801", "SNOMEDCT_US_2023_03_01:266483008", "UMLS_CUI:C0021831" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:5295" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "intestinal disease" ; rdfs:subClassOf obo:DOID_77 . obo:DOID_5409 obo:IAO_0000115 "A lung carcinoma that has_material_basis_in primitive-appearing cells that are smaller than normal cells and is located_in the lung." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:0050875" ; oboInOwl:hasDbXref "KEGG:05222", "MESH:D055752", "NCI:C4917", "OMIM:182280", "SNOMEDCT_US_2023_03_01:254632001", "UMLS_CUI:C0149925" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:5409" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "lung small cell carcinoma" ; rdfs:subClassOf obo:DOID_3905 . obo:DOID_5517 obo:IAO_0000115 "A stomach cancer that is located_in the stomach." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EFO:0000178", "NCI:C4911", "SNOMEDCT_US_2023_03_01:154446008", "UMLS_CUI:C0699791" ; oboInOwl:hasExactSynonym "cancer of the stomach"@en, "carcinoma of stomach"@en, "gastric carcinoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:5517" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "stomach carcinoma" ; rdfs:subClassOf obo:DOID_10534, obo:DOID_305 . obo:DOID_5520 obo:IAO_0000115 "A head and neck carcinoma that has_material_basis_in squamous cells that line the moist, mucosal surfaces inside the head and neck." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "GARD:8503", "MESH:D000077195", "NCI:C34447", "OMIM:275355", "SNOMEDCT_US_2023_03_01:716659002", "UMLS_CUI:C1168401" ; oboInOwl:hasExactSynonym "carcinoma of the head and neck"@en, "squamous cell carcinoma of the head and neck"@en, "squamous cell carcinomas of head and neck"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:5520" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "head and neck squamous cell carcinoma" ; rdfs:subClassOf obo:DOID_1542 . obo:DOID_65 obo:IAO_0000115 "A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "MESH:D003240", "NCI:C26729", "SNOMEDCT_US_2023_03_01:201432001", "UMLS_CUI:C0009782" ; oboInOwl:hasExactSynonym "connective tissue disorder"@en, "disorder of connective tissue"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:65" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "connective tissue disease" ; rdfs:subClassOf obo:DOID_17 . obo:DOID_6536 obo:IAO_0000115 "A mature B-cell neoplasm that is composed of plasma cells." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EFO:0000200", "MESH:D010265", "SNOMEDCT_US_2023_03_01:71390001", "UMLS_CUI:C1136084" ; oboInOwl:hasExactSynonym "Plasma cell dyscrasia"@en, "Plasma cell tumour"@en, "Plasmacytic tumor"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:6536" ; a owl:Class ; rdfs:label "plasma cell neoplasm" ; rdfs:subClassOf obo:DOID_707 . obo:DOID_684 obo:IAO_0000115 "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:5005" ; oboInOwl:hasDbXref "EFO:0000182", "ICD10CM:C22.0", "ICDO:8170/3", "MESH:D006528", "NCI:C3099", "OMIM:114550", "ORDO:88673", "SNOMEDCT_US_2023_03_01:154469006", "UMLS_CUI:C2239176" ; oboInOwl:hasExactSynonym "Hepatoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:684" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "hepatocellular carcinoma" ; rdfs:subClassOf obo:DOID_686 . obo:DOID_686 obo:IAO_0000115 "A liver cancer that has_material_basis_in epithelial cells." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "NCI:C7927", "UMLS_CUI:C0279000" ; oboInOwl:hasExactSynonym "Liver and Intrahepatic bile duct carcinoma"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:686" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "liver carcinoma" ; rdfs:subClassOf obo:DOID_305, obo:DOID_3571 . obo:DOID_7 obo:IAO_0000115 "A disease that manifests in a defined anatomical structure." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1", "DOID:2", "DOID:5", "DOID:71", "DOID:72", "DOID:8" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:7" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "disease of anatomical entity" ; rdfs:subClassOf obo:DOID_4 . obo:DOID_707 obo:IAO_0000115 "A non-Hodgkin lymphoma that has_material_basis_in B cells." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "GARD:5877", "MESH:D016393", "NCI:C3457", "SNOMEDCT_US_2023_03_01:109979007", "UMLS_CUI:C0079731" ; oboInOwl:hasExactSynonym "B-cell lymphocytic neoplasm"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:707" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "B-cell lymphoma" ; rdfs:subClassOf obo:DOID_0060058 . obo:DOID_74 obo:IAO_0000115 "A disease of anatomical entity that has_material_basis_in hematopoietic cells." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:D75.9", "ICD9CM:289.9", "MESH:D006402", "NCI:C26323", "SNOMEDCT_US_2023_03_01:154785002", "UMLS_CUI:C0018939" ; oboInOwl:hasExactSynonym "Blood disease"@en, "Blood dyscrasia"@en, "DISEASE OF THE BLOOD AND BLOOD-FORMING ORGANS"@en, "Hematological disease"@en, "blood disorder"@en, "disease of haematopoietic system"@en, "disease of hematopoietic system"@en, "haematopoietic system disease"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:74" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "hematopoietic system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_769 obo:IAO_0000115 "An autonomic nervous system neoplasm that derives_from immature nerve cells." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EFO:0000621", "GARD:7185", "ICDO:9500/3", "MESH:D009447", "NCI:C3270", "ORDO:635", "SNOMEDCT_US_2023_03_01:432328008", "UMLS_CUI:C0027819" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:769" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:comment """Xref MGI. OMIM mapping confirmed by DO. [SN].""" ; rdfs:label "neuroblastoma" ; rdfs:subClassOf obo:DOID_1192 . obo:DOID_77 obo:IAO_0000115 "A disease of anatomical entity that is located_in the gastrointestinal tract." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:27", "DOID:944" ; oboInOwl:hasDbXref "ICD10CM:K92.9", "ICD9CM:520-579.99", "MESH:D004066", "SNOMEDCT_US_2023_03_01:53619000", "UMLS_CUI:C0012242" ; oboInOwl:hasExactSynonym "GIT disease"@en, "Gastroenteropathy"@en, "alimentary system disease"@en, "digestive system disorder"@en, "gastrointestinal disease"@en, "gastrointestinal disorder"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:77" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "gastrointestinal system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_8469 obo:IAO_0000115 "A viral infectious disease that results in infection, located in respiratory tract, has_material_basis_in Influenzavirus A, has_material_basis_in Influenzavirus B, or has_material_basis_in Influenzavirus C, which are transmitted_by droplet spread of oronasal secretions during coughing, sneezing, or talking from an infected person. It is a highly contagious disease that affects birds and mammals and has_symptom chills, has_symptom fever, has_symptom sore throat, has_symptom runny nose, has_symptom muscle pains, has_symptom severe headache, has_symptom cough, and has_symptom weakness." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:8468" ; oboInOwl:hasDbXref "ICD10CM:J11.1", "ICD9CM:487", "MESH:D007251", "NCI:C53482", "SNOMEDCT_US_2023_03_01:155559006", "UMLS_CUI:C0021400" ; oboInOwl:hasExactSynonym "Influenza with other manifestations"@en, "flu"@en, "influenza with non-respiratory manifestation"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:8469" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "influenza" ; rdfs:subClassOf obo:DOID_1579, obo:DOID_934 . obo:DOID_8557 obo:IAO_0000115 "A pharynx cancer that is located_in the oropharynx." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:8684", "DOID:8851", "DOID:8949", "DOID:9168" ; oboInOwl:hasDbXref "ICD10CM:C10", "ICD10CM:C10.2", "ICD10CM:C10.3", "ICD10CM:C10.8", "ICD9CM:146", "ICD9CM:146.5", "ICD9CM:146.6", "ICD9CM:146.7", "NCI:C7398", "SNOMEDCT_US_2023_03_01:187686007", "SNOMEDCT_US_2023_03_01:93933005", "SNOMEDCT_US_2023_03_01:93971002", "UMLS_CUI:C0153382", "UMLS_CUI:C0153388", "UMLS_CUI:C0153389", "UMLS_CUI:C0153390" ; oboInOwl:hasExactSynonym "Oropharyngeal carcinoma"@en, "malignant Oropharyngeal tumor"@en, "malignant tumor of oropharynx"@en, "malignant tumour of mesopharynx"@en, "oropharyngeal cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:8557" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "oropharynx cancer" ; rdfs:subClassOf obo:DOID_0060119 . obo:DOID_863 obo:IAO_0000115 "A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:G98", "ICD9CM:349.9", "MESH:D009422", "NCI:C26835", "SNOMEDCT_US_2023_03_01:155262005", "UMLS_CUI:C0027765" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:863" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "nervous system disease" ; rdfs:subClassOf obo:DOID_7 . obo:DOID_9256 obo:IAO_0000115 "A large intestine cancer that is located_in the colon and/or located_in the rectum." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "ICD10CM:C18.9", "KEGG:05210", "MESH:D015179", "NCI:C2956", "NCI:C4978", "OMIM:114500", "SNOMEDCT_US_2023_03_01:126837005", "SNOMEDCT_US_2023_03_01:93854002", "UMLS_CUI:C0009404", "UMLS_CUI:C0346629" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:9256" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:comment """Xref MGI. OMIM mapping confirmed by DO. [SN].""" ; rdfs:label "colorectal cancer" ; rdfs:subClassOf obo:DOID_10155 . obo:DOID_9261 obo:IAO_0000115 "A pharynx cancer that is located in the nasopharynx, the uppermost region of the pharynx or throat, where the nasal passages and auditory tubes join the remainder of the upper respiratory tract." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:8813", "DOID:8814", "DOID:9057", "DOID:9144", "DOID:9197", "DOID:9229" ; oboInOwl:hasDbXref "GARD:7163", "ICD10CM:C11", "ICD10CM:C11.0", "ICD10CM:C11.1", "ICD10CM:C11.2", "ICD10CM:C11.3", "ICD9CM:147", "ICD9CM:147.0", "ICD9CM:147.1", "ICD9CM:147.2", "ICD9CM:147.3", "MESH:D009303", "NCI:C9321", "OMIM:161550", "OMIM:607107", "ORDO:150", "SNOMEDCT_US_2023_03_01:187692001", "SNOMEDCT_US_2023_03_01:187693006", "SNOMEDCT_US_2023_03_01:187700006", "SNOMEDCT_US_2023_03_01:363398003", "SNOMEDCT_US_2023_03_01:93919005", "SNOMEDCT_US_2023_03_01:94078000", "UMLS_CUI:C0153392", "UMLS_CUI:C0153393", "UMLS_CUI:C0153394", "UMLS_CUI:C0153395", "UMLS_CUI:C0153396", "UMLS_CUI:C0238301" ; oboInOwl:hasExactSynonym "Nasopharyngeal carcinoma"@en, "malignant Nasopharyngeal tumor"@en, "malignant neoplasm of nasopharynx"@en, "nasopharynx cancer"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:hasRelatedSynonym "carcinoma of nasopharynx"@en ; oboInOwl:id "DOID:9261" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:comment """Xref MGI. OMIM mapping confirmed by DO. [SN].""" ; rdfs:label "nasopharynx carcinoma" ; rdfs:subClassOf obo:DOID_0050615, obo:DOID_0060119, obo:DOID_305 . obo:DOID_934 obo:IAO_0000115 "A disease by infectious agent that results in infection, has_material_basis_in Viruses." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "DOID:1329" ; oboInOwl:hasDbXref "ICD10CM:A94", "ICD10CM:B34.9", "ICD9CM:060-066.99", "MESH:D001102", "MESH:D014777", "NCI:C3439", "NCI:C34396", "SNOMEDCT_US_2023_03_01:34014006", "SNOMEDCT_US_2023_03_01:40610006", "UMLS_CUI:C0003723", "UMLS_CUI:C0042769" ; oboInOwl:hasExactSynonym "Viral Infection"@en, "Viral disease"@en, "virus infection"@en ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:934" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "viral infectious disease" ; rdfs:subClassOf obo:DOID_0050117 . obo:DOID_9538 obo:IAO_0000115 "A myeloid neoplasm that is located_in the plasma cells in bone marrow." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EFO:0001378", "GARD:7108", "ICD10CM:C90.0", "ICD9CM:203.0", "MESH:D009101", "NCI:C3242", "OMIM:254500", "ORDO:29073", "SNOMEDCT_US_2023_03_01:94705007", "UMLS_CUI:C0026764" ; oboInOwl:hasExactSynonym "myeloma" ; oboInOwl:hasOBONamespace "disease_ontology" ; oboInOwl:id "DOID:9538" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:comment "OMIM mapping confirmed by DO. [SN]." ; rdfs:label "multiple myeloma" ; rdfs:subClassOf obo:DOID_4960 . obo:FMA_12278 obo:IAO_0000412 ; oboInOwl:hasOBONamespace "fma" ; oboInOwl:id "FMA:12278" ; a owl:Class ; rdfs:label "Hormone" ; rdfs:subClassOf obo:CHEBI_23367 . obo:GO_0002250 obo:IAO_0000115 "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "Wikipedia:Adaptive_immune_system" ; oboInOwl:hasExactSynonym "acquired immune response", "immune memory response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002250" ; a owl:Class ; rdfs:label "adaptive immune response" ; rdfs:subClassOf obo:GO_0006955 . obo:GO_0002385 obo:IAO_0000115 "An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "GO:0002386", "GO:0002422" ; oboInOwl:hasNarrowSynonym "immune response in MALT", "immune response in mucosal-associated lymphoid tissue", "immune response in urogenital tract" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002385" ; a owl:Class ; rdfs:label "mucosal immune response" ; rdfs:subClassOf obo:GO_0006955 . obo:GO_0006955 obo:IAO_0000115 "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006955" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "immune response" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0008150 obo:IAO_0000115 "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24968"^^xsd:anyURI ; obo:IAO_0000412 ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T15:05:24Z" ; oboInOwl:hasAlternativeId "GO:0000004", "GO:0007582", "GO:0044699" ; oboInOwl:hasDbXref "Wikipedia:Biological_process" ; oboInOwl:hasExactSynonym "biological process", "physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism process", "single-organism process" ; oboInOwl:id "GO:0008150" ; oboInOwl:inSubset , , , , , , ; a owl:Class ; rdfs:comment "Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ; rdfs:label "biological_process" ; rdfs:subClassOf obo:BFO_0000015 . obo:GO_0019814 obo:IAO_0000115 "A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ; obo:IAO_0000412 ; oboInOwl:hasNarrowSynonym "antibody" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0019814" ; oboInOwl:inSubset ; a owl:Class ; rdfs:comment "Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available." ; rdfs:label "immunoglobulin complex" ; rdfs:subClassOf obo:GO_0032991 . obo:GO_0032991 obo:IAO_0000115 "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "GO:0043234" ; oboInOwl:hasExactSynonym "macromolecular complex", "macromolecule complex", "protein containing complex" ; oboInOwl:hasNarrowSynonym "protein complex", "protein-protein complex" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032991" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:comment "A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole." ; rdfs:label "protein-containing complex" ; rdfs:subClassOf obo:BFO_0000040 . obo:GO_0050896 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "GO:0051869" ; oboInOwl:hasExactSynonym "physiological response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050896" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to stimulus" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0071735 obo:IAO_0000115 "A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ; obo:IAO_0000412 ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-24T01:44:53Z" ; oboInOwl:hasNarrowSynonym "IgG1", "IgG2", "IgG2a", "IgG2b", "IgG2c", "IgG3", "IgG4" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071735" ; a owl:Class ; rdfs:comment "Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species." ; rdfs:label "IgG immunoglobulin complex" ; rdfs:subClassOf obo:GO_0019814 . obo:GO_0071738 obo:IAO_0000115 "A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ; obo:IAO_0000412 ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-24T01:44:53Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071738" ; a owl:Class ; rdfs:comment "Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available." ; rdfs:label "IgD immunoglobulin complex" ; rdfs:subClassOf obo:GO_0019814 . obo:GO_0071742 obo:IAO_0000115 "A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ; obo:IAO_0000412 ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-24T01:44:53Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071742" ; a owl:Class ; rdfs:comment "Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available." ; rdfs:label "IgE immunoglobulin complex" ; rdfs:subClassOf obo:GO_0019814 . obo:GO_0071745 obo:IAO_0000115 "A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ; obo:IAO_0000412 ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-24T01:44:53Z" ; oboInOwl:hasNarrowSynonym "IgA1 antibody", "IgA2 antibody" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071745" ; a owl:Class ; rdfs:comment "Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available." ; rdfs:label "IgA immunoglobulin complex" ; rdfs:subClassOf obo:GO_0019814 . obo:GO_0071753 obo:IAO_0000115 "A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." ; obo:IAO_0000412 ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-24T01:44:53Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071753" ; a owl:Class ; rdfs:comment "Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available." ; rdfs:label "IgM immunoglobulin complex" ; rdfs:subClassOf obo:GO_0019814 . obo:IAO_0000001 obo:IAO_0000111 "conditional specification"@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A directive information entity that specifies what should happen if the trigger condition is fulfilled."@en ; obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ; obo:IAO_0000119 "OBI branch derived"@en, "OBI_0000349"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "conditional specification"@en ; rdfs:subClassOf obo:IAO_0000033 . obo:IAO_0000002 obo:IAO_0000111 "example to be eventually removed"@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "example to be eventually removed"@en . obo:IAO_0000003 obo:IAO_0000111 "measurement unit label"@en ; obo:IAO_0000112 "Examples of measurement unit labels are liters, inches, weight per volume."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure."@en ; obo:IAO_0000116 """2009-03-16: provenance: a term measurement unit was proposed for OBI (OBI_0000176) , edited by Chris Stoeckert and Cristian Cocos, and subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definition of this, different, term."""@en, "2009-03-16: review of this term done during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI."@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "measurement unit label"@en ; rdfs:subClassOf obo:IAO_0000009 . obo:IAO_0000005 obo:IAO_0000111 "objective specification"@en ; obo:IAO_0000112 "In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved."@en ; obo:IAO_0000116 "2009-03-16: original definition when imported from OBI read: \"objective is an non realizable information entity which can serve as that proper part of a plan towards which the realization of the plan is directed.\""@en, "2014-03-31: In the example of usage (\"In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction\") there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that."@en, "Answers the question, why did you do this experiment?"@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Barry Smith"@en, "PERSON: Bjoern Peters"@en, "PERSON: Jennifer Fostel"@en ; obo:IAO_0000118 "goal specification"@en ; obo:IAO_0000119 "OBI Plan and Planned Process/Roles Branch"@en, "OBI_0000217"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "objective specification"@en ; rdfs:subClassOf obo:IAO_0000033 . obo:IAO_0000007 obo:IAO_0000112 "Pour the contents of flask 1 into flask 2"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A directive information entity that describes an action the bearer will take."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "OBI Plan and Planned Process branch"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "action specification"@en ; rdfs:subClassOf obo:IAO_0000033 . obo:IAO_0000009 obo:IAO_0000111 "datum label"@en ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "A label is a symbol that is part of some other datum and is used to either partially define the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label"@en ; obo:IAO_0000116 "http://www.golovchenko.org/cgi-bin/wnsearch?q=label#4n"@en ; obo:IAO_0000117 "GROUP: IAO"@en ; obo:IAO_0000232 """9/22/11 BP: changed the rdfs:label for this class from 'label' to 'datum label' to convey that this class is not intended to cover all kinds of labels (stickers, radiolabels, etc.), and not even all kind of textual labels, but rather the kind of labels occuring in a datum. """ ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "datum label"@en ; rdfs:subClassOf obo:IAO_0000030 . obo:IAO_0000013 obo:IAO_0000111 "journal article"@en ; obo:IAO_0000112 "Examples are articles published in the journals, Nature and Science. The content can often be cited by reference to a paper based encoding, e.g. Authors, Title of article, Journal name, date or year of publication, volume and page number."@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A report that is published in a journal."@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Chris Stoeckert"@en ; obo:IAO_0000119 "OBI_0000159"@en, "group:OBI"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "journal article"@en ; rdfs:subClassOf obo:IAO_0000088, obo:IAO_0000311 . obo:IAO_0000027 obo:IAO_0000111 "data item"@en ; obo:IAO_0000112 "Data items include counts of things, analyte concentrations, and statistical summaries."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ; obo:IAO_0000116 "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers."@en, "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum."@en, "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym."@en, "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/", """JAR: datum -- well, this will be very tricky to define, but maybe some information-like stuff that might be put into a computer and that is meant, by someone, to denote and/or to be interpreted by some process... I would include lists, tables, sentences... I think I might defer to Barry, or to Brian Cantwell Smith JAR: A data item is an approximately justified approximately true approximate belief"""@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Chris Stoeckert"@en, "PERSON: Jonathan Rees"@en ; obo:IAO_0000118 "data"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "data item"@en ; rdfs:subClassOf obo:IAO_0000030 . obo:IAO_0000030 obo:IAO_0000111 "information content entity"@en ; obo:IAO_0000112 "Examples of information content entites include journal articles, data, graphical layouts, and graphs."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A generically dependent continuant that is about some thing."@en ; obo:IAO_0000116 "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)."@en, """information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907). Previous. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity."""@en ; obo:IAO_0000117 "PERSON: Chris Stoeckert"@en ; obo:IAO_0000119 "OBI_0000142"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "information content entity"@en ; rdfs:subClassOf obo:BFO_0000031 . obo:IAO_0000032 obo:IAO_0000112 "10 feet. 3 ml."@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label."@en ; obo:IAO_0000116 """2009-03-16: we decided to keep datum singular in scalar measurement datum, as in this case we explicitly refer to the singular form"""@en, "Would write this as: has_part some 'measurement unit label' and has_part some numeral and has_part exactly 2, except for the fact that this won't let us take advantage of OWL reasoning over the numbers. Instead use has measurment value property to represent the same. Use has measurement unit label (subproperty of has_part) so we can easily say that there is only one of them."@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "scalar measurement datum"@en ; rdfs:subClassOf obo:IAO_0000109 . obo:IAO_0000033 obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An information content entity whose concretizations indicate to their bearer how to realize them in a process."@en ; obo:IAO_0000116 "2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was \"is the specification of a process that can be concretized and realized by an actor\" with alternative term \"instruction\".It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term."@en, "2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it."@en, "8/6/2009 Alan Ruttenberg: Changed label from \"information entity about a realizable\" after discussions at ICBO"@en, "Werner pushed back on calling it realizable information entity as it isn't realizable. However this name isn't right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn't about the plan, it, once concretized, *is* the plan. -Alan"@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bjoern Peters"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "directive information entity"@en ; rdfs:subClassOf obo:IAO_0000030 . obo:IAO_0000064 obo:IAO_0000111 "algorithm"@en ; obo:IAO_0000112 "PMID: 18378114.Genomics. 2008 Mar 28. LINKGEN: A new algorithm to process data in genetic linkage studies."@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata."@en ; obo:IAO_0000117 "Philippe Rocca-Serra"@en, "PlanAndPlannedProcess Branch"@en ; obo:IAO_0000119 "OBI_0000270"@en, "adapted from discussion on OBI list (Matthew Pocock, Christian Cocos, Alan Ruttenberg)"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "algorithm"@en ; rdfs:subClassOf obo:IAO_0000104 . obo:IAO_0000078 obo:IAO_0000111 "curation status specification"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ; obo:IAO_0000116 "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)"@en ; obo:IAO_0000117 "PERSON:Bill Bug"@en ; obo:IAO_0000119 "GROUP:OBI:"@en, "OBI_0000266"@en ; a owl:Class ; rdfs:label "curation status specification"@en ; rdfs:subClassOf obo:IAO_0000102 ; owl:equivalentClass [ a owl:Class ; owl:oneOf (obo:IAO_0000002 obo:IAO_0000120 obo:IAO_0000121 obo:IAO_0000122 obo:IAO_0000123 obo:IAO_0000124 obo:IAO_0000125 obo:IAO_0000423 obo:IAO_0000428 ) ] . obo:IAO_0000088 obo:IAO_0000111 "report"@en ; obo:IAO_0000112 "Examples of reports are gene lists and investigation reports. These are not published (journal) articles but may be included in a journal article."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record)."@en ; obo:IAO_0000116 """2009-03-16: comment from Darren Natale: I am slightly uneasy with the sentence \"Topic of the report is on something that has completed.\" Should it be restricted to those things that are completed? For example, a progress report is (usually) about something that definitely has *not* been completed, or may include (only) projections. I think the definition would not suffer if the whole sentence is deleted."""@en, "2009-03-16: this was report of results with definition: A report is a narrative object that is a formal statement of the results of an investigation, or of any matter on which definite information is required, made by some person or body instructed or required to do so."@en, "2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify this definition please notify OBI."@en, "2009-08-10 Alan Ruttenberg: Larry Hunter suggests that this be obsoleted and replaced by 'document'. Alan restored as there are OBI dependencies and this merits further discussion"@en, "disagreement about where reports go. alan: only some gene lists are reports. Is a report all the content of some document? The example of usage suggests that a report may be part of some article. Term needs clarification"@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Chris Stoeckert"@en, "PERSON: Melanie Courtot"@en ; obo:IAO_0000119 "GROUP: OBI"@en, "OBI_0000099"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "report"@en ; rdfs:subClassOf obo:IAO_0000310 . obo:IAO_0000100 obo:IAO_0000111 "data set"@en ; obo:IAO_0000112 "Intensity values in a CEL file or from multiple CEL files comprise a data set (as opposed to the CEL files themselves)."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets."@en ; obo:IAO_0000116 "2009/10/23 Alan Ruttenberg. The intention is that this term represent collections of like data. So this isn't for, e.g. the whole contents of a cel file, which includes parameters, metadata etc. This is more like java arrays of a certain rather specific type"@en, "2014-05-05: Data sets are aggregates and thus must include two or more data items. We have chosen not to add logical axioms to make this restriction." ; obo:IAO_0000117 "person:Allyson Lister"@en, "person:Chris Stoeckert"@en ; obo:IAO_0000119 "OBI_0000042"@en, "group:OBI"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "data set"@en ; rdfs:subClassOf obo:IAO_0000027 . obo:IAO_0000102 obo:IAO_0000111 "data about an ontology part"@en ; obo:IAO_0000115 "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; a owl:Class ; rdfs:label "data about an ontology part"@en ; rdfs:subClassOf obo:IAO_0000027 . obo:IAO_0000103 obo:IAO_0000111 "failed exploratory term"@en ; obo:IAO_0000115 "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "failed exploratory term"@en . obo:IAO_0000104 obo:IAO_0000111 "plan specification"@en ; obo:IAO_0000112 "PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified."@en ; obo:IAO_0000116 "2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was \" a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan\". It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term."@en, "2014-03-31: A plan specification can have other parts, such as conditional specifications."@en, "2022-01-16 Updated definition to that proposed by Clint Dowloand, IAO Issue 231."@en, "Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved"@en ; obo:IAO_0000117 "Alan Ruttenberg"@en, "Clint Dowland"@en ; obo:IAO_0000119 "OBI Plan and Planned Process branch"@en, "OBI_0000344"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:comment """2/3/2009 Comment from OBI review. Action specification not well enough specified. Conditional specification not well enough specified. Question whether all plan specifications have objective specifications. Request that IAO either clarify these or change definitions not to use them"""@en ; rdfs:label "plan specification"@en ; rdfs:seeAlso "https://github.com/information-artifact-ontology/IAO/issues/231#issuecomment-1010455131"@en ; rdfs:subClassOf obo:IAO_0000033 . obo:IAO_0000109 obo:IAO_0000111 "measurement datum"@en ; obo:IAO_0000112 "Examples of measurement data are the recoding of the weight of a mouse as {40,mass,\"grams\"}, the recording of an observation of the behavior of the mouse {,process,\"agitated\"}, the recording of the expression level of a gene as measured through the process of microarray experiment {3.4,luminosity,}."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device."@en ; obo:IAO_0000116 "2/2/2009 is_specified_output of some assay?"@en ; obo:IAO_0000117 "person:Chris Stoeckert"@en ; obo:IAO_0000119 "OBI_0000305"@en, "group:OBI"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "measurement datum"@en ; rdfs:subClassOf obo:IAO_0000027 . obo:IAO_0000111 obo:IAO_0000111 "editor preferred term"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)"@en ; obo:IAO_0000117 "PERSON:Daniel Schober"@en ; obo:IAO_0000119 "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "editor preferred term"@en . obo:IAO_0000112 obo:IAO_0000111 "example of usage"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en ; obo:IAO_0000117 "PERSON:Daniel Schober"@en ; obo:IAO_0000119 "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "example of usage"@en . obo:IAO_0000113 obo:IAO_0000111 "in branch"@en ; obo:IAO_0000115 "An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet."@en ; obo:IAO_0000117 "GROUP:OBI"@en ; obo:IAO_0000119 "OBI_0000277"@en ; a owl:AnnotationProperty ; rdfs:label "in branch"@en . obo:IAO_0000114 obo:IAO_0000111 "has curation status"@en ; obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Bill Bug"@en, "PERSON:Melanie Courtot"@en ; a owl:AnnotationProperty ; rdfs:label "has curation status"@en . obo:IAO_0000115 obo:IAO_0000111 "definition"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ; obo:IAO_0000116 """2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with."""@en, """2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. """@en ; obo:IAO_0000117 "PERSON:Daniel Schober"@en ; obo:IAO_0000119 "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "definition"@en . obo:IAO_0000116 obo:IAO_0000111 "editor note"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en ; obo:IAO_0000117 "PERSON:Daniel Schober"@en ; obo:IAO_0000119 "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "editor note"@en . obo:IAO_0000117 obo:IAO_0000111 "term editor"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people"@en ; obo:IAO_0000116 "20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115."@en ; obo:IAO_0000117 "PERSON:Daniel Schober"@en ; obo:IAO_0000119 "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "term editor"@en . obo:IAO_0000118 obo:IAO_0000111 "alternative label"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like."@en ; obo:IAO_0000117 "OBO Operations committee", "PERSON:Daniel Schober"@en ; obo:IAO_0000119 "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:comment "Consider re-defing to: An alternative name for a class or property which can mean the same thing as the preferred name (semantically equivalent, narrow, broad or related)." ; rdfs:isDefinedBy ; rdfs:label "alternative label"@en . obo:IAO_0000119 obo:IAO_0000111 "definition source"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007"@en ; obo:IAO_0000117 "PERSON:Daniel Schober"@en ; obo:IAO_0000119 "Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w"@en, "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "definition source"@en . obo:IAO_0000120 obo:IAO_0000111 "metadata complete"@en ; obo:IAO_0000115 "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "metadata complete"@en . obo:IAO_0000121 obo:IAO_0000111 "organizational term"@en ; obo:IAO_0000115 "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "organizational term"@en . obo:IAO_0000122 obo:IAO_0000111 "ready for release"@en ; obo:IAO_0000115 "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "ready for release"@en . obo:IAO_0000123 obo:IAO_0000111 "metadata incomplete"@en ; obo:IAO_0000115 "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "metadata incomplete"@en . obo:IAO_0000124 obo:IAO_0000111 "uncurated"@en ; obo:IAO_0000115 "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "uncurated"@en . obo:IAO_0000125 obo:IAO_0000111 "pending final vetting"@en ; obo:IAO_0000115 "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "pending final vetting"@en . obo:IAO_0000136 obo:IAO_0000112 "This document is about information artifacts and their representations"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A (currently) primitive relation that relates an information artifact to an entity."@en ; obo:IAO_0000116 """7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of \"mentions\" relation. Weaken the is_about relationship to be primitive. We will try to build it back up by elaborating the various subproperties that are more precisely defined. Some currently missing phenomena that should be considered \"about\" are predications - \"The only person who knows the answer is sitting beside me\" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic."""@en ; obo:IAO_0000117 "person:Alan Ruttenberg"@en ; obo:IAO_0000119 "Smith, Ceusters, Ruttenberg, 2000 years of philosophy"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "is about"@en . obo:IAO_0000142 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "An information artifact IA mentions an entity E exactly when it has a component/part that denotes E"@en ; obo:IAO_0000116 "7/6/2009 Alan Ruttenberg. P4 RC1 munges our GCI so remove it for now: mentions some entity equivalentTo has_part some ('generically denotes' some entity)"@en, "7/6/2009 Alan Ruttenberg: Add this relation following conversation with Jonathan Rees that N&S GCI for is_about was too strong. Really it was simply sufficient. To effect this change we introduce this relation, which is subproperty of is_about, and have previous GCI use this relation \"mentions\" in it's (logical) definition"@en ; obo:IAO_0000117 "PERSON: Jonathan Rees"@en, "Person: Alan Ruttenberg"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "mentions"@en ; rdfs:subPropertyOf obo:IAO_0000136 . obo:IAO_0000224 obo:IAO_0000115 "Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes."@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ; obo:IAO_0000231 obo:IAO_0000226 ; a owl:NamedIndividual ; rdfs:label "obsolete_core"@en ; owl:deprecated true . obo:IAO_0000225 obo:IAO_0000111 "obsolescence reason specification"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ; obo:IAO_0000116 "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology."@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ; a owl:Class ; rdfs:label "obsolescence reason specification"@en ; rdfs:subClassOf obo:IAO_0000102 ; owl:equivalentClass [ a owl:Class ; owl:oneOf (obo:IAO_0000103 obo:IAO_0000226 obo:IAO_0000227 obo:IAO_0000228 obo:IAO_0000229 obo:OMO_0001000 ) ] . obo:IAO_0000226 obo:IAO_0000111 "placeholder removed"@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "placeholder removed"@en . obo:IAO_0000227 obo:IAO_0000111 "terms merged"@en ; obo:IAO_0000116 "An editor note should explain what were the merged terms and the reason for the merge."@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "terms merged"@en . obo:IAO_0000228 obo:IAO_0000111 "term imported"@en ; obo:IAO_0000116 "This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use."@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "term imported"@en . obo:IAO_0000229 obo:IAO_0000111 "term split"@en ; obo:IAO_0000116 "This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created."@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "term split"@en . obo:IAO_0000231 obo:IAO_0000111 "has obsolescence reason"@en ; obo:IAO_0000115 "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ; obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Melanie Courtot"@en ; a owl:AnnotationProperty ; rdfs:label "has obsolescence reason"@en . obo:IAO_0000232 obo:IAO_0000111 "curator note"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An administrative note of use for a curator but of no use for a user"@en ; obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "curator note"@en . obo:IAO_0000233 obo:IAO_0000111 "term tracker item"@en ; obo:IAO_0000112 "the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "An IRI or similar locator for a request or discussion of an ontology term."@en ; obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en ; obo:IAO_0000119 "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:comment "The 'tracker item' can associate a tracker with a specific ontology term."@en ; rdfs:label "term tracker item"@en . obo:IAO_0000234 obo:IAO_0000111 "ontology term requester"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition."@en ; obo:IAO_0000117 "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en ; obo:IAO_0000119 "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:comment "The 'term requester' can credit the person, organization or project who request the ontology term." ; rdfs:label "ontology term requester"@en . obo:IAO_0000310 obo:IAO_0000111 "document"@en ; obo:IAO_0000112 "A journal article, patent application, laboratory notebook, or a book"@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A collection of information content entities intended to be understood together as a whole"@en ; obo:IAO_0000117 "PERSON: Lawrence Hunter"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "document"@en ; rdfs:subClassOf obo:IAO_0000030 . obo:IAO_0000311 obo:IAO_0000111 "publication"@en ; obo:IAO_0000112 "journal article, newspaper story, book, etc."@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A document that is the output of a publishing process."@en ; obo:IAO_0000117 "PERSON: Chris Stoeckert"@en, "PERSON: Jie Zheng"@en, "PERSON: Lawrence Hunter"@en ; obo:IAO_0000118 "published document"@en ; obo:IAO_0000233 ; obo:IAO_0000412 ; a owl:Class ; rdfs:comment "Revisit the term in Octorber 2020. Improve the defintion."@en ; rdfs:label "publication"@en ; rdfs:subClassOf obo:IAO_0000310 . obo:IAO_0000409 obo:IAO_0000111 "denotator type"@en ; obo:IAO_0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities."@en ; obo:IAO_0000115 "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "Barry Smith, Werner Ceusters"@en ; a owl:Class ; rdfs:label "denotator type"@en ; rdfs:subClassOf obo:IAO_0000102 ; owl:equivalentClass [ a owl:Class ; owl:oneOf (obo:IAO_0000410 obo:IAO_0000420 obo:IAO_0000421 ) ] . obo:IAO_0000410 obo:IAO_0000111 "universal"@en ; obo:IAO_0000116 "Hard to give a definition for. Intuitively a \"natural kind\" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf"@en ; a obo:IAO_0000409, owl:NamedIndividual ; rdfs:label "universal"@en . obo:IAO_0000411 obo:IAO_0000111 "is denotator type"@en ; obo:IAO_0000115 "Relates an class defined in an ontology, to the type of it's denotator"@en ; obo:IAO_0000116 "In OWL 2 add AnnotationPropertyRange('is denotator type' 'denotator type')"@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:label "is denotator type"@en . obo:IAO_0000412 obo:IAO_0000111 "imported from"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "For external terms/classes, the ontology from which the term was imported"@en ; obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Melanie Courtot"@en ; obo:IAO_0000119 "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "imported from"@en . obo:IAO_0000420 obo:IAO_0000111 "defined class"@en ; obo:IAO_0000115 "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en ; obo:IAO_0000116 "\"definitions\", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; a obo:IAO_0000409, owl:NamedIndividual ; rdfs:label "defined class"@en . obo:IAO_0000421 obo:IAO_0000111 "named class expression"@en ; obo:IAO_0000115 "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en ; obo:IAO_0000116 "named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions"@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; a obo:IAO_0000409, owl:NamedIndividual ; rdfs:label "named class expression"@en . obo:IAO_0000423 obo:IAO_0000111 "to be replaced with external ontology term"@en ; obo:IAO_0000115 "Terms with this status should eventually replaced with a term from another ontology."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "group:OBI"@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "to be replaced with external ontology term"@en . obo:IAO_0000424 obo:IAO_0000111 "expand expression to"@en ; obo:IAO_0000112 """ObjectProperty: RO_0002104 Label: has plasma membrane part Annotations: IAO_0000424 \"http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)\" """@en ; obo:IAO_0000115 "A macro expansion tag applied to an object property (or possibly a data property) which can be used by a macro-expansion engine to generate more complex expressions from simpler ones"@en ; obo:IAO_0000117 "Chris Mungall"@en ; a owl:AnnotationProperty ; rdfs:label "expand expression to"@en . obo:IAO_0000425 obo:IAO_0000111 "expand assertion to"@en ; obo:IAO_0000112 """ObjectProperty: RO??? Label: spatially disjoint from Annotations: expand_assertion_to \"DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X) (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)\" """@en ; obo:IAO_0000115 "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en ; obo:IAO_0000117 "Chris Mungall"@en ; a owl:AnnotationProperty ; rdfs:label "expand assertion to"@en . obo:IAO_0000426 obo:IAO_0000111 "first order logic expression"@en ; obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:label "first order logic expression"@en . obo:IAO_0000427 obo:IAO_0000111 "antisymmetric property"@en ; obo:IAO_0000112 "part_of antisymmetric property xsd:true"@en ; obo:IAO_0000115 "Use boolean value xsd:true to indicate that the property is an antisymmetric property"@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:label "antisymmetric property"@en ; rdfs:subPropertyOf obo:OMO_0001001 . obo:IAO_0000428 obo:IAO_0000111 "requires discussion"@en ; obo:IAO_0000115 "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "group:OBI"@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "requires discussion"@en . obo:IAO_0000589 obo:IAO_0000111 "OBO foundry unique label"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "An alternative name for a class or property which is unique across the OBO Foundry."@en ; obo:IAO_0000116 "The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools ."@en ; obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Bjoern Peters"@en, "PERSON:Chris Mungall"@en, "PERSON:Melanie Courtot"@en ; obo:IAO_0000119 "GROUP:OBO Foundry "@en ; a owl:AnnotationProperty ; rdfs:label "OBO foundry unique label"@en . obo:IAO_0000596 obo:IAO_0000111 "has ID digit count"@en ; obo:IAO_0000112 """Ontology: Annotations: 'has ID prefix': \"http://purl.obolibrary.org/obo/RO_\" 'has ID digit count' : 7, rdfs:label \"RO id policy\" 'has ID policy for': \"RO\""""@en ; obo:IAO_0000115 "Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix\" annotation property value concatenated with an integer in the id range (left padded with \"0\"s to make this many digits)"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:label "has ID digit count"@en . obo:IAO_0000597 obo:IAO_0000111 "has ID range allocated"@en ; obo:IAO_0000112 """Datatype: idrange:1 Annotations: 'has ID range allocated to': \"Chris Mungall\" EquivalentTo: xsd:integer[> 2151 , <= 2300] """@en ; obo:IAO_0000115 "Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:label "has ID range allocated to"@en . obo:IAO_0000598 obo:IAO_0000111 "has ID policy for"@en ; obo:IAO_0000112 """Ontology: Annotations: 'has ID prefix': \"http://purl.obolibrary.org/obo/RO_\" 'has ID digit count' : 7, rdfs:label \"RO id policy\" 'has ID policy for': \"RO\""""@en ; obo:IAO_0000115 "Relating an ontology used to record id policy to the ontology namespace whose policy it manages"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:label "has ID policy for"@en . obo:IAO_0000599 obo:IAO_0000111 "has ID prefix"@en ; obo:IAO_0000112 """Ontology: Annotations: 'has ID prefix': \"http://purl.obolibrary.org/obo/RO_\" 'has ID digit count' : 7, rdfs:label \"RO id policy\" 'has ID policy for': \"RO\""""@en ; obo:IAO_0000115 "Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with \"0\"s to make this many digits) to construct an ID for a term being created."@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:label "has ID prefix"@en . obo:IAO_0000600 obo:IAO_0000111 "elucidation"@en ; obo:IAO_0000117 "person:Alan Ruttenberg"@en ; obo:IAO_0000119 "Person:Barry Smith"@en ; obo:IAO_0000600 "Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "elucidation"@en . obo:IAO_0000601 obo:IAO_0000111 "has associated axiom(nl)"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; obo:IAO_0000119 "Person:Alan Ruttenberg"@en ; obo:IAO_0000600 "An axiom associated with a term expressed using natural language"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "has associated axiom(nl)"@en . obo:IAO_0000602 obo:IAO_0000111 "has associated axiom(fol)"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; obo:IAO_0000119 "Person:Alan Ruttenberg"@en ; obo:IAO_0000600 "An axiom expressed in first order logic using CLIF syntax"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "has associated axiom(fol)"@en . obo:IAO_0000603 obo:IAO_0000111 "is allocated id range"@en ; obo:IAO_0000115 "Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. \"IAO_0020000-IAO_0020999\""@en ; obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:comment "Add as annotation triples in the granting ontology"@en ; rdfs:label "is allocated id range"@en . obo:IAO_0000700 obo:IAO_0000111 "has ontology root term"@en ; obo:IAO_0000115 "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ; obo:IAO_0000117 "Nicolas Matentzoglu"@en ; a owl:AnnotationProperty ; rdfs:label "has ontology root term"@en . obo:IAO_0006011 obo:IAO_0000111 "may be identical to"@en ; obo:IAO_0000115 "A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged."@en ; obo:IAO_0000117 "David Osumi-Sutherland"@en ; obo:IAO_0000233 "#40"@en ; obo:IAO_0000234 "VFB"@en ; a owl:AnnotationProperty ; rdfs:comment "Edges asserting this should be annotated with to record evidence supporting the assertion and its provenance."@en ; rdfs:label "may be identical to"@en . obo:IAO_0006012 obo:IAO_0000111 "scheduled for obsoletion on or after"@en ; obo:IAO_0000115 "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en ; obo:IAO_0000117 "Chris Mungall, Jie Zheng"@en ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/15532"@en, "https://github.com/information-artifact-ontology/ontology-metadata/issues/32"@en ; obo:IAO_0000234 "GO ontology"@en ; a owl:AnnotationProperty ; rdfs:label "scheduled for obsoletion on or after"@en ; rdfs:range xsd:dateTime . obo:IAO_0010000 obo:IAO_0000111 "has axiom id"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; obo:IAO_0000119 "Person:Alan Ruttenberg"@en ; obo:IAO_0000600 "A URI that is intended to be unique label for an axiom used for tracking change to the ontology. For an axiom expressed in different languages, each expression is given the same URI"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "has axiom label"@en . obo:IAO_0100001 obo:IAO_0000111 "term replaced by"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; obo:IAO_0000119 "Person:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:comment "Add as annotation triples in the granting ontology"@en ; rdfs:label "term replaced by"@en . obo:IAO_8000000 obo:IAO_0000111 "ontology module"@en ; obo:IAO_0000116 "I have placed this under 'data about an ontology part', but this can be discussed. I think this is OK if 'part' is interpreted reflexively, as an ontology module is the whole ontology rather than part of it."@en ; obo:IAO_0000118 "ontology file"@en ; obo:IAO_0000232 "This class and it's subclasses are applied to OWL ontologies. Using an rdf:type triple will result in problems with OWL-DL. I propose that dcterms:type is instead used to connect an ontology URI with a class from this hierarchy. The class hierarchy is not disjoint, so multiple assertions can be made about a single ontology."@en ; a owl:Class ; rdfs:label "ontology module"@en ; rdfs:subClassOf obo:IAO_0000102 . obo:IAO_8000001 obo:IAO_0000111 "base ontology module"@en ; obo:IAO_0000115 "An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies."@en ; a owl:Class ; rdfs:label "base ontology module"@en ; rdfs:seeAlso ; rdfs:subClassOf obo:IAO_8000000 . obo:IAO_8000002 obo:IAO_0000111 "editors ontology module"@en ; obo:IAO_0000115 "An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users."@en ; obo:IAO_0000118 "source ontology module"@en ; a owl:Class ; rdfs:label "editors ontology module"@en ; rdfs:subClassOf obo:IAO_8000000 . obo:IAO_8000003 obo:IAO_0000111 "main release ontology module"@en ; obo:IAO_0000115 "An ontology module that is intended to be the primary release product and the one consumed by the majority of tools."@en ; obo:IAO_0000116 "TODO: Add logical axioms that state that a main release ontology module is derived from (directly or indirectly) an editors module"@en ; a owl:Class ; rdfs:label "main release ontology module"@en ; rdfs:subClassOf obo:IAO_8000000 . obo:IAO_8000004 obo:IAO_0000111 "bridge ontology module"@en ; obo:IAO_0000115 "An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module."@en ; a owl:Class ; rdfs:label "bridge ontology module"@en ; rdfs:seeAlso ; rdfs:subClassOf obo:IAO_8000000 . obo:IAO_8000005 obo:IAO_0000111 "import ontology module"@en ; obo:IAO_0000115 "A subset ontology module that is intended to be imported from another ontology."@en ; obo:IAO_0000116 "TODO: add axioms that indicate this is the output of a module extraction process."@en ; obo:IAO_0000118 "import file"@en ; a owl:Class ; rdfs:label "import ontology module"@en ; rdfs:seeAlso ; rdfs:subClassOf obo:IAO_8000006 . obo:IAO_8000006 obo:IAO_0000111 "subset ontology module"@en ; obo:IAO_0000115 "An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms."@en ; obo:IAO_0000118 "ontology slim"@en, "subset ontology"@en ; a owl:Class ; rdfs:label "subset ontology module"@en ; rdfs:seeAlso , ; rdfs:subClassOf obo:IAO_8000000 . obo:IAO_8000007 obo:IAO_0000111 "curation subset ontology module"@en ; obo:IAO_0000115 "A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation."@en ; a owl:Class ; rdfs:label "curation subset ontology module"@en ; rdfs:subClassOf obo:IAO_8000006 . obo:IAO_8000008 obo:IAO_0000111 "analysis ontology module"@en ; obo:IAO_0000115 "An ontology module that is intended for usage in analysis or discovery applications."@en ; a owl:Class ; rdfs:label "analysis subset ontology module"@en ; rdfs:subClassOf obo:IAO_8000006 . obo:IAO_8000009 obo:IAO_0000111 "single layer ontology module"@en ; obo:IAO_0000115 "A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint."@en ; obo:IAO_0000118 "ribbon subset"@en ; a owl:Class ; rdfs:label "single layer subset ontology module"@en ; rdfs:subClassOf obo:IAO_8000006 . obo:IAO_8000010 obo:IAO_0000111 "exclusion subset ontology module"@en ; obo:IAO_0000115 "A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes."@en ; obo:IAO_0000118 "antislim"@en ; a owl:Class ; rdfs:label "exclusion subset ontology module"@en ; rdfs:subClassOf obo:IAO_8000006 . obo:IAO_8000011 obo:IAO_0000111 "external import ontology module"@en ; obo:IAO_0000115 "An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach."@en ; obo:IAO_0000118 "external import"@en ; a owl:Class ; rdfs:label "external import ontology module"@en ; rdfs:subClassOf obo:IAO_8000005 . obo:IAO_8000012 obo:IAO_0000111 "species subset ontology module"@en ; obo:IAO_0000115 "A subset ontology that is crafted to either include or exclude a taxonomic grouping of species."@en ; obo:IAO_0000118 "taxon subset"@en ; a owl:Class ; rdfs:label "species subset ontology module"@en ; rdfs:seeAlso ; rdfs:subClassOf obo:IAO_8000006 . obo:IAO_8000013 obo:IAO_0000111 "reasoned ontology module"@en ; obo:IAO_0000115 "An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available."@en ; a owl:Class ; rdfs:label "reasoned ontology module"@en ; rdfs:seeAlso ; rdfs:subClassOf obo:IAO_8000000 . obo:IAO_8000014 obo:IAO_0000111 "generated ontology module"@en ; obo:IAO_0000115 "An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV."@en ; obo:IAO_0000116 "TODO: Add axioms (using PROV-O?) that indicate this is the output-of some reasoning process"@en ; a owl:Class ; rdfs:label "generated ontology module"@en ; rdfs:subClassOf obo:IAO_8000000 . obo:IAO_8000015 obo:IAO_0000111 "template generated ontology module"@en ; obo:IAO_0000115 "An ontology module that is automatically generated from a template specification and fillers for slots in that template."@en ; a owl:Class ; rdfs:label "template generated ontology module"@en ; rdfs:seeAlso , , ; rdfs:subClassOf obo:IAO_8000014 . obo:IAO_8000016 obo:IAO_0000111 "taxonomic bridge ontology module"@en ; a owl:Class ; rdfs:label "taxonomic bridge ontology module"@en ; rdfs:subClassOf obo:IAO_8000004 . obo:IAO_8000017 obo:IAO_0000111 "ontology module subsetted by expressivity"@en ; a owl:Class ; rdfs:label "ontology module subsetted by expressivity"@en ; rdfs:subClassOf obo:IAO_8000006 . obo:IAO_8000018 obo:IAO_0000111 "obo basic subset ontology module"@en ; obo:IAO_0000115 """A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools. Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses). An ontology is OBO Basic if and only if it has the following characteristics: DAG Unidirectional No Dangling Clauses Fully Asserted Fully Labeled No equivalence axioms Singly labeled edges No qualifier lists No disjointness axioms No owl-axioms header No imports"""@en ; a owl:Class ; rdfs:label "obo basic subset ontology module"@en ; rdfs:seeAlso ; rdfs:subClassOf obo:IAO_8000017 . obo:IAO_8000019 obo:IAO_0000111 "ontology module subsetted by OWL profile"@en ; a owl:Class ; rdfs:label "ontology module subsetted by OWL profile"@en ; rdfs:subClassOf obo:IAO_8000017 . obo:IAO_8000020 obo:IAO_0000111 "EL++ ontology module"@en ; a owl:Class ; rdfs:label "EL++ ontology module"@en ; rdfs:subClassOf obo:IAO_8000019 . obo:IDO_0000403 obo:IAO_0000115 "A symbiont role borne by an organism in virtue of the fact that it derives a growth, survival, or fitness advantage from symbiosis while the other symbiont's growth, survival, or fitness is reduced."@en ; obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ; obo:IAO_0000412 ; a owl:Class ; rdfs:comment "In the medical community, the term 'parasite' is used with the narrower meaning of eukaryotic pathogen.", "The role is realized in processes that result in the parasite's growth, survival, or fitness advantage or in the other organism's growth, survival, or fitness reduction." ; rdfs:label "parasite role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:IDO_0000409 obo:IAO_0000115 "A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis reaches developmental maturity or reproduces sexually in the host. "@en ; obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ; obo:IAO_0000118 "primary host role"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:comment "The role is realized in developmental and reproduction processes of the host's partner in symbiosis." ; rdfs:label "definitive host role"@en ; rdfs:subClassOf obo:OBI_0000725 . obo:IDO_0000418 obo:IAO_0000115 "An infectious agent transporter role that is borne by an organism active in the transfer of an infectious agent to an organism of another Species and in which the agent is infectious."@en ; obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ; obo:IAO_0000412 ; a owl:Class ; rdfs:comment "The role is realized in a transmission process. A bearer of a vector role is also a bearer of a host role." ; rdfs:label "infectious agent vector role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:IDO_0000420 obo:IAO_0000115 "An infectious agent vector role borne by an organism in virtue of the fact that the infectious agent multiplies in the vector."@en ; obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "biological vector of infectious agent role"@en ; rdfs:subClassOf obo:IDO_0000418 . obo:IDO_0000450 obo:IAO_0000115 "A disposition to initiate processes that result in a disorder."@en ; obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ; obo:IAO_0000118 "pathogenicity"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:comment "A pathogenic disposition is realized in processes that create a disorder.", "The use of 'initiates' is intended to convey that a pathogenic disposition is realized when processes resulting in a disorder begin because of some action on the part of the bearer of the disposition. By this interpretation of 'initiates', disorder-causing entities such as glass, UV light, and toxins do not have a pathogenic disposition." ; rdfs:label "pathogenic disposition"@en ; rdfs:subClassOf obo:BFO_0000016 . obo:IDO_0000528 obo:IAO_0000115 "A material entity with a pathogenic disposition."@en ; obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "pathogen"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:IDO_0000547 obo:IAO_0000115 "A biological macromolecule produced by a pathogen and that has a virulence factor disposition."@en ; obo:IAO_0000117 "Albert Goldfain", "Alexander Diehl", "Lindsay Cowell" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "virulence factor"@en ; rdfs:subClassOf obo:CHEBI_23367 . obo:MONDO_0005065 obo:IAO_0000115 "A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "mesothelioma" ; rdfs:subClassOf obo:DOID_14566 . obo:MONDO_0023644 obo:IAO_0000115 "A carcinoma arising in the lip or oral cavity. Most oral cavity carcinomas are squamous cell carcinomas of the tongue, buccal mucosa, or gums. Less frequent morphologic variants include mucoepidermoid carcinoma and adenocarcinoma. Lip carcinomas are usually basal cell or squamous cell carcinomas." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "lip and oral cavity carcinoma" ; rdfs:subClassOf obo:DOID_1542 . obo:NCBITaxon_10090 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:85055" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "house mouse", "mouse" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mus musculus" ; rdfs:subClassOf obo:NCBITaxon_39107 . obo:NCBITaxon_10114 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "rat", "rats" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rattus" ; rdfs:subClassOf obo:NCBITaxon_39107 . obo:NCBITaxon_10141 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:84274" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "domestic guinea pig", "guinea pig" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Cavia aperea porcellus", "Cavia cobaya", "Mus porcellus" ; a owl:Class ; rdfs:label "Cavia porcellus" ; rdfs:subClassOf obo:NCBITaxon_33550 . obo:NCBITaxon_10150 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "chinchillas", "chinchillas and viscachas" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Chinchillidae" ; rdfs:subClassOf obo:NCBITaxon_33550 . obo:NCBITaxon_10239 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superkingdom ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Vira", "Viridae", "viruses" ; a owl:Class ; rdfs:label "Viruses" ; rdfs:subClassOf obo:OBI_0100026 . obo:NCBITaxon_10240 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Poxviridae" ; rdfs:subClassOf obo:NCBITaxon_2732525 . obo:NCBITaxon_10241 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Chordopoxvirinae" ; rdfs:subClassOf obo:NCBITaxon_10240 . obo:NCBITaxon_10242 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthopoxvirus" ; rdfs:subClassOf obo:NCBITaxon_10241 . obo:NCBITaxon_10244 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:130669", "NCBITaxon:130670" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "monkey pox virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Monkeypox virus" ; rdfs:subClassOf obo:NCBITaxon_10242 . obo:NCBITaxon_10245 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "vaccinia virus VV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Vaccinia virus" ; rdfs:subClassOf obo:NCBITaxon_10242 . obo:NCBITaxon_10255 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:12871" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "small pox virus", "smallpox", "smallpox virus", "variola virus VAR" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Variola virus" ; rdfs:subClassOf obo:NCBITaxon_10242 . obo:NCBITaxon_10258 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Contagious pustular dermatitis virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orf virus" ; rdfs:subClassOf obo:NCBITaxon_10241 . obo:NCBITaxon_10260 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Avipoxvirus" ; rdfs:subClassOf obo:NCBITaxon_10241 . obo:NCBITaxon_10261 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "FWPV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avipoxvirus clade A1", "Fowlpoxvirus", "fowl poxvirus", "fowlpox virus FP", "fowlpox virus FPV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Fowlpox virus" ; rdfs:subClassOf obo:NCBITaxon_10260 . obo:NCBITaxon_10264 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Pigeon pox virus", "Pigeon poxvirus", "pigeonpox virus PPV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Pigeonpox virus" ; rdfs:subClassOf obo:NCBITaxon_10260 . obo:NCBITaxon_102793 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "H5N1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "H5N1 subtype" ; rdfs:subClassOf obo:NCBITaxon_11320 . obo:NCBITaxon_10292 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Herpesviridae" ; rdfs:subClassOf obo:NCBITaxon_548681 . obo:NCBITaxon_10293 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Alphaherpesviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Alphaherpesvirinae" ; rdfs:subClassOf obo:NCBITaxon_3044472 . obo:NCBITaxon_10294 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Simplexvirus" ; rdfs:subClassOf obo:NCBITaxon_10293 . obo:NCBITaxon_10298 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "HSV-1", "HSV1" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Herpes simplex virus type 1", "Human herpesvirus type 1", "herpes simplex virus 1 HSV-1", "herpes simplex virus HSV-1", "herpes simplex virus type 1 HSV-1", "herpes simplex virus type 1 HSV1", "herpes simplex virus type-1 HSV-1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Herpes simplex virus 1", "Human herpesvirus 1" ; a owl:Class ; rdfs:label "Human alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_10294 . obo:NCBITaxon_10310 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "HSV2" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Herpes simplex virus (type 2)", "Herpes simplex virus II", "Herpes simplex virus type 2", "Herpes simplex virus type 2 (HSV-2)", "Human herpesvirus 2" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Herpes simplex virus 2", "herpes simplex virus type 2 HSV-2" ; a owl:Class ; rdfs:label "Human alphaherpesvirus 2" ; rdfs:subClassOf obo:NCBITaxon_10294 . obo:NCBITaxon_10319 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Varicellovirus" ; rdfs:subClassOf obo:NCBITaxon_10293 . obo:NCBITaxon_10320 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:11265", "NCBITaxon:12738" ; oboInOwl:hasBroadSynonym "BoHV-1" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Bovine herpesvirus 1", "Bovine herpesvirus type 1", "Bovine herpesvirus-1", "Bovine rhinotracheitis virus", "bovine herpesvirus 1 BHV 1", "bovine herpesvirus 1 BHV-1", "bovine herpesvirus 1 BHV1", "bovine herpesvirus BHV-1", "bovine herpesvirus type 1 BHV-1", "bovine herpesvirus type-1 BHV-1", "infectious bovine rhinotracheitis virus BHV-1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Infectious bovine rhinotracheitis virus" ; a owl:Class ; rdfs:label "Bovine alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_10319 . obo:NCBITaxon_10326 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "EHV-1" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Equid herpesvirus 1", "Equine herpesvirus 1", "Equine herpesvirus type 1", "Equine herpesvirus-1", "equine abortion virus", "equine herpesvirus 1 EHV-1", "equine herpesvirus type-1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "equine herpesvirus type 1 EHV-1" ; a owl:Class ; rdfs:label "Equid alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_10319 . obo:NCBITaxon_10334 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Felid herpesvirus 1", "Feline alphaherpesvirus 1", "Feline herpesvirus 1", "Feline herpesvirus type 1", "feline herpesvirus", "feline herpesvirus type 1 FHV-1", "feline herpesvirus-1", "feline herpesvirus-1 FHV-1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Felid alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_10319 . obo:NCBITaxon_10335 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "HHV-3", "VZV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human herpes virus 3", "Human herpesvirus 3", "Varicella Zoster Virus", "Varicella-zoster virus", "varicella zoster virus VZV", "varicella-zoster virus VZV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Human alphaherpesvirus 3" ; rdfs:subClassOf obo:NCBITaxon_10319 . obo:NCBITaxon_10345 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:44156" ; oboInOwl:hasBroadSynonym "PRV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Alphaherpesvirus pseudorabies virus PRV", "Aujeszky's disease virus", "Pseudorabies Virus PRV", "Pseudorabies virus", "Suid herpesvirus 1", "Suid herpesvirus type 1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Suid alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_10319 . obo:NCBITaxon_10357 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Betaherpesviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Betaherpesvirinae" ; rdfs:subClassOf obo:NCBITaxon_3044472 . obo:NCBITaxon_10359 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "HHV-5" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human cytomegalovirus", "Human herpesvirus 5", "human herpesvirus type 5" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Human betaherpesvirus 5" ; rdfs:subClassOf obo:NCBITaxon_10357 . obo:NCBITaxon_10366 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Mouse cytomegalovirus 1", "Murid herpesvirus 1", "Murine cytomegalovirus", "murine cytomegalovirus (MCMV)", "murine cytomegalovirus MCMV", "murine herpesvirus 1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Murid betaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_10357 . obo:NCBITaxon_10386 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:10342", "NCBITaxon:12743", "NCBITaxon:46620" ; oboInOwl:hasBroadSynonym "GaHV-1", "ILTV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avian infectious laryngotracheitis virus", "Gallid herpesvirus 1", "Gallid herpesvirus type 1", "Laryngotracheitis virus", "infectious laryngotracheitis virus ILTV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Infectious laryngotracheitis virus" ; a owl:Class ; rdfs:label "Gallid alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_180255 . obo:NCBITaxon_10390 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:38013", "NCBITaxon:39111", "NCBITaxon:43684" ; oboInOwl:hasBroadSynonym "GaHV-2", "MDV1" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Gallid herpesvirus 2", "Gallid herpesvirus type 2", "Marek disease virus", "Marek disease virus type 1", "Marek's disease herpesvirus", "Marek's disease herpesvirus 1", "Marek's disease virus", "Marek's disease virus (MDV)", "Marek's disease virus MDV", "Marek's disease virus MDV1", "Marek's disease virus serotype 1 MDV-1", "Marek's disease virus type 1 MDV1", "Mareks disease virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Marek's disease virus type 1" ; a owl:Class ; rdfs:label "Gallid alphaherpesvirus 2" ; rdfs:subClassOf obo:NCBITaxon_180252 . obo:NCBITaxon_10405 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "mammalian hepatitis B-type viruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthohepadnavirus" ; rdfs:subClassOf obo:NCBITaxon_2732514 . obo:NCBITaxon_10407 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "HBV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human hepatitis B virus", "hepatitis B virus (HBV)", "hepatitis B virus HBV", "hepatitis B virus, HBV", "human hepatitis B virus HBV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Hepatitis B virus" ; rdfs:subClassOf obo:NCBITaxon_10405 . obo:NCBITaxon_104388 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:72150" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Anatid Herpes virus-1", "Anatid herpesvirus 1", "Duck enteritis virus", "Duck plague virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Anatid alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_180252 . obo:NCBITaxon_10469 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Baculovirus", "Baculovirus sp." ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "unidentified baculovirus" ; rdfs:subClassOf obo:NCBITaxon_10239 . obo:NCBITaxon_10497 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "ASFV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "African swine fever virus ASF", "African swine fever virus ASFV", "African swine fever virus, ASFV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "African swine fever virus" ; rdfs:subClassOf obo:NCBITaxon_2732525 . obo:NCBITaxon_10508 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Adenoviridae" ; rdfs:subClassOf obo:NCBITaxon_2732005 . obo:NCBITaxon_10509 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mastadenovirus" ; rdfs:subClassOf obo:NCBITaxon_10508 . obo:NCBITaxon_10512 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasAlternativeId "NCBITaxon:12607" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Canine adenovirus type 1", "Canine adenovirus type 1 Cav-1", "Mastadenovirus c1", "Mastadenovirus can1", "canine adenovirus type 1 Can1", "dog adenovirus 1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canine adenovirus 1" ; rdfs:subClassOf obo:NCBITaxon_10537 . obo:NCBITaxon_10514 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Canine adenovirus type 2", "Canine adenovirus type 2 Cav-1", "Mastadenovirus c2", "Mastadenovirus can2", "dog adenovirus 2" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canine adenovirus 2" ; rdfs:subClassOf obo:NCBITaxon_10537 . obo:NCBITaxon_10535 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Adenovirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "unidentified adenovirus" ; rdfs:subClassOf obo:NCBITaxon_10509 . obo:NCBITaxon_10537 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Canine adenovirus", "Canine adenovirus A" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canine mastadenovirus A" ; rdfs:subClassOf obo:NCBITaxon_10509 . obo:NCBITaxon_10566 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human Papilloma Virus", "human papillomavirus HPV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Human papillomavirus" ; rdfs:subClassOf obo:NCBITaxon_333774 . obo:NCBITaxon_10571 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovine papillomavirus" ; rdfs:subClassOf obo:NCBITaxon_333774 . obo:NCBITaxon_107819 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Clostridium perfringens (type D)" ; a owl:Class ; rdfs:label "Clostridium perfringens D" ; rdfs:subClassOf obo:NCBITaxon_1502 . obo:NCBITaxon_10786 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "FPLV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Feline panleucopenia virus", "Feline panleukopaenia virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Feline panleukopenia virus" ; rdfs:subClassOf obo:NCBITaxon_3052707 . obo:NCBITaxon_10787 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Feline panleukopenia virus (strain 193)" ; rdfs:subClassOf obo:NCBITaxon_10786 . obo:NCBITaxon_10788 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "CPV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canine parvovirus" ; rdfs:subClassOf obo:NCBITaxon_3052707 . obo:NCBITaxon_10792 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "MEV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mink enteritis virus" ; rdfs:subClassOf obo:NCBITaxon_10786 . obo:NCBITaxon_10796 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "PPV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "porcine parvovirus PPV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Porcine parvovirus" ; rdfs:subClassOf obo:NCBITaxon_1506574 . obo:NCBITaxon_10892 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Orbiviridae", "Orbiviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orbivirus" ; rdfs:subClassOf obo:NCBITaxon_2946186 . obo:NCBITaxon_10912 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Rotaviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rotavirus" ; rdfs:subClassOf obo:NCBITaxon_2946186 . obo:NCBITaxon_10913 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Porcine rotavirus" ; rdfs:subClassOf obo:NCBITaxon_10912 . obo:NCBITaxon_10927 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "bovine rotavirus BRV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovine rotavirus" ; rdfs:subClassOf obo:NCBITaxon_10912 . obo:NCBITaxon_10937 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Equine rotavirus" ; rdfs:subClassOf obo:NCBITaxon_10912 . obo:NCBITaxon_10993 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Birnaviridae" ; rdfs:subClassOf obo:NCBITaxon_2732396 . obo:NCBITaxon_10995 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:12740" ; oboInOwl:hasBroadSynonym "IBDV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avian infectious bursal disease virus", "Gumboro virus", "Infectious bursal disease virus of chickens", "infectious bursal disease virus IBDV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Infectious bursal disease virus" ; rdfs:subClassOf obo:NCBITaxon_10993 . obo:NCBITaxon_11002 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:12744" ; oboInOwl:hasBroadSynonym "IPNV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "infectious pancreatic necrosis virus IPNV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Infectious pancreatic necrosis virus" ; rdfs:subClassOf obo:NCBITaxon_10993 . obo:NCBITaxon_11019 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Alphaviridae", "arboviruses group A" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Alphavirus" ; rdfs:subClassOf obo:NCBITaxon_2732461 . obo:NCBITaxon_11021 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Eastern equine encephalomyelitis virus", "eastern equine encephalomyelitis EEE", "eastern equine encephalomyelitis virus EEEV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Eastern equine encephalitis virus" ; rdfs:subClassOf obo:NCBITaxon_11019 . obo:NCBITaxon_11034 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Sindbis virus" ; rdfs:subClassOf obo:NCBITaxon_11019 . obo:NCBITaxon_11036 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "VEE", "VEEV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Venezuelan equine encephalitis VEE", "Venezuelan equine encephalitis virus VEE", "Venezuelan equine encephalomyelitis virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Venezuelan equine encephalitis virus" ; rdfs:subClassOf obo:NCBITaxon_11019 . obo:NCBITaxon_11039 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Western equine encephalomyelitis virus" ; a owl:Class ; rdfs:label "Western equine encephalitis virus" ; rdfs:subClassOf obo:NCBITaxon_11019 . obo:NCBITaxon_11040 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rubivirus" ; rdfs:subClassOf obo:NCBITaxon_2732543 . obo:NCBITaxon_11041 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rubella virus" ; rdfs:subClassOf obo:NCBITaxon_11040 . obo:NCBITaxon_11047 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "EAV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Equine arteritis virus" ; rdfs:subClassOf obo:NCBITaxon_76803 . obo:NCBITaxon_11050 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Flavivirus (arbovirus group B)" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Flaviviridae" ; rdfs:subClassOf obo:NCBITaxon_2732406 . obo:NCBITaxon_11051 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "arboviruses group B" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Flavivirus" ; rdfs:subClassOf obo:NCBITaxon_11050 . obo:NCBITaxon_11072 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Japanese encephalitis (JE) virus", "Japanese encephalitis virus JE", "Japanese encephalitis virus JEV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Japanese encephalitis virus" ; rdfs:subClassOf obo:NCBITaxon_3044782 . obo:NCBITaxon_11082 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "WNV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "West Nile virus" ; rdfs:subClassOf obo:NCBITaxon_3044782 . obo:NCBITaxon_11084 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "TBEV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "FSME virus", "Tick born encephalitis virus", "tick-borne encephalitis virus TBE virus", "tick-borne encephalitis virus TBEV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Tick-borne encephalitis virus" ; rdfs:subClassOf obo:NCBITaxon_3044782 . obo:NCBITaxon_11089 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "YFV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Flavivirus febricis", "yellow fever virus YFV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Yellow fever virus" ; rdfs:subClassOf obo:NCBITaxon_3044782 . obo:NCBITaxon_11095 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1", "PMID:12832207", "PMID:7747470" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Pestivirus" ; rdfs:subClassOf obo:NCBITaxon_11050 . obo:NCBITaxon_11096 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:12625", "NCBITaxon:54314" ; oboInOwl:hasDbXref "GC_ID:1", "PMID:7747470" ; oboInOwl:hasExactSynonym "Hog cholera virus", "Pestivirus type 2", "classical swine fever virus CSFV", "swine fever virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Classical swine fever virus" ; rdfs:subClassOf obo:NCBITaxon_11095 . obo:NCBITaxon_11099 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:121864" ; oboInOwl:hasBroadSynonym "BVDV", "BVDV-1" ; oboInOwl:hasDbXref "GC_ID:1", "PMID:7747470" ; oboInOwl:hasExactSynonym "Bovine viral diarrhea virus", "Bovine viral diarrhea virus type 1", "Bovine viral diarrhea virus-1", "Mucosal disease virus", "Pestivirus type 1", "bovine viral diarrhea virus BVDV", "bovine viral diarrhea virus type I" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovine viral diarrhea virus 1" ; rdfs:subClassOf obo:NCBITaxon_11095 . obo:NCBITaxon_111105 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11411686", "PMID:28066339" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Porphyromonas gulae" ; rdfs:subClassOf obo:NCBITaxon_836 . obo:NCBITaxon_11118 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Coronaviridae" ; rdfs:subClassOf obo:NCBITaxon_76804 . obo:NCBITaxon_11120 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "IBV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avian infectious bronchitis virus", "avian infectious bronchitis coronavirus IBV", "avian infectious bronchitis virus IBV", "avian infectious bronchitis virus, IBV", "infectious bronchitis virus IBV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Infectious bronchitis virus" ; rdfs:subClassOf obo:NCBITaxon_2501931 . obo:NCBITaxon_11128 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "BCV", "BECV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Bovine enteritic coronavirus", "Bovine enteritic coronavirus BECV", "bovine coronavirus BCV", "bovine enteric coronavirus", "calf diarrheal coronavirus", "neonatal calf diarrhea virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovine coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . obo:NCBITaxon_11135 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "FIPV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Feline infectious peritonitis virus" ; rdfs:subClassOf obo:NCBITaxon_693997 . obo:NCBITaxon_11149 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:12859" ; oboInOwl:hasBroadSynonym "TGEV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Porcine transmissable gastroenteritis coronavirus", "Porcine transmissible gastroenteritis coronavirus", "porcine transmissible gastroenteritis virus", "transmissible gastroenteritis coronavirus", "transmissible gastroenteritis virus TGEV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Transmissible gastroenteritis virus" ; rdfs:subClassOf obo:NCBITaxon_693997 . obo:NCBITaxon_11153 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Canine enteric coronavirus", "canine coronavirus CCV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canine coronavirus" ; rdfs:subClassOf obo:NCBITaxon_693997 . obo:NCBITaxon_11157 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "negative-sense genome single-stranded RNA viruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mononegavirales" ; rdfs:subClassOf obo:NCBITaxon_2497569 . obo:NCBITaxon_11158 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Paramyxoviridae" ; rdfs:subClassOf obo:NCBITaxon_11157 . obo:NCBITaxon_11229 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Morbilliviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Morbillivirus" ; rdfs:subClassOf obo:NCBITaxon_2560076 . obo:NCBITaxon_11234 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:11230" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Cell-associated subacute sclerosing panencephalitis", "Measles virus", "Subacute sclerosing panencephalitis virus", "measles virus MV", "rougeole virus", "rubeola virus", "subacute sclerose panencephalitis virus", "subacute sclerosing panencephalitis virus, SSPEV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Measles morbillivirus" ; rdfs:subClassOf obo:NCBITaxon_11229 . obo:NCBITaxon_11241 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "RDV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Rinderpest virus", "rinderpest virus RPV", "rinderpest virus RV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rinderpest morbillivirus" ; rdfs:subClassOf obo:NCBITaxon_11229 . obo:NCBITaxon_11244 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Pneumovirinae" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Pneumoviridae" ; rdfs:subClassOf obo:NCBITaxon_11157 . obo:NCBITaxon_11246 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:12604" ; oboInOwl:hasBroadSynonym "BRS", "BRSV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Bovine respiratory syncytial virus", "bovine RSV", "bovine respiratory syncytial virus BRSV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovine orthopneumovirus" ; rdfs:subClassOf obo:NCBITaxon_1868215 . obo:NCBITaxon_11250 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "HRSV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human respiratory syncytial virus", "human RSV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Human orthopneumovirus" ; rdfs:subClassOf obo:NCBITaxon_1868215 . obo:NCBITaxon_11266 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasAlternativeId "NCBITaxon:11267" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Filovirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Filoviridae" ; rdfs:subClassOf obo:NCBITaxon_11157 . obo:NCBITaxon_11270 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1", "PMID:16186241" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rhabdoviridae" ; rdfs:subClassOf obo:NCBITaxon_11157 . obo:NCBITaxon_11286 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Lyssavirus" ; rdfs:subClassOf obo:NCBITaxon_11270 . obo:NCBITaxon_11287 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:12873", "NCBITaxon:12874" ; oboInOwl:hasBroadSynonym "VHSV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Haemorrhagic septicemia virus", "Hemorrhagic septicemia virus", "Viral haemorrhagic septicaemia virus", "hemorragic septicemy virus of fish", "viral haemorrhagic scepticaemia virus VHS", "viral haemorrhagic septicaemia virus VHSV", "viral hemorrhagic septicemia virus VHSV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Viral hemorrhagic septicemia virus" ; rdfs:subClassOf obo:NCBITaxon_186778 . obo:NCBITaxon_11290 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "IHNV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Infectious hematopoietic necrosis virus" ; rdfs:subClassOf obo:NCBITaxon_186778 . obo:NCBITaxon_11292 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Rabies lyssavirus", "Rabies virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Lyssavirus rabies" ; rdfs:subClassOf obo:NCBITaxon_11286 . obo:NCBITaxon_11308 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthomyxoviridae" ; rdfs:subClassOf obo:NCBITaxon_2497571 . obo:NCBITaxon_11309 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Influenza virus", "Influenza virus sp.", "Influenzavirus", "avian influenza virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "unidentified influenza virus" ; rdfs:subClassOf obo:NCBITaxon_35324 . obo:NCBITaxon_11318 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Dhori thogotovirus", "Dhori virus", "Tick-borne virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Thogotovirus dhoriense" ; rdfs:subClassOf obo:NCBITaxon_11308 . obo:NCBITaxon_11320 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "FLUAV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human Influenza A Virus", "Influenza virus type A", "influenza A virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Influenza A virus" ; rdfs:subClassOf obo:NCBITaxon_197911 . obo:NCBITaxon_114727 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "H1N1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "H1N1 subtype" ; rdfs:subClassOf obo:NCBITaxon_11320 . obo:NCBITaxon_11588 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "RVFV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rift Valley fever virus" ; rdfs:subClassOf obo:NCBITaxon_1980410 . obo:NCBITaxon_11636 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11835", "NCBITaxon:11872", "NCBITaxon:36380" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avian reticuloendotheliosis virus", "reticuloendotheliosis virus A REV-A", "reticuloendotheliosis virus REV-A" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Reticuloendotheliosis virus" ; rdfs:subClassOf obo:NCBITaxon_153135 . obo:NCBITaxon_11646 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Lentivirinae" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Lentivirus" ; rdfs:subClassOf obo:NCBITaxon_327045 . obo:NCBITaxon_11673 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "FIV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "feline immunodeficiency virus FIV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Feline immunodeficiency virus" ; rdfs:subClassOf obo:NCBITaxon_11646 . obo:NCBITaxon_11723 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11677", "NCBITaxon:11739", "NCBITaxon:11740" ; oboInOwl:hasBroadSynonym "CIV", "SIV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Chimpanzee immunodeficiency virus", "Chimpanzee immunodeficiency virus (SIV(CPZ))", "Simian immunodeficiency virus SIVcpz", "simian immunodeficiency virus SIV", "simian immunodeficiency virus, SIV", "simian immunodeficiency viruses SIV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Simian immunodeficiency virus" ; rdfs:subClassOf obo:NCBITaxon_11646 . obo:NCBITaxon_117565 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "fish", "fishes" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Agnatha", "Hyperotreti" ; a owl:Class ; rdfs:label "Myxini" ; rdfs:subClassOf obo:NCBITaxon_7742 . obo:NCBITaxon_117571 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasAlternativeId "NCBITaxon:40673" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "bony vertebrates" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Euteleostomi" ; rdfs:subClassOf obo:NCBITaxon_7742 . obo:NCBITaxon_11768 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11920" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Feline leukemia provirus", "feline leukemia virus FeLV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Feline leukemia virus" ; rdfs:subClassOf obo:NCBITaxon_153135 . obo:NCBITaxon_11901 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "BLV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "bovine leukemia virus BLV", "bovine leukemia virus, BLV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovine leukemia virus" ; rdfs:subClassOf obo:NCBITaxon_327045 . obo:NCBITaxon_119088 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Enoplea" ; rdfs:subClassOf obo:NCBITaxon_1206794 . obo:NCBITaxon_11974 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Caliciviridae" ; rdfs:subClassOf obo:NCBITaxon_464095 . obo:NCBITaxon_11976 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:12806", "NCBITaxon:31701" ; oboInOwl:hasBroadSynonym "RHDV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Rabbit haemorrhagic disease virus", "rabbit hemorrhagic disease virus RHDV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rabbit hemorrhagic disease virus" ; rdfs:subClassOf obo:NCBITaxon_11974 . obo:NCBITaxon_11978 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "FCV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Feline vesivirus", "feline calicivirus FCV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Feline calicivirus" ; rdfs:subClassOf obo:NCBITaxon_11974 . obo:NCBITaxon_12058 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Picornavirus" ; a owl:Class ; rdfs:label "Picornaviridae" ; rdfs:subClassOf obo:NCBITaxon_464095 . obo:NCBITaxon_12059 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:12128" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Enteroviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Enterovirus" ; rdfs:subClassOf obo:NCBITaxon_12058 . obo:NCBITaxon_12066 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Coxsackievirus" ; rdfs:subClassOf obo:NCBITaxon_12059 . obo:NCBITaxon_1206794 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Ecdysozoa" ; rdfs:subClassOf obo:NCBITaxon_33317 . obo:NCBITaxon_12080 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasBroadSynonym "HPV-1", "PV1" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human poliovirus 1", "Human poliovirus type 1", "Polio virus 1", "Poliovirus type 1", "poliovirus type 1 PV1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Poliovirus 1" ; rdfs:subClassOf obo:NCBITaxon_138950 . obo:NCBITaxon_12083 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasBroadSynonym "HPV-2" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human Poliovirus type 2", "Human poliovirus 2", "Poliovirus type 2" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Poliovirus 2" ; rdfs:subClassOf obo:NCBITaxon_138950 . obo:NCBITaxon_12086 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasBroadSynonym "HPV-3" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human poliovirus 3", "Human poliovirus type 3", "Polio virus 3" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Poliovirus serotype 3", "Poliovirus type 3" ; a owl:Class ; rdfs:label "Poliovirus 3" ; rdfs:subClassOf obo:NCBITaxon_138950 . obo:NCBITaxon_12091 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Hepatovirus" ; rdfs:subClassOf obo:NCBITaxon_2946633 . obo:NCBITaxon_12092 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "HAV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Hepatitis A virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Hepatovirus A" ; rdfs:subClassOf obo:NCBITaxon_12091 . obo:NCBITaxon_12110 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "FMDV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Foot and mouth disease virus", "foot and mouth disease virus FMDV", "foot-and-mouth disease virus FMDV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Foot-and-mouth disease virus" ; rdfs:subClassOf obo:NCBITaxon_12058 . obo:NCBITaxon_1224 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_phylum ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11321122", "PMID:11837318" ; oboInOwl:hasExactSynonym "purple photosynthetic bacteria and relatives" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "\"Alphaproteobacteriota\" Whitman et al. 2018", "Alphaproteobacteriota", "Proteobacteria", "Proteobacteriota", "proteobacteria" ; a owl:Class ; rdfs:label "Pseudomonadota" ; rdfs:subClassOf obo:NCBITaxon_2 . obo:NCBITaxon_1236 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:11", "PMID:23334881" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Proteobacteria gamma subdivision", "Pseudomonadia", "Purple bacteria, gamma subdivision", "g-proteobacteria", "gamma proteobacteria", "gamma subdivision", "gamma subgroup" ; a owl:Class ; rdfs:label "Gammaproteobacteria" ; rdfs:subClassOf obo:NCBITaxon_1224 . obo:NCBITaxon_1238 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1371057" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Piscirickettsia salmonis" ; rdfs:subClassOf obo:NCBITaxon_72273 . obo:NCBITaxon_1239 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_phylum ; oboInOwl:hasAlternativeId "NCBITaxon:31968" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10555317", "PMID:11034484", "PMID:11542017", "PMID:15143038", "PMID:25403554", "PMID:37409558" ; oboInOwl:hasExactSynonym "Firmicutes", "low G+C Gram-positive bacteria", "low GC Gram+" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "\"Firmicutes\" corrig. Gibbons and Murray 1978 (Approved Lists 1980)", "Bacillaeota", "Bacillota corrig. Gibbons and Murray 2021", "Bacillus/Clostridium group", "Clostridium group firmicutes", "Firmicuteota", "Low G+C firmicutes", "clostridial firmicutes", "firmicutes" ; a owl:Class ; rdfs:label "Bacillota" ; rdfs:subClassOf obo:NCBITaxon_1783272 . obo:NCBITaxon_12455 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "BDV" ; oboInOwl:hasDbXref "GC_ID:1", "PMID:25449305" ; oboInOwl:hasExactSynonym "Borna disease virus BDV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Borna disease virus" ; rdfs:subClassOf obo:NCBITaxon_11157 . obo:NCBITaxon_12475 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:12682" ; oboInOwl:hasBroadSynonym "HDV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Hepatitis D virus", "hepatitis delta virus HDV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Hepatitis delta virus" ; rdfs:subClassOf obo:NCBITaxon_10239 . obo:NCBITaxon_12618 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "CAV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Chicken infectious anemia virus", "chicken anaemia agent CAA", "chicken anemia virus CAV", "chicken anemia virus, CAV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "chicken anaemia agent virus CAA" ; a owl:Class ; rdfs:label "Chicken anemia virus" ; rdfs:subClassOf obo:NCBITaxon_10239 . obo:NCBITaxon_12637 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Dengue virus" ; rdfs:subClassOf obo:NCBITaxon_3044782 . obo:NCBITaxon_12721 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "HIV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "AIDS virus" ; a owl:Class ; rdfs:label "Human immunodeficiency virus" ; rdfs:subClassOf obo:NCBITaxon_11646 . obo:NCBITaxon_1279 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319469", "PMID:10319495", "PMID:10425778", "PMID:10758876", "PMID:12656157", "PMID:17220435", "PMID:9734063" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Aurococcus" ; a owl:Class ; rdfs:label "Staphylococcus" ; rdfs:subClassOf obo:NCBITaxon_1385 . obo:NCBITaxon_1280 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:325213", "NCBITaxon:46170", "NCBITaxon:72759" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:31023808", "PMID:8573498" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Micrococcus aureus", "Micrococcus pyogenes", "Staphlococcus pyogenes citreus", "Staphylococcus aureus subsp. anaerobius", "Staphylococcus pyogenes aureus" ; a owl:Class ; rdfs:label "Staphylococcus aureus" ; rdfs:subClassOf obo:NCBITaxon_1279 . obo:NCBITaxon_12814 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "RSV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "respiratory syncytial virus RS", "respiratory syncytial virus RS virus", "respiratory syncytial virus RSV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Respiratory syncytial virus" ; rdfs:subClassOf obo:NCBITaxon_11246 . obo:NCBITaxon_12845 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Swine influenza virus" ; rdfs:subClassOf obo:NCBITaxon_35324 . obo:NCBITaxon_1301 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10555340", "PMID:14657115", "PMID:1720654", "PMID:19620365", "PMID:19880633", "PMID:7537076", "PMID:8995803" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Streptococcus" ; rdfs:subClassOf obo:NCBITaxon_91061 . obo:NCBITaxon_1307 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:23245487", "PMID:5220563", "PMID:9731300", "PMID:9734065" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Streptococcus suis" ; rdfs:subClassOf obo:NCBITaxon_1301 . obo:NCBITaxon_1311 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:76757" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:15774692", "PMID:8995807" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Streptoccocus de la mammite", "Streptococcus agalactiae contagiosae", "Streptococcus difficile", "Streptococcus difficilis", "Streptococcus mastitidis" ; a owl:Class ; rdfs:label "Streptococcus agalactiae" ; rdfs:subClassOf obo:NCBITaxon_1301 . obo:NCBITaxon_1313 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Diplococcus pneumoniae", "Micrococcus pneumoniae" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae" ; rdfs:subClassOf obo:NCBITaxon_1301 . obo:NCBITaxon_1314 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Micrococcus scarlatinae", "Streptococcus erysipelatos", "Streptococcus hemolyticus", "Streptococcus scarlatinae" ; a owl:Class ; rdfs:label "Streptococcus pyogenes" ; rdfs:subClassOf obo:NCBITaxon_1301 . obo:NCBITaxon_1335626 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "MERS", "MERS-CoV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "MERS coronavirus", "MERS virus", "Middle East Respiratory Syndrome Coronavirus (MERS-CoV)", "Middle East respiratory syndrome coronavirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Middle East respiratory syndrome-related coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . obo:NCBITaxon_1336 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Streptococcus equi" ; rdfs:subClassOf obo:NCBITaxon_1301 . obo:NCBITaxon_13488 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Dicentrarchus" ; rdfs:subClassOf obo:NCBITaxon_1489388 . obo:NCBITaxon_13489 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "European sea bass", "European seabass" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Labrax labrax", "Morone labrax", "Perca labrax", "Roccus labrax", "Sciaena labrax" ; a owl:Class ; rdfs:label "Dicentrarchus labrax" ; rdfs:subClassOf obo:NCBITaxon_13488 . obo:NCBITaxon_136 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11075904", "PMID:11542017", "PMID:16558735", "PMID:1917844", "PMID:23908650" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "spirochetes" ; a owl:Class ; rdfs:label "Spirochaetales" ; rdfs:subClassOf obo:NCBITaxon_203692 . obo:NCBITaxon_1385 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasAlternativeId "NCBITaxon:2954866" ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus/Staphylococcus group", "Caryophanales" ; a owl:Class ; rdfs:label "Bacillales" ; rdfs:subClassOf obo:NCBITaxon_91061 . obo:NCBITaxon_1386 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10843090", "PMID:11491334", "PMID:1742196", "PMID:2223602", "PMID:23475340", "PMID:7727277", "PMID:8138135", "PMID:8863420" ; oboInOwl:hasExactSynonym "Bacillus", "Bacillus rRNA group 1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bacillus " ; rdfs:subClassOf obo:NCBITaxon_1385 . obo:NCBITaxon_138950 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:138953" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Enterovirus EV-C", "Human enterovirus C", "Poliovirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Enterovirus C" ; rdfs:subClassOf obo:NCBITaxon_12059 . obo:NCBITaxon_139 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1380285", "PMID:1503971", "PMID:24744012", "PMID:7699027", "PMID:7981102", "PMID:8995796", "PMID:9336916" ; oboInOwl:hasExactSynonym "Lyme disease spirochete" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Borrelia burgdorferi" ; a owl:Class ; rdfs:label "Borreliella burgdorferi" ; rdfs:subClassOf obo:NCBITaxon_64895 . obo:NCBITaxon_1392 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1494525", "NCBITaxon:1494531", "NCBITaxon:1494577" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:8123566" ; oboInOwl:hasExactSynonym "anthrax", "anthrax bacterium" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus cereus var. anthracis", "Bacteridium anthracis" ; a owl:Class ; rdfs:label "Bacillus anthracis" ; rdfs:subClassOf obo:NCBITaxon_1386 . obo:NCBITaxon_1437010 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1", "PMID:11743200", "PMID:11791233" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Boreotheria" ; a owl:Class ; rdfs:label "Boreoeutheria" ; rdfs:subClassOf obo:NCBITaxon_40674 . obo:NCBITaxon_1485 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:69207" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:26643615", "PMID:27488356" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Anaerobacter" ; a owl:Class ; rdfs:label "Clostridium" ; rdfs:subClassOf obo:NCBITaxon_1239 . obo:NCBITaxon_1489388 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_cohort ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Euteleosteomorpha" ; rdfs:subClassOf obo:NCBITaxon_186625 . obo:NCBITaxon_1491 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:29368" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10028279", "PMID:15244052" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus botulinus", "Bacillus putrificus", "Botulobacillus botulinus", "Clostridium putrificum", "Ermengemillus botulinus", "Pacinia putrifica" ; a owl:Class ; rdfs:label "Clostridium botulinum" ; rdfs:subClassOf obo:NCBITaxon_1485 . obo:NCBITaxon_149539 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:2588446", "NCBITaxon:2588447", "NCBITaxon:41533", "NCBITaxon:592" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10758910" ; oboInOwl:hasExactSynonym "Salmonella enterica serovar Enteritidis" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus enteritidis", "Salmonella enteritidis" ; a owl:Class ; rdfs:label "Salmonella enterica subsp. enterica serovar Enteritidis" ; rdfs:subClassOf obo:NCBITaxon_59201 . obo:NCBITaxon_149595 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canine parainfluenza virus" ; rdfs:subClassOf obo:NCBITaxon_11158 . obo:NCBITaxon_150052 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subspecies ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11043982" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Yersinia enterocolitica subsp. enterocolitica" ; rdfs:subClassOf obo:NCBITaxon_629 . obo:NCBITaxon_1502 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1683536" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1374625", "PMID:184898" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "'Clostridium plagarum'", "Bacillus perfringens", "Bacterium welchii", "Clostridium plagarum" ; a owl:Class ; rdfs:label "Clostridium perfringens" ; rdfs:subClassOf obo:NCBITaxon_1485 . obo:NCBITaxon_1506574 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:10781" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Parvovirus", "Parvoviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Protoparvovirus" ; rdfs:subClassOf obo:NCBITaxon_40119 . obo:NCBITaxon_1513 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus tetani" ; a owl:Class ; rdfs:label "Clostridium tetani" ; rdfs:subClassOf obo:NCBITaxon_1485 . obo:NCBITaxon_151340 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1", "PMID:20206957" ; oboInOwl:hasExactSynonym "Papillomavirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Papillomaviridae" ; rdfs:subClassOf obo:NCBITaxon_2732421 . obo:NCBITaxon_151341 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Polyomaviridae" ; rdfs:subClassOf obo:NCBITaxon_2732421 . obo:NCBITaxon_153135 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:11762" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "MLV-related viruses", "Mammalian type C retrovirus group", "Mammalian type C retroviruses", "mammalian type C oncoviruses", "type C oncoviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Gammaretrovirus" ; rdfs:subClassOf obo:NCBITaxon_327045 . obo:NCBITaxon_1549675 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superorder ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Galloanseri", "ducks, geese, chickens, fowl, quail, currasows and allies" ; a owl:Class ; rdfs:label "Galloanserae" ; rdfs:subClassOf obo:NCBITaxon_8825 . obo:NCBITaxon_160 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Microspironema pallidum", "Spirillum pallidum", "Spirochaeta pallida", "Spironema pallidum" ; a owl:Class ; rdfs:label "Treponema pallidum" ; rdfs:subClassOf obo:NCBITaxon_136 . obo:NCBITaxon_162145 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "HMPV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Human metapneumovirus" ; rdfs:subClassOf obo:NCBITaxon_162387 . obo:NCBITaxon_162387 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Metapneumovirus" ; rdfs:subClassOf obo:NCBITaxon_11244 . obo:NCBITaxon_1639 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1634566", "NCBITaxon:2293539", "NCBITaxon:2293540", "NCBITaxon:2293541", "NCBITaxon:2293542", "NCBITaxon:2293543", "NCBITaxon:2293544", "NCBITaxon:2293545", "NCBITaxon:2293546", "NCBITaxon:2293547", "NCBITaxon:2364651", "NCBITaxon:2364652", "NCBITaxon:2364653", "NCBITaxon:2364654", "NCBITaxon:2364655", "NCBITaxon:2364656", "NCBITaxon:2364657", "NCBITaxon:2364658", "NCBITaxon:2364659", "NCBITaxon:2364660", "NCBITaxon:2482733", "NCBITaxon:2482734", "NCBITaxon:2482735", "NCBITaxon:2482736", "NCBITaxon:2482737", "NCBITaxon:2482738", "NCBITaxon:2482739", "NCBITaxon:2482740", "NCBITaxon:2482741", "NCBITaxon:2482742", "NCBITaxon:2482743", "NCBITaxon:2482744", "NCBITaxon:2482745", "NCBITaxon:2482746", "NCBITaxon:2482747", "NCBITaxon:2482748", "NCBITaxon:2482749", "NCBITaxon:2484857", "NCBITaxon:2484858", "NCBITaxon:2485082", "NCBITaxon:2485083", "NCBITaxon:2485084", "NCBITaxon:2485085", "NCBITaxon:2485086", "NCBITaxon:2485087", "NCBITaxon:2485088", "NCBITaxon:2485089", "NCBITaxon:2485090", "NCBITaxon:2485091", "NCBITaxon:2485092", "NCBITaxon:2485093", "NCBITaxon:2485094", "NCBITaxon:2485095", "NCBITaxon:2485096", "NCBITaxon:2486732", "NCBITaxon:2486733", "NCBITaxon:2486734", "NCBITaxon:2486735", "NCBITaxon:2486736", "NCBITaxon:2486737", "NCBITaxon:2486738", "NCBITaxon:2486739", "NCBITaxon:2486740", "NCBITaxon:2486741" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:17773427", "PMID:1906732", "PMID:8782698" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacterium monocytogenes", "Bacterium monocytogenes hominis", "Corynebacterium infantisepticum", "Corynebacterium parvulum", "Erysipelothrix monocytogenes", "Listerella hepatolytica" ; a owl:Class ; rdfs:label "Listeria monocytogenes" ; rdfs:subClassOf obo:NCBITaxon_1385 . obo:NCBITaxon_1648 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1503975", "PMID:8427802" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus insidiosus", "Bacillus rhusiopathiae suis", "Bacterium rhusiopathiae", "Erysipelothrix erysipeloides", "Erysipelothrix insidiosa", "Erysipelothrix murisepticus", "Erysipelothrix porci" ; a owl:Class ; rdfs:label "Erysipelothrix rhusiopathiae" ; rdfs:subClassOf obo:NCBITaxon_1239 . obo:NCBITaxon_1649845 obo:IAO_0000412 ; ncbitaxon:has_rank ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Yersinia pseudotuberculosis complex" ; rdfs:subClassOf obo:NCBITaxon_629 . obo:NCBITaxon_1653394 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mammarenavirus" ; rdfs:subClassOf obo:NCBITaxon_1980410 . obo:NCBITaxon_1678143 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:12461", "NCBITaxon:2953663" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Orthohepevirus A" ; a owl:Class ; rdfs:label "Paslahepevirus balayani" ; rdfs:subClassOf obo:NCBITaxon_2732543 . obo:NCBITaxon_171 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:29512", "NCBITaxon:29514", "NCBITaxon:29516" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10425768", "PMID:1581182", "PMID:19868121", "PMID:9103653" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Leptospira" ; rdfs:subClassOf obo:NCBITaxon_203692 . obo:NCBITaxon_1716 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:144193" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10425754", "PMID:19661509", "PMID:29760685", "PMID:30186281", "PMID:7547284", "PMID:7547291", "PMID:7547293", "PMID:8186090" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Turicella" ; a owl:Class ; rdfs:label "Corynebacterium" ; rdfs:subClassOf obo:NCBITaxon_85007 . obo:NCBITaxon_1717 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:7729671" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus diphtheriae", "Bacterium diphtheriae", "Microsporon diphthericum", "Microsporon diphtheriticum", "Mycobacterium diphtheriae", "Pacinia loeffleri" ; a owl:Class ; rdfs:label "Corynebacterium diphtheriae" ; rdfs:subClassOf obo:NCBITaxon_1716 . obo:NCBITaxon_1719 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus pseudotuberculosis", "Bacillus pseudotuberculosis-ovis", "Corynebacterium ovis", "Corynebacterium preisz-nocardi", "Corynebacterium pseudotuberculosis-ovis", "Mycobacterium tuberculosis-ovis" ; a owl:Class ; rdfs:label "Corynebacterium pseudotuberculosis" ; rdfs:subClassOf obo:NCBITaxon_1716 . obo:NCBITaxon_173 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:2843297", "NCBITaxon:2843299" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:15545494", "PMID:19867994", "PMID:19868337", "PMID:19972157", "PMID:25288661", "PMID:9542090" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Leptospira icteroides", "Spirochaeta biflexa", "Spirochaeta icterogenes", "Spirochaeta icterohaemorrhagiae", "Spirochaeta interrogans", "Spirochaeta nodosa" ; a owl:Class ; rdfs:label "Leptospira interrogans" ; rdfs:subClassOf obo:NCBITaxon_171 . obo:NCBITaxon_175121 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Passeroidea" ; rdfs:subClassOf obo:NCBITaxon_8825 . obo:NCBITaxon_176 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Leptospira hardjo" ; a owl:Class ; rdfs:label "Leptospira interrogans serovar Hardjo" ; rdfs:subClassOf obo:NCBITaxon_173 . obo:NCBITaxon_1763 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1380284", "PMID:1581193", "PMID:16014496", "PMID:1883713", "PMID:2275850", "PMID:31296783", "PMID:31649146", "PMID:31649147", "PMID:34554081", "PMID:7547284", "PMID:7547304", "PMID:7907223", "PMID:8863452" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mycobacterium Lehmann and Neumann 1896 (Approved Lists 1980)" ; a owl:Class ; rdfs:label "Mycobacterium" ; rdfs:subClassOf obo:NCBITaxon_85007 . obo:NCBITaxon_1764 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:2397193", "PMID:8347508" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus tuberculosis gallinarum", "Mycobacterium tuberculosis avium", "Mycobacterium tuberculosis typus gallinaceus", "Tuberculose des oiseaux" ; a owl:Class ; rdfs:label "Mycobacterium avium" ; rdfs:subClassOf obo:NCBITaxon_1763 . obo:NCBITaxon_1765 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_biotype ; oboInOwl:hasAlternativeId "NCBITaxon:115863" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10618079", "PMID:11931153", "PMID:14657105", "PMID:29205127" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mycobacterium bovis", "Mycobacterium tuberculosis typus bovinus", "Mycobacterium tuberculosis var. bovis" ; a owl:Class ; rdfs:label "Mycobacterium tuberculosis variant bovis" ; rdfs:subClassOf obo:NCBITaxon_1773 . obo:NCBITaxon_1769 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus leprae" ; a owl:Class ; rdfs:label "Mycobacterium leprae" ; rdfs:subClassOf obo:NCBITaxon_1763 . obo:NCBITaxon_1773 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:2528440" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:29205127" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus tuberculosis", "Bacterium tuberculosis", "Mycobacterium tuberculosis typus humanus", "Mycobacterium tuberculosis var. hominis", "Mycobacterium tuberculosis variant tuberculosis" ; a owl:Class ; rdfs:label "Mycobacterium tuberculosis" ; rdfs:subClassOf obo:NCBITaxon_1763 . obo:NCBITaxon_1781 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:12089250", "PMID:20668542" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mycobacterium balnei", "Mycobacterium platypoecilus" ; a owl:Class ; rdfs:label "Mycobacterium marinum" ; rdfs:subClassOf obo:NCBITaxon_1763 . obo:NCBITaxon_1783272 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:11", "PMID:18988685", "PMID:23851394" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Terrabacteria group" ; rdfs:subClassOf obo:NCBITaxon_2 . obo:NCBITaxon_180252 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Marek's disease-like viruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mardivirus" ; rdfs:subClassOf obo:NCBITaxon_10293 . obo:NCBITaxon_180255 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Infectious laryngo-tracheitis-like viruses", "Infectious laryngotracheitis-like viruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Iltovirus" ; rdfs:subClassOf obo:NCBITaxon_10293 . obo:NCBITaxon_186537 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Marburg-like viruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Marburgvirus" ; rdfs:subClassOf obo:NCBITaxon_11266 . obo:NCBITaxon_186625 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Clupeocephala" ; rdfs:subClassOf obo:NCBITaxon_7898 . obo:NCBITaxon_186778 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Novirhabdovirus" ; rdfs:subClassOf obo:NCBITaxon_11270 . obo:NCBITaxon_1868215 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthopneumovirus" ; rdfs:subClassOf obo:NCBITaxon_11244 . obo:NCBITaxon_1891747 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:10625" ; oboInOwl:hasBroadSynonym "BFPyV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Aves polyomavirus 1", "BFDV", "Budgerigar fledgling disease polyomavirus", "Budgerigar fledgling disease virus", "Budgerigar fledgling polyomavirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Gammapolyomavirus avis" ; rdfs:subClassOf obo:NCBITaxon_151341 . obo:NCBITaxon_1903411 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:11", "PMID:27620848" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Yersiniaceae" ; rdfs:subClassOf obo:NCBITaxon_91347 . obo:NCBITaxon_194 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11542086", "PMID:12361288", "PMID:16627635", "PMID:1704793", "PMID:19801389", "PMID:29034857" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Campylobacter" ; rdfs:subClassOf obo:NCBITaxon_213849 . obo:NCBITaxon_196 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11321120", "PMID:1354478" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Spirillum fetus", "Vibrio fetus" ; a owl:Class ; rdfs:label "Campylobacter fetus" ; rdfs:subClassOf obo:NCBITaxon_194 . obo:NCBITaxon_197 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:2172531", "NCBITaxon:2182326", "NCBITaxon:2201165", "NCBITaxon:2211407", "NCBITaxon:2211408", "NCBITaxon:2211409", "NCBITaxon:2293848", "NCBITaxon:2293849", "NCBITaxon:2293850", "NCBITaxon:2303571", "NCBITaxon:2305452", "NCBITaxon:2305453", "NCBITaxon:2305454", "NCBITaxon:2305455", "NCBITaxon:2305456", "NCBITaxon:2305457", "NCBITaxon:2305458", "NCBITaxon:2305459", "NCBITaxon:2340789", "NCBITaxon:2478524", "NCBITaxon:2572055", "NCBITaxon:2572062", "NCBITaxon:2572070", "NCBITaxon:2572072", "NCBITaxon:2572075", "NCBITaxon:2572080", "NCBITaxon:2572086", "NCBITaxon:3042472", "NCBITaxon:3042475", "NCBITaxon:3042476", "NCBITaxon:3042477", "NCBITaxon:3042478", "NCBITaxon:3042479", "NCBITaxon:3042480", "NCBITaxon:3042481", "NCBITaxon:3042482", "NCBITaxon:3042483", "NCBITaxon:3042484", "NCBITaxon:3042485", "NCBITaxon:3042486", "NCBITaxon:3042488" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11321120" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Campylobacter fetus subsp. jejuni", "Vibrio hepaticus", "Vibrio jejuni" ; a owl:Class ; rdfs:label "Campylobacter jejuni" ; rdfs:subClassOf obo:NCBITaxon_194 . obo:NCBITaxon_197911 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Influenzavirus A" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Alphainfluenzavirus" ; rdfs:subClassOf obo:NCBITaxon_11308 . obo:NCBITaxon_197912 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Influenzavirus B" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Betainfluenzavirus" ; rdfs:subClassOf obo:NCBITaxon_11308 . obo:NCBITaxon_197913 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Influenzavirus C" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Gammainfluenzavirus" ; rdfs:subClassOf obo:NCBITaxon_11308 . obo:NCBITaxon_1980410 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bunyavirales" ; rdfs:subClassOf obo:NCBITaxon_2497571 . obo:NCBITaxon_1980442 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:11598" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Hantavirus" ; a owl:Class ; rdfs:label "Orthohantavirus" ; rdfs:subClassOf obo:NCBITaxon_1980410 . obo:NCBITaxon_1980915 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:38142" ; oboInOwl:hasBroadSynonym "HIRRV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Hirame novirhabdovirus", "Hirame rhabdovirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Novirhabdovirus hirame" ; rdfs:subClassOf obo:NCBITaxon_186778 . obo:NCBITaxon_2 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superkingdom ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10425795", "PMID:10425796", "PMID:10425797", "PMID:10490293", "PMID:10843050", "PMID:10939651", "PMID:10939673", "PMID:10939677", "PMID:11211268", "PMID:11321083", "PMID:11321113", "PMID:11411719", "PMID:11540071", "PMID:11542017", "PMID:11542087", "PMID:11760965", "PMID:12054223", "PMID:2112744", "PMID:270744", "PMID:32628106", "PMID:36748408", "PMID:7520741", "PMID:8123559", "PMID:8186100", "PMID:8590690", "PMID:9103655", "PMID:9336922" ; oboInOwl:hasExactSynonym "eubacteria" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Monera", "Procaryotae", "Prokaryota", "Prokaryotae", "bacteria", "prokaryote", "prokaryotes" ; a owl:Class ; rdfs:label "Bacteria" ; rdfs:subClassOf obo:OBI_0100026 . obo:NCBITaxon_200644 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Flavobacteriales" ; rdfs:subClassOf obo:NCBITaxon_976 . obo:NCBITaxon_203692 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11837318", "PMID:25288668", "PMID:26654112" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "\"Leptospiria\" Cavalier-Smith 2020", "Spirochaetes" ; a owl:Class ; rdfs:label "Spirochaetia" ; rdfs:subClassOf obo:NCBITaxon_2 . obo:NCBITaxon_204722 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11", "PMID:12271122" ; oboInOwl:hasExactSynonym "Brucella suis str. 1330" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Brucella melitensis biovar Suis str. 1330", "Brucella suis ATCC 23444", "Brucella suis NCTC 10316" ; a owl:Class ; rdfs:label "Brucella suis 1330" ; rdfs:subClassOf obo:NCBITaxon_29461 . obo:NCBITaxon_205488 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11268" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Ebola virus EBO", "unidentified Ebola virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Ebola virus sp." ; rdfs:subClassOf obo:NCBITaxon_11266 . obo:NCBITaxon_206351 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:11", "PMID:23575986" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Neisseriales" ; rdfs:subClassOf obo:NCBITaxon_28216 . obo:NCBITaxon_2092 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:4", "PMID:13403276", "PMID:16350067" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Borrelomycetaceae", "Parasitaceae", "Pleuropneumoniaceae" ; a owl:Class ; rdfs:label "Mycoplasmataceae" ; rdfs:subClassOf obo:NCBITaxon_544448 . obo:NCBITaxon_2093 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:29500", "NCBITaxon:57371" ; oboInOwl:hasDbXref "GC_ID:4", "PMID:10826816", "PMID:11321109", "PMID:11411711", "PMID:11931184", "PMID:13403276", "PMID:15176735", "PMID:16350067", "PMID:16403858", "PMID:25288662", "PMID:8863441", "PMID:8995799" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Asterococcus", "Asteromyces", "Borrelomyces", "Bovimyces", "Eperythrozoon", "Haemobartonella", "Pleuropneumonia" ; a owl:Class ; rdfs:label "Mycoplasma" ; rdfs:subClassOf obo:NCBITaxon_2092 . obo:NCBITaxon_2096 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:4" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mycoplasma gallisepticum" ; a owl:Class ; rdfs:label "Mycoplasmoides gallisepticum" ; rdfs:subClassOf obo:NCBITaxon_544448 . obo:NCBITaxon_2099 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:4", "PMID:11491338", "PMID:1316139", "PMID:1374621", "PMID:8573513" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mycoplasma suipneumoniae" ; a owl:Class ; rdfs:label "Mesomycoplasma hyopneumoniae" ; rdfs:subClassOf obo:NCBITaxon_2092 . obo:NCBITaxon_210 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:219" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11931154", "PMID:1995031", "PMID:8186097", "PMID:8494747" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Campylobacter pylori", "Campylobacter pylori subsp. pylori", "Campylobacter pyloridis", "Helicobacter nemestrinae" ; a owl:Class ; rdfs:label "Helicobacter pylori" ; rdfs:subClassOf obo:NCBITaxon_213849 . obo:NCBITaxon_2109 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:4" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mycoplasma synoviae" ; a owl:Class ; rdfs:label "Mycoplasmopsis synoviae" ; rdfs:subClassOf obo:NCBITaxon_2092 . obo:NCBITaxon_211880 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Leptospira canicola" ; a owl:Class ; rdfs:label "Leptospira interrogans serovar Canicola" ; rdfs:subClassOf obo:NCBITaxon_173 . obo:NCBITaxon_213849 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:11", "PMID:16403855" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Campylobacterales" ; rdfs:subClassOf obo:NCBITaxon_2 . obo:NCBITaxon_2157 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superkingdom ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10425795", "PMID:10425796", "PMID:10425797", "PMID:10490293", "PMID:10843050", "PMID:10939651", "PMID:10939673", "PMID:10939677", "PMID:11211268", "PMID:11321083", "PMID:11321113", "PMID:11411719", "PMID:11540071", "PMID:11541975", "PMID:11542064", "PMID:11542149", "PMID:11760965", "PMID:12054223", "PMID:2112744", "PMID:25527841", "PMID:270744", "PMID:32628106", "PMID:36748408", "PMID:8123559", "PMID:8590690", "PMID:9103655", "PMID:9336922" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Archaebacteria", "Mendosicutes", "Metabacteria", "Monera", "Procaryotae", "Prokaryota", "Prokaryotae", "archaea", "prokaryote", "prokaryotes" ; a owl:Class ; rdfs:label "Archaea" ; rdfs:subClassOf obo:OBI_0100026 . obo:NCBITaxon_2169991 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11619" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Argentinian mammarenavirus", "Junin arenavirus", "Junin mammarenavirus", "Junin virus", "Junn mammarenavirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mammarenavirus juninense" ; rdfs:subClassOf obo:NCBITaxon_1653394 . obo:NCBITaxon_224914 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11756688" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Brucella melitensis ATCC 23456" ; a owl:Class ; rdfs:label "Brucella melitensis bv. 1 str. 16M" ; rdfs:subClassOf obo:NCBITaxon_29459 . obo:NCBITaxon_234 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:28066370", "PMID:32373076", "PMID:35335701", "PMID:37395662", "PMID:8573514" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Brucella" ; rdfs:subClassOf obo:NCBITaxon_28211 . obo:NCBITaxon_235 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Brucella melitensis bv. Abortus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "\"Bacillus of abortion\" Bang 1897", "Bacterium abortus", "Brucella melitensis biovar Abortus" ; a owl:Class ; rdfs:label "Brucella abortus" ; rdfs:subClassOf obo:NCBITaxon_234 . obo:NCBITaxon_236 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Brucella melitensis bv. Ovis" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Brucella melitensis biovar Ovis" ; a owl:Class ; rdfs:label "Brucella ovis" ; rdfs:subClassOf obo:NCBITaxon_234 . obo:NCBITaxon_2497569 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_phylum ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Negative-strand RNA viruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Negarnaviricota" ; rdfs:subClassOf obo:NCBITaxon_2732396 . obo:NCBITaxon_2497571 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subphylum ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Polyploviricotina" ; rdfs:subClassOf obo:NCBITaxon_2497569 . obo:NCBITaxon_2501931 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthocoronavirinae" ; rdfs:subClassOf obo:NCBITaxon_11118 . obo:NCBITaxon_2559587 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "RNA viruses", "RNA viruses and viroids" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Riboviria" ; rdfs:subClassOf obo:NCBITaxon_10239 . obo:NCBITaxon_2560069 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Avulavirinae" ; rdfs:subClassOf obo:NCBITaxon_11158 . obo:NCBITaxon_2560076 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthoparamyxovirinae" ; rdfs:subClassOf obo:NCBITaxon_11158 . obo:NCBITaxon_2560080 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rubulavirinae" ; rdfs:subClassOf obo:NCBITaxon_11158 . obo:NCBITaxon_2560319 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:11176" ; oboInOwl:hasBroadSynonym "NDV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avian Paramyxovirus Serotype I", "Avian paramyxovirus type 1", "Avian paramyxovirus type-1", "Newcastle disease virus", "Newcastle disease virus NDV", "avian paramyxovirus 1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Avian avulavirus 1" ; a owl:Class ; rdfs:label "Avian orthoavulavirus 1" ; rdfs:subClassOf obo:NCBITaxon_2560069 . obo:NCBITaxon_2560602 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:11161", "NCBITaxon:1979165" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Mumps virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mumps rubulavirus" ; a owl:Class ; rdfs:label "Mumps orthorubulavirus" ; rdfs:subClassOf obo:NCBITaxon_2560080 . obo:NCBITaxon_260963 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Avulavirus" ; rdfs:subClassOf obo:NCBITaxon_2560069 . obo:NCBITaxon_260964 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Henipavirus" ; rdfs:subClassOf obo:NCBITaxon_2560076 . obo:NCBITaxon_2611341 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1", "PMID:30257078" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Metamonada" ; rdfs:subClassOf obo:NCBITaxon_2759 . obo:NCBITaxon_2611352 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Discoba" ; rdfs:subClassOf obo:NCBITaxon_2759 . obo:NCBITaxon_262698 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11", "PMID:15805518" ; oboInOwl:hasExactSynonym "Brucella abortus biovar 1 str. 9-941", "Brucella abortus bv. 1 strain 9-941" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Brucella abortus bv. 1 str. 9-941" ; rdfs:subClassOf obo:NCBITaxon_235 . obo:NCBITaxon_263 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacterium tularense", "Brucella tularensis", "Francisella tularense", "Pasteurella tularensis" ; a owl:Class ; rdfs:label "Francisella tularensis" ; rdfs:subClassOf obo:NCBITaxon_72273 . obo:NCBITaxon_2697049 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "SARS-CoV-2" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "2019-nCoV", "COVID-19 virus", "HCoV-19", "Human coronavirus 2019", "SARS-2", "SARS-CoV2", "SARS2" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Severe acute respiratory syndrome coronavirus 2" ; rdfs:subClassOf obo:NCBITaxon_694009 . obo:NCBITaxon_2732005 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_kingdom ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bamfordvirae" ; rdfs:subClassOf obo:NCBITaxon_10239 . obo:NCBITaxon_2732092 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_kingdom ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Shotokuvirae" ; rdfs:subClassOf obo:NCBITaxon_10239 . obo:NCBITaxon_2732396 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_kingdom ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthornavirae" ; rdfs:subClassOf obo:NCBITaxon_2559587 . obo:NCBITaxon_2732406 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_phylum ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Kitrinoviricota" ; rdfs:subClassOf obo:NCBITaxon_2732396 . obo:NCBITaxon_2732415 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_phylum ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Cossaviricota" ; rdfs:subClassOf obo:NCBITaxon_2732092 . obo:NCBITaxon_2732421 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Papovaviricetes" ; rdfs:subClassOf obo:NCBITaxon_2732415 . obo:NCBITaxon_2732461 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Alsuviricetes" ; rdfs:subClassOf obo:NCBITaxon_2732406 . obo:NCBITaxon_2732506 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Pisoniviricetes" ; rdfs:subClassOf obo:NCBITaxon_2732396 . obo:NCBITaxon_2732514 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Revtraviricetes" ; rdfs:subClassOf obo:NCBITaxon_2559587 . obo:NCBITaxon_2732525 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Pokkesviricetes" ; rdfs:subClassOf obo:NCBITaxon_2732005 . obo:NCBITaxon_2732541 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasAlternativeId "NCBITaxon:10880" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Reoviridae" ; a owl:Class ; rdfs:label "Reovirales" ; rdfs:subClassOf obo:NCBITaxon_2732396 . obo:NCBITaxon_2732543 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Hepelivirales" ; rdfs:subClassOf obo:NCBITaxon_2732461 . obo:NCBITaxon_2759 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superkingdom ; oboInOwl:hasDbXref "GC_ID:1", "PMID:23020233", "PMID:30257078" ; oboInOwl:hasExactSynonym "eucaryotes", "eukaryotes" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Eucarya", "Eucaryotae", "Eukarya", "Eukaryotae", "eukaryotes" ; a owl:Class ; rdfs:label "Eukaryota" ; rdfs:subClassOf obo:OBI_0100026 . obo:NCBITaxon_27592 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovinae" ; rdfs:subClassOf obo:NCBITaxon_9895 . obo:NCBITaxon_28115 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:29525" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1503973" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacteroides macacae", "Bacteroides melaninogenicus subsp. macacae", "Bacteroides salivosus", "Porphyromonas salivosa" ; a owl:Class ; rdfs:label "Porphyromonas macacae" ; rdfs:subClassOf obo:NCBITaxon_836 . obo:NCBITaxon_28174 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:707" ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Listonella ordalii" ; a owl:Class ; rdfs:label "Vibrio ordalii" ; rdfs:subClassOf obo:NCBITaxon_641 . obo:NCBITaxon_28211 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11541974", "PMID:11837318", "PMID:16166687", "PMID:16403855", "PMID:19060069" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Alphabacteria", "Proteobacteria alpha subdivision", "Purple bacteria, alpha subdivision", "a-proteobacteria", "alpha proteobacteria", "alpha subdivision", "alpha subgroup" ; a owl:Class ; rdfs:label "Alphaproteobacteria" ; rdfs:subClassOf obo:NCBITaxon_1224 . obo:NCBITaxon_28216 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:11", "PMID:16403855", "PMID:28581923" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Proteobacteria beta subdivision", "Purple bacteria, beta subdivision", "b-proteobacteria", "beta proteobacteria", "beta subdivision", "beta subgroup" ; a owl:Class ; rdfs:label "Betaproteobacteria" ; rdfs:subClassOf obo:NCBITaxon_1224 . obo:NCBITaxon_28344 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:12796", "NCBITaxon:70172" ; oboInOwl:hasBroadSynonym "PRRSV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Porcine reproductive and respiratory syndrome virus (PRRSV)", "Porcine respiratory and reproductive syndrome virus", "porcine reproductive and respiratory syndrome virus PRRSV", "porcine reproductive and respiratory syndrome virus, PRRSV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Porcine reproductive and respiratory syndrome virus" ; rdfs:subClassOf obo:NCBITaxon_76803 . obo:NCBITaxon_28450 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1435366", "NCBITaxon:1435368", "NCBITaxon:1435988", "NCBITaxon:1439853", "NCBITaxon:1487954", "NCBITaxon:1487955" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:12734250", "PMID:1283774" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus pseudomallei", "Bacterium whitmori", "Loefflerella pseudomallei", "Malleomyces pseudomallei", "Pseudomonas pseudomallei" ; a owl:Class ; rdfs:label "Burkholderia pseudomallei" ; rdfs:subClassOf obo:NCBITaxon_80840 . obo:NCBITaxon_286 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:212745" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10758879", "PMID:10939664", "PMID:15950132", "PMID:18048745", "PMID:23918787", "PMID:7727274", "PMID:9103607" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "\"Chlorobacterium\" Guillebeau 1890, nom. rejic. Opin. 6 (not \"Chlorobacterium\" Lauterborn 1916)", "Liquidomonas", "Loefflerella", "RNA similarity group I" ; a owl:Class ; rdfs:label "Pseudomonas" ; rdfs:subClassOf obo:NCBITaxon_1236 . obo:NCBITaxon_287 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1224290", "NCBITaxon:1437768", "NCBITaxon:1437769", "NCBITaxon:1437770", "NCBITaxon:1508364", "NCBITaxon:1607811", "NCBITaxon:1607813", "NCBITaxon:1683559", "NCBITaxon:1683561", "NCBITaxon:1851858", "NCBITaxon:1851865", "NCBITaxon:1860124", "NCBITaxon:665948", "NCBITaxon:912077", "NCBITaxon:931955", "NCBITaxon:931956", "NCBITaxon:931957", "NCBITaxon:931958", "NCBITaxon:932477" ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus aeruginosus", "Bacillus pyocyaneus", "Bacterium aeruginosum", "Bacterium pyocyaneum", "Micrococcus pyocyaneus", "Pseudomonas polycolor", "Pseudomonas pyocyanea", "probable synonym or variety: \"Pseudomonas polycolor\" Clara 1930" ; a owl:Class ; rdfs:label "Pseudomonas aeruginosa" ; rdfs:subClassOf obo:NCBITaxon_286 . obo:NCBITaxon_29176 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Neospora caninum" ; rdfs:subClassOf obo:NCBITaxon_5809 . obo:NCBITaxon_29459 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:8573514" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Micrococcus melitensis", "Streptococcus Miletensis" ; a owl:Class ; rdfs:label "Brucella melitensis" ; rdfs:subClassOf obo:NCBITaxon_234 . obo:NCBITaxon_29461 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Brucella melitensis bv. Suis" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Brucella melitensis biovar Suis" ; a owl:Class ; rdfs:label "Brucella suis" ; rdfs:subClassOf obo:NCBITaxon_234 . obo:NCBITaxon_2946186 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasAlternativeId "NCBITaxon:689832" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Sedoreovirinae" ; a owl:Class ; rdfs:label "Sedoreoviridae" ; rdfs:subClassOf obo:NCBITaxon_2732541 . obo:NCBITaxon_2946633 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Heptrevirinae" ; rdfs:subClassOf obo:NCBITaxon_12058 . obo:NCBITaxon_29486 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Yersinia ruckeri" ; rdfs:subClassOf obo:NCBITaxon_629 . obo:NCBITaxon_29546 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:7547305", "PMID:7857801", "PMID:7981108", "PMID:8123559", "PMID:8347512", "PMID:9226893" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Candidatus intracellularis", "Ileal symbiont intracellularis" ; a owl:Class ; rdfs:label "Lawsonia intracellularis" ; rdfs:subClassOf obo:NCBITaxon_2 . obo:NCBITaxon_3044472 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthoherpesviridae" ; rdfs:subClassOf obo:NCBITaxon_548681 . obo:NCBITaxon_3044782 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthoflavivirus" ; rdfs:subClassOf obo:NCBITaxon_11050 . obo:NCBITaxon_3052223 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:45337", "NCBITaxon:63330" ; oboInOwl:hasDbXref "GC_ID:1", "PMID:7701348" ; oboInOwl:hasExactSynonym "Equine morbillivirus", "Hendra henipavirus", "Hendra virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Henipavirus hendraense" ; rdfs:subClassOf obo:NCBITaxon_260964 . obo:NCBITaxon_3052225 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:121791" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Nipah henipavirus", "Nipah virus", "Nipah-virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Henipavirus nipahense" ; rdfs:subClassOf obo:NCBITaxon_260964 . obo:NCBITaxon_3052230 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11103" ; oboInOwl:hasBroadSynonym "HCV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Hepacivirus C", "Hepatitis C virus", "hepatitis C virus HCV", "human hepatitis C virus", "human hepatitis C virus HCV", "human hepatitis virus C HCV", "post-transfusion hepatitis non A non B virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Hepacivirus hominis" ; rdfs:subClassOf obo:NCBITaxon_11050 . obo:NCBITaxon_3052303 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11623", "NCBITaxon:12748" ; oboInOwl:hasBroadSynonym "LCMV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Lymphocytic choriomeningitis mammarenavirus", "Lymphocytic choriomeningitis virus", "lymphocytic choriomeningitis virus LCMV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mammarenavirus choriomeningitidis" ; rdfs:subClassOf obo:NCBITaxon_1653394 . obo:NCBITaxon_3052310 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11620" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Lassa mammarenavirus", "Lassa virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Mammarenavirus lassaense" ; rdfs:subClassOf obo:NCBITaxon_1653394 . obo:NCBITaxon_3052342 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11232" ; oboInOwl:hasBroadSynonym "CDV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Canine distemper virus", "Canine morbillivirus", "canine distemper virus CDV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Morbillivirus canis" ; rdfs:subClassOf obo:NCBITaxon_11229 . obo:NCBITaxon_3052518 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11593", "NCBITaxon:1980519" ; oboInOwl:hasBroadSynonym "CCHFV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Crimean-Congo haemorrhagic fever virus", "Crimean-Congo hemorrhagic fever nairovirus", "Crimean-Congo hemorrhagic fever orthonairovirus", "Crimean-Congo hemorrhagic virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Crimean-Congo hemorrhagic fever virus" ; a owl:Class ; rdfs:label "Orthonairovirus haemorrhagiae" ; rdfs:subClassOf obo:NCBITaxon_1980410 . obo:NCBITaxon_3052707 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1511906" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Carnivore protoparvovirus 1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Protoparvovirus carnivoran1" ; rdfs:subClassOf obo:NCBITaxon_1506574 . obo:NCBITaxon_3052729 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:11215" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Bovine parainfluenza 3 virus", "Bovine parainfluenza virus 3", "Bovine parainfluenza virus type 3", "Bovine respirovirus 3" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Respirovirus bovis" ; rdfs:subClassOf obo:NCBITaxon_2560076 . obo:NCBITaxon_3072906 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Musteloidea" ; rdfs:subClassOf obo:NCBITaxon_379584 . obo:NCBITaxon_314145 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superorder ; oboInOwl:hasDbXref "GC_ID:1", "PMID:11214318", "PMID:11214319", "PMID:12878460" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Laurasiatheria" ; rdfs:subClassOf obo:NCBITaxon_1437010 . obo:NCBITaxon_314146 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superorder ; oboInOwl:hasDbXref "GC_ID:1", "PMID:11214319", "PMID:12082125", "PMID:12878460", "PMID:15522813" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Euarchontoglires" ; rdfs:subClassOf obo:NCBITaxon_1437010 . obo:NCBITaxon_314147 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1", "PMID:11214319", "PMID:12082125", "PMID:15522813" ; oboInOwl:hasExactSynonym "Rodents and rabbits" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Glires" ; rdfs:subClassOf obo:NCBITaxon_314146 . obo:NCBITaxon_314293 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_infraorder ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Anthropoidea" ; a owl:Class ; rdfs:label "Simiiformes" ; rdfs:subClassOf obo:NCBITaxon_9443 . obo:NCBITaxon_32524 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "amniotes" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Amniota" ; rdfs:subClassOf obo:NCBITaxon_117571 . obo:NCBITaxon_32561 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "diapsids" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Diapsida" ; a owl:Class ; rdfs:label "Sauria" ; rdfs:subClassOf obo:NCBITaxon_32524 . obo:NCBITaxon_327045 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Orthoretrovirinae" ; rdfs:subClassOf obo:NCBITaxon_2732514 . obo:NCBITaxon_329639 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:186155" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Canine parvovirus-1", "Minute virus of canines" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canine minute virus" ; rdfs:subClassOf obo:NCBITaxon_40119 . obo:NCBITaxon_33154 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Fungi/Metazoa group", "opisthokonts" ; a owl:Class ; rdfs:label "Opisthokonta" ; rdfs:subClassOf obo:NCBITaxon_2759 . obo:NCBITaxon_33213 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bilateria" ; rdfs:subClassOf obo:NCBITaxon_33154 . obo:NCBITaxon_33317 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Protostomia" ; rdfs:subClassOf obo:NCBITaxon_33213 . obo:NCBITaxon_33340 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_infraclass ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Neoptera" ; rdfs:subClassOf obo:NCBITaxon_1206794 . obo:NCBITaxon_333774 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "unclassified Papillomaviridae" ; rdfs:subClassOf obo:NCBITaxon_151340 . obo:NCBITaxon_33550 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_suborder ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "guinea pigs and others" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Hystricognathi" ; a owl:Class ; rdfs:label "Hystricomorpha" ; rdfs:subClassOf obo:NCBITaxon_9989 . obo:NCBITaxon_33554 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "carnivores" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "carnivores" ; a owl:Class ; rdfs:label "Carnivora" ; rdfs:subClassOf obo:NCBITaxon_314145 . obo:NCBITaxon_34085 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:13200095", "PMID:22427448", "PMID:8240957", "PMID:9103649" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Moraxella anatipestifer", "Pasteurella anapestifer", "Pasteurella anatipestifer", "Pfeifferella anatipestifer" ; a owl:Class ; rdfs:label "Riemerella anatipestifer" ; rdfs:subClassOf obo:NCBITaxon_200644 . obo:NCBITaxon_353210 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Replication competent viruses" ; rdfs:subClassOf obo:NCBITaxon_153135 . obo:NCBITaxon_35324 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "unclassified Orthomyxoviridae" ; rdfs:subClassOf obo:NCBITaxon_11308 . obo:NCBITaxon_35500 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_infraorder ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Pecora" ; rdfs:subClassOf obo:NCBITaxon_91561 . obo:NCBITaxon_359391 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11", "PMID:16299333", "PMID:20462421" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Brucella melitensis biovar Abortus 2308" ; a owl:Class ; rdfs:label "Brucella abortus 2308" ; rdfs:subClassOf obo:NCBITaxon_235 . obo:NCBITaxon_36362 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:10624" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Polyomavirus", "Polyomaviruses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Polyomavirus sp." ; rdfs:subClassOf obo:NCBITaxon_151341 . obo:NCBITaxon_36420 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "H1N1 swine influenza virus" ; rdfs:subClassOf obo:NCBITaxon_114727 . obo:NCBITaxon_36470 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Streptococcus sp. (group A)", "group A streptococci", "group A streptococcus" ; a owl:Class ; rdfs:label "Streptococcus sp. 'group A'" ; rdfs:subClassOf obo:NCBITaxon_1301 . obo:NCBITaxon_36855 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Brucella melitensis bv. Canis" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Brucella melitensis biovar Canis" ; a owl:Class ; rdfs:label "Brucella canis" ; rdfs:subClassOf obo:NCBITaxon_234 . obo:NCBITaxon_37124 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Chikungunya virus" ; rdfs:subClassOf obo:NCBITaxon_11019 . obo:NCBITaxon_379584 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_suborder ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Caniformia" ; rdfs:subClassOf obo:NCBITaxon_33554 . obo:NCBITaxon_38170 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avian reovirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Avian orthoreovirus" ; rdfs:subClassOf obo:NCBITaxon_2732541 . obo:NCBITaxon_38345 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1581182" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Leptospira grippotyphosa" ; a owl:Class ; rdfs:label "Leptospira kirschneri serovar Grippotyphosa" ; rdfs:subClassOf obo:NCBITaxon_171 . obo:NCBITaxon_38525 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avian pneumovirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Avian metapneumovirus" ; rdfs:subClassOf obo:NCBITaxon_162387 . obo:NCBITaxon_38568 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subgenus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Leishmania" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Leishmania " ; rdfs:subClassOf obo:NCBITaxon_5658 . obo:NCBITaxon_38574 obo:IAO_0000412 ; ncbitaxon:has_rank ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Leishmania donovani species complex" ; rdfs:subClassOf obo:NCBITaxon_38568 . obo:NCBITaxon_39107 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasAlternativeId "NCBITaxon:109679" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Murinae" ; rdfs:subClassOf obo:NCBITaxon_9989 . obo:NCBITaxon_391902 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subspecies ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bos bubalis bubalis" ; a owl:Class ; rdfs:label "Bubalus bubalis bubalis" ; rdfs:subClassOf obo:NCBITaxon_27592 . obo:NCBITaxon_393305 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Yersinia enterocolitica subsp. enterocolitica str. 8081", "Yersinia enterocolitica subsp. enterocolitica strain 8081" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Yersinia enterocolitica subsp. enterocolitica 8081" ; rdfs:subClassOf obo:NCBITaxon_150052 . obo:NCBITaxon_39744 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rubulavirus" ; rdfs:subClassOf obo:NCBITaxon_2560080 . obo:NCBITaxon_39944 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "CpHV-1" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Caprine herpesvirus 1", "Caprine herpesvirus type 1", "goat herpesvirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Caprine alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_10319 . obo:NCBITaxon_40050 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:10896" ; oboInOwl:hasBroadSynonym "AHSV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "African horse sickness group", "African horse sickness virus (AHSV)", "African horsesickness virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "African horse sickness virus AHSV" ; a owl:Class ; rdfs:label "African horse sickness virus" ; rdfs:subClassOf obo:NCBITaxon_10892 . obo:NCBITaxon_40051 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:12591" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Bluetongue virus group", "bluetongue virus BTV" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bluetongue virus" ; rdfs:subClassOf obo:NCBITaxon_10892 . obo:NCBITaxon_400570 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Quailpox virus" ; rdfs:subClassOf obo:NCBITaxon_10260 . obo:NCBITaxon_40119 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Parvovirinae" ; rdfs:subClassOf obo:NCBITaxon_2732415 . obo:NCBITaxon_40269 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:18048732" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Vibrio salmonicida" ; a owl:Class ; rdfs:label "Aliivibrio salmonicida" ; rdfs:subClassOf obo:NCBITaxon_641 . obo:NCBITaxon_40674 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "mammals" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "mammals" ; a owl:Class ; rdfs:label "Mammalia" ; rdfs:subClassOf obo:NCBITaxon_32524 . obo:NCBITaxon_41678 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasBroadSynonym "TAdV-3" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Marble spleen disease virus", "Turkey adenovirus serotype 3", "Turkey haemorrhagic enteritis virus", "Turkey hemorrhagic enteritis virus", "hemorrhagic enteritis virus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Turkey adenovirus 3" ; rdfs:subClassOf obo:NCBITaxon_10508 . obo:NCBITaxon_418101 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subgenus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Vinckeia" ; a owl:Class ; rdfs:label "Plasmodium (Vinckeia)" ; rdfs:subClassOf obo:NCBITaxon_5820 . obo:NCBITaxon_418103 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subgenus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Plasmodium" ; a owl:Class ; rdfs:label "Plasmodium (Plasmodium)" ; rdfs:subClassOf obo:NCBITaxon_5820 . obo:NCBITaxon_422676 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Hematozoa Vivier 1982" ; a owl:Class ; rdfs:label "Aconoidasida" ; rdfs:subClassOf obo:NCBITaxon_5794 . obo:NCBITaxon_423054 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_suborder ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Eimeriorina" ; rdfs:subClassOf obo:NCBITaxon_5794 . obo:NCBITaxon_42890 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Sarcocystis neurona" ; rdfs:subClassOf obo:NCBITaxon_5809 . obo:NCBITaxon_430066 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Brucella abortus str. S19", "Brucella abortus strain S19" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Brucella abortus S19" ; rdfs:subClassOf obo:NCBITaxon_235 . obo:NCBITaxon_44088 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasBroadSynonym "CNPV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Avipoxvirus clade B1", "Canary poxvirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canarypox virus" ; rdfs:subClassOf obo:NCBITaxon_10260 . obo:NCBITaxon_444163 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:399128" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:18218934" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Brucella microti" ; rdfs:subClassOf obo:NCBITaxon_234 . obo:NCBITaxon_444178 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Brucella ovis str. ATCC 25840", "Brucella ovis strain ATCC 25840" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Brucella ovis ATCC 25840" ; rdfs:subClassOf obo:NCBITaxon_236 . obo:NCBITaxon_464095 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Picornavirales" ; rdfs:subClassOf obo:NCBITaxon_2732506 . obo:NCBITaxon_470137 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11", "PMID:19346311" ; oboInOwl:hasExactSynonym "Brucella suis str. ATCC 23445", "Brucella suis strain ATCC 23445" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Brucella suis ATCC 23445" ; rdfs:subClassOf obo:NCBITaxon_29461 . obo:NCBITaxon_4751 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_kingdom ; oboInOwl:hasDbXref "GC_ID:1", "PMID:11062127", "PMID:12684019" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mycota", "fungi" ; a owl:Class ; rdfs:label "Fungi" ; rdfs:subClassOf obo:NCBITaxon_33154 . obo:NCBITaxon_483179 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11", "PMID:19346311" ; oboInOwl:hasExactSynonym "Brucella canis str. ATCC 23365", "Brucella canis strain ATCC 23365" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Brucella canis ATCC 23365" ; rdfs:subClassOf obo:NCBITaxon_36855 . obo:NCBITaxon_487 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Diplokokkus intracellularis meningitidis", "Micrococcus intracellularis", "Micrococcus meningitidis", "Micrococcus meningitidis cerebrospinalis", "Neisseria weichselbaumii" ; a owl:Class ; rdfs:label "Neisseria meningitidis" ; rdfs:subClassOf obo:NCBITaxon_206351 . obo:NCBITaxon_50294 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "PsHV-1" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Pacheco's disease virus", "Psittacid herpesvirus 1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Psittacid alphaherpesvirus 1" ; rdfs:subClassOf obo:NCBITaxon_180255 . obo:NCBITaxon_504568 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "trouts, salmons & chars" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Salmoninae" ; rdfs:subClassOf obo:NCBITaxon_8015 . obo:NCBITaxon_517 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11491321" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bordetella" ; rdfs:subClassOf obo:NCBITaxon_80840 . obo:NCBITaxon_518 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:514" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:8240949", "PMID:8782670", "PMID:9226899" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Alcaligenes bronchicanis", "Alcaligenes bronchisepticus", "Bacillus bronchicanis", "Bacillus bronchisepticus", "Bacterium bronchisepticus", "Brucella bronchiseptica", "Haemophilus bronchisepticus" ; a owl:Class ; rdfs:label "Bordetella bronchiseptica" ; rdfs:subClassOf obo:NCBITaxon_517 . obo:NCBITaxon_520 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:8240949" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacterium tussis-convulsivae", "Haemophilus pertussis", "Hemophilus pertussis", "Microbe de la coqueluche" ; a owl:Class ; rdfs:label "Bordetella pertussis" ; rdfs:subClassOf obo:NCBITaxon_517 . obo:NCBITaxon_521 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:4074238" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bordetella avium" ; rdfs:subClassOf obo:NCBITaxon_517 . obo:NCBITaxon_543 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10555323", "PMID:10555334", "PMID:16166704", "PMID:27620848" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Enterobacteraceae", "enterobacteria", "gamma-3 proteobacteria" ; a owl:Class ; rdfs:label "Enterobacteriaceae" ; rdfs:subClassOf obo:NCBITaxon_91347 . obo:NCBITaxon_54315 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:136447", "NCBITaxon:64986", "NCBITaxon:96055" ; oboInOwl:hasBroadSynonym "BVDV type II", "BVDV-2" ; oboInOwl:hasDbXref "GC_ID:1", "PMID:7747470" ; oboInOwl:hasExactSynonym "Bovine viral diarrhea virus genotype 2", "Bovine viral diarrhea virus type 2", "Bovine viral diarrhea virus-2", "bovine viral diarrhea virus type II", "pestivirus type 4" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovine viral diarrhea virus 2" ; rdfs:subClassOf obo:NCBITaxon_11095 . obo:NCBITaxon_544448 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_phylum ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Tenericutes" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "\"Mollicutaeota\" Oren et al. 2015", "\"Tenericutes\" Murray 1984", "Mollicutota" ; a owl:Class ; rdfs:label "Mycoplasmatota" ; rdfs:subClassOf obo:NCBITaxon_1783272 . obo:NCBITaxon_546272 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasDbXref "GC_ID:11", "PMID:19346311" ; oboInOwl:hasExactSynonym "Brucella melitensis str. ATCC 23457", "Brucella melitensis strain ATCC 23457" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Brucella melitensis ATCC 23457" ; rdfs:subClassOf obo:NCBITaxon_29459 . obo:NCBITaxon_548681 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Herpesvirales" ; rdfs:subClassOf obo:NCBITaxon_10239 . obo:NCBITaxon_5500 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Coccidioides" ; rdfs:subClassOf obo:NCBITaxon_4751 . obo:NCBITaxon_55601 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:28167", "NCBITaxon:665" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:21296930" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Achromobacter ichthyodermis", "Listonella anguillara", "Listonella anguillarum", "Pseudomonas ichthyodermis", "Vibrio ichthyodermis", "Vibrio piscium", "Vibrio piscium var. japonicus" ; a owl:Class ; rdfs:label "Vibrio anguillarum" ; rdfs:subClassOf obo:NCBITaxon_662 . obo:NCBITaxon_55987 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:155284", "NCBITaxon:86501" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Salmon isavirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Isavirus salaris" ; rdfs:subClassOf obo:NCBITaxon_11308 . obo:NCBITaxon_560210 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Dintheria" ; rdfs:subClassOf obo:NCBITaxon_119088 . obo:NCBITaxon_562 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1637691", "NCBITaxon:1806490", "NCBITaxon:469598", "NCBITaxon:662101", "NCBITaxon:662104" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319482" ; oboInOwl:hasExactSynonym "E. coli", "Escherichia/Shigella coli" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus coli", "Bacterium coli", "Bacterium coli commune", "Enterococcus coli" ; a owl:Class ; rdfs:label "Escherichia coli" ; rdfs:subClassOf obo:NCBITaxon_543 . obo:NCBITaxon_5654 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Trypanosomatidae" ; rdfs:subClassOf obo:NCBITaxon_2611352 . obo:NCBITaxon_5658 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Leishmania" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Leishmania " ; rdfs:subClassOf obo:NCBITaxon_5654 . obo:NCBITaxon_5659 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:31284" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Leishmania (Leishmania) amazonensis", "Leishmania mexicana amazonensis" ; a owl:Class ; rdfs:label "Leishmania amazonensis" ; rdfs:subClassOf obo:NCBITaxon_38568 . obo:NCBITaxon_5661 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Leishmania (Leishmania) donovani" ; a owl:Class ; rdfs:label "Leishmania donovani" ; rdfs:subClassOf obo:NCBITaxon_38574 . obo:NCBITaxon_5664 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Leishmania (Leishmania) major", "Leishmania tropica major" ; a owl:Class ; rdfs:label "Leishmania major" ; rdfs:subClassOf obo:NCBITaxon_38568 . obo:NCBITaxon_56690 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:33701", "NCBITaxon:5724" ; oboInOwl:hasDbXref "GC_ID:1", "PMID:12046599", "PMID:15734659", "PMID:22000167" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Tritrichomonas suis" ; rdfs:subClassOf obo:NCBITaxon_2611341 . obo:NCBITaxon_5671 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:5662" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Leishmania (Leishmania) infantum", "Leishmania donovani infantum" ; a owl:Class ; rdfs:label "Leishmania infantum" ; rdfs:subClassOf obo:NCBITaxon_38574 . obo:NCBITaxon_568815 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_strain ; oboInOwl:hasAlternativeId "NCBITaxon:399127" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:19653890" ; oboInOwl:hasExactSynonym "Brucella microti str. CCM 4915", "Brucella microti strain CCM 4915" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Brucella sp. CCM 4915" ; a owl:Class ; rdfs:label "Brucella microti CCM 4915" ; rdfs:subClassOf obo:NCBITaxon_444163 . obo:NCBITaxon_5690 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Trypanosoma" ; rdfs:subClassOf obo:NCBITaxon_5654 . obo:NCBITaxon_5691 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Trypanosoma (Trypanozoon) brucei", "Trypanosoma brucei subgroup" ; a owl:Class ; rdfs:label "Trypanosoma brucei" ; rdfs:subClassOf obo:NCBITaxon_5690 . obo:NCBITaxon_5693 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Trypanosoma cruzi" ; rdfs:subClassOf obo:NCBITaxon_5690 . obo:NCBITaxon_5741 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1", "PMID:11432808", "PMID:19135417" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Giardia duodenalis", "Giardia lamblia", "Lamblia intestinalis" ; a owl:Class ; rdfs:label "Giardia intestinalis" ; rdfs:subClassOf obo:NCBITaxon_2611341 . obo:NCBITaxon_5759 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Entamoeba histolytica" ; rdfs:subClassOf obo:NCBITaxon_2759 . obo:NCBITaxon_5761 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Naegleria" ; rdfs:subClassOf obo:NCBITaxon_2611352 . obo:NCBITaxon_5762 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Naegleria gruberi" ; rdfs:subClassOf obo:NCBITaxon_5761 . obo:NCBITaxon_5763 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "brain-eating amoeba" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Naegleria fowleri" ; rdfs:subClassOf obo:NCBITaxon_5761 . obo:NCBITaxon_5794 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_phylum ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "apicomplexans" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "apicomplexans" ; a owl:Class ; rdfs:label "Apicomplexa" ; rdfs:subClassOf obo:NCBITaxon_2759 . obo:NCBITaxon_5800 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Eimeria" ; rdfs:subClassOf obo:NCBITaxon_423054 . obo:NCBITaxon_5802 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Eimeria tenella" ; rdfs:subClassOf obo:NCBITaxon_5800 . obo:NCBITaxon_5804 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Eimeria maxima" ; rdfs:subClassOf obo:NCBITaxon_5800 . obo:NCBITaxon_5807 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:2200815", "NCBITaxon:2200816", "NCBITaxon:2200817", "NCBITaxon:2200818", "NCBITaxon:2200819", "NCBITaxon:2200820", "NCBITaxon:2200821", "NCBITaxon:2200822", "NCBITaxon:2200823", "NCBITaxon:2200824", "NCBITaxon:2200825", "NCBITaxon:2200826" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Cryptosporidium parvum" ; rdfs:subClassOf obo:NCBITaxon_423054 . obo:NCBITaxon_5809 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Sarcocystids" ; a owl:Class ; rdfs:label "Sarcocystidae" ; rdfs:subClassOf obo:NCBITaxon_423054 . obo:NCBITaxon_5811 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Toxoplasma gondii" ; rdfs:subClassOf obo:NCBITaxon_5809 . obo:NCBITaxon_5820 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Plasmodium" ; rdfs:subClassOf obo:NCBITaxon_422676 . obo:NCBITaxon_5821 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Plasmodium berghei" ; rdfs:subClassOf obo:NCBITaxon_418101 . obo:NCBITaxon_5825 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Plasmodium chabaudi" ; rdfs:subClassOf obo:NCBITaxon_418101 . obo:NCBITaxon_5833 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "malaria parasite P. falciparum" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Plasmodium (Laverania) falciparum" ; a owl:Class ; rdfs:label "Plasmodium falciparum" ; rdfs:subClassOf obo:NCBITaxon_5820 . obo:NCBITaxon_5850 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Plasmodium knowlesi" ; rdfs:subClassOf obo:NCBITaxon_418103 . obo:NCBITaxon_5855 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "malaria parasite P. vivax" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Haemamoeba vivax", "Haemamoeba vivax Grassi and Feletti, 1890" ; a owl:Class ; rdfs:label "Plasmodium vivax" ; rdfs:subClassOf obo:NCBITaxon_418103 . obo:NCBITaxon_5861 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Plasmodium yoelli" ; a owl:Class ; rdfs:label "Plasmodium yoelii" ; rdfs:subClassOf obo:NCBITaxon_418101 . obo:NCBITaxon_5863 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Piroplasmids" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Piroplasmida" ; rdfs:subClassOf obo:NCBITaxon_422676 . obo:NCBITaxon_5864 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Babesia" ; rdfs:subClassOf obo:NCBITaxon_5863 . obo:NCBITaxon_5865 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Babesia bovis" ; rdfs:subClassOf obo:NCBITaxon_5864 . obo:NCBITaxon_5866 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Babesia bigemina" ; rdfs:subClassOf obo:NCBITaxon_5864 . obo:NCBITaxon_5867 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Babesia canis" ; rdfs:subClassOf obo:NCBITaxon_5864 . obo:NCBITaxon_5873 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Theileria" ; rdfs:subClassOf obo:NCBITaxon_5863 . obo:NCBITaxon_5874 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Theileria annulata" ; rdfs:subClassOf obo:NCBITaxon_5873 . obo:NCBITaxon_5875 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Theileria parva" ; rdfs:subClassOf obo:NCBITaxon_5873 . obo:NCBITaxon_590 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319519", "PMID:10939679", "PMID:12072558", "PMID:15653929", "PMID:15653930", "PMID:3231714", "PMID:37486130", "PMID:9731304" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Salmonella" ; rdfs:subClassOf obo:NCBITaxon_543 . obo:NCBITaxon_59201 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subspecies ; oboInOwl:hasAlternativeId "NCBITaxon:149049" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:15653929", "PMID:15653930", "PMID:7149525" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Salmonella cholerae-suis subsp. cholerae-suis", "Salmonella choleraesuis subsp. choleraesuis", "Salmonella enterica I", "Salmonella enterica subsp. I", "Salmonella enterica subsp. Subsp. I", "Salmonella enterica subsp. Subsp. Ixxx" ; a owl:Class ; rdfs:label "Salmonella enterica subsp. enterica" ; rdfs:subClassOf obo:NCBITaxon_590 . obo:NCBITaxon_594 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:41510" ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Salmonella enterica serovar Gallinarum", "Salmonella gallinarum" ; a owl:Class ; rdfs:label "Salmonella enterica subsp. enterica serovar Gallinarum" ; rdfs:subClassOf obo:NCBITaxon_59201 . obo:NCBITaxon_6181 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Schistosoma" ; rdfs:subClassOf obo:NCBITaxon_33317 . obo:NCBITaxon_6182 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Schistosoma japonicum" ; rdfs:subClassOf obo:NCBITaxon_6181 . obo:NCBITaxon_6183 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Schistosoma mansoni" ; rdfs:subClassOf obo:NCBITaxon_6181 . obo:NCBITaxon_619591 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Monkeypox virus Zaire-96-I-16" ; rdfs:subClassOf obo:NCBITaxon_10244 . obo:NCBITaxon_620 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:26834722" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Shigella" ; rdfs:subClassOf obo:NCBITaxon_543 . obo:NCBITaxon_622 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:12054222" ; oboInOwl:hasExactSynonym "Escherichia/Shigella dysenteriae" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus dysenteriae", "Bacillus dysentericus", "Bacillus shigae", "Eberthella dysenteriae", "Shigella shigae" ; a owl:Class ; rdfs:label "Shigella dysenteriae" ; rdfs:subClassOf obo:NCBITaxon_620 . obo:NCBITaxon_623 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Escherichia flexneri", "Escherichia/Shigella flexneri" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Shigella paradysenteriae" ; a owl:Class ; rdfs:label "Shigella flexneri" ; rdfs:subClassOf obo:NCBITaxon_620 . obo:NCBITaxon_624 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacterium sonnei" ; a owl:Class ; rdfs:label "Shigella sonnei" ; rdfs:subClassOf obo:NCBITaxon_620 . obo:NCBITaxon_629 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Yersinia" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Yersinia " ; rdfs:subClassOf obo:NCBITaxon_1903411 . obo:NCBITaxon_632 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:15084509" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus pestis", "Bacterium pestis", "Pasteurella pestis", "Pestisella pestis", "Yersinia pseudotuberculosis subsp. pestis" ; a owl:Class ; rdfs:label "Yersinia pestis" ; rdfs:subClassOf obo:NCBITaxon_1649845 . obo:NCBITaxon_633 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1161941" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:2223608", "PMID:23919959" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus pseudotuberkulosis", "Bacterium pseudotuberculosis", "Pasteurella lymphangitidis", "Pasteurella pseudotuberculosis", "Shigella pseudotuberculosis" ; a owl:Class ; rdfs:label "Yersinia pseudotuberculosis" ; rdfs:subClassOf obo:NCBITaxon_1649845 . obo:NCBITaxon_6334 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Trichinella spiralis" ; rdfs:subClassOf obo:NCBITaxon_119088 . obo:NCBITaxon_635 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasExactSynonym "Edwardsiella" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Asakusa group", "Bartholomew group" ; a owl:Class ; rdfs:label "Edwardsiella " ; rdfs:subClassOf obo:NCBITaxon_91347 . obo:NCBITaxon_636 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1471792", "NCBITaxon:1471793" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:27539016" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Edwardsiella anguillimortifera", "Paracolobactrum anguillimortiferum" ; a owl:Class ; rdfs:label "Edwardsiella tarda" ; rdfs:subClassOf obo:NCBITaxon_635 . obo:NCBITaxon_641 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:11", "PMID:15143042", "PMID:4954820", "PMID:8427811" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "gamma-3 proteobacteria" ; a owl:Class ; rdfs:label "Vibrionaceae" ; rdfs:subClassOf obo:NCBITaxon_1236 . obo:NCBITaxon_642 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11155981", "PMID:12067377", "PMID:12807216", "PMID:1380286", "PMID:1380289", "PMID:15388703", "PMID:16560691", "PMID:17012583", "PMID:17158971", "PMID:19567585", "PMID:7520733", "PMID:8347521", "PMID:8934910" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Aeromonas" ; rdfs:subClassOf obo:NCBITaxon_1236 . obo:NCBITaxon_644 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1471787", "NCBITaxon:1471788", "NCBITaxon:329135", "NCBITaxon:329140", "NCBITaxon:346633", "NCBITaxon:346634", "NCBITaxon:582196", "NCBITaxon:582198", "NCBITaxon:582214", "NCBITaxon:582215", "NCBITaxon:582216", "NCBITaxon:582217", "NCBITaxon:582218", "NCBITaxon:582219", "NCBITaxon:582220", "NCBITaxon:582221", "NCBITaxon:582222", "NCBITaxon:582223", "NCBITaxon:582224", "NCBITaxon:582225", "NCBITaxon:582226", "NCBITaxon:582228", "NCBITaxon:582229", "NCBITaxon:582231", "NCBITaxon:582236", "NCBITaxon:582237", "NCBITaxon:582240", "NCBITaxon:582250", "NCBITaxon:582251", "NCBITaxon:582253", "NCBITaxon:582254", "NCBITaxon:582265", "NCBITaxon:582266", "NCBITaxon:582267", "NCBITaxon:582279", "NCBITaxon:582282", "NCBITaxon:582284", "NCBITaxon:582286", "NCBITaxon:582287", "NCBITaxon:582289", "NCBITaxon:582290", "NCBITaxon:582291", "NCBITaxon:582292", "NCBITaxon:582295", "NCBITaxon:582297", "NCBITaxon:582299", "NCBITaxon:582300", "NCBITaxon:582302", "NCBITaxon:582303", "NCBITaxon:582304", "NCBITaxon:582305", "NCBITaxon:582306", "NCBITaxon:582307", "NCBITaxon:582308", "NCBITaxon:582309", "NCBITaxon:582310", "NCBITaxon:582311", "NCBITaxon:582312", "NCBITaxon:582313", "NCBITaxon:582314", "NCBITaxon:582315", "NCBITaxon:582316", "NCBITaxon:582317", "NCBITaxon:582318", "NCBITaxon:582319", "NCBITaxon:582320", "NCBITaxon:582321", "NCBITaxon:582322", "NCBITaxon:582323", "NCBITaxon:582324", "NCBITaxon:98358" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:16560691", "PMID:19965992", "PMID:23485124", "PMID:932684" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Aeromonas dourgesi", "Aeromonas hydrophila (Chester 1901) Stanier 1943 (Approved Lists 1980)", "Aeromonas liquefaciens", "Bacillus hydrophilus fuscus", "Bacterium hydrophilum", "Proteus hydrophilus", "Proteus ichthyosmius", "Pseudomonas hydrophila" ; a owl:Class ; rdfs:label "Aeromonas hydrophila" ; rdfs:subClassOf obo:NCBITaxon_642 . obo:NCBITaxon_645 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1055664", "NCBITaxon:697046" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:19965992" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus salmonicida", "Bacterium salmonicida", "Proteus salmonicida" ; a owl:Class ; rdfs:label "Aeromonas salmonicida" ; rdfs:subClassOf obo:NCBITaxon_642 . obo:NCBITaxon_64895 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:1618316" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10515907", "PMID:10758897", "PMID:16585709", "PMID:24744012", "PMID:27930271", "PMID:28141502", "PMID:30154058", "PMID:30586413", "PMID:31454394", "PMID:31722850", "PMID:31836459", "PMID:32320380", "PMID:35816828", "PMID:36748499", "PMID:7981102", "PMID:8573491", "PMID:8934900", "PMID:8995795", "PMID:9336916" ; oboInOwl:hasExactSynonym "Lyme Disease Borrelia" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Borrelia burgdorferi group", "Borrelia burgdorferi sensu lato" ; a owl:Class ; rdfs:label "Borreliella" ; rdfs:subClassOf obo:NCBITaxon_136 . obo:NCBITaxon_662 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:705" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1371064", "PMID:17978204", "PMID:21057054", "PMID:21296930", "PMID:24409173", "PMID:4935323", "PMID:7520733", "PMID:8590667" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Beneckea", "Listonella", "Microspira", "Pacinia" ; a owl:Class ; rdfs:label "Vibrio" ; rdfs:subClassOf obo:NCBITaxon_641 . obo:NCBITaxon_666 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:140100", "NCBITaxon:376726" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1015934", "PMID:9272984" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillo virgola del Koch", "Bacillus cholerae", "Bacillus cholerae-asiaticae", "Kommabacillus", "Liquidivibrio cholerae", "Microspira comma", "Pacinia cholerae-asiaticae", "Spirillum cholerae", "Spirillum cholerae-asiaticae", "Vibrio albensis", "Vibrio cholera", "Vibrio cholerae biovar albensis", "Vibrio cholerae bv. albensis", "Vibrio cholerae-asiaticae", "Vibrio comma" ; a owl:Class ; rdfs:label "Vibrio cholerae" ; rdfs:subClassOf obo:NCBITaxon_662 . obo:NCBITaxon_67780 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Edwardsiella ictaluri" ; rdfs:subClassOf obo:NCBITaxon_635 . obo:NCBITaxon_691956 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:352473" ; oboInOwl:hasBroadSynonym "DHV-1" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Duck hepatitis A virus", "Duck hepatitis virus 1", "Duck hepatitis virus type 1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Avihepatovirus A" ; rdfs:subClassOf obo:NCBITaxon_12058 . obo:NCBITaxon_693995 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Coronavirinae" ; rdfs:subClassOf obo:NCBITaxon_11118 . obo:NCBITaxon_693997 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Alphacoronavirus-1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Alphacoronavirus 1" ; rdfs:subClassOf obo:NCBITaxon_2501931 . obo:NCBITaxon_694002 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:156439" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Coronavirus group 2", "Group 2 species" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Coronavirus" ; a owl:Class ; rdfs:label "Betacoronavirus" ; rdfs:subClassOf obo:NCBITaxon_2501931 . obo:NCBITaxon_694009 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:227859", "NCBITaxon:311178" ; oboInOwl:hasBroadSynonym "HCoV-SARS", "SARS", "SARSr-CoV", "SARSrCoV" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Human coronavirus (strain SARS)", "SARS-like coronavirus", "SARS-related coronavirus" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Severe acute respiratory syndrome-related coronavirus" ; rdfs:subClassOf obo:NCBITaxon_694002 . obo:NCBITaxon_70796 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Tremovirus A" ; rdfs:subClassOf obo:NCBITaxon_2946633 . obo:NCBITaxon_70999 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "kissing bugs" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Triatominae" ; rdfs:subClassOf obo:NCBITaxon_33340 . obo:NCBITaxon_712 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10843050", "PMID:15280320", "PMID:15388716", "PMID:17220461", "PMID:2223605", "PMID:29923825" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Pasteurellaceae" ; rdfs:subClassOf obo:NCBITaxon_1236 . obo:NCBITaxon_715 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1847295" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Haemophilus pleuropneumoniae" ; a owl:Class ; rdfs:label "Actinobacillus pleuropneumoniae" ; rdfs:subClassOf obo:NCBITaxon_712 . obo:NCBITaxon_7164 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Anopheles" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Anopheles " ; rdfs:subClassOf obo:NCBITaxon_33340 . obo:NCBITaxon_72273 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Thiomicrospira group", "Thiothrix/Francisella group" ; a owl:Class ; rdfs:label "Thiotrichales" ; rdfs:subClassOf obo:NCBITaxon_1236 . obo:NCBITaxon_724 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:1736960" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Haemophilus" ; rdfs:subClassOf obo:NCBITaxon_712 . obo:NCBITaxon_727 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacterium influenzae", "Coccobacillus pfeifferi", "Haemophilus meningitidis", "Influenza-bacillus", "Mycobacterium influenzae" ; a owl:Class ; rdfs:label "Haemophilus influenzae" ; rdfs:subClassOf obo:NCBITaxon_724 . obo:NCBITaxon_731 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:163489", "NCBITaxon:214923" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:13130032", "PMID:4333932" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Haemophilus agni", "Haemophilus ovis", "Haemophilus somnifer", "Haemophilus somnus", "Hemophilus agni", "Histophilus ovis" ; a owl:Class ; rdfs:label "Histophilus somni" ; rdfs:subClassOf obo:NCBITaxon_712 . obo:NCBITaxon_738 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:5821848" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Haemophilus parasuis" ; a owl:Class ; rdfs:label "Glaesserella parasuis" ; rdfs:subClassOf obo:NCBITaxon_712 . obo:NCBITaxon_747 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:15184562" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacterium multocidum", "Micrococcus gallicidus", "Pasteurella cholerae-gallinarum", "Pasteurella gallicida" ; a owl:Class ; rdfs:label "Pasteurella multocida" ; rdfs:subClassOf obo:NCBITaxon_712 . obo:NCBITaxon_75985 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:746" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10028248", "PMID:8782683" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Pasteurella haemolytica Newsom and Cross 1932 (Approved Lists 1980)" ; a owl:Class ; rdfs:label "Mannheimia haemolytica" ; rdfs:subClassOf obo:NCBITaxon_712 . obo:NCBITaxon_766 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11760958", "PMID:8240958" ; oboInOwl:hasExactSynonym "rickettsias" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "alpha-1 proteobacteria" ; a owl:Class ; rdfs:label "Rickettsiales" ; rdfs:subClassOf obo:NCBITaxon_28211 . obo:NCBITaxon_76803 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Arteriviridae" ; rdfs:subClassOf obo:NCBITaxon_76804 . obo:NCBITaxon_76804 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Nidovirales" ; rdfs:subClassOf obo:NCBITaxon_2732506 . obo:NCBITaxon_77054 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:61430" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Theileria hirci" ; a owl:Class ; rdfs:label "Theileria lestoquardi" ; rdfs:subClassOf obo:NCBITaxon_5873 . obo:NCBITaxon_7742 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_clade ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Vertebrata", "vertebrates" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "vertebrates" ; a owl:Class ; rdfs:label "Vertebrata " ; rdfs:subClassOf obo:NCBITaxon_33213 . obo:NCBITaxon_777 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:9226923" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Rickettsia burneti", "Rickettsia diaporica" ; a owl:Class ; rdfs:label "Coxiella burnetii" ; rdfs:subClassOf obo:NCBITaxon_1236 . obo:NCBITaxon_780 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10939649", "PMID:11491333", "PMID:14662925", "PMID:9103608" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Rickettsia" ; rdfs:subClassOf obo:NCBITaxon_766 . obo:NCBITaxon_7898 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_superclass ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "fish", "fishes", "ray-finned fishes" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Actinopterygi", "Osteichthyes", "bony fishes" ; a owl:Class ; rdfs:label "Actinopterygii" ; rdfs:subClassOf obo:NCBITaxon_117571 . obo:NCBITaxon_79668 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Clostridium perfringens C" ; rdfs:subClassOf obo:NCBITaxon_1502 . obo:NCBITaxon_7995 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "catfishes" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Siluriformes" ; rdfs:subClassOf obo:NCBITaxon_186625 . obo:NCBITaxon_8015 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1", "PMID:15062801" ; oboInOwl:hasExactSynonym "salmonids" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Salmonidae" ; rdfs:subClassOf obo:NCBITaxon_1489388 . obo:NCBITaxon_8022 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:1311475" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "rainbow trout" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Oncorhynchus nerka mykiss", "Parasalmo mykiss", "Salmo mykiss" ; a owl:Class ; rdfs:label "Oncorhynchus mykiss" ; rdfs:subClassOf obo:NCBITaxon_504568 . obo:NCBITaxon_80840 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:11", "PMID:16403855" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Burkholderia/Oxalobacter/Ralstonia group" ; a owl:Class ; rdfs:label "Burkholderiales" ; rdfs:subClassOf obo:NCBITaxon_28216 . obo:NCBITaxon_810 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:83553" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319462", "PMID:11211265", "PMID:21048221", "PMID:21048222", "PMID:23620152", "PMID:25618261", "PMID:9103632", "PMID:9103637" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "\"Prowazekia\" Coles 1953", "Bedsonia", "Chlamydophila", "Miyagawanella", "Rakeia", "Rickettsiaformis" ; a owl:Class ; rdfs:label "Chlamydia" ; rdfs:subClassOf obo:NCBITaxon_2 . obo:NCBITaxon_813 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10192388", "PMID:10319462", "PMID:8102247", "PMID:8347519" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Chlamydozoon trachomatis", "Rickettsia trachomae", "Rickettsia trachomatis" ; a owl:Class ; rdfs:label "Chlamydia trachomatis" ; rdfs:subClassOf obo:NCBITaxon_810 . obo:NCBITaxon_83334 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_serotype ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Escherichia coli O157:H7" ; rdfs:subClassOf obo:NCBITaxon_562 . obo:NCBITaxon_83554 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:812" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319462", "PMID:12807198", "PMID:8102247", "PMID:8347519" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Chlamydophila psittaci", "Chlamydozoon psittaci", "Ehrlichia psittaci", "Rickettsia psittaci", "Rickettsiaformis psittacosis" ; a owl:Class ; rdfs:label "Chlamydia psittaci" ; rdfs:subClassOf obo:NCBITaxon_810 . obo:NCBITaxon_83555 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319462", "PMID:12807198", "PMID:25618261" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Chlamydia psittaci (Lillie 1930) Page 1968", "Chlamydia psittaci serotype 1", "Chlamydophila abortus" ; a owl:Class ; rdfs:label "Chlamydia abortus" ; rdfs:subClassOf obo:NCBITaxon_810 . obo:NCBITaxon_83558 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:811" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319462", "PMID:8102247", "PMID:8347519" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Chlamydophila pneumoniae" ; a owl:Class ; rdfs:label "Chlamydia pneumoniae" ; rdfs:subClassOf obo:NCBITaxon_810 . obo:NCBITaxon_83560 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319462" ; oboInOwl:hasExactSynonym "agent of mouse pneumonitis" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Chlamydia trachomatis MoPn" ; a owl:Class ; rdfs:label "Chlamydia muridarum" ; rdfs:subClassOf obo:NCBITaxon_810 . obo:NCBITaxon_836 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:11", "PMID:15774632", "PMID:24158948", "PMID:25481042", "PMID:8186083", "PMID:8590687" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Porphyromonas" ; rdfs:subClassOf obo:NCBITaxon_976 . obo:NCBITaxon_85007 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasAlternativeId "NCBITaxon:1761" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11837321", "PMID:1736962", "PMID:19244447", "PMID:31157615" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Corynebacteriales", "Corynebacteriales Goodfellow and Jones 2015", "Corynebacterineae", "Mycobacteriales Janke 1924 (Approved Lists 1980)" ; a owl:Class ; rdfs:label "Mycobacteriales" ; rdfs:subClassOf obo:NCBITaxon_1783272 . obo:NCBITaxon_85708 obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "PCV2" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Porcine circovirus Type II", "Porcine circovirus type 2", "Porcine circovirus-2" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Porcine circovirus 2" ; rdfs:subClassOf obo:NCBITaxon_2732092 . obo:NCBITaxon_8782 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "birds" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "avian", "birds" ; a owl:Class ; rdfs:label "Aves" ; rdfs:subClassOf obo:NCBITaxon_32561 . obo:NCBITaxon_8825 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_infraclass ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Neognathae" ; rdfs:subClassOf obo:NCBITaxon_8782 . obo:NCBITaxon_8835 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "ducks" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Anas" ; rdfs:subClassOf obo:NCBITaxon_1549675 . obo:NCBITaxon_9005 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasAlternativeId "NCBITaxon:9099" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "turkeys" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Phasianidae" ; rdfs:subClassOf obo:NCBITaxon_1549675 . obo:NCBITaxon_90062 obo:IAO_0000412 ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Leptospira interrogans serovar Icterohaemorrhagiae" ; rdfs:subClassOf obo:NCBITaxon_173 . obo:NCBITaxon_9031 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "Gallus domesticus", "bantam", "chicken", "chickens" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Gallus gallus domesticus", "Phasianus gallus" ; a owl:Class ; rdfs:label "Gallus gallus" ; rdfs:subClassOf obo:NCBITaxon_9005 . obo:NCBITaxon_90370 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:41530", "NCBITaxon:601", "NCBITaxon:72667" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10319519", "PMID:10758910", "PMID:15653930", "PMID:16558776", "PMID:9336938" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus typhi", "Bacterium (subgen. Eberthella) typhi", "Salmonella choleraesuis serovar Typhi", "Salmonella choleraesuis typhi", "Salmonella enterica ser. typhi", "Salmonella enterica serotype Typhi", "Salmonella enterica serovar Typhi", "Salmonella typhi" ; a owl:Class ; rdfs:label "Salmonella enterica subsp. enterica serovar Typhi" ; rdfs:subClassOf obo:NCBITaxon_59201 . obo:NCBITaxon_90371 obo:IAO_0000412 ; oboInOwl:hasAlternativeId "NCBITaxon:41532", "NCBITaxon:59210", "NCBITaxon:602" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:10758910", "PMID:15653930", "PMID:9336938" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus typhimurium", "Salmonella choleraesuis serotype typhimurium", "Salmonella enterica 1,4,[5],12,:i:1,2", "Salmonella enterica ser. typhimurium", "Salmonella enterica serotype Typhimurium", "Salmonella enterica serovar Typhimurium", "Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:1,2", "Salmonella typhi-murium", "Salmonella typhimurium" ; a owl:Class ; rdfs:label "Salmonella enterica subsp. enterica serovar Typhimurium" ; rdfs:subClassOf obo:NCBITaxon_59201 . obo:NCBITaxon_9103 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "common turkey", "turkey", "wild turkey" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Meleagris gallopavo" ; rdfs:subClassOf obo:NCBITaxon_9005 . obo:NCBITaxon_91061 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_class ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bacillus/Lactobacillus/Streptococcus group", "Firmibacteria" ; a owl:Class ; rdfs:label "Bacilli" ; rdfs:subClassOf obo:NCBITaxon_1239 . obo:NCBITaxon_91347 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:11", "PMID:27620848" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Enterobacteriaceae and related endosymbionts", "Enterobacteriaceae group", "Enterobacteriales", "gamma-3 proteobacteria" ; a owl:Class ; rdfs:label "Enterobacterales" ; rdfs:subClassOf obo:NCBITaxon_1236 . obo:NCBITaxon_91561 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "whales, hippos, ruminants, pigs, camels etc." ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Cetartiodactyla", "even-toed ungulates" ; a owl:Class ; rdfs:label "Artiodactyla" ; rdfs:subClassOf obo:NCBITaxon_314145 . obo:NCBITaxon_9224 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "parrot", "parrots" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Psittacidae" ; rdfs:subClassOf obo:NCBITaxon_8825 . obo:NCBITaxon_94063 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Leptospira sp. Pomona" ; rdfs:subClassOf obo:NCBITaxon_171 . obo:NCBITaxon_9443 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "primate" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Primata", "primates" ; a owl:Class ; rdfs:label "Primates" ; rdfs:subClassOf obo:NCBITaxon_314146 . obo:NCBITaxon_9479 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_parvorder ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "New World monkeys", "monkey", "monkeys" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Platyrrhini" ; rdfs:subClassOf obo:NCBITaxon_314293 . obo:NCBITaxon_950 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11760958", "PMID:1736961", "PMID:7537065" ; oboInOwl:hasExactSynonym "Potomac horse fever agent", "equine monocytic ehrlichiosis agent" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Ehrlichia risticii" ; a owl:Class ; rdfs:label "Neorickettsia risticii" ; rdfs:subClassOf obo:NCBITaxon_766 . obo:NCBITaxon_9526 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_parvorder ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Catarrhini" ; rdfs:subClassOf obo:NCBITaxon_314293 . obo:NCBITaxon_9534 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "African green monkey", "African green monkeys", "grivet", "savanah monkey" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Cercopithecus aethiops", "Ceropithecus aethiops", "Simia aethiops" ; a owl:Class ; rdfs:label "Chlorocebus aethiops" ; rdfs:subClassOf obo:NCBITaxon_9526 . obo:NCBITaxon_9606 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "human" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Homo sapiens" ; rdfs:subClassOf obo:NCBITaxon_9526 . obo:NCBITaxon_9608 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "dog, coyote, wolf, fox" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canidae" ; rdfs:subClassOf obo:NCBITaxon_379584 . obo:NCBITaxon_9611 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canis" ; rdfs:subClassOf obo:NCBITaxon_9608 . obo:NCBITaxon_9612 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "gray wolf", "grey wolf" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Canis lupus" ; rdfs:subClassOf obo:NCBITaxon_9611 . obo:NCBITaxon_9615 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subspecies ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "dog", "dogs" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Canis canis", "Canis domesticus", "Canis familiaris" ; a owl:Class ; rdfs:label "Canis lupus familiaris" ; rdfs:subClassOf obo:NCBITaxon_9612 . obo:NCBITaxon_9625 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasAlternativeId "NCBITaxon:68731", "NCBITaxon:9609" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Fennecus" ; a owl:Class ; rdfs:label "Vulpes" ; rdfs:subClassOf obo:NCBITaxon_9608 . obo:NCBITaxon_9654 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "northern raccoon", "raccoon" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Ursus lotor" ; a owl:Class ; rdfs:label "Procyon lotor" ; rdfs:subClassOf obo:NCBITaxon_3072906 . obo:NCBITaxon_9669 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subspecies ; oboInOwl:hasAlternativeId "NCBITaxon:77150" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "black ferret", "domestic ferret", "ferret" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Mustela furo" ; a owl:Class ; rdfs:label "Mustela putorius furo" ; rdfs:subClassOf obo:NCBITaxon_3072906 . obo:NCBITaxon_9682 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Felis" ; rdfs:subClassOf obo:NCBITaxon_33554 . obo:NCBITaxon_9685 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:36475" ; oboInOwl:hasDbXref "GC_ID:1", "PMID:17600185", "PMID:8581300", "PMID:8603894" ; oboInOwl:hasExactSynonym "cat", "cats", "domestic cat" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Felis domesticus", "Felis silvestris catus" ; a owl:Class ; rdfs:label "Felis catus" ; rdfs:subClassOf obo:NCBITaxon_9682 . obo:NCBITaxon_976 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_phylum ; oboInOwl:hasAlternativeId "NCBITaxon:171554" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11541229", "PMID:11542017", "PMID:28066339" ; oboInOwl:hasExactSynonym "BCF group", "Bacteroides-Cytophaga-Flexibacter group", "CFB group", "Cytophaga-Flexibacter-Bacteroides phylum" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "\"Bacteroidota\" Whitman et al. 2018", "Bacteroidetes", "CFB group bacteria", "Sphingobacteria" ; a owl:Class ; rdfs:label "Bacteroidota" ; rdfs:subClassOf obo:NCBITaxon_2 . obo:NCBITaxon_9768 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "sei whale" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Balaenoptera borealis" ; rdfs:subClassOf obo:NCBITaxon_91561 . obo:NCBITaxon_9788 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "horses" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Equidae" ; rdfs:subClassOf obo:NCBITaxon_314145 . obo:NCBITaxon_9796 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "domestic horse", "equine", "horse" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Equus przewalskii f. caballus", "Equus przewalskii forma caballus" ; a owl:Class ; rdfs:label "Equus caballus" ; rdfs:subClassOf obo:NCBITaxon_9788 . obo:NCBITaxon_9823 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "pig", "pigs", "swine", "wild boar" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Sus scrofa" ; rdfs:subClassOf obo:NCBITaxon_91561 . obo:NCBITaxon_9850 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "deer" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Cervidae" ; rdfs:subClassOf obo:NCBITaxon_35500 . obo:NCBITaxon_9895 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_family ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bovidae" ; rdfs:subClassOf obo:NCBITaxon_35500 . obo:NCBITaxon_9900 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Bison" ; rdfs:subClassOf obo:NCBITaxon_27592 . obo:NCBITaxon_9901 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "American bison", "Bison" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bos (Bison) bison", "Bos bison" ; a owl:Class ; rdfs:label "Bison bison" ; rdfs:subClassOf obo:NCBITaxon_9900 . obo:NCBITaxon_9913 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:272461" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "bovine", "cattle", "cow", "dairy cow", "domestic cattle", "domestic cow", "ox", "oxen" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Bos bovis", "Bos primigenius taurus" ; a owl:Class ; rdfs:label "Bos taurus" ; rdfs:subClassOf obo:NCBITaxon_27592 . obo:NCBITaxon_9925 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:57076" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "domestic goat", "goat", "goats" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Capra aegagrus hircus" ; a owl:Class ; rdfs:label "Capra hircus" ; rdfs:subClassOf obo:NCBITaxon_9963 . obo:NCBITaxon_9935 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_genus ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Ovis" ; rdfs:subClassOf obo:NCBITaxon_9963 . obo:NCBITaxon_9940 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:9936" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "domestic sheep", "lambs", "sheep", "wild sheep" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Ovis ammon aries", "Ovis orientalis aries", "Ovis ovis" ; a owl:Class ; rdfs:label "Ovis aries" ; rdfs:subClassOf obo:NCBITaxon_9935 . obo:NCBITaxon_996 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:29531" ; oboInOwl:hasDbXref "GC_ID:11", "PMID:11594628", "PMID:16560903", "PMID:29593693" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Chondrococcus columnaris", "Cytophaga columnaris", "Flavobacterium columnare (Bernardet and Grimont 1989) Bernardet et al. 1996", "Flexibacter columnaris", "Flexibacter columnaris (ex Davis 1922) Bernardet and Grimont 1989" ; a owl:Class ; rdfs:label "Flavobacterium columnare" ; rdfs:subClassOf obo:NCBITaxon_200644 . obo:NCBITaxon_9963 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_subfamily ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; a owl:Class ; rdfs:label "Caprinae" ; rdfs:subClassOf obo:NCBITaxon_9895 . obo:NCBITaxon_9986 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_species ; oboInOwl:hasAlternativeId "NCBITaxon:34833", "NCBITaxon:9985" ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "European rabbit", "Japanese white rabbit", "domestic rabbit", "rabbit", "rabbits" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "Lepus cuniculus" ; a owl:Class ; rdfs:label "Oryctolagus cuniculus" ; rdfs:subClassOf obo:NCBITaxon_314147 . obo:NCBITaxon_9989 obo:IAO_0000412 ; ncbitaxon:has_rank obo:NCBITaxon_order ; oboInOwl:hasDbXref "GC_ID:1" ; oboInOwl:hasExactSynonym "rodent" ; oboInOwl:hasOBONamespace "ncbi_taxonomy" ; oboInOwl:hasRelatedSynonym "rodents" ; a owl:Class ; rdfs:label "Rodentia" ; rdfs:subClassOf obo:NCBITaxon_314147 . obo:OAE_0000001 obo:IAO_0000115 "a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event." ; obo:IAO_0000116 "Melanie Courtot and YH: More work is needed on how to restrict the scope of a term to be an 'adverse event', notably regarding temporal association. When is an appropirate time interval between a medical intervention and an adverse event observed? One week, one month, one year, or a lifetime? For some well-studied medical interventions (e.g., administration of many vaccines or drugs), we probably have a general idea. For many new interventions, we don't know much. In OAE, this issue is associated with defining the 'adverse event incubation time'.", "YH: An adverse event is a process that has specified output of some adverse medical outcome (e.g., symptom, sign or accident) after a medical intervention (or process) (e.g., administration of drug or vaccine). The medical intervention can be an administration of a drug, a vaccine (i.e., vaccination), or a special nutritional product (for example, dietary supplement, infant formula, medical food), surgery, or usage of a medical device.", "YH: An adverse event is possibly induced by the medical intervention. It can be caused by the medical intervention, or may not be caused by the medical intervention. One ultimate goal (or the goal in clinics) of study adverse events is to assess if the adverse event outcome is due to the medical intervention.", """YH: In development of OAE, we initially use vaccine adverse event as our use case. A vaccine adverse event is associated with a vaccination (i.e. a medical intervention), regardless of whether it is considered vaccine-related, and includes any side effect, injury, toxicity, or sensitivity reaction or significant failure of immunization (i.e., a pharmacologic action). Ref: Baylor NW and Midthum K. Regulation and testing of vaccines. In: Vaccines (Editors: Plotkin S, Orenstein W, and Offit P). 2008. p1623.""", """YH: The current term 'adverse event' is different from the term definition shown in our paper: He Y, Xiang Z, Sarntivijai S, Toldo L, Ceusters W. OAE: a realism-based biomedical ontology for the representation of adverse events. Adverse Event Representation Workshop, International Conference on Biomedical Ontologies (ICBO), University at Buffalo, NY, July 26-30, 2011. Full lenghth conference proceeding paper. We made the name changing in order to make OAE cover the broader sense of the 'adverse event' which does not assume definite causal effect between an adverse event and a medical intervention. In current definition, the adverse event emphasizes the time association and assumes a likelihood of such a causal association. This term 'adverse event' is stil under the OGMS:pathological bodily process. The 'adverse event' defined in the above paper has now been changed to a new term: 'causal adverse event'. See more information in the new publication: Yongqun He Y, Sirarat Sarntivijai, Yu Lin, Zuoshuang Xiang, Abra Guo, Shelley Zhang, Desikan Jagannathan, Luca Toldo, Cui Tao and Barry Smith. OAE: The Ontology of Adverse Events. Journal of Biomedical Semantics. 2014, 5:29 doi:10.1186/2041-1480-5-29. PMID: 25093068.PMCID: PMC4120740.""", "YH: The main scope of OAE includes: (1) represent terms and relations in the area of adverse events, (2) assess possible associations between an adverse event and a medical intervention, particularly, identify any causal effect of a medical intervention to an adverse event; and (2) understand the mechanism (including molecular mechanisms) of causal adverse events.", "YH: There has been discussion regarding whether the term 'side effect' is an alternative term for 'adverse event'. In AERO, the term 'AERO:adverse event' represents a subset of those adverse events for which causality has been established. In OAE, an adverse event for which causality has been established is called 'causal adverse event'." ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000118 "AE", "adverse reaction" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Adverse_event", "WEB: http://www.fda.gov/Safety/MedWatch/HowToReport/ucm053087.htm", "WEB: http://www.ncbi.nlm.nih.gov/pubmed/25093068" ; obo:IAO_0000412 ; a owl:Class ; rdfs:comment "The OAE official website is: http://www.oae-ontology.org/." ; rdfs:label "adverse event" ; rdfs:subClassOf obo:OGMS_0000061 . obo:OAE_0000004 obo:IAO_0000115 "an adverse event that occurs after a vaccination." ; obo:IAO_0000117 "YH" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "vaccine adverse event" ; rdfs:subClassOf obo:OAE_0000001 . obo:OAE_0000055 obo:IAO_0000115 "A contraindication is a disposition that increases the risk of harm involved in using a particular drug, carrying out a medical procedure, or engaging in a particular activity such that the risk of harm exceeds a threshold. An contraindication serves as a reason to withhold a certain medical treatment." ; obo:IAO_0000117 "Yongqun He, Sirarat Sarntivijai, Mathias Brochhausen, William Hogan, ‎Philip E. Empey" ; obo:IAO_0000119 "http://en.wikipedia.org/wiki/Contraindication" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "contraindication" ; rdfs:subClassOf obo:BFO_0000016 . obo:OAE_0000097 obo:IAO_0000115 "an adverse event that is induced by a vaccination." ; obo:IAO_0000117 "YH" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "vaccine-induced adverse event" ; rdfs:subClassOf obo:OAE_0000004 . obo:OBI_0000011 obo:IAO_0000111 "planned process", "planned process"@en ; obo:IAO_0000112 "Injecting mice with a vaccine in order to test its efficacy" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A process that realizes a plan which is the concretization of a plan specification."@en ; obo:IAO_0000116 "'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)", """We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some objectives is a planned process.""" ; obo:IAO_0000117 "Bjoern Peters" ; obo:IAO_0000119 "branch derived" ; obo:IAO_0000232 "6/11/9: Edited at workshop. Used to include: is initiated by an agent", "This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "planned process"@en ; rdfs:subClassOf obo:BFO_0000015 ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Restriction ; owl:onProperty obo:RO_0000059 ; owl:someValuesFrom obo:IAO_0000104 ] ] . obo:OBI_0000014 obo:IAO_0000111 "regulator role" ; obo:IAO_0000112 "Fact sheet - Regulating the companies The role of the regulator. Ofwat is the economic regulator of the water and sewerage industry in England and Wales. http://www.ofwat.gov.uk/aptrix/ofwat/publish.nsf/Content/roleofregulator_factsheet170805"@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "a regulatory role involved with making and/or enforcing relevant legislation and governmental orders"@en ; obo:IAO_0000117 "Person:Jennifer Fostel"@en ; obo:IAO_0000118 "regulator" ; obo:IAO_0000119 "OBI"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "regulator role"@en ; rdfs:subClassOf obo:OBI_0000017 . obo:OBI_0000016 obo:IAO_0000111 "regulation-assigned role"@en ; obo:IAO_0000112 "Approval letter"@en ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "Regulation-assigned role is a regulatory role defined by legislation or governmental orders"@en ; obo:IAO_0000117 "Person: Jennifer Fostel"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "regulation-assigned role"@en ; rdfs:subClassOf obo:OBI_0000017 . obo:OBI_0000017 obo:IAO_0000111 "regulatory role"@en ; obo:IAO_0000112 "Regulatory agency, Ethics committee, Approval letter; example: Browse these EPA Regulatory Role subtopics http://www.epa.gov/ebtpages/enviregulatoryrole.html Feb 29, 2008"@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body."@en ; obo:IAO_0000117 "GROUP: Role branch"@en ; obo:IAO_0000119 "OBI, CDISC"@en ; obo:IAO_0000232 "govt agents responsible for creating regulations; proxies for enforcing regulations. CDISC definition: regulatory authorities. Bodies having the power to regulate. NOTE: In the ICH GCP guideline the term includes the authorities that review submitted clinical data and those that conduct inspections. These bodies are sometimes referred to as competent"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "regulatory role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:OBI_0000047 obo:IAO_0000111 "processed material"@en ; obo:IAO_0000112 "Examples include gel matrices, filter paper, parafilm and buffer solutions, mass spectrometer, tissue samples"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "Is a material entity that is created or changed during material processing."@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "processed material"@en ; rdfs:subClassOf obo:BFO_0000040 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:BFO_0000040 [ a owl:Restriction ; owl:onProperty obo:OBI_0000312 ; owl:someValuesFrom obo:OBI_0000094 ] ) ] . obo:OBI_0000067 obo:IAO_0000111 "evaluant role"@en ; obo:IAO_0000112 "When a specimen of blood is assayed for glucose concentration, the blood has the evaluant role. When measuring the mass of a mouse, the evaluant is the mouse. When measuring the time of DNA replication, the evaluant is the DNA. When measuring the intensity of light on a surface, the evaluant is the light source."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role"@en ; obo:IAO_0000116 "Role call - 17nov-08: JF and MC think an evaluant role is always specified input of a process. Even in the case where we have an assay taking blood as evaluant and outputting blood, the blood is not the specified output at the end of the assay (the concentration of glucose in the blood is)"@en, "examples of features that could be described in an evaluant: quality.... e.g. \"contains 10 pg/ml IL2\", or \"no glucose detected\")"@en ; obo:IAO_0000117 "GROUP: Role Branch" ; obo:IAO_0000119 "OBI" ; obo:IAO_0000232 "Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "evaluant role"@en ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:BFO_0000040 ], [ a owl:Restriction ; owl:allValuesFrom obo:OBI_0000070 ; owl:onProperty obo:BFO_0000054 ] . obo:OBI_0000070 obo:IAO_0000111 "assay"@en ; obo:IAO_0000112 "Assay the wavelength of light emitted by excited Neon atoms. Count of geese flying over a house." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A planned process that has the objective to produce information about a material entity (the evaluant) by examining it."@en ; obo:IAO_0000116 "12/3/12: BP: the reference to the 'physical examination' is included to point out that a prediction is not an assay, as that does not require physical examiniation.", "Discussion on OBI call 2023-05-01 resulted in an agreement to revise the textual definition of 'assay'. https://github.com/obi-ontology/obi/issues/1683." ; obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ; obo:IAO_0000118 "measuring"@en, "scientific observation"@en ; obo:IAO_0000119 "OBI branch derived"@en ; obo:IAO_0000412 ; obo:OBI_0001847 "study assay" ; obo:OBI_9991118 "any method" ; a owl:Class ; rdfs:label "assay"@en ; rdfs:subClassOf obo:OBI_0000011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom obo:OBI_0000067 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:BFO_0000040 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000067 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:IAO_0000027 [ a owl:Restriction ; owl:onProperty obo:IAO_0000136 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:BFO_0000040 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000067 ] ) ] ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000441 ] . obo:OBI_0000086 obo:IAO_0000111 "reagent role" ; obo:IAO_0000112 "Buffer, dye, a catalyst, a solvating agent."@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer."@en ; obo:IAO_0000117 "PERSON:Matthew Brush"@en ; obo:IAO_0000118 "reagent" ; obo:IAO_0000119 "PERSON:Matthew Brush" ; obo:IAO_0000232 """Feb 10, 2009. changes after discussion at OBI Consortium Workshop Feb 2-6, 2009. accepted as core term. May 28 2013. Updated definition taken from ReO based on discussions initiated in Philly 2011 workshop. Former defnition described a narrower view of reagents in chemistry that restricts bearers of the role to be chemical entities (\"a role played by a molecular entity used to produce a chemical reaction to detect, measure, or produce other substances\"). Updated definition allows for broader view of reagents in the domain of biomedical research to include larger materials that have parts that participate chemically in a molecular reaction or interaction.""" ; obo:IAO_0000412 ; a owl:Class ; rdfs:comment """(copied from ReO) Reagents are distinguished from instruments or devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in or have parts that participate in some chemical interaction or reaction during their intended participation in some technique. By contrast, instruments do not participate in a chemical reaction/interaction during the technique. Reagents are distinguished from study subjects/evaluants in that study subjects and evaluants are that about which conclusions are drawn and knowledge is sought in an investigation - while reagents, by definition, are not. It should be noted, however, that reagent and study subject/evaluant roles can be borne by instances of the same type of material entity - but a given instance will realize only one of these roles in the execution of a given assay or technique. For example, taq polymerase can bear a reagent role or an evaluant role. In a DNA sequencing assay aimed at generating sequence data about some plasmid, the reagent role of the taq polymerase is realized. In an assay to evaluate the quality of the taq polymerase itself, the evaluant/study subject role of the taq is realized, but not the reagent role since the taq is the subject about which data is generated. In regard to the statement that reagents are 'distinct' from the specified outputs of a technique, note that a reagent may be incorporated into a material output of a technique, as long as the IDENTITY of this output is distinct from that of the bearer of the reagent role. For example, dNTPs input into a PCR are reagents that become part of the material output of this technique, but this output has a new identity (ie that of a 'nucleic acid molecule') that is distinct from the identity of the dNTPs that comprise it. Similarly, a biotin molecule input into a cell labeling technique are reagents that become part of the specified output, but the identity of the output is that of some modified cell specimen which shares identity with the input unmodified cell specimen, and not with the biotin label. Thus, we see that an important criteria of 'reagent-ness' is that it is a facilitator, and not the primary focus of an investigation or material processing technique (ie not the specified subject/evaluant about which knowledge is sought, or the specified output material of the technique).""" ; rdfs:label "reagent role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:OBI_0000094 obo:IAO_0000111 "material processing" ; obo:IAO_0000112 "A cell lysis, production of a cloning vector, creating a buffer." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A planned process which results in physical changes in a specified input material"@en ; obo:IAO_0000117 "PERSON: Bjoern Peters"@en, "PERSON: Frank Gibson", "PERSON: Jennifer Fostel", "PERSON: Melanie Courtot", "PERSON: Philippe Rocca Serra" ; obo:IAO_0000118 "material transformation"@en ; obo:IAO_0000119 "OBI branch derived"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "material processing"@en ; rdfs:subClassOf obo:OBI_0000011, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:OBI_0000047 ], [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000040 ; owl:onProperty obo:OBI_0000293 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000456 ] . obo:OBI_0000181 obo:IAO_0000111 "population"@en ; obo:IAO_0000112 "PMID12564891. Environ Sci Technol. 2003 Jan 15;37(2):223-8. Effects of historic PCB exposures on the reproductive success of the Hudson River striped bass population."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area"@en ; obo:IAO_0000116 """1/28/2013, BP, on the call it was raised that we may want to switch to an external ontology for all populatin terms: http://code.google.com/p/popcomm-ontology/""" ; obo:IAO_0000117 "PERSON: Philippe Rocca-Serra"@en ; obo:IAO_0000119 "adapted from Oxford English Dictionnary"@en ; obo:IAO_0000232 "rem1: collection somehow always involve a selection process"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "population"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:OBI_0000237 obo:IAO_0000111 "antigen role" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "A role of a material entity that is being recognized in whole or in part by receptors of the immune system such as antibodies or T cell receptors."@en ; obo:IAO_0000116 "An antigen is a substance that prompts the generation of antibodies and can cause an immune response. Wikipedia http://en.wikipedia.org/wiki/Antigen. In the strict sense, immunogens are those substances that elicit a response from the immune system, whereas antigens are defined as substances that bind to specific antibodies. Not all antigens produce an immunogenic response, but all immunogens are antigens" ; obo:IAO_0000117 "Role Branch"@en ; obo:IAO_0000119 "OBI" ; obo:IAO_0000232 "9Mar09 waiting for discussion with immunology terms" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "antigen role"@en ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:allValuesFrom obo:GO_0006955 ; owl:onProperty obo:BFO_0000054 ] . obo:OBI_0000245 obo:IAO_0000111 "organization"@en ; obo:IAO_0000112 "PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members."@en ; obo:IAO_0000116 """BP: The definition summarizes long email discussions on the OBI developer, roles, biomaterial and denrie branches. It leaves open if an organization is a material entity or a dependent continuant, as no consensus was reached on that. The current placement as material is therefore temporary, in order to move forward with development. Here is the entire email summary, on which the definition is based: 1) there are organization_member_roles (president, treasurer, branch editor), with individual persons as bearers 2) there are organization_roles (employer, owner, vendor, patent holder) 3) an organization has a charter / rules / bylaws, which specify what roles there are, how they should be realized, and how to modify the charter/rules/bylaws themselves. It is debatable what the organization itself is (some kind of dependent continuant or an aggregate of people). This also determines who/what the bearer of organization_roles' are. My personal favorite is still to define organization as a kind of 'legal entity', but thinking it through leads to all kinds of questions that are clearly outside the scope of OBI. Interestingly enough, it does not seem to matter much where we place organization itself, as long as we can subclass it (University, Corporation, Government Agency, Hospital), instantiate it (Affymetrix, NCBI, NIH, ISO, W3C, University of Oklahoma), and have it play roles. This leads to my proposal: We define organization through the statements 1 - 3 above, but without an 'is a' statement for now. We can leave it in its current place in the is_a hierarchy (material entity) or move it up to 'continuant'. We leave further clarifications to BFO, and close this issue for now."""@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg", "PERSON: Bjoern Peters", "PERSON: Philippe Rocca-Serra", "PERSON: Susanna Sansone" ; obo:IAO_0000119 "GROUP: OBI" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "organization"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:OBI_0000272 obo:IAO_0000111 "protocol"@en ; obo:IAO_0000112 "PCR protocol, has objective specification, amplify DNA fragment of interest, and has action specification describes the amounts of experimental reagents used (e..g. buffers, dNTPS, enzyme), and the temperature and cycle time settings for running the PCR."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process."@en ; obo:IAO_0000117 "PlanAndPlannedProcess Branch"@en ; obo:IAO_0000119 "OBI branch derived + wikipedia (http://en.wikipedia.org/wiki/Protocol_%28natural_sciences%29)"@en ; obo:IAO_0000412 ; obo:OBI_0001847 "study protocol" ; a owl:Class ; rdfs:label "protocol"@en ; rdfs:subClassOf obo:IAO_0000104 . obo:OBI_0000274 obo:IAO_0000111 "adding a material entity into a target" ; obo:IAO_0000112 "Injecting a drug into a mouse. Adding IL-2 to a cell culture. Adding NaCl into water." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'."@en ; obo:IAO_0000116 "Class was renamed from 'administering substance', as this is commonly used only for additions into organisms." ; obo:IAO_0000117 "BP" ; obo:IAO_0000119 "branch derived" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "adding a material entity into a target"@en ; rdfs:subClassOf obo:OBI_0000652, [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom obo:OBI_0000319 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom obo:OBI_0000444 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:BFO_0000040 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000319 ] [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:BFO_0000040 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000444 ] ) ] ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000434 ] . obo:OBI_0000281 obo:IAO_0000111 "intraperitoneal injection" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe" ; obo:IAO_0000117 "BP" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "intraperitoneal injection"@en ; rdfs:subClassOf obo:OBI_0000426, obo:OBI_0000429, [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000434 ] . obo:OBI_0000293 obo:IAO_0000111 "has_specified_input", "has_specified_input"@en ; obo:IAO_0000112 "see is_input_of example_of_usage"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "The inverse property of is_specified_input_of"@en ; obo:IAO_0000116 "8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works." ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bjoern Peters", "PERSON: Larry Hunter", "PERSON: Melanie Coutot" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has_specified_input"@en ; rdfs:subPropertyOf obo:RO_0000057 ; owl:equivalentProperty [ owl:inverseOf obo:OBI_0000295 ] . obo:OBI_0000295 obo:IAO_0000111 "is_specified_input_of" ; obo:IAO_0000112 "some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en, "PERSON:Bjoern Peters" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "is_specified_input_of"@en ; rdfs:subPropertyOf obo:RO_0000056 . obo:OBI_0000299 obo:IAO_0000111 "has_specified_output", "has_specified_output"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "The inverse property of is_specified_output_of"@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Bjoern Peters", "PERSON: Larry Hunter", "PERSON: Melanie Courtot" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has_specified_output"@en ; rdfs:subPropertyOf obo:RO_0000057 ; owl:equivalentProperty [ owl:inverseOf obo:OBI_0000312 ] . obo:OBI_0000304 obo:IAO_0000111 "is_manufactured_by"@en ; obo:IAO_0000112 "http://www.affymetrix.com/products/arrays/specific/hgu133.affx is_manufactered_by http://www.affymetrix.com/ (if we decide to use these URIs for the actual entities)"@en ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the \"Manufacturer Role\", and those people/and or machines were members or of directed by the organization to do this."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en, "Liju Fan"@en ; obo:IAO_0000118 "has_make"@en, "has_manufacturer"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "is_manufactured_by"@en . obo:OBI_0000312 obo:IAO_0000111 "is_specified_output_of", "is_specified_output_of"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en, "PERSON:Bjoern Peters" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "is_specified_output_of"@en ; rdfs:subPropertyOf obo:RO_0000056 . obo:OBI_0000319 obo:IAO_0000111 "material to be added role" ; obo:IAO_0000112 "drug added to a buffer contained in a tube; substance injected into an animal;" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role is added into another material entity (the target)."@en ; obo:IAO_0000117 "Role Branch" ; obo:IAO_0000119 "OBI" ; obo:IAO_0000232 "9 March 09 from discussion with PA branch" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "material to be added role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:OBI_0000383 obo:IAO_0000111 "transfer function"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A transfer function is a function to displace a material from one location to another."@en ; obo:IAO_0000117 "Bill Bug", "Daniel Schober", "Frank Gibson", "Melanie Courtot" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "transfer function"@en ; rdfs:subClassOf obo:BFO_0000034 . obo:OBI_0000417 obo:IAO_0000111 "achieves_planned_objective" ; obo:IAO_0000112 "A cell sorting process achieves the objective specification 'material separation objective'" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." ; obo:IAO_0000117 "BP, AR, PPPB branch" ; obo:IAO_0000119 "PPPB branch derived" ; obo:IAO_0000232 "modified according to email thread from 1/23/09 in accordince with DT and PPPB branch" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "achieves_planned_objective" . obo:OBI_0000422 obo:IAO_0000111 "syringe" ; obo:IAO_0000112 "Accuracy of oral liquid measuring devices: comparison of dosing cup and oral dosing syringe.Ann Pharmacother. 2008 Jan;42(1):46-52. Epub 2007 Dec 4. PMID: 18056832" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A processed material which is used to introduce or draw fluids from a material entity. A syringe is made of a piston and body. the movement of the piston in the body determines the amount/volume of fluid to inject or draw" ; obo:IAO_0000117 "Philippe Rocca-Serra" ; obo:IAO_0000119 "OBI Instrument adapted from Wikipedia" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "syringe" ; rdfs:subClassOf obo:OBI_0000968, [ a owl:Restriction ; owl:onProperty obo:RO_0000085 ; owl:someValuesFrom obo:OBI_0000383 ] . obo:OBI_0000426 obo:IAO_0000111 "injection" ; obo:IAO_0000112 "Multiple Small-Dose Injections Can Reduce the Passage of Sclerosant Foam into Deep Veins During Foam Sclerotherapy for Varicose Veins. Eur J Vasc Endovasc Surg. 2008 Oct 13. PMID: 18922712"@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "injection is process which aims at introducing a compound or a mixture into a material entity (either biological entity or instrument) by relying on devices such as syringe or injector connection, attached or forced into a vascular system (veins of an organism or tubes of a machine) or in a tissue."@en ; obo:IAO_0000117 "Philippe Rocca-Serra" ; obo:IAO_0000119 "OBI Biomaterial" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "injection"@en ; rdfs:subClassOf obo:OBI_0000274, [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000434 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf ([ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom obo:OBI_0000319 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:BFO_0000034 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:OBI_0000422 ] ) ] ] ) ] . obo:OBI_0000429 obo:IAO_0000111 "intraperitoneal administration" ; obo:IAO_0000112 "Rats were injected intraperitoneally with either rrIL-6 (250 ng/0.5 ml) or equal-volume sterile saline twice within an interval of 24 h" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "The administration of a substance into the peritoneum of an organism" ; obo:IAO_0000117 "Person:Bjoern Peters" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "intraperitoneal administration"@en ; rdfs:subClassOf obo:OBI_0000274, obo:OBI_0600007, [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000434 ] . obo:OBI_0000434 obo:IAO_0000111 "adding material objective" ; obo:IAO_0000112 "creating a mouse infected with LCM virus" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity"@en ; obo:IAO_0000117 "BP" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "adding material objective"@en ; rdfs:subClassOf obo:OBI_0000686 . obo:OBI_0000441 obo:IAO_0000111 "assay objective" ; obo:IAO_0000112 "the objective to determine the weight of a mouse." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)"@en ; obo:IAO_0000117 "PPPB branch" ; obo:IAO_0000119 "PPPB branch" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "assay objective"@en ; rdfs:subClassOf obo:IAO_0000005 . obo:OBI_0000444 obo:IAO_0000111 "target of material addition role" ; obo:IAO_0000112 "peritoneum of an animal receiving an interperitoneal injection; solution in a tube receiving additional material; location of absorbed material following a dermal application." ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A role of a material entity that is realized in an \"adding a material entity into a target\" process where the bearer of the role (the target) receives the addition of another material entity." ; obo:IAO_0000116 "From Branch discussion with BP, AR, MC -- there is a need for the recipient to interact with the administered material. for example, a tooth receiving a filling was not considered to be a target role." ; obo:IAO_0000117 "GROUP: Role Branch" ; obo:IAO_0000119 "OBI" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "target of material addition role"@en ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:BFO_0000040 ], [ a owl:Restriction ; owl:allValuesFrom obo:OBI_0000274 ; owl:onProperty obo:BFO_0000054 ] . obo:OBI_0000450 obo:IAO_0000111 "regulatory agency"@en ; obo:IAO_0000112 "The US Environmental Protection Agency" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A regulatory agency is a organization that has responsibility over or for the legislation (acts and regulations) for a given sector of the government."@en ; obo:IAO_0000117 "GROUP: OBI Biomaterial Branch" ; obo:IAO_0000119 "WEB: en.wikipedia.org/wiki/Regulator" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "regulatory agency"@en ; rdfs:subClassOf obo:OBI_0000245 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OBI_0000245 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000014 ] ) ] . obo:OBI_0000456 obo:IAO_0000111 "material transformation objective" ; obo:IAO_0000112 "The objective to create a mouse infected with LCM virus. The objective to create a defined solution of PBS." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "an objective specifiction that creates an specific output object from input materials."@en ; obo:IAO_0000117 "PERSON: Bjoern Peters", "PERSON: Frank Gibson", "PERSON: Jennifer Fostel", "PERSON: Melanie Courtot", "PERSON: Philippe Rocca-Serra" ; obo:IAO_0000118 "artifact creation objective"@en ; obo:IAO_0000119 "GROUP: OBI PlanAndPlannedProcess Branch" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "material transformation objective"@en ; rdfs:subClassOf obo:IAO_0000005 . obo:OBI_0000457 obo:IAO_0000111 "manufacturing" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A planned process with the objective to produce a processed material which will have a function for future use."@en ; obo:IAO_0000116 "A person or organization (having manufacturer role) is a participant in this process", "Manufacturing implies reproducibility and responsibility AR", "This includes a single scientist making a processed material for personal use."@en ; obo:IAO_0000117 "PERSON: Bjoern Peters", "PERSON: Frank Gibson", "PERSON: Jennifer Fostel", "PERSON: Melanie Courtot", "PERSON: Philippe Rocca-Serra" ; obo:IAO_0000119 "GROUP: OBI PlanAndPlannedProcess Branch" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "manufacturing"@en ; rdfs:subClassOf obo:OBI_0000094, [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:BFO_0000040 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:OBI_0000047 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000458 ] . obo:OBI_0000458 obo:IAO_0000111 "manufacturing objective" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "is the objective to manufacture a material of a certain function (device)"@en ; obo:IAO_0000117 "PERSON: Bjoern Peters", "PERSON: Frank Gibson", "PERSON: Jennifer Fostel", "PERSON: Melanie Courtot", "PERSON: Philippe Rocca-Serra" ; obo:IAO_0000119 "GROUP: OBI PlanAndPlannedProcess Branch" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "manufacturing objective"@en ; rdfs:subClassOf obo:OBI_0000456 . obo:OBI_0000571 obo:IAO_0000111 "manufacturer role" ; obo:IAO_0000112 "With respect to The Accuri C6 Flow Cytometer System, the organization Accuri bears the role manufacturer role. With respect to a transformed line of tissue culture cells derived by a specific lab, the lab whose personnel isolated the cll line bears the role manufacturer role. With respect to a specific antibody produced by an individual scientist, the scientist who purifies, characterizes and distributes the anitbody bears the role manufacturer role." ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process." ; obo:IAO_0000117 "GROUP: Role Branch" ; obo:IAO_0000119 "OBI" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "manufacturer role" ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:NCBITaxon_9606 obo:OBI_0000245 ) ] ], [ a owl:Restriction ; owl:allValuesFrom obo:OBI_0000457 ; owl:onProperty obo:BFO_0000054 ] . obo:OBI_0000576 obo:IAO_0000111 "scattered molecular aggregate" ; obo:IAO_0000112 "the sodium and chloride ions in a glass of salt water" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates"@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en ; obo:IAO_0000118 "Collective"@en ; obo:IAO_0000119 "Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. With inspiration from the paper Granularity, scale and collectivity: When size does and does not matter, Alan Recto, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "scattered molecular aggregate"@en ; rdfs:subClassOf obo:BFO_0000040, [ a owl:Restriction ; owl:onProperty obo:OBI_0000643 ; owl:someValuesFrom obo:CHEBI_23367 ], [ a owl:Restriction ; owl:allValuesFrom obo:CHEBI_23367 ; owl:onProperty obo:OBI_0000643 ] . obo:OBI_0000643 obo:IAO_0000111 "has grain" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car." ; obo:IAO_0000116 "Discussion in Karslruhe with, among others, Alan Rector, Stefan Schulz, Marijke Keet, Melanie Courtot, and Alan Ruttenberg. Definition take from the definition of granular parthood in the cited paper. Needs work to put into standard form"@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en ; obo:IAO_0000119 "PAPER: Granularity, scale and collectivity: When size does and does not matter, Alan Rector, Jeremy Rogers, Thomas Bittner, Journal of Biomedical Informatics 39 (2006) 333-349" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has grain" ; rdfs:subPropertyOf obo:BFO_0000051 . obo:OBI_0000652 obo:IAO_0000111 "material combination" ; obo:IAO_0000112 "Mixing two fluids. Adding salt into water. Injecting a mouse with PBS." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "is a material processing with the objective to combine two or more material entities as input into a single material entity as output." ; obo:IAO_0000116 "created at workshop as parent class for 'adding material into target', which is asymmetric, while combination encompasses all addition processes." ; obo:IAO_0000117 "bp" ; obo:IAO_0000119 "bp" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "material combination" ; rdfs:subClassOf obo:OBI_0000094, [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:BFO_0000040 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:BFO_0000040 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000686 ] . obo:OBI_0000673 obo:IAO_0000111 "statistical hypothesis test"@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test."@en ; obo:IAO_0000117 "James Malone" ; obo:IAO_0000119 "PERSON: James Malone"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "statistical hypothesis test"@en ; rdfs:subClassOf obo:OBI_0200000 ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000675 ] . obo:OBI_0000675 obo:IAO_0000111 "statistical hypothesis test objective"@en ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation." ; obo:IAO_0000117 "James Malone"@en, "Person:Helen Parkinson" ; obo:IAO_0000118 "hypothesis test objective" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Statistical_hypothesis_testing" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "statistical hypothesis test objective"@en ; rdfs:subClassOf obo:OBI_0200166 . obo:OBI_0000685 obo:IAO_0000111 "creating a mixture of molecules in solution" ; obo:IAO_0000112 "The production of PBS" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "is a process with the objective to prepare a liquid solution of one or more chemicals at desired concentrations." ; obo:IAO_0000117 "Bjoern Peters" ; obo:IAO_0000119 "PERSON: Helen Parkinson" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "creating a mixture of molecules in solution" ; rdfs:subClassOf obo:OBI_0000652, [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:BFO_0000040 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:OBI_0302729 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000456 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000686 ] . obo:OBI_0000686 obo:IAO_0000111 "material combination objective" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "is an objective to obtain an output material that contains several input materials." ; obo:IAO_0000117 "PPPB branch" ; obo:IAO_0000119 "bp" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "material combination objective" ; rdfs:subClassOf obo:OBI_0000456 . obo:OBI_0000712 obo:IAO_0000111 "pathogen challenge" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "The administration of a live pathogenic organism to a host." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "pathogen challenge" ; rdfs:subClassOf obo:OBI_0003456, [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom obo:OBI_0000725 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000319 [ a owl:Restriction ; owl:onProperty obo:RO_0000081 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000718 ] ) ] ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000444 [ a owl:Restriction ; owl:onProperty obo:RO_0000081 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000725 ] ) ] ] ) ] ] . obo:OBI_0000718 obo:IAO_0000111 "pathogen role" ; obo:IAO_0000112 "Pathogen: An agent of disease. A disease producer. The term pathogen most commonly is used to refer to infectious organisms. These include bacteria (such as staph), viruses (such as HIV), and fungi (such as yeast). Less commonly, pathogen refers to a noninfectious agent of disease such as a chemical. http://www.medterms.com/script/main/art.asp?articlekey=6383" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "pathogen role is a role which inheres in an organism and realized in the process of disease course in the organism bearing host role caused by the organism bearing pathogen role" ; obo:IAO_0000117 "GROUP: Role Branch" ; obo:IAO_0000119 "OBI" ; obo:IAO_0000232 "6 April 2009: from the Vaccine Community" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "pathogen role" ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:OBI_0100026 ], [ a owl:Restriction ; owl:allValuesFrom obo:OGMS_0000063 ; owl:onProperty obo:BFO_0000054 ] . obo:OBI_0000725 obo:IAO_0000111 "host role" ; obo:IAO_0000112 "In biology, a host is an organism that harbors a virus or parasite, or a mutual or commensal symbiont, typically providing nourishment and shelter. http://en.wikipedia.org/wiki/Host_(biology) 30 March 09" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role" ; obo:IAO_0000116 "30Mar09 virus reproducing inside a cell; bacteria causing a disease, host can be harmed or not. we want to avoid a cat sitting on my lap and an animal care technician; these are not examples or hosts; dental cares = on tooth, but part of outer layer of tooth, so covered by \"within\" in the definition" ; obo:IAO_0000117 "GROUP: Role Branch" ; obo:IAO_0000119 "30 Mar09 submitted by vaccine community", "OBI", "http://en.wikipedia.org/wiki/Host_(biology)" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "host role" ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:OBI_0100026 ] . obo:OBI_0000750 obo:IAO_0000111 "independent variable specification" ; obo:IAO_0000112 "In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, disease status is the independent variable." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled"@en ; obo:IAO_0000116 "2/2/2009 Original definition - In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled."@en, "In the Philly 2013 workshop the label was chosen to distinguish it from \"dependent variable\" as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling" ; obo:IAO_0000117 "PERSON: Alan Ruttenberg", "PERSON: Bjoern Peters", "PERSON: Chris Stoeckert" ; obo:IAO_0000118 "experimental factor", "independent variable" ; obo:IAO_0000119 "Web: http://en.wikipedia.org/wiki/Dependent_and_independent_variables" ; obo:IAO_0000232 "2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI." ; obo:IAO_0000412 ; obo:OBI_0001847 "study factor" ; a owl:Class ; rdfs:label "study design independent variable"@en ; rdfs:subClassOf obo:IAO_0000033, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:OBI_0500000 ] . obo:OBI_0000751 obo:IAO_0000111 "dependent variable specification" ; obo:IAO_0000112 "In a study in which gene expression is measured in patients between 8 month to 4 years old that have mild or severe malaria and in which the hypothesis is that gene expression in that age group is a function of disease status, the gene expression is the dependent variable." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies."@en ; obo:IAO_0000116 "2/2/2009 In the design of experiments, independent variables are those whose values are controlled or selected by the person experimenting (experimenter) to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled."@en, "In the Philly 2013 workshop the label was chosen to distinguish it from \"dependent variable\" as used in statistical modelling. See: http://en.wikipedia.org/wiki/Statistical_modeling" ; obo:IAO_0000117 "PERSON: Alan Ruttenberg", "PERSON: Bjoern Peters", "PERSON: Chris Stoeckert" ; obo:IAO_0000118 "dependent variable" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Dependent_and_independent_variables" ; obo:IAO_0000232 "2009-03-16: work has been done on this term during during the OBI workshop winter 2009 and the current definition was considered acceptable for use in OBI. If there is a need to modify thisdefinition please notify OBI." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "study design dependent variable"@en ; rdfs:subClassOf obo:IAO_0000033, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:OBI_0500000 ] . obo:OBI_0000806 obo:IAO_0000111 "material maintenance objective" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An objective specification maintains some or all of the qualities of a material over time." ; obo:IAO_0000117 "PERSON: Bjoern Peters" ; obo:IAO_0000119 "PERSON: Bjoern Peters" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "material maintenance objective" ; rdfs:subClassOf obo:IAO_0000005 . obo:OBI_0000833 obo:IAO_0000111 "objective_achieved_by" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." ; obo:IAO_0000117 "OBI" ; obo:IAO_0000119 "OBI" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "objective_achieved_by" . obo:OBI_0000835 obo:IAO_0000111 "manufacturer" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "A person or organization that has a manufacturer role." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "manufacturer" ; rdfs:subClassOf obo:BFO_0000040 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf ([ a owl:Class ; owl:unionOf (obo:NCBITaxon_9606 obo:OBI_0000245 ) ] [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000571 ] ) ] . obo:OBI_0000838 obo:IAO_0000111 "material maintenance" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "A planned process with the objective to maintain some or all of the characteristics of an input material over time." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "material maintenance" ; rdfs:subClassOf obo:OBI_0000011 ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000806 ] . obo:OBI_0000938 obo:IAO_0000111 "categorical measurement datum" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A measurement datum that is reported on a categorical scale." ; obo:IAO_0000117 "Bjoern Peters" ; obo:IAO_0000118 "nominal mesurement datum" ; obo:IAO_0000119 "Bjoern Peters" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "categorical measurement datum" ; rdfs:subClassOf obo:IAO_0000109, [ a owl:Restriction ; owl:onProperty obo:OBI_0001938 ; owl:someValuesFrom obo:OBI_0001930 ] . obo:OBI_0000968 obo:IAO_0000111 "device" ; obo:IAO_0000112 "A voltmeter is a measurement device which is intended to perform some measure function.", "An autoclave is a device that sterlizes instruments or contaminated waste by applying high temperature and pressure." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A material entity that is designed to perform a function in a scientific investigation, but is not a reagent." ; obo:IAO_0000116 """2012-12-17 JAO: In common lab usage, there is a distinction made between devices and reagents that is difficult to model. Therefore we have chosen to specifically exclude reagents from the definition of \"device\", and are enumerating the types of roles that a reagent can perform. 2013-6-5 MHB: The following clarifications are outcomes of the May 2013 Philly Workshop. Reagents are distinguished from devices that also participate in scientific techniques by the fact that reagents are chemical or biological in nature and necessarily participate in some chemical interaction or reaction during the realization of their experimental role. By contrast, devices do not participate in such chemical reactions/interactions. Note that there are cases where devices use reagent components during their operation, where the reagent-device distinction is less clear. For example: (1) An HPLC machine is considered a device, but has a column that holds a stationary phase resin as an operational component. This resin qualifies as a device if it participates purely in size exclusion, but bears a reagent role that is realized in the running of a column if it interacts electrostatically or chemically with the evaluant. The container the resin is in (“the column”) considered alone is a device. So the entire column as well as the entire HPLC machine are devices that have a reagent as an operating part. (2) A pH meter is a device, but its electrode component bears a reagent role in virtue of its interacting directly with the evaluant in execution of an assay. (3) A gel running box is a device that has a metallic lead as a component that participates in a chemical reaction with the running buffer when a charge is passed through it. This metallic lead is considered to have a reagent role as a component of this device realized in the running of a gel. In the examples above, a reagent is an operational component of a device, but the device itself does not realize a reagent role (as bearing a reagent role is not transitive across the part_of relation). In this way, the asserted disjointness between a reagent and device holds, as both roles are never realized in the same bearer during execution of an assay.""" ; obo:IAO_0000117 "PERSON: Helen Parkinson" ; obo:IAO_0000118 "instrument" ; obo:IAO_0000119 "OBI development call 2012-12-17." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "device" ; rdfs:subClassOf obo:OBI_0000047, [ a owl:Restriction ; owl:onProperty obo:OBI_0000312 ; owl:someValuesFrom obo:OBI_0000094 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000085 ; owl:someValuesFrom obo:BFO_0000034 ] . obo:OBI_0000969 obo:IAO_0000111 "dose specification" ; obo:IAO_0000112 "a protocol specifying to administer 1 ml of vaccine to a mouse" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "a directive information entity that describes the dose that will be administered to a target" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "dose specification" ; rdfs:subClassOf obo:IAO_0000033 . obo:OBI_0000984 obo:IAO_0000111 "dose" ; obo:IAO_0000112 "An organism has been injected 1ml of vaccine" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses." ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "dose" ; rdfs:subClassOf obo:IAO_0000109 . obo:OBI_0001847 obo:IAO_0000111 "ISA alternative term"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An alternative term used by the ISA tools project (http://isa-tools.org)." ; obo:IAO_0000116 """Requested by Alejandra Gonzalez-Beltran https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891&atid=886178""" ; obo:IAO_0000117 "Person: Alejandra Gonzalez-Beltran", "Person: Philippe Rocca-Serra" ; obo:IAO_0000119 "ISA tools project (http://isa-tools.org)" ; a owl:AnnotationProperty ; rdfs:label "ISA alternative term"@en . obo:OBI_0001930 obo:IAO_0000111 "categorical value specification" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "A value specification that is specifies one category out of a fixed number of nominal categories" ; obo:IAO_0000117 "PERSON:Bjoern Peters" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "categorical value specification" ; rdfs:subClassOf obo:OBI_0001933 . obo:OBI_0001933 obo:IAO_0000111 "value specification" ; obo:IAO_0000112 "The value of 'positive' in a classification scheme of \"positive or negative\"; the value of '20g' on the quantitative scale of mass." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An information content entity that specifies a value within a classification scheme or on a quantitative scale." ; obo:IAO_0000116 "This term is currently a descendant of 'information content entity', which requires that it 'is about' something. A value specification of '20g' for a measurement data item of the mass of a particular mouse 'is about' the mass of that mouse. However there are cases where a value specification is not clearly about any particular. In the future we may change 'value specification' to remove the 'is about' requirement." ; obo:IAO_0000117 "PERSON:Bjoern Peters" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "value specification" ; rdfs:subClassOf obo:IAO_0000030 . obo:OBI_0001938 obo:IAO_0000111 "has value specification" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A relation between an information content entity and a value specification that specifies its value." ; obo:IAO_0000117 "PERSON: James A. Overton" ; obo:IAO_0000119 "OBI" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has value specification" ; rdfs:subPropertyOf obo:BFO_0000051 . obo:OBI_0003456 obo:IAO_0000111 "in vivo challenge" ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "The administration of a challenge to a live host." ; obo:IAO_0000117 "Hector Guzman-Orozco" ; obo:IAO_0000119 "IEDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "in vivo challenge" ; rdfs:subClassOf obo:OBI_0600007 . obo:OBI_0100026 obo:IAO_0000111 "organism"@en ; obo:IAO_0000112 "animal"@en, "fungus"@en, "plant"@en, "virus"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs."@en ; obo:IAO_0000116 "10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')", """13-02-2009: OBI doesn't take position as to when an organism starts or ends being an organism - e.g. sperm, foetus. This issue is outside the scope of OBI.""" ; obo:IAO_0000117 "GROUP: OBI Biomaterial Branch" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Organism"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "organism"@en ; rdfs:subClassOf obo:BFO_0000040 ; owl:equivalentClass [ a owl:Class ; owl:unionOf (obo:NCBITaxon_10239 obo:NCBITaxon_2 obo:NCBITaxon_2157 obo:NCBITaxon_2759 ) ] . obo:OBI_0100046 obo:IAO_0000111 "phosphate buffered saline solution"@en ; obo:IAO_0000112 "PMID: 16279733.Dent Mater J. 2005 Sep;24(3):414-21.PBS buffer solutions with different pH values can change porosity of DNA-chitosan complexes."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "Phosphate buffered saline (abbreviated PBS) is a buffer solution commonly used in biochemistry. It is a salty solution containing sodium chloride, sodium phosphate and in some preparations potassium chloride and potassium phosphate. The buffer helps to maintain a constant pH. The concentration usually matches the human body (isotonic)."@en ; obo:IAO_0000117 "PERSON: Melanie Courtot"@en, "PERSON: Philippe Rocca-Serra", "PERSON: Tina Boussard"@en ; obo:IAO_0000118 "PBS buffer"@en ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Phosphate_buffered_saline"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "phosphate buffered saline solution"@en ; rdfs:subClassOf obo:OBI_0302729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000576 [ a owl:Restriction ; owl:allValuesFrom obo:CHEBI_26710 ; owl:onProperty obo:OBI_0000643 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000576 [ a owl:Restriction ; owl:allValuesFrom obo:CHEBI_37586 ; owl:onProperty obo:OBI_0000643 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0302731 ] . obo:OBI_0200000 obo:IAO_0000111 "data transformation"@en ; obo:IAO_0000112 "The application of a clustering protocol to microarray data or the application of a statistical testing method on a primary data set to determine a p-value." ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A planned process that produces output data from input data."@en ; obo:IAO_0000117 "Elisabetta Manduchi"@en, "Helen Parkinson"@en, "James Malone"@en, "Melanie Courtot"@en, "Philippe Rocca-Serra", "Richard Scheuermann"@en, "Ryan Brinkman"@en, "Tina Hernandez-Boussard"@en ; obo:IAO_0000118 "data analysis"@en, "data processing"@en ; obo:IAO_0000119 "Branch editors"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "data transformation"@en ; rdfs:subClassOf obo:OBI_0000011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Restriction ; owl:onProperty obo:RO_0000059 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:IAO_0000064 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:IAO_0000005 ] ) ] ] ], [ a owl:Restriction ; owl:allValuesFrom obo:IAO_0000027 ; owl:onProperty obo:OBI_0000293 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0200166 ] . obo:OBI_0200166 obo:IAO_0000111 "data transformation objective"@en ; obo:IAO_0000112 "normalize objective"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An objective specification to transformation input data into output data"@en ; obo:IAO_0000116 "Modified definition in 2013 Philly OBI workshop" ; obo:IAO_0000117 "James Malone"@en ; obo:IAO_0000119 "PERSON: James Malone"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "data transformation objective"@en ; rdfs:subClassOf obo:IAO_0000005 . obo:OBI_0200201 obo:IAO_0000111 "ANOVA" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "A statistical hypothesis test in which the means of several groups are all equal." ; obo:IAO_0000117 "James Malone" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "ANOVA" ; rdfs:subClassOf obo:OBI_0000673 . obo:OBI_0302729 obo:IAO_0000111 "chemical solution"@en ; obo:IAO_0000112 "PMID: 18289311.Anesth Analg. 2008 Apr;106(4):1078-86.Less impairment of hemostasis and reduced blood loss in pigs after resuscitation from hemorrhagic shock using the small-volume concept with hypertonic saline/hydroxyethyl starch as compared to administration of 4% gelatin or 6% hydroxyethyl starch solution."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A material entity that is made up of at least 2 scattered molecular aggregates, one playing the role of solvent and the other one playing the role of solute."@en ; obo:IAO_0000117 "PERSON: Bjoern Peters", "PERSON: Philippe Rocca-Serra" ; obo:IAO_0000118 "liquid chemical solution"@en ; obo:IAO_0000119 "GROUP: OBI Biomaterial Branch" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "chemical solution"@en ; rdfs:subClassOf obo:BFO_0000040 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf ([ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000576 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0302732 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000576 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0302733 ] ) ] ] ) ] . obo:OBI_0302731 obo:IAO_0000111 "buffer role" ; obo:IAO_0000112 "A buffer of carbonic acid (H2CO3) and bicarbonate (HCO3-) is present in blood plasma, to maintain a pH between 7.35 and 7.45. http://en.wikipedia.org/wiki/Buffer_solution" ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "a role which inheres in some molecular entity realized during the process of buffering" ; obo:IAO_0000117 "Person:Helen Parkinson", "Person:Philippe Rocca-Serra" ; obo:IAO_0000118 "buffer" ; obo:IAO_0000119 "OBI" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "buffer role"@en ; rdfs:subClassOf obo:BFO_0000023 . obo:OBI_0302732 obo:IAO_0000111 "solvent role" ; obo:IAO_0000112 "PMID: 18373502.Transfusion. 2008 Mar 25. Solvent/detergent treatment of platelet concentrates enhances the release of growth factors."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "solvent role is a role which inheres in a molecular entity capable of ensuring the dissolution of another chemical entity and realized by the process of solvation"@en ; obo:IAO_0000117 "Philippe Rocca-Serra" ; obo:IAO_0000119 "adpated from wikipedia (http://en.wikipedia.org/wiki/Solvatation)" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "solvent role"@en ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_23367 ], [ a owl:Restriction ; owl:allValuesFrom obo:OBI_0000685 ; owl:onProperty obo:BFO_0000054 ] . obo:OBI_0302733 obo:IAO_0000111 "solute role" ; obo:IAO_0000112 "PMID: 18380397.Pharmazie. 2008 Feb;63(2):113-21.Deviations of drug solubility in water-cosolvent mixtures from the Jouyban-Acree model--effect of solute structure."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "solute role is a role played by a chemical entity which is dissolved by another chemical entity (the solvent) when creating a solution"@en ; obo:IAO_0000117 "Philippe Rocca-Serra" ; obo:IAO_0000119 "adapted from wikipedia (http://en.wikipedia.org/wiki/Solute)" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "solute role"@en ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_23367 ], [ a owl:Restriction ; owl:allValuesFrom obo:OBI_0000685 ; owl:onProperty obo:BFO_0000054 ] . obo:OBI_0302893 obo:IAO_0000111 "storage" ; obo:IAO_0000112 "PMID: 18550121.Total Prostate Specific Antigen Stability Confirmed After Long-Term Storage of Serum at -80C. J Urol. 2008 Jun 10."@en ; obo:IAO_0000114 obo:IAO_0000120 ; obo:IAO_0000115 "A planned process with the objective to preserve and protect material entities by placing them in an identified location which may have a controlled environment."@en ; obo:IAO_0000117 "Philippe Rocca-Serra" ; obo:IAO_0000119 "OBI-Branch" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "storage"@en ; rdfs:subClassOf obo:OBI_0000838, [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:BFO_0000040 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000806 ] . obo:OBI_0500000 obo:IAO_0000111 "study design"@en ; obo:IAO_0000112 "a matched pairs study design describes criteria by which subjects are identified as pairs which then undergo the same protocols, and the data generated is analyzed by comparing the differences between the paired subjects, which constitute the results of the executed study design."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution." ; obo:IAO_0000116 "Editor note: there is at least an implicit restriction on the kind of data transformations that can be done based on the measured data available." ; obo:IAO_0000117 "PERSON: Chris Stoeckert" ; obo:IAO_0000118 "experimental design"@en ; obo:IAO_0000232 "rediscussed at length (MC/JF/BP). 12/9/08). The definition was clarified to differentiate it from protocol."@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "study design"@en ; rdfs:subClassOf obo:IAO_0000104, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:OBI_0000272 ] . obo:OBI_0600007 obo:IAO_0000111 "administering substance in vivo"@en ; obo:IAO_0000112 "Balb/c mice received an intracameral or subconjunctival injection of trinitrophenylated spleen cells", "injecting mice with 10 ug morphine intranasally, a patient taking two pills of 1 mg aspirin orally"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A process by which a substance is intentionally given to an organism resulting in exposure of the organism to that substance." ; obo:IAO_0000116 "2009-11-10. Tracker: https://sourceforge.net/tracker/?func=detail&aid=2893050&group_id=177891&atid=886178", "Different routes and means of administration should go as children underneath this"@en, """Update the definition based on the discussion. Details see the tracker: https://sourceforge.net/p/obi/obi-terms/738/""", "needs roles such as perturber and perturbee (children of input role). Perturb is too strong. Host might be the name for one role. Others considered: Doner, Donated, Acceptor."@en ; obo:IAO_0000117 "Bjoern Peters"@en, "Person:Bjoern Peters" ; obo:IAO_0000119 "IEDB"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "administering substance in vivo"@en ; rdfs:subClassOf obo:OBI_0000011 . obo:OBI_1110034 obo:IAO_0000111 "antigen" ; obo:IAO_0000114 obo:IAO_0000123 ; obo:IAO_0000115 "A material entity that has the antigen role."@en ; obo:IAO_0000117 "IEDB"@en ; obo:IAO_0000119 "IEDB"@en ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "antigen"@en ; rdfs:subClassOf obo:BFO_0000040 ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000237 ] . obo:OBI_9991118 obo:IAO_0000111 "IEDB alternative term" ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "An alternative term used by the IEDB." ; obo:IAO_0000117 "PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters" ; obo:IAO_0000119 "IEDB" ; a owl:AnnotationProperty ; rdfs:label "IEDB alternative term" . obo:OGG_0000000002 obo:IAO_0000115 "A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. " ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/books/NBK21640/" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "gene"@en ; rdfs:subClassOf obo:BFO_0000040 . obo:OGG_0000000006 obo:IAO_0000115 "A GeneID in the NCBI Gene database " ; obo:IAO_0000117 "Oliver He, Yue Liu" ; a owl:AnnotationProperty ; rdfs:label "NCBI GeneID"@en . obo:OGG_0000000007 obo:IAO_0000115 "the NCBI LocusTag name of a gene " ; obo:IAO_0000117 "Oliver He, Yue Liu" ; a owl:AnnotationProperty ; rdfs:label "NCBI LocusTag"@en . obo:OGG_0000000009 obo:IAO_0000115 "a date of content modification" ; obo:IAO_0000117 "Oliver He, Yue Liu" ; a owl:AnnotationProperty ; rdfs:label "modification date"@en . obo:OGG_0000000015 obo:IAO_0000115 "The NCBITaxon ontology ID of an organism." ; obo:IAO_0000117 "Oliver He, Yue Liu" ; a owl:AnnotationProperty ; rdfs:label "organism NCBITaxon ID"@en . obo:OGG_0000000017 obo:IAO_0000115 "A chromosome ID where a gene is located." ; obo:IAO_0000117 "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "chromosome ID of gene"@en . obo:OGG_0000000018 obo:IAO_0000115 "an annotation property that specifies the type of a gene" ; obo:IAO_0000117 "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "type of gene"@en . obo:OGG_0000000019 obo:IAO_0000115 "an annotation property that specifies a nomenclature status" ; obo:IAO_0000117 "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "nomenclature status"@en . obo:OGG_0000000030 obo:IAO_0000115 "An annotation property that represents a gene's association with PubMed publication(s). " ; obo:IAO_0000117 "Yongqun He" ; a owl:AnnotationProperty ; rdfs:label "has PubMed association"@en . obo:OGG_2000000002 obo:IAO_0000115 "A gene of an organism of Bacteria" ; obo:IAO_0000117 "Yue Liu, Bin Zhao, Oliver He" ; obo:IAO_0000412 ; obo:OGG_0000000015 "2" ; a owl:Class ; rdfs:label "gene of Bacteria" ; rdfs:subClassOf obo:OGG_0000000002 . obo:OGG_2000001224 obo:IAO_0000115 "A gene of an organism of Proteobacteria" ; obo:IAO_0000117 "Yue Liu, Bin Zhao, Oliver He" ; obo:IAO_0000412 ; obo:OGG_0000000015 "1224" ; a owl:Class ; rdfs:label "gene of Proteobacteria" ; rdfs:subClassOf obo:OGG_2000000002 . obo:OGG_2000083332 obo:IAO_0000115 "A gene of an organism of Mycobacterium tuberculosis H37Rv" ; obo:IAO_0000117 "Yue Liu, Bin Zhao, Oliver He" ; obo:IAO_0000412 ; obo:OGG_0000000015 "83332" ; a owl:Class ; rdfs:label "gene of Mycobacterium tuberculosis H37Rv" ; rdfs:subClassOf obo:OGG_2000000002 . obo:OGG_2000224914 obo:IAO_0000115 "A gene of an organism of Brucella melitensis bv. 1 str. 16M" ; obo:IAO_0000117 "Yue Liu, Bin Zhao, Oliver He" ; obo:IAO_0000412 ; obo:OGG_0000000015 "224914" ; a owl:Class ; rdfs:label "gene of Brucella melitensis bv. 1 str. 16M" ; rdfs:subClassOf obo:OGG_2000001224 . obo:OGG_2060083332 obo:IAO_0000115 "A gene of Mycobacterium tuberculosis H37Rv that has a protein-coding gene disposition" ; obo:IAO_0000117 "Bin Zhao, Oliver He" ; obo:IAO_0000412 ; obo:OGG_0000000015 "83332" ; a owl:Class ; rdfs:label "protein-coding gene of Mycobacterium tuberculosis H37Rv" ; rdfs:subClassOf obo:OGG_2000083332 . obo:OGG_2060224914 obo:IAO_0000115 "A gene of Brucella melitensis bv. 1 str. 16M that has a protein-coding gene disposition" ; obo:IAO_0000117 "Bin Zhao, Oliver He" ; obo:IAO_0000412 ; obo:OGG_0000000015 "224914" ; a owl:Class ; rdfs:label "protein-coding gene of Brucella melitensis bv. 1 str. 16M" ; rdfs:subClassOf obo:OGG_2000224914 . obo:OGG_3000885459 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "885459" ; obo:OGG_0000000007 "Rv3602c" ; obo:OGG_0000000009 "20140405" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 20980199" ; dc:description "Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme)" ; a owl:Class ; rdfs:label "panC" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000885594 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "885594" ; obo:OGG_0000000007 "Rv1821" ; obo:OGG_0000000009 "20140329" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 17030572; 18487341; 19240020; 20980199; 24297168" ; dc:description "Possible preprotein translocase ATPase SecA2" ; a owl:Class ; rdfs:label "secA2" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000885596 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "885596" ; obo:OGG_0000000007 "Rv3601c" ; obo:OGG_0000000009 "20140405" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 20980199" ; dc:description "Probable aspartate 1-decarboxylase precursor PanD (aspartate alpha-decarboxylase)" ; a owl:Class ; rdfs:label "panD" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000886960 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "886960" ; obo:OGG_0000000007 "Rv1293" ; obo:OGG_0000000009 "20140405" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 16511157; 19543810; 20980199" ; dc:description "Diaminopimelate decarboxylase LysA (DAP decarboxylase)" ; a owl:Class ; rdfs:label "lysA" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000887603 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "887603" ; obo:OGG_0000000007 "Rv2930" ; obo:OGG_0000000009 "20140322" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 15749014; 20553505; 20980199" ; dc:description "Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)" ; a owl:Class ; rdfs:label "fadD26" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000887681 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "887681" ; obo:OGG_0000000007 "Rv2192c" ; obo:OGG_0000000009 "20140405" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 16337227; 20980199; 23363292" ; dc:description "Probable anthranilate phosphoribosyltransferase TrpD" ; a owl:Class ; rdfs:label "trpD" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000888225 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "888225" ; obo:OGG_0000000007 "Rv2987c" ; obo:OGG_0000000009 "20140405" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 19194004; 20980199" ; dc:description "Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)" ; a owl:Class ; rdfs:label "leuD" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000888491 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "888491" ; obo:OGG_0000000007 "Rv2938" ; obo:OGG_0000000009 "20140322" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 20980199" ; dc:description "Probable daunorubicin-dim-transport integral membrane protein ABC transporter DrrC" ; a owl:Class ; rdfs:label "drrC" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000888751 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "888751" ; obo:OGG_0000000007 "Rv1221" ; obo:OGG_0000000009 "20140406" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 16513743; 18192397; 18606740; 18657035; 20980199" ; dc:description "Alternative RNA polymerase sigma factor SigE" ; a owl:Class ; rdfs:label "sigE" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3000888772 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "888772" ; obo:OGG_0000000007 "Rv0757" ; obo:OGG_0000000009 "20140322" ; obo:OGG_0000000015 "83332" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 9634230; 12368430; 16573683; 18052041; 18065542; 18065544; 18282096; 18757548; 18946503; 19820095; 20363229; 20814030; 20980199; 21634789; 22072719; 22880126" ; dc:description "Possible two component system response transcriptional positive regulator PhoP" ; a owl:Class ; rdfs:label "phoP" ; rdfs:subClassOf obo:OGG_2060083332 . obo:OGG_3001197075 obo:IAO_0000117 "Bin Zhao, Yue Liu, Oliver He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/gene" ; obo:IAO_0000412 ; obo:OGG_0000000006 "1197075" ; obo:OGG_0000000007 "BMEI1364" ; obo:OGG_0000000009 "20140222" ; obo:OGG_0000000015 "224914" ; obo:OGG_0000000017 "I" ; obo:OGG_0000000018 "protein-coding" ; obo:OGG_0000000019 "NCBI-supplied" ; obo:OGG_0000000030 "PMID: 11756688; 12271122; 23161025" ; dc:description "transcriptional regulatory protein MUCR" ; a owl:Class ; rdfs:label "BMEI1364" ; rdfs:subClassOf obo:OGG_2060224914 . obo:OGMS_0000060 obo:IAO_0000117 "Albert Goldfain" ; obo:IAO_0000232 "creation date: 2009-06-23T11:53:49Z" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "bodily process" ; rdfs:subClassOf obo:BFO_0000015 . obo:OGMS_0000061 obo:IAO_0000115 "A bodily process that is clinically abnormal."@en ; obo:IAO_0000117 "Albert Goldfain" ; obo:IAO_0000119 "http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf" ; obo:IAO_0000232 "creation date: 2009-06-23T11:54:29Z" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "pathological bodily process" ; rdfs:subClassOf obo:OGMS_0000060 . obo:OGMS_0000063 obo:IAO_0000115 "The totality of all processes through which a given disease instance is realized."@en ; obo:IAO_0000117 "Albert Goldfain" ; obo:IAO_0000119 "http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf" ; obo:IAO_0000232 "creation date: 2009-06-23T11:55:44Z" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "disease course" ; rdfs:subClassOf obo:BFO_0000015 . obo:OMO_0001000 obo:IAO_0000115 "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en ; obo:IAO_0000116 "This obsolesence reason should be used conservatively. Typical valid examples are: un-necessary grouping classes in disease ontologies, a phenotype term added on the assumption it was a disease."@en ; obo:IAO_0000117 ; obo:IAO_0000233 "https://github.com/information-artifact-ontology/ontology-metadata/issues/77" ; obo:IAO_0000234 "https://orcid.org/0000-0001-5208-3432" ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "out of scope" . obo:OMO_0001001 obo:IAO_0000115 "This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL." ; obo:IAO_0000119 "OBO Operations call" ; oboInOwl:created_by ; a owl:AnnotationProperty ; rdfs:label "logical characteristic of object property" . obo:OMO_0001002 obo:IAO_0000115 "The term was added to the ontology on the assumption it was a valid domain entity, but it turns out the entity does not exist in reality."@en ; obo:IAO_0000116 "This obsolesence reason should be used conservatively. For example: Obsoleting class that describes a breed of cow based on a record in an existing database, that was later retracted as faulty (breed does not exist). Do not use this term to obsolete a historic concept (that was once valid, but not anymore). "@en ; obo:IAO_0000117 ; obo:IAO_0000233 "https://github.com/information-artifact-ontology/ontology-metadata/issues/136" ; obo:IAO_0000234 "https://orcid.org/0000-0002-4142-7153" ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "domain entity does not exist" . obo:OMO_0002000 obo:IAO_0000112 """'part disjoint with' 'defined by construct' \"\"\" PREFIX owl: PREFIX : ; dc:contributor , ; a owl:AnnotationProperty ; rdfs:label "defined by construct" . obo:OMO_0003000 obo:IAO_0000112 "CHEBI:26523 (reactive oxygen species) has an exact synonym (ROS), which is of type OMO:0003000 (abbreviation)" ; obo:IAO_0000115 "A synonym type for describing abbreviations or initalisms" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-03-03"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "abbreviation" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003001 obo:IAO_0000115 "A synonym type for describing ambiguous synonyms" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-03-03"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "ambiguous synonym" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003002 obo:IAO_0000115 "A synonym type for describing dubious synonyms" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-03-03"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "dubious synonym" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003003 obo:IAO_0000112 "EFO:0006346 (severe cutaneous adverse reaction) has an exact synonym (scar), which is of the type OMO:0003003 (layperson synonym)" ; obo:IAO_0000115 "A synonym type for describing layperson or colloquial synonyms" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-03-03"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "layperson synonym" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003004 obo:IAO_0000112 "CHEBI:23367 (molecular entity) has an exact synonym (molecular entities), which is of the type OMO:0003004 (plural form)" ; obo:IAO_0000115 "A synonym type for describing pluralization synonyms" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-03-03"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "plural form" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003005 obo:IAO_0000112 "CHEBI:16189 (sulfate) has an exact synonym (sulphate), which is of the type OMO:0003005 (UK spelling synonym)" ; obo:IAO_0000115 "A synonym type for describing UK spelling variants" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-03-03"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "UK spelling synonym" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003006 obo:IAO_0000115 "A synonym type for common misspellings" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-03-03"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "misspelling" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003007 obo:IAO_0000115 "A synonym type for misnomers, i.e., a synonym that is not technically correct but is commonly used anyway" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-03-03"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "misnomer" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003008 obo:IAO_0000112 "MAPT, the gene that encodes the Tau protein, has a previous name DDPAC. Note: in this case, the name type is more specifically the gene symbol." ; obo:IAO_0000115 "A synonym type for names that have been used as primary labels in the past." ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-07-25"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "previous name" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003009 obo:IAO_0000112 "The legal name for Harvard University (https://ror.org/03vek6s52) is President and Fellows of Harvard College" ; obo:IAO_0000115 "A synonym type for the legal entity name" ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-07-27"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "legal name" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003010 obo:IAO_0000112 "CHEBI:46195 has been assigned the english International Nonproproprietary Name (INN) \"paracetamol\". In some cases such as this one, the INN might be the same as the ontology's primary label" ; obo:IAO_0000115 "The International Nonproprietary Name (INN) is a standardize name for a pharmaceutical drug or active ingredient issued by the World Health Organization (WHO) meant to address the issues with country- or language-specific brand names. These are issued in several languages, including English, Latin, French, Russian, Spanish, Arabic, and Chinese." ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-09-30"^^xsd:date ; oboInOwl:hasExactSynonym "INN" ; a owl:AnnotationProperty ; rdfs:label "International Nonproprietary Name" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003011 obo:IAO_0000112 "nasopharynx (UBERON:0001728) has the latin name \"pars nasalis pharyngis" ; obo:IAO_0000115 "A synonym type for describing Latin term synonyms." ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-10-12"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "latin term" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OMO_0003012 obo:IAO_0000112 "NASA is an word acronym for the US National Aeronautics and Space Administration because the acronym is pronounced. FBI is an initialism (also known as alphabetism) for the US Federal Bureau of Investigation since the letters are pronounced one at a time. JPEG is an acronym for Joint Photographic Experts Group but does not count as a word acronym nor an initialism since it is mixed how it is pronounced." ; obo:IAO_0000115 "A synonym type for describing abbreviations that are a part of the full name's words, such as initialisms or alphabetisms." ; obo:IAO_0000233 ; terms:contributor ; terms:created "2023-11-01"^^xsd:date ; a owl:AnnotationProperty ; rdfs:label "acronym" ; rdfs:subPropertyOf oboInOwl:SynonymTypeProperty . obo:OPL_0000004 obo:IAO_0000115 "A hindgut that is a part of or originated from a Triatominae bug." ; obo:IAO_0000117 "Priti Parikh" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Triatominae hindgut" ; rdfs:subClassOf obo:UBERON_0001046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0001046 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_70999 ] ) ] . obo:OPL_0000007 obo:IAO_0000115 "An exflagellated microgametocyte stage in the lifecycle of Plasmodium falciparum that occurs in the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum exflagellated microgametocyte stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum exflagellated microgametocyte stage" ; rdfs:subClassOf obo:OPL_0000010, obo:OPL_0000119, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000119 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000010 obo:IAO_0000115 "A microgametocyte stage in the Plasmodium falciparum lifecycle that occurs either in the bloodstream of a human host or the midgut of a mosquito vector." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "P. Parkh", "S. Khan." ; obo:IAO_0000118 "P. falciparum microgametocyte stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum microgametocyte stage" ; rdfs:subClassOf obo:OPL_0000192, obo:OPL_0000291, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000143 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000026 obo:IAO_0000115 "A gamete stage in apicomplexan parasites when exflagellated microgametocyte divides into microgamete." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Matt Berriman" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "microgamete stage" ; rdfs:subClassOf obo:OPL_0000181, obo:OPL_0000260, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] . obo:OPL_0000028 obo:IAO_0000115 "A gametocyte stage where a cell differentiates into a female sexual form called macrogametocyte." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "macrogametocyte stage" ; rdfs:subClassOf obo:OPL_0000150 . obo:OPL_0000032 obo:IAO_0000115 "A midgut that is a part of or originated from an Anopheles mosquito." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Anopheles midgut" ; rdfs:subClassOf obo:UBERON_0001045 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0001045 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_7164 ] ) ] . obo:OPL_0000033 obo:IAO_0000115 "A parasite lifecycle stage of trypanosomes. In trypomastigote stage, the kinetoplast is near the posterior end of the body, and the flagellum lies attached to the cell body for most of its length by an undulating membrane." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "Wikipedia: Trypanosomatid" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "trypomastigote stage" ; rdfs:subClassOf obo:OPL_0000181, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5690 ] . obo:OPL_0000035 obo:IAO_0000115 "An erythrocytic schizont stage in the Plasmodium falciparum lifecycle that occurs in the infected erythrocytes of a human host." ; obo:IAO_0000116 "updated according to OPL terms Plasmodium final excel file from C. Janse, S. Khan" ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum erythorcytic schizont stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum erythrocytic schizont stage" ; rdfs:subClassOf obo:OPL_0000158, obo:OPL_0000298, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000078 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000036 obo:IAO_0000115 "A parasite lifecycle stage of apicomplexan species where a daughter cell, called merozoite is produced from schizont through schizogony." ; obo:IAO_0000116 "adjusted to be more general" ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarM.htm" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "merozoite stage" ; rdfs:subClassOf obo:OPL_0000181, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] . obo:OPL_0000040 obo:IAO_0000115 "A hepatocyte that is a part of or originated from a human (Homo sapiens)." ; obo:IAO_0000117 "Priti Parikh" ; obo:IAO_0000118 "human hepatocyte" ; obo:IAO_0000412 ; oboInOwl:hasDbXref "FMA:14515" ; a owl:Class ; rdfs:label "Homo sapiens hepatocyte" ; rdfs:subClassOf obo:OPL_0000312 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000182 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_9606 ] ) ] . obo:OPL_0000042 obo:IAO_0000115 "An erythrocytic ring trophozoite stage in the Plasmodium falciparum life cycle that occurs in erythrocytes of a human host. During this stage some Plasmodium falciparum merozoites undergo asexual reproduction cycle in erythrocytes and form young trophozoites that are referred to as \"ring form\" due to their morphology." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum erythrocytic ring trophozoite stage" ; obo:IAO_0000119 "Wikipedia: Plasmodium falciparum biology" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum erythrocytic ring trophozoite stage" ; rdfs:subClassOf obo:OPL_0000207, obo:OPL_0000305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000048 obo:IAO_0000115 "A lifecycle stage of Trypanosoma brucei." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "T. brucei lifecycle stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Trypanosoma brucei lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5691 ] ) ] . obo:OPL_0000050 obo:IAO_0000115 "A Plasmodium falciparum gametocyte that is a male gametocyte and found in either bloodstream of a human host or midgut of a mosquito vector. The microgametocyte is a precursor cell of the microgamete." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum microgametocyte" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum microgametocyte" ; rdfs:subClassOf obo:OPL_0000249, obo:OPL_0000269, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000010 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000057 obo:IAO_0000115 "A parasite lifecycle stage of some protozoan parasites that is a non-reproductive, feeding and growing stage." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarT.htm" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "trophozoite stage" ; rdfs:subClassOf obo:OPL_0000181, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] . obo:OPL_0000059 obo:IAO_0000115 "A schizont stage that occurs in hepatocyte where sporozoites mature into a schizont." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Matt Berriman", "Priti Parikh" ; obo:IAO_0000119 "PMID:11006474" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "hepatic schizont stage" ; rdfs:subClassOf obo:OPL_0000084 . obo:OPL_0000060 obo:IAO_0000115 "A Plasmodium falciparum divides through schizogony. Depending on its location, it is either called hepatic or erythrocytic schizont. The schizont is a dividing stage with 2 or more nuclei." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum schizont" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum schizont" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000275, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000158 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000068 obo:IAO_0000115 "A macrogametocyte stage in the Plasmodium falciparum lifecycle that occurs either in the bloodstream of a human host or the midgut of a mosquito vector." ; obo:IAO_0000116 "gametocytes are mainly found in the blood" ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parikh", "S. Khan" ; obo:IAO_0000118 "P. falciparum macrogametocyte stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum macrogametocyte stage" ; rdfs:subClassOf obo:OPL_0000192, obo:OPL_0000290, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000028 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000073 obo:IAO_0000115 "A parasite lifecycle stage of sporozoa consisting of a zygote enclosed by cyst wall." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "Mosby's Medical Dictionary, 8th edition. � 2009, Elsevier. (http://medical-dictionary.thefreedictionary.com/oocyst)" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "oocyst stage" ; rdfs:subClassOf obo:OPL_0000181, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] . obo:OPL_0000075 obo:IAO_0000115 "A macrogamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum macrogamete stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum macrogamete stage" ; rdfs:subClassOf obo:OPL_0000262, obo:OPL_0000287, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000085 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000078 obo:IAO_0000115 "A schizont stage that occurs in erythrocytes where trophozoites mature into a schizont and schizont produces daughter trophozoites or merozoites." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Matt Berriman", "Priti Parikh" ; obo:IAO_0000119 "PMID: 11006474" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "erythrocytic schizont stage" ; rdfs:subClassOf obo:OPL_0000084 . obo:OPL_0000084 obo:IAO_0000115 "A parasite lifecycle stage that is the multinucleate stage in the development of some members of the Sarcodina and some sporozoans during schizogony." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "http://medical-dictionary.thefreedictionary.com/schizont" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "schizont stage" ; rdfs:subClassOf obo:OPL_0000181, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] . obo:OPL_0000085 obo:IAO_0000115 "A gamete stage in parasites when macrogametocytes produce macrogametes through the process known as gametogenesis." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "http://www.tulane.edu/~wiser/malaria/mal_lc.PDF" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "macrogamete stage" ; rdfs:subClassOf obo:OPL_0000181, obo:OPL_0000260, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] . obo:OPL_0000089 obo:IAO_0000115 "A Plasmodium falciparum that is a 'banana-shaped' form and originates from the round zygote. The ookinete is found in the midgut of a mosquito vector and traverses the midgut wall of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum ookinete" ; obo:IAO_0000119 "Wikipedia: Plasmodium falciparum biology" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum ookinete" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000274, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] . obo:OPL_0000093 obo:IAO_0000115 "A hepatic schizont stage in the lifecycle of Plasmodium falciparum that occurs in the infected hepatocytes of a human host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum hepatic schizont stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum hepatic schizont stage" ; rdfs:subClassOf obo:OPL_0000158, obo:OPL_0000299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000040 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000059 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000096 obo:IAO_0000115 "An erythrocyte that is a part of or originated from a human (Homo sapiens)." ; obo:IAO_0000117 "Priti Parikh" ; obo:IAO_0000118 "human RBC", "human erythrocyte", "human red blood cell" ; obo:IAO_0000412 ; oboInOwl:hasDbXref "FMA:62845" ; a owl:Class ; rdfs:label "Homo sapiens erythrocyte" ; rdfs:subClassOf obo:OPL_0000414 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000232 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_9606 ] ) ] . obo:OPL_0000103 obo:IAO_0000115 "A merozoite stage in the Plasmodium falciparum lifecycle that occurs in the bloodstream or hepatocytes of a human host." ; obo:IAO_0000117 "Chris Stoeckert", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum merozoite stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum merozoite stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000292, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000036 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000110 obo:IAO_0000115 "A Plasmodium falciparum schizont that is found in infected erythrocytes of a human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum erythrocytic schizont" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum erythrocytic schizont" ; rdfs:subClassOf obo:OPL_0000060, obo:OPL_0000276, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000035 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000113 obo:IAO_0000115 "An oocyst stage in the Plasmodium falciparum lifecycle that occurs on the hemocoel side of the midgut of a mosquito vector. During this stage Plasmodium falciparum ookinete invades and escapes midgut wall of mosquito and embed itself onto the exterior of the gut membrane and develop encysted zygote, called oocyst." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum oocyst stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum oocyst stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000295, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000073 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000115 obo:IAO_0000115 "A sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Matt Berrimen", "Priti Parikh", "S. Khan" ; obo:IAO_0000118 "P. falciparum sporozoite stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum sporozoite stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000300, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000117 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000121 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000152 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000117 obo:IAO_0000115 "Blood that is part of or originated from a human (Homo sapiens)." ; obo:IAO_0000116 "previous def was: blood of human" ; obo:IAO_0000117 "Chris Stoeckert" ; obo:IAO_0000118 "human blood" ; obo:IAO_0000119 "OPL" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Homo sapiens blood" ; rdfs:subClassOf obo:OPL_0000320 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0000178 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_9606 ] ) ] . obo:OPL_0000119 obo:IAO_0000115 "A microgametocyte stage in some apicomplexan parasites where microgametocyte gets matured and form microgamete through the process known as exflagellation." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "exflagellated microgametocyte stage" ; rdfs:subClassOf obo:OPL_0000143 . obo:OPL_0000121 obo:IAO_0000115 "A salivary gland that is a part of or originated from an Anopheles mosquito." ; obo:IAO_0000117 "Priti Parikh" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Anopheles salivary gland" ; rdfs:subClassOf obo:UBERON_0001044 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0001044 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_7164 ] ) ] . obo:OPL_0000130 obo:IAO_0000115 "A Plasmodium falciparum that is produced in a schizont, found in the bloodstream of a human host and invades erythrocytes." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parkh" ; obo:IAO_0000118 "P. falciparum merozoite" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum merozoite" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000270, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000103 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000137 obo:IAO_0000115 "A Plasmodium falciparum is formed in the oocyst. It migrates to and resides in the salivary glands of the mosquito vector. A distinction is made between oocyst-derived and salivary gland-derived sporozoites. Sporozoites invade hepatocytes in the vertebrate host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum sporozoite" ; obo:IAO_0000119 "Wikipedia: Plasmodium falciparum biology" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum sporozoite" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000278, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000115 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000117 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000121 ] . obo:OPL_0000138 obo:IAO_0000115 "A Plasmodium falciparum that oocyst is formed, after traversal of the midgut wall by the ookinete stage, on the hemocoel side of the midgut wall of the mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum oocyst" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum oocyst" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000273, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000113 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] . obo:OPL_0000140 obo:IAO_0000115 "An early trophozoite stage of Plasmodium sp. where a large central vacuole and peripheral nucleus give an appearance of a signet ring." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarR.htm" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "erythrocytic ring trophozoite stage" ; rdfs:subClassOf obo:OPL_0000243 . obo:OPL_0000143 obo:IAO_0000115 "A gametocyte stage where a cell differentiates into a male sexual form called microgametocyte." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "microgametocyte stage" ; rdfs:subClassOf obo:OPL_0000150 . obo:OPL_0000146 obo:IAO_0000115 "A Plasmodium falciparum is a feeding form. The trophozoite stage has only 1 nucleus. Depending on its location, it is either called hepatic or erythrocytic trophozoite." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum trophozoite" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum trophozoite" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000281, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000251 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000150 obo:IAO_0000115 "A life cycle stage where a cell differentiates into male or female sexual forms." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "gametocyte stage" ; rdfs:subClassOf obo:UBERON_0000105 . obo:OPL_0000152 obo:IAO_0000115 "A parasite lifecycle stage of some sporozoans where cells divide through sporogony producing daughter cells called sporozoites that infect new hosts." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarS.htm" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "sporozoite stage" ; rdfs:subClassOf obo:OPL_0000181, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] . obo:OPL_0000153 obo:IAO_0000115 "A parasite lifecycle stage of some sporozoans where motile and elongated zygote is formed by the fertilization of the macrogamete during the sexual reproductive phase of the sporozoan life cycle, specifically the malarial parasite Plasmodium." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "Mosby's Medical Dictionary, 8th edition. � 2009, Elsevier. (http://medical-dictionary.thefreedictionary.com/ookinete)" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "ookinete stage" ; rdfs:subClassOf obo:OPL_0000181, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] . obo:OPL_0000158 obo:IAO_0000115 "A schizont stage in the Plasmodium falciparum lifecycle that occurs in erythrocytes or in hepatocytes." ; obo:IAO_0000116 "updated according to OPL terms Plasmodium final excel file from C. Janse, S. Khan" ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum schizont stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum schizont stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000297, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000084 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000161 obo:IAO_0000115 "A Plasmodium falciparum zygote is formed after fertilisation of the macrogamete by a microgamete in the midgut of the mosquito vector. This round form is the only diploid stage in the Plasmodium falciparum life cycle." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "P. Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum zygote" ; obo:IAO_0000119 "Wikipedia: Plasmodium falciparum biology" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum zygote" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000285, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000199 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] . obo:OPL_0000162 obo:IAO_0000115 "A Plasmodium falciparum microgametocyte that is matured with flagellated motile microgametes still attached to its central body. Exflagellated microgametocyte of Plasmodium falciparum is found in the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Matt Berriman", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum exflagellated microgametocyte" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum exflagellated microgametocyte" ; rdfs:subClassOf obo:OPL_0000050, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000007 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] . obo:OPL_0000164 obo:IAO_0000115 "A Trypanosoma cruzi that is found in the bloodstream of infected mammals. It is a non-dividing form that is infectious for its insect vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "T. cruzi trypomastigote" ; obo:IAO_0000119 "http://dna.kdna.ucla.edu/parasite_course-old/cruzi_files/intro.htm" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Trypanosoma cruzi trypomastigote" ; rdfs:subClassOf obo:NCBITaxon_5693, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000169 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000004 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000320 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000321 ] . obo:OPL_0000165 obo:IAO_0000115 "A lifecycle stage of Plasmodium falciparum." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum lifecycle stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000167 obo:IAO_0000115 "A Plasmodium falciparum gamete that is a matured form of the macrogametocyte and is found in the midgut of a mosquito vector. The macrogamete is fertilized by the microgamete, forming the zygote" ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000118 "P. falciparum macrogamete" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum macrogamete" ; rdfs:subClassOf obo:OPL_0000258, obo:OPL_0000265, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000075 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] . obo:OPL_0000169 obo:IAO_0000115 "A trypomastigote stage in the Trypanosoma cruzi lifecycle that occurs either in the vertebrate host or an insect vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "T. cruzi trypomastigote stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Trypanosoma cruzi trypomastigote stage" ; rdfs:subClassOf obo:OPL_0000033, obo:OPL_0000185, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000004 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000320 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000033 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5693 ] ) ] . obo:OPL_0000170 obo:IAO_0000115 "A microgamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum microgamete stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum microgamete stage" ; rdfs:subClassOf obo:OPL_0000262, obo:OPL_0000288, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000026 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000171 obo:IAO_0000115 "A parasite role which is realized only during parasitic infection of a human." ; obo:IAO_0000116 "previous def was not about a role." ; obo:IAO_0000117 "Chris Stoeckert", "Priti Parikh" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "human parasite role" ; rdfs:subClassOf obo:IDO_0000403 . obo:OPL_0000174 obo:IAO_0000115 "A Plasmodium falciparum gamete that is a matured form of exflagellated microgametocyte and found in the midgut of a mosquito vector. The microgamete fertilizes the macrogamete, forming the zygote." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000118 "P. falciparum microgamete" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum microgamete" ; rdfs:subClassOf obo:OPL_0000258, obo:OPL_0000266, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000170 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] . obo:OPL_0000175 obo:IAO_0000115 "A trypomastigote stage in the Trypanosoma brucei lifecycle that occurs in the vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "T. brucei trypomastigote stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Trypanosoma brucei trypomastigote stage" ; rdfs:subClassOf obo:OPL_0000033, obo:OPL_0000048, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000313 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000320 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000033 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5691 ] ) ] . obo:OPL_0000181 obo:IAO_0000115 "A life cycle stage of a parasite." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "parasite lifecycle stage" ; rdfs:subClassOf obo:UBERON_0000105 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0000105 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000232 ] ) ] . obo:OPL_0000182 obo:IAO_0000115 "A Trypanosoma brucei that is a Trypomastigote form of Trypanosoma brucei. In this form the large kinetoplast is postnuclear and is at the most posterior part of the body and the flagellum emerges from the flagellar pocket, and runs along the entire length of the body as an undulating membrane." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "T. brucei trypomastigote" ; obo:IAO_0000119 "http://dna.kdna.ucla.edu/parasite_course-old/african%20tryps%20new_files/contents1.htm" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Trypanosoma brucei trypomastigote" ; rdfs:subClassOf obo:NCBITaxon_5691, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000175 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000313 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000320 ] . obo:OPL_0000185 obo:IAO_0000115 "A lifecycle stage of Trypanosoma cruzi." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "T. cruzi lifecycle stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Trypanosoma cruzi lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5693 ] ) ] . obo:OPL_0000187 obo:IAO_0000115 "An ookinete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector and on the outside of the midgut." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum ookinete stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum ookinete stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000296, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000153 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000190 obo:IAO_0000115 "A Plasmodium falciparum schizont that is found in infected hepatocytes (i.e., liver cells) of a human host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum hepatic schizont" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum hepatic schizont" ; rdfs:subClassOf obo:OPL_0000060, obo:OPL_0000277, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000093 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000040 ] . obo:OPL_0000192 obo:IAO_0000115 "A gametocyte stage in the lifecycle of Plasmodium falciparum." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum gametocyte stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum gametocyte stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000289, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000150 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000199 obo:IAO_0000115 "A zygote stage in the Plasmodium falciparum lifecycle that occurs in the midgut of the mosquito vector where a microgamete and a macrogamete fertilizes each other to produce a diploid cell." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Priti Parikh" ; obo:IAO_0000118 "P. falciparum zygote stage" ; obo:IAO_0000119 "Wikipedia: Plasmodium falciparum biology" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum zygote stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000307, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0000106 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000206 obo:IAO_0000115 "A Plasmodium falciparum gametocyte that is a female gametocyte and found either in bloodstream of a human host or midgut of mosquito vector. The macrogametocyte is a precursor of the macrogamete." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum macrogametocyte" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum macrogametocyte" ; rdfs:subClassOf obo:OPL_0000249, obo:OPL_0000268, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000207 obo:IAO_0000115 "An erythrocytic trophozoite stage in the Plasmodium falciparum life cycle that occurs in erythrocytes of a human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum erythrocytic trophozoite stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum erythrocytic trophozoite stage" ; rdfs:subClassOf obo:OPL_0000251, obo:OPL_0000304, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000243 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000222 obo:IAO_0000115 "A Plasmodium falciparum erythrocytic trophozoite that is found in erythrocytes. It is a young trophozoite stage that has a typical 'ring-like' appearance. Ring-form trophozoites of Plasmodium falciparum are often thin and delicate, measuring on average 1/5 the diameter of the red blood cell." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "Priti Parkh", "S. Khan" ; obo:IAO_0000118 "P. falciparum erythrocytic ring trophozoite" ; obo:IAO_0000119 "http://www.dpd.cdc.gov/dpdx/html/frames/m-r/malaria/falciparum/body_malariadffalcring.htm" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum erythrocytic ring trophozoite" ; rdfs:subClassOf obo:OPL_0000244, obo:OPL_0000283, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000042 ] . obo:OPL_0000232 obo:IAO_0000115 "An organism living in, with, or on another organism in parasitism. Individual members of parasite species, such as Leishmania, Plasmodium, Trypanosoma, etc. are members of this class." ; obo:IAO_0000117 "Jie Zheng", "Priti Parikh" ; obo:IAO_0000119 "http://www.merriam-webster.com/dictionary/parasite?show=0&t=1310398415" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "parasite organism" ; rdfs:subClassOf obo:OBI_0100026 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:IDO_0000403 ] ) ] . obo:OPL_0000241 obo:IAO_0000115 "A Plasmodium falciparum merozoite that is produced in a hepatic schizont and released into the bloodstream of a human host. These forms invade erythrocytes." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum hepatic merozoite" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum hepatic merozoite" ; rdfs:subClassOf obo:OPL_0000130, obo:OPL_0000272, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000246 ] . obo:OPL_0000242 obo:IAO_0000115 "A Plasmodium falciparum merozoite that is produced in an erythrocytic schizont and released into the bloodstream of a human host. These forms invade erythrocytes." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum erythrocytic merozoite" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum erythrocytic merozoite" ; rdfs:subClassOf obo:OPL_0000130, obo:OPL_0000271, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000245 ] . obo:OPL_0000243 obo:IAO_0000115 "A trophozoite stage in some protozoan parasite life cycle that occurs in erythrocytes." ; obo:IAO_0000116 "definition adapted from that for P. falciparum erythrocytic trophozoite stage and parent trophozoite stage" ; obo:IAO_0000117 "Chris Stoeckert" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "erythrocytic trophozoite stage" ; rdfs:subClassOf obo:OPL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000232 ] . obo:OPL_0000244 obo:IAO_0000115 "A Plasmodium falciparum trophozoite that is found in erythrocytes. It is a feeding stage with a single nucleus." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum erythrocytic trophozoite" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum erythrocytic trophozoite" ; rdfs:subClassOf obo:OPL_0000146, obo:OPL_0000282, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000207 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000245 obo:IAO_0000115 "An erythrocytic merozoite stage in the Plasmodium falciparum lifecycle that occurs in the bloodstream of a human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum erythrocytic merozoite stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum erythrocytic merozoite stage" ; rdfs:subClassOf obo:OPL_0000103, obo:OPL_0000293 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000248 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000246 obo:IAO_0000115 "A hepatic merozoite stage in the Plasmodium falciparum lifecycle that occurs in the hepatocyte of a human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum hepatic merozoite stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum hepatic merozoite stage" ; rdfs:subClassOf obo:OPL_0000103, obo:OPL_0000294 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000247 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000247 obo:IAO_0000115 "A merozoite stage in the Plasmodium lifecycle that occurs in the hepatocyte of a vertebrate host." ; obo:IAO_0000116 "definition adapted from that for P. falciparum hepatic merozoite stage" ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "hepatic merozoite stage" ; rdfs:subClassOf obo:OPL_0000036, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000182 ] . obo:OPL_0000248 obo:IAO_0000115 "A merozoite stage in the apicomplexan lifecycle that occurrs in the bloodstream of a vertebrate host." ; obo:IAO_0000116 "definition adapted from that for P. falciparum salivary erythrocytic merozoite stage and from the general merozoite definition" ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "erythrocytic merozoite stage" ; rdfs:subClassOf obo:OPL_0000036 . obo:OPL_0000249 obo:IAO_0000115 "A Plasmodium falciparum that is located either in the bloodstream of the human host or midgut of mosquito vector. Gametocytes are the precursor cells of the macro- or micro-gametes." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "K. Louis", "S Khan" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum gametocyte" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000267, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000192 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000250 obo:IAO_0000115 "A hepatic trophozoite stage in the Plasmodium falciparum life cycle that occurs in hepatocytes of a human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum hepatic trophozoite stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum hepatic trophozoite stage" ; rdfs:subClassOf obo:OPL_0000251, obo:OPL_0000306, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000040 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000261 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000251 obo:IAO_0000115 "A trophozoite stage in the Plasmodium falciparum lifecycle that occurs in a human host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000118 "P. falciparum trophozoite stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum trophozoite stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000303, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000057 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000252 obo:IAO_0000115 "A sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum oocyst-derived sporozoite stage" ; rdfs:subClassOf obo:OPL_0000115, obo:OPL_0000301 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000256 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000253 obo:IAO_0000115 "A sporozoite stage in the Plasmodium lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the vertebrate host." ; obo:IAO_0000116 "definition adapted from that for P. falciparum salivary gland derived sporozoite stage" ; obo:IAO_0000117 "Chris Stoeckert" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "salivary gland-derived sporozoite stage" ; rdfs:subClassOf obo:OPL_0000152, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001044 ] . obo:OPL_0000254 obo:IAO_0000115 "A salivary gland-derived sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum salivary gland-derived sporozoite stage" ; rdfs:subClassOf obo:OPL_0000115, obo:OPL_0000302 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000253 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000255 obo:IAO_0000115 "A Plasmodium falciparum sporozoite that is formed in the oocyst. It migrates to and resides in the salivary glands of the mosquito vector. Sporozoites invade hepatocytes in a human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum salivary gland-derived sporozoite" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum salivary gland-derived sporozoite" ; rdfs:subClassOf obo:OPL_0000137, obo:OPL_0000280, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000254 ] . obo:OPL_0000256 obo:IAO_0000115 "A sporozoite stage in some parasite lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the vertebrate host." ; obo:IAO_0000116 "definition adapted from that for P. falciparum oocyte derived sporozoite stage" ; obo:IAO_0000117 "Chris Stoeckert" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "oocyst-derived sporozoite stage" ; rdfs:subClassOf obo:OPL_0000152 . obo:OPL_0000257 obo:IAO_0000115 "A Plasmodium falciparum trophozoite that is found in hepatocytes of a human host. It is a feeding stage with a single nucleus" ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum hepatic trophozoite" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum hepatic trophozoite" ; rdfs:subClassOf obo:OPL_0000146, obo:OPL_0000284, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000250 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000040 ] . obo:OPL_0000258 obo:IAO_0000115 "A Plasmodium falciparum that is found in midgut of mosquito vector. There are two forms of gametes: micro- and macrogametocytes." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum gamete" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum gamete" ; rdfs:subClassOf obo:NCBITaxon_5833, obo:OPL_0000264, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000262 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] . obo:OPL_0000259 obo:IAO_0000115 "A Plasmodium falciparum sporozoite that is found in the infected hepatocytes of a human host." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum oocyst-derived sporozoite" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum oocyst-derived sporozoite" ; rdfs:subClassOf obo:OPL_0000137, obo:OPL_0000279, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000252 ] . obo:OPL_0000260 obo:IAO_0000115 "A life cycle stage of some parasites that develop into mature sexual cells." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "gamete stage" ; rdfs:subClassOf obo:UBERON_0000105 . obo:OPL_0000261 obo:IAO_0000115 "A trophozoite stage in some protozoan parasite life cycle that occurs in hepatocytes." ; obo:IAO_0000116 "definition adapted from that for P. falciparum hepatic trophozoite stage and from parent trophozoite stage" ; obo:IAO_0000117 "Chris Stoeckert" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "hepatic trophozoite stage" ; rdfs:subClassOf obo:OPL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000182 ] . obo:OPL_0000262 obo:IAO_0000115 "A gamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector." ; obo:IAO_0000117 "C. Janse", "Chris Stoeckert", "Jie Zheng", "S. Khan" ; obo:IAO_0000118 "P. falciparum gamete stage" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium falciparum gamete stage" ; rdfs:subClassOf obo:OPL_0000165, obo:OPL_0000286, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000260 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ) ] . obo:OPL_0000264 obo:IAO_0000115 "A Plasmodium that is found in the midgut of a mosquito vector during gamete lifecycle stage. There are two forms of gametes: micro- and macrogametocytes." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium gamete" ; rdfs:subClassOf obo:NCBITaxon_5820 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000260 ] ) ] . obo:OPL_0000265 obo:IAO_0000115 "A Plasmodium gamete that is in a matured form of the macrogametocyte and found in the midgut of a mosquito vector. The macrogamete is fertilized by the microgamete, forming the zygote." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium macrogamete" ; rdfs:subClassOf obo:OPL_0000264, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000085 ] ) ] . obo:OPL_0000266 obo:IAO_0000115 "A Plasmodium gamete that is in a matured form of exflagellated microgametocyte and found in the midgut of a mosquito vector. The microgamete fertilises the macrogamete, forming the zygote." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium microgamete" ; rdfs:subClassOf obo:OPL_0000264, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000026 ] ) ] . obo:OPL_0000267 obo:IAO_0000115 "A Plasmodium that is located either in the bloodstream of the vertebrate host or midgut of mosquito vector during gametocyte stage. Gametocytes are the precursor cells of the macro- or microgametes" ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium gametocyte" ; rdfs:subClassOf obo:NCBITaxon_5820 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000150 ] ) ] . obo:OPL_0000268 obo:IAO_0000115 "A Plasmodium gametocyte that is a female gametocyte of Plasmodium and found either in the bloodstream of the vertebrate host or midgut of mosquito vector. The macrogametocyte is a precursor of the macrogamete." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium macrogametocyte" ; rdfs:subClassOf obo:OPL_0000267, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000311 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000028 ] ) ] . obo:OPL_0000269 obo:IAO_0000115 "A Plasmodium gametocyte that is a male gametocyte of Plasmodium and found either in the bloodstream of a vertebrate host or midgut of a mosquito vector. The microgametocyte is a precursor cell of the microgamete" ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium microgametocyte" ; rdfs:subClassOf obo:OPL_0000267, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000311 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000143 ] ) ] . obo:OPL_0000270 obo:IAO_0000115 "A Plasmodium that is during merozoite lifecycle stage, occurs in the bloodstream of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium merozoite" ; rdfs:subClassOf obo:NCBITaxon_5820 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000036 ] ) ] . obo:OPL_0000271 obo:IAO_0000115 "A Plasmodium merozoite that is produced in an erythrocytic schizont and released into the bloodstream of a vertebrate host. These forms invade erythrocytes." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium erythrocytic merozoite" ; rdfs:subClassOf obo:OPL_0000270 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000248 ] ) ] . obo:OPL_0000272 obo:IAO_0000115 "A Plasmodium merozoite that is produced in a hepatic schizont and released into the bloodstream of a vertebrate host. These forms invade erythrocytes." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium hepatic merozoite" ; rdfs:subClassOf obo:OPL_0000270 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000247 ] ) ] . obo:OPL_0000273 obo:IAO_0000115 "A Plasmodium that is formed after traversal of the midgut wall by the ookinete stage, on the hemocoel side of the midgut wall of the mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium oocyst" ; rdfs:subClassOf obo:NCBITaxon_5820, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000073 ] ) ] . obo:OPL_0000274 obo:IAO_0000115 "A Plasmodium that is a 'banana-shaped' form originates from the round zygote. The ookinete is found in the midgut of a mosquito vector and traverses the midgut wall of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium ookinete" ; rdfs:subClassOf obo:NCBITaxon_5820, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000153 ] ) ] . obo:OPL_0000275 obo:IAO_0000115 "A Plasmodium that is a form divides through schizogony. Depending on its location, it is either called hepatic or erythrocytic schizont. The schizont is a dividing stage with 2 or more nuclei." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium schizont" ; rdfs:subClassOf obo:NCBITaxon_5820 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000084 ] ) ] . obo:OPL_0000276 obo:IAO_0000115 "A Plasmodium schizont that is found in infected erythrocytes of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium erythrocytic schizont" ; rdfs:subClassOf obo:OPL_0000275, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000311 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000078 ] ) ] . obo:OPL_0000277 obo:IAO_0000115 "A Plasmodium schizont that is found in infected hepatocytes (i.e. liver cells) of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium hepatic schizont" ; rdfs:subClassOf obo:OPL_0000275, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000059 ] ) ] . obo:OPL_0000278 obo:IAO_0000115 "A Plasmodium that is formed in the oocyst and migrates to and reside in the salivary glands of the mosquito vector. A distinction is made between oocyst-derived and salivary gland-derived sporozoites. Sporozoites invade hepatocytes in the vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium sporozoite" ; rdfs:subClassOf obo:NCBITaxon_5820, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000121 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000310 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000152 ] ) ] . obo:OPL_0000279 obo:IAO_0000115 "A Plasmodium sporozoite that is found in the infected hepatocytes of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium oocyst-derived sporozoite" ; rdfs:subClassOf obo:OPL_0000278 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000256 ] ) ] . obo:OPL_0000280 obo:IAO_0000115 "A Plasmodium sporozoite that is found in the salivary glands of the mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium salivary gland-derived sporozoite" ; rdfs:subClassOf obo:OPL_0000278 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000253 ] ) ] . obo:OPL_0000281 obo:IAO_0000115 "A Plasmodium that is a feeding form which has a single nucleus during the trophozoite stage. Depending on its location, it is either called hepatic or erythrocytic trophozoite." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium trophozoite" ; rdfs:subClassOf obo:NCBITaxon_5820, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000311 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000057 ] ) ] . obo:OPL_0000282 obo:IAO_0000115 "A Plasmodium trophozoite that is found in erythrocytes of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium erythrocytic trophozoite" ; rdfs:subClassOf obo:OPL_0000281, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000311 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000243 ] ) ] . obo:OPL_0000283 obo:IAO_0000115 "A Plasmodium erythrocytic trophozoite that has a typical 'ring-like' appearance. Ring-form trophozoites of Plasmodium are often thin and delicate, measuring on average 1/5 the diameter of the red blood cell." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium erythrocytic ring trophozoite" ; rdfs:subClassOf obo:OPL_0000282 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000140 ] ) ] . obo:OPL_0000284 obo:IAO_0000115 "A Plasmodium trophozoite that is found in hepatocytes." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium hepatic trophozoite" ; rdfs:subClassOf obo:OPL_0000281, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000261 ] ) ] . obo:OPL_0000285 obo:IAO_0000115 "A Plasmodium that is formed after fertilization of the macrogamete by a microgamete in the midgut of the mosquito vector. This round form is the only diploid stage in the Plasmodium life cycle." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Ulrike Boehme" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/2" ; obo:IAO_0000234 "GeneDB" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium zygote" ; rdfs:subClassOf obo:NCBITaxon_5820, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_5820 [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:UBERON_0000106 ] ) ] . obo:OPL_0000286 obo:IAO_0000115 "A gamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium gamete stage" ; rdfs:subClassOf obo:OPL_0000181, obo:OPL_0000260 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000260 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000287 obo:IAO_0000115 "A macrogamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium macrogamete stage" ; rdfs:subClassOf obo:OPL_0000085, obo:OPL_0000286, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000085 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000288 obo:IAO_0000115 "A microgamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium microgamete stage" ; rdfs:subClassOf obo:OPL_0000026, obo:OPL_0000286, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000026 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000289 obo:IAO_0000115 "A gametocyte stage in the lifecycle of Plasmodium." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium gametocyte stage" ; rdfs:subClassOf obo:OPL_0000150, obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000150 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000290 obo:IAO_0000115 "A macrogametocyte stage in the Plasmodium lifecycle that occurs either in the bloodstream of a vertebrate host or the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium macrogametocyte stage" ; rdfs:subClassOf obo:OPL_0000028, obo:OPL_0000289, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000311 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000028 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000291 obo:IAO_0000115 "A microgametocyte stage in the Plasmodium lifecycle that occurs either in the bloodstream of a vertebrate host or the midgut of a mosquito vector." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium microgametocyte stage" ; rdfs:subClassOf obo:OPL_0000143, obo:OPL_0000289, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000311 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000143 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000292 obo:IAO_0000115 "A merozoite stage in the Plasmodium lifecycle that occurs in the bloodstream or hepatocytes of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium merozoite stage" ; rdfs:subClassOf obo:OPL_0000036 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000036 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000293 obo:IAO_0000115 "An erythrocytic merozoite stage in the Plasmodium lifecycle that occurs in the bloodstream of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium erythrocytic merozoite stage" ; rdfs:subClassOf obo:OPL_0000248, obo:OPL_0000292 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000248 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000294 obo:IAO_0000115 "A hepatic merozoite stage in the Plasmodium lifecycle that occurs in the hepatocyte of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium hepatic merozoite stage" ; rdfs:subClassOf obo:OPL_0000247, obo:OPL_0000292 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000247 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000295 obo:IAO_0000115 "An oocyst stage in the Plasmodium lifecycle that occurs on the hemocoel side of the midgut of a mosquito vector. During this stage Plasmodium ookinete invades and escapes midgut wall of mosquito and embed itself onto the exterior of the gut membrane and develop encysted zygote, called oocyst." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium oocyst stage" ; rdfs:subClassOf obo:OPL_0000073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000073 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000296 obo:IAO_0000115 "An ookinete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector and on the outside of the midgut." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium ookinete stage" ; rdfs:subClassOf obo:OPL_0000153, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000153 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000297 obo:IAO_0000115 "A schizont stage in the Plasmodium lifecycle that occurs in erythrocytes or in hepatocytes." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium schizont stage" ; rdfs:subClassOf obo:OPL_0000084 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000084 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000298 obo:IAO_0000115 "An erythrocytic schizont stage in the Plasmodium lifecycle that occurs in the infected erythrocytes of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium erythrocytic schizont stage" ; rdfs:subClassOf obo:OPL_0000078, obo:OPL_0000297, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000311 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000078 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000299 obo:IAO_0000115 "A hepatic schizont stage in the Plasmodium lifecycle that occurs in the infected hepatocytes of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium hepatic schizont stage" ; rdfs:subClassOf obo:OPL_0000059, obo:OPL_0000297, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000059 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000300 obo:IAO_0000115 "A sporozoite stage in the Plasmodium lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium sporozoite stage" ; rdfs:subClassOf obo:OPL_0000152, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000121 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000310 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000152 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000301 obo:IAO_0000115 "A sporozoite stage in the Plasmodium lifecycle that develops in oocyst of the mosquito midgut." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Omar harb" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium oocyst-derived sporozoite stage" ; rdfs:subClassOf obo:OPL_0000256, obo:OPL_0000300 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000256 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000302 obo:IAO_0000115 "A salivary gland-derived sporozoite stage in the Plasmodium lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng", "Omar harb" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium salivary gland-derived sporozoite stage" ; rdfs:subClassOf obo:OPL_0000253, obo:OPL_0000300 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000253 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000303 obo:IAO_0000115 "A trophozoite stage in the Plasmodium lifecycle that occurs in a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium trophozoite stage" ; rdfs:subClassOf obo:OPL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000311 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000057 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000304 obo:IAO_0000115 "An erythrocytic trophozoite stage in the Plasmodium life cycle that occurs in erythrocytes of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium erythrocytic trophozoite stage" ; rdfs:subClassOf obo:OPL_0000243, obo:OPL_0000303, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000311 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000243 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000305 obo:IAO_0000115 "An erythrocytic ring trophozoite stage in the Plasmodium life cycle that occurs in erythrocytes of a vertebrate host. During this stage some Plasmodium merozoites undergo asexual reproduction cycle in erythrocytes and form young trophozoites that are referred to as \"ring form\" due to their morphology." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium erythrocytic ring trophozoite stage" ; rdfs:subClassOf obo:OPL_0000140, obo:OPL_0000304 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000306 obo:IAO_0000115 "A hepatic trophozoite stage in the Plasmodium life cycle that occurs in hepatocytes of a vertebrate host." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium hepatic trophozoite stage" ; rdfs:subClassOf obo:OPL_0000261, obo:OPL_0000303, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000261 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000307 obo:IAO_0000115 "A zygote stage in the Plasmodium lifecycle that occurs in the midgut of the mosquito vector where a microgamete and a macrogamete fertilizes each other to produce a diploid cell." ; obo:IAO_0000117 "Chris Stoeckert", "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium zygote stage" ; rdfs:subClassOf obo:OPL_0000181, obo:UBERON_0000106, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0000106 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ) ] . obo:OPL_0000310 obo:IAO_0000115 "Blood that is part of or originated from a vertebrate." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "OPL" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Vertebrate blood" ; rdfs:subClassOf obo:UBERON_0000178 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0000178 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_7742 ] ) ] . obo:OPL_0000311 obo:IAO_0000115 "An erythrocyte that is a part of or originated from a vertebrate." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "OPL" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Vertebrate erythrocyte" ; rdfs:subClassOf obo:CL_0000232 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000232 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_7742 ] ) ] . obo:OPL_0000312 obo:IAO_0000115 "A hepatocyte that is a part of or originated from a vertebrate." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "OPL" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Vertebrate hepatocyte" ; rdfs:subClassOf obo:CL_0000182 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000182 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_7742 ] ) ] . obo:OPL_0000313 obo:IAO_0000115 "Cerebrospinal fluid that is a part of or originated from a mammal." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Mammalia cerebrospinal fluid" ; rdfs:subClassOf obo:UBERON_0001359 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0001359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_40674 ] ) ] . obo:OPL_0000320 obo:IAO_0000115 "Blood that is part of or originated from a mammalia." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Mammalia blood" ; rdfs:subClassOf obo:OPL_0000310 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:UBERON_0000178 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_40674 ] ) ] . obo:OPL_0000321 obo:IAO_0000115 "A macrophage that is a part of or originated from a mammalia." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Mammalia macrophage" ; rdfs:subClassOf obo:CL_0000235 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000235 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_40674 ] ) ] . obo:OPL_0000325 obo:IAO_0000115 "A parasite lifecycle stage that parasite replicates rapidly within the host cell." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744739/" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "tachyzoite stage" ; rdfs:subClassOf obo:OPL_0000181 . obo:OPL_0000327 obo:IAO_0000115 "A Plasmodium vivax is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium vivax sporozoite" ; rdfs:subClassOf obo:NCBITaxon_5855, obo:OPL_0000278, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000348 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000117 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000121 ] . obo:OPL_0000328 obo:IAO_0000115 "A Plasmodium vivax that is found in the bloodstream of the human host and invades erythrocytes." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium vivax merozoite" ; rdfs:subClassOf obo:NCBITaxon_5855, obo:OPL_0000270, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000349 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000096 ] . obo:OPL_0000330 obo:IAO_0000115 "A Plasmodium berghei is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium berghei sporazoite" ; rdfs:subClassOf obo:NCBITaxon_5821, obo:OPL_0000278, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000351 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000117 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000121 ] . obo:OPL_0000332 obo:IAO_0000115 "A Neospora caninum that is found intracellular in the intermediate hosts in which asexual replication takes place." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890850/" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Neospora caninum tachyzoite" ; rdfs:subClassOf obo:NCBITaxon_29176, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000353 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:NCBITaxon_9611 ] . obo:OPL_0000336 obo:IAO_0000115 "A Sarcocystis neurona that is found in the bloodstream of the human host and invades erythrocytes." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/books/NBK574577/" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Sarcocystis neurona merozoite" ; rdfs:subClassOf obo:NCBITaxon_42890, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000369 ] . obo:OPL_0000338 obo:IAO_0000115 "A Toxoplasma gondii that is formed in tissue in a host and replicates quickly. This replaces the previous term as ." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000118 "Toxoplasma gondii trophozoite" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Toxoplasma gondii tachyzoite" ; rdfs:subClassOf obo:NCBITaxon_5811, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000359 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:NCBITaxon_40674 ] . obo:OPL_0000348 obo:IAO_0000115 "A sporozoite stage in Plasmodium vivax life cycle." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium vivax sporozoite stage" ; rdfs:subClassOf obo:OPL_0000300, obo:OPL_0000374, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000117 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000121 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000152 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5855 ] ) ] . obo:OPL_0000349 obo:IAO_0000115 "A merozoite stage in the Plasmodium vivax life cycle." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium vivax merozoite stage" ; rdfs:subClassOf obo:OPL_0000292, obo:OPL_0000374, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000036 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5855 ] ) ] . obo:OPL_0000351 obo:IAO_0000115 "A sporozoite stage in the Plasmodium berghei life cycle." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium berghei sporazoite stage" ; rdfs:subClassOf obo:OPL_0000300, obo:OPL_0000375, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000040 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000117 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000121 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000152 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5821 ] ) ] . obo:OPL_0000353 obo:IAO_0000115 "A tachyzoite stage in the Neospora caninum life cycle." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890850/" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Neospora caninum tachyzoite stage" ; rdfs:subClassOf obo:OPL_0000325, obo:OPL_0000376, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:NCBITaxon_9611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000325 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_29176 ] ) ] . obo:OPL_0000357 obo:IAO_0000115 "A merozoite stage in the Sarcocystis neurona life cycle." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://wcvm.usask.ca/learnaboutparasites/parasites/sarcocystis-neurona.php" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Sarcocystis neurona merozoite stage" ; rdfs:subClassOf obo:OPL_0000036, obo:OPL_0000379, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000036 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_42890 ] ) ] . obo:OPL_0000359 obo:IAO_0000115 "A tachyzoite stage in the Toxoplasma gondii life cycle." ; obo:IAO_0000116 "Tachyzoites can be found in various organs and tissues during the acute phase of Toxoplasma gondii infection, including lymph nodes, spleen, liver, lungs, and the central nervous system. " ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/21" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Toxoplasma gondii tachyzoite stage" ; rdfs:subClassOf obo:OPL_0000325, obo:OPL_0000380, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:NCBITaxon_40674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000325 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5811 ] ) ] . obo:OPL_0000369 obo:IAO_0000115 "An erythrocyte that is a part of or originated from a Canis lupus familiaris." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Canis lupus familiaris erythrocyte" ; rdfs:subClassOf obo:OPL_0000311 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000232 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_9615 ] ) ] . obo:OPL_0000374 obo:IAO_0000115 "A lifecycle stage of Plasmodium vivax." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium vivax lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5855 ] ) ] . obo:OPL_0000375 obo:IAO_0000115 "A lifecycle stage of Plasmodium berghei." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium berghei lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5821 ] ) ] . obo:OPL_0000376 obo:IAO_0000115 "A lifecycle stage of Neospora caninum." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Neospora caninum lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_29176 ] ) ] . obo:OPL_0000379 obo:IAO_0000115 "A lifecycle stage of Sarcocystis neurona." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Sarcocystis neurona lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_42890 ] ) ] . obo:OPL_0000380 obo:IAO_0000115 "A lifecycle stage of Toxoplasma gondii." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Toxoplasma gondii lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5811 ] ) ] . obo:OPL_0000385 obo:IAO_0000115 "A Plasmodium yoelii in sporozoite stage." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium yoelii sporozoite" ; rdfs:subClassOf obo:NCBITaxon_5861, obo:OPL_0000278, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000400 ] . obo:OPL_0000386 obo:IAO_0000115 "A Plasmodium yoelii in merozoite stage." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium yoelii merozoite" ; rdfs:subClassOf obo:NCBITaxon_5861, obo:OPL_0000270, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000401 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000414 ] . obo:OPL_0000387 obo:IAO_0000115 "A Plasmodium yoelii in gametocyte stage." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium yoelii gametocyte" ; rdfs:subClassOf obo:NCBITaxon_5861, obo:OPL_0000267, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000402 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000414 ] . obo:OPL_0000389 obo:IAO_0000115 "A Plasmodium chabaudi in sporozoite stage." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium chabaudi sporozoite" ; rdfs:subClassOf obo:NCBITaxon_5825, obo:OPL_0000278, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000404 ] . obo:OPL_0000393 obo:IAO_0000115 "A Plasmodium knowlesi in sporozoite stage." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium knowlesi sporozoite" ; rdfs:subClassOf obo:NCBITaxon_5850, obo:OPL_0000278, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000408 ] . obo:OPL_0000394 obo:IAO_0000115 "A Plasmodium knowlesi in merozoite stage." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium knowlesi merozoite" ; rdfs:subClassOf obo:NCBITaxon_5850, obo:OPL_0000270, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:OPL_0000409 ], [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:OPL_0000414 ] . obo:OPL_0000400 obo:IAO_0000115 "A sporozoite stage in the Plasmodium yoelii." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium yoelii sporozoite stage" ; rdfs:subClassOf obo:OPL_0000300, obo:OPL_0000415 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000152 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5861 ] ) ] . obo:OPL_0000401 obo:IAO_0000115 "A merozoite stage in the Plasmodium yoelii." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium yoelii merozoite stage" ; rdfs:subClassOf obo:OPL_0000292, obo:OPL_0000415, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000036 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5861 ] ) ] . obo:OPL_0000402 obo:IAO_0000115 "A gametocyte stage in the Plasmodium yoelii." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium yoelii gametocyte stage" ; rdfs:subClassOf obo:OPL_0000289, obo:OPL_0000415, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000150 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5861 ] ) ] . obo:OPL_0000404 obo:IAO_0000115 "A sporozoite stage in the Plasmodium chabaudi." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium chabaudi sporozoite stage" ; rdfs:subClassOf obo:OPL_0000300, obo:OPL_0000416 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000152 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5825 ] ) ] . obo:OPL_0000408 obo:IAO_0000115 "A sporozoite stage in the Plasmodium knowlesi." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium knowlesi sporozoite stage" ; rdfs:subClassOf obo:OPL_0000300, obo:OPL_0000417 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000152 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5850 ] ) ] . obo:OPL_0000409 obo:IAO_0000115 "A merozoite stage in the Plasmodium knowlesi." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng" ; obo:IAO_0000119 "https://www.cdc.gov/dpdx/malaria/index.html" ; obo:IAO_0000233 "https://github.com/OPL-ontology/OPL/issues/24" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium knowlesi merozoite stage" ; rdfs:subClassOf obo:OPL_0000292, obo:OPL_0000417, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:OPL_0000414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000036 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5850 ] ) ] . obo:OPL_0000414 obo:IAO_0000115 "An erythrocyte that is a part of or originated from a primate." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000118 "primate erythrocyte" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Primates erythrocyte" ; rdfs:subClassOf obo:OPL_0000311 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000232 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:NCBITaxon_9443 ] ) ] . obo:OPL_0000415 obo:IAO_0000115 "A lifecycle stage of Plasmodium yoelii." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium yoelii lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5861 ] ) ] . obo:OPL_0000416 obo:IAO_0000115 "A lifecycle stage of Plasmodium chabaudi." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium chabaudi lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5825 ] ) ] . obo:OPL_0000417 obo:IAO_0000115 "A lifecycle stage of Plasmodium knowlesi." ; obo:IAO_0000117 "Jie Zheng" ; obo:IAO_0000119 "He Group" ; obo:IAO_0000234 "He Group" ; obo:IAO_0000412 ; a owl:Class ; rdfs:label "Plasmodium knowlesi lifecycle stage" ; rdfs:subClassOf obo:OPL_0000181 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OPL_0000181 [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5850 ] ) ] . obo:PATO_0000001 obo:IAO_0000115 "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "PATO:0000072" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000001" ; a owl:Class ; rdfs:label "quality" ; rdfs:subClassOf obo:BFO_0000002 . obo:PATO_0000011 obo:IAO_0000115 "A time quality inhering in a bearer by virtue of how long the bearer has existed." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000011" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "age" ; rdfs:subClassOf obo:PATO_0000165 . obo:PATO_0000044 obo:IAO_0000115 "A physical quality which inheres in a bearer by virtue of the number of the bearer's repetitive actions in a particular time." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000044" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "frequency" ; rdfs:subClassOf obo:PATO_0000001 . obo:PATO_0000047 obo:IAO_0000115 "An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000047" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "biological sex" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0000165 obo:IAO_0000115 "A quality in which events occur in sequence." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000165" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "time" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0000169 obo:IAO_0000115 "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000169" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "viability" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0000719 obo:IAO_0000115 "A viability quality inhering in a bearer or a population by virtue of the bearer's ability to survive or the long term survival ability of a given population." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000719" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "viable" ; rdfs:subClassOf obo:PATO_0000169 . obo:PATO_0000918 obo:IAO_0000115 "A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000918" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "volume" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0001018 obo:IAO_0000115 "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "PATO:0002079" ; oboInOwl:hasDbXref "Wikipedia:Physical_property" ; oboInOwl:hasExactSynonym "relational physical quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001018" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "physical quality" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0001029 obo:IAO_0000115 "A physical quality inhering in a bearer by virtue of ratio of the bearer's output to the bearer's input." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001029" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "efficiency" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0001241 obo:IAO_0000115 "A quality which inheres in a continuant." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "PATO:0001237", "PATO:0001238" ; oboInOwl:hasDbXref "snap:Quality" ; oboInOwl:hasExactSynonym "monadic quality of a continuant", "multiply inhering quality of a physical entity", "quality of a continuant", "quality of a single physical entity", "quality of an object", "quality of continuant" ; oboInOwl:hasNarrowSynonym "monadic quality of an object", "monadic quality of continuant" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001241" ; a owl:Class ; rdfs:comment "Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles." ; rdfs:label "physical object quality" ; rdfs:subClassOf obo:BFO_0000019 . obo:PATO_0001422 obo:IAO_0000115 "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001422" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "dead" ; rdfs:subClassOf obo:PATO_0000169 . obo:PATO_0001677 obo:IAO_0000115 "An efficiency quality inhering in a bearer by virtue of the bearer's lacking efficiency." ; obo:IAO_0000412 ; obo:RO_0002604 obo:PATO_0001678 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001677" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "inefficient" ; rdfs:subClassOf obo:PATO_0001029 . obo:PATO_0001678 obo:IAO_0000115 "An efficiency quality inhering in a bearer by virtue of the bearer's having efficiency." ; obo:IAO_0000412 ; obo:RO_0002604 obo:PATO_0001677 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001678" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "efficient" ; rdfs:subClassOf obo:PATO_0001029 . obo:PATO_0001995 obo:IAO_0000115 "A quality that inheres in an entire organism or part of an organism." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001995" ; a owl:Class ; rdfs:label "organismal quality" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0002146 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the severity of infectious disease caused by the bearer in a target organism." ; obo:IAO_0000412 ; terms:contributor ; oboInOwl:creation_date "2009-10-30T05:04:06Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002146" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "virulence" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0002147 obo:IAO_0000115 "A virulence that is relatively low." ; obo:IAO_0000412 ; obo:RO_0002604 obo:PATO_0002148 ; terms:contributor ; oboInOwl:creation_date "2009-10-30T05:05:02Z" ; oboInOwl:hasExactSynonym "attenuated" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002147" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "reduced virulence" ; rdfs:subClassOf obo:PATO_0002146, obo:PATO_0002303 . obo:PATO_0002303 obo:IAO_0000115 "A quality of an object that has a value that is decreased compared to normal or average." ; obo:IAO_0000412 ; obo:RO_0002604 obo:PATO_0002305 ; terms:contributor ; oboInOwl:creation_date "2011-06-16T06:51:54Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002303" ; a owl:Class ; rdfs:label "decreased object quality" ; rdfs:subClassOf obo:PATO_0000001, obo:PATO_0001241 . obo:PR_000000001 obo:IAO_0000115 "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." ; obo:IAO_0000412 ; oboInOwl:hasExactSynonym "natural protein" ; oboInOwl:hasNarrowSynonym "native protein" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:id "PR:000000001" ; a owl:Class ; rdfs:comment "The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB]." ; rdfs:label "protein" ; rdfs:subClassOf obo:CHEBI_23367 . obo:PR_000001096 obo:IAO_0000115 "A protein that has a core domain composition consisting of a signal peptide, an extracellular domain with multiple Leucine rich repeat (Pfam:PF13855) domain (LRR), a cysteine-rich region, a single-pass transmembrane domain and a C-terminal cytoplasmic tail containing a TIR domain (Pfam:PF01582)." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "PIRSF:PIRSF800008" ; oboInOwl:hasExactSynonym "fam:TLR" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:id "PR:000001096" ; a owl:Class ; rdfs:comment "Category=family." ; rdfs:label "Toll-like receptor" ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000001153 obo:IAO_0000115 "A Toll-like receptor that is a translation product of the human TLR2 gene or a 1:1 ortholog thereof." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "IUPHARobj:1752" ; oboInOwl:hasExactSynonym "CD282", "TLR2", "Toll/interleukin-1 receptor-like protein 4" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:hasRelatedSynonym "TIL4" ; oboInOwl:id "PR:000001153" ; a owl:Class ; rdfs:comment "Category=gene." ; rdfs:label "Toll-like receptor 2" ; rdfs:subClassOf obo:PR_000001096 . obo:PR_000001154 obo:IAO_0000115 "A Toll-like receptor that is a translation product of the human TLR3 gene or a 1:1 ortholog thereof." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "IUPHARobj:1753" ; oboInOwl:hasExactSynonym "CD283", "TLR3" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:id "PR:000001154" ; a owl:Class ; rdfs:comment "Category=gene." ; rdfs:label "Toll-like receptor 3" ; rdfs:subClassOf obo:PR_000001096 . obo:PR_000001155 obo:IAO_0000115 "A Toll-like receptor that is a translation product of the human TLR4 gene or a 1:1 ortholog thereof." ; obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "Toll" ; oboInOwl:hasDbXref "IUPHARobj:1754" ; oboInOwl:hasExactSynonym "CD284", "TLR4" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:hasRelatedSynonym "Lps" ; oboInOwl:id "PR:000001155" ; a owl:Class ; rdfs:comment "Category=gene." ; rdfs:label "Toll-like receptor 4" ; rdfs:subClassOf obo:PR_000001096 . obo:PR_000001158 obo:IAO_0000115 "A Toll-like receptor that is a translation product of the human TLR7 gene or a 1:1 ortholog thereof." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "IUPHARobj:1757" ; oboInOwl:hasExactSynonym "TLR7" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:hasRelatedSynonym "UNQ248/PRO285" ; oboInOwl:id "PR:000001158" ; a owl:Class ; rdfs:comment "Category=gene." ; rdfs:label "Toll-like receptor 7" ; rdfs:subClassOf obo:PR_000001096 . obo:PR_000001159 obo:IAO_0000115 "A Toll-like receptor that is a translation product of the human TLR8 gene or a 1:1 ortholog thereof." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "IUPHARobj:1758" ; oboInOwl:hasExactSynonym "CD288", "TLR8" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:hasRelatedSynonym "UNQ249/PRO286" ; oboInOwl:id "PR:000001159" ; a owl:Class ; rdfs:comment "Category=gene." ; rdfs:label "Toll-like receptor 8" ; rdfs:subClassOf obo:PR_000001096 . obo:PR_000011271 obo:IAO_0000115 "A protein that is a translation product of the human NLRP3 gene or a 1:1 ortholog thereof." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "IUPHARobj:1770" ; oboInOwl:hasExactSynonym "CLR1.1", "NLRP3", "PYRIN-containing APAF1-like protein 1", "angiotensin/vasopressin receptor AII/AVP-like", "caterpiller protein 1.1", "cold autoinflammatory syndrome 1 protein", "cold autoinflammatory syndrome 1 protein homolog", "cryopyrin", "mast cell maturation-associated-inducible protein 1" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:hasRelatedSynonym "C1orf7", "CIAS1", "Mmig1", "NALP3", "PYPAF1" ; oboInOwl:id "PR:000011271" ; a owl:Class ; rdfs:comment "Category=gene." ; rdfs:label "NACHT, LRR and PYD domains-containing protein 3" ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000015399 obo:IAO_0000115 "A SODC domain protein that is a translation product of the human SOD1 gene or a 1:1 ortholog thereof." ; obo:IAO_0000412 ; oboInOwl:hasExactSynonym "SOD1" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:id "PR:000015399" ; a owl:Class ; rdfs:comment "Category=gene." ; rdfs:label "superoxide dismutase [Cu-Zn]" ; rdfs:subClassOf obo:PR_000000001 . obo:PR_000050567 obo:IAO_0000115 "A material entity that minimally consists of a protein." ; obo:IAO_0000412 ; oboInOwl:hasNarrowSynonym "protein", "protein aggregate", "protein complex", "protein-containing complex" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:id "PR:000050567" ; a owl:Class ; rdfs:comment "Note: This includes single proteins and derivatives thereof (PR:000000001), protein-containing complexes (GO:0032991), and protein aggregates (PR:000050566)." ; rdfs:label "protein-containing material entity" ; rdfs:subClassOf obo:BFO_0000040 . obo:PR_P0DTC2 obo:IAO_0000115 "A protein that is a translation product of the S gene in SARS-CoV-2." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "GenPept:YP_009724390", "UniProtKB:P0DTC2" ; oboInOwl:hasExactSynonym "E2 (SARS-CoV-2)", "S (SARS2)", "S glycoprotein (SARS-CoV-2)", "peplomer protein (SARS-CoV-2)", "surface glycoprotein (SARS-CoV-2)" ; oboInOwl:hasOBONamespace "protein" ; oboInOwl:hasRelatedSynonym "2", "GU280_gp02", "S" ; oboInOwl:id "PR:P0DTC2" ; a owl:Class ; rdfs:comment "Category=organism-gene. Note: 1273 aa protein. Undergoes additional processing by proteolytic cleavage." ; rdfs:label "spike glycoprotein (SARS-CoV-2)" ; rdfs:subClassOf obo:PR_000000001 . obo:PR_P0DTC4 obo:IAO_0000115 "Category=organism-gene. Note: 75 aa protein. A protein that is a translation product of the E gene in SARS-CoV-2." ; obo:IAO_0000118 "E (SARS2)", "envelope protein (SARS-CoV-2)", "sM protein (SARS-CoV-2)" ; obo:IAO_0000412 ; oboInOwl:hasDbXref "UniProtKB:P0DTC4" ; a owl:Class ; rdfs:label "envelope small membrane protein (SARS-CoV-2)" ; rdfs:subClassOf obo:VO_0004990 . obo:RO_0000052 obo:IAO_0000111 "inheres in"@en ; obo:IAO_0000112 "this fragility is a characteristic of this vase"@en, "this red color is a characteristic of this apple"@en ; obo:IAO_0000115 "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ; obo:IAO_0000118 "inheres_in"@en ; obo:IAO_0000412 ; obo:RO_0001900 obo:RO_0001901 ; a owl:FunctionalProperty, owl:ObjectProperty ; rdfs:comment "Note that this relation was previously called \"inheres in\", but was changed to be called \"characteristic of\" because BFO2 uses \"inheres in\" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing." ; rdfs:label "characteristic of"@en ; rdfs:subPropertyOf obo:RO_0002314 ; owl:inverseOf obo:RO_0000053 . obo:RO_0000053 obo:IAO_0000111 "bearer of"@en ; obo:IAO_0000112 "this apple is bearer of this red color"@en, "this vase is bearer of this fragility"@en ; obo:IAO_0000115 "Inverse of characteristic_of"@en ; obo:IAO_0000116 "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist."@en ; obo:IAO_0000118 "bearer_of"@en, "is bearer of"@en ; obo:IAO_0000412 ; obo:RO_0001900 obo:RO_0001901 ; a owl:InverseFunctionalProperty, owl:ObjectProperty ; rdfs:label "has characteristic"@en ; rdfs:range obo:BFO_0000020 . obo:RO_0000056 obo:IAO_0000111 "participates in"@en ; obo:IAO_0000112 "this blood clot participates in this blood coagulation"@en, "this input material (or this output material) participates in this process"@en, "this investigator participates in this investigation"@en ; obo:IAO_0000115 "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ; obo:IAO_0000118 "participates_in"@en ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000002 ; rdfs:label "participates in"@en ; rdfs:range obo:BFO_0000003 ; owl:inverseOf obo:RO_0000057 . obo:RO_0000057 obo:IAO_0000111 "has participant"@en ; obo:IAO_0000112 "this blood coagulation has participant this blood clot"@en, "this investigation has participant this investigator"@en, "this process has participant this input material (or this output material)"@en ; obo:IAO_0000115 "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ; obo:IAO_0000116 "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."@en ; obo:IAO_0000118 "has_participant"@en ; terms:source "http://www.obofoundry.org/ro/#OBO_REL:has_participant" ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "has participant"@en ; rdfs:range obo:BFO_0000002 . obo:RO_0000058 obo:IAO_0000112 "A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant)."@en, "An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process)."@en ; obo:IAO_0000115 "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants."@en ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000031 ; rdfs:label "is concretized as"@en ; rdfs:range obo:BFO_0000020 ; owl:inverseOf obo:RO_0000059 . obo:RO_0000059 obo:IAO_0000112 "A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant)."@en, "An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process)."@en ; obo:IAO_0000115 "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant."@en ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000020 ; rdfs:label "concretizes"@en ; rdfs:range obo:BFO_0000031 . obo:RO_0000079 obo:IAO_0000112 "this catalysis function is a function of this enzyme"@en ; obo:IAO_0000115 "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists."@en ; obo:IAO_0000118 "function_of"@en, "is function of"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ; rdfs:domain obo:BFO_0000034 ; rdfs:label "function of"@en ; rdfs:subPropertyOf obo:RO_0000052 ; owl:inverseOf obo:RO_0000085 . obo:RO_0000080 obo:IAO_0000112 "this red color is a quality of this apple"@en ; obo:IAO_0000115 "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A quality inheres in its bearer at all times for which the quality exists."@en ; obo:IAO_0000118 "is quality of"@en, "quality_of"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ; rdfs:label "quality of"@en ; rdfs:subPropertyOf obo:RO_0000052 ; owl:inverseOf obo:RO_0000086 . obo:RO_0000081 obo:IAO_0000112 "this investigator role is a role of this person"@en ; obo:IAO_0000115 "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists."@en ; obo:IAO_0000118 "is role of"@en, "role_of"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ; rdfs:label "role of"@en ; rdfs:subPropertyOf obo:RO_0000052 ; owl:inverseOf obo:RO_0000087 . obo:RO_0000085 obo:IAO_0000112 "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)"@en ; obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists."@en ; obo:IAO_0000118 "has_function"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000004 ; rdfs:label "has function"@en ; rdfs:range obo:BFO_0000034 ; rdfs:subPropertyOf obo:RO_0000053 . obo:RO_0000086 obo:IAO_0000112 "this apple has quality this red color"@en ; obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist."@en ; obo:IAO_0000118 "has_quality"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has quality"@en ; rdfs:range obo:BFO_0000019 ; rdfs:subPropertyOf obo:RO_0000053 . obo:RO_0000087 obo:IAO_0000112 "this person has role this investigator role (more colloquially: this person has this role of investigator)"@en ; obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists."@en ; obo:IAO_0000118 "has_role"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000004 ; rdfs:label "has role"@en ; rdfs:range obo:BFO_0000023 ; rdfs:subPropertyOf obo:RO_0000053 . obo:RO_0000091 obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000004 ; rdfs:label "has disposition"@en ; rdfs:range obo:BFO_0000016 ; rdfs:subPropertyOf obo:RO_0000053 ; owl:inverseOf obo:RO_0000092 . obo:RO_0000092 obo:IAO_0000115 "inverse of has disposition" ; obo:IAO_0000412 ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ; rdfs:label "disposition of"@en ; rdfs:subPropertyOf obo:RO_0000052 . obo:RO_0001000 obo:IAO_0000112 "this cell derives from this parent cell (cell division)"@en, "this nucleus derives from this parent nucleus (nuclear division)"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ; obo:IAO_0000116 "This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'."@en ; obo:IAO_0000118 "derives_from"@en ; a owl:ObjectProperty ; rdfs:label "derives from"@en ; owl:inverseOf obo:RO_0001001 . obo:RO_0001001 obo:IAO_0000112 "this parent cell derives into this cell (cell division)"@en, "this parent nucleus derives into this nucleus (nuclear division)"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity"@en ; obo:IAO_0000116 "This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'."@en ; obo:IAO_0000118 "derives_into"@en ; a owl:ObjectProperty ; rdfs:label "derives into"@en . obo:RO_0001015 obo:IAO_0000111 "is location of"@en ; obo:IAO_0000112 "my head is the location of my brain"@en, "this cage is the location of this rat"@en ; obo:IAO_0000115 "a relation between two independent continuants, the location and the target, in which the target is entirely within the location"@en ; obo:IAO_0000116 "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en ; obo:IAO_0000118 "location_of"@en ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "location of"@en ; owl:inverseOf obo:RO_0001025 . obo:RO_0001025 obo:IAO_0000111 "located in"@en ; obo:IAO_0000112 "my brain is located in my head"@en, "this rat is located in this cage"@en ; obo:IAO_0000115 "a relation between two independent continuants, the target and the location, in which the target is entirely within the location"@en ; obo:IAO_0000116 "Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus"@en, "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en ; obo:IAO_0000118 "located_in"@en ; obo:RO_0001900 obo:RO_0001901 ; terms:source "http://www.obofoundry.org/ro/#OBO_REL:located_in" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000004, [ a owl:Class ; owl:intersectionOf (obo:BFO_0000004 [ a owl:Class ; owl:complementOf obo:BFO_0000006 ] ) ] ; rdfs:label "located in"@en ; rdfs:range obo:BFO_0000004, [ a owl:Class ; owl:intersectionOf (obo:BFO_0000004 [ a owl:Class ; owl:complementOf obo:BFO_0000006 ] ) ] . obo:RO_0001900 obo:IAO_0000115 "An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context." ; a owl:AnnotationProperty ; rdfs:label "temporal interpretation" ; rdfs:seeAlso . obo:RO_0002000 obo:IAO_0000112 "the surface of my skin is a 2D boundary of my body"@en ; obo:IAO_0000115 "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity"@en ; obo:IAO_0000116 "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts."@en, "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape."@en ; obo:IAO_0000118 "2D_boundary_of"@en, "boundary of"@en, "is 2D boundary of"@en, "is boundary of"@en ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty ; rdfs:label "2D boundary of"@en ; owl:inverseOf obo:RO_0002002 . obo:RO_0002002 obo:IAO_0000112 "my body has 2D boundary the surface of my skin"@en ; obo:IAO_0000115 "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity"@en ; obo:IAO_0000116 "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts."@en, "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape."@en ; obo:IAO_0000118 "has boundary"@en, "has_2D_boundary"@en ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000040 ; rdfs:label "has 2D boundary"@en ; rdfs:range obo:BFO_0000141 . obo:RO_0002009 obo:IAO_0000115 "A relation that applies between a cell(c) and a gene(g) , where the process of 'transcription, DNA templated (GO_0006351)' is occuring in in cell c and that process has input gene g." ; obo:IAO_0000117 ; obo:IAO_0000412 ; terms:description """x 'cell expresses' y iff: cell(x) AND gene(y) AND exists some 'transcription, DNA templated (GO_0006351)'(t) AND t occurs_in x AND t has_input y""" ; a owl:ObjectProperty ; rdfs:label "cell expresses" ; rdfs:subPropertyOf obo:RO_0002292 . obo:RO_0002086 obo:IAO_0000117 "David Osumi-Sutherland" ; obo:IAO_0000412 ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ; rdfs:label "ends after"@en ; rdfs:subPropertyOf obo:RO_0002222 . obo:RO_0002091 obo:IAO_0000117 "David Osumi-Sutherland" ; obo:IAO_0000118 "io" ; obo:IAO_0000412 ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:comment "X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y))"@en ; rdfs:label "starts during"@en ; rdfs:subPropertyOf obo:RO_0002222 . obo:RO_0002092 obo:IAO_0000117 "David Osumi-Sutherland" ; obo:IAO_0000118 "d", "during" ; obo:IAO_0000412 ; oboInOwl:inSubset , , , ; a owl:ObjectProperty ; rdfs:comment "X happens_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (end(X) before_or_simultaneous_with end(Y))"@en ; rdfs:label "happens during"@en ; rdfs:seeAlso "https://wiki.geneontology.org/Happens_during"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002091, obo:RO_0002093 . obo:RO_0002093 obo:IAO_0000117 "David Osumi-Sutherland" ; obo:IAO_0000118 "o", "overlaps" ; obo:IAO_0000412 ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:comment "X ends_during Y iff: ((start(Y) before_or_simultaneous_with end(X)) AND end(X) before_or_simultaneous_with end(Y). "@en ; rdfs:label "ends during"@en ; rdfs:subPropertyOf obo:RO_0002222 . obo:RO_0002161 obo:IAO_0000112 "tooth SubClassOf 'never in taxon' value 'Aves'" ; obo:IAO_0000115 "x never in taxon T if and only if T is a class, and x does not instantiate the class expression \"in taxon some T\". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL." ; obo:IAO_0000117 ; obo:IAO_0000119 , ; obo:IAO_0000425 "Class: ?X DisjointWith: RO_0002162 some ?Y " ; obo:OMO_0002000 """PREFIX rdfs: PREFIX owl: PREFIX in_taxon: PREFIX never_in_taxon: CONSTRUCT { in_taxon: a owl:ObjectProperty . a owl:Restriction ; owl:onProperty in_taxon: ; owl:someValuesFrom ?taxon ] . ?x rdfs:subClassOf [ a owl:Restriction ; owl:onProperty in_taxon: ; owl:someValuesFrom [ a owl:Class ; owl:complementOf ?taxon ] ] . } WHERE { ?x never_in_taxon: ?taxon . }""" ; a owl:AnnotationProperty ; rdfs:label "never in taxon" ; rdfs:seeAlso . obo:RO_0002162 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed." ; obo:IAO_0000117 , ; obo:IAO_0000119 , ; obo:IAO_0000412 ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:comment "Connects a biological entity to its taxon of origin." ; rdfs:label "in taxon" ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002320 . obo:RO_0002171 obo:IAO_0000115 "A is mutually_spatially_disjoint_with B if both A and B are classes, and there exists no p such that p is part_of some A and p is part_of some B." ; obo:IAO_0000118 "non-overlapping with", "shares no parts with" ; obo:IAO_0000119 ; obo:IAO_0000425 "Class: EquivalentTo: (BFO_0000050 some ?X) and (BFO_0000050 some ?Y)" ; obo:OMO_0002000 """PREFIX owl: PREFIX part_of: PREFIX mutually_spatially_disjoint_with: CONSTRUCT { part_of: a owl:ObjectProperty . [ a owl:Restriction ; owl:onProperty part_of: ; owl:someValuesFrom ?x ; a owl:Restriction ; owl:onProperty part_of: ; owl:someValuesFrom ?y ] ] } WHERE { ?x mutually_spatially_disjoint_with: ?y . }""" ; a owl:AnnotationProperty ; rdfs:label "mutually spatially disjoint with"@en ; rdfs:seeAlso obo:RO_0002163, "https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern"^^xsd:anyURI . obo:RO_0002172 obo:IAO_0000115 "An assertion that holds between an ontology class and an organism taxon class, which is intepreted to yield some relationship between instances of the ontology class and the taxon." ; a owl:AnnotationProperty ; rdfs:label "taxonomic class assertion"@en ; rdfs:seeAlso . obo:RO_0002175 obo:IAO_0000115 "S present_in_taxon T if some instance of T has some S. This does not means that all instances of T have an S - it may only be certain life stages or sexes that have S" ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:OMO_0002000 """PREFIX rdfs: PREFIX owl: PREFIX in_taxon: PREFIX present_in_taxon: CONSTRUCT { in_taxon: a owl:ObjectProperty . ?witness rdfs:label ?label . ?witness rdfs:subClassOf ?x . ?witness rdfs:subClassOf [ a owl:Restriction ; owl:onProperty in_taxon: ; owl:someValuesFrom ?taxon ] . } WHERE { ?x present_in_taxon: ?taxon . BIND(IRI(CONCAT( \"http://purl.obolibrary.org/obo/RO_0002175#\", MD5(STR(?x)), \"-\", MD5(STR(?taxon)) )) as ?witness) BIND(CONCAT(STR(?x), \" in taxon \", STR(?taxon)) AS ?label) }""" ; a owl:AnnotationProperty ; rdfs:comment "The SPARQL expansion for this relation introduces new named classes into the ontology. For this reason it is likely that the expansion should only be performed during a QC pipeline; the expanded output should usually not be included in a published version of the ontology." ; rdfs:label "present in taxon"@en ; rdfs:seeAlso . obo:RO_0002180 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ; obo:IAO_0000116 "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity." ; obo:IAO_0000232 "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit."@en ; obo:IAO_0000412 ; obo:RO_0001900 obo:RO_0001901 ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:label "has component"@en ; rdfs:seeAlso ; rdfs:subPropertyOf obo:BFO_0000051 . obo:RO_0002204 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "definition \"x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x\"" ; obo:IAO_0000116 "We would like to be able to express the rule: if t transcribed from g, and t is a noncoding RNA and has an evolved function, then t has gene product g." ; obo:IAO_0000117 ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "gene product of"@en ; rdfs:subPropertyOf obo:RO_0002330 . obo:RO_0002205 obo:IAO_0000112 "every HOTAIR lncRNA is the gene product of some HOXC gene", "every sonic hedgehog protein (PR:000014841) is the gene product of some sonic hedgehog gene" ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y" ; obo:IAO_0000117 ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has gene product"@en ; rdfs:subPropertyOf obo:RO_0002330 . obo:RO_0002206 obo:IAO_0000112 "'neural crest cell' SubClassOf expresses some 'Wnt1 gene'" ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process" ; obo:IAO_0000117 ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "expressed in"@en ; rdfs:subPropertyOf obo:RO_0002330 . obo:RO_0002222 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000232 "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends." ; obo:IAO_0000412 ; terms:source "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1"^^xsd:anyURI ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ; rdfs:label "temporally related to"@en . obo:RO_0002245 obo:IAO_0000115 "g is over-expressed in t iff g is expressed in t, and the expression level of g is increased relative to some background." ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "over-expressed in" ; rdfs:subPropertyOf obo:RO_0002206 . obo:RO_0002246 obo:IAO_0000115 "g is under-expressed in t iff g is expressed in t, and the expression level of g is decreased relative to some background." ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "under-expressed in" ; rdfs:subPropertyOf obo:RO_0002206 . obo:RO_0002260 obo:IAO_0000115 "c has-biological-role r iff c has-role r and r is a biological role (CHEBI:24432)" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has biological role" ; rdfs:subPropertyOf obo:RO_0000087 . obo:RO_0002261 obo:IAO_0000115 "c has-application-role r iff c has-role r and r is an application role (CHEBI:33232)" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has application role" ; rdfs:subPropertyOf obo:RO_0000087 . obo:RO_0002262 obo:IAO_0000115 "c has-chemical-role r iff c has-role r and r is a chemical role (CHEBI:51086)" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "has chemical role" ; rdfs:subPropertyOf obo:RO_0000087 . obo:RO_0002291 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "x is ubiquitously expressed in y if and only if x is expressed in y, and the majority of cells in y express x" ; obo:IAO_0000116 "Revisit this term after coordinating with SO/SOM. The domain of this relation should be a sequence, as an instance of a DNA molecule is only expressed in the cell of which it is a part." ; obo:IAO_0000117 ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "ubiquitously expressed in"@en ; rdfs:subPropertyOf obo:RO_0002206 . obo:RO_0002292 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process." ; obo:IAO_0000117 ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "expresses"@en ; rdfs:subPropertyOf obo:RO_0002330 . obo:RO_0002293 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "inverse of ubiquiotously expressed in" ; obo:IAO_0000117 ; obo:IAO_0000412 ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:label "ubiquitously expresses"@en ; rdfs:subPropertyOf obo:RO_0002292 . obo:RO_0002314 obo:IAO_0000115 "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ; obo:IAO_0000116 "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of" ; obo:IAO_0000117 ; obo:IAO_0000118 "inheres in part of" ; obo:IAO_0000119 ; obo:IAO_0000412 ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty ; rdfs:label "characteristic of part of"@en ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002502 . obo:RO_0002320 obo:IAO_0000115 "A relationship that holds via some environmental process" ; obo:IAO_0000117 ; obo:IAO_0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution." ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "evolutionarily related to"@en . obo:RO_0002330 obo:IAO_0000115 "holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts." ; obo:IAO_0000117 ; obo:IAO_0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism" ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "genomically related to"@en . obo:RO_0002350 obo:IAO_0000112 "An organism that is a member of a population of organisms" ; obo:IAO_0000115 "is member of is a mereological relation between a item and a collection." ; obo:IAO_0000118 "is member of", "member part of" ; obo:IAO_0000119 "SIO" ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty ; rdfs:label "member of"@en ; rdfs:subPropertyOf obo:BFO_0000050 ; owl:inverseOf obo:RO_0002351 . obo:RO_0002351 obo:IAO_0000115 "has member is a mereological relation between a collection and an item." ; obo:IAO_0000119 "SIO" ; obo:RO_0001900 obo:RO_0001901 ; a owl:IrreflexiveProperty, owl:ObjectProperty ; rdfs:label "has member"@en ; rdfs:subPropertyOf obo:BFO_0000051 . obo:RO_0002416 obo:IAO_0000115 "An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL." ; a owl:AnnotationProperty ; rdfs:label "logical macro assertion"@en ; rdfs:seeAlso "http://purl.obolibrary.org/obo/ro/docs/shortcut-relations/"^^xsd:anyURI . obo:RO_0002420 obo:IAO_0000115 "A logical macro assertion whose domain is an IRI for a class" ; obo:IAO_0000116 "The domain for this class can be considered to be owl:Class, but we cannot assert this in OWL2-DL" ; a owl:AnnotationProperty ; rdfs:label "logical macro assertion on a class"@en . obo:RO_0002421 obo:IAO_0000115 "A logical macro assertion whose domain is an IRI for a property" ; a owl:AnnotationProperty ; rdfs:label "logical macro assertion on a property"@en . obo:RO_0002422 obo:IAO_0000115 "Used to annotate object properties to describe a logical meta-property or characteristic of the object property." ; a owl:AnnotationProperty ; rdfs:label "logical macro assertion on an object property"@en . obo:RO_0002502 obo:IAO_0000117 ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "depends on" ; rdfs:seeAlso obo:BFO_0000169 . obo:RO_0002503 obo:IAO_0000115 "q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2" ; obo:IAO_0000116 "This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C." ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "towards" ; rdfs:subPropertyOf obo:RO_0002502 . obo:RO_0002510 obo:IAO_0000115 "x is transcribed from y if and only if x is synthesized from template y" ; obo:IAO_0000117 ; obo:IAO_0000119 "http://www.ncbi.nlm.nih.gov/pubmed/20226267"^^xsd:anyURI ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "transcribed from" ; rdfs:subPropertyOf obo:RO_0002330 . obo:RO_0002511 obo:IAO_0000115 "inverse of transcribed from" ; obo:IAO_0000117 ; obo:IAO_0000119 "http://www.ncbi.nlm.nih.gov/pubmed/20226267"^^xsd:anyURI ; obo:IAO_0000412 ; oboInOwl:inSubset ; a owl:ObjectProperty ; rdfs:label "transcribed to" ; rdfs:subPropertyOf obo:RO_0002330 . obo:RO_0002512 obo:IAO_0000115 "x is the ribosomal translation of y if and only if a ribosome reads x through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces y" ; obo:IAO_0000117 ; obo:IAO_0000119 "http://www.ncbi.nlm.nih.gov/pubmed/20226267"^^xsd:anyURI ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "ribosomal translation of" ; rdfs:subPropertyOf obo:RO_0002330 . obo:RO_0002513 obo:IAO_0000115 "inverse of ribosomal translation of" ; obo:IAO_0000117 ; obo:IAO_0000119 "http://www.ncbi.nlm.nih.gov/pubmed/20226267"^^xsd:anyURI ; obo:IAO_0000412 ; a owl:ObjectProperty ; rdfs:label "ribosomally translates to" ; rdfs:subPropertyOf obo:RO_0002330 . obo:RO_0002601 obo:IAO_0000115 "A shortcut relationship that holds between two entities based on their identity criteria" ; a owl:AnnotationProperty ; rdfs:label "logical macro assertion involving identity" . obo:RO_0002602 obo:IAO_0000115 "A shortcut relationship between two entities x and y1, such that the intent is that the relationship is functional and inverse function, but there is no guarantee that this property holds." ; a owl:AnnotationProperty ; rdfs:label "in approximate one to one relationship with" . obo:RO_0002604 obo:IAO_0000112 "'anterior end of organism' is-opposite-of 'posterior end of organism'", "'increase in temperature' is-opposite-of 'decrease in temperature'" ; obo:IAO_0000115 "x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x)." ; a owl:AnnotationProperty ; rdfs:label "is opposite of" . obo:RO_0004096 a owl:ObjectProperty ; rdfs:comment "DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information." ; rdfs:label "DEPRECATED inheres in"@en ; owl:deprecated true . obo:RO_0004097 a owl:ObjectProperty ; rdfs:label "DEPRECATED bearer of"@en ; owl:deprecated true . obo:UBERON_0000004 obo:IAO_0000115 "The olfactory organ of vertebrates, consisting of nares, olfactory epithelia and the structures and skeletal framework of the nasal cavity." ; obo:IAO_0000412 ; obo:UBPROP_0000001 "Organ that is the specialized structure of the face that contains olfactory neurons. The peripheral olfactory organ is paired[ZFA:0000047].", "a protuberance in vertebrates that houses the nostrils, or nares, which admit and expel air for respiration in conjunction with the mouth. Behind the nose are the olfactory mucosa and the sinuses. Behind the nasal cavity, air next passes through the pharynx, shared with the digestive system, and then into the rest of the respiratory system. In humans, the nose is located centrally on the face; on most other mammals, it is on the upper tip of the snout[WP]. GO: The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)[Wikipedia:Nose].", "the organ that is specialized for smell and is part of the respiratory system" ; obo:UBPROP_0000008 "the structure of the nose varies across vertebrates. In tetrapods the nose is part of the respiratory system.[PMID:25312359]" ; oboInOwl:hasDbXref "BTO:0000840", "CALOHA:TS-2037", "EHDAA2:0001274", "EHDAA:1502", "EMAPA:16542", "EV:0100037", "EV:0100370", "FMA:46472", "GAID:77", "MA:0000281", "MAT:0000139", "MESH:D009666", "MIAA:0000139", "NCIT:C12756", "SCTID:181195007", "TAO:0000047", "UMLS:C0028429", "Wikipedia:Nose", "ZFA:0000047", "galen:Nose" ; oboInOwl:hasExactSynonym "nasal sac", "nose", "peripheral olfactory organ" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "nasus", "olfactory apparatus", "proboInOwlscis" ; oboInOwl:id "UBERON:0000004" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "nose" ; rdfs:subClassOf obo:UBERON_0000062, obo:UBERON_0004121 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/d/d0/Canine-nose.jpg"^^xsd:anyURI . obo:UBERON_0000042 obo:IAO_0000115 "Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer." ; obo:IAO_0000412 ; obo:UBPROP_0000001 "A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]", "a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]" ; obo:UBPROP_0000012 "in FMA, SM = mesothelium + connective tissue. It excludes the cavity. Serous sac = SM + cavity. Note that the SM is a subtype of wall in FMA." ; dc:contributor ; oboInOwl:hasDbXref "FMA:9581", "GAID:19", "MESH:D012704", "NCIT:C13169", "SCTID:362878009", "TAO:0005425", "UMLS:C0036760", "Wikipedia:Serous_membrane", "ZFA:0005425" ; oboInOwl:hasExactSynonym "tunica serosa", "wall of serous sac" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "serosa" ; oboInOwl:id "UBERON:0000042" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "serous membrane" ; rdfs:subClassOf obo:PR_000050567, obo:UBERON_0004120, obo:UBERON_0010000 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png"^^xsd:anyURI, "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png"^^xsd:anyURI . obo:UBERON_0000061 obo:IAO_0000115 "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_33208, obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "AAO:0010825", "AEO:0000003", "BILA:0000003", "CARO:0000003", "EHDAA2:0003003", "EMAPA:0", "FBbt:00007001", "FMA:305751", "FMA:67135", "GAID:781", "HAO:0000003", "MA:0003000", "MESH:D000825", "SCTID:362889002", "TAO:0000037", "TGMA:0001823", "VHOG:0001759", "XAO:0003000", "ZFA:0000037", "http://dbpedia.org/ontology/AnatomicalStructure" ; oboInOwl:hasExactSynonym "biological structure", "connected biological structure" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0000061" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "anatomical structure" ; rdfs:subClassOf obo:UBERON_0000465 . obo:UBERON_0000062 obo:IAO_0000115 "Anatomical structure that performs a specific function or group of functions [WP]." ; obo:IAO_0000412 ; obo:RO_0002161 obo:NCBITaxon_110815 ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_33208, obo:NCBITaxon_4751 ; obo:UBPROP_0000001 "Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; obo:UBPROP_0000012 "CARO v1 does not include a generic 'organ' class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4" ; oboInOwl:hasDbXref "BIRNLEX:4", "CARO:0020004", "EFO:0000634", "EMAPA:35949", "ENVO:01000162", "FMA:67498", "MA:0003001", "NCIT:C13018", "SCTID:272625005", "UMLS:C0178784", "WBbt:0003760", "Wikipedia:Organ_(anatomy)" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "anatomical unit", "body organ", "element" ; oboInOwl:id "UBERON:0000062" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "organ" ; rdfs:subClassOf obo:UBERON_0010000 . obo:UBERON_0000064 obo:IAO_0000115 "A multicellular structure that is a part of an organ." ; obo:IAO_0000232 "currently defined in a very broad sense, may be replaced by more specific classes in the future" ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_33208, obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "AAO:0011124", "BIRNLEX:16", "EFO:0000635", "FMA:82472", "SCTID:113343008", "SCTID:91717005" ; oboInOwl:hasExactSynonym "cardinal organ part" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "regional part of organ" ; oboInOwl:id "UBERON:0000064" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "organ part" ; rdfs:subClassOf obo:UBERON_0010000 . obo:UBERON_0000105 obo:IAO_0000115 "A spatiotemporal region encompassing some part of the life cycle of an organism." ; obo:IAO_0000116 "this class represents a proper part of the life cycle of an organism. The class 'life cycle' should not be placed here" ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_33208, obo:NCBITaxon_4751 ; obo:UBPROP_0000012 "the WBls class 'all stages' belongs here as it is the superclass of other WBls stages", "we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage" ; oboInOwl:hasDbXref "BILS:0000105", "EFO:0000399", "FBdv:00007012", "FMA:24120", "HsapDv:0000000", "MESH:D008018", "MmusDv:0000000", "OlatDv:0000010", "PdumDv:0000090", "WBls:0000002", "XAO:1000000", "ZFS:0000000", "ZFS:0100000", "ncithesaurus:Developmental_Stage" ; oboInOwl:hasNarrowSynonym "developmental stage", "stage" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0000105" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "life cycle stage" ; rdfs:subClassOf obo:BFO_0000003 . obo:UBERON_0000106 obo:IAO_0000115 "A stage at which the organism is a single cell produced by means of sexual reproduction." ; obo:IAO_0000412 ; obo:UBPROP_0000003 "As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG]" ; oboInOwl:hasDbXref "BILS:0000106", "BilaDO:0000005", "EFO:0001322", "EHDAA:27", "FBdv:00005288", "IDOMAL:0000302", "NCIT:C12601", "PdumDv:0000100", "VHOG:0000745", "Wikipedia:Zygote", "XAO:1000001", "ZFS:0000001" ; oboInOwl:hasExactSynonym "1-cell stage", "fertilized egg stage", "one cell stage" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "fertilized egg stage", "one-cell stage", "zygote", "zygotum" ; oboInOwl:id "UBERON:0000106" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "zygote stage" ; rdfs:seeAlso obo:EMAPA_16033 ; rdfs:subClassOf obo:UBERON_0000105 . obo:UBERON_0000165 obo:IAO_0000115 "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." ; obo:IAO_0000412 ; obo:UBPROP_0000001 "Cavity in which food is initially ingested and generally contains teeth, tongue and glands.[AAO]" ; obo:UBPROP_0000003 "Molecular and developmental cell lineage data suggest that the acoel mouth opening is homologous to the mouth of protostomes and deuterostomes and that the last common ancestor of the Bilateria (the 'urbilaterian') had only this single digestive opening.[well established][VHOG]" ; obo:UBPROP_0000007 "oral" ; obo:UBPROP_0000011 "some AOs place this as developing from the stomodeum but we weaken this to developmental contribution, as the mouth includes non-ectodermal derivatives" ; obo:UBPROP_0000012 "in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips" ; oboInOwl:hasDbXref "AAO:0010355", "BTO:0001090", "BTO:0004698", "CALOHA:TS-1315", "EFO:0000825", "EHDAA2:0001326", "EHDAA:542", "EMAPA:16262", "FBbt:00003126", "FMA:49184", "GAID:75", "MA:0000341", "MA:0002474", "MAT:0000038", "MESH:D009055", "MIAA:0000038", "SCTID:21082005", "TADS:0000040", "TAO:0000547", "TAO:0000590", "TGMA:0000131", "VHOG:0000280", "VHOG:0000812", "Wikipedia:Mouth", "XAO:0003029", "ZFA:0000547", "ZFA:0000590", "galen:Mouth", "http://purl.oboInOwllibrary.org/oboInOwl/uberon/images/lamprey_sucker_rosava_3238889218.jpg" ; oboInOwl:hasExactSynonym "regio oralis" ; oboInOwl:hasNarrowSynonym "adult mouth" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "cavital oralis", "cavitas oris", "cavum oris", "mouth cavity", "oral region", "oral vestibule", "rima oris", "stoma", "stomatodaeum", "trophic apparatus", "vestibule of mouth", "vestibulum oris" ; oboInOwl:id "UBERON:0000165" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "mouth" ; rdfs:seeAlso "https://github.com/obophenotype/uberon/issues/661"^^xsd:anyURI ; rdfs:subClassOf obo:UBERON_0004921 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/0/06/Mouth_illustration-Otis_Archives.jpg"^^xsd:anyURI . obo:UBERON_0000178 obo:IAO_0000115 "A fluid that is composed of blood plasma and erythrocytes." ; obo:IAO_0000232 "This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_9606 ; obo:UBPROP_0000001 "A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO]", "Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO]" ; obo:UBPROP_0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" ; obo:UBPROP_0000003 "Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG]" ; dc:contributor , ; oboInOwl:hasDbXref "AAO:0000046", "BTO:0000089", "CALOHA:TS-0079", "EFO:0000296", "EHDAA2:0000176", "EHDAA:418", "EMAPA:16332", "ENVO:02000027", "EV:0100047", "FMA:9670", "GAID:965", "MA:0000059", "MESH:D001769", "MIAA:0000315", "NCIT:C12434", "TAO:0000007", "UMLS:C0005767", "VHOG:0000224", "Wikipedia:Blood", "XAO:0000124", "ZFA:0000007", "galen:Blood" ; oboInOwl:hasExactSynonym "portion of blood", "vertebrate blood" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "whole blood" ; oboInOwl:id "UBERON:0000178" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "blood" ; rdfs:subClassOf obo:PR_000050567, obo:UBERON_0006314 . obo:UBERON_0000465 obo:IAO_0000115 "Anatomical entity that has mass." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_33208, obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "AAO:0010264", "AEO:0000006", "BILA:0000006", "CARO:0000006", "EHDAA2:0003006", "FBbt:00007016", "FMA:67165", "HAO:0000006", "TAO:0001836", "TGMA:0001826", "VHOG:0001721" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0000465" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "material anatomical entity" ; rdfs:subClassOf obo:BFO_0000040, obo:UBERON_0001062 . obo:UBERON_0000945 obo:IAO_0000115 "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." ; obo:IAO_0000412 ; obo:RO_0002161 obo:NCBITaxon_7864, obo:NCBITaxon_7878, obo:NCBITaxon_7955, obo:NCBITaxon_9259 ; obo:UBPROP_0000001 "Portion of alimentary canal with increased circular and longitudinal smooth muscle. Bounded posteriorly by the pyloric sphincter. Mucosal lining has increased folding.[AAO]" ; obo:UBPROP_0000003 "It appears that the stomach has an ancient origin. The stomach first appears in the fish lineage. The prevertebrate chordates do not have a true stomach, whereas the cartilaginous and bony fish do. Although most fish do have a true stomach, some fish species appear to have lost the stomach secondarily. The remaining vertebrate lineages do have a true stomach (at least in the adult animal), although there is great variation in the size and shape of the stomach.[well established][VHOG]" ; obo:UBPROP_0000008 "We restrict this to the vertebrate specific structure - see the grouping class 'food storage organ' for analogous structures in other species. Teleosts: Zebrafish is functionally stomach-less, but may retain ontogenic footprint. Although the precise shape and size of the stomach varies widely among different vertebrates, the relative positions of the oesophageal and duodenal openings remain relatively constant. As a result, the organ always curves somewhat to the left before curving back to meet the pyloric sphincter. However, lampreys, hagfishes, chimaeras, lungfishes, and some teleost fish have no stomach at all, with the oesophagus opening directly into the intestine. The gastric lining is usually divided into two regions, an anterior portion lined by fundic glands, and a posterior with pyloric glands. Cardiac glands are unique to mammals, and even then are absent in a number of species. The distributions of these glands vary between species, and do not always correspond with the same regions as in man. Furthermore, in many non-human mammals, a portion of the stomach anterior to the cardiac glands is lined with epithelium essentially identical to that of the oesophagus. Ruminants, in particular, have a complex stomach, the first three chambers of which are all lined with oesophageal mucosa" ; oboInOwl:hasDbXref "AAO:0000579", "ANISEED:1235297", "BTO:0001307", "CALOHA:TS-0980", "EFO:0000837", "EHDAA2:0001915", "EHDAA:2993", "EMAPA:17021", "EV:0100070", "FMA:7148", "GAID:293", "MA:0000353", "MAT:0000051", "MESH:D013270", "MIAA:0000051", "NCIT:C12391", "SCTID:181246003", "TAO:0002121", "UMLS:C0038351", "VHOG:0000408", "Wikipedia:Stomach", "XAO:0000128", "galen:Stomach" ; oboInOwl:hasNarrowSynonym "stomach chamber" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "anterior intestine", "gaster", "mesenteron", "ventriculus" ; oboInOwl:id "UBERON:0000945" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:label "stomach" ; rdfs:subClassOf obo:UBERON_0004921, obo:UBERON_0013765 ; foaf:depiction "https://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg"^^xsd:anyURI . obo:UBERON_0001044 obo:IAO_0000115 "Saliva-secreting exocrine glands of the oral cavity[GO]." ; obo:IAO_0000232 "currently we define saliva and salivary glands very generally in functional terms but it may be more appropriate to split this class. From WP: In most vertebrates, saliva does not contain any enzymes, consisting of mucus and water only, and its primary function is to moisten food while eating. As a result, true salivary glands are rarely found in fish or aquatic tetrapods, although there are often individual mucus-secreting cells. Amphibians have a single salivary gland, the intermaxillary gland, located in the forward part of the palate. Reptiles and birds normally have only very small glands on the lips, palate, and base of the mouth, although there are some birds with large glands, which produce a sticky saliva that helps in nest-building. The distinct parotid, submandibular, and sublingual glands are only developed in mammals." ; obo:IAO_0000412 ; obo:UBPROP_0000001 "A gland that produces the saliva. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-25, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" ; obo:UBPROP_0000003 "In air-feeding animals, the lack of water column to lubricate the food has been compensated for by the evolution of the salivary glands. These glands are present only in amniotes and are controlled by the parasympathetic system.[well established][VHOG]" ; obo:UBPROP_0000008 "The salivary glands in mammals are exocrine glands, glands with ducts, that produce saliva. They also secrete amylase, an enzyme that breaks down starch into maltose. In other organisms such as insects, salivary glands are often used to produce biologically important proteins like silk or glues, and fly salivary glands contain polytene chromosomes that have been useful in genetic research. The salivary glands of some species are modified to produce enzymes; salivary amylase is found in many, but by no means all, bird and mammal species (including humans, as noted above). Furthermore, the venom glands of poisonous snakes, Gila monsters, and some shrews, are modified salivary glands" ; oboInOwl:hasDbXref "BTO:0001203", "CALOHA:TS-0892", "EFO:0000859", "EHDAA2:0001775", "EHDAA:7987", "EMAPA:17751", "EV:0100059", "FBbt:00005382", "FMA:9597", "GAID:937", "MA:0000346", "MAT:0000079", "MESH:D012469", "MIAA:0000079", "NCIT:C12426", "SCTID:181236000", "UMLS:C0036098", "VHOG:0000376", "Wikipedia:Salivary_gland", "galen:SalivaryGland" ; oboInOwl:hasExactSynonym "salivary gland" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "glandulae salivariae" ; oboInOwl:id "UBERON:0001044" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "saliva-secreting gland" ; rdfs:subClassOf obo:UBERON_0010047 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/5/51/Illu_quiz_hn_02.jpg"^^xsd:anyURI . obo:UBERON_0001045 obo:IAO_0000115 "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]." ; obo:IAO_0000116 "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class" ; obo:IAO_0000412 ; obo:UBPROP_0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" ; obo:UBPROP_0000008 "In humans: originates from the foregut at the opening of the bile duct into the duodenum and continues through the small intestine and much of the large intestine until the transition to the hindgut about two-thirds of the way through the transverse colon" ; obo:UBPROP_0000012 "in FMA this represents an embryonic region." ; oboInOwl:hasDbXref "BILA:0000086", "BTO:0000863", "EFO:0001950", "EHDAA2:0001185", "EHDAA:983", "EMAPA:16255", "FBbt:00005383", "FMA:45617", "MA:0001564", "NCIT:C34210", "SCTID:361410004", "TGMA:0001036", "UMLS:C0231052", "VHOG:0000290", "Wikipedia:Midgut", "XAO:0000103" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "mesenteron" ; oboInOwl:id "UBERON:0001045" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "midgut" ; rdfs:subClassOf obo:UBERON_0004921 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg"^^xsd:anyURI . obo:UBERON_0001046 obo:IAO_0000115 "The caudalmost subdivision of a digestive tract." ; obo:IAO_0000116 "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future (vertebrates have some contribution from NC - https://github.com/obophenotype/uberon/wiki/The-neural-crest). We may explicitly make this a developmental class" ; obo:IAO_0000412 ; obo:UBPROP_0000001 "the caudal portion of the primitive digestive tube of the embryo" ; obo:UBPROP_0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" ; obo:UBPROP_0000012 "in FMA this class has no children. In MA it has a single child hindgut epithelium" ; oboInOwl:hasDbXref "AAO:0011052", "BILA:0000087", "BTO:0000510", "EHDAA2:0000779", "EHDAA:975", "EMAPA:16715", "FBbt:00005384", "FMA:45618", "MA:0001527", "NCIT:C34188", "SCTID:362856002", "TGMA:0001020", "UMLS:C0231053", "VHOG:0000459", "Wikipedia:Hindgut", "XAO:0000104" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "metenteron" ; oboInOwl:id "UBERON:0001046" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "hindgut" ; rdfs:subClassOf obo:UBERON_0004921 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png"^^xsd:anyURI . obo:UBERON_0001062 obo:IAO_0000115 "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_33208, obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "AAO:0010841", "AEO:0000000", "BILA:0000000", "BIRNLEX:6", "CARO:0000000", "EHDAA2:0002229", "FBbt:10000000", "FMA:62955", "HAO:0000000", "MA:0000001", "NCIT:C12219", "TAO:0100000", "TGMA:0001822", "UMLS:C1515976", "WBbt:0000100", "XAO:0000000", "ZFA:0100000" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0001062" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "anatomical entity" ; rdfs:subClassOf obo:BFO_0000004 . obo:UBERON_0001134 obo:IAO_0000115 "Muscle tissue that consists primarily of skeletal muscle fibers." ; obo:IAO_0000116 "TODO - add skeletal muscle organ? See GO:0060538 skeletal muscle organ development. Todo - group FBbt:00005073 - somatic muscle." ; obo:IAO_0000412 ; obo:UBPROP_0000001 "Muscle, composed of long cylindrical, multinucleated cells that attaches to the skeleton via tendons.[TAO]", "Tissue which consists of skeletal muscle fibers surrounded by endomysium. Examples: Skeletal muscle tissue of biceps, Skeletal muscle tissue of diaphragm[FMA]" ; obo:UBPROP_0000003 "This result implies the following views in terms of evolutionary differentiation: (1) Arthropod striated muscle and vertebrate skeletal and cardiac muscles share a common ancestor. In other words, they did not evolve independently (...) (5) The divergence of vertebrate skeletal and cardiac muscles/vertebrate smooth muscle and nonmuscle is at least before that of vertebrates/arthropods. In other words, emergence of skeletal and cardiac musle type tissues preceded the vertebrate/arthropod divergence (ca. 700 MYA).[well established][VHOG]" ; dc:contributor , , , ; oboInOwl:hasBroadSynonym "skeletal muscle" ; oboInOwl:hasDbXref "EMAPA:32716", "FMA:14069", "MA:0002439", "NCIT:C13050", "SCTID:426215008", "UMLS:C0242692", "Wikipedia:Skeletal_striated_muscle" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "skeletal muscle system", "somatic muscle" ; oboInOwl:id "UBERON:0001134" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "skeletal muscle tissue" ; rdfs:subClassOf obo:UBERON_0002385 ; foaf:depiction "https://upload.wikimedia.org/wikipedia/commons/c/c0/Skeletal_muscle.jpg"^^xsd:anyURI . obo:UBERON_0001255 obo:IAO_0000115 "Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." ; obo:IAO_0000412 ; obo:RO_0002161 obo:NCBITaxon_8782 ; obo:RO_0002175 obo:NCBITaxon_9606 ; obo:UBPROP_0000001 "A saccular organ in which urine accumulates before discharge from the body. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]", "Anatomical structure which consists of a membranous sac used to temporarily store urine until it is excreted from the body.[AAO]" ; obo:UBPROP_0000003 "In tetrapods, the urinary bladder arises as an outpocketing of the cloaca. (...) The tetrapod urinary bladder appears first among amphibians and is present in Sphenodon, turtles, most lizards, ostriches among birds, and all mammals.[well established][VHOG]" ; obo:UBPROP_0000007 "vesical" ; obo:UBPROP_0000008 "The urinary bladder evolved in tetrapods. Birds to not possess a true urinary bladder, although Palaeognathae have an undifferentiated cloacal outpocketing that serves a similar function[https://github.com/obophenotype/uberon/issues/454]" ; oboInOwl:hasBroadSynonym "bladder" ; oboInOwl:hasDbXref "AAO:0000623", "BTO:0001418", "CALOHA:TS-1090", "EFO:0000290", "EHDAA2:0000174", "EHDAA:9328", "EMAPA:18321", "EV:0100098", "FMA:15900", "GAID:0000004", "MA:0000380", "MAT:0000122", "MESH:D001743", "MIAA:0000122", "NCIT:C12414", "SCTID:302512001", "UMLS:C0005682", "VHOG:0000740", "Wikipedia:Urinary_bladder", "XAO:0000154", "galen:UrinaryBladder" ; oboInOwl:hasExactSynonym "vesica urinaria" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "urocyst", "vesica" ; oboInOwl:id "UBERON:0001255" ; oboInOwl:inSubset , , , , , ; a owl:Class ; rdfs:label "urinary bladder" ; rdfs:subClassOf obo:UBERON_0004120, obo:UBERON_0018707 ; foaf:depiction "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Urinary_Bladder.glb"^^xsd:anyURI, "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Urinary_Bladder.glb"^^xsd:anyURI, "https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg"^^xsd:anyURI . obo:UBERON_0001359 obo:IAO_0000115 "A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord." ; obo:IAO_0000116 "many sources state the CP as sole producer of CSF, but this is disputed [DOI:10.1007/s11064-015-1581-6]" ; obo:IAO_0000412 ; obo:UBPROP_0000001 "Portion of organism substance that is a clear fluid that occupies the subarachnoid space and the ventricular system around and inside the brain.[TAO]" ; obo:UBPROP_0000003 "In vertebrates, at early stages of Central Nervous System (CNS) development, the architecture of the brain primordium reveals the presence of the cavity of brain vesicles, which is filled by Embryonic Cerebro-Spinal Fluid (E-CSF). (...) Rat and chick E-CSF proteomes are similar, although rat is more complex in certain groups of proteins, e.g., apolipoproteins, which may be involved in the control of neural diversity, and has soluble enzymes present, just like adult human CSF, but unlike chick E-CSF, revealing phylogenetic brain differences between these groups of vertebrates.[uncertain][VHOG]" ; obo:UBPROP_0000012 "EHDAA2 models this as developing from CP, which is wrong", "the FMA def states that this is subarachnoid spaces only. ZFA def states subarachnoid spaces and brain ventricles, but not SC (and has part_of to brain). Circulation: It circulates from the lateral ventricles to the foramen of Monro (Interventricular foramen), third ventricle, aqueduct of Sylvius (Cerebral aqueduct), fourth ventricle, foramen of Magendie (Median aperture) and foramina of Luschka (Lateral apertures), subarachnoid space over brain and spinal cord. It should be noted that the CSF moves in a pulsatile manner throughout the CSF system with nearly zero net flow. CSF is reabsorbed into venous sinus blood via arachnoid granulations." ; oboInOwl:hasDbXref "BIRNLEX:1798", "BTO:0000237", "CALOHA:TS-0130", "EFO:0000329", "EHDAA2:0004441", "ENVO:02000029", "EV:0100311", "FMA:20935", "GAID:1181", "MA:0002503", "MAT:0000499", "MESH:D002555", "NCIT:C12692", "TAO:0002184", "UMLS:C0007806", "VHOG:0001278", "Wikipedia:Cerebrospinal_fluid", "ZFA:0001626" ; oboInOwl:hasExactSynonym "CSF", "cerebral spinal fluid" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "liquor cerebrospinalis", "spinal fluid" ; oboInOwl:id "UBERON:0001359" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "cerebrospinal fluid" ; rdfs:subClassOf obo:UBERON_0006314 . obo:UBERON_0001638 obo:IAO_0000115 "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." ; obo:IAO_0000116 "TODO - check with MA - vein vs venous blood vessel" ; obo:IAO_0000412 ; obo:UBPROP_0000001 "Part of the circulatory system composed of blood vessels which carry blood from other organs, tissues, and cells to the heart.[AAO]" ; obo:UBPROP_0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" ; obo:UBPROP_0000007 "venous" ; obo:UBPROP_0000202 obo:FMA_63814 ; oboInOwl:hasBroadSynonym "venous subtree", "venous vessel" ; oboInOwl:hasDbXref "AAO:0010212", "AEO:0000209", "BTO:0000234", "CALOHA:TS-1108", "EFO:0000816", "EHDAA2:0003254", "EMAPA:35906", "EV:0100031", "FMA:50723", "GAID:492", "MA:0000067", "MAT:0000037", "MESH:D014680", "MIAA:0000037", "NCIT:C12814", "SCTID:181367001", "TAO:0000082", "UMLS:C0042449", "VHOG:0001743", "Wikipedia:Vein", "XAO:0000115", "ZFA:0000082", "galen:Vein" ; oboInOwl:hasExactSynonym "venous tree organ part" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "vascular element", "vena", "venae" ; oboInOwl:id "UBERON:0001638" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "vein" ; rdfs:subClassOf obo:UBERON_0001981 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/c/c2/Venous_system_en.svg"^^xsd:anyURI . obo:UBERON_0001981 obo:IAO_0000115 "A vessel through which blood circulates in the body." ; obo:IAO_0000116 "consider adopting the EMAPA superclass 'vascular element', which includes microvasculature (e.g. capillaries), vascular plexus" ; obo:IAO_0000412 ; obo:UBPROP_0000001 "Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG]", "Any of the vessels through which blood circulates in the body.[AAO]" ; obo:UBPROP_0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" ; obo:UBPROP_0000008 "annelids have blood vessels, but this class is not applicable to annelids." ; obo:UBPROP_0000012 "FMA:63183 Blood vessel is categorized as 'general anatomical term'. Suggestion to map to region of vascular tree from Terry H at JAX" ; oboInOwl:hasBroadSynonym "vascular element" ; oboInOwl:hasDbXref "AAO:0011004", "AEO:0000207", "BTO:0001102", "CALOHA:TS-0080", "EFO:0000817", "EHDAA2:0003252", "EHDAA:240", "EMAPA:32743", "EMAPA:35993", "FMA:50722", "FMA:63183", "GAID:169", "MA:0000060", "MAT:0000393", "MESH:D001808", "NCIT:C12679", "NLXANAT:090901", "SCTID:361097006", "TAO:0002137", "UMLS:C0005847", "VHOG:0001250", "Wikipedia:Blood_vessel", "XAO:0001011", "ZFA:0005314" ; oboInOwl:hasExactSynonym "region of vascular tree organ", "vascular tree organ region" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "vas sanguineum" ; oboInOwl:id "UBERON:0001981" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "blood vessel" ; rdfs:subClassOf obo:PR_000050567, obo:UBERON_0004120, obo:UBERON_0010000 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg"^^xsd:anyURI . obo:UBERON_0002072 obo:IAO_0000115 "Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_9606 ; obo:UBPROP_0000001 "A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO]", "A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA:70544]." ; obo:UBPROP_0000007 "hypodermal", "subcutaneous", "subcutaneus" ; obo:UBPROP_0000012 "BTO has 'subcutis', as part of dermis. We follow FMA in having distinct classes for hypodermis and superficial fascia, and including these as part of the non-skin intgeument." ; oboInOwl:hasDbXref "BTO:0001314", "CALOHA:TS-2366", "EMAPA:37505", "FMA:70544", "NCIT:C33645", "TAO:0001136", "UMLS:C0278403", "Wikipedia:Hypodermis", "ZFA:0001136" ; oboInOwl:hasExactSynonym "hypoderm", "vertebrate hypodermis" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "sub-tegumental tissue", "subcutaneous tissue", "subcutis", "subtegumental tissue", "superficial fascia", "tela subcutanea" ; oboInOwl:id "UBERON:0002072" ; oboInOwl:inSubset , , , ; a owl:Class ; rdfs:label "hypodermis" ; rdfs:subClassOf obo:PR_000050567, obo:UBERON_0000064, obo:UBERON_0004120 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg"^^xsd:anyURI . obo:UBERON_0002097 obo:IAO_0000115 "The organ covering the body that consists of the dermis and epidermis." ; obo:IAO_0000232 "consider 'integumentary system' for invertebrates" ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_9606 ; obo:UBPROP_0000012 "MA uses the term skin to refer to what is called here: zone of skin" ; oboInOwl:hasDbXref "BTO:0001253", "CALOHA:TS-0934", "EFO:0000962", "EHDAA2:0001844", "EMAPA:17525", "FMA:7163", "MESH:D012867", "MFMO:0000099", "NCIT:C12470", "SCTID:181469002", "UMLS:C1123023", "Wikipedia:Skin", "XAO:0000023", "galen:Skin" ; oboInOwl:hasExactSynonym "entire skin", "skin organ" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "entire integument", "integument", "integumental organ", "pelt", "skin" ; oboInOwl:id "UBERON:0002097" ; oboInOwl:inSubset , , , , ; a owl:Class ; rdfs:label "skin of body" ; rdfs:subClassOf obo:PR_000050567, obo:UBERON_0000062, obo:UBERON_0004121 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg"^^xsd:anyURI, "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_F_Skin.glb"^^xsd:anyURI, "https://ccf-ontology.hubmapconsortium.org/objects/v1.0/VH_M_Skin.glb"^^xsd:anyURI, "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_F_Skin.glb"^^xsd:anyURI, "https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Skin.glb"^^xsd:anyURI, "https://ccf-ontology.hubmapconsortium.org/objects/v1.3/3d-vh-f-skin.glb"^^xsd:anyURI . obo:UBERON_0002358 obo:IAO_0000115 "A serous membrane that lines the peritoneal cavity[VHOG,modified]." ; obo:IAO_0000116 "TODO - in ZFA is_a epithelium" ; obo:IAO_0000412 ; obo:UBPROP_0000001 "An epithelium that lines the peritoneal cavity.[TAO]", "Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium.[AAO]" ; obo:UBPROP_0000007 "peritoneal" ; obo:UBPROP_0000012 "todo: check MA/EMAPA." ; oboInOwl:hasDbXref "AAO:0010814", "BTO:0001472", "CALOHA:TS-2072", "EV:0100087", "FMA:9584", "GAID:18", "MA:0000449", "MESH:D010537", "NCIT:C12770", "TAO:0005120", "UMLS:C0031153", "VHOG:0001257", "Wikipedia:Peritoneum", "XAO:0000139", "ZFA:0005120", "galen:Peritoneum" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "peritonaeum" ; oboInOwl:id "UBERON:0002358" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "peritoneum" ; rdfs:subClassOf obo:UBERON_0000042 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png"^^xsd:anyURI . obo:UBERON_0002365 obo:IAO_0000115 "A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas." ; obo:IAO_0000116 "Currently this is logically defined by the system it belongs to, but a better system may be base this on presence/absence of ducts. However, the dual nature of the liver should be taken into consideration here. Consider adding subclasses" ; obo:IAO_0000412 ; oboInOwl:hasDbXref "AEO:0000097", "BTO:0000765", "CALOHA:TS-2012", "EHDAA2:0003097", "EMAPA:35327", "FMA:9596", "GAID:34", "MA:0002564", "MESH:D005088", "NCIT:C12712", "SCTID:115976003", "UMLS:C0015282", "Wikipedia:Exocrine_gland" ; oboInOwl:hasExactSynonym "ducted gland", "glandula exocrina" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0002365" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "exocrine gland" ; rdfs:subClassOf obo:PR_000050567, obo:UBERON_0002530 . obo:UBERON_0002385 obo:IAO_0000115 "Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]." ; obo:IAO_0000412 ; obo:RO_0002171 obo:UBERON_0003714 ; obo:UBPROP_0000001 "One of the four types of tissue in traditional classifications. Tissue that contains cells with contractile filaments that move past each other and change the size of the cell. Muscle tissue also is separated into three distinct categories.[AAO]" ; oboInOwl:hasDbXref "AAO:0000306", "AEO:0000122", "CALOHA:TS-0642", "EHDAA2:0003122", "EMAPA:32715", "FMA:9641", "MA:0002437", "MESH:D009132", "NCIT:C12435", "SCTID:91727004", "UMLS:C2328219", "Wikipedia:Muscle_tissue", "galen:MuscleTissue" ; oboInOwl:hasExactSynonym "muscular tissue", "portion of muscle tissue", "textus muscularis" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0002385" ; oboInOwl:inSubset ; a owl:Class ; rdfs:comment "Vertebrate muscle is categorized into three major muscle types defined by their structural and functional properties: skeletal, cardiac and smooth. In Dmel the counterparts are somatic, heart/cardiac and visceral. Here we take a cell type based approach." ; rdfs:label "muscle tissue" ; rdfs:subClassOf obo:UBERON_0004120, obo:UBERON_0010000 . obo:UBERON_0002530 obo:IAO_0000115 "An organ that functions as a secretory or excretory organ." ; obo:IAO_0000412 ; obo:RO_0002171 obo:UBERON_0001434 ; obo:UBPROP_0000007 "glandular" ; oboInOwl:hasDbXref "AAO:0000212", "AEO:0000096", "BTO:0000522", "EFO:0000797", "EHDAA2:0003096", "EHDAA:2161", "EHDAA:4475", "EHDAA:6522", "EMAPA:18425", "FBbt:00100317", "FMA:7146", "FMA:86294", "HAO:0000375", "MA:0003038", "MAT:0000021", "MIAA:0000021", "NCIT:C13319", "SCTID:134358001", "UMLS:C1285092", "Wikipedia:Gland", "WikipediaCategory:Glands", "galen:Gland" ; oboInOwl:hasExactSynonym "glandular organ" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "Druese", "glandula" ; oboInOwl:id "UBERON:0002530" ; oboInOwl:inSubset , , ; a owl:Class ; rdfs:label "gland" ; rdfs:subClassOf obo:UBERON_0000062 ; foaf:depiction "http://upload.wikimedia.org/wikipedia/commons/a/a1/Gray1026.png"^^xsd:anyURI . obo:UBERON_0003408 obo:IAO_0000115 "A gland that is part of a digestive tract [Automatically generated definition]." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EMAPA:18815", "MA:0003202" ; oboInOwl:hasExactSynonym "digestive tract gland", "gland of digestive tract", "gland of lower gastrointestinal tract", "gut gland", "lower gastrointestinal tract gland" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0003408" ; a owl:Class ; rdfs:label "gland of digestive tract" ; rdfs:subClassOf obo:UBERON_0002530, obo:UBERON_0013765 . obo:UBERON_0004120 obo:IAO_0000115 "An anatomical structure that develops (entirely or partially) from the mesoderm." ; obo:IAO_0000232 "Grouping term for query purposes" ; obo:IAO_0000412 ; oboInOwl:hasExactSynonym "mesodermal derivative" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0004120" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "mesoderm-derived structure" ; rdfs:subClassOf obo:UBERON_0000061 . obo:UBERON_0004121 obo:IAO_0000115 "An anatomical structure that develops (entirely or partially) from the ectoderm." ; obo:IAO_0000232 "Grouping term for query purposes" ; obo:IAO_0000412 ; oboInOwl:hasExactSynonym "ectodermal deriviative" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0004121" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "ectoderm-derived structure" ; rdfs:subClassOf obo:UBERON_0000061 . obo:UBERON_0004921 obo:IAO_0000115 "A proximal-distal subdivision of the digestive tract." ; obo:IAO_0000232 "intended to denote both embryonic and adult structures. Note the FMA grouping here is not quite correct." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "FBbt:00100315", "FMA:71131" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "alimentary system subdivision", "gut section", "intestinal tract", "segment of intestinal tract", "subdivision of alimentary system" ; oboInOwl:id "UBERON:0004921" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "subdivision of digestive tract" ; rdfs:subClassOf obo:UBERON_0000064 . obo:UBERON_0006314 obo:IAO_0000115 "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." ; obo:IAO_0000412 ; oboInOwl:hasBroadSynonym "fluid" ; oboInOwl:hasDbXref "BIRNLEX:20", "EMAPA:37441", "FMA:280556", "GAID:266", "MESH:D001826", "Wikipedia:Body_fluid", "galen:BodyFluid" ; oboInOwl:hasExactSynonym "body fluid" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0006314" ; oboInOwl:inSubset ; a owl:Class ; rdfs:label "bodily fluid" ; rdfs:subClassOf obo:UBERON_0000465 . obo:UBERON_0010000 obo:IAO_0000115 "An anatomical structure that has more than one cell as a part." ; obo:IAO_0000412 ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_33208, obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "CARO:0010000", "FBbt:00100313" ; oboInOwl:hasExactSynonym "multicellular structure" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0010000" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "multicellular anatomical structure" ; rdfs:subClassOf obo:UBERON_0000061 . obo:UBERON_0010047 obo:IAO_0000115 "Gland of the epithelium lining the oral cavity. The most common are the salivary glands." ; obo:IAO_0000412 ; obo:UBPROP_0000012 "Note that Kardong classifies lacrimal glands here. EHDAA2 includes pituitary primordium, as this develops from oral mucosa" ; oboInOwl:hasAlternativeId "UBERON:0003293" ; oboInOwl:hasDbXref "EHDAA2:0001327", "EHDAA:2181", "EMAPA:16572", "EMAPA:16723", "VHOG:0000652" ; oboInOwl:hasNarrowSynonym "buccal gland" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:hasRelatedSynonym "gland of oral opening", "gland of oral region", "mouth gland", "oral cavity gland", "oral region gland" ; oboInOwl:id "UBERON:0010047" ; a owl:Class ; rdfs:label "oral gland" ; rdfs:subClassOf obo:UBERON_0002365, obo:UBERON_0003408 . obo:UBERON_0013765 obo:IAO_0000115 "Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "EMAPA:37843", "SCTID:272627002" ; oboInOwl:hasExactSynonym "digestive organ", "digestive system organ" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0013765" ; oboInOwl:inSubset , ; a owl:Class ; rdfs:label "digestive system element" ; rdfs:subClassOf obo:UBERON_0000062 . obo:UBERON_0018707 obo:IAO_0000115 "A membranous sac in animals that serves as the receptacle of a liquid or contains gas." ; obo:IAO_0000412 ; oboInOwl:hasDbXref "BTO:0000123" ; oboInOwl:hasNarrowSynonym "bladder" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "UBERON:0018707" ; a owl:Class ; rdfs:label "bladder organ" ; rdfs:subClassOf obo:UBERON_0000062 . obo:UBPROP_0000001 a owl:AnnotationProperty ; rdfs:label "external_definition" . obo:UBPROP_0000002 a owl:AnnotationProperty ; rdfs:label "axiom_lost_from_external_ontology" . obo:UBPROP_0000003 a owl:AnnotationProperty ; rdfs:label "homology_notes" . obo:UBPROP_0000007 a owl:AnnotationProperty ; rdfs:label "has_relational_adjective" . obo:UBPROP_0000008 a owl:AnnotationProperty ; rdfs:label "taxon_notes" . obo:UBPROP_0000011 a owl:AnnotationProperty ; rdfs:label "development_notes" . obo:UBPROP_0000012 a owl:AnnotationProperty ; rdfs:label "external_ontology_notes" . obo:UBPROP_0000202 a owl:AnnotationProperty ; rdfs:label "fma_set_term" . obo:VO_0000000 obo:IAO_0000115 "A pathogen component in vaccine that contains only a part of the pathogen organism instead of the whole organism." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "part of pathogen organism in vaccine" ; rdfs:subClassOf obo:VO_0000420, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:OBI_0100026 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000420 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:OBI_0100026 ] ) ] . obo:VO_0000001 obo:IAO_0000115 "A vaccine is a processed material with the function that when administered, it prevents or ameliorates a disorder in a target organism by inducing or modifying adaptive immune responses specific to the antigens in the vaccine." ; obo:IAO_0000116 "Many vaccines are developed to protect against infectious pathogens that causes infectious diseases. Many vaccines are also being developed against other diseases such as cancer, allergy, and autoimmune diseases." ; obo:IAO_0000117 "YH, BP, BS, MC, LC, XZ, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccine" ; rdfs:seeAlso "MeSH: D014612" ; rdfs:subClassOf obo:OBI_0000047, [ a owl:Restriction ; owl:onProperty obo:RO_0000085 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:VO_0000278 [ a owl:Restriction ; owl:onProperty obo:BFO_0000054 ; owl:someValuesFrom obo:VO_0000494 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000615 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000615 ] . obo:VO_0000002 obo:IAO_0000115 "a process of administering substance in vivo that involves in adding a vaccine into a host (e.g., human) in vivo with the intent to invoke a protective or therapeutic adaptive immune response." ; obo:IAO_0000117 "YH, BP" ; obo:IAO_0000118 "vaccine administration" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccination" ; rdfs:subClassOf obo:OBI_0600007, [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000319 [ a owl:Restriction ; owl:onProperty obo:RO_0000081 ; owl:someValuesFrom obo:VO_0000001 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000444 [ a owl:Restriction ; owl:onProperty obo:RO_0000081 ; owl:someValuesFrom obo:OBI_0100026 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:VO_0000001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001274 ] ) ] ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OBI_0600007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000319 [ a owl:Restriction ; owl:onProperty obo:RO_0000081 ; owl:someValuesFrom obo:VO_0000001 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0000444 [ a owl:Restriction ; owl:onProperty obo:RO_0000081 ; owl:someValuesFrom obo:OBI_0100026 ] ) ] ] ) ] . obo:VO_0000003 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/833083", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm180810.htm" ; obo:VO_0003099 "ACAM2000" ; obo:VO_0003158 "Smallpox (Vaccinia) Vaccine, Live" ; obo:VO_0003159 "Emergent Product Development Gaithersburg, Inc." ; obo:VO_0003160 "Active immunization against smallpox disease for persons determined to be at high risk for smallpox infection." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142572.pdf" ; obo:VO_0003162 "BL 125158" ; obo:VO_0003198 "833083" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ACAM2000" ; rdfs:seeAlso "CVX: 75" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004854 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003052 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000686 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000004 obo:IAO_0000116 """Preparation: The vaccine consists of the Haemophilus b capsular polysaccharide (polyribosyl-ribitol-phosphate, PRP), a high molecular weight polymer prepared from the Haemophilus influenzae type b (HiB) strain 1482 grown in a semi-synthetic medium, covalently bound to tetanus toxoid. The tetanus toxoid is prepared by extraction, ammonium sulfate purification, and formalin inactivation of the toxin from cultures of Clostridium tetani (Harvard strain) grown in a modified Mueller and Miller medium. The toxoid is filter sterilized prior to the conjugation process. When ActHIB vaccine is reconstituted with saline diluent, each single dose of 0.5 mL is formulated to contain 10 mu g of purified capsular polysaccharide conjugated to 24 mu g of inactivated tetanus toxoid, and 8.5% of sucrose (ActHIB 2005). Reference: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=157&keywords=""" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm174743.htm" ; obo:VO_0003099 "ActHIB" ; obo:VO_0003158 "Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)" ; obo:VO_0003160 "ActHIB vaccine is indicated for the active immunization of infants and children 2 months through 5 years of age for the prevention of invasive disease caused by H influenzae type b." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM109841.pdf" ; obo:VO_0003162 "103935" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ActHIB" ; rdfs:seeAlso "CVX: 48", "PMID:", "PMID: 1517908", "PMID: 1735812" ; rdfs:subClassOf obo:VO_0000662, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001254 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003049 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000703 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000005 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/605718", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm172481.htm" ; obo:VO_0003099 "Adacel" ; obo:VO_0003158 "Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed" ; obo:VO_0003160 "Booster immunization against tetanus, diphtheria and pertussis as a single dose in individuals 10 through 64 years of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142764.pdf" ; obo:VO_0003162 "BL 125111" ; obo:VO_0003198 "605718" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Adacel" ; rdfs:seeAlso "CVX: 115", "CVX: 20" ; rdfs:subClassOf obo:VO_0000738, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003199 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003201 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003202 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003384 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003455 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000006 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094043.htm" ; obo:VO_0003099 "AFLURIA" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003159 "Seqirus Pty. Ltd" ; obo:VO_0003160 "For active immunization of persons ages 6 months of age and older against influenza disease caused by influenza virus subtypes A and type B present in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM263239.pdf" ; obo:VO_0003162 "BL 125254" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Afluria" ; rdfs:seeAlso "CVX: 140", "CVX: 141" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000689 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:VO_0000908 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ] . obo:VO_0000007 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Measles Virus Vaccine, Live", "Trade Name: Attenuvax" ; rdfs:label "Attenuvax" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000654, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000008 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced lymphocyte activation" ; rdfs:subClassOf obo:VO_0000361 . obo:VO_0000009 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced B cell antigen processing and presentation" ; rdfs:subClassOf obo:VO_0000012 . obo:VO_0000010 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced B cell cytokine production" ; rdfs:subClassOf obo:VO_0000012 . obo:VO_0000011 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B cell epitope in vaccine" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccine B cell epitope" ; rdfs:subClassOf obo:VO_0000811 . obo:VO_0000012 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced B cell mediated immunity" ; rdfs:subClassOf obo:VO_0000135 . obo:VO_0000013 obo:IAO_0000115 "A vaccine that protects against Bacillus anthrax that causes anthrax." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "anthrax vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bacillus anthracis vaccine" ; rdfs:seeAlso "MeSH: D022122" ; rdfs:subClassOf obo:VO_0003536, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0000014 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/404894", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm133822.htm" ; obo:VO_0003099 "Biothrax" ; obo:VO_0003158 "Anthrax Vaccine Adsorbed" ; obo:VO_0003159 "Emergent BioDefense Operations Lansing LLC" ; obo:VO_0003160 "For the active immunization for the prevention of disease caused by Bacillus anthracis in persons between 18 and 65 years of age at high risk of exposure." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/BloodBloodProducts/ApprovedProducts/LicensedProductsBLAs/UCM074923.pdf" ; obo:VO_0003162 "BL 103821" ; obo:VO_0003198 "404894" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Biothrax" ; rdfs:seeAlso "CVX: 24" ; rdfs:subClassOf obo:VO_0000013, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004208 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000688 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000015 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/583411", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm172925.htm" ; obo:VO_0003099 "Boostrix" ; obo:VO_0003158 "Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed" ; obo:VO_0003160 "Booster immunization against tetanus, diphtheria and pertussis as a single dose in individuals 10 years of age and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/UCM152842.pdf" ; obo:VO_0003162 "BL 125106" ; obo:VO_0003198 "583411" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Boostrix" ; rdfs:seeAlso "CVX: 115", "CVX: 20" ; rdfs:subClassOf obo:VO_0000738, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003199 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003201 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003384 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003455 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000016 obo:IAO_0000115 "A type of 'has vaccine component' relation that specifies a vaccine conjugate protein for a specific vaccine" ; a owl:ObjectProperty ; rdfs:label "has vaccine conjugate protein" ; rdfs:subPropertyOf obo:VO_0000520 . obo:VO_0000017 obo:IAO_0000115 "whole organism vaccine that uses killed pathogen organism as its component." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "killed vaccine" ; rdfs:subClassOf obo:VO_0000315, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] . obo:VO_0000018 obo:IAO_0000115 "A Brucella abortus vaccine that expresses Cu/Zn SOD with DNA plasmid pcDNA. PMID: 15039330." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus DNA vaccine pcDNA-SOD" ; rdfs:seeAlso "PMID: 15039330" ; rdfs:subClassOf obo:VO_0001225, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0000154 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000019 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVAX DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000020 obo:IAO_0000115 "A bacterial vaccine vector that uses B. abortus vaccine strain RB51 as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Brucella abortus strain RB51 vaccine vector" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0000021 obo:IAO_0000115 "Brucella abortus vaccine RB51 is a Brucella abortus vaccine that is licensed in the USA since 1992." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus RB51", "Brucella RB-51", "Brucella RB51", "SRB51" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus vaccine RB51" ; rdfs:seeAlso "PMID: 10534009", "PMID: 11193615", "PMID: 11500423", "PMID: 11504226", "PMID: 11504238", "PMID: 11553603", "PMID: 11768128", "PMID: 12119140", "PMID: 12438380", "PMID: 12704101", "PMID: 1439207", "PMID: 16713034", "PMID: 17653832", "PMID: 17894637", "PMID: 18836016", "PMID: 1908158", "PMID: 19362381", "PMID: 19439382", "PMID: 7622248", "PMID: 7806364", "PMID: 7927779", "PMID: 8039890", "PMID: 8740701", "PMID: 8890203", "WEB: http://rb51.com" ; rdfs:subClassOf obo:VO_0001134, [ a owl:Restriction ; owl:onProperty obo:VO_0000799 ; owl:someValuesFrom obo:VO_0000794 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_391902 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9901 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000022 obo:IAO_0000115 "A live attenuated Brucella abortus vaccine that is licensed and used in many countries." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Brucella S19", "Brucella strain-19" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus vaccine strain 19" ; rdfs:seeAlso "PMID: 11058778", "PMID: 8039890" ; rdfs:subClassOf obo:VO_0001134, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0000023 obo:IAO_0000117 "YH, ZX" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Invitrogen" . obo:VO_0000024 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVAX1 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000025 obo:IAO_0000115 "A vaccine that protects against Brucella that causes brucellosis in animals and humans." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "brucellosis vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella vaccine" ; rdfs:seeAlso "MeSH: D002004" ; rdfs:subClassOf obo:VO_0003550, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0000026 obo:IAO_0000117 "YH, ZX" ; oboInOwl:hasAlternativeId "VO:0000217" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV4 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000027 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pAp031 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000028 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/139056" ; obo:VO_0003198 "139056" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate) & Hepatitis B Vaccine (Recombinant)", "Trade Name: Comvax" ; rdfs:label "Comvax" ; rdfs:seeAlso "CVX: 51", "PMID:" ; rdfs:subClassOf obo:VO_0000746, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003150 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003408 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000029 obo:IAO_0000116 "Vaccine components see http://www.vaccinesafety.edu/components-DTaP.htm" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/352572", "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM241874.pdf" ; obo:VO_0003099 "DAPTACEL" ; obo:VO_0003158 "Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed" ; obo:VO_0003160 "Indicated for active immunization against diphtheria, tetanus and pertussis as a five dose series in infants and children 6 weeks through 6 years of age (prior to 7th birthday)." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM103037.pdf" ; obo:VO_0003162 "103666" ; obo:VO_0003198 "352572" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Daptacel" ; rdfs:seeAlso "CVX: 106", "CVX: 20" ; rdfs:subClassOf obo:VO_0000738, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003199 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003201 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003202 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003384 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003455 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000030 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Tetanus & Diphtheria Toxoids Adsorbed for Adult Use", "Trade Name: DECAVAC" ; rdfs:label "DECAVAC" ; rdfs:seeAlso "CVX: 113" ; rdfs:subClassOf obo:VO_0000732, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000031 obo:IAO_0000115 "A vaccine for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroups C and Y and Haemophilus influenzae type b. MENHIBRIX is approved for use in children 6 weeks of age through 18 months of age. " ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1437912", "https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm308566.htm" ; obo:VO_0003099 "MenHibrix" ; obo:VO_0003158 "Meningococcal Groups C and Y and Haemophilus b Tetanus Toxoid Conjugate Vaccine" ; obo:VO_0003160 "Indicated for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroups C and Y and Haemophilus influenzae type b for children 6 weeks of age through 18 months of age." ; obo:VO_0003162 "BL 125363/0" ; obo:VO_0003198 "1437912" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MenHibrix" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000662, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004859 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004860 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015013 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000032 obo:IAO_0000115 "DNA vaccine is a vaccine that is composed of a plasmid vaccine vector (a circular double stranded DNA molecule) containing genes encoding one or more proteins of a pathogen." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "genetic vaccine", "naked DNA vaccine", "nucleic acid vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ] . obo:VO_0000033 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Diphtheria & Tetanus Toxoids Adsorbed" ; rdfs:label "Diphtheria and Tetanus Toxoids Adsorbed USP by Sanofi Pasteur Inc" ; rdfs:seeAlso "CVX: 28" ; rdfs:subClassOf obo:VO_0000732, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000034 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0000033 ; a owl:Class ; rdfs:comment "Product Name: Diphtheria & Tetanus Toxoids Adsorbed", "This term is obsolete since there is another term with the same meaning." ; rdfs:label "obsolete Diphtheria and Tetanus Toxoids Adsorbed by Sanofi Pasteur Ltd" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000035 obo:IAO_0000115 "a vaccinia virus vaccine that is a freeze-dried calf lymph smallpox vaccine, specifically, Dryvax is a live-virus preparation of vaccinia prepared from calf lymph. " ; obo:IAO_0000116 "Dryvax is a freeze-dried calf lymph smallpox vaccine. It is the world's oldest smallpox vaccine, created in the late 19th century by American Home Products, a predecessor of Wyeth. By the 1940s, Wyeth was the leading US manufacturer of the vaccine and the only manufacturer by the 1960s. After world health authorities declared smallpox had been eradicated from nature in 1980, Wyeth stopped making the vaccine." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "http://en.wikipedia.org/wiki/Dryvax" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Smallpox Vaccine, Dried, Calf Lymph Type", "Trade Name: Dryvax" ; rdfs:label "Dryvax" ; rdfs:seeAlso "CVX: 75" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000036 obo:IAO_0000115 "ACAM2007 is a vaccine candidate expressing CFA/II." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095642/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ETEC vaccine ACAM2010" ; rdfs:seeAlso "PMID: 17566016" ; rdfs:subClassOf obo:VO_0000619, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000037 obo:IAO_0000115 "A viral vaccine that protects against infection of an adenovirus." ; obo:IAO_0000117 "YH, SGS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "adenovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10508 ] . obo:VO_0000038 obo:IAO_0000115 "An assay that measures the persistent survival of live vaccine in a host in vivo." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "vaccine persistence assay" ; rdfs:subClassOf obo:OBI_0000070 . obo:VO_0000039 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pBacPAK9 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000040 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pBC12/CMV DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000041 obo:IAO_0000115 "A bacterial vaccine that prevents against Escherichia coli infection." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "E. coli vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Escherichia coli vaccine" ; rdfs:seeAlso "MeSH: D022361" ; rdfs:subClassOf obo:VO_0003552, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_562 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_562 ] . obo:VO_0000042 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pBHT DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000043 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112845.htm" ; obo:VO_0003099 "FluLaval" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003160 "Active immunization for the prevention of disease caused by influenza A subtype viruses and type B virus contained in the vaccine. FLULAVAL is approved for use in persons 6 months of age and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM112904.pdf" ; obo:VO_0003162 "BL 125163" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Influenza Virus Vaccine, Trivalent, Types A and B" ; rdfs:label "FluLaval" ; rdfs:seeAlso "CVX: 141" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0002498 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000044 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094047.htm" ; obo:VO_0003099 "FluMist" ; obo:VO_0003158 "Influenza Vaccine Live, Intranasal" ; obo:VO_0003160 "For the active immunization of individuals 2-49 years of age against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine." ; obo:VO_0003162 "BL 125020" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FluMist" ; rdfs:seeAlso "CVX: 111" ; rdfs:subClassOf obo:VO_0001178, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000343 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000694 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000045 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112850.htm" ; obo:VO_0003099 "Fluarix" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003160 "For active immunization of persons 3 years of age and older for the prevention of disease caused by influenza virus subtypes A and type B contained in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM335392.pdf" ; obo:VO_0003162 "BL 125127" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluarix" ; rdfs:seeAlso "CVX: 140" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000046 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112852.htm" ; obo:VO_0003099 "Fluvirin" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003159 "Seqirus Vaccines Limited" ; obo:VO_0003160 "For active immunization of persons 4 years of age and older against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM123694.pdf" ; obo:VO_0003162 "BL 103837" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Influenza Virus Vaccine, Trivalent, Types A and B" ; rdfs:label "Fluvirin" ; rdfs:seeAlso "CVX: 140", "CVX: 141" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000696 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000047 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.htm" ; obo:VO_0003099 "Fluzone" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003160 "Fluzone is indicated for active immunization of persons 6 months of age and older against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM619664.pdf" ; obo:VO_0003162 "BL 103914" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Influenza Virus Vaccine, Trivalent, Types A and B" ; rdfs:label "Fluzone" ; rdfs:seeAlso "CVX: 140", "CVX: 141", "CVX: 144" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000048 obo:IAO_0000115 "A gene that once deleted, would make an attenuated microbe that can be used as a live attenuated vaccine against virulent pathogen." ; obo:IAO_0000117 "YH, YL, ZX" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "virmugen" ; rdfs:subClassOf obo:OGG_0000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0000049 obo:IAO_0000116 """Gardasil is a quadrivalent vaccine meaning it protects against 4 strains of virus (types 6, 11, 16, and 18). The vaccine was made using genetic engineering techniques. The genes that encode a specific protein from each of these strains are expressed in yeast in large-scale fermentation cultures. Protein purification methods are then used to isolate the proteins and make the vaccine. Cited from: http://biotech.about.com/b/2008/09/03/gardasil-safety-of-genetically-engineered-hpv-vaccine-still-in-question.htm""" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/659877", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094042.htm" ; obo:VO_0003099 "Gardasil" ; obo:VO_0003158 "Human Papillomavirus Quadrivalent (Types 6, 11, 16, 18) Vaccine, Recombinant" ; obo:VO_0003160 """- Prevention of vulvar and vaginal cancer - Vaccination in females 9 through 26 years of age for prevention of the following diseases caused by Human Papillomavirus (HPV) Types 6, 11, 16, and 18: - Cervical Cancer - Genital warts (condyloma acuminata) and the following precancerous or dysplastic lesions: - Cervical adenocarcinoma in situ (AIS)cancer - Cervical intraepithelial neoplasia (CIN) grade 2 and grade 3 - Vulvar intraepithelial neoplasia (VIN) grade 2 and grade 3 - Vaginal intraepithelial neoplasia (VaIN) grade 2 and grade 3 - Cervical intraepithelial neoplasia (CIN) grade 1 - Vaccination in boys and men 9 through 26 years of age for the prevention of genital warts caused by HPV types 6 and 11 - Vaccination in people ages 9 through 26 years for the prevention of anal cancer and associated precancerous lesions due to human papillomavirus (HPV) types 6, 11, 16, and 18""" ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM111263.pdf" ; obo:VO_0003162 "125126" ; obo:VO_0003198 "659877" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Gardasil" ; rdfs:seeAlso "CVX: 62" ; rdfs:subClassOf obo:VO_0000667, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003300 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003301 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003302 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003303 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000050 obo:IAO_0000115 "a lentivirus vaccine vector that uses a HIV strain as the vector" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "HIV based lentivirus vaccine vector" ; rdfs:subClassOf obo:VO_0000359 . obo:VO_0000051 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "Balb/c mouse" ; rdfs:subClassOf obo:NCBITaxon_10090 . obo:VO_0000052 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/203439", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm110016.htm" ; obo:VO_0003099 "HAVRIX" ; obo:VO_0003158 "Hepatitis A Vaccine, Inactivated" ; obo:VO_0003160 "For active immunization against disease caused by hepatitis A virus (HAV) for persons 12 months of age and older." ; obo:VO_0003161 "BL 103475", "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM224555.pdf" ; obo:VO_0003198 "203439" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Havrix" ; rdfs:seeAlso "CVX: 52", "CVX: 83" ; rdfs:subClassOf obo:VO_0000646, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003433 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000053 obo:IAO_0000115 "A bacterial vaccine that prevents Neisseria meningitidis infection." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Meningococcal vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neisseria meningitidis vaccine" ; rdfs:seeAlso "MeSH: D022401" ; rdfs:subClassOf obo:VO_0003484, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000165 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] ) ] . obo:VO_0000054 obo:IAO_0000115 "IPOL, Poliovirus Vaccine Inactivated is a sterile suspension of three types of poliovirus: Type 1 (Mahoney), Type 2 (MEF-1), and Type 3 (Saukett). IPOL vaccine is a highly purified, inactivated poliovirus vaccine with enhanced potency." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/287617", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm180053.htm" ; obo:VO_0003099 "IPOL" ; obo:VO_0003158 "Poliovirus Vaccine Inactivated (Monkey Kidney Cell)" ; obo:VO_0003160 "IPOL vaccine is indicated for active immunization of infants (as young as 6 weeks of age), children and adults for the prevention of poliomyelitis caused by poliovirus Types 1, 2, and 3." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM133479.pdf" ; obo:VO_0003162 "103930" ; obo:VO_0003198 "287617" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IPOL" ; rdfs:seeAlso "CVX: 10", "PMID:" ; rdfs:subClassOf obo:VO_0000664, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003835 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003836 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003837 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000703 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000055 obo:IAO_0000115 "The jourmal article that mentions a vaccine, which was retrieved from PubMed and annotated using VO-SciMinner.(Hur J, Xiang Z, Feldman EL, He Y. Ontology-based Brucella vaccine literature indexing and systematic analysis of gene-vaccine association network. BMC Immunology. 12(1):49 2011 Aug 26. PMID: 21871085.)" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "vaccine related journal article" ; rdfs:subClassOf obo:IAO_0000013, [ a owl:Restriction ; owl:onProperty obo:IAO_0000142 ; owl:someValuesFrom obo:VO_0000001 ] . obo:VO_0000056 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "United Vaccines, Inc" . obo:VO_0000057 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Heska Corporation" . obo:VO_0000058 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Texas Vet lab, Inc" . obo:VO_0000059 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "SolidTech Animal Health, Inc" . obo:VO_0000060 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "MVP Laboratories, Inc" . obo:VO_0000061 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Addison Biological Laboratory, Inc" . obo:VO_0000062 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Neotech, LLC" ; rdfs:seeAlso "neotechvaccines.com" . obo:VO_0000063 obo:IAO_0000115 "The Imovax¬Æ 9 Rabies Vaccine is a sterile, stable, freeze-dried 10 suspension of rabies virus prepared from strain PM-1503-3M." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659730", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm180097.htm" ; obo:VO_0003099 "IMOVAX" ; obo:VO_0003158 "Rabies Vaccine" ; obo:VO_0003160 "Vaccine for use in all age groups for pre-exposure and post-exposure prophylaxis against rabies." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM133484.pdf" ; obo:VO_0003162 "103931" ; obo:VO_0003198 "1659730" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Imovax Rabies (USA)" ; rdfs:seeAlso "CVX: 18" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003857 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000703 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000064 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/224903", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm101568.htm" ; obo:VO_0003099 "INFANRIX" ; obo:VO_0003158 "Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed" ; obo:VO_0003160 "For active immunization against diphtheria, tetanus, and pertussis as a 5-dose series in infants and children 6 weeks to 7 years of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM124514.pdf" ; obo:VO_0003162 "BL 103647" ; obo:VO_0003198 "224903" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infanrix" ; rdfs:seeAlso "CVX: 20" ; rdfs:subClassOf obo:VO_0000362, obo:VO_0000714, obo:VO_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003199 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003201 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003384 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003455 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000194 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000605 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000065 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://atomicnewsreview.org/2009/10/22/approval-for-the-arepanrix%E2%84%A2-gsk-vaccine-in-canada/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Influenza Virus Vaccine, H5N1 (for National Stockpile)" ; rdfs:label "Influenza Virus Vaccine H5N1 (Sanofi Pasteur Inc)" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_102793 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000066 obo:IAO_0000115 "JE-VAX is a sterile, lyophilized vaccine for subcutaneous use, prepared by inoculating mice intracerebrally with Japanese encephalitis (JE) virus, ‚ÄúNakayama-NIH‚Äù strain." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm179149.htm" ; obo:VO_0003099 "JE-Vax" ; obo:VO_0003158 "Japanese Encephalitis Virus Vaccine Inactivated" ; obo:VO_0003160 "Indicated for Active Immunization against JE for persons one year age and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM123761.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "JE-Vax" ; rdfs:seeAlso "CVX: 39" ; rdfs:subClassOf obo:VO_0000665, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000698 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000067 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/801721", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm172495.htm" ; obo:VO_0003099 "KINRIX" ; obo:VO_0003158 "Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine" ; obo:VO_0003160 "Active immunization against diphtheria, tetanus, pertussis, and poliomyelitis as the fifth dose in the diphtheria, tetanus, and acellular pertussis (DTaP) vaccine series and the fourth dose in the inactivated poliovirus vaccine (IPV) series in children 4 through 6 years of age whose previous DTaP vaccine doses have been with INFANRIX¬Æ and/or PEDIARIX¬Æ for the first three doses and INFANRIX¬Æ for the fourth dose." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM241453.pdf" ; obo:VO_0003162 "BL 125260" ; obo:VO_0003198 "801721" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine", "Trade Name: KINRIX" ; rdfs:label "Kinrix" ; rdfs:seeAlso "CVX: 130" ; rdfs:subClassOf obo:VO_0000742, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003199 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003201 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003384 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003390 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003455 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003835 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003836 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003837 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000068 obo:IAO_0000115 "a bacterial vaccine vector that uses L. moncytogenes as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Listeria monocytogenes vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 1639" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0000069 obo:IAO_0000115 "A Measles-Mumps-Rubella vaccine that is live attenuated and manufactured by Merck & Co, Inc. " ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "MMR II" ; obo:IAO_0000119 "https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm094050.htm" ; obo:VO_0003099 "M-M-R II" ; obo:VO_0003158 "Measles, Mumps, and Rubella Virus Vaccine, Live" ; obo:VO_0003160 "M-M-R II is indicated for simultaneous vaccination against measles, mumps, and rubella in individuals 12 months of age or older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM123789.pdf" ; obo:VO_0003162 "BL 101069" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M-M-R II" ; rdfs:seeAlso "CVX: 03" ; rdfs:subClassOf obo:VO_0000731, obo:VO_0001220, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015054 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015056 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000070 obo:IAO_0000115 "A Measles-Mumps vaccine that is manufactured by Merck and used for human. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "MEASLES + MUMPS (MM-VAX)", "MM-VAX" ; obo:IAO_0000119 "http://novaccine.com/wp-content/uploads/2014/02/mmvax_package_insert.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Measles and Mumps Virus Vaccine, Live", "Trade Name: M-M-Vax" ; rdfs:label "M-M-Vax" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000736, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0000007 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0000074 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000071 obo:IAO_0000115 "Menactra, Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine, is indicated for active immunization to prevent invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y and W-135." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine" ; obo:IAO_0000119 "WEB: http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm176044.htm" ; obo:VO_0003099 "Menactra" ; obo:VO_0003158 "Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine" ; obo:VO_0003160 "Active immunization of individuals 9 months through 55 years of age for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y and W-135." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM131170.pdf" ; obo:VO_0003162 "125089" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine", "Trade Name: Menactra" ; rdfs:label "Menactra" ; rdfs:seeAlso "CVX: 114" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0003441, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001256 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003049 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015063 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015069 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015070 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000072 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm179991.htm" ; obo:VO_0003099 "Menomune-A/C/Y/W-135" ; obo:VO_0003158 "Meningococcal Polysaccharide Vaccine, Groups A, C, Y, W-135 Combined" ; obo:VO_0003160 "For active immunization against invasive meningococcal disease caused by Neisseria meningiditis serogroups A, C, Y, and W-135. Menomune ‚Äì A/C/Y/W-135 vaccine is approved for use in persons 2 years of age and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM308370.pdf" ; obo:VO_0003162 "BL 103926" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Menomune A C Y W135" ; rdfs:seeAlso "CVX: 32" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001256 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004859 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004860 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004886 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004888 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000073 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Rubella Virus Vaccine Live", "Trade Name: Meruvax II" ; rdfs:label "Meruvax II" ; rdfs:seeAlso "CVX: 06" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0010637, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000074 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Mumps Virus Vaccine Live", "Trade Name: Mumpsvax" ; rdfs:label "Mumpsvax" ; rdfs:seeAlso "CVX: 07" ; rdfs:subClassOf obo:VO_0000656, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000075 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pBI/tTA DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000076 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pBISIA DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000077 obo:IAO_0000115 "A Mycobacterium vaccine that protects against Mycobacterium tuberculosis." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "tuberculosis vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycobacterium tuberculosis vaccine" ; rdfs:seeAlso "MeSH: D032581" ; rdfs:subClassOf obo:VO_0000592, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1773 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1773 ] . obo:VO_0000078 obo:IAO_0000116 """Mycobax is a BCG vaccine that is made by Sanofi Pasteur, Ltd. Ref: http://www.biopharma.com/cgi/full6.lasso?Key=412.65916""" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: BCG Vaccine", "Trade Name: Mycobax" ; rdfs:label "Mycobax" ; rdfs:seeAlso "CVX: 19" ; rdfs:subClassOf obo:VO_0000771, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000079 obo:IAO_0000115 "an influenza vaccine that is similar to Fluzone but has high dose. " ; obo:IAO_0000117 "Kallan Roan Oliver He" ; obo:IAO_0000119 "WEB: http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM305079.pdf", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.htm" ; obo:VO_0003158 "Fluzone High-Dose", "Influenza Virus Vaccine" ; obo:VO_0003160 "Fluzone High-Dose is indicated for active immunization of persons 65 years of age and older against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM619541.pdf" ; obo:VO_0003162 "BL 103914" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Influenza Virus Vaccine, Trivalent, Types A and B" ; rdfs:label "Fluzone High-dose" ; rdfs:seeAlso "CVX: 140", "CVX: 141", "CVX: 144" ; rdfs:subClassOf obo:VO_0000047, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000080 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pBK-SFV DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000081 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm181973.htm" ; obo:VO_0003158 "Influenza A (H1N1) 2009 Monovalent Vaccine" ; obo:VO_0003160 "Active immunization of persons 4 years of age and older against influenza disease caused by pandemic (H1N1) 2009 virus." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM182242.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H1N1) 2009 Monovalent Vaccine (Novartis)" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, obo:VO_0003211, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000696 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000082 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/352877", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm146759.htm" ; obo:VO_0003099 "Pediarix" ; obo:VO_0003158 "Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B (Recombinant) and Inactivated Poliovirus Vaccine Combined" ; obo:VO_0003160 "For active immunization against diphtheria, tetanus, pertussis, infection caused by all known subtypes of hepatitis B virus, and poliomyelitis. PEDIARIX is approved for use as a three-dose series in infants born of hepatitis B surface antigen (HBsAg)-negative mothers. PEDIARIX may be given as early as 6 weeks of age through 6 years of age (prior to the 7th birthday)." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM241874.pdf" ; obo:VO_0003162 "BL 103907" ; obo:VO_0003198 "352877" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pediarix" ; rdfs:seeAlso "CVX: 110" ; rdfs:subClassOf obo:VO_0000743, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003150 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003384 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003390 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003455 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003835 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003836 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003837 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000083 obo:IAO_0000115 """PedvaxHIB is a highly purified capsular polysaccharide (polyribosylribitol phosphate or PRP) of Haemophilus influenzae type b (Haemophilus b, Ross strain) that is covalently bound to an outer membrane protein complex (OMPC) of the B11 strain of Neisseria meningitidis serogroup B.""" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm253644.htm" ; obo:VO_0003099 "Liquid PedvaxHIB" ; obo:VO_0003158 "Haemophilus B Conjugate Vaccine (Meningococcal Protein Conjugate)" ; obo:VO_0003160 "Liquid PedvaxHIB is indicated for routine vaccination against invasive disease caused by Haemophilus influenzae type b in infants and children 2 to 71 months of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM253652.pdf" ; obo:VO_0003162 "BL 103237/5285" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PedvaxHIB" ; rdfs:seeAlso "CVX: 49", "PMID:", "PMID: 2791073" ; rdfs:subClassOf obo:VO_0000662, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003049 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003408 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000084 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/674453", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm172502.htm" ; obo:VO_0003099 "Pentacel" ; obo:VO_0003158 "Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) Vaccine" ; obo:VO_0003160 "For active immunization against diphtheria, tetanus, pertussis, poliomyelitis and invasive disease caused by Haemophilus influenzae type b when administered to infants and children 6 weeks through 4 years of age (prior to fifth birthday)." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM109810.pdf" ; obo:VO_0003162 "125145" ; obo:VO_0003198 "674453" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pentacel" ; rdfs:seeAlso "CVX: 120" ; rdfs:subClassOf obo:VO_0000744, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003384 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003390 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003455 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003835 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003836 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003837 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015014 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000085 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Plague Vaccine" ; rdfs:label "Plague Vaccine by Greer Laboratories Inc" ; rdfs:seeAlso "CVX: 23" ; rdfs:subClassOf obo:VO_0000648, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000691 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000086 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pBudCE4.1 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000087 obo:IAO_0000115 "a malaria vaccine that protects against malaria caused by Plasmodium falciparum." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Plasmodium falciparum vaccine" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5833 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5833 ] . obo:VO_0000088 obo:IAO_0000117 "Oliver He, Kallan Roan" ; obo:IAO_0000119 "https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm179996.htm" ; obo:VO_0003099 "Pneumovax 23" ; obo:VO_0003158 "Pneumococcal Vaccine, Polyvalent" ; obo:VO_0003160 "PNEUMOVAX 23 is indicated for active immunization against pneumococcal disease caused by those pneumococcal types included in the vaccine in persons 50 years of age or older and persons greater than or equal to 2 years of age who are at increased risk for pneumococcal disease." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM257088.pdf" ; obo:VO_0003162 "BLA 101094" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Pneumococcal Vaccine, Polyvalent" ; rdfs:label "Pneumovax 23" ; rdfs:seeAlso "CVX: 33" ; rdfs:subClassOf obo:VO_0000424, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000888 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003212 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003217 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003218 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003219 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003220 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003221 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003222 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003223 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003224 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003225 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003226 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003227 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003232 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003246 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003248 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003249 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003250 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003252 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003253 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003254 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003255 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003561 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003959 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000089 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Poliovirus Vaccine Inactivated (Human Diploid Cell)", "Trade Name: Poliovax" ; rdfs:label "Poliovax" ; rdfs:subClassOf obo:VO_0000664, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000090 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm", "https://www.prevnar13.com/" ; obo:VO_0003099 "Prevnar" ; obo:VO_0003158 "Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein)" ; obo:VO_0003160 """- Immunization of infants 2, 4, 6 and 12-15 months of age to prevent invasive pneumococcal disease. - Immunization of infants and toddlers against otitis media caused by vaccine serotypes.""" ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM137038.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein)", "STN: BLA 101094" ; rdfs:label "Prevnar" ; rdfs:seeAlso "CVX: 100", "VIOLIN Vaccine ID: 1114" ; rdfs:subClassOf obo:VO_0000424, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003049 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000091 obo:IAO_0000115 "A Measles-Mumps-Rubella-Vericella vaccine that is live and manufactured by Merck & Co, Inc. " ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "WEB: http://www.merck.com/product/usa/pi_circulars/p/proquad/proquad_pi.pdf", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm188806.htm" ; obo:VO_0003099 "PROQUAD" ; obo:VO_0003158 "Measles, Mumps, Rubella and Varicella Virus Vaccine Live" ; obo:VO_0003160 "For vaccination against measles, mumps, rubella, and varicella in children 12 months to 12 years of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM123793.pdf" ; obo:VO_0003162 "125108" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ProQuad" ; rdfs:seeAlso "CVX: 94" ; rdfs:subClassOf obo:VO_0000737, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003273 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015054 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015056 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000092 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 """WEB: https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm112854.htm""" ; obo:VO_0003099 "Fluzone Intradermal" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003160 "Fluzone Intradermal Quadrivalent indicated for active immunization for use in adults 18 through 64 years of age against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM566500.pdf" ; obo:VO_0003162 "BL 103914" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluzone Intradermal Quadrivalent" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0003143, obo:VO_0003439, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003019 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000093 obo:IAO_0000115 "A vaccine adjuvant that is formed as a mineral salt." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "mineral salt vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, obo:VO_0000850, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000147 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000147 ] . obo:VO_0000094 obo:IAO_0000115 "RabAvert Rabies Vaccine is a sterile, freeze-dried vaccine obtained by growing the fixed-virus strain Flury Low Egg Passage (LEP) in primary cultures of chicken fibroblasts." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf", "http://purl.bioontology.org/ontology/RXNORM/219579", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm133517.htm" ; obo:VO_0003099 "RabAvert" ; obo:VO_0003158 "Rabies Vaccine" ; obo:VO_0003160 "Pre-exposure and post-exposure immunization of children and adults" ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM312931.pdf" ; obo:VO_0003162 "BL 103334" ; obo:VO_0003198 "219579" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RabAvert" ; rdfs:seeAlso "CVX: 18" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003862 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000486 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000696 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000095 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Rabies Vaccine Adsorbed" ; rdfs:label "Rabies Vaccine Adsorbed by BioPort Corp" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000688 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000096 obo:IAO_0000117 "Kallan Roan, Oliver He, SGS" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm247508.htm" ; obo:VO_0003158 "Adenovirus Type 4 and Type 7 Vaccine, Live, Oral" ; obo:VO_0003159 "Barr Labs, Inc." ; obo:VO_0003160 "Indicated for active immunization for the prevention of febrile acute respiratory disease caused by Adenovirus Type 4 and Type 7." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM247515.pdf" ; obo:VO_0003162 "BL 125296/0" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Adenovirus Type 4 and Type 7 Vaccine, Live, Oral" ; rdfs:seeAlso "CVX: 143; UMLS_CUI: C0695130; SNOMEDCT: 442561000" ; rdfs:subClassOf obo:VO_0000037, obo:VO_0000367, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003164 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000097 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/496892", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094063.htm" ; obo:VO_0003099 "RotaTeq" ; obo:VO_0003158 "Rotavirus Vaccine, Live, Oral, Pentavalent" ; obo:VO_0003160 "For prevention of rotavirus gastroenteritis in infants 6 weeks to 32 weeks of age caused by types G1, G2, G3, G4, and G9." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142288.pdf" ; obo:VO_0003162 "BL 125122" ; obo:VO_0003198 "496892" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RotaTeq" ; rdfs:seeAlso "CVX: 116" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000658, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004820 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004822 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004823 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004824 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004825 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000098 obo:IAO_0000115 "a lentivirus vaccine vector that uses a SIV strain as the vector" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "SIV based lentivirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11723" ; rdfs:subClassOf obo:VO_0000359 . obo:VO_0000099 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Pcaggs DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000100 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://academic.oup.com/cid/article/32/1/76/311106" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:comment "T helper type 1 (Th1) lymphocytes secrete secrete interleukin (IL)-2, interferon-γ, and lymphotoxin-α and stimulate type 1 immunity, which is characterized by intense phagocytic activity. https://academic.oup.com/cid/article/32/1/76/311106" ; rdfs:label "vaccine-induced T-helper 1 type immune response" ; rdfs:subClassOf obo:VO_0000135 . obo:VO_0000101 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://academic.oup.com/cid/article/32/1/76/311106" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:comment "Th2 cells secrete IL-4, IL-5, IL-9, IL-10, and IL-13 and stimulate type 2 immunity, which is characterized by high antibody titers. https://academic.oup.com/cid/article/32/1/76/311106" ; rdfs:label "vaccine-induced T-helper 2 type immune response" ; rdfs:subClassOf obo:VO_0000135 . obo:VO_0000102 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Tenivac" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm152800.htm" ; obo:VO_0003099 "TENIVAC" ; obo:VO_0003158 "Tetanus and Diphtheria Toxoids Adsorbed For Adult Use" ; obo:VO_0003160 "Indicated for active immunization for the prevention of tetanus and diphtheria in persons 7 years of age and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM152826.pdf" ; obo:VO_0003162 "103171" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "TENIVAC" ; rdfs:subClassOf obo:VO_0000732, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000103 obo:IAO_0000115 "TICE BCG for intravesical use, is an attenuated, live culture preparation of the Bacillus of Calmette and Guerin (BCG) strain of Mycobacterium bovis." ; obo:IAO_0000117 "Kallan Roan", "Oliver He" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=351", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm134033.htm" ; obo:VO_0001818 "351" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:hasDbXref "CVX:19" ; a owl:Class ; rdfs:label "TICE BCG" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0003053 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000104 obo:IAO_0000115 "Typhim Vi, Typhoid Vi Polysaccharide Vaccine, for intramuscular use, is a sterile solution containing the cell surface Vi polysaccharide extracted from Salmonella enterica serovar Typhi, S typhi Ty2 strain." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/114883", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094072.htm" ; obo:VO_0003099 "Typhim Vi" ; obo:VO_0003158 "Typhoid Vi Polysaccharide Vaccine" ; obo:VO_0003160 "For active immunization against typhoid fever for persons two years of age or older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142811.pdf" ; obo:VO_0003162 "103936" ; obo:VO_0003198 "114883" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "TYPHIM VI" ; rdfs:seeAlso "CVX: 101" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0003443, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003849 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000703 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000105 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "T cell epitope in vaccine" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccine T cell epitope" ; rdfs:subClassOf obo:VO_0000811 . obo:VO_0000106 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced T cell mediated immunity" ; rdfs:subClassOf obo:VO_0000135 . obo:VO_0000107 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "T cell vaccine antigen processing and presentation" ; rdfs:subClassOf obo:VO_0000106 . obo:VO_0000108 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus vaccine" ; rdfs:subClassOf obo:VO_0000025, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_235 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000025 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_235 ] ) ] . obo:VO_0000109 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Tetanus Toxoid Adsorbed" ; rdfs:label "Tetanus Toxoid Adsorbed by Aventis Pasteur Inc" ; rdfs:seeAlso "CVX: 35" ; rdfs:subClassOf obo:VO_0000640, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000110 obo:IAO_0000116 "E. coli Int280a has been found to be a protective antigen. This subunit vaccine uses E. coli Int280a combined with adjuvant. This antigen can be used for development of type-specific EPEC or EHEC vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli O157:H7 intimin vaccine" ; rdfs:seeAlso "PMID: 11500434" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000111 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Tetanus & Diphtheria Toxoids Adsorbed for Adult Use" ; rdfs:label "Tetanus and Diphtheria Toxoids Adsorbed by MA Biologic Lab" ; rdfs:subClassOf obo:VO_0000732, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000693 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000112 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed", "Trade Name: Tripedia" ; rdfs:label "Tripedia" ; rdfs:seeAlso "CVX: 20" ; rdfs:subClassOf obo:VO_0000362, obo:VO_0000367, obo:VO_0000738, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000194 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000113 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094035.htm" ; obo:VO_0003099 "Twinrix" ; obo:VO_0003158 "Hepatitis A Inactivated & Hepatitis B (Recombinant) Vaccine" ; obo:VO_0003160 "Active immunization of persons 18 years of age or older against disease caused by hepatitis A virus and infection by all known subtypes of hepatitis B virus." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM110079.pdf" ; obo:VO_0003162 "BL 103850" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Twinrix" ; rdfs:seeAlso "CVX: 104" ; rdfs:subClassOf obo:VO_0000745, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000114 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCAGGST7 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000115 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced T cell activation" ; rdfs:subClassOf obo:VO_0000008 . obo:VO_0000116 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCBINT DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000117 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCdm7 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000118 obo:IAO_0000115 "A vaccine adjuvant that contains microbial derived material." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "microbial derivative vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0000119 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094073.htm" ; obo:VO_0003158 "Varicella Virus Vaccine Live", "Varivax" ; obo:VO_0003160 "Indicated for active immunization for the prevention of varicella in individuals 12 months of age and older" ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142812.pdf", "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142813.pdf" ; obo:VO_0003162 "BL 103552" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varivax" ; rdfs:seeAlso "CVX: 21" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000419, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000120 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094070.htm" ; obo:VO_0003099 "Vivotif" ; obo:VO_0003158 "Typhoid Vaccine Live Oral Ty21a" ; obo:VO_0003160 "For immunization of adults and children greater than 6 years of age against disease caused by Salmonella typhi." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142807.pdf" ; obo:VO_0003162 "103123" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vivotif (USA)" ; rdfs:seeAlso "CVX: 25" ; rdfs:subClassOf obo:VO_0003353, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000687 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000121 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm180913.htm" ; obo:VO_0003099 "YF-Vax" ; obo:VO_0003158 "Yellow Fever Vaccine" ; obo:VO_0003160 """For active immunization of persons 9 months of age and older who: - Are living in or traveling to endemic areas; - Travelling internationally to countries that require evidence of vaccination from entering travelers or; - Laboratory Personnel who might be expose to virulent yellow fever virus or to concentrated preparations of the yellow fever vaccine strain by direct or indirect contact or by aerosols should by vaccinated.""" ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142831.pdf" ; obo:VO_0003162 "BL 103915" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "YF-Vax" ; rdfs:seeAlso "CVX: 37" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0003134, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003371 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000122 obo:IAO_0000115 "a viral vaccine vector that uses Yellow fever vaccine strain 17D as the vector." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 16755933" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Yellow fever 17D vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11090" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0000123 obo:IAO_0000115 "A viral vaccine that protects against infection with Yellow fever virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow fever virus vaccine" ; rdfs:seeAlso "MeSH: D022341" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11089 ] . obo:VO_0000124 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm136941.htm" ; obo:VO_0003099 "Zostavax" ; obo:VO_0003158 "Zoster Vaccine, Live" ; obo:VO_0003160 "For prevention of herpes zoster (shingles) in individuals 50 years of age and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM132831.pdf", "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM285015.pdf" ; obo:VO_0003162 "125123" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Zostavax" ; rdfs:seeAlso "CVX: 121" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000419, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000125 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed turkey vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9005 ] . obo:VO_0000126 obo:IAO_0000115 "a vaccine organism that is live and attenuated" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "live attenuated vaccine organism" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000506, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ] . obo:VO_0000127 obo:IAO_0000115 "An aluminum vaccine adjuvant that contains aluminum hydroxide." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000118 "alum" ; a owl:Class ; rdfs:label "aluminum hydroxide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000884 . obo:VO_0000128 obo:IAO_0000115 "An aluminum vaccine adjuvant that is aluminum phosphate." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "Adju-Phos®", "Al(PO)4" ; a owl:Class ; rdfs:label "aluminum phosphate vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000884 . obo:VO_0000129 obo:IAO_0000115 "Vaccination frequency is a qualitative term that represents how many times vaccination has occurred." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccination frequency" ; rdfs:subClassOf obo:PATO_0000044 . obo:VO_0000130 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA I/Amp DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000131 obo:IAO_0000115 "A mineral salt vaccine adjuvant composed of calcium phosphate." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "CaHPO4" ; a owl:Class ; rdfs:label "calcium phosphate vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000093 . obo:VO_0000132 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA3 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000133 obo:IAO_0000115 "An emulsion vaccine adjuvant that consists of a water-in-oil emulsion of aqueous antigen in paraffin (mineral) oil of low specific gravity and low viscosity. It is named after Jules T. Freund (1890-1960), Hungarian-born American immunologist. It is a water in oil emulsion." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "Freund's emulsified oil adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0000134 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced T cell proliferation" ; rdfs:subClassOf obo:VO_0000115 . obo:VO_0000135 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced adaptive immune response" ; rdfs:subClassOf obo:VO_0000287 . obo:VO_0000136 obo:IAO_0000115 "a viral vaccine vector that uses an adenovirus as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "adenovirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10508" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0000137 obo:IAO_0000115 "a vaccine role that indicates the vaccine being a combination vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "combination vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000138 obo:IAO_0000115 "A type of 'has vaccine vector' relation that specifies a bacterial vaccine vector" ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has bacterial vaccine vector" ; rdfs:range obo:NCBITaxon_2 ; rdfs:subPropertyOf obo:VO_0000530 . obo:VO_0000139 obo:IAO_0000115 "A Freund's emulsified oil adjuvant that contains inactivated and dried mycobacteria, usually Mycobacterium tuberculosis (the pathogenic agent of tuberculosis)." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "complete Freund's adjuvant" ; rdfs:subClassOf obo:VO_0000133 . obo:VO_0000140 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "agglutinating antibody role" ; rdfs:subClassOf obo:VO_0000148 . obo:VO_0000141 obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "obsolete virulence factor" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000142 obo:IAO_0000115 "A Freund's emulsified oil adjuvant that does not contain the mycobacterial components." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "incomplete Freund's adjuvant" ; rdfs:subClassOf obo:VO_0000133 . obo:VO_0000143 obo:IAO_0000115 "A microbial derivative vaccine adjuvant consisting of cholera toxin (CT) from Vibrio cholerae." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "CT", "cholera toxin" ; a owl:Class ; rdfs:label "cholera toxin vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0000144 obo:IAO_0000115 "a viral vaccine vector that uses an alphavirus as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "alphavirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11019" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0000145 obo:IAO_0000115 "a vaccine component role that inheres in a recombinant vaccine vector as a vaccine component. The combination of a recombinant vaccine vector and a heterogenous protective antigen(s) inserted inside the vector for a recombinant vector vaccine. " ; obo:IAO_0000117 "YH,YL" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "recombinant vaccine vector role" ; rdfs:subClassOf obo:VO_0000617 . obo:VO_0000146 obo:IAO_0000115 "A microbial derivative vaccine adjuvant that is the P40 particulate fraction isolated from Corynebacterium." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:8447157" ; a owl:Class ; rdfs:label "Corynebacterium-derived P40 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0000147 obo:IAO_0000115 "an adjuvant role that inheres in a vaccine component which is added as part of a vaccine and induces enhanced adaptive immune response to the vaccine antigen. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:comment """The Latin \"adjuvans\" means to help, particularly to reach a goal. Adjuvant therapy for cancer is surgery followed by chemotherapy or radiation to help decrease the risk of the cancer recurring (coming back). An adjuvant is a substance that helps and enhances the pharmacological effect of a drug or increases the ability of an antigen to stimulate the immune system.""" ; rdfs:label "vaccine adjuvant role" ; rdfs:subClassOf obo:VO_0000415 . obo:VO_0000148 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "antibody role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0000149 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Aceto Pharma Corp" . obo:VO_0000150 obo:IAO_0000115 "A titer of antibody that shows how much antibody an organism has produced that recognizes a particular epitope, expressed as the greatest dilution ratio (or its reciprocal) that still gives a positive result. ELISA is a common means of determining antibody titers." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Antibody_titer" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "antibody titer" ; rdfs:subClassOf obo:VO_0000555 . obo:VO_0000151 obo:IAO_0000115 "an organismal quality that indicates an organism (e.g., human) is immunized against a disease." ; obo:IAO_0000116 "To assign the state of 'immunized', we will need to do some assay to measure indicators of immunity, e.g., antibody titers in serum samples." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "immunized" ; rdfs:subClassOf obo:PATO_0001995 . obo:VO_0000152 obo:IAO_0000115 "a bacterial vaccine against an infection with F. tularensis." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Francisella tularensis vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_263 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000165 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_263 ] ) ] . obo:VO_0000153 obo:IAO_0000115 "A vaccine preparation that results in the generation of a toxoid vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of toxoid vaccine" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000561 ] . obo:VO_0000154 obo:IAO_0000115 "A Brucella abortus gene that has the name sodC and comes from strain 2308. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment """IMMUNOGENICITY: The SodC protein induces antigen-specific Th1 immune response, as indicated by the specific induction of serum IgG2a, but not IgG1, antibodies and by the secretion of IFN-alpha but not IL-4, by the Cu/Zn SOD-stimulated splenocytes. This gene has been used for vaccine development [PubMed: 10816475][PubMed: 11953393][PubMed: 12933826]. MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replacement exhibited much greater susceptibility to killing by exogenous O(2)(-) than the parental 2308 strain, supporting a role for SodC in protecting this bacterium from O(2)(-) stress. The B abortus sodC mutant was much more sensitive to killing by cultured resident peritoneal macrophages from C57BL6J mice than 2308, and its attenuation in cultured murine macrophages was enhanced when these phagocytes were treated with gamma interferon. The attenuation of the B abortus sodC mutant in both resting and IFN-gamma-activated macrophages was alleviated in the presence of the NADPH oxidase inhibitor apocynin. Consistently, the B abortus sodC mutant also displayed significant attenuation in infected C57BL6J mice compared to the parental strain. These findings suggest that SodC protects B abortus 2308 from the respiratory burst of host macrophages [PubMed: 15845493].""" ; rdfs:label "sodC from B. abortus strain 2308" ; rdfs:seeAlso "NCBI Gene GI: 3827840; NCBITaxon: 234" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000793, obo:VO_0001232, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_359391 ] . obo:VO_0000155 obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "obsolete bacterial gene" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000156 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "viral gene" ; rdfs:subClassOf obo:OGG_0000000002 . obo:VO_0000157 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "HIV gene" ; rdfs:subClassOf obo:VO_0000156 . obo:VO_0000158 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA3.1 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000159 obo:IAO_0000112 "Brucella abortus cattle vaccine RB51 was developed by serial passages of virulent B. abortus strain 2308 in vitro in rifampin agar plates (Reference: PMID: 1908158)." ; obo:IAO_0000115 "A live attenuated vaccine prepraration process that is performed by serial passages in vitro for pathogen attenuation." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of live attenuated vaccine by serial passages in vitro" ; rdfs:subClassOf obo:VO_0000718 . obo:VO_0000160 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm181971.htm" ; obo:VO_0003158 "Influenza A (H1N1) 2009 Monovalent Vaccine" ; obo:VO_0003160 "Active immunization of persons 6 months of age and older against influenza disease caused by pandemic (H1N1) 2009 virus." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM182404.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H1N1) 2009 Monovalent Vaccine (Sanofi Pasteur)" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, obo:VO_0003211, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000161 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "E. coli gene" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Escherichia coli gene" ; rdfs:subClassOf obo:OGG_2000000002 . obo:VO_0000162 obo:IAO_0000115 "a virulence of vaccine organism that shows an avirulent pheontype of the organism as the major component of a vaccine. The avirulence means that an vaccine organism is not virulent and does not cause pathogenic phenotype in a host organism." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccine organism avirulent" ; rdfs:subClassOf obo:PATO_0002146 . obo:VO_0000163 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced gene up-regulation controlling intracellular bacterial replication" ; rdfs:subClassOf obo:VO_0000569 . obo:VO_0000164 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Mycobacterium tuberculosis gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_1773 ] . obo:VO_0000165 obo:IAO_0000115 "A vaccine that targets against a bacterial disease." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bacterial vaccine" ; rdfs:seeAlso "MeSH: D001428" ; rdfs:subClassOf obo:VO_0005504, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2 ] . obo:VO_0000166 obo:IAO_0000115 "a vaccine vector that uses a live bacterium as the vector " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "bacterial vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 2" ; rdfs:subClassOf obo:VO_0000599 . obo:VO_0000167 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA3.1V5HisTOPO/TA DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000168 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Salmonella gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0000169 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Shigella gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_620 ] . obo:VO_0000170 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "protozoan gene" ; rdfs:subClassOf obo:OGG_0000000002 . obo:VO_0000171 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Plasmodium gene" ; rdfs:subClassOf obo:VO_0000170 . obo:VO_0000172 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Plasmodium falciparum gene" ; rdfs:subClassOf obo:VO_0000171 . obo:VO_0000173 obo:IAO_0000115 "a virulence of vaccine organism that shows an attenuated pheontype of the organism as the major component of a vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccine organism live attenuated" ; rdfs:subClassOf obo:PATO_0002146 . obo:VO_0000174 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Leishmania gene" ; rdfs:subClassOf obo:VO_0000170 . obo:VO_0000175 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCEP4 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000176 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced T cell differentiation" ; rdfs:subClassOf obo:VO_0000115 . obo:VO_0000177 obo:IAO_0000115 "A vaccine that prevents or treats cancer. It is produced using the patient's own whole tumor cells as the source of antigens, or using tumor-specific antigens, often recombinantly produced." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000118 "neoplasm vaccine", "tumor vaccine" ; oboInOwl:hasDbXref "MeSH:D019496" ; a owl:Class ; rdfs:label "cancer vaccine" ; rdfs:subClassOf obo:VO_0005503, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0000178 obo:IAO_0000115 "A vaccine preparation that results in the generation of a inactivated vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "inactivated vaccine preparation" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001103 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000315 ] . obo:VO_0000179 obo:IAO_0000115 "a processed material that is output of the vaccine preparation and part of a vaccine." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "cardinal part of vaccine", "vaccine ingredient" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine component" ; rdfs:subClassOf obo:BFO_0000040, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:BFO_0000040 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000001 ] ) ] . obo:VO_0000180 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced cell activation" ; rdfs:subClassOf obo:VO_0000287 . obo:VO_0000181 obo:IAO_0000115 "A microbial derivative vaccine adjuvant made from bacterial lipopolysaccharide (LPS) of gram-negative bacteria." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "LPS vaccine adjuvant" ; a owl:Class ; rdfs:label "lipopolysaccharide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0000182 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced antibacterial agglutination antibody response" ; rdfs:subClassOf obo:VO_0000309 . obo:VO_0000183 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Japanese encephalitis virus gene" ; rdfs:subClassOf obo:VO_0000156 . obo:VO_0000184 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Ebola virus gene" ; rdfs:subClassOf obo:VO_0000156 . obo:VO_0000185 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Influenza virus gene" ; rdfs:subClassOf obo:VO_0000156 . obo:VO_0000186 obo:IAO_0000115 "A vaccine that uses RNA(s) derived from a pathogen organism." ; obo:IAO_0000116 "Using RNA may eliminate the problem of having to tailor a vaccine for each individual patient with their specific immunity. The advantage of RNA is that it can be used for all immunity types and can be taken from a single cell. DNA vaccines need to produce RNA which then prompts the manufacture of proteins. However, RNA vaccine eliminates the step from DNA to RNA." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000118 "mRNA vaccine" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/RNA_vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RNA vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000728 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000728 ] . obo:VO_0000187 obo:IAO_0000115 "A synthetic vaccine adjuvant formulated to correspond to a component found in a water-soluble extract of cell walls of mycobacteria used in complete Freund's adjuvant (CFA)." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "MDP", "muramyl dipeptide" ; obo:IAO_0000119 "PMID:344799" ; a owl:Class ; rdfs:label "muramyl dipeptide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0000188 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Dengue virus gene" ; rdfs:subClassOf obo:VO_0000156 . obo:VO_0000189 obo:IAO_0000115 "A titer measurement of viable bacterial or fungal numbers. Unlike in direct microscopic counts where all cells, dead and living, are counted, CFU measures viable cells. By convenience the results are given as CFU/mL (colony-forming units per milliliter) for water, and CFU/g (colony-forming units per gram) for soil or other porous material." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "CFU" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Colony-forming_unit" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "colony forming unit" ; rdfs:subClassOf obo:VO_0000555 . obo:VO_0000190 obo:IAO_0000115 "An emulsion vaccine adjuvant that contains an organic polymer with some antigenic epitopes which might be shared with other organic polymers acting as immunostimulators." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "squalene" ; a owl:Class ; rdfs:label "squalene vacccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0000191 obo:IAO_0000115 "A synthetic vaccine adjuvant that is an emulsifier called Arlacel A." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "arlacel A" ; obo:IAO_0000119 "PMID:2042393" ; a owl:Class ; rdfs:label "arlacel A vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0000192 obo:IAO_0000115 "A Montanide vaccine adjuvant that is Montanide 103." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000118 "Montanide 103" ; a owl:Class ; rdfs:label "Montanide 103 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001271 . obo:VO_0000193 obo:IAO_0000115 "A microbial derivitive vaccine adjuvant that contains components from killed Bordetella pertussis. The killed B. pertussis has a strong adjuvant effect on the diphtheria and tetanus toxoids in the DPT vaccines." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "Bordetella pertussis component vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0000194 obo:IAO_0000115 "a USA licensed vaccine role that inheres ina vaccine approven to be by the US FDA to be used for humans in the USA. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "USA licensed human vaccine role" ; rdfs:subClassOf obo:VO_0000489, obo:VO_0000812 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000489 obo:VO_0000812 ) ] . obo:VO_0000195 obo:IAO_0000115 "Conjugate vaccine is vaccine that conjugates/links antigens to the molecules that form the outer coat of disease-causing bacteria to promote an immune response." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A conjugate vaccine is created by covalently attaching a poor (polysaccharide organism) antigen to a carrier protein (preferably from the same microorganism), thereby conferring the immunological attributes of the carrier on the attached antigen. --from wikipedia." ; rdfs:label "conjugate vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ] . obo:VO_0000196 obo:IAO_0000115 "A vaccine preparation that results in the generation of a recombinant vector vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of recombinant vector vaccine" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000484 ] . obo:VO_0000197 obo:IAO_0000117 "YH" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0001448 ; a owl:Class ; rdfs:label "obsolete West Nile virus gene" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000198 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "chickenpox virus gene" ; rdfs:subClassOf obo:VO_0000156 . obo:VO_0000199 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Rubella virus gene" ; rdfs:subClassOf obo:VO_0000156 . obo:VO_0000200 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657331" ; obo:VO_0003198 "1657331" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen" ; rdfs:subClassOf obo:VO_0015084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003584 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003616 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003627 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003715 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003721 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003744 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003757 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003763 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003886 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003890 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003910 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003911 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0015080 ] . obo:VO_0000201 obo:IAO_0000116 "Characteristics: Inactivated baculovirus expressed PCV2 ORF2 protein; adjuvanted" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcilis-PCV2" ; rdfs:subClassOf obo:VO_0001524, [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000202 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Hepatitis A virus gene" ; rdfs:subClassOf obo:VO_0000156 . obo:VO_0000203 obo:IAO_0000116 "Characteristics: Inactivated PCD1-2 chimera; adjuvanted" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Suvaxyn PCV2" ; rdfs:subClassOf obo:VO_0001524, [ a owl:Restriction ; owl:hasValue obo:VO_0000205 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000204 obo:IAO_0000116 "Intervet has merged with Schering-Plough Animal Health and become Intervet/Schering-Plough Animal Health™ (YL.)" ; obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Intervet" . obo:VO_0000205 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Fort Dodge" . obo:VO_0000206 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed pig vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ] . obo:VO_0000207 obo:IAO_0000115 "A vaccine contraindication is a contraindication that increases the risks of a vaccination. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "contraindication for vaccination" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "vaccine contraindication" ; rdfs:subClassOf obo:OAE_0000055 . obo:VO_0000208 obo:IAO_0000115 "a vaccine role that is not licensed or in clinical trial; instead, it has been experimently approved to induce protection or treatment effect in vivo in at least an experimental animal model. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine in research role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000209 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pHIS64 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000210 obo:IAO_0000115 "an immune response detection assay that detects specific antiviral antibodies in a test serum. The serum, usually a twofold dilution series, is mixed with a standard number, usually 4 to 8 HA units, of virus and incubated prior to the addition of a standard suspension of erythrocytes. The highest dilution of serum that inhibits hemagglutination is the HI titer of the serum. For example, influenza (AI) viruses agglutinate erythrocytes through the interaction of the virus surface glycoprotein, the hemagglutinin (HA), with receptors on the surface of the erythrocyte. Inhibition of the agglutination reaction by HA subtype-specific antisera is the basis of the hemagglutination-inhibition (HI) assay." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "HI assay" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "hemagglutination-inhibition assay" ; rdfs:subClassOf obo:VO_0000584 . obo:VO_0000211 obo:IAO_0000115 "an organismal quality of a whole organism vaccine where the whole organism is inactivated/killed and lacks the capability of replication. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "vaccine organism killed" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccine organism inactivated" ; rdfs:subClassOf obo:VO_0001139 . obo:VO_0000212 obo:IAO_0000115 "a DNA vaccine plasmid that uses the plasmid labeled pCI." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/nuccore/5870896" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCI DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0001010 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000213 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "hypersensitivity to chicken product" ; rdfs:subClassOf obo:VO_0000207 . obo:VO_0000214 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCI-neo DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000215 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000216 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV-1 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000217 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000026 ; a owl:Class ; rdfs:label "obsolete pCMV4 DNA vaccine plasmid" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000218 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "hypersensitivity to chicken egg" ; rdfs:subClassOf obo:VO_0000213 . obo:VO_0000219 obo:IAO_0000115 "a vaccine component that is used to dissolve vaccine powder into liquid. The vaccine in a powder form has to be reconstituted by mixing vaccine powder with vaccine solvent before administered." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "vaccine diluent", "vaccine liquid diluent" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine solvent" ; rdfs:subClassOf obo:VO_0000179 . obo:VO_0000220 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMVI.UBF3/2 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000221 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV-3FUB DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000222 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV-int DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000223 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV-LacZ DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000224 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "hypersensitivity to antibiotic" ; rdfs:subClassOf obo:VO_0000207 . obo:VO_0000225 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "hypersensitivity to neomycin" ; rdfs:subClassOf obo:VO_0000224 . obo:VO_0000226 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "hypersensitivity to polymyxin" ; rdfs:subClassOf obo:VO_0000224 . obo:VO_0000227 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "reaction to previous vaccination" ; rdfs:subClassOf obo:VO_0000207 . obo:VO_0000228 obo:IAO_0000115 "a vaccine component that contains the solid form of all vaccine components. A vaccine can be reconstituted by mixing vaccine powder with vaccine solvent." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine powder" ; rdfs:subClassOf obo:VO_0000179 . obo:VO_0000229 obo:IAO_0000115 "A vaccine preparation that results in the generation of a bacterial vaccine" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "bacterial vaccine preparation" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000165 ] . obo:VO_0000230 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV-LIC DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000231 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMVLuc DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000232 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCR3 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000233 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "life-threatening reaction to previous vaccination" ; rdfs:subClassOf obo:VO_0000227 . obo:VO_0000234 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCR3.1 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000235 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "life-threatening reaction to previous influenza vaccination" ; rdfs:subClassOf obo:VO_0000233 . obo:VO_0000236 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCR4-TOPO DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000237 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "hypersensitivity to gentamicin" ; rdfs:subClassOf obo:VO_0000224 . obo:VO_0000238 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "dominant epitope in vaccine" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccine dominant epitope" ; rdfs:subClassOf obo:VO_0000811 . obo:VO_0000239 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced down-regulated gene expression" ; rdfs:subClassOf obo:VO_0000286 . obo:VO_0000240 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "hypersensitity to gelatin" ; rdfs:subClassOf obo:VO_0000207 . obo:VO_0000241 obo:IAO_0000115 "A vaccine prepraration process that is performed by heat inactivation of virulent pathogen." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of vaccine using heat inactivation" ; rdfs:subClassOf obo:VO_0000178 . obo:VO_0000242 obo:IAO_0000115 "CFU reduction assay is an assay that measures the reduction of the colony forming units of infected pathogens in vaccine-vaccinated animals compared to nonvaccinated animals." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "CFU reduction assay" ; rdfs:subClassOf obo:OBI_0000070 . obo:VO_0000243 obo:IAO_0000115 "assay of CFU reduction in spleen is a CFU reduction assay that is measured using the extracted spleen as the tissue for isolation of infected pathogens." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "assay of CFU reduction in spleen" ; rdfs:subClassOf obo:VO_0000242 . obo:VO_0000244 obo:IAO_0000116 "Arginine is a conditionally essential amino acid, meaning most of the time it can be manufactured by the human body, and does not need to be obtained directly through the diet. The biosynthetic pathway however does not produce sufficient arginine, and some must still be consumed through diet. Individuals who have poor nutrition or certain physical conditions may be advised to increase their intake of foods containing arginine. Infants are unable to meet their requirements and thus arginine is nutritionally essential for infants." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "hypersensitity to arginine" ; rdfs:subClassOf obo:VO_0000207 . obo:VO_0000245 obo:IAO_0000115 """A physical quality inhering in a bearer by virtue of the bearer being fit to be eaten.""" ; obo:IAO_0000116 """Melanie has submitted this term and its two subclasses to obo: http://sourceforge.net/tracker/?func=detail&aid=2873643&group_id=76834&atid=595654""" ; obo:IAO_0000117 "YH, MC" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "edibility" ; rdfs:subClassOf obo:PATO_0001241 . obo:VO_0000246 obo:IAO_0000115 "A quality of edibility that inheres in a bearer by virtue of the bearer being suitable for oral ingestion as food, drug, or vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:comment "This term may be submitted to PATO." ; rdfs:label "edible" ; rdfs:subClassOf obo:VO_0000245 . obo:VO_0000247 obo:IAO_0000115 """Vaccine efficacy is an efficacy of a vaccine in induction of protective immune response in vivo or protection against infection of a virulent pathogen. Specifically, vaccine efficacy (VE) is the percentage reduction in disease incidence attributable to vaccination, calculated by means of the following equation: VE(%) = (U - V)/U x 100 where U = the incidence in unvaccinated people and V = the incidence in vaccinated people. Ref: Hadler TC, et al. Immunization in developing countries. In: Vaccines. Editors: Plotkin S, et al. 2008. p1542-71.""" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccine efficacy" ; rdfs:subClassOf obo:PATO_0001029 . obo:VO_0000248 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "history of asthma" ; rdfs:subClassOf obo:VO_0000207 . obo:VO_0000249 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced antiviral neutralizing antibody response" ; rdfs:subClassOf obo:VO_0000309 . obo:VO_0000250 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcREV DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000251 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pgp.LAMP-1. This plasmid has a CMV promoter and contains the human lysosomal-associated membrane protein-1 signal sequence." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pgp.LAMP-1 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 19356616" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000252 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pDRVISV1.0 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000253 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pECK DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000254 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pES. This plasmid has a CMV promoter and contains a kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pES DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 19406186" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000255 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "usage of bronchodilator" ; rdfs:subClassOf obo:VO_0000207 . obo:VO_0000256 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pET21a DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000257 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pET-28a DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000258 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pGA DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000259 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pGEX-3X DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000260 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced follicular dendritic cell activation" ; rdfs:subClassOf obo:VO_0000180 . obo:VO_0000261 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "usage of steroid" ; rdfs:subClassOf obo:VO_0000207 . obo:VO_0000262 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pIRES DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000263 obo:IAO_0000115 "sodBFt is a live vaccine strain mutant of Francisella tularensis with reduced Fe-superoxide dismutase gene expression. Ref: PMID: 18692537." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "C57BL/6 mice were vaccinated intranasally (i.n.) with the sodB(Ft) mutant and challenged i.n. with lethal doses of F. tularensis SchuS4. SodB(Ft) vaccinated mice following SchuS4 challenge exhibited significantly reduced bacterial burden in lungs, liver and spleen, regulated production of pro-inflammatory cytokines and less severe histopathological lesions compared to the LVS vaccinated mice. The sodB(Ft) vaccination induced a potent humoral immune response and protection against SchuS4 required both CD4 and CD8 T cells in the vaccinated mice" ; rdfs:label "sodB(Ft)" ; rdfs:seeAlso "PMID: 16923916", "PMID: 18692537" ; rdfs:subClassOf obo:VO_0000152, obo:VO_0000367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000264 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "ProtaTek International, Inc" ; rdfs:seeAlso "www.protatek.com" . obo:VO_0000265 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Arko Laboratories Ltd" ; rdfs:seeAlso "www.arkolabs.com" . obo:VO_0000266 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "fungal disease" ; rdfs:subClassOf obo:DOID_4 . obo:VO_0000267 obo:IAO_0000115 "A vaccine that targets against a fungus infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "fungal vaccine" ; rdfs:seeAlso "MeSH: D005657" ; rdfs:subClassOf obo:VO_0005563, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_4751 ] . obo:VO_0000268 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Newport Laboratories, Inc" ; rdfs:seeAlso "www.newportlabs.com" . obo:VO_0000269 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Texas Agricultural Experiment Station" . obo:VO_0000270 obo:IAO_0000115 "A relation that specifies contraindication of a vaccine." ; obo:IAO_0000116 "This relation may be replaced by has_vaccine_allergen. We need to determine if any vaccine contraindicator is not a vaccine allergen." ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has vaccine contraindication" . obo:VO_0000271 obo:IAO_0000115 "A live attenuated Francisella tularensis vaccine. It is available in American Type Culture Collection with ATCC ID: 29684." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "F. tularensis vaccine LVS" ; rdfs:seeAlso "PMID: 16912944", "PMID: 8757866" ; rdfs:subClassOf obo:VO_0000152, obo:VO_0001217, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000272 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pIRES2 DsRed2 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000273 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced T cell interferon-gamma production" ; rdfs:subClassOf obo:VO_0000593 . obo:VO_0000274 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pING DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000275 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pJW24 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000276 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pJW4303 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000277 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pK0 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000278 obo:IAO_0000115 "vaccine function is a function that inheres in a vaccine that induces protective immune response against a disease. It is realized in the immunization process in the host." ; obo:IAO_0000116 "PERSPN: Oliver He: There has been hot discussion about whether we use 'vaccine function' or 'vaccine role'. Vaccine role may not be the good term to use. Vaccine is designed to be 'vaccine', so it should be vaccine function. One special case is cowpox virus. The cowpox virus can be mixed with some liquid like water and used as a smallpox vaccine. In this case, people often say: the cowpox virus has a 'vaccine role'. However, the cowpox virus vaccine is a processed material of a mix of the virus with water. The virus is a virus, it is not a vaccine per se. Therefore, vaccine role may not be an accurate term." ; obo:IAO_0000117 "YH, MC, XZ, and AR" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "vaccine function" ; rdfs:subClassOf obo:BFO_0000034 ; owl:equivalentClass [ a owl:Class ; owl:unionOf (obo:VO_0000452 obo:VO_0000562 ) ] . obo:VO_0000279 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pK3 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000280 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pMV60 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000281 obo:IAO_0000115 "A type of 'has vaccine vector' that is specifically for viral vaccine vector" ; a owl:ObjectProperty ; rdfs:label "has viral vaccine vector" ; rdfs:subPropertyOf obo:VO_0000530 . obo:VO_0000282 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pMAMneoBlue DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000283 obo:IAO_0000115 "a viral vaccine vector that uses a herpesvirus as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "herpesvirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10292" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0000284 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pMASIA DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000285 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pND DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000286 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced host gene response" ; rdfs:subClassOf obo:VO_0000288 . obo:VO_0000287 obo:IAO_0000115 "Any immune system process that functions in the calibrated response of the host to a vaccine." ; obo:IAO_0000116 "The definition of this term is based on the definition of 'immune response (GO:0006955)' . It is a child term of this GO term." ; obo:IAO_0000117 "Y.H.", "Y.L." ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced host immune response" ; rdfs:subClassOf obo:VO_0000288 . obo:VO_0000288 obo:IAO_0000115 "a processual entity that specifies host response to a vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine-induced host response" ; rdfs:subClassOf obo:BFO_0000015, [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:VO_0000001 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000725 ] ) ] ] . obo:VO_0000289 obo:IAO_0000115 "a process that specifies host response to a vaccine adjuvant." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "host response to vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000290 . obo:VO_0000290 obo:IAO_0000115 "a processual entity that specifies host response to a vaccine component." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "host response to vaccine component" ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0000291 obo:IAO_0000115 "a process that specifies host response to a vaccine antigen." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "host response to vaccine antigen" ; rdfs:subClassOf obo:VO_0000290 . obo:VO_0000292 obo:IAO_0000115 "a process that specifies host response to a vaccine vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "host response to vaccine vaccine vector" ; rdfs:subClassOf obo:VO_0000290 . obo:VO_0000293 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pND2 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000294 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pNGVL DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000295 obo:IAO_0000115 "A viral vaccine that protects against infection with human immunodeficiency virus that causes AIDS." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "AIDS vaccine", "HIV vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "human immunodeficiency virus vaccine" ; rdfs:seeAlso "MeSH: D016915" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] ) ] . obo:VO_0000296 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Brinton Laboratories Inc" . obo:VO_0000297 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pNL3-gal DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000298 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pN4a-gal DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000299 obo:IAO_0000115 "A legal organization that represents an association of people with a specific objective." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Company" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "company" ; rdfs:subClassOf obo:OBI_0000245 . obo:VO_0000300 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis strain VTRM1" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000301 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRc/CMV DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000302 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRc/CMV2 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000303 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. suis VTRS1" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella suis strain VTRS1" ; rdfs:seeAlso "PMID: 17428946" ; rdfs:subClassOf obo:VO_0001136, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000304 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRK DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000305 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRSV DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000306 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRSV0 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000307 obo:IAO_0000115 "KKF24 is a recombinant strain of Francisella novicida U112 with iglC mutation (F. novicida delta-iglC::ermC). PMID: 14680699." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002848" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An iglC mutant is highly attenuated in mice. Inoculated mice were challenged 30 days later with wild type F. tularensis and were highly protected" ; rdfs:label "KKF24" ; rdfs:seeAlso "PMID: 16552035" ; rdfs:subClassOf obo:VO_0000152, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000308 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "F. tularensis vaccine LVS lipopolysaccharide" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "F. tularensis vaccine LVS LPS" ; rdfs:seeAlso "PMID: 10722593" ; rdfs:subClassOf obo:VO_0000152, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000208 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000309 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "immunoglobulin mediated immune response to vaccine" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced antibody mediated immune response" ; rdfs:subClassOf obo:VO_0000012 . obo:VO_0000310 obo:IAO_0000115 "a vaccine additive that stabilizes the vaccine emulsification manufacturing process and makes emulsion of the vaccine easier. " ; obo:IAO_0000117 "YH, YL" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/16337664 " ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Emulsifiers help bind ingredients together and keep them from separating, most commonly with oil and water. An emulsifier is also a surfactant that reduces the surface tension of a liquid and results in an easier, smoother spread. Reference: http://www.wisegeek.org/what-is-polysorbate-80.htm " ; rdfs:label "vaccine emulsifier" ; rdfs:subClassOf obo:VO_0000850, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000179 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003025 ] ) ] . obo:VO_0000311 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis lipopolysaccharide vaccine" ; rdfs:subClassOf obo:VO_0001223, [ a owl:Restriction ; owl:onProperty obo:VO_0000525 ; owl:someValuesFrom obo:CHEBI_16412 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000312 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. melitensis LPS-GBOMP subunit vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis LPS-GBOMP noncovalent complex vaccine" ; rdfs:seeAlso "PMID: 8723881" ; rdfs:subClassOf obo:VO_0001223, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000313 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSC65 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000314 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSG2 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000315 obo:IAO_0000115 "A whole organism vaccine that uses an inativated pathogen organism as its component." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "inactivated organism vaccine", "killed vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "inactivated vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] . obo:VO_0000316 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSG5 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000317 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Psin DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000318 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pTARGET DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000319 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pTH DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000320 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pTHamp DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000321 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus DNA vaccine expressing BCSP31, SOD and L7/L12" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus DNA vaccine encoding BCSP31, SOD and L7/L12" ; rdfs:seeAlso "PMID: 17570767" ; rdfs:subClassOf obo:VO_0001225, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0000154 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000322 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pTR600 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000323 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "recombinant B. abortus L7/L12 vaccine" ; obo:IAO_0000119 "PMID: 8873388" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus conjugate vaccine using L7/L12" ; rdfs:subClassOf obo:VO_0000956, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010928 ] . obo:VO_0000324 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pTVG4 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000325 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis DNA vaccine encoding Omp31" ; rdfs:seeAlso "PMID: 17428946" ; rdfs:subClassOf obo:VO_0001226, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010939 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000326 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pUC18 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000327 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pUC19 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000328 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pV1J DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000329 obo:IAO_0000115 "bacterial vaccine that protect against Mycoplasma hyopneumoniae infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycoplasma hyopneumoniae vaccine" ; rdfs:subClassOf obo:VO_0000604, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2099 ] . obo:VO_0000330 obo:IAO_0000115 "A quality of edibility that inheres in a bearer by virtue of the bearer being not suitable for oral ingestion." ; obo:IAO_0000117 "YH, MC" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "inedible" ; rdfs:subClassOf obo:VO_0000245 . obo:VO_0000331 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVCL(pCXN2-mVIN) DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000332 obo:IAO_0000115 "tertiary vaccination is a vaccination that is performed at the third time in a row." ; obo:IAO_0000117 "YH, Thom Todd" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "tertiary vaccination" ; rdfs:subClassOf obo:VO_0000708, [ a owl:Restriction ; owl:onProperty obo:BFO_0000062 ; owl:someValuesFrom obo:VO_0000903 ] . obo:VO_0000333 obo:IAO_0000115 "Protozoa are a diverse group of unicellular eukaryotic organisms,[1] many of which are motile. Originally, protozoa had been defined as unicellular protists with animal-like behavior, e.g., movement. Protozoa were regarded as the partner group of protists to protophyta, which have plant-like behaviour, e.g., photosynthesis.(http://en.wikipedia.org/wiki/Protozoa)" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "Protozoa" ; rdfs:subClassOf obo:NCBITaxon_2759 . obo:VO_0000334 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVR1012 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000335 obo:IAO_0000115 "A vaccination site that is used for injection of a vaccine. " ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "vaccine injection site" ; rdfs:subClassOf obo:VO_0003247 . obo:VO_0000336 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVR1012x/s DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000337 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pWRG1644 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000338 obo:IAO_0000115 "A B. melitensis vaccine that is recombinant B. melitensis Rev. 1 vaccine with the bp26 deletion. It has similar vaccine efficacy to Rev. 1. Its advantage compared to Rev. 1 is that this feature of bp26 deletion promotes diagnosis. PMID: 17070627." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Brucella CGV26", "CGV26" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis bp26 deletion vaccine" ; rdfs:seeAlso "PMID: 16519974" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_29459 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:VO_0002561 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ] . obo:VO_0000339 obo:IAO_0000115 "A spontaneous mutant of the SCHU S4 strain that protects against virulent F. tularensis infection. PMID: 16299332." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "F. tularensis vaccine FSC043" ; rdfs:seeAlso "PMID: 16299332" ; rdfs:subClassOf obo:VO_0000152, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000340 obo:IAO_0000115 "A route of administration that inject the material(such as vaccines, allergens) directly into a muscle." ; obo:IAO_0000117 "YH,YL" ; obo:IAO_0000118 "intramuscular injection route" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intramuscular route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000341 obo:IAO_0000115 "A rounte of administration that located in nose." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intranasal route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000342 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intranasal route by drop" ; rdfs:subClassOf obo:VO_0000341 . obo:VO_0000343 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intranasal route by spray" ; rdfs:subClassOf obo:VO_0000341 . obo:VO_0000344 obo:IAO_0000115 "A route of administration that located in the peritoneum." ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intraperitoneal route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000345 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis WR201" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000346 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pWRG7077 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000347 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus bacA mutant" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus bacA mutant" ; rdfs:seeAlso "PMID: 17196866" ; rdfs:subClassOf obo:VO_0001134, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000348 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm181975.htm" ; obo:VO_0003158 "Influenza A (H1N1) 2009 Monovalent Vaccine" ; obo:VO_0003160 "Active immunization of persons ages 6 months and older against influenza disease caused by pandemic (H1N1) 2009 virus." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM182401.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H1N1) 2009 Monovalent Vaccine (CSL Limited)" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, obo:VO_0003211, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000689 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000349 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm181970.htm" ; obo:VO_0003158 "Influenza A (H1N1) 2009 Monovalent Vaccine" ; obo:VO_0003160 "Active immunization of individuals 2-49 years of age against influenza disease caused by pandemic (H1N1) 2009 virus." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM182406.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H1N1) 2009 Monovalent Vaccine ( MedImmune LLC)" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0003143, obo:VO_0003211, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003020 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000694 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000350 obo:IAO_0000117 "MC, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Arepanrix" ; rdfs:subClassOf obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000351 obo:IAO_0000115 "A synthetic vaccine adjuvant that is PCPP salt." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Adjumer", "PCPP salt", "polyidi (carboxylatophenoxy) lphosphazene", "polyphosphazene" ; obo:IAO_0000119 "PMID:75551218" ; a owl:Class ; rdfs:label "Adjumer vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0000352 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "Megan Egg is a Salmonella vaccine that that consists of a double gene-deleted S. enterica serovar Typhimurium strain and is formulated fro immunization of pullets. Megan Egg contains the same Megan Vac1 organism but Megan Vac1 is used for younger birds (broilers).", "WEB: http://www.fda.gov/ohrms/dockets/dockets/00n0504/00N-0504_emc-001650-02.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Megan Egg" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000353 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pWRM DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000354 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 16481077" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. ovis microparticle subunit vaccine" ; rdfs:subClassOf obo:VO_0002925, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000355 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pzz DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000356 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pME18100 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000357 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVIVO2 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000358 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Brucella rSurA protein vaccine", "Brucella recombinant SurA protein" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella recombinant SurA protein vaccine" ; rdfs:seeAlso "PMID: 17686554" ; rdfs:subClassOf obo:VO_0001221, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000359 obo:IAO_0000115 "a viral vaccine vector that uses a lentivirus as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "lentivirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11646" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0000360 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA1.1/Amp DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000361 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced leukocyte activation" ; rdfs:subClassOf obo:VO_0000180 . obo:VO_0000362 obo:IAO_0000115 "a licensed human vaccine that is licensed in the USA." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm093833.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "USA licensed human vaccine" ; rdfs:subClassOf obo:VO_0000635, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000194 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000194 ] . obo:VO_0000363 obo:IAO_0000115 "A vaccine that is licensed for commercial use." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed vaccine" ; rdfs:subClassOf obo:VO_0000001, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ] . obo:VO_0000364 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRK7 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000365 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "lipopolysaccharide of pathogen organism as vaccine component" ; rdfs:subClassOf obo:VO_0000000 . obo:VO_0000366 obo:IAO_0000115 "A particulate antigen delivery system that contains particles made up of concentric lipid membranes containing phospholipids and other lipids in a bilayer configuration separated by aqueous compartments. It is a relatively stable but non-covalently-bound complex of saponin adjuvant Quil-A, cholesterol and amphipathic antigen in a molar ratio of approximately 1:1:1. The spectrum of viral capsid antigens and non-viral amphipathic antigens of relevance for human vaccination, incorporated into ISCOMs, comprises influenza, measles, rabies, gp340 from EB-virus, gp120 from HIV, Plasmodium falciparum and Trypanosoma cruzi." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "http://www.vaccination.inoz.com/adjuvants.html" ; a owl:Class ; rdfs:label "liposome-based vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001356 . obo:VO_0000367 obo:IAO_0000115 "A live vaccine that is made from microbes that have been attenuated (weakened) in the laboratory so that they can't cause disease." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "attenuated vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ] . obo:VO_0000368 obo:IAO_0000115 "a vaccine organism that is live" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "live vaccine organism" ; rdfs:subClassOf obo:VO_0000506, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001145 ] . obo:VO_0000369 obo:IAO_0000115 "A 'has vaccine component' relation that specifies the plasmid used for development of a particular DNA vaccine. " ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has DNA vaccine plasmid" ; rdfs:subPropertyOf obo:VO_0000520 . obo:VO_0000370 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live virulent vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000612 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000612 ] . obo:VO_0000371 obo:IAO_0000115 "quaternary vaccination is a vaccination that is performed at the fourth time in a row." ; obo:IAO_0000117 "YH, Thom Todd" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "quaternary vaccination" ; rdfs:subClassOf obo:VO_0000708, [ a owl:Restriction ; owl:onProperty obo:BFO_0000062 ; owl:someValuesFrom obo:VO_0000332 ] . obo:VO_0000372 obo:IAO_0000115 "A vaccine that is used to improve conception." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "profertility vaccine" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0000373 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella recombinant DnaK protein vaccine" ; rdfs:seeAlso "PMID: 17686554" ; rdfs:subClassOf obo:VO_0001221, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000374 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "divalent DNA B. abortus vaccine using L7/L12 and Omp16" ; rdfs:seeAlso "PMID: 16622210" ; rdfs:subClassOf obo:VO_0001225, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000375 obo:IAO_0000112 "'Mycobacterium avium relA mutant vaccine' includes a gene mutation of relA from virulent Mycobacterium avium. " ; obo:IAO_0000115 "A live attenuated vaccine prepraration process that is performed by mutation of a gene(s) from a virulent pathogen." ; obo:IAO_0000117 "YH, YL, ZX" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of gene mutant vaccine" ; rdfs:subClassOf obo:VO_0000718 . obo:VO_0000376 obo:IAO_0000115 "A route of administration that is through the membrane covering the muscles and nerves at the back of the eyeball" ; obo:IAO_0000117 "Y.L." ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "subtenon route" ; rdfs:seeAlso "http://ncim.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20MetaThesaurus&code=CL426248" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000377 obo:IAO_0000115 "An oral route of administration that is underneath the tongue." ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "sublingual route" ; rdfs:seeAlso "http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38300" ; rdfs:subClassOf obo:VO_0000886 . obo:VO_0000378 obo:IAO_0000117 "Y.L." ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intravaginal route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000379 oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "intravaginal vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000378 ] . obo:VO_0000380 oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:comment "YH" ; rdfs:label "subtenon vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000376 ] . obo:VO_0000381 oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "sublingual vaccination" ; rdfs:subClassOf obo:VO_0003021, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000377 ] . obo:VO_0000382 oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "pharyngeal mucosal vaccination" ; rdfs:subClassOf obo:VO_0003021, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000953 ] . obo:VO_0000383 obo:IAO_0000115 "a vaccine-induced T cell interferon-gramm production that results from the addition of a vaccine adjuvant" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced, adjuvant boosted T cell interferon-gramm production" ; rdfs:subClassOf obo:VO_0000273 . obo:VO_0000384 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 """PMID:18472194 """ ; a owl:Class ; rdfs:label "IL-15 plasmid vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001342 . obo:VO_0000385 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus DNA vaccine encoding L7/L12 and P39" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus DNA vaccine encoding L7/L12 and P39" ; rdfs:seeAlso "PMID: 16537031" ; rdfs:subClassOf obo:VO_0001225, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000386 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "attenuated Brucella abortus with deletion of znuA" ; rdfs:seeAlso "PMID: 16790759" ; rdfs:subClassOf obo:VO_0001134, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000387 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "mucosal immune response to vaccine" ; rdfs:subClassOf obo:VO_0000408 . obo:VO_0000388 obo:IAO_0000115 "A microbial derivative vaccine adjuvant that is derived from E. coli heat labile toxin LT." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "E. coli LT toxin derived vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0000389 obo:IAO_0000115 "viral vaccine that is used to protect against Feline panleukopenia virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline panleukopenia virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10786 ] . obo:VO_0000390 obo:IAO_0000115 "Vaccine that used for immunizing birds." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "birds vaccine" ; rdfs:subClassOf obo:VO_0001461, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8825 ] . obo:VO_0000391 obo:IAO_0000115 "bacterial vaccine that is used to protect against Leptospira spp. infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leptospira spp. vaccine" ; rdfs:subClassOf obo:VO_0003553, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000165 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] ) ] . obo:VO_0000392 obo:IAO_0000115 "a Campylobacter bacterial vaccine that is used to protect against Campylobacter fetus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Campylobacter fetus vaccine" ; rdfs:subClassOf obo:VO_0000568, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_196 ] . obo:VO_0000393 obo:IAO_0000115 "bacterial vaccine that is used to protect against Pseudomonas aeruginosa infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudomonas aeruginosa vaccine" ; rdfs:subClassOf obo:VO_0000766, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0000394 obo:IAO_0000115 "a Bordetella bacterial vaccine that is used to protect against Bordetella bronchiseptica infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella bronchiseptica vaccine" ; rdfs:subClassOf obo:VO_0000587, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_518 ] . obo:VO_0000395 obo:IAO_0000117 "YH, YL, ZX" ; obo:IAO_0000118 "a vaccine organism that is inactived/killed", "killed vaccine organism" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "inactivated vaccine organism" ; rdfs:subClassOf obo:VO_0000315, obo:VO_0000506, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] . obo:VO_0000396 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed rabbit vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9986 ] . obo:VO_0000397 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "neutralizing antibody role" ; rdfs:subClassOf obo:VO_0000148 . obo:VO_0000398 obo:IAO_0000112 "A B. melitensis vaccine that is composed of live Brucella melitensis attenuated mutant vjbR::Tn5 (BMEII1116) delivered using alginate microspheres that is coated with a protein of the parasite Fasciola hepatica (vitelline protein B [VpB]). PMID: 18362129." ; obo:IAO_0000115 "A B. melitensis vaccine that is composed of live Brucella melitensis attenuated mutant delivered using a microsphere delivery system." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "The deletion of vjbR gene in Brucella melitensis strain 16M made a live attenuated vaccine and provided significance protection against mice" ; rdfs:label "microencapsulated B. melitensis mutant vaccine" ; rdfs:seeAlso "PMID: 18362129" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000399 obo:IAO_0000115 "A vaccine-induced adjuvant boosted T cell interferon-gramm production that results from the addition of a IL-15 vaccine adjuvant" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 18472194" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced T cell interferon-gramm production boosted by IL-15 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000383 . obo:VO_0000400 obo:IAO_0000115 "a vaccine that contains one vaccine for priming and at least one other vaccine for boosting. " ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "prime-boost vaccine" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0000401 obo:IAO_0000115 "a vaccine that contains one DNA vaccine for priming and at least one other vaccine for boosting. " ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "prime-boost vaccine with DNA vaccine priming" ; rdfs:subClassOf obo:VO_0000400 . obo:VO_0000402 obo:IAO_0000119 "PMID: 12848591" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AIDSVAX" ; rdfs:seeAlso "http://en.wikipedia.org/wiki/AIDSVAX" ; rdfs:subClassOf obo:VO_0000295 . obo:VO_0000403 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "complex of porin and S-LPS from B. abortus strain 2308" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "porin-S-LPS from B. abortus strain 2308" ; rdfs:seeAlso "PMID: 2844673" ; rdfs:subClassOf obo:VO_0001221, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000404 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus RB51WboA" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus RB51WboA" ; rdfs:seeAlso "PMID: 15327798" ; rdfs:subClassOf obo:VO_0001134, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000405 obo:IAO_0000115 """The AIDSVAX that is bicovalent vaccine including two kinds of gp120 protein: MN rgp120/HIV-1 and GNE8 rgp120/HIV-1 (MN and GNE8 are strain names). Resource: ClinicalTrials.gov""" ; obo:IAO_0000116 "link to another well-known study: VAX004", "linkto the clinical trail database by : ClinicalTrials.gov Identifier: NCT00002441" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AIDSVAX B/B" ; rdfs:subClassOf obo:VO_0000402 . obo:VO_0000406 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AIDSVAX B/E" ; rdfs:subClassOf obo:VO_0000402 . obo:VO_0000407 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant O. anthropi 49237SOD" ; rdfs:seeAlso "PMID: 11953393" ; rdfs:subClassOf obo:VO_0000957, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000166 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000408 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "organ or tissue specific immune response to vaccine" ; rdfs:subClassOf obo:VO_0000287 . obo:VO_0000409 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed horse vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9788 ] . obo:VO_0000410 obo:IAO_0000115 "Pandemrix is an influenza vaccine for influenza pandemics, such as the H1N1 2009 flu pandemic colloquially called the swine flu. The vaccine was developed by GlaxoSmithKline and patented in September 2006." ; obo:IAO_0000117 "YL" ; obo:IAO_0000118 "Pandemrix H1N1" ; obo:IAO_0000119 "http://en.wikipedia.org/wiki/Pandemrix" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "ATC code J07BB02", """As well as the active antigen derived from A/California/7/2009 (H1N1), the vaccine contains an immunologic adjuvant AS03 which consists of DL-Œ±-tocopherol (vitamin E), squalene and polysorbate 80. Thiomersal (thimerosal) is added as a preservative. Being manufactured in chicken eggs, it contains trace amounts of egg proteins. Additional important non-medicinal ingredients are formaldehyde, sodium deoxycholate, and sucrose. (http://en.wikipedia.org/wiki/Pandemrix)""" ; rdfs:label "Pandemrix" ; rdfs:subClassOf obo:VO_0000578, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001346 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003036 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000411 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. melitensis Bp26 and trigger factor" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis Bp26 and Tf protein vaccine" ; rdfs:seeAlso "PMID: 17239499" ; rdfs:subClassOf obo:VO_0001223, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000412 obo:IAO_0000115 "A Brucella subunit vaccine that uses recombinant Brucella melitensis 16M P39, a putative periplasmic binding protein. PMID: 11447155." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis P39 recombinant protein vaccine" ; rdfs:seeAlso "PMID: 11447155" ; rdfs:subClassOf obo:VO_0001223, [ a owl:Restriction ; owl:onProperty obo:VO_0000525 ; owl:someValuesFrom obo:VO_0010948 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000413 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "rBLSOmp31" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant chimera BLSOmp31" ; rdfs:seeAlso "PMID: 17442465" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000414 obo:IAO_0000115 "Panvax is an H1N1 unadjuvanted monovalent vaccine." ; obo:IAO_0000117 "MC, YH" ; obo:IAO_0000119 "WEB: http://www.infowars.com/h1n1-panvax-training-powerpoint-received-by-health-care-workers-in-australia/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Panvax" ; rdfs:subClassOf obo:VO_0000578, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000689 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000415 obo:IAO_0000115 "A role inheres in a material entity, that has been added into a vaccine's formulation by the manufacture for a specific purpose. For example: adjuvant to enhance the effect of immunogen, perservatives, stablizers and those materials added for affecting PH and isotonicity." ; obo:IAO_0000117 "YL,YH" ; obo:IAO_0000119 "Page 73, Chapter 6, Vaccine, 5th Edition. EXPERT CONSULT by Plotkin SA., et. al. 2008" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine additive role" ; rdfs:subClassOf obo:VO_0000617 . obo:VO_0000416 obo:IAO_0000115 "A route of administration that is located in the vein" ; obo:IAO_0000117 "YH, Thom Todd" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intravenous route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000417 obo:IAO_0000115 "A vaccine that protects against some protozoan disease." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "parasite vaccine", "parasitic vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "protozoan vaccine" ; rdfs:seeAlso "MeSH: D016052" ; rdfs:subClassOf obo:VO_0005563, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000333 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000333 ] . obo:VO_0000418 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine injection 0.5mL vial" ; obo:IAO_0000119 "WEB: http://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm176044.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Meningococcal Polysaccharide (Serogroups A, C, Y and W-135) Diphtheria Toxoid Conjugate Vaccine injection 0.5mL vial", "Trade Name: Menactra" ; rdfs:label "Menactra injection 0.5mL vial" ; rdfs:seeAlso "SNOMEDCT: 416532007; UMLS_CUI:C1563043" ; rdfs:subClassOf obo:VO_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001256 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003049 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015064 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015066 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015068 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015071 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000419 obo:IAO_0000115 "a Varicella-zoster virus vaccine that is live attenuated." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-zoster virus live vaccine" ; rdfs:seeAlso "SNOMEDCT: 412530002; ULMS_CUI: C0770687" ; rdfs:subClassOf obo:VO_0000669 . obo:VO_0000420 obo:IAO_0000115 "a vaccine component that originates from an organism such as a pathogen or a modified organism." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pathogen organism component in vaccine" ; rdfs:subClassOf obo:VO_0000179 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000179 [ a owl:Class ; owl:unionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:OBI_0100026 ] ) ] ) ] . obo:VO_0000421 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus pcDNA-BLS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus pcDNA-BLS" ; rdfs:subClassOf obo:VO_0001225, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010927 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000422 obo:IAO_0000115 "A cancer vaccine that is used against melanoma, a malignant tumor of melanocytes." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Melanoma" ; oboInOwl:hasDbXref "SNOMEDCT:373869007", "UMLS_CUI:C0796561" ; a owl:Class ; rdfs:label "melanoma vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0000423 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "escheriosome-encapsulated B. abortus L7/L12" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "escheriosome-mediated delivery of B. abortus L7/L12" ; rdfs:seeAlso "PMID: 17931756" ; rdfs:subClassOf obo:VO_0001221, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000424 obo:IAO_0000115 "a pneumococcal vaccine that is formed using polyvalent polysaccharides" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.who.int/vaccines/en/pneumococcus.shtml" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "The most common form of the polyvalent pneumococcal vaccine is called the protein-polysaccharide combinations which is known as conjugate vaccines and contain 7‚Äì11 selected polysaccharides bound to a protein carrier. The protein-polysaccharide combinations are able to induce a T-cell dependent immune response. These vaccines are likely to be protective even in children under two years of age, and may reduce pneumococcal transmission through a herd effect." ; rdfs:label "polyvalent pneumococcal vaccine" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000888 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001254 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000425 obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/10700309" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "a Staphyloccoccus vaccine that is made using engineered toxoid." ; rdfs:label "Staphylococcus toxoid vaccine" ; rdfs:subClassOf obo:VO_0000770 . obo:VO_0000426 obo:IAO_0000115 "period of persistence of vaccine induced immune response is a temporal interval during which a vaccine-induced immune response continuously exists. This term is related to the process 'persistence of vaccine induced immune response'." ; obo:IAO_0000117 "YH, MC" ; oboInOwl:inSubset "temporal region" ; a owl:Class ; rdfs:label "period of persistence of vaccine induced immune response" ; rdfs:subClassOf obo:BFO_0000038 . obo:VO_0000427 obo:IAO_0000115 "A vaccine clinical trial that investigates the safety profile of a vaccine in a small group (10-50) of healthy volunteers." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "phase 1 vaccine trial" ; rdfs:subClassOf obo:VO_0000596 . obo:VO_0000428 obo:IAO_0000115 "A vaccine clinical trial that studies vaccine efficacy with a target population (numbering 50-100). Different dosage levels will also be explored at this stage to determine the optimum dose." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "phase 2 vaccine trial" ; rdfs:subClassOf obo:VO_0000596 . obo:VO_0000429 obo:IAO_0000115 "A vaccine clinical trial that takes the trial to a large-scale safety and efficacy study in a relevant patient population, usually in excess of 3,000." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "phase 3 vaccine trial" ; rdfs:subClassOf obo:VO_0000596 . obo:VO_0000430 obo:IAO_0000115 "The final stage of vaccine clinical evaluation. Phase IV occurs after a vaccine or therapy is licensed and is being used by large numbers of people. These studies are not always required or completed." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "phase 4 vaccine trial" ; rdfs:subClassOf obo:VO_0000596 . obo:VO_0000431 obo:IAO_0000115 "Seven F. tularensis proteins including IglC (rLm/iglC) were expressed in recombinant L. monocytogenes (rLm) vaccines. These 7 F. tularensis proteins are: AcpA, Bfr, DnaK, GroEL, IglC, Pld and KatG from SchuS4 strain." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:hasAlternativeId "VO:0011347" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rLm/iglC" ; rdfs:seeAlso "VIOLIN Vaccine ID: 440" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0000432 obo:IAO_0000115 "A subunit nontypeable H. influenzae vaccine that uses Hap protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "nontypeable H. influenzae Hap Protein Vaccine" ; rdfs:seeAlso "PMID: 15557618" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010916 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000433 obo:IAO_0000115 "a Smallpox virus vaccine that uses vaccinia virus" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Vaccinia" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Vaccinia virus is well known for its role as a vaccine that helped eradicate the smallpox disease, making it the first human disease to be successfully eradicated by science." ; rdfs:label "vaccinia virus vaccine" ; rdfs:subClassOf obo:VO_0000651, obo:VO_0001220, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003052 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000686 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000434 obo:IAO_0000115 "Mixed Bacterial Vaccine (MBV, Coley's Toxins) is a historical, vaguely defined preparation of heat-inactivated Streptococcus pyogenes and Serratia marcescens used as non-specific immunotherapy in the treatment of cancer." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "PubMed:22847809" ; a owl:Class ; rdfs:label "Mixed Bacterial Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0000435 obo:IAO_0000115 "a vaccine component that is composed of a plasmid and used in the generation of a DNA vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "DNA vaccine plasmid vector" ; rdfs:subClassOf obo:VO_0000179 . obo:VO_0000436 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "pCIBLSOmp31" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis DNA vaccine encoding Omp31 boosted with Omp31" ; rdfs:subClassOf obo:VO_0001226, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000437 obo:IAO_0000115 "a bacterial vaccine against Moraxella bovis infection. Moraxella bovis is a Gram-negative, aerobic, oxidase-positive diplococcus that is implicated in infectious bovine keratoconjunctivitis, an eye disease of cattle, also colloquially known as Pink Eye." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Moraxella_bovis" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Moraxella bovis vaccine" ; rdfs:subClassOf obo:VO_0000165 . obo:VO_0000438 obo:IAO_0000115 "a Moraxella bovis vaccine that is prepared using a bacterial bacterin." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Moraxella bovis bacterin vaccine" ; rdfs:seeAlso "UMLS_CUI: C0310839; SNOMEDCT: 39730006" ; rdfs:subClassOf obo:VO_0000437 . obo:VO_0000439 obo:IAO_0000115 "a USA licensed vaccine role that indicates the vaccine is for veterinary uses." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "USDA licensed veterinary vaccine role" ; rdfs:subClassOf obo:VO_0000551, obo:VO_0000812 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000551 obo:VO_0000812 ) ] . obo:VO_0000440 obo:IAO_0000112 "WEB: http://news.prnewswire.com/ViewContent.aspx?ACCT=109&STORY=/www/story/09-15-2009/0005094621&EDATE @2009/10/06", "WEB: http://www.examiner.com/x-7707-Infectious-Disease-Examiner~y2009m9d15-News-Release-H1N1-vaccines-get-FDA-approval-expected-to-be-available-in-4-weeks @2009/10/06. H1N1 vaccines get FDA approval. Food and Drug Administration announced today that it has approved four vaccines against the 2009 H1N1 influenza virus. Obtaining FDA licensure of this vaccine for A (H1N1) pandemic response is a key milestone that will enable Sanofi Pasteur to provide a licensed vaccine to the U.S. government to support pandemic immunization efforts" ; obo:IAO_0000115 "vaccine approval process is a processual entity that involves approval of a vaccine." ; obo:IAO_0000117 "YH, ZX, AR, and MC" ; obo:IAO_0000118 "vaccine product approval process" ; obo:IAO_0000119 "WEB: http://energycommerce.house.gov/images/stories/Documents/PDF/publications/109_health.pdf @2009/10/06. This is the US Health Law which includes a section about vaccine.", "WEB: http://www.hhs.gov/nvpo/factsheets/fs_tableII_doc2.htm @2009/10/06 #Following the FDA's review of a license application, the sponsor and the FDA may present their findings to the FDA's Vaccines and Related Biological Products Advisory Committee (VRBPAC). This non-FDA expert committee (scientists, physicians, biostatisticians, and a consumer representative) provides advice to the Agency regarding the safety and efficacy of the vaccine for the proposed indication." ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine approval process" ; rdfs:subClassOf obo:OBI_0000011, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000363 ] . obo:VO_0000441 obo:IAO_0000115 "vaccine candidate role is the role of a material entity in an investigation, which has not been experimentally or clinically verified to induce a protection or treatment in vivo in a host organism. " ; obo:IAO_0000116 "This role should be a subclass of 'test substance role', which will be mireoted from OBI by OntoFox." ; obo:IAO_0000117 "BP, YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine candidate role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0000442 obo:IAO_0000115 "CFU measurement assay is an assay that measures the colony forming unit (CFU) of a bacterium in a specific location (e.g., spleen of a mouse)." ; obo:IAO_0000117 "YH, MC" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "CFU measurement assay" ; rdfs:subClassOf obo:OBI_0000070, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000189 ] . obo:VO_0000443 obo:IAO_0000115 """A measurement datum that measues the vaccine effectiveness. It is assessed with respect to prevention of the disease against which the vaccine is given. One simple method to estimate vaccine effectiveness is to use routine data on notifications of disease cases in vaccinated and unvaccinatted children and to compare the porportion of cases vaccinated with the vaccine covervage among the same age group in the general population. If p is the proportion vaccinated in the population and c is the proportion of cases reported to be vaccinated, then VE = (p-c)/p(1-c) x 100%.""" ; obo:IAO_0000117 "YH, MC" ; obo:IAO_0000119 "Hadler TC, et al. Immunization in developing countries. In: Vaccines. Editors: Plotkin S, et al. 2008. p1542-71.", "WEB: http://en.wikipedia.org/wiki/Influenza_vaccine" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccine effectiveness rate" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0000444 obo:IAO_0000115 "vaccine licensing is a vaccine approval process that involves in licensing a vaccine." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine licensing" ; rdfs:subClassOf obo:VO_0000440 . obo:VO_0000445 obo:IAO_0000115 "A relation between a disorder and an infectious pathogen." ; obo:IAO_0000116 """The relation 'infection_of' is introduced to represent an infection caused by an infectious pathogen. A pathogen infection is a disorder. Since the number of pathogens is large, there are numerous infections. To make the description of a specific infection simple, the shortcut term 'infection_of' is defined: infection_of X = infection and has_part some (organism X and has_disposition some infectious disposition)""" ; obo:IAO_0000117 "Alan Ruttenburg", "Allen Xiang", "Bjoern Peters", "Melanie Courtot", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "infection_of" . obo:VO_0000446 obo:IAO_0000117 "YH, XZ" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed chicken vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0000447 obo:IAO_0000115 "a viral vaccine vector that uses an poxvirus as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "poxvirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10240" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0000448 obo:IAO_0000115 "a Salmonella vaccine against infection with S. paratyphi, which causes paratyphoid fevers. Paratyphoid fevers are a group of enteric illnesses caused by serotypic strains of the Salmonella genus of bacteria, S. Paratyphi." ; obo:IAO_0000118 "paratyphoid vaccine" ; obo:IAO_0000119 "WED: http://en.wikipedia.org/wiki/Paratyphoid_fever" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella paratyphi vaccine" ; rdfs:subClassOf obo:VO_0000768 . obo:VO_0000449 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.jefferspet.com/%252332moraxella-bovis-bacterin-piliguard-pinkeye-1-trivalent/camid/liv/cp/16435/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Moraxella Bovis Bacterin Piliguard Pinkeye-1 Trivalent" ; rdfs:subClassOf obo:VO_0000438, [ a owl:Restriction ; owl:hasValue obo:VO_0000893 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000450 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Brucella vaccine using nonpathogenic alphaproteobacteria" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NPAP Brucella vaccine" ; rdfs:seeAlso "PMID: 17715332" ; rdfs:subClassOf obo:VO_0000108, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000451 obo:IAO_0000115 "A viral vaccine that protects against infection with Parainfluenza 3 virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parainfluenza 3 virus vaccine" ; rdfs:seeAlso "UMLS_CUI: C0310756; SNOMEDCT: 82867008" ; rdfs:subClassOf obo:VO_0000749 . obo:VO_0000452 obo:IAO_0000115 "preventive vaccine function is a vaccine function realized by the process of vaccination and leading to induction of an adaptive immune response to the antigens in a vaccine, which protects against a specific disorder." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "prophylactic vaccine function" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "preventive vaccine function" ; rdfs:subClassOf obo:VO_0000278, [ a owl:Restriction ; owl:onProperty obo:BFO_0000054 ; owl:someValuesFrom obo:VO_0000002 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000054 ; owl:someValuesFrom obo:VO_0000495 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000054 ; owl:someValuesFrom obo:VO_0000496 ] . obo:VO_0000453 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "prime boost regimen" ; rdfs:subClassOf obo:VO_0000572 . obo:VO_0000454 obo:IAO_0000116 "Colibacillosis, caused by avian pathogenic Escherichia coli (APEC), is a major problem for the poultry industry in the world." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PubMed: http://www.ncbi.nlm.nih.gov/pubmed/16863080", "WEB: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=134" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "APEC vaccine using GST-Iss fusion protein" ; rdfs:subClassOf obo:VO_0001156 . obo:VO_0000455 obo:IAO_0000115 "a vaccine that is used for prevention against a disease." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "prophylactic vaccine" ; rdfs:subClassOf obo:VO_0000001, [ a owl:Restriction ; owl:onProperty obo:RO_0000085 ; owl:someValuesFrom obo:VO_0000452 ] . obo:VO_0000456 obo:IAO_0000115 "Protection efficacy is an efficiency that is associated with protection by a biological product (e.g., vaccine) against a disease." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "protection efficacy" ; rdfs:subClassOf obo:PATO_0001029 . obo:VO_0000457 obo:IAO_0000115 "Protective antigen is an antigen that stimulates protective immunity when used in vivo." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "protective antigen role" ; rdfs:subClassOf obo:OBI_0000237 . obo:VO_0000458 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "E. coli heat-labile enterotoxin B-subunit (LB-T) vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli LB-T vaccine" ; rdfs:seeAlso "PMID: 11500434" ; rdfs:subClassOf obo:VO_0000041, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000459 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli O157:H7 subunit vaccine expressing Esps and Tir" ; rdfs:seeAlso "PMID: 14670317" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010940 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0000460 obo:IAO_0000115 "an influenza virus vaccine against equine influenza viral infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine influenza vaccine" ; rdfs:seeAlso "UMLS_CUI: C0310723; SNOMEDCT: 51393000" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ] . obo:VO_0000461 obo:IAO_0000117 "YH", "YL" ; oboInOwl:hasAlternativeId "VO:0000986" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian influenza vaccine" ; rdfs:seeAlso "an influenza vaccine for avian use" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf ([ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] ) ] . obo:VO_0000462 obo:IAO_0000115 "An object property that specifies a process that is induced by vaccination of a vaccine" ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "induced by vaccination of" . obo:VO_0000463 obo:IAO_0000115 "a bacterial vaccine against infection with Coxiella burnetii which causes Q fever" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Q fever vaccine" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Q_fever" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coxiella burnetii vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_777 ] . obo:VO_0000464 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "protein of pathogen organism as vaccine component" ; rdfs:subClassOf obo:VO_0000000 . obo:VO_0000465 obo:IAO_0000115 "a S. aureus vaccine that uses bacterin as the protective antigen. " ; obo:IAO_0000117 "Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Staphylococcus aureus bacterin vaccine" ; rdfs:seeAlso "UMLS_CUI: C0310856; SNOMEDCT: 52974007" ; rdfs:subClassOf obo:VO_0002502 . obo:VO_0000466 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "soybean-expressed E. coli LTB vaccine" ; rdfs:seeAlso "PMID: 17188785" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010943 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000467 obo:IAO_0000115 "a S. aureus vaccine that uses the bacterial phage lysate as the protective antigen. " ; obo:IAO_0000117 "Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Staphylococcus aureus phage lysate vaccine" ; rdfs:seeAlso "UMLS_CUI: C0311044; SNOMEDCT: 34679007" ; rdfs:subClassOf obo:VO_0002502 . obo:VO_0000468 obo:IAO_0000115 "a Mycoplasma gallisepticum vaccine that uses bacterin as the protective antigen" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycoplasma gallisepticum bacterin vaccine" ; rdfs:seeAlso "UMLS_CUI: C0310841; SNOMEDCT: 38267006" ; rdfs:subClassOf obo:VO_0000949 . obo:VO_0000469 obo:IAO_0000115 "a bacterial vaccine that uses bacterin from a bacterial strain isolated from a herd with a purpose to generate hard-specific vaccine. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://addisonlabs.com/products/autogenous-bacterins.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "autogenous bacterin vaccine" ; rdfs:subClassOf obo:VO_0000165 . obo:VO_0000470 obo:IAO_0000115 "an autogenous bacterin vaccine that is prepared for poultry use. " ; obo:IAO_0000119 "WEB: http://www.hygieialabs.com/autopoultry.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "autogenous poulty bacterin vaccine" ; rdfs:subClassOf obo:VO_0000469 . obo:VO_0000471 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "nontypeable H. influenzae vaccine" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000472 ] . obo:VO_0000472 obo:IAO_0000115 "Nontypeable Haemophilus influenzae (NTHi) is a nonencapsulated Haemophilus influenzae (a gram-negative bacterium). It is the cause of a number of human respiratory tract diseases, such as otitis media, sinusitis, bronchitis, and pneumonia." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "NTHi" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "nontypeable Haemophilus influenzae" ; rdfs:subClassOf obo:NCBITaxon_727 . obo:VO_0000473 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "rLP4/rLP6/UspA2" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "non-typeable H. influenzae rLP4/rLP6 and Moraxella catarrhalis UspA2 protein vaccine" ; rdfs:seeAlso "PMID: 15308371" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010914 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000474 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "killed nontypeable H. influenzae whole-cell vaccine" ; rdfs:seeAlso "PMID: 1859055", "PMID: 1953532", "PMID: 2184330", "PMID: 2867396" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000475 obo:IAO_0000115 "a Rabies virus vaccine against Rabies in animal" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "animal Rabies vaccine" ; rdfs:seeAlso "UMLS_CUI: C0310767; SNOMEDCT: 10495001" ; rdfs:subClassOf obo:VO_0000650 . obo:VO_0000476 obo:IAO_0000115 "A 'has vaccine component' relation that specifies a gene inserted to DNA vaccine plasmid for development of a particular DNA vaccine, and this gene encodes for a protein antigen. " ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has DNA vaccine antigen gene" ; rdfs:subPropertyOf obo:VO_0000520 . obo:VO_0000477 obo:IAO_0000115 "a Rabies virus vaccine against Rabies in human" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "human Rabies vaccine" ; rdfs:seeAlso "UMLS_CUI: C0305066; SNOMEDCT: 3526007" ; rdfs:subClassOf obo:VO_0000650 . obo:VO_0000478 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli vaccine using intimin polypeptide" ; rdfs:seeAlso "PMID: 14688094", "PMID: 17258324" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010944 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0000479 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "nontypeable H. influenzae cell membrane vaccine (CM-Hi)" ; rdfs:seeAlso "PMID: 10353870" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000480 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Nontypeable H. influenzae lipooligosaccharide-tetanus toxoid conjugate vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "nontypeable H. influenzae LOS-TT conjugate vaccine" ; rdfs:seeAlso "PMID: 12706701", "PMID: 9353024" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10150 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000481 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli subunit vaccine using IroN" ; rdfs:seeAlso "PMID: 17145948" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000482 obo:IAO_0000115 "A vaccine preparation process that uses recombinant molecular technology to prepare recombinant protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of recombinant protein vaccine" ; rdfs:subClassOf obo:VO_0000717 . obo:VO_0000483 obo:IAO_0000115 "A subunit vaccine that is made using a part of whole organism as subunit for vaccine development. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "protein subunit vaccine" ; rdfs:subClassOf obo:VO_0000534 . obo:VO_0000484 obo:IAO_0000115 "A vaccine that uses a modified virus or bacterium to deliver genes that code for microbial antigens to cells of the body." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant vector vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000599 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ] . obo:VO_0000485 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli subunit vaccine using CO393" ; rdfs:seeAlso "PMID: 17145948" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010965 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000486 obo:IAO_0000115 "A chicken egg protein allergen where the protein allergen is ovalbumin, the main protein found in egg write, making up 60-65% of the total protein." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Ovalbumin" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "chicken ovalbumin egg protein allergen" ; rdfs:subClassOf obo:VO_0000912 . obo:VO_0000487 obo:IAO_0000115 "a S. typhi vaccine that is live and orally administerred" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "typhoid live oral vaccine" ; rdfs:seeAlso "UMLS_CUI: C0359940; SNOMEDCT: 346696005" ; rdfs:subClassOf obo:VO_0000671 . obo:VO_0000488 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli subunit vaccine using FyuA" ; rdfs:seeAlso "PMID: 14688094", "PMID: 17258324" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0000489 obo:IAO_0000115 "a licensed vaccine role that is bears in a licensed human vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "licensed human vaccine role" ; rdfs:subClassOf obo:VO_0000630 . obo:VO_0000490 obo:IAO_0000115 "immunization is a processual entity that primes or modifies an adaptivie immune response to some antigens." ; obo:IAO_0000117 "YH, XZ, BP" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Immunization" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "immunization" ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0000491 obo:IAO_0000115 "Active immunization is an immunization process that entails the introduction of a foreign molecule into the body, which causes the body itself to generate adaptive immunity against the target." ; obo:IAO_0000117 "YH, XZ" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Immunization" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "active immunization" ; rdfs:subClassOf obo:VO_0000490 . obo:VO_0000492 obo:IAO_0000115 "Passive immunization is an immunization process where pre-synthesized elements of the immune system are transferred to an organism so that the body does not need to produce these elements itself." ; obo:IAO_0000116 "Currently, antibodies can be used for passive immunization. This method of immunization works very quickly. However, it is short lasting. The antibodies are naturally broken down. If there are no B cells to produce more antibodies, they will disappear.", "YH, XZ" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Immunization" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "passive immunization" ; rdfs:subClassOf obo:VO_0000490, [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:VO_0000585 ] . obo:VO_0000493 obo:IAO_0000115 "natural active immunization is an active immunization that occur naturally when a person or animal comes in contact with antigens includeing microbes." ; obo:IAO_0000117 "YH, XZ" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Immunization" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "natural active immunization" ; rdfs:subClassOf obo:VO_0000491 . obo:VO_0000494 obo:IAO_0000115 "artificial active immunization is an active immunization that occurs when a person or animal is vaccinated with a specific vaccine." ; obo:IAO_0000117 "YH, XZ" ; obo:IAO_0000118 "artificial active immunization" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Immunization" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine immunization" ; rdfs:subClassOf obo:VO_0000491, [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:VO_0001274 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:OBI_0100026 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:VO_0000001 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:VO_0000585 ] . obo:VO_0000495 obo:IAO_0000115 "induction of adaptive immune response to antigen is an active immunization process that results in induction of adaptive immune response to some antigens, for example, in a vaccine." ; obo:IAO_0000117 "YH, XZ" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "induction of adaptive immune response to antigen" ; rdfs:subClassOf obo:VO_0000491 . obo:VO_0000496 obo:IAO_0000115 "disorder prevention is a processual entity that prevents a disorder that is the physical basis of a disease." ; obo:IAO_0000117 "YH, XZ" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "disorder prevention" ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0000497 obo:IAO_0000115 "disorder treatment is a processual entity that leads to treat a disorder that is the physical basis of a disease." ; obo:IAO_0000117 "YH, XZ" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "disorder treatment" ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0000498 obo:IAO_0000115 "modification of adaptive immune response to antigen is an active immunization process that results in modification of an adaptive immune response to some antigens, for example, in a therapeutic vaccine." ; obo:IAO_0000117 "YH, XZ" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "modification of adaptive immune response to antigen" ; rdfs:subClassOf obo:VO_0000491 . obo:VO_0000499 obo:IAO_0000117 "YH, XZ" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "preventive infectious disease vaccine function" ; rdfs:subClassOf obo:VO_0000452 . obo:VO_0000500 obo:IAO_0000115 "infection disorder prevention is a process that prevents a disorder that is the physical basis of an infectious disease." ; obo:IAO_0000117 "YH, XZ" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "infection disorder prevention" ; rdfs:subClassOf obo:VO_0000496 . obo:VO_0000501 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli vaccine using verocytotoxin toxoid" ; rdfs:seeAlso "PMID: 17145948" ; rdfs:subClassOf obo:VO_0000963, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000502 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Inactivated ETEC expressing CFA/I and CFA/II" ; rdfs:seeAlso "PMID: 1612730" ; rdfs:subClassOf obo:VO_0000974, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000503 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed sheep vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ] . obo:VO_0000504 obo:IAO_0000115 "a vaccine role that indicates the vaccine being a whole organism vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "whole organism vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000505 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EHEC O157 subunit vaccine using his-tagged N-terminal intimin" ; rdfs:seeAlso "PMID: 1612730" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000506 obo:IAO_0000115 "an organism that is used as part of a vaccine" ; obo:IAO_0000117 "Yongqun He" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "vaccine organism" ; rdfs:subClassOf obo:OBI_0100026, obo:VO_0000001, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000615 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000615 ] ) ] . obo:VO_0000507 obo:IAO_0000115 "a Canada licensed vaccine role that indicates the vaccine is for veterinary uses." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "Canada licensed veterinary vaccine role" ; rdfs:subClassOf obo:VO_0000551, obo:VO_0000864 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000551 obo:VO_0000864 ) ] . obo:VO_0000508 obo:IAO_0000115 "a diphtheria vaccine that uses diphtheria toxoid" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria toxoid vaccine" ; rdfs:subClassOf obo:VO_0000735 . obo:VO_0000509 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "nontypeable H. influenzae P5 peptide MVF/H3 vaccine" ; rdfs:seeAlso "PMID: 10603411" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10114 ] . obo:VO_0000510 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "nontypeable H. influenzae rTbpB vaccine" ; rdfs:seeAlso "PMID: 10225866" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10114 ] . obo:VO_0000511 obo:IAO_0000116 "ACAM2007 is a vaccine candidate expressing CFA/II." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095642/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ETEC vaccine ACAM2007" ; rdfs:subClassOf obo:VO_0000619, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000512 obo:IAO_0000115 "a viral vaccine against a disease caused by a virus belong to Poxviridae. " ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pox vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10240 ] . obo:VO_0000513 obo:IAO_0000115 "a Pox vaccine for Quail pox" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Quail pox vaccine" ; rdfs:seeAlso "UMLS_CUI: C0310765; SNOMEDCT: 10772009" ; rdfs:subClassOf obo:VO_0000512, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_400570 ] . obo:VO_0000514 obo:IAO_0000115 "a Salmonella vaccine against both typhoid caused by S. typhi and paratyphoid caused by S. paratyphi." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "typhoid-paratyphoid vaccine" ; rdfs:seeAlso "NDF-RT: N0000011275; UMLS_CUI: C0041470; SNOMEDCT: 52628005" ; rdfs:subClassOf obo:VO_0000768 . obo:VO_0000515 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "rough phenotype" ; rdfs:subClassOf obo:VO_0000549 . obo:VO_0000516 obo:IAO_0000115 "a protein from human" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "human protein" ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0000517 obo:IAO_0000116 "ACAM2017 was derived from ACAM2007. Genes aroC, ompC, and ompF were deleted, while CS1 and pStrep were added.", "PMID: 17566016" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095642/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ETEC vaccine ACAM2017" ; rdfs:subClassOf obo:VO_0000619, [ a owl:Restriction ; owl:onProperty obo:VO_0000799 ; owl:someValuesFrom obo:VO_0010941 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000518 obo:IAO_0000116 "This DNA vaccine contains the gene fragment encoding AAs 173-764 of PA." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine encoding PA63" ; rdfs:seeAlso "PMID: 9987172" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010872 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000519 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "human ACPP" ; rdfs:seeAlso "GenBank: AC020633; Protein RefSeq: NP_001090 " ; rdfs:subClassOf obo:VO_0000516, obo:VO_0001232, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0000520 obo:IAO_0000115 "An object property that defines a relation between a vaccine and its component" ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; a owl:ObjectProperty ; rdfs:domain obo:VO_0000001 ; rdfs:label "has vaccine component" . obo:VO_0000521 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine encoding PA83 and LF" ; rdfs:seeAlso "PMID: 15342913" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010857 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9986 ] . obo:VO_0000522 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DAAV using PA and PGA" ; rdfs:seeAlso "PMID: 12960361" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010872 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000523 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "smooth phenotype" ; rdfs:subClassOf obo:VO_0000549 . obo:VO_0000524 obo:IAO_0000115 "An object property that specifies a vaccine antigen" ; obo:IAO_0000116 "This relation only works for those vaccine antigen that is physically part of a vaccine preparation. It does not include those antigens that are not part of vaccine. For example, a protein antigen expressed in a DNA vaccine is not a part of vaccine pe ser. In this case, the vaccine expresses the protein, but the gene is part of the vaccine, not the protein. For the case, we can use the relation 'DNA vaccine expresses protein antigen' under the relation 'expresses'. " ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has vaccine antigen" . obo:VO_0000525 obo:IAO_0000115 "A type of 'has vaccine antigen' relation that is specifically for vaccine protective protein antigen used in subunit vaccine development" ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has subunit vaccine antigen" ; rdfs:subPropertyOf obo:VO_0000524 . obo:VO_0000526 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rPA with adjuvant Nanoemulsion" ; rdfs:seeAlso "PMID: 17502384" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000527 obo:IAO_0000115 "A type of 'has vaccine antigen' relation that is specifically for vaccine protective antigen component" ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has vaccine protective antigen" ; rdfs:subPropertyOf obo:VO_0000524 . obo:VO_0000528 obo:IAO_0000116 "Xref: VIOLIN vaccine ID: 223." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis arabinomannan-protein conjugate" ; rdfs:seeAlso "PMID: 12922145" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9986 ] . obo:VO_0000529 obo:IAO_0000115 "A type of 'has vaccine component' relation that is specifically for vaccine adjuvant component" ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has vaccine adjuvant" ; rdfs:subPropertyOf obo:VO_0000520 . obo:VO_0000530 obo:IAO_0000115 "A type of 'has vaccine component' relation that is specifically for vaccine vector component" ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has vaccine vector" ; rdfs:range obo:VO_0000599 ; rdfs:subPropertyOf obo:VO_0000520 . obo:VO_0000531 obo:IAO_0000115 "An object property that specifies a relation between a vaccine and a vaccine allergen" ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has vaccine allergen" . obo:VO_0000532 obo:IAO_0000115 "A route of administration that is loacted in the hypodermis (subcutaneous tissue) region. " ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "subcutaneous route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000533 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "subdominant epitope in vaccine" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccine subdominant epitope" ; rdfs:subClassOf obo:VO_0000811 . obo:VO_0000534 obo:IAO_0000115 "A vaccine that is composed of a purified protein(s) or other antigenic determinant(s) from a disease-causing organism. A subunit vaccine does not include pathogen nucleic acids. The subunits have less risk of causing adverse reactions." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "subunit vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ] . obo:VO_0000535 obo:IAO_0000116 "Xref: VIOLIN vaccineID: 176." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant S. typhimurium secreting M. tuberculosis ESAT-6" ; rdfs:seeAlso "PMID: 11427279" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010919 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000536 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ag85B and ESAT-6 fusion protein" ; rdfs:seeAlso "PMID:" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010919 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000537 obo:IAO_0000115 "An object property that indicates a secretion of a material (e.g., protein) from a vaccine organism." ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:domain obo:VO_0000001 ; rdfs:label "vaccine organism secretes" . obo:VO_0000538 obo:IAO_0000115 "A 'has vaccine component' relation that is specifically used for vaccine preservative" ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has vaccine preservative" ; rdfs:subPropertyOf obo:VO_0000520 . obo:VO_0000539 obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV, VEV and WEV encephalomyelitis-influenza vaccine-tetanus toxoid" ; rdfs:subClassOf obo:VO_0000541, obo:VO_0002422, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0000540 obo:IAO_0000115 "time of survival of live vaccine inside host is a temporal interval during which a live vaccine survives inside a host organism. This entity is related to the process survival of live vaccine inside host." ; obo:IAO_0000117 "YH, MC" ; oboInOwl:inSubset "temporal region" ; a owl:Class ; rdfs:label "time of survival of live vaccine inside host" ; rdfs:subClassOf obo:BFO_0000038 . obo:VO_0000541 obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV, VEE & WEV encephalomyelitis-tetanus toxoid" ; rdfs:subClassOf obo:VO_0001499, obo:VO_0002420, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0002420 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] ) ] . obo:VO_0000542 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV, VEV and WEV encephalomyelitis-rhinopneumonitis-influenza vaccine-tetanus toxoid" ; rdfs:subClassOf obo:VO_0000541, obo:VO_0002428, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0000543 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "attenuated M. bovis strain WAg539" ; rdfs:seeAlso "PMID: 15784584" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010951 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000544 obo:IAO_0000115 "a vaccinee that is a human being" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "human vaccinee" ; rdfs:subClassOf obo:VO_0001374, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000544 ] . obo:VO_0000545 obo:IAO_0000115 "a population of human beings who are vaccinated." ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "human vaccinee population" ; rdfs:subClassOf obo:BFO_0000040, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000544 ] . obo:VO_0000546 obo:IAO_0000115 "a population group that are vaccinated with a specific vaccine" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "vaccinee group" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccinee population" ; rdfs:subClassOf obo:OBI_0000181 . obo:VO_0000547 obo:IAO_0000115 "An object property that specifies a relation between a vaccine and a vaccinate route" ; a owl:ObjectProperty ; rdfs:domain obo:VO_0000001 ; rdfs:label "vaccinated in route" ; rdfs:range obo:VO_0000574 . obo:VO_0000548 oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "human vaccinee population at age 2-17 years old" ; rdfs:subClassOf obo:VO_0000545, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000548 ] . obo:VO_0000549 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "bacterial phenotype" ; rdfs:subClassOf obo:PATO_0001018 . obo:VO_0000550 obo:IAO_0000115 "A vaccine that is used for treatment for a disease." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "therapeutic vaccine" ; rdfs:subClassOf obo:VO_0000001, [ a owl:Restriction ; owl:onProperty obo:RO_0000085 ; owl:someValuesFrom obo:VO_0000562 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000085 ; owl:someValuesFrom obo:VO_0000562 ] . obo:VO_0000551 obo:IAO_0000115 "a licensed vaccine role that is bears in a licensed veterinary vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "licensed veterinary vaccine role" ; rdfs:subClassOf obo:VO_0000630 . obo:VO_0000552 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "attenuated M. bovis strain WAg520" ; rdfs:seeAlso "PMID: 10225931" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000553 obo:IAO_0000115 "An object property that specifies a relation between a vaccine and its vaccinee" ; a owl:ObjectProperty ; rdfs:domain obo:VO_0000001 ; rdfs:label "has vaccinee" . obo:VO_0000554 oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "human vaccinee at age 2-17 years old" ; rdfs:subClassOf obo:VO_0000544, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000554 ] . obo:VO_0000555 obo:IAO_0000115 "A titer (or titre) is a measure of concentration. Titer testing employs serial dilution to obtain approximate quantitative information from an analytical procedure that inherently only evaluates as positive or negative. The titer corresponds to the highest dilution factor that still yields a positive reading; for example, positive readings in the first 8 serial twofold dilutions translate into a titer of 1:256." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB:http://en.wikipedia.org/wiki/Titer" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "titer" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0000556 obo:IAO_0000115 "a vaccine that is designed to immunize against two or more strains of the same microorganism, or against two or more microorganisms." ; obo:IAO_0000117 "NF, YH" ; obo:IAO_0000119 "WEB: http://coastalcarolinaresearch.com/?p=679" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "multivalent vaccine" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0000557 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "attenuated M. bovis strain WAg522" ; rdfs:seeAlso "PMID: 10225931" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000558 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant nontypeable H. influenzae protein P6 with AdDP" ; rdfs:seeAlso "PMID: 15031801" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000559 obo:IAO_0000115 "A synthetic vaccine adjuvant, adamantylamide dipeptide (AdDP) is the desmuramyl analog of MDP." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "AdDP" ; obo:IAO_0000119 "PMID:8375945" ; a owl:Class ; rdfs:label "adamantylamide dipeptide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0000560 obo:IAO_0000115 "A toxin (from Ancient Greek: œÑŒøŒæŒπŒ∫œåŒΩ toxikon) is a poisonous substance produced within living cells or organisms; man-made substances created by artificial processes are thus excluded. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:comment """The term was first used by organic chemist Ludwig Brieger (1849‚Äì1919).[3] For a toxic substance not produced within living organisms, \"toxicant\" and \"toxics\" are also sometimes used.[citation needed]. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their severity, ranging from usually minor and acute (as in a bee sting) to almost immediately deadly (as in botulinum toxin).-- from Wikipedia.""" ; rdfs:label "toxin" ; rdfs:subClassOf obo:CHEBI_23367 . obo:VO_0000561 obo:IAO_0000115 "A vaccine containing a toxoid, used to protect against toxins produced by certain bacteria. A toxoid (also called inactivated toxin) is a processed toxin that has been treated by chemical means, heat, or irradiation and is no longer capable of causing disease." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "toxoid vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ] . obo:VO_0000562 obo:IAO_0000115 "The therapeutic vaccine function is a function realized by the process of vaccination and leading to induction of an adaptive immune response to the antigens in a vaccine, which ameliorates a specific disorder." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "therapeutic vaccine function" ; rdfs:subClassOf obo:VO_0000278, [ a owl:Restriction ; owl:onProperty obo:BFO_0000054 ; owl:someValuesFrom obo:VO_0000002 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000054 ; owl:someValuesFrom obo:VO_0000497 ] . obo:VO_0000563 obo:IAO_0000115 "a combination vaccine that is used against both bacterial and viral infections." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bacterial and viral combination vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000641, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_10239 obo:NCBITaxon_2 ) ] ] . obo:VO_0000564 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002794" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Gu√©rin vaccination" ; rdfs:label "M. tuberculosis secA2 mutant" ; rdfs:seeAlso "PMID: 17671656" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0000799 ; owl:someValuesFrom obo:VO_0010950 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000565 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCG-Ag85A[Tokyo]" ; rdfs:seeAlso "PMID: 17720625" ; rdfs:subClassOf obo:VO_0003130, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010936 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000566 obo:IAO_0000115 "a bacterial vaccine against Vibrio infection" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Vibrio" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vibrio vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_662 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_662 ] . obo:VO_0000567 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA vaccine Rv1806-1807" ; rdfs:seeAlso "PMID: 16520093" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000568 obo:IAO_0000115 "A vaccine that protects against Campylobacter bacterial infectioni." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Campylobacter vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_194 ] . obo:VO_0000569 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced up-regulated gene expression" ; rdfs:subClassOf obo:VO_0000286 . obo:VO_0000570 obo:IAO_0000117 "YL" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Novartis Animal Health US, Inc." . obo:VO_0000571 obo:IAO_0000115 "a viral vaccine vector that uses an AAV virus as the vector." ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "Adeno-associated virus vector" ; obo:IAO_0000119 "PMID: 24702846; PMID: 24568220; PMID: 24660751; PMID: 24849042; PMID: 24742767; PMID: 24827459" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "AAV vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 272636" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0000572 obo:IAO_0000115 "vaccination protocol is the protocol of a vaccination procedure." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "vaccination schedule" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "vaccination protocol" ; rdfs:subClassOf obo:OBI_0000272, [ a owl:Restriction ; owl:onProperty obo:IAO_0000136 ; owl:someValuesFrom obo:VO_0000002 ] . obo:VO_0000573 obo:IAO_0000115 "A vaccine that protects against Chlamydia bacterial infection." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamydia vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_810 ] . obo:VO_0000574 obo:IAO_0000115 "A path that is located in gross anatomical part of an organism (e.g., human) and is used for administering a vaccine, a drug, fluid, poison, or other substance into the body. " ; obo:IAO_0000116 "CDISC has a codelist: Rout of Administration. Desription from CDISC: The course by which a substance was administered in order to reach the site of action in the body. CDISC_SDTM_Route_of_Administration_Terminology" ; obo:IAO_0000117 "YH,YL" ; obo:IAO_0000119 "http://en.wikipedia.org/wiki/Route_of_administration" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "route of administration" ; rdfs:seeAlso "http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38114", "http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C66729" ; rdfs:subClassOf obo:BFO_0000029 . obo:VO_0000575 obo:IAO_0000115 "vaccine candidate is a processed material that is designed to prevent or ameliorate a disorder in a target organism by modulating adaptive immune responses in that organism by administrating the vaccine." ; obo:IAO_0000116 "During our call, we decided not to say vaccine candidate is an output of vaccine preparation, which may be reserved for vaccine alone. -- Aug 4, 2009." ; obo:IAO_0000117 "YH, AR, BP, LC, MC, and ZX" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccine candidate" ; rdfs:subClassOf obo:OBI_0000047, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000441 ] . obo:VO_0000576 obo:IAO_0000115 "vaccine preservative that has thimerosal as part." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "thimerosal vaccine preservative" ; rdfs:subClassOf obo:VO_0000851, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_9546 ] . obo:VO_0000577 obo:IAO_0000115 "Peptide vaccine is a subunit vaccine that uses small peptide(s) as immunoepitopes." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "peptide vaccine" ; rdfs:subClassOf obo:VO_0000534 . obo:VO_0000578 obo:IAO_0000115 "H1N1 Influenza vaccine is an Influenza virus vaccine that is used to vaccinate against H1N1 Influenza subtype vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H1N1 Influenza vaccine" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000642 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ] ) ] . obo:VO_0000579 obo:IAO_0000115 "bacterial vaccine that is used to protect against Haemophilus somnus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus somnus vaccine" ; rdfs:subClassOf obo:VO_0000661, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ] . obo:VO_0000580 obo:IAO_0000115 "A vaccine component that is chemical substance added to vaccine and enhance and direct immune response to protective antigen. Many of vaccine adjuvants cause a range of serious side-effects." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000179 . obo:VO_0000581 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "H. influenzae gene" ; rdfs:subClassOf obo:OGG_2000000002 . obo:VO_0000582 obo:IAO_0000115 "A vaccine regulatory process that is for vaccine producer to apply for vaccine license." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine license application" ; rdfs:subClassOf obo:VO_0000683 . obo:VO_0000583 obo:IAO_0000116 "Encodes for protein P4" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "nontypeable H. influenzae gene hel (encoding P4)" ; rdfs:subClassOf obo:VO_0000581, obo:VO_0001232, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0000584 obo:IAO_0000115 "An assay that is used to detect the immune response of a host to vaccination of a vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "immune response detection assay" ; rdfs:subClassOf obo:OBI_0000070 . obo:VO_0000585 obo:IAO_0000115 "immunization objective is the specification of an objective to achieve immunization." ; obo:IAO_0000117 "YH, XZ" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Immunization" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "immunization objective" ; rdfs:subClassOf obo:IAO_0000005 . obo:VO_0000586 obo:IAO_0000115 "a multivalent vaccine that is designed to immunize against at least one bacterial disease and one viral disease." ; obo:IAO_0000117 "NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "multivalent vaccine against bacterial and viral diseases" ; rdfs:subClassOf obo:VO_0000165, obo:VO_0000556, obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10239 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf ([ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10239 ] [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2 ] ) ] . obo:VO_0000587 obo:IAO_0000115 "a bacterial vaccine against infection of Bordetella bacterial infection" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Bordetella" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella vaccine" ; rdfs:subClassOf obo:VO_0003532, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_517 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000165 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_517 ] ) ] . obo:VO_0000588 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002790" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls" ; rdfs:label "M. tuberculosis phoP mutant SO2" ; rdfs:seeAlso "PMID: 16564606", "PMID: 17084814" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000589 obo:IAO_0000115 "A bacterial vaccine that is used to protect against Aeromonas bacterial infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Aeromonas vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_642 ] . obo:VO_0000590 obo:IAO_0000115 "vaccine preparation is a manufacturing process to produce a vaccine." ; obo:IAO_0000117 "YH, BP" ; obo:IAO_0000118 "vaccine generation", "vaccine production" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine preparation" ; rdfs:subClassOf obo:OBI_0000011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000055 ; owl:someValuesFrom [ a owl:Restriction ; owl:onProperty obo:RO_0000059 ; owl:someValuesFrom obo:VO_0001479 ] ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000001 ] . obo:VO_0000591 obo:IAO_0000115 "An assay that is used to detect if a vaccine protects a host against infection of virulent pathogen after vaccine immunization." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "vaccine challenge experiment" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "vaccine protection assay" ; rdfs:subClassOf obo:OBI_0000070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:OBI_0000712 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000002 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001209 ] . obo:VO_0000592 obo:IAO_0000115 "A bacterial vaccine that protects against Mycobacterium bacterial infection." ; obo:IAO_0000117 "YH, RR" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Mycobacterium" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycobacterium vaccine" ; rdfs:subClassOf obo:VO_0000165 . obo:VO_0000593 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine specific T cell cytokine production" ; rdfs:subClassOf obo:VO_0000106 . obo:VO_0000594 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine specific T cell mediated cytotoxicity" ; rdfs:subClassOf obo:VO_0000106 . obo:VO_0000595 obo:IAO_0000115 "A dose of vaccine specified by the vaccine manufacturer, distributor, or a regulatory agent." ; obo:IAO_0000117 "YH, MC" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccine dose" ; rdfs:subClassOf obo:OBI_0000984 . obo:VO_0000596 obo:IAO_0000115 "A processual entity by which a vaccine is tested clinically for safety and effectiveness. Clinical trials are conducted in phases. Classically, clinical trials unfold in three phases in order to gather data and information about a vaccine and its performance. This will form the basis of a dossier submitted to regulatory authorities by way of an application for licensure. After a vaccine is licensed and is being used by large numbers of people, a Phase IV study may or may not be taken for vaccine clinical evaluation." ; obo:IAO_0000116 """Most vaccines against a pathogen (e.g., HIV) are not tested by vaccinating people and then deliberately exposing them to virulent pathogen (e.g., HIV). This strategy is never for a vaccine against a disease as serious as HIV. The best way to determine if a vaccine is effective is to test it in a randomized, controlled, double-blind clinical trial. This type of trial is often referred to as the gold standard in medical research and provides the strongest evidence for the efficacy of a vaccine.""" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine clinical trial" ; rdfs:subClassOf obo:OBI_0000011, [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:OBI_0100026 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:VO_0000001 ] . obo:VO_0000597 obo:IAO_0000231 obo:IAO_0000226 ; a owl:Class ; rdfs:label "obsolete class" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000598 obo:IAO_0000115 "A vaccine that uses whole organism as its component" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://onlinelibrary.wiley.com/doi/10.1038/npg.els.0000491/full" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "whole organism vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000504 ] . obo:VO_0000599 obo:IAO_0000116 "a vaccine component that uses a microbe (e.g., bacterium, virus, and parasitic organism) as a vector that is inserted with the DNA(s) of a heterologous protective antigen(s) to generate a \"recombinant vector vaccine\". The microorganism used as a vector generally has a stable non or low pathogenic phenotype for the species the vaccine is intended for. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "recombinant vector" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Vaccine", "WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf", "WEB: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2009/09/WC500003856.pdf" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "recombinant vaccine vector" ; rdfs:subClassOf obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000179 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000145 ] ) ] . obo:VO_0000600 obo:IAO_0000115 "an orthopoxvirus vaccine vector that uses vaccinia virus as the vector" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccinia virus vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10245" ; rdfs:subClassOf obo:VO_0001146 . obo:VO_0000601 obo:IAO_0000115 "A bacterial vaccine that protects against Yersinia bacterial infection." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yersinia vaccine" ; rdfs:subClassOf obo:VO_0003533, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_629 ] . obo:VO_0000602 obo:IAO_0000115 "A bacterial vaccine that is used to protect against Edwardsiella bacterial infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Edwardsiella vaccine" ; rdfs:subClassOf obo:VO_0003551, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_635 ] . obo:VO_0000603 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BCG mutant secreting listeriolysin" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0000604 obo:IAO_0000115 "a bacterial vaccine against Mycoplasma bacterial infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycoplasma vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2093 ] . obo:VO_0000605 obo:IAO_0000115 "a Canada licensed vaccine role that indicates the vaccine is used for human" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "Canada licensed human vaccine role" ; rdfs:subClassOf obo:VO_0000489, obo:VO_0000864 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000489 obo:VO_0000864 ) ] . obo:VO_0000606 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "delta ureC hly+ rBCG" ; rdfs:seeAlso "PMID: 16110326" ; rdfs:subClassOf obo:VO_0003130, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0000607 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Intercell Biomedical" . obo:VO_0000608 obo:IAO_0000115 "An 'expresses' relation that specifies a relation between a DNA vaccine and a protein antigen to be expressed by the DNA vaccine. " ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "DNA vaccine expresses protein antigen" ; rdfs:subPropertyOf obo:RO_0002292 . obo:VO_0000609 obo:IAO_0000115 "A vaccine that targets against a viral disease." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "viral vaccine" ; rdfs:seeAlso "MeSH: D014765" ; rdfs:subClassOf obo:VO_0005504, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10239 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10239 ] . obo:VO_0000610 obo:IAO_0000115 "a vaccine vector that uses a virus as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "viral vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10239" ; rdfs:subClassOf obo:VO_0000599 . obo:VO_0000611 obo:IAO_0000115 "bacterial vaccine that is used to protect against Haemophilus parasuis infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus parasuis vaccine" ; rdfs:subClassOf obo:VO_0000661, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_738 ] . obo:VO_0000612 obo:IAO_0000115 "a virulence of vaccine that shows a virulent pheontype of the organism as the major component of a vaccine. The virulent phenotype means that an vaccine organism is virulent and is able to cause a pathogenic phenotype in a host organism." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccine organism virulent" ; rdfs:subClassOf obo:PATO_0002146 . obo:VO_0000613 obo:IAO_0000112 "M' (intended to refer to a male biological sex), 'Male', 'Man', '1' (intended to refer to a male biological sex)" ; obo:IAO_0000115 "A biological sex datum that represents the biological sex of an animal (including human) as being male." ; obo:IAO_0000117 "Paul Fabry, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "male biological sex datum" ; rdfs:subClassOf obo:VO_0001194 . obo:VO_0000614 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Nontypeable H. influenzae protein P6 with cholera toxin" ; rdfs:seeAlso "PMID: 15297063" ; rdfs:subClassOf obo:VO_0000471, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10114 ] . obo:VO_0000615 obo:IAO_0000115 "A role that inheres in a prepared material entity that is designed to induce protection or treatment for a disease or infection. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0000616 obo:IAO_0000115 "Animal model of vaccine research is a role played by some organism (e.g., mouse) that is used for vaccine research." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "animal model of vaccine research" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0000617 obo:IAO_0000115 "A role that inheres in a material entity that becomes an ingredient of a vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine component role" ; rdfs:subClassOf obo:BFO_0000023, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000001 ] ] . obo:VO_0000618 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine antigen role" ; rdfs:subClassOf obo:VO_0000617 . obo:VO_0000619 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli live attenuated vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0000620 obo:IAO_0000115 "bacterial vaccine that is used to protect against Pasteurella multocida infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pasteurella multocida vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ] . obo:VO_0000621 obo:IAO_0000115 "Animal model of vaccine research is a role played by some organism (e.g., mouse) that is used for vaccine research in the laboratory." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "laboratory animal model of vaccine research" ; rdfs:subClassOf obo:VO_0000616 . obo:VO_0000622 obo:IAO_0000115 "a vaccine antigen role that inheres in a vaccine antigen which is capable of inducing protective immunity. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine protective antigen role" ; rdfs:subClassOf obo:VO_0000618 . obo:VO_0000623 obo:IAO_0000115 "a vaccine role that indicates the vaccine being a DNA vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "DNA vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000624 obo:IAO_0000115 "a vaccine role that indicates the vaccine being a subunit vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "subunit vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000625 obo:IAO_0000115 "a vaccine role that indicates the vaccine being a conjugate vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "conjugate vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000626 obo:IAO_0000115 "Survival assessment is an assay that measures the occurence of death events in one or more organisms that are monitored over time." ; obo:IAO_0000116 "Need to point out more specifically that survival/death is measured." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "survival assessment" ; rdfs:subClassOf obo:OBI_0000070, [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom obo:OBI_0100026 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:IAO_0000109 [ a owl:Restriction ; owl:onProperty obo:IAO_0000136 ; owl:someValuesFrom obo:OBI_0100026 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000417 ; owl:someValuesFrom obo:OBI_0000441 ] . obo:VO_0000627 obo:IAO_0000115 "A vaccine used to prevent infection by Haemophilus influenzae type b (Hib) bacteria. The vaccine works by causing your body to produce its own protection (antibodies) against the disease." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Hib polysaccharide vaccine" ; obo:IAO_0000119 "https://www.mayoclinic.org/drugs-supplements/haemophilus-b-polysaccharide-vaccine-intramuscular-route-injection-route/description/drg-20064142" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. influenzae Type b capsular polysaccharide vaccine" ; rdfs:seeAlso "PMID: 335348", "PMID: 6387614" ; rdfs:subClassOf obo:VO_0000662, obo:VO_0001255, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] . obo:VO_0000628 obo:IAO_0000115 "An E. coli vaccine that uses subunit antigen type." ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli subunit vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0000629 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis recombinant vaccine using PA domain 4" ; rdfs:seeAlso "PMID: 11854261", "PMID: 15935874" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010872 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000630 obo:IAO_0000115 "licensed vaccine role is a regulation-assigned role that indicates that a vaccine obtains official approval for commercial production and selling on the market." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "licensed vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000631 obo:IAO_0000115 "vaccine in clinical trial role is a regulation-assigned role that inheres in a vaccine that is currently in clinical trial." ; obo:IAO_0000116 "In medical research, clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine in clinical trial role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000632 obo:IAO_0000115 "Vaccine induced immue response mediated hrough a body fluid" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced humoral immune response" ; rdfs:subClassOf obo:VO_0000287 . obo:VO_0000633 obo:IAO_0000115 "A B. melitensis vaccine that is recombinant B. melitensis Rev. 1 vaccine with the p39 gene deletion." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. melitensis Rev. 1 P39 deletion mutant" ; obo:IAO_0000119 "PMID: 9784574" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis Rev. 1 with P39 deletion" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000634 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "intravenous vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000416 ] . obo:VO_0000635 obo:IAO_0000115 "a licensed vaccine with license for human use." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed human vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000489 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000489 ] . obo:VO_0000636 obo:IAO_0000115 "a vaccine role that indicates the vaccine being a recombinant vector vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "recombinant vector vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000637 obo:IAO_0000115 "bacterial vaccine that is used to protect against Flavobacterium columnare infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Flavobacterium columnare vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_996 ] . obo:VO_0000638 obo:IAO_0000112 "\"A vaccinates B\" means that the vaccine A is used for vaccinating the host B (e.g., human)." ; obo:IAO_0000115 "A relation between a vaccine instance and an organism type such that if the vaccine instance is given to an instance of the organism by the process vaccination, then it changes the organism's disposition to have an immune response against a disease." ; obo:IAO_0000117 "YH, AR, ZX, MC" ; a owl:ObjectProperty ; rdfs:label "obsolete vaccinates" ; owl:deprecated true . obo:VO_0000639 obo:IAO_0000115 "A bacterial vaccine that protects against infection with Clostridium spp." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Clostridium" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Clostridium vaccine" ; rdfs:subClassOf obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] . obo:VO_0000640 obo:IAO_0000115 "a Clostridium vaccine that protects against infection with Clostridium tetani that causes tenanus." ; obo:IAO_0000117 "Oliver He, Kallan Roan" ; obo:IAO_0000118 "Tetanus toxoid vaccine", "tetanus vaccine" ; obo:IAO_0000119 "https://vaccine-safety-training.org/tetanus-vaccine-example.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Clostridium tetani vaccine" ; rdfs:subClassOf obo:VO_0000561, obo:VO_0000639, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1513 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1513 ] . obo:VO_0000641 obo:IAO_0000115 """Combination vaccine is a vaccine that induces protection against multiple infectious diseases or several different serotypes of the same organism. The anitgens contained in combination vaccines are either formulated together by the manufacturer or physically mixed by a health care provider just prior to administration. Both approaches require licensure. Ref: Baylor NW and Midthum K. Regulation and testing of vaccines. In: Vaccines (Editors: Plotkin S, Orenstein W, and Offit P). 2008. p1624.""" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "combo vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "combination vaccine" ; rdfs:seeAlso "MeSH: D017778" ; rdfs:subClassOf obo:VO_0000001, [ a owl:Restriction ; owl:minQualifiedCardinality "2"^^xsd:nonNegativeInteger ; owl:onClass obo:OBI_0100026 ; owl:onProperty obo:VO_0001243 ] . obo:VO_0000642 obo:IAO_0000115 "A viral vaccine that protects against infection with influenza virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Influenza vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment """There is no single 'influenza virus' in NCBI_Taxon. We usually use: ('unidentified influenza virus' or 'Influenzavirus A' or 'Influenzavirus B' or 'Influenzavirus C') However, even this may not be comprehensive. """ ; rdfs:label "Influenza virus vaccine" ; rdfs:seeAlso "MeSH: D007252; UMLS_CUI: C0021403; SNOMEDCT: 46233009" ; rdfs:subClassOf obo:VO_0000609 . obo:VO_0000643 obo:IAO_0000115 "a vaccine with license that is used for cattle." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed cattle vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0000644 obo:IAO_0000115 "A viral vaccine that protects against infection with Hepatitis B virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Hepatitis_B_vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B virus vaccine" ; rdfs:seeAlso "MeSH: D017325" ; rdfs:subClassOf obo:VO_0003540, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] ) ] . obo:VO_0000645 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed fish vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_7898 ] . obo:VO_0000646 obo:IAO_0000115 "A viral vaccine that protects against infection with Hepatitis A virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A virus vaccine" ; rdfs:seeAlso "MeSH: D022362" ; rdfs:subClassOf obo:VO_0003548, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ] . obo:VO_0000647 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed goat vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9925 ] . obo:VO_0000648 obo:IAO_0000115 "A bacteria vaccine that prevents against Yersinia pestis infection that causes plague." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Plague vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yersinia pestis vaccine" ; rdfs:seeAlso "MeSH: D010931; SNOMEDCT: 11866009; UMLS_CUI:C0032066" ; rdfs:subClassOf obo:VO_0000601, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0000649 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed dog vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9611 ] . obo:VO_0000650 obo:IAO_0000115 "A viral vaccine that protects against infection with Rabies virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies virus vaccine" ; rdfs:seeAlso "MeSH: D011819; SNOMEDCT: 333606008; UMLS_CUI:C0034496" ; rdfs:subClassOf obo:VO_0003545, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] ) ] . obo:VO_0000651 obo:IAO_0000115 "A viral vaccine that protects against infection with Smallpox virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Smallpox virus vaccine" ; rdfs:seeAlso "MeSH: D012900" ; rdfs:subClassOf obo:VO_0000512, obo:VO_0003539, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0000652 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed cat vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9682 ] . obo:VO_0000653 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed ferret vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9669 ] . obo:VO_0000654 obo:IAO_0000115 "A viral vaccine that protects against infection with Measles virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Measles vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles virus vaccine" ; rdfs:seeAlso "MeSH: D008458" ; rdfs:subClassOf obo:VO_0003543, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11234 ] . obo:VO_0000655 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed deer vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9850 ] . obo:VO_0000656 obo:IAO_0000115 "A viral vaccine that protects against infection with Mumps virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mumps virus vaccine" ; rdfs:seeAlso "MeSH: D009108" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560602 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560602 ] ) ] . obo:VO_0000657 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed bird vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8825 ] . obo:VO_0000658 obo:IAO_0000115 "A viral vaccine that protects against infection with Rotavirus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rotavirus vaccine" ; rdfs:seeAlso "MeSH: D022243; UMLS_CUI: C0597418; SNOMEDCT: 116077000" ; rdfs:subClassOf obo:VO_0003542, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] ) ] . obo:VO_0000659 obo:IAO_0000116 "In most cases HibTITER was administered concomitantly with other vaccines including DTP, DTaP, hepatitis B vaccine, IPV, OPV, pneumococcal 7-valent conjugate vaccine, MMR, and/or meningococcal group C conjugate vaccine (not licensed in the US)." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIBTITER" ; rdfs:seeAlso "PMID:", "PMID: 2057256", "PMID: 9353019" ; rdfs:subClassOf obo:VO_0000662, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000660 obo:IAO_0000116 "Ref: http://www.rxlist.com/prohibit-drug.htm" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ProHIBiT" ; rdfs:seeAlso "PMID: 2057256" ; rdfs:subClassOf obo:VO_0000662, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000661 obo:IAO_0000115 "A bacterial vaccine that protects against infection with Haemophilus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Haemophilus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus vaccine" ; rdfs:seeAlso "MeSH: D018073" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_724 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000165 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_724 ] ) ] . obo:VO_0000662 obo:IAO_0000115 "A vaccine that protects against Haemophilus influenzae type b infection." ; obo:IAO_0000117 "Oliver He, Hector Guzman-Orozco" ; obo:IAO_0000118 "Haemophilus b vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae serotype b vaccine" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0012185 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] ) ] . obo:VO_0000663 obo:IAO_0000115 "A live attenuated Shigella flexneri 2a vaccine that carries deletions of the plasmid-borne virulence gene icsA (mediating intra- and intercellular spread) and the chromosomal locus iuc (encoding aerobactin). " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 10377124" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SC602" ; rdfs:seeAlso "PMID: 10377124" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000664 obo:IAO_0000115 "A viral vaccine that protects against infection with Poliovirus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Poliovirus vaccine" ; rdfs:seeAlso "MeSH: D023321" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:NCBITaxon_12080 obo:NCBITaxon_12083 obo:NCBITaxon_12086 ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:NCBITaxon_12080 obo:NCBITaxon_12083 obo:NCBITaxon_12086 ) ] ] . obo:VO_0000665 obo:IAO_0000115 "A viral vaccine that protects against infection with Japanese encephalitis virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Japanese encephalitis vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus vaccine" ; rdfs:seeAlso "MeSH: D022321" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11072 ] . obo:VO_0000666 obo:IAO_0000116 "CVD 1208 is derived from wild type Shigella flexneri 2a strain 2457T and has defined deletions in four genes: (1) the guaBA chromosomal operon that encodes two enzymes (inositol 5'-monophosphate dehydrogenase and guanosine 5'synthase) essential for de novo purine biosynthesis; (2) set, a locus in a chromosomal pathogenicity island that encodes Shigella enterotoxin (ShET); (3) Pic, an autotransporter mucinase encoded on the opposite strand from set; and (4) sen, an invasiveness plasmid gene encoding ShET. PMID: 15499528" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVD 1208" ; rdfs:subClassOf obo:VO_0000680, obo:VO_0001217, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] . obo:VO_0000667 obo:IAO_0000115 "a vaccine against human papillomavirus infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "human papillomavirus vaccine" ; rdfs:seeAlso "UMLS_CUI: C1512511; SNOMEDCT: 424519000" ; rdfs:subClassOf obo:VO_0000748, obo:VO_0003538, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0000668 obo:IAO_0000116 "CVD 1208S is the same thing as CVD 1208, but CVD 1208S was prepared using animal-free media. PMID: 17938573." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVD 1208S" ; rdfs:seeAlso "PMID: 17938573" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000669 obo:IAO_0000115 "a Herpesvirus vaccine that is used against Varicella-zoster virus infection." ; obo:IAO_0000117 "Oliver He, Kallan Roan" ; obo:IAO_0000118 "Varicella vaccine", "chickenpox and shingles virus vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-zoster virus vaccine" ; rdfs:seeAlso "UMLS_CUI: C0078048; SNOMEDCT: 108729007" ; rdfs:subClassOf obo:VO_0000727, obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10335 ] . obo:VO_0000670 obo:IAO_0000116 "This vaccine is an aro-D mutant derivative of EcSf2a-1. PMID: 1587589." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EcSf2a-2" ; rdfs:seeAlso "PMID: 1587589" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000671 obo:IAO_0000115 "a Salmonella vaccine against typhoid fever (or called typoid), caused by Salmonella enterica enterica, serovar Typhi. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "typhoid vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella typhi vaccine" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90370 ] . obo:VO_0000672 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "heat-killed virulent Shigella flexneri 2a" ; rdfs:seeAlso "PMID: 10102148" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9986 ] . obo:VO_0000673 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shigella Sfl 124 vaccine" ; rdfs:seeAlso "PMID: 1937767" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000674 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant SFL124-27 expressing S. dysenteriae type 1 O antigen" ; rdfs:seeAlso "PMID: 9169740" ; rdfs:subClassOf obo:VO_0000681, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000675 obo:IAO_0000115 "a Streptococcal vaccine that is used against S. pneumoniae infection, which causes pneumococcal diseases. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "pneumococcal vaccine" ; obo:IAO_0000119 "WEB: http://www.who.int/vaccines/en/pneumococcus.shtml" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae vaccine" ; rdfs:subClassOf obo:VO_0000772, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0000676 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002919" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "S. dysenteriae 1 strain WRSd1" ; rdfs:seeAlso "PMID: 12010984" ; rdfs:subClassOf obo:VO_0000681, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ] . obo:VO_0000677 obo:IAO_0000115 "A live attenuated Shigella flexneri 2a vaccine with specific deletion mutations in virG, sen, set, and guaBA." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. flexneri 2a strain CVD 1207" ; rdfs:seeAlso "PMID: 10678904" ; rdfs:subClassOf obo:VO_0000680, obo:VO_0001217, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000678 obo:IAO_0000115 "A stable attenuated Shigella sonnei strain with virG mutation. PMID: 9712824." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002921", "VO:0002932", "VO:0002933" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei", "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "Shigella sonnei virG mutant vaccine" ; rdfs:seeAlso "PMID: 11895966", "PMID: 9712824" ; rdfs:subClassOf obo:VO_0000679, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000679 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shigella sonnei vaccine" ; rdfs:subClassOf obo:VO_0000769, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_624 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_624 ] . obo:VO_0000680 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shigella flexneri vaccine" ; rdfs:subClassOf obo:VO_0000769, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_623 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_623 ] . obo:VO_0000681 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shigella dysenteriae vaccine" ; rdfs:subClassOf obo:VO_0000769, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_622 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_622 ] . obo:VO_0000682 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. flexneri 2a LPS vaccine complexed with N. meningitidis proteosomes" ; rdfs:seeAlso "PMID: 8500877" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000683 obo:IAO_0000115 "A processual entity that regulates vaccine-related processes, such as vaccine trial, vaccine license application." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine regulation" ; rdfs:subClassOf obo:OBI_0000011 . obo:VO_0000684 obo:IAO_0000115 "A processual entity of transporting vaccine from one place to another place." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine transportation" ; rdfs:subClassOf obo:OBI_0000011 . obo:VO_0000685 obo:IAO_0000115 "a recombinant vector vaccine role that inheres in a bacterium that carries a vaccine antigen for development of a particular vaccine " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "recombinant bacterial vector vaccine role" ; rdfs:subClassOf obo:VO_0000636 . obo:VO_0000686 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Acambis, Inc" . obo:VO_0000687 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Berna Biotech, Ltd" . obo:VO_0000688 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "BioPort Corp" . obo:VO_0000689 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "CSL Limited" . obo:VO_0000690 obo:IAO_0000115 "A British multinational pharmaceutical company headquartered in Brentford, England" ; obo:IAO_0000117 "Oliver He, Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/GlaxoSmithKline" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "GlaxoSmithKline plc" . obo:VO_0000691 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Greer Laboratories Inc" . obo:VO_0000693 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Massachusetts Public Health Biologic Lab" . obo:VO_0000694 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "MedImmune Vaccines, Inc" . obo:VO_0000695 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Merck Sharp & Dohme Corp."@en ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Merck & Co., Inc." . obo:VO_0000696 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Novartis Vaccines and Diagnostics" . obo:VO_0000697 obo:IAO_0000116 """100 Rodolphe Street Building 1300 Durham, NC 27712""" ; obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Organon Teknika Corp LLC" . obo:VO_0000698 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Research Foundation for Microbial Diseases of Osaka University" . obo:VO_0000699 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Sanofi Pasteur Limited" . obo:VO_0000700 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Sanofi Pasteur, Inc" . obo:VO_0000701 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Wyeth Pharmaceuticals Inc" . obo:VO_0000702 obo:IAO_0000115 "a recombinant vector vaccine role that inheres in a virus that carries a vaccine antigen for development of a particular vaccine " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "recombinant viral vector vaccine role" ; rdfs:subClassOf obo:VO_0000636 . obo:VO_0000703 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Sanofi Pasteur, SA" . obo:VO_0000704 obo:IAO_0000115 "a vaccine residual that is from antibiotics used during the manufacture process." ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "antibiotics vaccine residual" ; rdfs:subClassOf obo:VO_0000854 . obo:VO_0000705 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "vaccine specific antibody test" ; rdfs:subClassOf obo:VO_0000584 . obo:VO_0000706 obo:IAO_0000115 "A vaccine regulation process for vaccine clinical trials." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine trial regulation" ; rdfs:subClassOf obo:VO_0000683 . obo:VO_0000707 obo:IAO_0000115 "A vaccination process that occurs at the first time to a host organization in a specified period." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "prime vaccination" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "primary vaccination" ; rdfs:subClassOf obo:VO_0000002 . obo:VO_0000708 obo:IAO_0000115 "A vaccination process that occurs after the primer vaccination with a purpose to boost host immune response to vaccine antigen." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "boost vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000062 ; owl:someValuesFrom obo:VO_0000707 ] . obo:VO_0000709 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella melitensis vaccine" ; rdfs:subClassOf obo:VO_0000025, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29459 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000025 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29459 ] ) ] . obo:VO_0000710 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Brucella melitensis Rev 1", "Brucella melitensis Rev. 1" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis strain Rev. 1" ; rdfs:seeAlso "PMID: 13416171" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000799 ; owl:someValuesFrom obo:VO_0010963 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9925 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9935 ] . obo:VO_0000711 obo:IAO_0000115 "has_vaccine_allegen is a relation that specifies an allegen to a vaccine." ; obo:IAO_0000117 "YH" ; a owl:ObjectProperty ; rdfs:label "obsolete has_vaccine_allergen" ; owl:deprecated true . obo:VO_0000712 obo:IAO_0000115 "a viral vaccine that is inactivated" ; obo:IAO_0000118 "killed viral vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "inactivated viral vaccine" ; rdfs:subClassOf obo:VO_0000315, obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ) ] . obo:VO_0000713 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "vaccine allergen disposition" ; rdfs:subClassOf obo:BFO_0000016 . obo:VO_0000714 obo:IAO_0000115 "a licensed human vaccine that is licensed in Canada" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canada licensed human vaccine" ; rdfs:subClassOf obo:VO_0000635, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000605 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000605 ] . obo:VO_0000715 obo:IAO_0000115 "A vaccine preparation that results in the generation of a DNA vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of DNA vaccine" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000032 ] . obo:VO_0000716 obo:IAO_0000115 "A vaccine preparation that results in the generation of a conjugate vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of conjugate vaccine" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000195 ] . obo:VO_0000717 obo:IAO_0000115 "A vaccine preparation that results in the generation of a subunit vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "subunit vaccine preparation" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000534 ] . obo:VO_0000718 obo:IAO_0000115 "A vaccine preparation that results in the generation of a live attenuated vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "live attenuated vaccine preparation" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000367 ] . obo:VO_0000719 obo:IAO_0000115 "A vaccine preparation that results in the generation of a RNA vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of RNA vaccine" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000186 ] . obo:VO_0000720 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus strain RB51SOD" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus strain RB51SOD" ; rdfs:seeAlso "PMID: 10816475" ; rdfs:subClassOf obo:VO_0001134, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0000154 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000721 obo:IAO_0000115 "a Brucella vaccine against infection wtih B. suis" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella suis vaccine" ; rdfs:subClassOf obo:VO_0000025, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29461 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000025 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29461 ] ) ] . obo:VO_0000722 obo:IAO_0000115 "An orally administrable brucellosis vaccine that was was developed in China. It is effective for oral vaccination of sheep, goats, cattle and pigsPMID: 3541425." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Brucella suis S2" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella suis strain 2" ; rdfs:subClassOf obo:VO_0001136, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ] . obo:VO_0000723 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus strain 45/20" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus strain 45/20" ; rdfs:seeAlso "PMID: 8236802" ; rdfs:subClassOf obo:VO_0001134, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ] . obo:VO_0000724 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cytomegalovirus vaccine" ; rdfs:subClassOf obo:VO_0000727 . obo:VO_0000725 obo:IAO_0000115 "A viral vaccine that protects against infection with Dengue virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Dengue vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus vaccine" ; rdfs:seeAlso "MeSH: D053059" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] ) ] . obo:VO_0000726 obo:IAO_0000115 "A viral vaccine that protects against infection with Ebola virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Ebola vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus vaccine" ; rdfs:seeAlso "MeSH: D046129" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0000727 obo:IAO_0000115 "A viral vaccine that protects against infection with Herpesvirus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpesvirus vaccine" ; rdfs:seeAlso "MeSH: D022283" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10292 ] . obo:VO_0000728 obo:IAO_0000115 "a vaccine role that indicates the vaccine being a RNA vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "RNA vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000729 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus vaccine" ; rdfs:subClassOf obo:VO_0000727 . obo:VO_0000730 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek disease vaccine" ; rdfs:subClassOf obo:VO_0000727 . obo:VO_0000731 obo:IAO_0000115 "A Measles-Mumps vaccine that also protects against infection with Rubella virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "MMR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "MMR is usually live attenuated. " ; rdfs:label "Measles-Mumps-Rubella vaccine" ; rdfs:subClassOf obo:VO_0000736, obo:VO_0010637, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11041 ] . obo:VO_0000732 obo:IAO_0000115 "A Corynebacterium diphtheriae vaccine that also protect against infection with Clostridium tetani." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus vaccine" ; rdfs:subClassOf obo:VO_0000640, obo:VO_0000735, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1513 ] . obo:VO_0000733 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVD 1204(pGA1-CS2)" ; rdfs:seeAlso "PMID: 11292735" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000734 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVD 1204(pGA1-CS3)" ; rdfs:seeAlso "PMID: 11292735" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000735 obo:IAO_0000115 "A bacterial vaccine that protects against infection with Corynebacterium diphtheriae that causes Diphtheria." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "diphtheria vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Corynebacterium diphtheriae vaccine" ; rdfs:subClassOf obo:VO_0003534, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1717 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1717 ] . obo:VO_0000736 obo:IAO_0000115 "A Measles virus vaccine that also protects against infection with Mumps virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles-Mumps vaccine" ; rdfs:subClassOf obo:VO_0000654, obo:VO_0000656, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560602 ] . obo:VO_0000737 obo:IAO_0000115 "A Measles-Mumps-Rubella vaccine that also protects against Varicella." ; obo:IAO_0000117 "Oliver He, Kallan Roan" ; obo:IAO_0000119 "https://www.cdc.gov/vaccines/hcp/vis/vis-statements/mmrv.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles-Mumps-Rubella-Varicella vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000731, obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10335 ] . obo:VO_0000738 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "DTP vaccine", "DTaP vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Pertussis vaccine" ; rdfs:seeAlso "UMLS_CUI: C0012559; SNOMEDCT: 421245007" ; rdfs:subClassOf obo:VO_0000732, obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] . obo:VO_0000739 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shigella ribosome-based Vaccine (SRB)" ; rdfs:seeAlso "PMID: 17507120" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000740 obo:IAO_0000115 "A malaria vaccine that comprises recombinant Plasmodium falciparum (P. falciparum) blood-stage proteins MSP1, MSP2 and RESA, formulated with the adjuvant Montanide ISA 720. PMID: 14604568." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum vaccine Combination B" ; rdfs:seeAlso "PMID: 14604568" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010959 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000741 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "Haemophilus influenzae serotype b" ; rdfs:subClassOf obo:NCBITaxon_727 . obo:VO_0000742 obo:IAO_0000115 "A vaccine that protects against diphtheria, tetanus, pertussis, and poliovirus." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTaP/IPV vaccine", "diphtheria and tetanus toxoids and acellular pertussis adsorbed and inactivated poliovirus vaccine" ; obo:IAO_0000119 "https://www.nhsinform.scot/healthy-living/immunisation/vaccines/the-4-in-1-vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus vaccine" ; rdfs:subClassOf obo:VO_0000765, obo:VO_0000943, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] . obo:VO_0000743 obo:IAO_0000115 "A vaccine used to prevent infections of diphtheria, tetanus (lockjaw), pertussis (whooping cough), hepatitis B, and poliovirus." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTaP/IPV/HepB vaccine" ; obo:IAO_0000119 "https://www.hendricks.org/HealthLibrary/default.aspx?sid=1&pTitle=%2CDrug&ContentTypeID=26&ContentID=2783&alpha=D&AdditionalTitle=Diphtheria+Toxoid%2C+Tetanus+Toxoid%2C+Acellular+Pertussis+Vaccine%2C+DTaP%3B+Hepatitis+B+Vaccine%2C+Recombinant%3B+Inactivated+Poliovirus+Vaccine%2C+IPV" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine" ; rdfs:subClassOf obo:VO_0000644, obo:VO_0000712, obo:VO_0000742, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000145 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0000744 obo:IAO_0000115 "A vaccine that protects against, Diphtheria, Tetanus, Pertussis (whooping cough), Polio, and Haemophilus influenzae type b." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTaP/IPV/Hib vaccine" ; obo:IAO_0000119 "https://www.healthlinkbc.ca/healthlinkbc-files/dtap-ipv-hib-vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine" ; rdfs:subClassOf obo:VO_0000662, obo:VO_0000742, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] . obo:VO_0000745 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A&B vaccine" ; rdfs:subClassOf obo:VO_0000644, obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ] . obo:VO_0000746 obo:IAO_0000115 "a viral vaccine against Hepatitis B virus and at the same time against bacterial H. influenzae serotype b." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus b and Hepatitis B vaccine" ; rdfs:subClassOf obo:VO_0000644, obo:VO_0000662, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000644 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] ) ] . obo:VO_0000747 obo:IAO_0000115 "A vaccine that contains DNA and modified vaccinia virus Ankara (MVA) encoding thrombospondin-related adhesion protein (TRAP) with a multiple-epitope string ME (ME-TRAP). This vaccine is used with a prime-boost regime by DNA priming and MVA boosting. PMID: 16988273." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA and MVA encoding ME-TRAP" ; rdfs:seeAlso "PMID: 16988273" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010920 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000748 obo:IAO_0000115 "A viral vaccine that protects against infection with Papillomavirus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Papillomavirus vaccine" ; rdfs:seeAlso "MeSH: D053918" ; rdfs:subClassOf obo:VO_0000609 . obo:VO_0000749 obo:IAO_0000115 "A viral vaccine that protects against infection with Parainfluenza virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "parainfluenza vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parainfluenza virus vaccine" ; rdfs:seeAlso "MeSH: D022241" ; rdfs:subClassOf obo:VO_0000609 . obo:VO_0000750 obo:IAO_0000115 "A viral vaccine that protects against infection with Pseudorabies virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "pseudorabies vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies virus vaccine" ; rdfs:seeAlso "MeSH: D022421" ; rdfs:subClassOf obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0000751 obo:IAO_0000115 "A viral vaccine that prevents against infection with Simian immunodeficiency virus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "SAIDS vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Simian immunodeficiency virus vaccine" ; rdfs:seeAlso "MeSH: D018449" ; rdfs:subClassOf obo:VO_0000609 . obo:VO_0000752 obo:IAO_0000115 "A viral vaccine that protects against West Nile virus infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "West Nile virus vaccine" ; rdfs:seeAlso "MeSH: D053060" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] ) ] . obo:VO_0000753 obo:IAO_0000115 "A viral vaccine that prevents infection with Respiratory syncytial virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Respiratory syncytial virus vaccine" ; rdfs:seeAlso "MeSH: D022261" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12814 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12814 ] ) ] . obo:VO_0000754 obo:IAO_0000115 "A vaccine that is used in conjunction with diagnostic tests to differentiate vaccinated animals from carrier animals. It can be a subunit or a gene-deleted vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "marker vaccine" ; rdfs:seeAlso "MeSH: D022581" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0000755 obo:IAO_0000115 "A vaccine that is edible and derived from an edible plant. The transgenic plant is used as recombinant protein production system. The edible plant tissue functions as an oral vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "edible vaccine" ; rdfs:seeAlso "MeSH: D022462" ; rdfs:subClassOf obo:VO_0000001, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000246 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000246 ] ) ] . obo:VO_0000756 obo:IAO_0000115 "acellular vaccine is a subunit vaccine that is produced by using only the antigenic part of the disease causing organism. It often requires a \"booster\" every few years to maintain their effectiveness. MeSH term: D20.215.894.860.900." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "acellular vaccine" ; rdfs:subClassOf obo:VO_0000534 . obo:VO_0000757 obo:IAO_0000115 "A particulate antigen delivery system that consists of an assembly of antigens in multimeric form and presents an antigen to induce specific immunologic responses. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines. MeSH term: D20.215.894.860.449." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000118 "ISCOM", "The immunostimulating complex" ; a owl:Class ; rdfs:label "ISCOM vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001356 . obo:VO_0000758 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Plasmodium vivax vaccine" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5855 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5855 ] . obo:VO_0000759 obo:IAO_0000115 "A vaccine that is used to prevent conception." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "antifertility vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "contraceptive vaccine" ; rdfs:seeAlso "MeSH: D022642" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0000760 obo:IAO_0000115 "A vaccine that prevents or treats Alzheimer disease." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Alzheimer vaccine" ; rdfs:seeAlso "MeSH: D023582" ; rdfs:subClassOf obo:VO_0002813 . obo:VO_0000761 obo:IAO_0000115 "Plasmodium vaccine is a vaccine that prevents against Plasmodium species causing malaria. It is made from antigens arising from any of the four strains of Plasmodium which cause malaria in humans, or from P. berghei which causes malaria in rodents." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Plasmodium vaccine", "malarial Vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "malaria vaccine" ; rdfs:seeAlso "MeSH: D017780" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0000762 obo:IAO_0000115 "a protozoan vaccine that prevents against infection with Leishmania." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Leishmaniasis vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leishmania vaccine" ; rdfs:seeAlso "MeSH: D054332" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38568 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38568 ] . obo:VO_0000763 obo:IAO_0000115 "A bacterial vaccine that prevents infection with Vibrio cholera." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "cholera vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vibrio cholerae vaccine" ; rdfs:seeAlso "MeSH: D022121" ; rdfs:subClassOf obo:VO_0000566, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_666 ] . obo:VO_0000764 obo:IAO_0000115 "A vaccine that prevents Lyme disease caused by Borrelia burgdorferi." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Borrelia burgdorferi vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lyme disease vaccine" ; rdfs:seeAlso "MeSH: D022123" ; rdfs:subClassOf obo:VO_0003518, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0000765 obo:IAO_0000115 "A bacterial vaccine that prevents against Bordetella pertussis infection that causes pertussis or whooping cough." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Pertussis vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis vaccine" ; rdfs:seeAlso "MeSH: D010567" ; rdfs:subClassOf obo:VO_0000587, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000587 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] ) ] . obo:VO_0000766 obo:IAO_0000115 "A bacterial vaccine that protects against infection with Pseudomonas." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudomonas vaccine" ; rdfs:seeAlso "MeSH: D054406" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_286 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_286 ] . obo:VO_0000767 obo:IAO_0000115 "A bacterial vaccine that protects against diseases caused by various species of Rickettsia. Typhus is any of several similar diseases caused by Rickettsia bacteria. So Rickettsial vaccine is also called typhus vaccine. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "typhus vaccine" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Typhus_vaccine", "WEB: http://www.violinet.org/vaxquery/query_detail.php?c_pathogen_id=108" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rickettsial vaccine" ; rdfs:seeAlso "MeSH: D012290" ; rdfs:subClassOf obo:VO_0003550, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_780 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_780 ] . obo:VO_0000768 obo:IAO_0000115 "A bacterial vaccine that protects against infections by various Salmonella species." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Salmonella" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella vaccine" ; rdfs:seeAlso "MeSH: D022562" ; rdfs:subClassOf obo:VO_0003552, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0000769 obo:IAO_0000115 "A bacterial vaccine that protects against infections with Shigella species." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shigella vaccine" ; rdfs:seeAlso "MeSH: D022281" ; rdfs:subClassOf obo:VO_0003552, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_620 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_620 ] . obo:VO_0000770 obo:IAO_0000115 "A bacterial vaccine that protects against infection with Staphylococcus." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Staph vaccine", "Staphylococcus vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Staphylococcal vaccine" ; rdfs:seeAlso "MeSH: D013209" ; rdfs:subClassOf obo:VO_0003555, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1279 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1279 ] . obo:VO_0000771 obo:IAO_0000115 "BCG Vaccine is a Mycobacterium tuberculosis vaccine that is a live attenuated strain of Mycobacterium bovis (Bacillus Calmette Guerin; BCG)." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Bacillus Calmette Guerin" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BCG vaccine" ; rdfs:seeAlso "CVX: 19" ; rdfs:subClassOf obo:VO_0000077, obo:VO_0001217, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000772 obo:IAO_0000115 "A bacterial vaccine that prevents streptococcal infections." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Streptococcus vaccine" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Streptococcus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcal vaccine" ; rdfs:seeAlso "MeSH: D022541" ; rdfs:subClassOf obo:VO_0003555, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1301 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1301 ] . obo:VO_0000773 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MSP3-LSP with aluminium hydroxide" ; rdfs:seeAlso "PMID: 17280744" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000774 obo:IAO_0000115 "RTS,S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium falciparum circumsporozoite surface antigen. PMID: 15488216." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/?term=15488216" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum RTS,S/AS02A" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:VO_0011218 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000775 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum MSP1 from transgenic mice with Freund's adjuvant" ; rdfs:seeAlso "PMID: 11752405" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010958 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ] . obo:VO_0000776 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. vivax PVS25 with Montanide ISA-720" ; rdfs:seeAlso "PMID: 16291764" ; rdfs:subClassOf obo:VO_0000758, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010957 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ] . obo:VO_0000777 obo:IAO_0000115 "A recombinant E. coli-expressed protein based upon the apical membrane antigen-1 (AMA-1) of the 3D7 clone formulated with the AS02A adjuvant. PMID: 17442466." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum FMP1/AS02A" ; rdfs:seeAlso "PMID: 17442466" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0000894 ; owl:someValuesFrom obo:VO_0010923 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000778 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum ABRA protein vaccine" ; rdfs:seeAlso "PMID: 11489167", "PMID: 9400530" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010926 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000779 obo:IAO_0000115 "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus NP protein." ; obo:IAO_0000117 "YH" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0011387 ; a owl:Class ; rdfs:label "obsolete NP-VRP" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000780 obo:IAO_0000116 "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus GP protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GP-VRP" ; rdfs:subClassOf obo:VO_0000726 . obo:VO_0000781 obo:IAO_0000115 "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP24 protein." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "alphavirus replicon expressing VP24" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VRP expressing VP24" ; rdfs:seeAlso "PMID: 11485406" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010866 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000782 obo:IAO_0000115 "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP30 protein." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "alphavirus replicon expressing VP30" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VRP expressing VP30" ; rdfs:seeAlso "PMID: 11485406" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010867 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000783 obo:IAO_0000115 "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP35 protein." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "alphavirus replicon expressing VP35" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VRP expressing VP35" ; rdfs:seeAlso "PMID: 11485406" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000784 obo:IAO_0000115 "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus VP40 protein." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "alphavirus replicon expressing VP40" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VRP expressing VP40" ; rdfs:seeAlso "PMID: 11485406" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010868 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000785 obo:IAO_0000115 "A DNA vaccine that encodes for a secreted form of Ebola virus GP protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA vaccine expressing sGP" ; rdfs:seeAlso "PMID: 9427604" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010858 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000786 obo:IAO_0000115 "A vaccine combination that includes a DNA vaccine and a recombinant adenovirus Ad5 expressing the same codon-optimized SIV gag gene. The DNA vaccine is used for priming, and the Ad5 vaccine is used for boosting. PMID: 11797011." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA and adenoviral vector Ad5 expressing SIV gag protein" ; rdfs:seeAlso "PMID: 11797011" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010949 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ] . obo:VO_0000787 obo:IAO_0000116 """A gene that is a pathogen gene used for vaccine preparation or a host gene encoding for an immune factor important in induction of protective immunity. a vaccine-associated gene that exists in a pathogen and has been engineered for vaccine develoment. This gene can encode for protective antigen that is overexpressed for vaccine development. This gene can also be a virulence factor that is mutated to attenuate a virulent pathogen with the purpose of making attenuated vaccine.""", "The term 'gene' has appears in several ontologies, such as Sequence Ontology (SO) and Protein Ontology (PRO). We may choose to use a 'gene' term from other ontologies. The 'gene' term in SO has ID: SO:0000704." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "obsolete gene" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000788 obo:IAO_0000115 "A recombinant adenovirus (Ad5) expressing the codon-optimized SIV gag gene. PMID: 11797011." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "adenoviral vector Ad5 expressing SIV gag protein" ; rdfs:seeAlso "PMID: 11797011" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010949 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ] . obo:VO_0000789 obo:IAO_0000115 "A vaccine combination that includes a DNA vaccine and a replication-defective chimeric Ad5 vector with the Ad35 fiber (Ad5/35) that express the same codon-optimized SIV gag gene. The DNA vaccine is used for priming, and the Ad5/35 vaccine is used for boosting. PMID: 16079886." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA and Ad5/35 vector expressing HIV gp160 protein" ; rdfs:seeAlso "PMID: 16079886" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010937 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ] . obo:VO_0000790 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Brucella gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0000791 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "human gene" ; rdfs:subClassOf obo:OGG_0000000002 . obo:VO_0000792 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "mouse gene" ; rdfs:subClassOf obo:OGG_0000000002 . obo:VO_0000793 obo:IAO_0000115 "A Brucella gene that is from B. abortus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Brucella abortus gene" ; rdfs:subClassOf obo:VO_0000790, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_235 ] . obo:VO_0000794 obo:IAO_0000115 "A Brucella abortus gene that has the name wboA and comes from strain 2308. " ; obo:IAO_0000116 "Brucella abortus gene wboA is interrupted in Brucella abortus cattle vaccine RB51." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "wboA from B. abortus strain 2308" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000793, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_359391 ] . obo:VO_0000795 obo:IAO_0000116 "Interferon-gamma (IFN-g) is an indicative of Th1 immune response. It is produced in host immunized by vaccines such as Brucella abortus cattle vaccine RB51." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "mouse Ifng" ; rdfs:subClassOf obo:VO_0000792 . obo:VO_0000796 obo:IAO_0000116 "Interferon-gamma (IFN-g) is an indicative of Th1 immune response." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "human ifng" ; rdfs:subClassOf obo:VO_0000791 . obo:VO_0000797 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "cattle gene" ; rdfs:subClassOf obo:OGG_0000000002 . obo:VO_0000798 obo:IAO_0000116 "Interferon-gamma (IFN-g) is an indicative of Th1 immune response. It is produced in host immunized by vaccines such as Brucella abortus cattle vaccine RB51." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Ifng from cattle" ; rdfs:subClassOf obo:VO_0000797 . obo:VO_0000799 obo:IAO_0000115 "An object property that represents a mutational relation between a vaccine organism and another material (e.g., gene or protein). the mutated material initially exists in the original wildtype organism. " ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "vaccine organism has mutation" . obo:VO_0000800 obo:IAO_0000115 "a storage process that is specifically for vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine storage" ; rdfs:subClassOf obo:OBI_0302893 . obo:VO_0000801 obo:IAO_0000115 "a vaccine storage that is execuated at room temperature. Room temperature is also referred to as ambient temperature. Room temperature denotes a certain temperature within enclosed space at which humans are accustomed. Room temperature is usually indicated by general human comfort, with the common range of 10 degree C (50 degree F) to 28 degree C (82.4 degree F)." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine storage at room temperature" ; rdfs:subClassOf obo:VO_0000800 . obo:VO_0000802 obo:IAO_0000115 "vaccine storage that is executed in refrigerator, usually 0-10^C." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine storage in refrigerator" ; rdfs:subClassOf obo:VO_0000800 . obo:VO_0000803 obo:IAO_0000115 "vaccine storage that is executed in freezer under 0^C." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine storage in freezer" ; rdfs:subClassOf obo:VO_0000800 . obo:VO_0000804 obo:IAO_0000115 "Effectiveness is physical quality that represents the capability of a single physical entity (e.g., vaccine) producing an effect (e.g, protection against a disease)." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "effectiveness" ; rdfs:subClassOf obo:PATO_0001018 . obo:VO_0000805 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "effective" ; rdfs:subClassOf obo:VO_0000804 . obo:VO_0000806 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "ineffective" ; rdfs:subClassOf obo:VO_0000804 . obo:VO_0000807 obo:IAO_0000115 "a vaccine role that indicates the vaccine being a toxoid vaccine. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "toxoid vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0000808 obo:IAO_0000115 "A vaccination process that is implemented fast." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "vaccine rapid implementation" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "rapid vaccination" ; rdfs:subClassOf obo:VO_0000002 . obo:VO_0000809 obo:IAO_0000115 "A measure datum that measures the coverage of vaccination in a specific area during a specific time period." ; obo:IAO_0000117 "YH, MC" ; obo:IAO_0000118 "immunization coverage" ; obo:IAO_0000119 "WEB: http://www.sanofipasteur.com/sanofi-pasteur2/front/index.jsp?siteCode=SP_CORP&codeRubrique=19", "WEB: http://www.who.int/immunization_monitoring/routine/immunization_coverage/en/" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccination coverage" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0000810 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSCAR . CMV promotor is used." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSCAR DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 18022294; PMID: 19712769." ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000811 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccine epitope" ; rdfs:subClassOf obo:OBI_1110034 . obo:VO_0000812 obo:IAO_0000115 "a licensed vaccine role that indicates the vaccine occurs in USA." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "USA licensed vaccine role" ; rdfs:subClassOf obo:VO_0000630 . obo:VO_0000813 obo:IAO_0000115 "a cattle vaccine with license that is used in USA." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "USA licensed cattle vaccine" ; rdfs:subClassOf obo:VO_0000643 . obo:VO_0000814 obo:IAO_0000115 "A dose of vaccine that is used in a vaccination. Vaccination dose may be and may be not the same as the vaccine dose." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccination dose" ; rdfs:subClassOf obo:OBI_0000984 . obo:VO_0000815 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "monthly" ; rdfs:subClassOf obo:PATO_0000044 . obo:VO_0000816 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "biweekly" ; rdfs:subClassOf obo:PATO_0000044 . obo:VO_0000817 obo:IAO_0000115 "A HIV vaccine that is composed of a DNA vaccine expressing conserved, multiple HIV epitopes. PMID: 16359234." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA vaccine expressing multiple HIV epitopes" ; rdfs:seeAlso "PMID: 16359234" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000818 obo:IAO_0000115 "An object property that specifies a relation between a vaccine and a vaccine virmugen. " ; obo:IAO_0000116 """This is a shortcut relation. Domain: vaccine Range: a gene Shortcut: is_specified_output_of some ('preparation of gene mutant vaccine' and (has_specified_input some gene))""" ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has vaccine virmugen" . obo:VO_0000819 obo:IAO_0000115 "A HIV vaccine that is made of recombinant HIV gp120 protein adjuvanted with the adjuvant NanoEmulsion. PMID: 18260780." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant HIV gp120 with adjuvant NanoEmulsion" ; rdfs:seeAlso "PMID: 18260780" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ] . obo:VO_0000820 obo:IAO_0000115 "An Aeromonas bacterial vaccine that is used to protect against Aeromonas salmonicida infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Aeromonas salmonicida vaccine" ; rdfs:subClassOf obo:VO_0000589, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_645 ] . obo:VO_0000821 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Vetech Labs" . obo:VO_0000822 obo:IAO_0000115 "Gag-VRPs is a cocktail vaccine of V3014-packaged VRPs expressing the SIVsm H-4i nonmyristylated matrix-capsid region, full-length gp160, and a secreted form of gp160 (gp140). PMID: 12120997." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Gag-VRPs" ; rdfs:seeAlso "PMID: 10462249", "PMID: 12120997" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ] . obo:VO_0000823 obo:IAO_0000115 "a bacterial vaccine against V. anguillarum infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vibrio anguillarum vaccine" ; rdfs:subClassOf obo:VO_0000566, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_55601 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000566 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_55601 ] ) ] . obo:VO_0000824 obo:IAO_0000115 "A recombinant modified vaccinia Ankara (MVA) expressing HIV Gag, Pol, and Env proteins. PMID: 16472543." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA expressing HIV Gag, Pol and Env proteins" ; rdfs:seeAlso "PMID: 16472543" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000825 obo:IAO_0000115 "A SIV vaccine that is composed of a DNA vaccine and a poxvirus vector expressing the same SIV antigens. PMID: 15258286." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA and poxvirus priming-boosting SIV vaccine" ; rdfs:seeAlso "PMID: 15258286" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ] . obo:VO_0000826 obo:IAO_0000115 "A B. abortus vaccine that is recombinant B. abortus strain 19 vaccine with the p39 gene deletion." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. abortus S19 P39 deletion mutant" ; obo:IAO_0000119 "PMID: 9784574" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus S19 with P39 deletion" ; rdfs:subClassOf obo:VO_0001134, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000827 obo:IAO_0000116 "A Yersinia pestis vaccine that uses a recombinant Ad5-based vector (E1a, partial E1b, and partial E3 deletion) to express Y. pestis V antigen." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AdsecV" ; rdfs:seeAlso "PMID: 17041851" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010876 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000828 obo:IAO_0000115 "A Yersinia pestis vaccine that is a pigmentation negative mutant of Y. pestis derived from a fully virulent strain." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Yersinia EV-76" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yersinia EV76" ; rdfs:seeAlso "PMID: 4988692", "PMID: 8578841" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9479 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000829 obo:IAO_0000115 "A Yersinia pestis subunit vaccine that uses Y. pestis F1 protein as antigen." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Y. pestis F1 protein vaccine" ; rdfs:seeAlso "PMID: 312163", "PMID: 8675324" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010870 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011004 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10114 ] . obo:VO_0000830 obo:IAO_0000115 "A Y. pestis subunit vaccine that uses recombinant F1 and V antigens. PMID: 312163." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rF1 + rV vaccine" ; rdfs:seeAlso "PMID: 10930691", "PMID: 12922126", "PMID: 15908389" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0000831 obo:IAO_0000115 "A Y. pestis subunit vaccine that uses recombinant Y. pestis V antigen. PMID: 7622205." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant Y. pestis V antigen vaccine" ; rdfs:seeAlso "PMID: 7622205" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010874 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000832 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "modified Y. pestis with TLR4-stimulating LPS" ; rdfs:seeAlso "PMID: 16980981" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000833 obo:IAO_0000115 "A Yersinia pestis subunit vaccine that contains staphylococcal protein A-V antigen fusion peptide (PAV). PMID: 7622225." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yersinia PAV" ; rdfs:seeAlso "PMID: 7622225" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000834 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant Y. pestis YopD protein vaccine" ; rdfs:seeAlso "PMID: 10024607", "PMID: 8890210" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010878 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000835 obo:IAO_0000116 "In vitro-cultured merozoites, chemically inactivated" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Epm vaccine" ; rdfs:subClassOf obo:VO_0000935, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000205 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000836 obo:IAO_0000115 "A Y. pestis subunit vaccine that uses Y. pestis YscF protein as antigen. PMID: 15978133." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Y. pestis YscF subunit vaccine" ; rdfs:seeAlso "PMID: 15978133" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000837 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "microencapsulated Caf1 and LcrV vaccine" ; rdfs:seeAlso "PMID: 16546306" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000838 obo:IAO_0000116 "Live temperature-sensitive mutant strain for subcutaneous or intramuscular injection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ovilis Enzovax" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000839 obo:IAO_0000116 "Fowlpox virus-vectored H5" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trovac AI H5" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000840 obo:IAO_0000115 "A Y. pestis vaccine that uses the recombinant V10 (rV10), a variant (lacking residues 271 to 300) of Yersinia pestis LcrV. PMID: 16861680." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant Yersinia rV10 vaccine" ; rdfs:seeAlso "PMID: 16861680" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000841 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Pfizer Animal Health" . obo:VO_0000842 obo:IAO_0000116 "Killed oral vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AquaVac ERM" ; rdfs:subClassOf obo:VO_0001035, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8022 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001174 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000843 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline leukemia virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11768 ] . obo:VO_0000844 obo:IAO_0000116 "Live temperature-sensitive mutant strain; spray inhalation or drinking water" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Art Vax" ; rdfs:subClassOf obo:VO_0001114, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9005 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001174 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000845 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VSV vector expressing Y. pestis lcrV" ; rdfs:seeAlso "PMID: 16959385" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000846 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "BIOPHARM" . obo:VO_0000847 obo:IAO_0000115 "A formalin-inactivated preparation that was manufactured by Cutter Biologicals (a division of Miles Laboratories, Inc.). It is now available only from Greer Laboratories, Inc. The killed or inactivated plague vaccine is prepared from Y. pestis organisms grown in artificial media and then inactivated in formaldehyde. URL: http://www.cdc.gov/mmwr/preview/mmwrhtml/00044836.htm" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Plague vaccine USP" ; rdfs:seeAlso "PMID: 8578841" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000848 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000848 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Cutter Biological" . obo:VO_0000849 obo:IAO_0000115 "IMPROVAC is a vaccine that stimulates the pig‚Äôs own immune system to produce specific antibodies against GnRF. This temporarily inhibits testes function and thus stops the production and accumulation of boar taint-causing compounds." ; obo:IAO_0000116 "Peptide-protein conjugate and water-miscible adjuvant; control of boar taint" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.improvac.co.nz/sites/improvac/en-nz/Pages/productoverview.aspx" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Improvac" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000759, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000972 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000850 obo:IAO_0000115 "a vaccine component that is added to the immunogen by the vaccine manufacturer for a specific purpose. Additives include adjuvants, preservatives and stablizers, as well as materials that are added to affect pH and isotonicity." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73." ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine additive" ; rdfs:subClassOf obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000415 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000179 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000415 ] ) ] . obo:VO_0000851 obo:IAO_0000115 """vaccine preservative is an vaccine additive that is added to a vaccine formulation to prevent the growth of bacteria or fungi that inadvertently may be introduced into the vaccine during use. Ref: Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73.""" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "antimicrobial agent in vaccine" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine preservative" ; rdfs:subClassOf obo:VO_0000850, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000885 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000179 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000885 ] ) ] . obo:VO_0000852 obo:IAO_0000116 "Killed vaccine against periodontitis" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Periovac" ; rdfs:subClassOf obo:VO_0000865, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9615 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_111105 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000879 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000853 obo:IAO_0000115 "a vaccine additive that helps to protect the vaccine from adverse conditions such as the freeze-drying process (for those vaccines that are freeze-dried) or heat." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 75." ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine stabilizer" ; rdfs:subClassOf obo:VO_0000850, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003026 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000179 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003026 ] ) ] . obo:VO_0000854 obo:IAO_0000115 "a vaccine component that remains from the vaccine manufacturing process." ; obo:IAO_0000116 "Although no all manufacturing residuals may be identified and quantified, their presence and quantity is assumed to be constant because of the constancy of the manufacturing process." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 73." ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine residual" ; rdfs:subClassOf obo:VO_0000179 . obo:VO_0000855 obo:IAO_0000115 "a vaccine residual that is used to inactivate bacteria and viruses or to detoxify bacterial toxins. For example, formaldehyde is a frequently used inactivation agent in vaccine preparation." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 78." ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "inactivation residual in vaccine" ; rdfs:subClassOf obo:VO_0000854 . obo:VO_0000856 obo:IAO_0000115 "a vaccine residual that is generatead from cell culture for vaccine preparation. Examples include: antibiotics, sensitizing substances, bacterial and cellular residuals, and adventitious agents." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "Finn TM and Egan W, in Vaccines fifth edition, 2008. Page 78-81." ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "cell culture residual in vaccine" ; rdfs:subClassOf obo:VO_0000854 . obo:VO_0000857 obo:IAO_0000116 "Immune correlate of protection is a host immune response to vaccine that correlates with protective induced by the vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced immune correlate of protection" ; rdfs:subClassOf obo:VO_0000288, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000287 ] . obo:VO_0000858 obo:IAO_0000115 "Serological correlate of protection is an immune correlate of protection that is reflected by serologic antibody levels." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "serologic correlate of protection" ; rdfs:subClassOf obo:VO_0000857 . obo:VO_0000859 obo:IAO_0000115 "A cell mediated immune correlate of protection is an immune correlate of protection that is reflected by a cell mediated immune response." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "cell mediated immune correlate of protection" ; rdfs:subClassOf obo:VO_0000857 . obo:VO_0000860 obo:IAO_0000115 "Vaccine effectiveness is an effectiveness associated with a vaccine." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "Hadler TC, et al. Immunization in developing countries. In: Vaccines. Editors: Plotkin S, et al. 2008. p1542-71." ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccine effectiveness" ; rdfs:subClassOf obo:VO_0000804 . obo:VO_0000861 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Bioproperties" . obo:VO_0000862 obo:IAO_0000115 "Canada is a country that exists in north America." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "Canada" ; rdfs:subClassOf obo:VO_0010632 . obo:VO_0000863 obo:IAO_0000116 "In vitro-cultured supernatant antigens, reduce clinical disease" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pirodog" ; rdfs:subClassOf obo:VO_0001074, obo:VO_0002792, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9615 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000864 obo:IAO_0000115 "a licensed status that occurs in Canada." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "Canada licensed vaccine role" ; rdfs:subClassOf obo:VO_0000630 . obo:VO_0000865 obo:IAO_0000115 "a bacterial vaccine against Porphyromonas gulae infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porphyromonas gulae vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_836 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_836 ] . obo:VO_0000866 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluviral S/F" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000867 obo:IAO_0000115 "Influvac is an Influenza virus vaccine that is manufactured by Solvay Pharma." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influvac" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000869 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000868 obo:IAO_0000115 "Vaxigrip is an Influenza virus vaccine that is manufactured by 'Sanofi Pasteur Limited." ; obo:IAO_0000117 "YH, Melanie" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaxigrip" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000869 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Solvay Pharmaceuticals" . obo:VO_0000870 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Babesia bigemina vaccine by local veterinary institutes" ; rdfs:subClassOf obo:VO_0001033, obo:VO_0003046, [ a owl:Restriction ; owl:hasValue obo:VO_0001079 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000871 obo:IAO_0000116 "Canarypox virus-vectored vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Purevax Feline Rabies" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000872 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Babesia bovis vaccine by local veterinary institutes" ; rdfs:subClassOf obo:VO_0000925, [ a owl:Restriction ; owl:hasValue obo:VO_0001079 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000873 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "pGPA-incorporated microemulsion" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PGA/ME" ; rdfs:seeAlso "PMID: 16730934" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000874 obo:IAO_0000115 "Anthrax Spore Vaccine is a B. anthracis vaccine that is prepared with a relatively nonpathogenic, noncapsulated variant strain of B. anthracis, originally developed at the Onderstepoort Laboratory, Pretoria, South Africa. Further work was conducted in England, India and in many other countries. Vaccine Strain is Sterne 34F2. The vaccine is a suspension of viable Bacillus anthracis spores in saponin." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "B. anthracis Sterne strain spore vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Anthrax Spore Vaccine" ; rdfs:seeAlso "PMID: 3084385" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10141 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9788 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9935 ] . obo:VO_0000875 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pSecTag-PA83" ; rdfs:seeAlso "PMID: 15293452" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000876 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pCMV/ER-PA83" ; rdfs:seeAlso "PMID: 15293452" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0000877 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Websters Animal Health" . obo:VO_0000878 obo:IAO_0000116 "Canarypox virus-vectored vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RECOMBITEKEquine WNV" ; rdfs:subClassOf obo:VO_0000752, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000879 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "Porphyromonas denticanis" ; rdfs:subClassOf obo:NCBITaxon_836 . obo:VO_0000880 obo:IAO_0000115 "pCLF4 is a Bacillus anthracis vaccine that contains the N-terminal region (amino acids [aa] 10-254) of Bacillus anthracis LF cloned into the pCI expression plasmid." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pCLF4" ; rdfs:seeAlso "PMID: 11401993", "PMID: 15068841" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010873 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9986 ] . obo:VO_0000881 obo:IAO_0000115 "Equity Oestrus Control Vaccine for Horses is prepared from an analogue of gonadotropin releasing factor (GnRF) linked to a carrier protein. It has an adjuvant that enhances the level and duration of the immune response to GnRF with minimal injection site reactivity. It is used as an aid in the control of oestrus and oestrus-related behaviour in fillies and mares not intended for breeding." ; obo:IAO_0000116 "Peptide-protein conjugate and proprietary adjuvant (immunostimulating complex); control of estrus and estrus-related behavior" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Equity Oestrus Control Vaccine for Horses" ; obo:IAO_0000119 "WEB: https://www.pfizeranimalhealth.com.au/products/352/equityreg-oestrus-control-vaccine.aspx" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equity" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000759, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000972 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000882 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "single-dose Vaxigrip" ; rdfs:subClassOf obo:VO_0000868 . obo:VO_0000883 obo:IAO_0000116 "The difference between single-dose and multi-dose Vaxigrip is that multi-dose Vaxigrip contains preservative thimoseral.", "We still have not made it defined class since we still need to figure out how to represent multi-dose vs. single dose. The previous method discussed brief needs vetting. --YH" ; obo:IAO_0000117 "YH, Melanie, and Allen" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "multi-dose Vaxigrip" ; rdfs:subClassOf obo:VO_0000868, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ] . obo:VO_0000884 obo:IAO_0000115 "A mineral salt vaccine adjuvant that is composed of some aluminum compound." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "aluminum vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000093 . obo:VO_0000885 obo:IAO_0000115 "a role inhers in a vaccine component that when added into a vccine formmulation, it can prevent the growth of bacteria or fungi that inadvertently may be introduced into the vaccine during administrating process or the manufacturing process." ; obo:IAO_0000117 "YH,YL" ; obo:IAO_0000119 "P73 Chapter 6, Vaccine 5th edition by Plotkin, S. et al." ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:comment "The CFR requires that, with certain defined exceptions, preservatives must be added to mulitdose vials of vaccine. (P73 Chapter 6, Vaccine 5th edition by Plotkin, S. et al.)" ; rdfs:label "vaccine preservative role" ; rdfs:subClassOf obo:VO_0000415 . obo:VO_0000886 obo:IAO_0000115 "A route of administration that located in the mouth" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "oral route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000887 obo:IAO_0000115 "A route of administration that inject the material(such as vaccines, allergens) into the skin itself." ; obo:IAO_0000117 "YH,YL" ; obo:IAO_0000118 "intradermal injection route" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intradermal route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0000888 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "phenol vaccine preservative" ; rdfs:subClassOf obo:VO_0000851 . obo:VO_0000889 obo:IAO_0000116 "Recombinant ApxII, TbpB, CysL, OmlA(1), and OmlA(2) proteins" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PleuroStar APP" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000964 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000890 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Colorado Serum Company CZ Veterinaria" . obo:VO_0000891 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "phenoxy ethanol vaccine preservative" ; rdfs:subClassOf obo:VO_0000851, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000885 ] . obo:VO_0000892 obo:IAO_0000117 "YH, ZX" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Biken" . obo:VO_0000893 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Schering-Plough" . obo:VO_0000894 obo:IAO_0000115 "A 'has subunit vaccine antigen' relation that indicates the antigen is protective." ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has subunit vaccine protective antigen" ; rdfs:subPropertyOf obo:VO_0000525 . obo:VO_0000895 obo:IAO_0000117 "YH, ZX" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Baxter Healthcare Corporation" . obo:VO_0000896 obo:IAO_0000117 "YH, ZX" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Merck Frosst" . obo:VO_0000897 obo:IAO_0000115 "Age at vaccination is the age of an experiment animal at the time of vaccination." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "age at vaccination" ; rdfs:subClassOf obo:PATO_0000011 . obo:VO_0000898 obo:IAO_0000116 "Culture-derived schizonts" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Theileria annulata vaccine by local veterinary institutes" ; rdfs:subClassOf obo:VO_0000909, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_77054 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001079 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000899 obo:IAO_0000115 "dose is a measurement data that measures the quantity of something that may be eaten by or administered to an organism, or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses." ; obo:IAO_0000117 "Melanie Courtot", "Oliver He" ; obo:IAO_0000119 "http://en.wikipedia.org/wiki/Dose_%28biochemistry%29" ; obo:IAO_0000231 obo:IAO_0000228 ; obo:IAO_0100001 obo:OBI_0000984 ; a owl:Class ; rdfs:comment "obsolete on 2/1/2020, using the OBI dose term (OBI_0000984) instead." ; rdfs:label "obsolete dose" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000900 obo:IAO_0000115 "A dose of a virulent pathogen used for a vaccine challenge process." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "challenge dose" ; rdfs:subClassOf obo:OBI_0000984 . obo:VO_0000901 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Boehringer-Ingelheim Vetmedica, Inc" . obo:VO_0000902 obo:IAO_0000116 "Canarypox virus-vectored vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PROTEQ-FLU (European Union)" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000903 obo:IAO_0000115 "Secondary vaccination is a vaccination that is performed immediately after the primary or the first vaccination." ; obo:IAO_0000117 "YH, Thom Todd" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "secondary vaccination" ; rdfs:subClassOf obo:VO_0000708, [ a owl:Restriction ; owl:onProperty obo:BFO_0000062 ; owl:someValuesFrom obo:VO_0000707 ] . obo:VO_0000904 obo:IAO_0000117 "YH, ZX" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "SBL Vaccine" . obo:VO_0000905 obo:IAO_0000117 "YH, ZX" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Wyeth Canada" . obo:VO_0000906 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Eimeria vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5800 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5800 ] . obo:VO_0000907 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "surface antigens from the zona pellucida" ; rdfs:subClassOf obo:OBI_1110034 . obo:VO_0000908 obo:IAO_0000115 "A relation that specifies a company that distributes a product (e.g., vaccine). The company is very likely not the manufacturer of the product." ; obo:IAO_0000117 "Allen Xiang", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "is_distributed_by" . obo:VO_0000909 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Theileria annulata vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5874 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5874 ] . obo:VO_0000910 obo:IAO_0000115 "vaccine allergen is a material entity that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals who has been vaccinated with a vaccine." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/B/excipient-table-2.pdf" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccine allergen" ; rdfs:subClassOf obo:BFO_0000040 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:BFO_0000040 [ a owl:Restriction ; owl:onProperty obo:RO_0000091 ; owl:someValuesFrom obo:VO_0000713 ] ) ] . obo:VO_0000911 obo:IAO_0000115 "passive immunization that Immunity is transferred from mother to fetus through placental transfer of IgG or colostral transfer of IgA." ; obo:IAO_0000117 "YL" ; obo:IAO_0000119 "http://pathmicro.med.sc.edu/ghaffar/immunization-ver2.htm" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "passive immunization using natural maternal antibody" ; rdfs:subClassOf obo:VO_0000492 . obo:VO_0000912 obo:IAO_0000115 "chicken egg protein allergen is a vaccine allergen that is composed of chicken egg protein." ; obo:IAO_0000116 """Egg protein may come from NCIS thesaurus egg - poultry, combination of minimal anatomy terminology and NCBI taxonomy... Eventually, this term chicken egg protein allergen may become a cross product of sevreal ontology terms.""" ; obo:IAO_0000117 "YH, ZX, MC" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "chicken egg protein allergen" ; rdfs:subClassOf obo:VO_0000910 . obo:VO_0000913 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "latex vaccine allergen" ; rdfs:subClassOf obo:VO_0000910 . obo:VO_0000914 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Virbac" . obo:VO_0000915 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "gelatin vaccine allergen" ; rdfs:subClassOf obo:VO_0000910 . obo:VO_0000916 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "protamine sulfate vaccine allergen" ; rdfs:subClassOf obo:VO_0000910 . obo:VO_0000917 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "polymyxin B vaccine allergen" ; rdfs:subClassOf obo:VO_0000910 . obo:VO_0000918 obo:IAO_0000116 "Canarypox virus-vectored vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EURIFEL FeLV" ; rdfs:subClassOf obo:VO_0000843, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011068 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000919 obo:IAO_0000115 "the vaccine component that is used as antigen to produce an immune responce protect against the specific pathogen or disease." ; obo:IAO_0000116 "This is a modified or partial form of the virus, bacteria or the toxin that causes the disease against which the vaccine protects. The vaccine antigen is altered from its original form so it no longer causes disease but it can produce an immune response.(Vaccine components FactSheet of NCIRS)" ; obo:IAO_0000117 "YL, YH" ; obo:IAO_0000118 "vaccine antigenic component" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "To create this term for cover some other vaccines such as cancer vaccine and so on." ; rdfs:label "vaccine antigen" ; rdfs:subClassOf obo:OBI_1110034, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000237 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000179 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000237 ] ) ] . obo:VO_0000920 obo:IAO_0000115 "a cell culture residual in vaccine that is bovine albumin." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "bovine albumin cell culture residual in vaccine" ; rdfs:subClassOf obo:VO_0000856 . obo:VO_0000921 obo:IAO_0000115 "a cell culture residual in vaccine that is bovine serum." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "bovine serum cell culture residual in vaccine" ; rdfs:subClassOf obo:VO_0000856 . obo:VO_0000922 obo:IAO_0000115 "a vaccine stablizer that is based on monosodium glutamate. " ; obo:IAO_0000117 "YL,YH" ; obo:IAO_0000118 "C5H8NNaO4" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "http://www.novaccine.com/vaccine-ingredients/results.asp?sc=13" ; rdfs:label "monosodium glutamate stabliizer" ; rdfs:subClassOf obo:VO_0003035, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64220 ] . obo:VO_0000923 obo:IAO_0000116 "Modified live virus" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RECOMBITEK Corona MLV" ; rdfs:subClassOf obo:VO_0000932, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9615 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000924 oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "glutaraldehyde vaccine additive" ; rdfs:subClassOf obo:VO_0000851, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000885 ] . obo:VO_0000925 obo:IAO_0000116 "Infected blood from splenectomized calves" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Babesia bovis vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5865 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5865 ] . obo:VO_0000926 obo:IAO_0000115 "a cell culture residual in vaccine that is human albumin." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "human albumin cell culture residual in vaccine" ; rdfs:subClassOf obo:VO_0000856 . obo:VO_0000927 obo:IAO_0000115 "a cell culture residual in vaccine that is human serum." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "human serum cell culture residual in vaccine" ; rdfs:subClassOf obo:VO_0000856 . obo:VO_0000928 obo:IAO_0000116 "Reference: http://www.raboral.com/", "Vaccinia virus recombinant" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Raboral" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_13488 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9615 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9654 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000929 obo:IAO_0000115 "a vaccine stabilizer that is a polysorbate 20. It encourages the suspension of one liquid in another and has mild toxicity." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Reference: http://www.sciencelab.com/msds.php?msdsId=9926640 ", "http://www.novaccine.com/vaccine-ingredients/results.asp?sc=95" ; rdfs:label "polysorbate 20 vaccine stabilizer" ; rdfs:subClassOf obo:VO_0000853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003026 ] . obo:VO_0000930 obo:IAO_0000115 "a vaccine emulsifier that uses polysorbate 80, also known as polyoxyethylene sorbitan monooleate or Tween‚Ñ¢ 80." ; obo:IAO_0000117 "YH,YL" ; obo:IAO_0000118 "Tween 80 vaccine emulsifier" ; obo:IAO_0000119 "WEB: http://www.wisegeek.org/what-is-polysorbate-80.htm " ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Tween 80 is an amber-colored, viscous liquid with a slightly bitter taste. The product is a derivative of sorbitol and oleic acid. " ; rdfs:label "polysorbate 80 vaccine emulsifier" ; rdfs:subClassOf obo:VO_0000310 . obo:VO_0000931 obo:IAO_0000115 "a cell culture residual in vaccine that is residual protein from cell culture. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine residual protein from cell culture" ; rdfs:subClassOf obo:VO_0000856 . obo:VO_0000932 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "canine coronavirus vaccine" ; rdfs:subClassOf obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ] . obo:VO_0000933 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:hasAlternativeId "VO:0004262" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli CS3 in PLGA microspheres" ; rdfs:seeAlso "VIOLIN Vaccine ID: 3095" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83334 ] . obo:VO_0000934 obo:IAO_0000115 "a vaccine stabilizer that is specifically made by sorbitol." ; obo:IAO_0000117 "YH, YL" ; obo:IAO_0000118 "glucitol" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Sorbitol, also known as glucitol, is a sugar alcohol that the human body metabolizes slowly. It can be obtained by reduction of glucose, changing the aldehyde group to a hydroxyl group. Sorbitol is found in apples, pears, peaches, and prunes. It is synthesized by sorbitol-6-phosphate dehydrogenase, and converted to fructose by succinate dehydrogenase and sorbitol dehydrogenase. Succinate dehydrogenase is an enzyme complex that participates in the citric acid cycle. (wikipedia)" ; rdfs:label "sorbitol vaccine stabilizer" ; rdfs:subClassOf obo:VO_0003034, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_30911 ] . obo:VO_0000935 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Sarcocystis neurona vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_42890 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_42890 ] . obo:VO_0000936 obo:IAO_0000115 "A vaccine that is made of a TK-negative (TK -) and gI/gE-negative (gI/gE -) pseudorabies virus (PRV) mutant to protect pigs against Aujeszky's disease. Aujeszky's disease is also known as pseudorabies. It is a disease primarily of pigs and is caused by porcine herpesvirus 1. This disease is characterized by respiratory, reproductive and nervous signs." ; obo:IAO_0000116 """gE- and thymidine kinase-deleted marker vaccine""" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Suvaxyn Aujeszky" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000205 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000937 obo:IAO_0000115 "a cell culture residual in vaccine that is sucrose albumin." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "sucrose albumin cell culture residual in vaccine" ; rdfs:subClassOf obo:VO_0000856 . obo:VO_0000938 obo:IAO_0000115 "A synthetic vaccine adjuvant that is derived from Xanthomonas campestris, has a pentasaccharide repeating unit structure, and its terminus contains a mannose moiety which acts as a toll-like receptor 2 agonist." ; obo:IAO_0000117 "Asiyah Yu Lin" ; obo:IAO_0000119 "PMID:19608270", "http://www.sciencedirect.com/science/article/pii/S0142961209006371" ; a owl:Class ; rdfs:label "xanthan gum vaccine ajuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0000939 obo:IAO_0000115 "a cell culture residual in vaccine that is from yeast extract." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "yeast extract cell culture residual in vaccine" ; rdfs:subClassOf obo:VO_0000856 . obo:VO_0000940 obo:IAO_0000115 "a cell culture residual in vaccine that is yeast protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "yeast protein cell culture residual in vaccine" ; rdfs:subClassOf obo:VO_0000856 . obo:VO_0000941 obo:IAO_0000116 "DNA vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Apex-IHN" ; rdfs:subClassOf obo:VO_0012165, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8015 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000971 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000942 obo:IAO_0000118 "DTP-Hib vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Pertussis-Haemophilus b vaccine" ; rdfs:subClassOf obo:VO_0000195, obo:VO_0000662, obo:VO_0000738, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] . obo:VO_0000943 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Poliovirus vaccine" ; rdfs:subClassOf obo:VO_0000732, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:NCBITaxon_12080 obo:NCBITaxon_12083 obo:NCBITaxon_12086 ) ] ] . obo:VO_0000944 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V. cholerae and E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041, obo:VO_0000566, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_562 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_666 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_562 obo:NCBITaxon_666 ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_562 obo:NCBITaxon_666 ) ] ] . obo:VO_0000945 obo:IAO_0000115 "A Measles virus vaccine that is also used against Rubella virus infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles-Rubella vaccine" ; rdfs:subClassOf obo:VO_0000654, obo:VO_0010637, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11041 ] . obo:VO_0000946 obo:IAO_0000115 "A vaccine that protects against, Diphtheria, Tetanus, Pertussis (whooping cough), Polio, Hepatitis B, and Haemophilus influenzae type b." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTaP/IPV/HepB/Hib vaccine" ; obo:IAO_0000119 "https://www.nhsinform.scot/healthy-living/immunisation/vaccines/the-6-in-1-vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine" ; rdfs:subClassOf obo:VO_0000744, obo:VO_0000746, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0000947 obo:IAO_0000116 "Live flavivirus chimera vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PreveNile" ; rdfs:subClassOf obo:VO_0000752, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000948 obo:IAO_0000115 "a bacterial vaccine against S. equi infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus equi vaccine" ; rdfs:subClassOf obo:VO_0000772, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1336 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1336 ] . obo:VO_0000949 obo:IAO_0000115 "a bacterial vaccine against Mycoplasma gallisepticum infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycoplasma gallisepticum vaccine" ; rdfs:subClassOf obo:VO_0000604, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2096 ] . obo:VO_0000950 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella typhi-Hepatitis A vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000646, obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90370 ] . obo:VO_0000951 obo:IAO_0000116 "Baculovirus recombinant E2 protein without emulsion" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bayovac CSF E2" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001179 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000952 obo:IAO_0000118 "Tick-borne virus vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dhori virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11318 ] . obo:VO_0000953 obo:IAO_0000115 "Pharyngeal mucosal route is an oral route of administration." ; obo:IAO_0000117 "TT, YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "pharyngeal mucosal route" ; rdfs:subClassOf obo:VO_0000886 . obo:VO_0000954 obo:IAO_0000116 "Chimera virus on NDV backbone; field trials in 2007" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Intervet Avian Influenza virus vaccine" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8782 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000642 [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] ) ] . obo:VO_0000955 oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "host survival to pathogen challenge after vaccination" ; rdfs:subClassOf obo:OBI_0000070 . obo:VO_0000956 obo:IAO_0000115 "a B. abortus vaccine that uses a conjugate vaccine format" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus conjugate vaccine" ; rdfs:subClassOf obo:VO_0000108, obo:VO_0000195, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ] . obo:VO_0000957 obo:IAO_0000115 "a B. abortus vaccine that uses a recombinant vector. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus recombinant vector vaccine" ; rdfs:subClassOf obo:VO_0000108, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ] . obo:VO_0000958 obo:IAO_0000115 "A vaccine that protects against Herpes simplex virus type 1." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Herpes simplex virus type 1" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus type 1 vaccine" ; rdfs:subClassOf obo:VO_0000727, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0000959 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Embrex" . obo:VO_0000960 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "killed infectious bursal disease Virus vaccine" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] . obo:VO_0000961 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated infectious bursal disease virus vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ] . obo:VO_0000962 obo:IAO_0000115 "An E. coli vaccine that uses a live mutant by knocking out one gene(s) from a wild type E. coli." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant E. coli mutant vaccine" ; rdfs:subClassOf obo:VO_0000619 . obo:VO_0000963 obo:IAO_0000115 "an E. coli vaccine that uses toxoid antigen" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli toxoid vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0000964 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Novartis Animal Health" . obo:VO_0000965 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PubMed: http://www.ncbi.nlm.nih.gov/pubmed/9682399" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "potato expressed E. coli LB-T vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 276" ; rdfs:subClassOf obo:VO_0000628 . obo:VO_0000966 obo:IAO_0000115 "An E. coli vaccine that uses a recombinant vaccine vector to express an E. coli antigen(s)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant vaccine vector E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0000967 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PubMed: http://www.ncbi.nlm.nih.gov/pubmed/23035176" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCG-Stx2B" ; rdfs:subClassOf obo:VO_0000966 . obo:VO_0000968 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pBLUESCRIPT." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Davidson College - pBLUESCRIPT: Plasmids and Phages Combine For pBluescript [http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/Keogh/plasmids.html]" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Derived from pUC vectors; cross between phages and plasmids and therefore in a special category called \"phagemids\" (Davidson College - pBLUESCRIPT)", "The plasmid length is: 2961" ; rdfs:label "pBLUESCRIPT DNA vaccine plasmid" ; rdfs:seeAlso "DNAVaxDB Plasmid ID: 180" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000969 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label nkCMVint." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "A pUC-18-based plasmid; also contains intron A and an SV40 polyadenylation termination signal sequence. It has a CMV promoter." ; rdfs:label "nkCMVint DNA vaccine plasmid" ; rdfs:seeAlso "DNAVaxDB Plasmid ID: 181", "PMID: 9234529" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0001006 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000970 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli Tir protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 3087" ; rdfs:subClassOf obo:VO_0000628 . obo:VO_0000971 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Aqua Health"@en ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Novartis" . obo:VO_0000972 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "luteinizing hormone-releasing hormone" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "LHRH" ; rdfs:subClassOf obo:FMA_12278 . obo:VO_0000973 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli Shiga toxin 2B vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 282" ; rdfs:subClassOf obo:VO_0000628 . obo:VO_0000974 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "inactivated E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0000975 obo:IAO_0000115 "An E. coli vaccine against uropathogenic E. coli infections" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "UPEC vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "uropathogenic E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0000976 obo:IAO_0000115 "An E. coli vaccine against extraintestinal pathogenic E. coli infections" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "ExPEC vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "extraintestinal pathogenic E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0000977 obo:IAO_0000115 "An E. coli vaccine against enterohemorrhagic E. coli infections" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "EHEC vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "enterohemorrhagic E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0000978 obo:IAO_0000117 "Kallan Roan, Yongqun He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm335836.htm" ; obo:VO_0003099 "Flublok" ; obo:VO_0003158 "Influenza Vaccine" ; obo:VO_0003160 "For active immunization against disease caused by influenza virus subtypes A and type B contained in the vaccine. Flublok is approved for use in persons 18 years of age and older." ; obo:VO_0003162 "125285" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Flublok" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003069 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000979 obo:IAO_0000116 "Live or inactivated gE-deleted marker vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovilis IBR Marker" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000980 obo:IAO_0000117 "Kallan Roan, Yongqun He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm328629.htm" ; obo:VO_0003099 "FLUCELVAX" ; obo:VO_0003158 "Influenza Vaccine" ; obo:VO_0003160 "For active immunization of persons 4 years of age and older for the prevention of influenza disease caused by influenza virus subtypes A and type B contained in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM329134.pdf" ; obo:VO_0003162 "125408" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Flucelvax" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003164 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000981 obo:IAO_0000116 "Baculovirus recombinant E2 protein without emulsion" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcilis Pesti" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000982 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FluMist Quadrivalent" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000343 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000694 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000983 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluarix Quadrivalent" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000984 obo:IAO_0000115 "a tetanus vaccine manusfactured by Sanofi Pasteur Inc. that is only for booster use (not recommended for primary immunization)" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142732.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tetanus Toxoid (for Boost use Only) by Sanofi Pasteur Inc" ; rdfs:subClassOf obo:VO_0000640, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000985 obo:IAO_0000115 "a viral vaccine that is used to protect against fowl pox virus infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "fowl pox vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ] ) ] . obo:VO_0000986 obo:IAO_0000117 "YL" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000461 ; a owl:Class ; rdfs:label "obsolete avian influenza vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0000987 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bovine rhinotracheitis vaccine" ; rdfs:subClassOf obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] ) ] . obo:VO_0000988 obo:IAO_0000116 "Infection followed by drug treatment" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Theileria parva vaccine by local veterinary institutes" ; rdfs:subClassOf obo:VO_0001061, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001058 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000989 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Novus International" . obo:VO_0000990 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bovine parainfluenza 3 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] ) ] . obo:VO_0000991 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pDONR221. The plasmid length is 4762." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2394/", "Invitrogen: http://tools.invitrogen.com/content/sfs/manuals/gateway_pdonr_vectors.pdf", "pDONR221 Sequence: http://tools.invitrogen.com/content/sfs/vectors/pdonr221_seq.txt" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pDONR221 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000992 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCN3. The plasmid promoter is CMV." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCN3 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 19596416; PMID: 21059395." ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000993 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label V1R." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "V1R DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 11797011; PMID: 15258286" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000994 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Toxoplasma gondii vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0000995 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pVAC1 3.0. The manufacturer is Invitrogen." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVAC1 3.0 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 20884037" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000996 obo:IAO_0000115 "SpayVac is a contraceptive vaccine that has proven highly effective in deer and can be used to control populations. Refernce: http://terramar.bc.ca/." ; obo:IAO_0000116 "Crude ZPA preparation; supplied to research groups only", "no longer available" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SpayVac" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000759, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000907 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9850 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001069 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0000997 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSin-CMV-Vac. The promoter is CMV." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSin-CMV-Vac DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 22702835; PMID: 23637502" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000998 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pGACAG. The promoter is CAG and the antibiotics resistance gene is kanamycin." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pGACAG DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 17203206" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0000999 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pVCL1012. The promoter is HCMV and the manufacturer is Vical Inc." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVCL1012 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 15652666" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0001000 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSCA1." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSCA1 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 22819169" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0001001 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Biomune" . obo:VO_0001002 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label phCMV1. This plasmid is 4200 base pairs long, has a CMV promoter, contains kanamycin and neomycin antibiotics resistance genes, and is manufactured by Genlantis. " ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "WEB: http://www.genlantis.com/faq-phcmv.html" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "phCMV1 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 19540885" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0001003 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCJ-3. This plasmid has a CMV promoter and a kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCJ-3 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 16949850" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0001004 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/V5-His. This plasmid has a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA3.1/V5-His DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 22445688" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001005 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSecTag2 C. This plasmid is 5167 base pairs long, has a CMV promoter and ampicillin and zeocin resistance genes." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "WEB: http://tools.invitrogen.com/content/sfs/manuals/psectag2_man.pdf" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSecTag2 C DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0000023 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001006 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Vical, Inc." . obo:VO_0001007 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pBC12/CMV/IL-2." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "NIH AIDS Reagent Program - pBC12/CMV/IL-2: [https://www.aidsreagent.org/reagentdetail.cfm?t=expression_vectors&id=159]" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Derived from plasmid pBC12/CMV; expresses IL-2 (NIH AIDS Reagent Program - pBC12/CMV/IL-2). Its length is: 4732." ; rdfs:label "pBC12/CMV/IL-2 DNA vaccine plasmid" ; rdfs:seeAlso "DNAVaxDB Plasmid ID: 182" ; rdfs:subClassOf obo:VO_0000435, [ a owl:Restriction ; owl:hasValue obo:VO_0001006 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001008 obo:IAO_0000116 "Cultured trophozoites, reduces disease and cyst shedding" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Giardiavax" ; rdfs:subClassOf obo:VO_0001083, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9615 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000205 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001009 obo:IAO_0000115 "The plant-based Newcastle disease virus vaccine is a Newcastle disease virus vaccine that is developed by Dow AgroSciences LLC. It uses technology discovered at Washington University. It is the first plant-made animal vaccine approved for sale in the United States." ; obo:IAO_0000116 "HN recombinant produced in plant cell lines (registered but not on market)" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "plant-based Newcastle disease virus vaccine" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001219 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001010 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Promega" . obo:VO_0001011 obo:IAO_0000115 """A shortcut relation that equals to: 'processed material' and (is_specified_output_of some 'vaccine preparation') and ('has function' some ('vaccine function' and ('is realized by' only ('vaccine immunization' and (realizes some ('vaccine host role' and (role_of some 'organism' and has_disposition some disease)))))))). The domain of this relation is a vaccine. The range of this relation is a disease.""" ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; obo:IAO_0000118 "immunization against disease", "vaccine immunization against disease" ; a owl:ObjectProperty ; rdfs:domain obo:VO_0000001 ; rdfs:label "immunizes against disease" ; rdfs:range obo:DOID_4 . obo:VO_0001012 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "classical swine fever virus vaccine" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11096 ] . obo:VO_0001013 obo:IAO_0000115 "A Measles-Mumps-Rubella vaccine that is manufactured by Sanofi Aventis." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Morupar" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:CHEBI_52071 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003026 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001014 obo:IAO_0000115 "a live attenuated quality of a bacterial vaccine strain. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "bacterial vaccine organism live attenuated" ; rdfs:subClassOf obo:VO_0000173, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:NCBITaxon_2 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000173 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:NCBITaxon_2 ] ) ] . obo:VO_0001015 obo:IAO_0000115 "a live attenuated quality of a virus vaccine strain. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "viral vaccine organism live attenuated" ; rdfs:subClassOf obo:VO_0000173, [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:NCBITaxon_10239 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000173 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:NCBITaxon_10239 ] ) ] . obo:VO_0001016 obo:IAO_0000116 "Fowlpox virus vectored" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vectormune FP-ND" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001017 obo:IAO_0000115 "A live attenuated vaccine that protects against Marek's disease virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Marek's; disease virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated Marek's disease virus vaccine" ; rdfs:subClassOf obo:VO_0001220, obo:VO_0012162, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] . obo:VO_0001018 obo:IAO_0000115 "A live attenuated viral vaccine that protects aganist Newcastle disease virus infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated Newcastle disease virus vaccine" ; rdfs:subClassOf obo:VO_0001220, obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0001222 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ) ] . obo:VO_0001019 obo:IAO_0000115 "an avian reovirus vaccine that using live attenauted reovirus. " ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated avian reovirus vaccine" ; rdfs:subClassOf obo:VO_0001220, obo:VO_0001513, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0001513 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ) ] . obo:VO_0001020 obo:IAO_0000116 "Sporulated oocysts of several or all of the avian species" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Advent" ; rdfs:subClassOf obo:VO_0000906, obo:VO_0001459, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001021 obo:IAO_0000115 "a feline panleukopenia virus vaccine where the virus used is live attenuated. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated feline panleukopenia virus vaccine" ; rdfs:subClassOf obo:VO_0000389, obo:VO_0001220, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000389 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ) ] . obo:VO_0001022 obo:IAO_0000115 "Megan Vac1 is a Salmoneela vaccine that consists of a double gene-deleted S. enterica serovar Typhimurium strain and is designed for protection of broilers to reduce Salmonella contamination." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.fda.gov/ohrms/dockets/dockets/00n0504/00N-0504_emc-001650-02.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Megan Vac1" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001023 obo:IAO_0000115 "a bacterial vaccine vector that uses TB vaccine BCG as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "BCG vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 33892" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001024 obo:IAO_0000115 "an avian influenza vaccine that uses inactivated viral organism" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "inactivated avian influenza vaccine" ; rdfs:subClassOf obo:VO_0000461, obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000461 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ) ] . obo:VO_0001025 obo:IAO_0000115 "a viral vaccine vector that uses a vesicular stomatitis virus (VSV) as the vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vesicular stomatitis virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11276" ; rdfs:subClassOf obo:VO_0001121 . obo:VO_0001026 obo:IAO_0000116 "Killed oral vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AquaVac Furuvac" ; rdfs:subClassOf obo:VO_0000820, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8015 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001174 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001027 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Lohman Animal Health International" . obo:VO_0001028 obo:IAO_0000115 "a parasite vaccine vector using a live attenuated Leishmania tarentolae strain. " ; obo:IAO_0000117 "Yongqun He, Carly Mantin" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Leishmania tarentolae vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 5689" ; rdfs:subClassOf obo:VO_0001034 . obo:VO_0001029 obo:IAO_0000119 "PubMed:23969885" ; a owl:Class ; rdfs:label "autologous dendritic cell melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0001030 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced mouse immune response" ; rdfs:subClassOf obo:VO_0000287, [ a owl:Restriction ; owl:onProperty obo:OBI_0000293 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_10090 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000725 ] ) ] ] . obo:VO_0001031 obo:IAO_0000112 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/21907709" ; obo:IAO_0000115 "a bacterial vaccine vector using a live attenuated Salmonella enterica strain SL3261. " ; obo:IAO_0000117 "Yongqun He, Carly Mantin" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Salmonella typhimurium SL3261 vaccine vector" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001032 obo:IAO_0000112 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/21964456" ; obo:IAO_0000115 "a bacterial vaccine vector using a live attenuated Edwardsiella tarda strain EIB202" ; obo:IAO_0000117 "Yongqun He, Carly Mantin" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Edwardsiella tarda EIB202 vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 498217" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001033 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Babesia bigemina vaccine" ; rdfs:subClassOf obo:VO_0003047, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5866 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5866 ] . obo:VO_0001034 obo:IAO_0000115 "a vaccine vector that uses a parasite as the vector." ; obo:IAO_0000117 "Yongqun He, Carly Martin" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "parasite vaccine vector" ; rdfs:subClassOf obo:VO_0000599 . obo:VO_0001035 obo:IAO_0000115 "a bacterial vaccine against Yersinia ruckeri infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yersinia ruckeri vaccine" ; rdfs:subClassOf obo:VO_0000601, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29486 ] . obo:VO_0001036 obo:IAO_0000112 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/23403993" ; obo:IAO_0000115 "a bacterial vaccine vector using a live attenuated Streptococcus gordonii vaccine vector." ; obo:IAO_0000117 "Yongqun He, Carly Mantin" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Streptococcus gordonii vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 1302" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001037 obo:IAO_0000112 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/16823926" ; obo:IAO_0000115 "a bacterial vaccine vector using a live attenuated Bordetella pertussis BPZE as a vaccine vector." ; obo:IAO_0000117 "Yongqun He, Carly Mantin" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Bordetella pertussis BPZE vaccine vector" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001038 obo:IAO_0000112 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/9767712" ; obo:IAO_0000115 "a bacterial vaccine vector using the HS93Tox- mutant of the serovar 7 strain of Actinobacillus pleuropneumoniae. This mutant lacks the genes encoding the toxin ApxA and the post-translational activating protein ApxC, but still has genes required for secretion, making it a good vector. " ; obo:IAO_0000117 "Yongqun He, Carly Mantin" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Actinobacillus pleuropneumoniae HS93Tox vaccine vector" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001039 obo:IAO_0000115 "An object property that represents an organism has a mutation of a specific gene from the organism genome." ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has gene mutation" . obo:VO_0001040 obo:IAO_0000115 "an Avipox virus vaccine vector that uses a fowlpox virus as the vector" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "fowlpox virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10261", "pmid: 10729156" ; rdfs:subClassOf obo:VO_0001143 . obo:VO_0001041 obo:IAO_0000115 """A Listeria monocytogenes vaccine vector that uses the highly attenuated LM1-2 strain """ ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 23027427 " ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "L. monocytogenes LM1-2 vaccine vector" ; rdfs:subClassOf obo:VO_0000068 . obo:VO_0001042 obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "BHV-4 vaccine vector", "bovine herpesvirus 4 vaccine vector" ; obo:IAO_0000119 "PMID: 23830977; PMID: 23300989; PMID: 21320537; PMID: 24752229" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "BoHV-4 vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10385" ; rdfs:subClassOf obo:VO_0000283 . obo:VO_0001043 obo:IAO_0000115 "an Avipox virus vaccine vector that uses an attenuated canarypox virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "Poulet et al. 2007, PubMed PMID: 17227690.", "WEB: http://en.wikipedia.org/wiki/Canarypox" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "canarypox vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 44088" ; rdfs:subClassOf obo:VO_0001143 . obo:VO_0001044 obo:IAO_0000115 "a bacterial vaccine vector that uses an attenuated Vibrio cholerae strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 9529093" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Vibrio cholerae vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 666" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001045 obo:IAO_0000115 "a viral vaccine vector that uses an avian paramyxovirus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "avian paramyxovirus type 3 vaccine vector" ; obo:IAO_0000119 "PMID: 21525340" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "APMV-3 vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 207246" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001046 obo:IAO_0000115 "a herpesvirus vaccine vector that uses a herpes simplex virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "HSV vaccine vector" ; obo:IAO_0000119 "PMID: 22713696; PMID: 19428888; PMID: 20835362; PMID: 16996101" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Herpes simplex virus vaccine vector" ; rdfs:subClassOf obo:VO_0000283 . obo:VO_0001047 obo:IAO_0000115 "an adenovirus vaccine vector that uses the simian adenovirus ChAd63 strain." ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 22275401; PMID: 23526949; PMID: 22363582" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "simian adenovirus ChAd63 vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 413684" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001048 obo:IAO_0000115 "an orthopoxvirus vaccine vector that uses an attenuated Raccoon poxvirus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 22921740" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "raccoon poxvirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10256" ; rdfs:subClassOf obo:VO_0001146 . obo:VO_0001049 obo:IAO_0000116 "Live temperature-sensitive mutant strain; eye drop administration" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaxsafe MS" ; rdfs:subClassOf obo:VO_0001077, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000861 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001050 obo:IAO_0000115 "A herpesevirus vaccine vector that uses an established live-virus vaccine against Aujeszky's disease of swine, pseudorabies virus (PrV) strain Bartha (PrV-Ba), to serve as vector." ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "PrV vaccine vector ", "Suid herpesvirus 1 strain Bartha vaccine vector" ; obo:IAO_0000119 "PMID: 24431235" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pseudorabies virus strain Bartha vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 1006205" ; rdfs:subClassOf obo:VO_0000283 . obo:VO_0001051 obo:IAO_0000115 "an adenovirus vaccine vector that uses a porcine adenovirus 3 strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "PAV3 vaccine vector" ; obo:IAO_0000119 "PMID: 11402666; PMID: 21179494; PMID: 10091994; PMID: 12954206; PMID: 17565687" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "porcine adenovirus 3 vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 35265" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001052 obo:IAO_0000115 "a viral vaccine vector that uses a poliovirus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "PV vaccine vector" ; obo:IAO_0000119 "PMID: 19003009; PMID: 12423772; PMID: 17196342" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "poliovirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 138950" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001053 obo:IAO_0000116 "In vitro-cultured supernatant antigens, reduce clinical disease" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Nobivac Piro" ; rdfs:subClassOf obo:VO_0001074, obo:VO_0002792, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9615 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001054 obo:IAO_0000116 "Live submucosal vaccine; deletions in aroA gene" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equilis StrepE" ; rdfs:subClassOf obo:VO_0000948, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001055 obo:IAO_0000115 "an adenovirus vaccine vector that uses a chimpanzee adenovirus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "chimpanzee adenovirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 310542" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001056 obo:IAO_0000115 "a viral vaccine vector that uses a measles virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "MV vaccine vector" ; obo:IAO_0000119 "PMID: 24084235; PMID: 24606680; PMID: 23642239; PMID: 23550539; PMID: 23516477" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "measles virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11234" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001057 obo:IAO_0000115 "a viral vaccine vector that uses a Coxsackievirus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 20824074; PMID: 11115722; PMID: 19053211; PMID: 20088713; PMID: 21389776; PMID: 19941986; PMID: 11160741" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Coxsackievirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 12066" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001058 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Centre for Ticks and Tickborne Disease, Malawi" . obo:VO_0001059 obo:IAO_0000115 "a poxvirus vaccine vector that uses an attenuated Oka varicella virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "Human herpesvirus 3 strain Oka vaccine vaccine" ; obo:IAO_0000119 "PMID: 10720546; PMID: 16615495; PMID: 18053621" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Oka varicella vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 341980" ; rdfs:subClassOf obo:VO_0000283 . obo:VO_0001060 obo:IAO_0000115 "a viral vaccine vector that uses a NewCastle virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "NDV vaccine vector " ; obo:IAO_0000119 "PMID: 23845804" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Newcastle disease virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11176" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001061 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Theileria parva vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5875 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5875 ] . obo:VO_0001062 obo:IAO_0000115 "a viral vaccine vector that uses a myxoma virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 10627521; PMID: 12951040; PMID: 14972520; PMID: 8719525; PMID: 12057600; PMID: 18474552; PMID: 21835800; PMID: 22244980" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "myxoma virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10273" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001063 obo:IAO_0000115 "a viral vaccine vector that uses a Maraba virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 24322333" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Maraba virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 1046251" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001064 obo:IAO_0000115 "a bacterial vaccine vector that uses an attenuated Mycobacterium smegmatis strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 22546648; PMID: 21900527" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Mycobacterium smegmatis vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 1772" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001065 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neospora caninum vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] . obo:VO_0001066 obo:IAO_0000115 "a bacterial vaccine vector that uses an attenuated Lactobacillus gasseri strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 21375708; PMID: 20722604; PMID: 21900526" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Lactobacillus gasseri vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 1596" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001067 obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "HVT vaccine vector", "Meleagrid herpesvirus 1 vaccine vector" ; obo:IAO_0000119 "PMID: 22845318" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "herpesvirus of turkey vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 37108" ; rdfs:subClassOf obo:VO_0000283 . obo:VO_0001068 obo:IAO_0000115 "A Herpes simplex virus vaccine vector that uses a virus type 1 strain " ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "HSV-1 vaccine vector" ; obo:IAO_0000119 "PMID: 19428888" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Herpes simplex virus vaccine 1 vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10298" ; rdfs:subClassOf obo:VO_0001046 . obo:VO_0001069 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "ImmunoVaccine Technologies, Canada" . obo:VO_0001070 obo:IAO_0000115 "a bacterial vaccine vector that uses an E. coli strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 24746937" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "E. coli vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 562" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001071 obo:IAO_0000116 "Killed oral vaccine", "Reference: http://www.spaquaculture.com/default.aspx?pageid=553" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AquaVac Vibrio" ; rdfs:subClassOf obo:VO_0000823, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_13489 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8015 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001174 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001072 obo:IAO_0000115 "a viral vaccine vector that uses a duck enteritis virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "Anatid herpesvirus 1 vaccine vector" ; obo:IAO_0000119 "PMID: 23267833" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "duck enteritis virus vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 104388" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001073 obo:IAO_0000115 "a herpesvirus vaccine vector that uses a CMV virus strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "Cytomegalovirus vaccine vector" ; obo:IAO_0000119 "PMID: 23811402" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "CMV vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10358" ; rdfs:subClassOf obo:VO_0000283 . obo:VO_0001074 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Babesia canis vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5867 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5867 ] . obo:VO_0001075 obo:IAO_0000115 "a bacterial vaccine vector that uses a Salmonella typhi strain" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Salmonella typhi vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 90370" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001076 obo:IAO_0000115 "a recombinant vector vaccine that uses a homologous vector, i.e., when the target species of the vaccine is a natural host for the vector." ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000119 "WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant homologous vector vaccine" ; rdfs:subClassOf obo:VO_0000484 . obo:VO_0001077 obo:IAO_0000115 "a bacterial vaccine against Mycoplasma synoviae infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycoplasma synoviae vaccine" ; rdfs:subClassOf obo:VO_0000604, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2109 ] . obo:VO_0001078 obo:IAO_0000115 "a recombinant vector vaccine that uses a homologous vector, i.e., when the target species of the vaccine is not one of the natural hosts for the vector." ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000119 "WEB: http://www.biosafety.be/GT/Regulatory/Veterinary_vaccines/EMEA_000404en.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant heterologous vector vaccine" ; rdfs:subClassOf obo:VO_0000484 . obo:VO_0001079 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Local veterinary institutes" . obo:VO_0001080 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "Androstenedione" ; rdfs:subClassOf obo:FMA_12278 . obo:VO_0001081 obo:IAO_0000115 "an adenovirus vaccine vector that uses an Adenovirus serotype 5 strain." ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000118 "human adenovirus 5 vaccine vector" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "adenovirus serotype 5 vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 28285" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001082 obo:IAO_0000115 "an adenovirus vaccine vector that contains a deletion of the gp64 gene. As a result of the deletion, this vector is unable to propagate infection from cell to cell, and this defect results from both a severe reduction in the production of budded virions and the absence of GP64 on virions. " ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000119 "PMID: 17989172" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "AcMNPV vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 46015" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001083 obo:IAO_0000115 "protozoan vaccine that is used to protect against Giardia intestinalis infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Giardia duodenalis vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5741 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5741 ] . obo:VO_0001084 obo:IAO_0000115 "a viral vaccine vector that uses a baculovirus as the vector " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 22705893" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "baculovirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10469" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001085 obo:IAO_0000115 "a Chlamydia bacterial vaccine against C. abortus infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamydophila abortus vaccine" ; rdfs:subClassOf obo:VO_0000573, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83555 ] . obo:VO_0001086 obo:IAO_0000115 "an adenovirus vaccine vector that uses a complex adenovirus as the vector strain." ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000118 "CAdVax vaccine vector" ; obo:IAO_0000119 "PMID: 19776190; PMID: 18480438; PMID: 17634508; PMID: 18216185; PMID: 16501083" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "complex adenovirus vaccine vector" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001087 obo:IAO_0000115 "an adenovirus vaccine vector that uses a human adenovirus as the vector strain." ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000118 "HAd vaccine vector" ; obo:IAO_0000119 "PMID: 16297508; PMID: 15761255" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "human adenovirus vaccine vector" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001088 obo:IAO_0000115 "a viral vaccine vector that uses a murine leukemia virus as the vaccine vector" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Murine_leukemia_virus" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "murine leukemia viral vector vaccine" ; rdfs:seeAlso "NCBI Taxonomy ID: 11786" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001089 obo:IAO_0000117 "YH, XZ" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "CDC recommendation of the use of Influenza A (h1N1) 2009 vaccine" ; rdfs:subClassOf obo:IAO_0000001 . obo:VO_0001090 obo:IAO_0000115 "a population group that have priority for vaccination when a vaccine is first available." ; obo:IAO_0000117 "YH, XZ" ; obo:IAO_0000118 "vaccination target group" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "vaccinee priority group" ; rdfs:subClassOf obo:VO_0000546 . obo:VO_0001091 obo:IAO_0000116 "Chimera H5N3 virus, inactivated in oil-based adjuvant" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Poulvac FluFend I AI H5N3 RG" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000205 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001092 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "United States Department of Agriculture"@en ; a obo:OBI_0000450, owl:NamedIndividual ; rdfs:label "USDA" . obo:VO_0001093 obo:IAO_0000115 "a vaccinia vaccine vector that uses the highly attenuated NYVAC as vector" ; obo:IAO_0000116 "A highly attenuated vaccinia virus strain, NYVAC (vP866), was derived from a plaque-cloned isolate of the Copenhagen vaccine strain by the precise deletion of 18 open reading frames (ORFs) from the viral genome. Source: http://www.ncbi.nlm.nih.gov/pubmed/1566575" ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000119 "PMID: 22930439;; PMID: 24069354; PMID: 1566575" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "NYVAC vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10249 (for Vaccinia virus Copenhagen)" ; rdfs:subClassOf obo:VO_0000600 . obo:VO_0001094 obo:IAO_0000117 "XY, XZ" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "pregnant women" ; rdfs:subClassOf obo:OBI_0000181 . obo:VO_0001095 obo:IAO_0000115 "passive immunization by injecting a recipient with pre-made antibody, antitoxin, epitope, etc." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "passive immunization by injecting pre-made immune element" ; rdfs:subClassOf obo:VO_0000492 . obo:VO_0001096 obo:IAO_0000115 "A vaccine used to increase the fecundity in breeding ewes. Ovastim increases the number of multiple ovulations and therefore the number of multiple births." ; obo:IAO_0000116 "Increased ovulation/twinning" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.virbac.co.nz/p-virbacnzpuben/display.aspx?srv=p-virbacnz&typ=pub&lang=en&cmd=view&style=styles/specie.xsl&select=PRODUCT[@ID$eq$PRODUCT_264]&affp=&" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ovastim" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000372, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001080 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000914 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001097 obo:IAO_0000116 "Canarypox virus-vectored vaccine (HA and F antigens)" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RECOMBITEK rDistemper" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9615 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001098 obo:IAO_0000117 "XY, XZ" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "persons living with or providing care for infants aged <6 months" ; rdfs:subClassOf obo:OBI_0000181 . obo:VO_0001099 obo:IAO_0000117 "XY, XZ" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "health-care and emergency medical services personnel" ; rdfs:subClassOf obo:OBI_0000181 . obo:VO_0001100 obo:IAO_0000117 "XY, XZ" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "persons aged 6 months--24 years" ; rdfs:subClassOf obo:OBI_0000181 . obo:VO_0001101 obo:IAO_0000117 "XY, XZ" ; obo:IAO_0000119 "WEB: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr58e0821a1.htm" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "persons aged 25--64 years with medical conditions at higher risk for influenza-related complications" ; rdfs:subClassOf obo:OBI_0000181 . obo:VO_0001102 obo:IAO_0000115 "a viral vaccine vector that uses a retroviral strain" ; obo:IAO_0000117 "Yongqun He" ; obo:IAO_0000119 "PMID: 2839718" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "retroviral vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11632", "Vaxvec: 23" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001103 obo:IAO_0000115 "inactivation is a processual entity that produces inactive material." ; obo:IAO_0000117 "YH, MC, XZ" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "inactivation" ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0001104 obo:IAO_0000117 "Yongqun He", "a retroviral vaccine vector where a Rous sarcoma virus (a retrovirus) is used" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Rous sarcoma virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11886", "Vaxvec: 20" ; rdfs:subClassOf obo:VO_0001102 . obo:VO_0001105 obo:IAO_0000115 "a bacterial vaccine against Lawsonia intracellularis infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lawsonia intracellularis vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29546 ] . obo:VO_0001106 obo:IAO_0000115 "a poxvirus vaccine vector that uses a swinepox virus as the vector" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "swinepox virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10276", "PMID: 22515033; PMID: 21807055; PMID: 22884664; PMID: 23135159" ; rdfs:subClassOf obo:VO_0000447 . obo:VO_0001107 obo:IAO_0000115 "a vaccinia virus vector that uses the Modified Vaccinia Ankara (MVA) virus. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 24933081" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Modified Vaccinia Ankara (MVA) virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 467144" ; rdfs:subClassOf obo:VO_0000600 . obo:VO_0001108 obo:IAO_0000115 "a poxvirus vaccine vector that uses an ORF virus which is a parapoxvirus." ; obo:IAO_0000117 "Shunzhou Deng, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "ORF virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10258" ; rdfs:subClassOf obo:VO_0000447 . obo:VO_0001109 obo:IAO_0000115 "a vaccinia virus vector that uses the MVTT vaccine strain as the vector. MVTT is an attenuated vaccine strain. " ; obo:IAO_0000117 "Shunzhou Deng, Yongqun He" ; obo:IAO_0000118 "vaccinia virus TianTan vaccine vector" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "MVTT vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10253" ; rdfs:subClassOf obo:VO_0000600 . obo:VO_0001110 obo:IAO_0000115 "a fertility vaccine that enhance fertility in sheep." ; obo:IAO_0000116 "Linked to human serum albumin; increased ovulation/twinning", "withdrawn" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.journals.elsevierhealth.com/periodicals/anirep/article/PII0378432093901125/abstract" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fecundin" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000372, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001080 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001212 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001111 obo:IAO_0000115 "A poxvirus vaccine vector that uses an attenuated lumpy skin disease virus as the vector. " ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "LSDV vaccine vector" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "lumpy skin disease virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 59509" ; rdfs:subClassOf obo:VO_0001115 . obo:VO_0001112 obo:IAO_0000115 "a viral vaccine vector that uses a bovine parainfluenza virus strain as vector" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000119 "PMID: 22570186; PMID: 24478424." ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "bovine parainfluenza virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11215" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001113 obo:IAO_0000116 "Gametocyte antigen(s); transmission blocking through maternal antibody transfer" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CoxAbic" ; rdfs:subClassOf obo:VO_0001125, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000964 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001114 obo:IAO_0000115 "a Bordetella bacterial vaccine against infection of B. avium" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella avium vaccine" ; rdfs:subClassOf obo:VO_0000587, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_521 ] . obo:VO_0001115 obo:IAO_0000115 "a poxvirus vaccine vector that uses an attenuated capripoxvirus strain as the vaccine vector" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "capripoxvirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10265" ; rdfs:subClassOf obo:VO_0000447 . obo:VO_0001116 obo:IAO_0000115 "survival of live vaccine inside host is a processual entity that represents the survival of a live vaccine inside its host. The time of the survival is often important for the success of the live vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "survival of live vaccine inside host" ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0001117 obo:IAO_0000115 "persistence of vaccine induced immune response is a processual entity that indicates the persistence of an immune reponse induced by a vaccine in a vaccinated host." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "persistence of vaccine induced immune response" ; rdfs:subClassOf obo:BFO_0000015 . obo:VO_0001118 obo:IAO_0000115 "a bacterial vaccine vector that uses a Corynebacterium pseudotuberculosis strain as the vaccine vector" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Corynebacterium pseudotuberculosis vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 1719" ; rdfs:subClassOf obo:VO_0000166 . obo:VO_0001119 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Merial, Inc" . obo:VO_0001120 obo:IAO_0000116 "Killed tachyzoites, reduces abortion" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovilis Neoguard" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001121 obo:IAO_0000115 "a viral vaccine vector that uses a rhabdovirus-based viral strain as the vaccine vector" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "rhabdovirus-based vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11270" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0001122 obo:IAO_0000115 "a recombinant vaccine vector that uses Saccharomyces cerevisiae as the vaccine vector" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Saccharomyces cerevisiae vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 4932" ; rdfs:subClassOf obo:VO_0001141 . obo:VO_0001123 obo:IAO_0000116 "Modified live virus" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RECOMBITEK Canine Parvo" ; rdfs:subClassOf obo:VO_0012180, [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001124 obo:IAO_0000115 "a viral vaccine vector that uses a Venezuelan equine encephalitis virus strain as the vaccine vector" ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "Venezuelan equine encephalitis virus vaccine vector" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "VEE vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 11036" ; rdfs:subClassOf obo:VO_0000144 . obo:VO_0001125 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Eimeria maxima vaccine" ; rdfs:subClassOf obo:VO_0000906, obo:VO_0001459, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5804 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000906 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5804 ] ) ] . obo:VO_0001126 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm192126.htm" ; obo:VO_0003099 "Agriflu" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003160 "Active immunization of adults 18 years of age and older against influenza disease caused by influenza virus subtypes A and type B present in the vaccine." ; obo:VO_0003162 "BL 125297/32" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Agriflu" ; rdfs:seeAlso "CVX: 140" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000971 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001127 obo:IAO_0000115 "live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated Brucella vaccine" ; rdfs:seeAlso "CVX: 135" ; rdfs:subClassOf obo:VO_0000025, obo:VO_0001217, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000025 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ) ] . obo:VO_0001128 obo:IAO_0000115 "a canarypox vaccine vector that uses an attenuated canarypox virus strain ALVAC. The ALVAC vector is a canarypox virus clone obtained after four rounds of plaque purification of a strain from a vaccine for canaries. " ; obo:IAO_0000117 "Yongqun He, Shunzhou Deng" ; obo:IAO_0000118 "ALVAC" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/17227690" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "ALVAC vaccine vector" ; rdfs:subClassOf obo:VO_0001043 . obo:VO_0001129 obo:IAO_0000115 "an adenovirus vaccine vector that is not able to replicate." ; obo:IAO_0000117 "Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "non-replicating adenovirus accine vector" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001130 obo:IAO_0000115 "a bacterial vaccine against A. pleuropneumoniae infection" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Actinobacillus pleuropneumoniae vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_715 ] . obo:VO_0001131 obo:IAO_0000115 "an adenovirus vaccine vector that is able to replicate." ; obo:IAO_0000117 "Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "replicating adenovirus accine vector" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0001132 obo:IAO_0000115 "assay of CFU reduction in liver is a CFU reduction assay that is measured using the extracted liver as the tissue for isolation of infected pathogens." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "assay of CFU reduction in liver" ; rdfs:subClassOf obo:VO_0000242 . obo:VO_0001133 obo:IAO_0000115 "assay of CFU reduction in lung is a CFU reduction assay that is measured using the extracted lung as the tissue for isolation of infected pathogens." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "assay of CFU reduction in lung" ; rdfs:subClassOf obo:VO_0000242 . obo:VO_0001134 obo:IAO_0000115 "live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella abortus infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated Brucella abortus vaccine" ; rdfs:subClassOf obo:VO_0000108, obo:VO_0001127, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000108 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ) ] . obo:VO_0001135 obo:IAO_0000115 "live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella melitensis infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated Brucella melitensis vaccine" ; rdfs:subClassOf obo:VO_0000709, obo:VO_0001127, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000709 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ) ] . obo:VO_0001136 obo:IAO_0000115 "live attenuated Brucella vaccine is a live attenuated vaccine that protects against a Brucella suis infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated Brucella suis vaccine" ; rdfs:subClassOf obo:VO_0000721, obo:VO_0001127, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000721 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ) ] . obo:VO_0001137 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Eimeria tenella vaccine" ; rdfs:subClassOf obo:VO_0000906, obo:VO_0001459, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5802 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000906 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5802 ] ) ] . obo:VO_0001138 obo:IAO_0000116 "S48 strain with a lost ability to form cysts after passages in mice" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ovilis Toxovax" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001139 obo:IAO_0000115 "vaccine viability is a viability of a vaccine organism." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccine organism viability" ; rdfs:subClassOf obo:PATO_0000169 . obo:VO_0001140 obo:IAO_0000116 "DNA vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "West Nile-Innovator DNA" ; rdfs:subClassOf obo:VO_0000752, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000205 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001141 obo:IAO_0000115 "a recombinant vaccine vector that uses a fungus as the vaccine vector" ; obo:IAO_0000117 "Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "fungal vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 4751" ; rdfs:subClassOf obo:VO_0000599 . obo:VO_0001142 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leishmania donovani vaccine" ; rdfs:subClassOf obo:VO_0000762, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000762 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] ) ] . obo:VO_0001143 obo:IAO_0000115 "a poxvirus vaccine vector that uses an avipox virus as the vector" ; obo:IAO_0000117 "Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Avipox virus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10260" ; rdfs:subClassOf obo:VO_0000447 . obo:VO_0001144 obo:IAO_0000117 "YH" ; obo:IAO_0000118 "pCIBLSOmp31" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella DNA vaccine encoding chimera BLSOmp31" ; rdfs:seeAlso "PMID: 17600596" ; rdfs:subClassOf obo:VO_0001226 . obo:VO_0001145 obo:IAO_0000115 "vaccine being viable is a vaccine viability that indicates a vaccine uses live organism." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccine organism live" ; rdfs:subClassOf obo:VO_0001139 . obo:VO_0001146 obo:IAO_0000115 "a poxvirus vaccine vector that uses an orthopox virus as the vector" ; obo:IAO_0000117 "Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Orthopoxvirus vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 10242" ; rdfs:subClassOf obo:VO_0000447 . obo:VO_0001147 obo:IAO_0000115 "A cytokine vaccine adjuvant that contains IL-12." ; obo:IAO_0000117 "Allen Xiang", "Oliver He" ; a owl:Class ; rdfs:label "IL-12 vacince adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001148 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "no vaccine protection" ; rdfs:subClassOf obo:VO_0000247 . obo:VO_0001149 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "significant vaccine protection" ; rdfs:subClassOf obo:VO_0000247 . obo:VO_0001150 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "enhanced significant protection" ; rdfs:subClassOf obo:VO_0000247 . obo:VO_0001151 obo:IAO_0000115 "bacterial vaccine that is used to protect against Piscirickettsia salmonis infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Piscirickettsia salmonis vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1238 ] . obo:VO_0001152 obo:IAO_0000115 "An E. coli vaccine against enterotoxigenic E. coli infections" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "ETEC vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "enterotoxigenic E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0001153 obo:IAO_0000116 "Increased ovulation/twinning" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Androvax" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000372, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001080 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001154 obo:IAO_0000115 "B. abortus L7/L12 is a B. abortus subunit vaccine using L7/L12 that is formed by recombinant Human Serum Albumin (HAS)-L7/L12 fusion protein." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "Brucella abortus Human serum albumin (HAS)-L7/L12" ; obo:IAO_0000119 "PMID: 19293473" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. abortus HSA-L7/L12" ; rdfs:subClassOf obo:VO_0000323 . obo:VO_0001155 obo:IAO_0000115 "An E. coli vaccine against Shiga toxin-producing E. coli (STEC) infections" ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "STEC vaccine" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238053/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shiga toxin-producing E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0001156 obo:IAO_0000115 "a vaccine against avian pathogenic Escherichia coli (APEC) infection, a major problem for the poultry industry in the world." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "APEC vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian pathogenic E. coli vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0001157 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "an E. coli vaccine against O157 E. coli strain infections" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli O157 vaccine" ; rdfs:subClassOf obo:VO_0000041 . obo:VO_0001158 obo:IAO_0000116 "Extracted ApxI, ApxII, ApxIII, and outer membrane proteins" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcilis APP" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001159 obo:IAO_0000115 "PUREVAX Ferret Distemper is a lyophilized ferret vaccine of a recombinant canarypox vector expressing the HA and F glycoproteins of canine distemper virus. Reference: http://www.drugs.com/vet/purevax-ferret-distemper.html." ; obo:IAO_0000116 "Canarypox virus-vectored vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PUREVAX Ferret Distemper" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9669 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001160 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "vaccination dose specification" ; rdfs:subClassOf obo:OBI_0000969, [ a owl:Restriction ; owl:onProperty obo:IAO_0000136 ; owl:someValuesFrom obo:VO_0000002 ] . obo:VO_0001161 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "challenge dose specification" ; rdfs:subClassOf obo:OBI_0000969, [ a owl:Restriction ; owl:onProperty obo:IAO_0000136 ; owl:someValuesFrom obo:OBI_0000712 ] . obo:VO_0001162 obo:IAO_0000115 "specification of time interval after vaccination for challenge is a plan specification that specifies the time interval after vacciation for challenge" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "specification of vaccination-challenge interval" ; rdfs:subClassOf obo:IAO_0000104 . obo:VO_0001163 obo:IAO_0000115 "pathogen challenge protocol is a protocol that is used for a pathogen challenge process." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "pathogen challenge protocol" ; rdfs:subClassOf obo:OBI_0000272 . obo:VO_0001164 obo:IAO_0000115 "A titer measurement of viable bacterial or fungal numbers. It equals to a reduction of a CFU count from another CFU count. This term is often used as a measurement of a vaccine protection study." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "reduction of colony forming unit" ; rdfs:subClassOf obo:VO_0000555 . obo:VO_0001165 obo:IAO_0000115 "intraperitoneal pathogen challenge is a pathogen challenge process that occurs in the intraperitoneal site of a host." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "intraperitoneal pathogen challenge" ; rdfs:subClassOf obo:OBI_0000712 . obo:VO_0001166 obo:IAO_0000115 "a vaccination process that occurs in the intraperitoneal route" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "intraperitoneal vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000344 ] . obo:VO_0001167 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "KLH-s-FimH1-25 with CFA and then IFA" ; rdfs:seeAlso "VIOLIN Vaccine ID: 4329" ; rdfs:subClassOf obo:VO_0000628 . obo:VO_0001168 obo:IAO_0000115 "an E. coli subunit vaccine that uses E. coli FimH adhesin protein as teh antigen, and uses the complete Freund's adjuvant (CFA) in the first vaccination and the incomplete Freund's adjuvant (IFA) in the boost vaccination." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PubMed: http://www.ncbi.nlm.nih.gov/pubmed/9110982" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli FimH with CFA and then IFA" ; rdfs:seeAlso "VIOLIN Vaccine ID: 4330" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010987 ] . obo:VO_0001169 obo:IAO_0000115 "E. coli DNA vaccine is a DNA vaccine that protects against an E. coli infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli DNA vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000041, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000041 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ] ) ] . obo:VO_0001170 obo:IAO_0000115 "a vaccine organism that is a specific strain" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "vaccine strain" ; rdfs:subClassOf obo:VO_0000506, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001182 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001182 ] . obo:VO_0001171 obo:IAO_0000115 "B. melitensis bp26 and omp31 deletion vaccine is a Brucella melitensis vaccine that has double deletions of bp26 and omp31." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "CGV2631" ; obo:IAO_0000119 "PMID: 17070627" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis Rev. 1 with bp26 and omp31 deletions" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_29459 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:VO_0002561 obo:VO_0002567 ) ] ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ] . obo:VO_0001172 obo:IAO_0000115 "pCIOmp31 is a B. melitensis DNA vaccine expressing Omp31 that uses the pCI plasmid." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 16177328" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pCIOmp31" ; rdfs:subClassOf obo:VO_0000325 . obo:VO_0001173 obo:IAO_0000115 "pTargeTomp31 is a B. melitensis DNA vaccine expressing Omp31 that uses the pTargeT mammalian expression system vector (Promega, USA)." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 17014873" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pTargeTomp31" ; rdfs:subClassOf obo:VO_0000325 . obo:VO_0001174 obo:IAO_0000116 "Intervet has merged with Schering-Plough Animal Health and become Intervet/Schering-Plough Animal Health‚Ñ¢ (YL.)" ; obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Schering-Plough Animal Health" . obo:VO_0001175 obo:IAO_0000115 "B. abortus L7/L12 fused to MBP is a B. abortus subunit vaccine using L7/L12 that uses recombinant L7/L12 fused on maltose binding protein MBP." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "PMID: 8873388" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. abortus L7/L12 fused to MBP" ; rdfs:subClassOf obo:VO_0000323 . obo:VO_0001176 obo:IAO_0000115 "inactivated influenza vaccine is an inactivated viral vaccine that targets at influenza viral infections." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "inactivated influenza vaccine" ; rdfs:subClassOf obo:VO_0000642, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000642 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ) ] . obo:VO_0001177 obo:IAO_0000116 "Precocious and egg-passaged lines" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Livacox" ; rdfs:subClassOf obo:VO_0001137, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000846 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001178 obo:IAO_0000115 "live attenuated influenza vaccine is a live attenuated vaccine that protects against influenza viral infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated influenza vaccine" ; rdfs:subClassOf obo:VO_0000642, obo:VO_0001220, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000642 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ) ] . obo:VO_0001179 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Bayer Leverkusen" . obo:VO_0001180 oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "laboratory test" ; rdfs:subClassOf obo:OBI_0000011 . obo:VO_0001181 obo:IAO_0000116 "Live temperature-sensitive mutant strain; eye drop administration" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaxsafe MG" ; rdfs:subClassOf obo:VO_0000949, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000861 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001182 obo:IAO_0000115 "a vaccine role that is borne by an organism strain serving as a vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine strain role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0001183 obo:IAO_0000116 "Peptide conjugated to keyhole limpet hemocyanin in mycobacterium-oil adjuvant (AdjuVac); contraceptive vaccine to control wildlife", "registration reported to be in progress" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.aphis.usda.gov/wildlife_damage/nwrc/research/reproductive_control/gonacon.shtml", "a contraceptive vaccine that is used in wildlife population" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GonaCon" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000759, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000972 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9850 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9900 ] . obo:VO_0001184 oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine protection ANOVA" ; rdfs:subClassOf obo:OBI_0200201 . obo:VO_0001185 obo:IAO_0000116 "In ovo delivery using proprietary platform injection system" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Inovocox" ; rdfs:subClassOf obo:VO_0000906, obo:VO_0001459, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000959 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001186 obo:IAO_0000115 "A data set that represents a set of data for a list of variables (e.g., vaccination dose) for the data analysis of an vaccine investigation study." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccine investigation data set" ; rdfs:subClassOf obo:IAO_0000100, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001188 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001189 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001190 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001191 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001192 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001193 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001194 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001195 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001196 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001197 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001198 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001199 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001202 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001203 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001204 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001205 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001206 ] . obo:VO_0001187 obo:IAO_0000115 "a vaccination that occurs in the intramuscular route." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "intramuscular vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000340 ] . obo:VO_0001188 obo:IAO_0000115 "A measurement datum that represents a vaccine strain. Different strains can be represented using distinct digital numbers. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccine strain datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001189 obo:IAO_0000115 "A measurement datum that represents vaccine viability. 0 = live; 1 = irradiated; 2 = killed." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccine viability datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001190 obo:IAO_0000115 "A measurement datum that indicates the usage of a vaccine adjuvant. Different digital numbers can be used to represent different adjuvants. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccine adjuvant usage datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001191 obo:IAO_0000115 "A measurement datum that represents a specific protective antigen used in a vaccine. The antigen can be represented by a described digit. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccine protective antigen datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001192 obo:IAO_0000115 "A measurement datum that represents a specific mutated gene from a vaccine strain. The mutated can be represented by a described digit. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "mutated gene in vaccine strain datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001193 obo:IAO_0000115 """A measurement datum that represents a specific mouse strain used for vaccination. Different strains can be represented using discretized digitals. For example, 0 = BALB/c; 1 = CD1; 2 = mixed/outbred; 3 = C57BL/6; 4 = OF1; 5 = 129/Sv; 6 = Swiss albino. """ ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccination mouse strain datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001194 obo:IAO_0000115 "A measurement datum that represents the biological sex of an animal. The result can be represented using a discretized digit, for example, 0 = female; 1 = male." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "biological sex datum" ; rdfs:subClassOf obo:IAO_0000109, [ a owl:Restriction ; owl:onProperty obo:IAO_0000136 ; owl:someValuesFrom obo:PATO_0000047 ] . obo:VO_0001195 obo:IAO_0000115 """A measurement datum that represents a specific route (e.g., i.p.) used for vaccination. Different routes can be represented using discretized digitals. 0 = IP; 1 = PO; 2 = SC; 3 = IM; 4 = IN; 6 = IG; 7 = IV; 8 = ID. """ ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccination route datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001196 obo:IAO_0000115 "A vaccination dose that is used with the unit of colony forming units (CFU)." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccination dose (unit: CFU)" ; rdfs:subClassOf obo:VO_0000814 . obo:VO_0001197 obo:IAO_0000115 "An age range at vaccination that represents the animal age (unit: day) at the time of vaccination." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "animal age at vaccination in days" ; rdfs:subClassOf obo:VO_0004926 . obo:VO_0001198 obo:IAO_0000115 "A measurement datum that represents a specific pathogen strain used for animal challenge study. Different pathogen strains can be represented using discretized digitals. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "pathogen strain for challenge datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001199 obo:IAO_0000115 "A measurement datum that represents a specific pathogen used for animal challenge study. Different pathogens can be represented using discretized digitals. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "pathogen challenge datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001200 obo:IAO_0000116 "Native fucose-mannose-ligand antigen complex" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leishmune" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9615 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000205 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001201 obo:IAO_0000116 "Live oral vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Enterisol Ileitis" ; rdfs:subClassOf obo:VO_0001105, [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001202 obo:IAO_0000115 "A challenge dose that is represented with the unit of colony forming units (CFU)." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "challenge dose (unit: CFU)" ; rdfs:subClassOf obo:VO_0000900 . obo:VO_0001203 obo:IAO_0000115 "A measurement datum that represents a length of days as the interval between a vaccination and a challenge in a specific vaccine protection study. " ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccination-challenge interval in days" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001204 obo:IAO_0000115 "A colony forming unit (CFU) from the sample of mouse spleen." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "CFU per spleen" ; rdfs:subClassOf obo:VO_0000189 . obo:VO_0001205 obo:IAO_0000115 "A reduction of colony forming unit that was measured with the unit of colony forming units (CFU) from the sample of mouse spleen." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "CFU reduction per spleen" ; rdfs:subClassOf obo:VO_0001164 . obo:VO_0001206 obo:IAO_0000115 "A measurement datum that represents a type of vaccine protection efficacy as an outcome of a vaccine protection study. The result can be represented as a digit, for example, 0 = no protection, and 1 = protection (determined by a p-value cutoff)." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "He Y, Xiang Z, Todd T, Courtot M, Brinkman R, Zheng J, Stoeckert CJ, Malone J, Rocca-Serra P, Sansone S, Fostel J, Soldatova LN, Peters B, Rutternberg A. Ontology representation and ANOVA analysis of vaccine protection investigation. Proceeding of Bio-Ontologies 2010: Semantic Applications in Life Sciences, ISMB, July 9-10, 2010. Boston, MA, USA. Full length paper. URL: http://www.hegroup.org/docs/ANOVA_Vaccine_usecase_camera.pdf", "Todd TE, Tibi O, Lin Y, Sayers S, Bronner DN, Xiang Z, He Y. Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates. BMC Bioinformatics. 2013, 14(Suppl 6):S3. PMID: 23735014. PMCID: PMC3633026. " ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "vaccine protection efficacy datum" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0001207 obo:IAO_0000115 "A Chlamydia bacterial vaccine against Chlamydia trachomatis infection" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamydia trachomatis vaccine" ; rdfs:subClassOf obo:VO_0000573, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_813 ] . obo:VO_0001208 obo:IAO_0000115 "B. abortus BLS-L7/L12 is a B. abortus subunit vaccine using L7/L12 that is made as a recombinant BLS-L7/L12 fusion protein vaccine." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "recombinant Brucella BLS-L7/L12 fusion protein vaccine", "recombinant Brucella lumazine synthase and L7/L12 fusion protein vaccine" ; obo:IAO_0000119 "PMID: 19596411" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. abortus BLS-L7/L12" ; rdfs:subClassOf obo:VO_0000323 . obo:VO_0001209 obo:IAO_0000115 "vaccine protection efficacy measurement is an assay that measures the protection efficayc of a vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "assay" ; a owl:Class ; rdfs:label "vaccine protection efficacy measurement" ; rdfs:subClassOf obo:OBI_0000070 . obo:VO_0001210 obo:IAO_0000115 "a subunit vaccien that uses LPS as protective antigen" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "lipopolysaccharide subunit vaccine" ; rdfs:subClassOf obo:VO_0000534 . obo:VO_0001211 obo:IAO_0000115 "viral vaccine that is used to protect against African swine fever virus infection" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "African swine fever virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10497 ] . obo:VO_0001212 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Coopers Animal Health" . obo:VO_0001213 obo:IAO_0000115 "A viral vaccine that protects against infection with Foot-and-mouth disease virus." ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Foot-and-mouth disease virus vaccine" ; rdfs:subClassOf obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12110 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12110 ] . obo:VO_0001214 obo:IAO_0000115 "a bacterial vaccine that uses inactivated bacterial organism. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "inactivated bacterial vaccine" ; rdfs:subClassOf obo:VO_0000165, obo:VO_0000315, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000165 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] ) ] . obo:VO_0001215 obo:IAO_0000115 "an anti-reproductive vaccine for cattle. The vaccine is based on the established principle that antibodies to the hypothalamic releasing hormone, gonadotrophin releasing hormone (GnRH) block the action of GnRH on pituitary secretion of luteinizing hormone and follicle stimulating hormone, leading to gonadal atrophy in mammals. The vaccine comprises an immunogenic GnRH:ovalbumin conjugate formulated in a novel double adjuvant system and is administered in a two-dose treatment regimen. " ; obo:IAO_0000116 "LHRH peptide conjugated to ovalbumin; oil emulsion adjuvant", "withdrawn in 1996" ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://www.ncbi.nlm.nih.gov/pubmed/1370000" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaxstrate" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000759, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000972 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000877 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001216 obo:IAO_0000115 "A viral vaccine that protects against infection with Lymphocytic choriomeningitis mammarenavirus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lymphocytic choriomeningitis mammarenavirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052303 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052303 ] . obo:VO_0001217 obo:IAO_0000115 "a bacterial vaccine that is live and attenuated" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live attenuated bacterial vaccine" ; rdfs:subClassOf obo:VO_0000165, obo:VO_0000367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000165 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ] ) ] . obo:VO_0001218 obo:IAO_0000115 "Veterinary vaccine is a vaccine that is used for animals (excluding humans), for example, pet, domestic, wildlife, and livestock animals." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "veterinary vaccine" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0001219 obo:IAO_0000117 "YH" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Dow AgroSciences" . obo:VO_0001220 obo:IAO_0000115 "a viral vaccine that is live attenuated" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment """This term has an equivalent class: 'viral vaccine' and ('has quality at some time' some 'vaccine organism live attenuated') However, running the reasoner takes time. As a way to reducing the time, I have tentatively made tern two subclasses instead of equivalent class. If needed, the equivalent class can be used in SPARQL or converted back in VO. --Oliver """ ; rdfs:label "live attenuated viral vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ] ) ] . obo:VO_0001221 obo:IAO_0000115 "a B. abortus vaccine that uses subunit antigen" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus subunit vaccine" ; rdfs:subClassOf obo:VO_0000108, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ] . obo:VO_0001222 obo:IAO_0000115 "A viral vaccine that protects aganist Newcastle disease virus infection." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle disease virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560319 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560319 ] ) ] . obo:VO_0001223 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella melitensis subunit vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ] . obo:VO_0001224 obo:IAO_0000115 "A viral vaccine that protects against infection with Viral hemorrhagic septicemia virus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Viral hemorrhagic septicemia virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11287 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11287 ] . obo:VO_0001225 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus DNA vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000108, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ] . obo:VO_0001226 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella melitensis DNA vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ] . obo:VO_0001227 obo:IAO_0000115 "A viral vaccine that protects against infection with Human herpesvirus 5." ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human betaherpesvirus 5 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10359 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10359 ] . obo:VO_0001228 obo:IAO_0000115 "A viral vaccine that protects against infection with Coxsackievirus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coxsackievirus vaccine" ; rdfs:subClassOf obo:VO_0003547, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12066 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12066 ] . obo:VO_0001229 obo:IAO_0000115 "A protozoan vaccine that protects against infection with Schistosoma japonicum" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Schistosoma japonicum vaccine" ; rdfs:subClassOf obo:VO_0003047, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0001230 obo:IAO_0000115 "a bacterial vaccine against Treponema pallidum infection" ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Treponema pallidum vaccine" ; rdfs:subClassOf obo:VO_0003494, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_160 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_160 ] . obo:VO_0001231 obo:IAO_0000115 "A vaccine that protects against Leishmania major." ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leishmania major vaccine" ; rdfs:subClassOf obo:VO_0000762, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0001232 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "protective antigen" ; rdfs:subClassOf obo:OBI_1110034, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0001233 obo:IAO_0000115 "A vaccine preparation that results in the generation of a viral vaccine" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "viral vaccine preparation" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000609 ] . obo:VO_0001234 obo:IAO_0000115 "A vaccine preparation that results in the generation of a protozoan vaccine" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "protozoan vaccine preparation" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000417 ] . obo:VO_0001235 obo:IAO_0000115 "A vaccine preparation that results in the generation of a fungal vaccine" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "fungal vaccine preparation" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000267 ] . obo:VO_0001237 obo:IAO_0000115 "A microbial derivative vaccine adjuvant compsed of CpG DNA." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "PMID:12899580" ; a owl:Class ; rdfs:label "CpG DNA vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001238 obo:IAO_0000115 "An emulsion vaccine adjuvant that is a stable oil-in-water emulsion." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&N4=M6661%7CSIGMA&N25=0&QS=ON&F=SPEC" ; a owl:Class ; rdfs:label "Ribi vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001239 obo:IAO_0000115 "A synthetic vaccine adjuvant named RC529 that is a lipid A mimetic." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:16204643" ; a owl:Class ; rdfs:label "RC529 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001240 obo:IAO_0000115 "An aluminum vaccine adjuvant that is aluminum potassium sulfate (AlK(SO4)2)." ; obo:IAO_0000117 "Allen Xiang", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "aluminum potassium sulfate adjuvant" ; rdfs:subClassOf obo:VO_0000884 . obo:VO_0001241 obo:IAO_0000115 "An aluminum hydroxide vaccine adjuvant that is a gel that is made by precipitation of aluminum hydroxide Al(OH)3 under alkaline conditions." ; obo:IAO_0000117 "Allen Xiang", "Samantha G. Sayers" ; obo:IAO_0000118 "Alhydrogel" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Alhydrogel vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000127 . obo:VO_0001242 obo:IAO_0000115 "A cholera toxin derived vaccine adjuvant made of the B subunit of the cholera toxin from Vibrio cholerae." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "CTB", "cholera toxin B" ; a owl:Class ; rdfs:label "cholera toxin B subunit vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001348 . obo:VO_0001243 obo:IAO_0000115 """A shortcut relation that equals to: 'processed material' and (is_specified_output_of some 'vaccine preparation') and ('has function' some ('vaccine function' and ('is realized by' only ('vaccine immunization' and (realizes some ('vaccine host role' and (role_of some 'organism')))))))). The domain of this relation is a vaccine. The range of this relation is a organism.""" ; obo:IAO_0000117 "Asiyah Yu Lin", "Oliver He" ; obo:IAO_0000118 "immunization for host", "vaccine immunization for host" ; a owl:ObjectProperty ; rdfs:domain obo:VO_0000001 ; rdfs:label "immunizes organism" ; rdfs:range obo:OBI_0100026 . obo:VO_0001244 obo:IAO_0000117 "Allen Xiang, Oliver He, Kallan Roan" ; obo:IAO_0000119 "https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm201667.htm", "https://www.prevnar13.com/" ; obo:VO_0003099 "Prevnar 13" ; obo:VO_0003158 "Pneumococcal 13-valent Conjugate Vaccine (Diphtheria CRM197 Protein)" ; obo:VO_0003160 """- Active immunization for the prevention of invasive disease caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F in children 6 weeks through 5 years of age (prior to the 6th birthday). - Active immunization for the prevention of otitis media caused by S. pneumoniae serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F. No otitis media efficacy data are available for serotypes 1, 3, 5, 6A, 7F, and 19A In children 6 weeks through 5 years of age (prior to the 6th birthday). - Active immunization for the prevention of invasive disease caused by S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F in children 6 years through 17 years of age (prior to the 18th birthday). - Active immunization for the prevention of pneumonia and invasive disease caused by S. pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F in adults 18 years of age and older. - Limitations: Prevnar 13 does not protect against disease caused by S. pneumoniae serotypes that are not in the vaccine.""" ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM574852.pdf" ; obo:VO_0003162 "125324" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Prevnar 13" ; rdfs:seeAlso "CVX: 133", "VIOLIN Vaccine ID: 1114" ; rdfs:subClassOf obo:VO_0000424, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003049 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003333 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003334 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003335 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003337 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003338 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003339 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003340 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003341 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003342 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003343 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003344 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003345 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003346 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001245 obo:IAO_0000115 "SYNFLORIX is indicated for active immunization of infants and children from 6 weeks up to 5 years of age against Streptococcus pneumoniae serotypes 1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F and 23F and invasive disease caused by these serotypes (including sepsis, meningitis, bacteraemic pneumonia, pleural empyema and bacteraemia). " ; obo:IAO_0000117 "ZX" ; obo:IAO_0000119 "WEB: http://www.gsk.ca/english/docs-pdf/product-monographs/Synflorix.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Synflorix" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1115" ; rdfs:subClassOf obo:VO_0000675, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0001246 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm201342.htm" ; obo:VO_0003099 "Menveo" ; obo:VO_0003158 "Meningococcal (Groups A, C, Y, and W-135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine" ; obo:VO_0003160 "For active immunization to prevent invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y and W-135 when administered to individuals 2 months to 55 years of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM201349.pdf" ; obo:VO_0003162 "125300" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Menveo" ; rdfs:seeAlso "CVX: 136", "VIOLIN Vaccine ID: 1113" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0003441, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001256 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003049 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004836 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004837 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004838 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004839 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000971 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001247 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AREPANRIX H1N1" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1116" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0001248 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Intanza" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1117" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0001249 obo:IAO_0000115 "An aqueous formula of the synthetic vaccine adjuvant RC529." ; obo:IAO_0000116 "RC529-AF can be obtained from Corixa Corporation (Seattle, WA)." ; obo:IAO_0000118 "RC529 vaccine adjuvant in an aqueour formulation" ; obo:IAO_0000119 "PMID: 15308371" ; a owl:Class ; rdfs:label "RC529-AF vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001239 . obo:VO_0001250 obo:IAO_0000115 "A microbial derivative vaccine adjuvant derived from the lipopolysaccharide (LPS) of Salmonella minnesota R595." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "3-O-deacylated monophosphoryl lipid A vaccine adjuvant", "3D-MLA", "MPL vaccine adjuvant" ; obo:IAO_0000119 "PMID:7551218", "https://www.frontiersin.org/articles/10.3389/fimmu.2020.577823" ; a owl:Class ; rdfs:label "monophosphoryl lipid A vaccine adjuvant" ; rdfs:seeAlso "PMID:10768940" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001251 obo:IAO_0000115 "An E. coli LT toxin derived vaccine adjuvant that is a mutant form of LT containing a Ser-Lys substitution in position 63 which has been shown to be totally devoid of toxicity stable to protease treatment and able to act as mucosal adjuvant." ; obo:IAO_0000116 "LTK63 is an enzymatically inactive mutant of the heat-labile enterotoxin of Escherichia coli. It can be used as a potent mucosal adjuvant." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:9607006" ; a owl:Class ; rdfs:label "LTK63 vaccine mutant" ; rdfs:seeAlso "PMID:10790422", "PMID:17920733" ; rdfs:subClassOf obo:VO_0000388 . obo:VO_0001252 obo:IAO_0000115 "is a bacterial toxin (usually an exotoxin) whose toxicity has been weakened or suppressed either by chemical (formalin) or heat treatment, while other properties, typically immunogenicity, are maintained." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Toxoid" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "toxoid" ; rdfs:subClassOf obo:OBI_0000047 . obo:VO_0001253 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "capsular polysaccharide subunit vaccine" ; rdfs:subClassOf obo:VO_0001255 . obo:VO_0001254 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "capsular polysaccharide of pathogen organism as vaccine component" ; rdfs:subClassOf obo:VO_0001256 . obo:VO_0001255 obo:IAO_0000115 "a subunit vaccine that uses polysaccharide as protective antigen" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "polysaccharide subunit vaccine" ; rdfs:subClassOf obo:VO_0000534 . obo:VO_0001256 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "polysaccharide of pathogen organism as vaccine component" ; rdfs:subClassOf obo:VO_0000000 . obo:VO_0001257 obo:IAO_0000115 "The specification of an objective to prevent a disorder." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "prevention of disorder objective" ; rdfs:subClassOf obo:IAO_0000005 . obo:VO_0001258 obo:IAO_0000115 "The specification of an objective to ameliorate a disorder." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "amelioration of disorder objective" ; rdfs:subClassOf obo:IAO_0000005 . obo:VO_0001259 obo:IAO_0000115 "A microbial derivative vaccine adjuvant derived from heat-killed Corynebacterium parvum." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:5483667" ; a owl:Class ; rdfs:label "killed Corynebacterium parvum vaccine adjuvant" ; rdfs:seeAlso "PMID:4596278", "PMID:7591056" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001260 obo:IAO_0000115 "An emulsion vaccine adjuvant which is a water-in-oil adjuvant with CRL-8300 (a block copolymer), squalene, and sorbitan monooleate." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Titermax Gold" ; a owl:Class ; rdfs:label "Titermax Gold vaccine adjuvant" ; rdfs:seeAlso "URL: http://www.titermax.com/i_gold4.htm" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001261 obo:IAO_0000115 "A synthetic vaccine adjuvant that is dimethyldioctadecylammonium bromide (DDA), a lipophilic quaternary ammonium salt known as a good adjuvant when co-administered systemically or nasally with an antigen." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Dimethyl dioctadecyl ammonium bromide" ; a owl:Class ; rdfs:label "DDA vaccine adjuvant" ; rdfs:seeAlso "PMID:1439129" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001262 obo:IAO_0000115 "A liposome-based vaccine adjuvant that have a positive surface charge." ; obo:IAO_0000117 "Samantha G. Sayers" ; a owl:Class ; rdfs:label "cationic liposomal vaccine adjuvant DDA:TDB" ; rdfs:seeAlso "PMID:19874860" ; rdfs:subClassOf obo:VO_0000366 . obo:VO_0001263 obo:IAO_0000115 "A tenosactive compound vaccine adjuvant that contains purified extract from the bark of the South American tree Quillaja saponaria Molina." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "QuilA vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001358 . obo:VO_0001264 obo:IAO_0000115 "A combination vaccine adjuvant comprised of monophosphoryl lipid A (MPL), QS21 and an oil in water emulsion." ; obo:IAO_0000116 "monophosphoryl lipid A (MPL), QS21 and an oil in water emulsion." ; obo:IAO_0000117 "Samantha G. Sayers" ; a owl:Class ; rdfs:label "AS02 vaccine adjuvant" ; rdfs:seeAlso "PMID:15187142", "PMID:15780441" ; rdfs:subClassOf obo:VO_0001354 . obo:VO_0001265 obo:IAO_0000115 "A combination vaccine adjuvant that is a combination of 50 Œºg of the immunoenhancer MPL (3-O-desacyl-4‚Ä≤-monophosphoryl lipid A) with 500 Œºg of aluminium salt." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:21527299" ; a owl:Class ; rdfs:label "AS04 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354 . obo:VO_0001266 obo:IAO_0000115 "An emulsion vaccine adjuvant which is an emulsion plus DDA." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Emulsigen D", "VSA-3" ; obo:IAO_0000119 "PMID:16187717" ; a owl:Class ; rdfs:label "VSA-3 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001267 obo:IAO_0000115 "A tensoactive compound vaccine adjuvant that is derived from saponin, a compound that is an immunostimulator found in the plant P. senega." ; a owl:Class ; rdfs:label "saponin vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001358 . obo:VO_0001268 obo:IAO_0000115 "A Montanide vaccine adjuvant that is formulated as water-in-oil emulsions and induces high antibody titers in several animal species. It is a vaccine adjuvant composed of metabolizable oil and a surfactant system designed to make a water-in-oil emulsion. It has been used since 1992 in more than 50 clinical trials related to therapeutic vaccines against various diseases such as cancer and malaria." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "Montanide ISA 720", "Montanide ISA 720 VG" ; obo:IAO_0000119 "WEB: http://www.seppic.com/human-health/vaccine-adjuvant/montanide-isa-720-@/view-1044-seproduit.html?menuid=,979,&lang=en" ; a owl:Class ; rdfs:label "Montanide ISA 720 vaccine adjuvant" ; rdfs:seeAlso "PMID:15752840" ; rdfs:subClassOf obo:VO_0001271 . obo:VO_0001269 obo:IAO_0000115 "A Montanide vaccine adjuvant that is a mineral oil adjuvant." ; a owl:Class ; rdfs:label "Montanide incomplete Seppic adjuvant" ; rdfs:subClassOf obo:VO_0001271 . obo:VO_0001270 obo:IAO_0000115 "A Montanide vaccine adjuvant that is a vaccine adjuvant composed of a light mineral oil and a surfactant system designed to make a water-in-oil emulsion." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Montanide ISA51" ; obo:IAO_0000119 "WEB: http://www.seppic.com/human-health/vaccine-adjuvant/montanide-isa-51-@/view-1042-seproduit.html?menuid=,979,&lang=en" ; a owl:Class ; rdfs:label "Montanide ISA51 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001271 . obo:VO_0001271 obo:IAO_0000115 "An emulsion vaccine adjuvant developed by Montanide." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000119 "http://www.montanide.com/" ; a owl:Class ; rdfs:label "Montanide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001272 obo:IAO_0000115 "An E. coli LT toxin derived vaccine adjuvant composed of the B subunit of E. coli heat-labile toxin." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "B subunit of E. coli heat-labile enterotoxin" ; a owl:Class ; rdfs:label "EtxB vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000388 . obo:VO_0001273 obo:IAO_0000115 "A synthetic vaccine adjuvant with the tradename Polygen." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "Polygen vaccine adjuvant" ; rdfs:seeAlso "URL: http://www.mvp-technologies.com/adjuvants/Polygen%20Final%20Technical%20Bulletin.pdf" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001274 obo:IAO_0000115 "a role of host that contains vaccine. It is a role that inheres in an organism that is the target of a vaccine administration (vaccination process)." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine host role" ; rdfs:subClassOf obo:OBI_0000725, [ a owl:Restriction ; owl:onProperty obo:BFO_0000054 ; owl:someValuesFrom obo:VO_0000490 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:OBI_0100026 ] . obo:VO_0001275 obo:IAO_0000115 "A role that represents a target (i.e., some disorder) of immunization." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "immunization target role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0001276 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "bacterial vaccine immunization" ; rdfs:subClassOf obo:VO_0000494 . obo:VO_0001277 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "viral vaccine immunization" ; rdfs:subClassOf obo:VO_0000494 . obo:VO_0001278 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "cancer vaccine immunization" ; rdfs:subClassOf obo:VO_0000494 . obo:VO_0001279 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "parasite vaccine immunization" ; rdfs:subClassOf obo:VO_0000494 . obo:VO_0001280 oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "immunization target role of pathogen" ; rdfs:subClassOf obo:VO_0001275 . obo:VO_0001281 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "immunization target role of bacterial pathogen" ; rdfs:subClassOf obo:VO_0001280 . obo:VO_0001282 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "immunization target role of viral pathogen" ; rdfs:subClassOf obo:VO_0001280 . obo:VO_0001283 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "immunization target role of parasite pathogen" ; rdfs:subClassOf obo:VO_0001280 . obo:VO_0001284 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "immunization target role of fungal pathogen" ; rdfs:subClassOf obo:VO_0001280 . obo:VO_0001285 obo:IAO_0000115 "A carbohydrate vaccine adjuvant, which enhances both humoral and cell-mediated immunity to oligopeptides in experimental animal models." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Algal Glucan vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001359 . obo:VO_0001286 obo:IAO_0000115 "A combination vaccine adjuvant that suspension of 1-2≈í¬∫m ovoids of immune stimulant gamma inulin (g-IN) in which alum is embedded as a carrier for protein or other anionic antigens." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:1887671" ; a owl:Class ; rdfs:label "Algammulin vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354 . obo:VO_0001287 obo:IAO_0000115 "A synthetic vaccine adjuvant that is Bay R1005 (N-(2-Deoxy-2-L-leucylamino Œ≤-D-glucopyranosyl)-N-octadecyldodecanoylamide hydroacetate )." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "BAY R1005", "N-( 2-Deoxy-2-L-leucylamino-β-D-glucopyranosyl)-N-octadecyldodecanoylamide hydroacetate" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "BAY R1005 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001288 obo:IAO_0000115 "A synthetic vaccine adjuvant that is N, N-dioctadecyl-N‚Ä≤, N‚Ä≤-bis( 2-hydroxyethyl) propanediamine (Avridine)." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Avridine", "CP20,96", "N, N-dioctadecyl-N', N'-bis( 2-hydroxyethyl) propanediamine" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Avridine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001289 obo:IAO_0000115 "A calcium phosphate vaccine adjuvant that is a gel prepared by precipitating soluable calcium and phosphate salts." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "calcium phosphate gel" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "calcium phosphate gel vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000131 . obo:VO_0001290 obo:IAO_0000115 "A microbial derivative vaccine adjuvant composed of the CTA1-DD fusion protein." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "CTA1-DD gene fusion protein" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "cholera toxin A1-subunit-ProteinA D-fragment fusion protein" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001291 obo:IAO_0000115 "A mineral salt vaccine adjuvant that is composed of Deoxycholic acid sodium salt (DOC) complexed with aluminum hydroxide." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "DOC/Alum Complex" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "DOC/Alum Complex vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000093 . obo:VO_0001292 obo:IAO_0000115 "A carbohydrate adjuvant that is a highly specific activator of the alternative pathway of complement in vitro and in vivo, and is composed of linear (unbranched) b-D-(2-1) polyfructofuranosyl-a-D-glucose." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:3265692", "PMID:7551218" ; a owl:Class ; rdfs:label "gamma Inulin vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001359 . obo:VO_0001293 obo:IAO_0000115 "A combination vaccine adjuvant that is comprised of a mixture of GMDP, DDA, and Zinc L-proline salt complex (ZnPro8)." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:15953835", "PMID:7551218" ; a owl:Class ; rdfs:label "Gerbu vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354 . obo:VO_0001294 obo:IAO_0000115 "A cytokine vaccine adjuvant that includes GM-CSF." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "GM-CSF vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001295 obo:IAO_0000115 "A synthetic vaccine adjuvant containing GMDP, a higly effective primary adjuvant." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "GMDP", "N-acetylglucosaminyl-(b1-4)-N-acetylmuramyl-L-alanyl-D-isoglutamine" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "GMDP vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001296 obo:IAO_0000115 "An IFN-gamma vaccine adjuvant that is composed of recombinant hIFN-gamma." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "recombinant hIFN-gamma/Interferon-g vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001360 . obo:VO_0001297 obo:IAO_0000115 "A cytokine vaccine adjuvant that includes IL-1b." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "interleukin-1b vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001298 obo:IAO_0000115 "A cytokine vaccine adjuvant that includes IL-2." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "IL-2 vaccine adjuvant" ; a owl:Class ; rdfs:label "interleukin-2 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001299 obo:IAO_0000115 "A cytokine vaccine adjuvant that includes IL-7." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "IL-7 vaccine adjuvant" ; a owl:Class ; rdfs:label "interleukin-7 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001300 obo:IAO_0000115 "A synthetic vaccine adjuvant that includes loxoribine which is a guanosine analog derivatized at position N7 and C8, and activates TLR-7." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "7-allyl-8-oxoguanosine", "Loxoribine" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Loxoribine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001301 obo:IAO_0000115 "An emulsion vaccine adjuvant consisting of an oil (squalene)-in-water nano emulsion." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "MF59" ; obo:IAO_0000119 "PMID:20488726" ; a owl:Class ; rdfs:label "MF59 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001302 obo:IAO_0000115 "A liposome-based vaccine adjuvant that consists of liposomes containing the synthetic lipophilic analog of muramyl dipeptide, muramyl tripeptide phosphatidylethanolamine (MTP-PE)." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "MTP-PE", "MTP-PE Liposomes" ; obo:IAO_0000119 "PMID:1431559" ; a owl:Class ; rdfs:label "MTP-PE Liposomes vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000366 . obo:VO_0001303 obo:IAO_0000115 "A synthetic vaccine adjuvant made of murametide that has adjuvant activity similar to MDP." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Murametide", "Nac-Mur-L-Ala-D-Gln-OCH3" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Murametide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001304 obo:IAO_0000115 "A synthetic vaccine adjuvant called murapalmitine." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Murapalmitine", "Nac-Mur-L-Thr-D-isoGIn-sn-glyceroI dipalmitoyl" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Murapalmitine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001305 obo:IAO_0000115 "A synthetic vaccine adjuvant that includes an MDP analog called D-Murapalmitine." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "D-Murapalmitine", "Nac-Mur-D-Ala-D-isoGln-sn-glycerol dipalmitoyl" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "D-Murapalmitine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001306 obo:IAO_0000115 "A synthetic vaccine adjuvant that is composed of neuraminidase-galactose oxidase (NAGO) a mixture of mixture of the two enzymes-neuraminidase and galactose oxidase." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "NAGO", "Neuraminidase-galactose oxidase" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "NAGO vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001307 obo:IAO_0000115 "A synthetic vaccine adjuvant consisting of multi-lamellar vesicles comprising a mixture of non-ionic surfactant (e.g., 1-monopalmitoyl-rac-glycerol), cholesterol and dicetyl phosphate used as a primary vaccine adjuvant for entrapped antigen." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "NISV", "non-ionic surfactant vesicles" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "non-ionic surfactant vesicles vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001308 obo:IAO_0000115 "A synthetic vaccine adjuvant made from the emulsion polymerization of methyl methacrylate." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "PMMA", "Polymethyl methacrylate" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "PMMA vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001309 obo:IAO_0000115 "A synthetic vaccine adjuvant synthesized from stable protein phospholipid-calcium precipitates." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "protein cochleates" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "protein cochleates vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001310 obo:IAO_0000115 "A saponin vaccine adjuvant that is composed of extracts from the bark of the Quillaja saponaria Molina tree. Specifically, it is an acylated 3, 28-bisdesmodic triterpene glycosides (1,3) or ‚Äö√Ñ√∂‚àö√ë‚àö‚à´saponin‚Äö√Ñ√∂‚àö√ë‚àöœÄ with a molecular formula of C92O46H148 and molecular weight of 1990 Da. QS-21 is one of the active fractions of the bark of Chilean tree, Quillaja saponaria, purified using a reverse-phase chromatography (RP-HPLC)." ; obo:IAO_0000117 "Oliver He", "Randi Vita", "Samantha G. Sayers" ; obo:IAO_0000118 "QS-21", "Stimulon™ QS-21 Adjuvant" ; obo:IAO_0000119 "PMID:27213168", "PMID:7551218" ; a owl:Class ; rdfs:label "QS-21 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001267 . obo:VO_0001311 obo:IAO_0000115 "An aluminum vaccine adjuvant that is a synthetic oxyhydroxide of aluminum (aluminum hydroxide) prepared by acid-base precipitation." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Rehydragel HPA" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Rehydragel HPA vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000884 . obo:VO_0001312 obo:IAO_0000115 "An aluminum hydroxide vaccine adjuvant that is a low visosity aluminum hydroxide gel." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Rehydragel LV" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Rehydragel LV vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000127 . obo:VO_0001313 obo:IAO_0000115 "A cytokine vaccine adjuvant that contains the 163-171 peptide of IL-1β." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "IL-1β 163-171 peptide vaccine adjuvant", "Sclavo peptide" ; a owl:Class ; rdfs:label "Sclavo peptide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001314 obo:IAO_0000115 "An emulsion vaccine adjuvant that is a water-in-oil emulsion that is used as an adjuvant and has immunostimulating properties similar to Freund's complete adjuvant (FCA)." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Specol" ; obo:IAO_0000119 "PMID:1439130" ; a owl:Class ; rdfs:label "Specol vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001315 obo:IAO_0000115 "An emulsion vaccine adjuvant that is an emulsion of squalane (5%), Tween 80( 0.2%), Pluronic L121( 1.25%), phosphate-buffered saline pH 7.4, and antigen." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "SPT (Antigen Formulation)" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001316 obo:IAO_0000115 "A synthetic vaccine adjuvant stearyl tyrosine is considered an \"organic equivelant\" of aluminum hydroxide." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "stearyl tyrosine" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "stearyl tyrosine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001317 obo:IAO_0000115 "A synthetic vaccine adjuvant called Theramide that is composed of N-acetylglucosaminyl-N-acetylinuramyl-L-Ala-D-isoGlu-L-Ala-dipalmitoxy propylamide (DTP-DPP)." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Theramide" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Theramide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001318 obo:IAO_0000115 "A synthetic vaccine adjuvant that is a copolymer (CRL1005), based on a 12 kDa polyoxypropylene (POP) core with 5% POE." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "CRL1005" ; obo:IAO_0000119 "PMID:10717336" ; a owl:Class ; rdfs:label "CRL1005 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001319 obo:IAO_0000115 "An emulsion vaccine adjuvant and is made from non-toxic lipid droplets a few hundred nanometers in diameter and made from surfactants approved for human consumption and common food substances that are 'Generally Recognized as Safe' (GRAS) by the FDA." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "http://nano.med.umich.edu/platforms/Nanoemulsions.html" ; a owl:Class ; rdfs:label "nanoemulsion vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001320 obo:IAO_0000115 "An emusion vaccine adjuvant that contains ≈í¬±-tocopherol and squalene, two biodegradable polyprenyls, in an oil-in-water emulsion." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "AS03" ; obo:IAO_0000119 "PMID:21256188" ; a owl:Class ; rdfs:label "AS03 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001321 obo:IAO_0000115 "An E. coli LT toxin derived vaccine adjuvant that is a mutant form of E.coli heat-labile toxin." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "LTR192G" ; obo:IAO_0000119 "PMID:11803061" ; a owl:Class ; rdfs:label "LTR192G vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000388 . obo:VO_0001322 obo:IAO_0000115 "A microbial derivative vaccine adjuvant containing E. coli heat-labile toxin." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "E. coli heat-labile toxin, LT", "LT Oral Adjuvant", "LT-OA" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "E. coli heat-labile toxin vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001323 obo:IAO_0000115 "An aluminum vaccine adjuvant that is a a proprietary aluminum hydroxyphosphate sulfate formulation that is both physically and functionally distinct from traditional aluminum phosphate and aluminum hydroxide adjuvants." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "AAHSA", "Merck Aluminum Adjuvant" ; obo:IAO_0000119 "PMID:17581283" ; a owl:Class ; rdfs:label "amorphous aluminum hydroxyphosphate sulfate adjuvant" ; rdfs:subClassOf obo:VO_0000884 . obo:VO_0001324 obo:IAO_0000118 "Matrix-S" ; a owl:Class ; rdfs:label "Matrix-S vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001358 . obo:VO_0001325 obo:IAO_0000118 "Brucella BFR antigen vaccine", "recombinant Brucella abortus Bfr protein vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus subunit vaccine using Bfr" ; rdfs:seeAlso "PMID: 11447155" ; rdfs:subClassOf obo:VO_0001221 . obo:VO_0001326 obo:IAO_0000118 "Brucella abortus Omp16 vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus subunit vaccine using Omp16" ; rdfs:seeAlso "PMID: 18981242" ; rdfs:subClassOf obo:VO_0001221 . obo:VO_0001327 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis DNA vaccine encoding Bp26 and Tf" ; rdfs:subClassOf obo:VO_0001226 . obo:VO_0001328 obo:IAO_0000115 "A synthetic vaccine adjuvant contiaing imiquimod a imidazoquinoline." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "1-(2-methypropyl)-IH-imidazo[4,5-c]quinolin-4-amine", "Aldara™", "R-837", "S26308" ; obo:IAO_0000119 "PMID:18566444", "PMID:7551218" ; a owl:Class ; rdfs:label "imiquimod vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001329 obo:IAO_0000115 "A synthetic vaccine adjuvant, resiquimod is a chemical analog of imiquimod." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:15068862" ; a owl:Class ; rdfs:label "resiquimod vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001330 obo:IAO_0000115 "An emulsion vaccine adjuvant containing 2.5% squalene." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:20193791" ; a owl:Class ; rdfs:label "AF03 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0001331 obo:IAO_0000115 "A microbial derivative vaccine adjuvant composed of flagellin from gram-negative bacteria." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "FliC" ; obo:IAO_0000119 "PMID:16428759", "PMID:21048152" ; a owl:Class ; rdfs:label "Flagellin vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001332 obo:IAO_0000115 "A synthetic vaccine adjuvant containing Poly(I:C), a synthetic double stranded analog of RNA." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "polyriboinosinic-polyribocytidylic acid" ; obo:IAO_0000119 "WEB: http://en.wikipedia.org/wiki/Polyinosinic:polycytidylic_acid" ; a owl:Class ; rdfs:label "poly(I:C) vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001333 obo:IAO_0000115 "A particulate antigen delivery system that is a vaccine adjuvant comprising cholesterol, phospholipid and saponin but without antigen." ; obo:IAO_0000116 "ISCOMATRIX is identical to ISCOMs except that it does not contain antigen. Ref: PMID: 17336431." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:19450632" ; a owl:Class ; rdfs:label "ISCOMATRIX vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001356 . obo:VO_0001334 obo:IAO_0000115 "A saponin vaccine adjuvant that is made from highly purified saponins." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000119 "WEB: http://www.isconova.com/products/abisco-research-reagent/abisco-100.aspx" ; a owl:Class ; rdfs:label "Abisco-100 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001267 . obo:VO_0001335 obo:IAO_0000115 "A particulate antigen delivery system that is albumin-heparin microparticles vaccine adjuvant that is prepared from albumin and heparin stabilized by cross-linking reaction with EDC." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:16734558" ; a owl:Class ; rdfs:label "albumin-heparin microparticles vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001356 . obo:VO_0001336 obo:IAO_0000115 "A combination vaccine adjuvant and is based on the combination of Monophosphoryl Lipid A(MPL), QS21 (a purified fraction of Saponin extracted from Quillarja Saponaria), and a proprietary oil in water emulsion." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "http://www.pasteur.fr/applications/euroconf/vaccins/vaccins-abs.html" ; a owl:Class ; rdfs:label "AS-2 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354 . obo:VO_0001337 obo:IAO_0000115 "A cytokine vaccine adjuvant that includes B7-2." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "B7-2 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001338 obo:IAO_0000115 "A synthetic vaccine adjuvant that is a local anaesthetic drug belonging to the amino amide group, and is used as a vaccine adjuvant in DNA vaccines." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:15246629", "WEB: http://en.wikipedia.org/wiki/Bupivacaine" ; a owl:Class ; rdfs:label "Bupivacaine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001339 obo:IAO_0000115 "A liposome-based vaccine adjuvant that is composed of virus sized liposomes that contain a DNA plasmid." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "cationic liposome-DNA complex JVRS-100" ; obo:IAO_0000119 "PMID:19285425" ; a owl:Class ; rdfs:label "cationic liposome-DNA complex JVRS-100 vaccin adjuvant" ; rdfs:subClassOf obo:VO_0000366 . obo:VO_0001340 obo:IAO_0000115 "A synthetic vaccine adjuvant that is DHEA, which is relatively stable and can be directly incorporated into vaccine formulations." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "5-androsten-3β-ol-17-one", "DHA", "Dehydroepiandrosterone", "androstenolone", "prasterone", "transdehydroandrosterone" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "DHEA vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001341 obo:IAO_0000115 "A synthetic vaccine adjuvant that is PLGA, which has been used in the controlled delivery of peptide drugs." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "PLGA", "PLGA microspheres", "Polyester poly (DL-lactide-co-glycolide)" ; obo:IAO_0000119 "PMID:15560948" ; a owl:Class ; rdfs:label "DL-PGL (Polyester poly (DL-lactide-co-glycolide)) vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001342 obo:IAO_0000115 "A cytokine vaccine adjuvant that uses the adjuvant effect of cytokine IL-15." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "IL-15 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001343 obo:IAO_0000115 "A liposome-based vaccine adjuvant which is prepared from dehydration-rehydration vesicles (DRVs)." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "immunoliposomes containing antibodies to costimulatory molecules" ; rdfs:subClassOf obo:VO_0000366 . obo:VO_0001344 obo:IAO_0000115 "An E. coli LT toxin derived vaccine adjuvant that is a mutant form of heat-labile Escherichia coli enterotoxin (LT) that contains a substitution Ala ‚Äö√ú√≠ Arg in position 72 of the A subunit." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:9529328" ; a owl:Class ; rdfs:label "LTK72 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000388 . obo:VO_0001345 obo:IAO_0000115 "A microbial derivative vaccine adjuvant containing MPL and squalene." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:12213399" ; a owl:Class ; rdfs:label "MPL-SE vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001346 obo:IAO_0000115 "a vaccine preservative that contains formaldehyde." ; obo:IAO_0000117 "YH, SGS" ; obo:IAO_0000119 "WEB: http://www.mja.com.au/public/issues/184_04_200206/eld10500_fm.pdf" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "formaldehyde vaccine preservative" ; rdfs:subClassOf obo:VO_0000851, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000885 ] . obo:VO_0001347 obo:IAO_0000115 "A microbial derived vaccine adjuvant made of E112K mC, a mutated CT created by substituting a single amino acid in the ADP-ribosyltransferase active centre, glutamate to lysine at position 112." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "mCT", "non-toxic mutant E112K of Cholera Toxin mCT-E112K" ; obo:IAO_0000119 "PMID:11251876" ; a owl:Class ; rdfs:label "non-toxic mutant E112K of Cholera Toxin mCT-E112K vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001348 . obo:VO_0001348 obo:IAO_0000115 "A microbial derivative vaccine adjuvant that is derived from cholera toxin." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "cholera toxin derived vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001349 obo:IAO_0000115 "A combination vaccine adjuvant that is composed of threonyl-MDP (0.05-1%) in an emulsion vehicle [5% squalane, 2.5% Pluronic¬¨√Ü L121, 0.2% Polysorbate 80 and phosphate buffered saline (pH 7.4)]." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "SAF-1 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354 . obo:VO_0001350 obo:IAO_0000115 "A liposome-based vaccine adjuvant that includes the glycoproteins of Sendai virus." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "Sendai Proteoliposomes, Sendai-containing Lipid Matrices" ; rdfs:subClassOf obo:VO_0000366 . obo:VO_0001351 obo:IAO_0000115 "A synthetic vaccine adjuvant that is threonyl muramyl dipeptide (TMDP)." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "N-acetyl muramyl-L-threonyl-D-isoglutamine", "Termurtide™", "[thr1 ]-MDP" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "threonyl muramyl dipeptide (TMDP) vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001357 . obo:VO_0001352 obo:IAO_0000115 "A microbial derivative vaccine adjuvant made of virus like particles (VLPS) containing the yeast retrotransposon Ty which has the amino acids 1-381 of the pI protein encoded." ; obo:IAO_0000117 "Samantha G. Sayers" ; obo:IAO_0000118 "Ty-VLPs" ; obo:IAO_0000119 "PMID:7551218" ; a owl:Class ; rdfs:label "ty particles vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0001353 obo:IAO_0000115 "A vaccine adjuvant that contains active cytokine compound." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "cytokine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0001354 obo:IAO_0000115 "A vaccine adjuvant that is composed of differnt compounds under more than one category." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "combination vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0001355 a owl:Class ; rdfs:label "emulsion vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0001356 obo:IAO_0000115 "A vaccine adjuvant that serves as a particulate antigen delivery system." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "particulate antigen delivery system" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0001357 obo:IAO_0000115 "A vaccine adjuvant that contains synthetic material." ; obo:IAO_0000117 "Oliver He", "Philip Huang", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "synthetic vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0001358 obo:IAO_0000115 "A vaccine adjuvant that includes tensioactive material. Tensioactive materials, surfactants or active surface agents are chemical substances with a polar-non polar structure. These substances have a tendency to locate themselves at the surface creating an adsorbed monomolecular layer on the interface." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; obo:IAO_0000118 "tensioactive compound vaccine adjuvant" ; obo:IAO_0000119 "WEB: http://www.citt.ufl.edu/team/sepulveda/html/en_tensioactivos.htm" ; a owl:Class ; rdfs:label "tensoactive compound vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0001359 obo:IAO_0000115 "A vaccine adjuvant that is primarily composed of carbohydrates." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "carbohydrate vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0001360 obo:IAO_0000115 "A cytokine vaccine adjuvant that includes IFN-gamma." ; obo:IAO_0000117 "Oliver He", "Samantha G. Sayers" ; a owl:Class ; rdfs:label "IFN-gamma vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001353 . obo:VO_0001361 obo:IAO_0000115 "a role that is inherenced in a gene that can be mutated in a virulent pathogen, leading to an attenuated strain serving as a live attenuated vaccine strain." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "virmugen role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0001362 obo:IAO_0000115 "a vaccine that targets for allergy." ; obo:IAO_0000117 "YL,YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "allergy vaccine" ; rdfs:subClassOf obo:VO_0002813 . obo:VO_0001363 obo:IAO_0000115 "bacterial vaccine that is used to protect against Clostridium perfringens infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Clostridium perfringens vaccine" ; rdfs:subClassOf obo:VO_0000639, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1502 ] . obo:VO_0001364 oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "human immunization objective" ; rdfs:subClassOf obo:VO_0000585 . obo:VO_0001365 obo:IAO_0000115 "A viral vaccine that protects against infection with CCHF virus" ; obo:IAO_0000117 "YH, RS, NF" ; obo:IAO_0000118 "CCHF vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Crimean-Congo Haemorrhagic Fever vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052518 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052518 ] . obo:VO_0001366 obo:IAO_0000115 "A viral vaccine that protects against infection with Caprine herpesvirus type 1 virus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Caprine herpesvirus type 1 vaccine" ; rdfs:subClassOf obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_39944 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_39944 ] . obo:VO_0001367 obo:IAO_0000115 "an inactivation vaccine that is prepared by heat inactivation." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "heat-killed vaccine" ; rdfs:subClassOf obo:VO_0000017 . obo:VO_0001368 obo:IAO_0000115 "an inactivation vaccine that is prepared by irradiation inactivation." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "irradiation-inactivated vaccine" ; rdfs:subClassOf obo:VO_0000315 . obo:VO_0001369 obo:IAO_0000115 "an inactivation vaccine that is prepared by H2O2 inactivation." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H2O2-killed vaccine" ; rdfs:subClassOf obo:VO_0000017 . obo:VO_0001370 obo:IAO_0000115 "an inactivation vaccine that is prepared by formalin inactivation." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "formalin-killed vaccine" ; rdfs:subClassOf obo:VO_0000017 . obo:VO_0001371 obo:IAO_0000115 "A vaccine prepraration process that is performed by H2O2 inactivation of virulent pathogen." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "preparation of vaccine using H2O2 inactivation" ; rdfs:subClassOf obo:VO_0000178 . obo:VO_0001372 obo:IAO_0000115 "an organismal quality that indicates an organism (e.g., human) is not yet immunized against a disease." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "unimmunized" ; rdfs:subClassOf obo:PATO_0001995 . obo:VO_0001373 obo:IAO_0000115 "an organismal quality that indicates an organism (e.g., human) is immunized against a disease through vaccination with a licensed vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "immunized by vaccination with a licensed vaccine" ; rdfs:subClassOf obo:VO_0000151 . obo:VO_0001374 obo:IAO_0000115 "an organism that is vaccinated with a vaccine" ; obo:IAO_0000117 "YH, YL, MC" ; obo:IAO_0000118 "vaccinated organism" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "vaccinee" ; rdfs:subClassOf obo:OBI_0100026 . obo:VO_0001375 obo:IAO_0000115 "A Streptococcus vaccine against Streptococcus agalactiae infection." ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus agalactiae vaccine" ; rdfs:subClassOf obo:VO_0000772, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1311 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1311 ] . obo:VO_0001376 obo:IAO_0000115 "an organismal quality that indicates an organism (e.g., human) is vaccinated with a vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccinated" ; rdfs:subClassOf obo:PATO_0001995 . obo:VO_0001377 obo:IAO_0000115 "an organismal quality that indicates an organism (e.g., human) is unvaccinated with any vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "unvaccinated" ; rdfs:subClassOf obo:PATO_0001995 . obo:VO_0001378 obo:IAO_0000115 "a vaccinated quality that indicates an organism is vaccinated with a licensed vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "vaccinated with a licensed vaccine" ; rdfs:subClassOf obo:VO_0001376 . obo:VO_0001379 obo:IAO_0000115 "a unvaccinated quality that indicates an organism has not been vaccinated with a licensed vaccine." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:label "unvaccinated with a licensed vaccine" ; rdfs:subClassOf obo:VO_0001377 . obo:VO_0001380 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:8306370", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3066" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/295" ; obo:VO_0001818 "3066" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "B16 Vaccine adjuvanted by Loxoribine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000344 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0001381 obo:IAO_0000115 "an organism that is immunized for a disease" ; obo:IAO_0000117 "YH, YL, MC" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "immunized organism" ; rdfs:subClassOf obo:OBI_0100026 . obo:VO_0001382 obo:IAO_0000115 "A viral vaccine that protects against infection with Rabbit hemorrhagic disease virus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rabbit hemorrhagic disease virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11976 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11976 ] . obo:VO_0001383 obo:IAO_0000115 "an organism that is unvaccinated with a vaccine" ; obo:IAO_0000117 "YH, YL, MC" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:label "unvaccinated organism" ; rdfs:subClassOf obo:OBI_0100026 . obo:VO_0001384 obo:IAO_0000115 "A bacterial gene from Actinobacillus pleuropneumoniae." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Actinobacillus pleuropneumoniae gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_715 ] . obo:VO_0001385 obo:IAO_0000115 "A vaccine that protects against Trypanosoma cruzi." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "T. cruzi vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trypanosoma cruzi vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5693 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5693 ] . obo:VO_0001386 obo:IAO_0000115 "A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi CRP-10 protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine encoding CRP-10" ; rdfs:seeAlso "VIOLIN Vaccine ID: 803" ; rdfs:subClassOf obo:VO_0001385 . obo:VO_0001387 obo:IAO_0000115 "A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi G2 protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine encoding G2" ; rdfs:seeAlso "VIOLIN Vaccine ID: 807" ; rdfs:subClassOf obo:VO_0001385 . obo:VO_0001388 obo:IAO_0000115 "A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi G4 protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine encoding G4" ; rdfs:seeAlso "VIOLIN Vaccine ID: 809" ; rdfs:subClassOf obo:VO_0001385 . obo:VO_0001389 obo:IAO_0000115 "A T. cruzi DNA vaccine that uses a DNA plasmid expressing T. cruzi TSA-1 protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine encoding TSA-1" ; rdfs:seeAlso "VIOLIN Vaccine ID: 812" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011296 ] . obo:VO_0001390 obo:IAO_0000115 "A T. cruzi DNA vaccine that uses a DNA plasmid pGFP expressing T. cruzi TSA-1 protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine pGFP-TSA1" ; rdfs:seeAlso "VIOLIN Vaccine ID: 811" ; rdfs:subClassOf obo:VO_0001385 . obo:VO_0001391 obo:IAO_0000115 "A T. cruzi subunit vaccine that uses T. cruzi PAR1 protein as protective antigen." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi PAR1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 806" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:VO_0011301 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] ) ] ] . obo:VO_0001392 obo:IAO_0000115 "A T. cruzi subunit vaccine that uses T. cruzi PAR2 protein as protective antigen." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi PAR2 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 810" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:VO_0000894 ; owl:someValuesFrom obo:VO_0011301 ] . obo:VO_0001393 obo:IAO_0000115 "A T. cruzi vaccine that uses attenuated Salmonella to express T. cruzi Cruzipain protein." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi vaccine using attenuated Salmonella expressing T. cruzi Cruzipain" ; rdfs:seeAlso "VIOLIN Vaccine ID: 804" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:VO_0000894 ; owl:someValuesFrom obo:VO_0011293 ] . obo:VO_0001394 obo:IAO_0000115 "A T. cruzi vaccine that uses Sendai virus vector to express T. cruzi amastigote surface protein-2." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi vaccine using Sendai virus vector expressing amastigote surface protein-2" ; rdfs:seeAlso "VIOLIN Vaccine ID: 802" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:VO_0000894 ; owl:someValuesFrom obo:VO_0011289 ] . obo:VO_0001395 obo:IAO_0000115 "a vaccine that contains two or more individual vaccines. " ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cocktail vaccine" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0001396 obo:IAO_0000115 "a cocktail vaccine that contains both subunit vaccine and inactivated whole organism vaccines." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cocktail vaccine containing subunit vaccine and inactivated whole organism vaccine" ; rdfs:subClassOf obo:VO_0001395 . obo:VO_0001397 obo:IAO_0000115 "a prime-boost vaccine with DNA vaccine priming that contains a subunit vaccine for boosting" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccine containing DNA vaccine for priming and subunit vaccine for boosting" ; rdfs:subClassOf obo:VO_0000401 . obo:VO_0001398 obo:IAO_0000115 "a prime-boost vaccine with a DNA vaccine priming that contains a Ad vector vaccine for boosting" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccine containing DNA vaccine for priming and Ad vector vaccine for boosting" ; rdfs:subClassOf obo:VO_0000401 . obo:VO_0001399 obo:IAO_0000115 "a conjugate vaccine that conjugate more than one open reading frames of protective antigens or conjugate a protective antigen to a carrier protein." ; obo:IAO_0000116 "An example of fusion protein vaccine is Mtb72f fusion protein vaccine. Reference: PubMed: 15187142." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "fusion protein vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "fusion conjugate protein vaccine" ; rdfs:subClassOf obo:VO_0000195 . obo:VO_0001400 obo:IAO_0000115 "A Brucella gene that is from B. melitensis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Brucella melitensis gene" ; rdfs:subClassOf obo:VO_0000790, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_29459 ] . obo:VO_0001401 obo:IAO_0000115 "A Brucella gene that is from B. suis." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Brucella suis gene" ; rdfs:subClassOf obo:VO_0000790, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_29461 ] . obo:VO_0001402 obo:IAO_0000115 "A bacterial gene that is from Bacillus anthracis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Bacillus anthracis gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0001403 obo:IAO_0000115 "A bacterial gene that is from Listeria monocytogenes." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Listeria monocytogenes gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_1639 ] . obo:VO_0001404 obo:IAO_0000115 "A bacterial gene that is from Mycobacterium avium." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Mycobacterium avium gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_1764 ] . obo:VO_0001405 obo:IAO_0000115 "A bacterial gene that is from Staphylococcus aureus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Staphylococcus aureus gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0001406 obo:IAO_0000115 "A bacterial gene that is from Aeromonas hydrophila." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Aeromonas hydrophila gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_644 ] . obo:VO_0001407 obo:IAO_0000115 "A bacterial gene that is from Bordetella bronchiseptica." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Bordetella bronchiseptica gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_518 ] . obo:VO_0001408 obo:IAO_0000115 "A bacterial gene that is from Aeromonas salmonicida." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Aeromonas salmonicida gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_645 ] . obo:VO_0001409 obo:IAO_0000115 "A bacterial gene that is from Bordetella pertussis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Bordetella pertussis gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_520 ] . obo:VO_0001410 obo:IAO_0000115 "A bacterial gene that is from Borrelia burgdorferi." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Borrelia burgdorferi gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0001411 obo:IAO_0000115 "A bacterial gene that is from Burkholderia pseudomallei." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Burkholderia pseudomallei gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_28450 ] . obo:VO_0001412 obo:IAO_0000115 "A bacterial gene that is from Edwardsiella ictaluri." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Edwardsiella ictaluri gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_28450 ] . obo:VO_0001413 obo:IAO_0000115 "A bacterial gene that is from Edwardsiella tarda." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Edwardsiella tarda gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_636 ] . obo:VO_0001414 obo:IAO_0000115 "A bacterial gene that is from Francisella tularensis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Francisella tularensis gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_263 ] . obo:VO_0001415 obo:IAO_0000115 "A bacterial gene that is from Mannheimia haemolytica." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Mannheimia haemolytica gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_75985 ] . obo:VO_0001416 obo:IAO_0000115 "A bacterial gene that is from Mycoplasma gallisepticum." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Mycoplasma gallisepticum gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_2096 ] . obo:VO_0001417 obo:IAO_0000115 "A bacterial gene that is from Neisseria meningitidis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Neisseria meningitidis gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0001418 obo:IAO_0000115 "A bacterial gene that is from Pasteurella multocida." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Pasteurella multocida gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_747 ] . obo:VO_0001419 obo:IAO_0000115 "A bacterial gene that is from Salmonella Typhi." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Salmonella Typhi gene" ; rdfs:subClassOf obo:VO_0000168, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_90370 ] . obo:VO_0001420 obo:IAO_0000115 "A bacterial gene that is from Salmonella Gallinarum." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Salmonella Gallinarum gene" ; rdfs:subClassOf obo:VO_0000168, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_594 ] . obo:VO_0001421 obo:IAO_0000115 "A bacterial gene that is from Salmonella Typhimurium." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Salmonella Typhimurium gene" ; rdfs:subClassOf obo:VO_0000168, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_90371 ] . obo:VO_0001422 obo:IAO_0000115 "A bacterial gene that is from Salmonella Enteritidis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Salmonella Enteritidis gene" ; rdfs:subClassOf obo:VO_0000168, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_149539 ] . obo:VO_0001423 obo:IAO_0000115 "A bacterial gene that is from Vibrio cholerae." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Vibrio cholerae gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_666 ] . obo:VO_0001424 obo:IAO_0000115 "A viral gene that is from Bovine herpesvirus 1." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0001425 obo:IAO_0000115 "A bacterial gene that is from Yersinia enterocolitica." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Yersinia enterocolitica gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_150052 ] . obo:VO_0001426 obo:IAO_0000115 "A bacterial gene that is from Yersinia pestis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Yersinia pestis gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0001427 obo:IAO_0000115 "A bacterial gene that is from Yersinia pseudotuberculosis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Yersinia pseudotuberculosis gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_633 ] . obo:VO_0001428 obo:IAO_0000115 "A bacterial gene that is from Yersinia ruckeri." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Yersinia ruckeri gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_29486 ] . obo:VO_0001429 obo:IAO_0000115 "A viral gene that is from Bovine Respiratory Syncytial Virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Bovine Respiratory Syncytial Virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11246 ] . obo:VO_0001430 obo:IAO_0000115 "A viral gene that is from Classical swine fever virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Classical swine fever virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11096 ] . obo:VO_0001431 obo:IAO_0000115 "A viral gene that is from Equid herpesvirus 1." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Equid herpesvirus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_10326 ] . obo:VO_0001432 obo:IAO_0000115 "A viral gene that is from Feline herpesvirus 1." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Feline herpesvirus 1 gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_10334 ] . obo:VO_0001433 obo:IAO_0000115 "A viral gene that is from Feline immunodeficiency virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Feline immunodeficiency virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11673 ] . obo:VO_0001434 obo:IAO_0000115 "A viral gene that is from Feline infectious peritonitis virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Feline infectious peritonitis virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11135 ] . obo:VO_0001435 obo:IAO_0000115 "A viral gene that is from Gallid herpesvirus 1." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Gallid herpesvirus 1 gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0001436 obo:IAO_0000115 "A viral gene that is from Hepatitis B virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Hepatitis B virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0001437 obo:IAO_0000115 "A viral gene that is from Human herpesvirus 1." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Human herpesvirus 1 gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0001438 obo:IAO_0000115 "A viral gene that is from Human metapneumovirus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Human metapneumovirus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_162145 ] . obo:VO_0001439 obo:IAO_0000115 "A viral gene that is from Human Respiratory Syncytial Virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Human Respiratory Syncytial Virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11250 ] . obo:VO_0001440 obo:IAO_0000115 "A viral gene that is from Infectious Hematopoietic Necrosis Virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Infectious Hematopoietic Necrosis Virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11290 ] . obo:VO_0001441 obo:IAO_0000115 "A viral gene that is from Porcine respiratory and reproductive syndrome virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Porcine respiratory and reproductive syndrome virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0001442 obo:IAO_0000115 "A viral gene that is from Pseudorabies virus." ; obo:IAO_0000117 "YH, RR" ; obo:IAO_0000118 "Suid herpesvirus 1 gene" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Pseudorabies virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0001443 obo:IAO_0000115 "A viral gene that is from Rabies virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Rabies virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0001444 obo:IAO_0000115 "A viral gene that is from SARS-CoV." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "SARS-CoV gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0001445 obo:IAO_0000115 "A viral gene that is from Simian Immunodeficiency Virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Simian Immunodeficiency Virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11723 ] . obo:VO_0001446 obo:IAO_0000115 "A viral gene that is from Tick-borne Encephalitis Virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Tick-borne Encephalitis Virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11084 ] . obo:VO_0001447 obo:IAO_0000115 "A viral gene that is from VEE Virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "VEE Virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0001448 obo:IAO_0000115 "A viral gene that is from West Nile virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:hasAlternativeId "VO:0000197" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "West Nile virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11082 ] . obo:VO_0001449 obo:IAO_0000115 "A viral gene that is from Western equine encephalomyelitis virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Western equine encephalomyelitis virus gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_11039 ] . obo:VO_0001450 obo:IAO_0000115 "A protozoan gene that is from Leishmania donovani." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Leishmania donovani gene" ; rdfs:subClassOf obo:VO_0000174, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0001451 obo:IAO_0000115 "A Plasmodium gene that is from Plasmodium berghei." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Plasmodium berghei gene" ; rdfs:subClassOf obo:VO_0000171, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5821 ] . obo:VO_0001452 obo:IAO_0000115 "A Plasmodium gene that is from Plasmodium yoelii." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Plasmodium yoelii gene" ; rdfs:subClassOf obo:VO_0000171, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5861 ] . obo:VO_0001453 obo:IAO_0000115 "A protozoan gene that is from Toxoplasma gondii." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Toxoplasma gondii gene" ; rdfs:subClassOf obo:VO_0000170, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0001454 obo:IAO_0000115 "A viral gene that is from Human herpesvirus 2." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Human herpesvirus 2 gene" ; rdfs:subClassOf obo:VO_0000156, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_10310 ] . obo:VO_0001455 obo:IAO_0000115 "A viral vaccine that protects against infection with Rinderpest virus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rinderpest virus vaccine" ; rdfs:subClassOf obo:VO_0003543, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11241 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11241 ] . obo:VO_0001456 obo:IAO_0000115 "bacterial vaccine that is used to protect against Erysipelothrix rhusiopathiae infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Erysipelothrix rhusiopathiae vaccine" ; rdfs:subClassOf obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1648 ] . obo:VO_0001457 obo:IAO_0000115 "protozoan vaccine that is used to protect against Tritrichomonas suis infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trichomonas foetus vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_56690 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_56690 ] . obo:VO_0001458 obo:IAO_0000117 "YL" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "International Duck Research Cooperative, Inc." ; rdfs:seeAlso "http://www.duckhealth.com/idrc.html" . obo:VO_0001459 obo:IAO_0000115 "protozoan vaccine that is used to protect against Eimeria spp. (Eimeria) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Eimeria spp. vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5800 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5800 ] . obo:VO_0001460 obo:IAO_0000115 "viral vaccine that is used to protect against Orf Virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Orf Virus vaccine" ; rdfs:subClassOf obo:VO_0000512, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10258 ] . obo:VO_0001461 obo:IAO_0000115 "Vaccine that used for immunizing Aves." ; obo:IAO_0000117 "YL." ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Aves vaccine" ; rdfs:subClassOf obo:VO_0001218, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8782 ] . obo:VO_0001462 obo:IAO_0000115 "vaccine that used for immunizing fishes" ; obo:IAO_0000117 "YL." ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "fish vaccine" ; rdfs:subClassOf obo:VO_0001218 . obo:VO_0001463 obo:IAO_0000115 "viral vaccine that is used to protect against Fowlpox virus infection" ; obo:IAO_0000117 "YL" ; obo:IAO_0000118 "Fowl pox vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowlpox virus vaccine" ; rdfs:subClassOf obo:VO_0000512, obo:VO_0000985, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ] . obo:VO_0001464 obo:IAO_0000115 "vaccine that used for immunizing carnivora." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "carnivora vaccine" ; rdfs:subClassOf obo:VO_0001218 . obo:VO_0001465 obo:IAO_0000115 "vaccine that used for immunizing cat (felis catus)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cat vaccine" ; rdfs:subClassOf obo:VO_0001464 . obo:VO_0001466 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cattle vaccine" ; rdfs:subClassOf obo:VO_0001218 . obo:VO_0001467 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "dog vaccine" ; rdfs:subClassOf obo:VO_0001464 . obo:VO_0001468 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "chicken vaccine" ; rdfs:subClassOf obo:VO_0000390 . obo:VO_0001469 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ducks vaccine" ; rdfs:subClassOf obo:VO_0001461 . obo:VO_0001470 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "catfish vaccine" ; rdfs:subClassOf obo:VO_0001462 . obo:VO_0001471 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "gray wolf vaccine" ; rdfs:subClassOf obo:VO_0001464 . obo:VO_0001472 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "horse vaccine" ; rdfs:subClassOf obo:VO_0001218 . obo:VO_0001473 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "parrot vaccine" ; rdfs:subClassOf obo:VO_0001461 . obo:VO_0001474 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pig vaccine" ; rdfs:subClassOf obo:VO_0001218 . obo:VO_0001475 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "sei whale vaccine" ; rdfs:subClassOf obo:VO_0001218 . obo:VO_0001476 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "sheep vaccine" ; rdfs:subClassOf obo:VO_0001218 . obo:VO_0001477 obo:IAO_0000115 "vaccine that used for immunizing salmoninae (tourts, salmons & chars )" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "salmoninae vaccine" ; rdfs:subClassOf obo:VO_0001218 . obo:VO_0001478 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "turkey vaccine" ; rdfs:subClassOf obo:VO_0001461 . obo:VO_0001479 obo:IAO_0000115 "The objective that intends to produce vaccine via the vaccine preparation process." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "information content entity" ; a owl:Class ; rdfs:label "vaccine target specification" ; rdfs:subClassOf obo:IAO_0000005 . obo:VO_0001480 obo:IAO_0000115 "A viral vaccine that protects against infection with African horse sickness virus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "African horse sickness virus vaccine" ; rdfs:subClassOf obo:VO_0003542, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40050 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40050 ] . obo:VO_0001481 obo:IAO_0000115 "viral vaccine that is used to protect against Pigeonpox virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pigeonpox virus vaccine" ; rdfs:subClassOf obo:VO_0000512, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10264 ] . obo:VO_0001482 obo:IAO_0000115 "viral vaccine that is used to protect against Bovine herpesvirus 1 infection" ; obo:IAO_0000117 "YL, YH" ; obo:IAO_0000118 "BHV-1 vaccine", "Bovine rhinotracheitis vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bovine herpesvirus 1 vaccine" ; rdfs:subClassOf obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] ) ] . obo:VO_0001483 obo:IAO_0000115 "A viral vaccine that protects against infection with Borna disease virus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Borna disease virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12455 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12455 ] . obo:VO_0001484 obo:IAO_0000115 "A viral vaccine that protects against infection with Caprine herpesvirus 1" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Caprine herpesvirus 1 vaccine" ; rdfs:subClassOf obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_39944 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_39944 ] . obo:VO_0001485 obo:IAO_0000115 "A vaccine licensed in the USA" ; obo:IAO_0000117 "Oliver He, Kallan Roan" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm093833.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "USA licensed vaccine" ; rdfs:subClassOf obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001486 obo:IAO_0000115 "viral vaccine that is used to protect against Equid herpesvirus 1 infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equid herpesvirus 1 vaccine" ; rdfs:subClassOf obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10326 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10326 ] ) ] . obo:VO_0001487 obo:IAO_0000115 "viral vaccine that is used to protect against Feline herpesvirus 1 (Felid herpesvirus 1) infection" ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline herpesvirus 1 vaccine" ; rdfs:subClassOf obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10334 ] . obo:VO_0001488 obo:IAO_0000115 "viral vaccine that is used to protect against Gallid herpesvirus 1 infection" ; obo:IAO_0000117 "YL, YH, RS, NF" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Gallid_herpesvirus_1" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Gallid herpesvirus 1 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0001489 obo:IAO_0000115 "viral vaccine that is used to protect against Canine adenovirus type 1 (Canine adenovirus 1) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "canine adenovirus type 1 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10512 ] . obo:VO_0001490 obo:IAO_0000115 "viral vaccine that is used to protect against Canine Adenovirus Type 2 (Canine adenovirus 2) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "canine adenovirus Type 2 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10514 ] . obo:VO_0001491 obo:IAO_0000115 "viral vaccine that is used to protect against Bovine papillomavirus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine papillomavirus vaccine" ; rdfs:subClassOf obo:VO_0000748, obo:VO_0003538, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10571 ] . obo:VO_0001492 obo:IAO_0000115 "viral vaccine that is used to protect against Avian Polyomavirus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian polyomavirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1891747 ] . obo:VO_0001493 obo:IAO_0000115 "viral vaccine that is used to protect against Mink enteritis virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink enteritis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10792 ] . obo:VO_0001494 obo:IAO_0000115 "viral vaccine that is used to protect against Porcine parvovirus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine parvovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10796 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10796 ] ) ] . obo:VO_0001495 obo:IAO_0000115 "viral vaccine that is used to protect against Porcine rotavirus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine rotavirus vaccine" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10913 ] . obo:VO_0001496 obo:IAO_0000115 "viral vaccine that is used to protect against Equine rotavirus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine rotavirus vaccine" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10937 ] . obo:VO_0001497 obo:IAO_0000115 "viral vaccine that is used to protect against Infectious Bursal Disease Virus (IBDV) infection" ; obo:IAO_0000117 "YL, YH, RS, NF" ; obo:IAO_0000118 "IBDV vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "infectious bursal disease virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] ) ] . obo:VO_0001498 obo:IAO_0000115 "viral vaccine that is used to protect against Eastern Equine Encephalitis Virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Eastern Equine Encephalitis Virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11021 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11021 ] ) ] . obo:VO_0001499 obo:IAO_0000115 "viral vaccine that is used to protect against VEE Virus (Venezuelan equine encephalitis virus) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VEE Virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] ) ] . obo:VO_0001500 obo:IAO_0000115 "viral vaccine that is used to protect against Equine arteritis virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine arteritis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11047 ] . obo:VO_0001501 obo:IAO_0000115 "viral vaccine that is used to protect against Bovine viral diarrhea virus 1 infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine viral diarrhea virus 1 vaccine" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ] . obo:VO_0001502 obo:IAO_0000115 "viral vaccine that is used to protect against Infectious Bronchitis Virus (IBV) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infectious Bronchitis Virus vaccine" ; rdfs:subClassOf obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] ) ] . obo:VO_0001503 obo:IAO_0000115 "viral vaccine that is used to protect against Bovine coronavirus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bovine coronavirus vaccine" ; rdfs:subClassOf obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11128 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11128 ] . obo:VO_0001504 obo:IAO_0000115 "viral vaccine that is used to protect against Feline infectious peritonitis virus infection" ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline infectious peritonitis virus vaccine" ; rdfs:subClassOf obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11135 ] . obo:VO_0001505 obo:IAO_0000115 "viral vaccine that is used to protect against Transmissible gastroenteritis virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Transmissible gastroenteritis virus vaccine" ; rdfs:subClassOf obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11149 ] . obo:VO_0001506 obo:IAO_0000115 "viral vaccine that is used to protect against Bovine Parainfluenza 3 Virus (BPIV-3) (Bovine parainfluenza virus 3) infection" ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Parainfluenza 3 Virus vaccine" ; rdfs:subClassOf obo:VO_0000451, obo:VO_0000990, obo:VO_0002485, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000451 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] ) ] . obo:VO_0001507 obo:IAO_0000115 "viral vaccine that is used to protect against Bovine Respiratory Syncytial Virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Respiratory Syncytial Virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11246 ] . obo:VO_0001508 obo:IAO_0000115 "viral vaccine that is used to protect against Feline immunodeficiency virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline immunodeficiency virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11673 ] . obo:VO_0001509 obo:IAO_0000115 "viral vaccine that is used to protect against Feline calicivirus infection" ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline calicivirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11978 ] . obo:VO_0001510 obo:IAO_0000115 "viral vaccine that is used to protect against Chicken Anemia Virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "chicken anemia virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12618 ] . obo:VO_0001511 obo:IAO_0000115 "viral vaccine that is used to protect against Porcine respiratory and reproductive syndrome virus (Porcine reproductive and respiratory syndrome virus) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine respiratory and reproductive syndrome virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0001512 obo:IAO_0000115 "bacterial vaccine that is used to protect against Riemerella anatipestifer infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Riemerella anatipestifer vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_34085 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_34085 ] . obo:VO_0001513 obo:IAO_0000115 "viral vaccine that is used to protect against Avian Reovirus (Avian orthoreovirus) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian reovirus vaccine" ; rdfs:subClassOf obo:VO_0003541, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ] . obo:VO_0001514 obo:IAO_0000115 "viral vaccine that is used to protect against Avian pneumovirus (Avian metapneumovirus) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian pneumovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38525 ] . obo:VO_0001515 obo:IAO_0000115 "viral vaccine that is used to protect against Bluetongue virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bluetongue virus vaccine" ; rdfs:subClassOf obo:VO_0003542, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40051 ] . obo:VO_0001516 obo:IAO_0000115 "viral vaccine that is used to protect against Turkey hemorrhagic enteritis virus (Turkey adenoirus 3) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Turkey hemorrhagic enteritis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_41678 ] . obo:VO_0001517 obo:IAO_0000115 "viral vaccine that is used to protect against Canarypox virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canarypox virus vaccine" ; rdfs:subClassOf obo:VO_0000512, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_44088 ] . obo:VO_0001518 obo:IAO_0000115 "viral vaccine that is used to protect against Psittacid herpesvirus 1 infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Psittacid herpesvirus 1 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_50294 ] . obo:VO_0001519 obo:IAO_0000115 "A vaccine that protects against infection with Mycobacterium bovis" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycobacterium bovis vaccine" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1765 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1765 ] . obo:VO_0001520 obo:IAO_0000115 "viral vaccine that is used to protect against Infectious salmon anemia virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infectious salmon anemia virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_55987 ] . obo:VO_0001521 obo:IAO_0000115 "An Edwardsiella bacterial vaccine that is used to protect against Edwardsiella ictaluri infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Edwardsiella ictaluri vaccine" ; rdfs:subClassOf obo:VO_0000602, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_67780 ] . obo:VO_0001522 obo:IAO_0000115 "viral vaccine that is used to protect against Avian Encephalomyelitis Virus infection" ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian encephalomyelitis virus vaccine" ; rdfs:seeAlso "SNOMEDCT: 35283005; UMLS_CUI:C0310667" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_70796 ] . obo:VO_0001523 obo:IAO_0000115 "bacterial vaccine that is used to protect against Mannheimia haemolytica infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mannheimia haemolytica vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_75985 ] . obo:VO_0001524 obo:IAO_0000115 "viral vaccine that is used to protect against Porcine circovirus 2 infection" ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "porcine circovirus 2 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_85708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_85708 ] ) ] . obo:VO_0001525 obo:IAO_0000115 "viral vaccine that is used to protect against Duck enteritis virus (Anatid herpesvirus 1) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Duck enteritis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_104388 ] . obo:VO_0001526 obo:IAO_0000115 "viral vaccine that is used to protect against Canine parainfluenza virus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "canine parainfluenza virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ] ) ] . obo:VO_0001527 obo:IAO_0000115 "viral vaccine that is used to protect against Avian Paramyxovirus infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian paramyxovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_260963 ] . obo:VO_0001528 obo:IAO_0000115 "viral vaccine that is used to protect against Duck hepatitis virus 1 (Duck hepatitis A virus) infection" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Duck hepatitis virus 1 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_691956 ] . obo:VO_0001529 obo:IAO_0000117 "YL" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:comment """Vaccicel, Inc. has a location in Belton, TX. Active officers include Andre Menchu, Andres Menchu, Kathryn M Baker, Katheryn Becker and Andres Menches. Vaccicel, Inc. filed as a Domestic For-Profit Corporation on Tuesday, August 22, 1995 in the state of Texas and is currently active. Andres Menchu serves as the registered agent for this organization.The company's line of business includes Mfg Research & Development Veterinary Bacterial Vaccines. (http://www.corporationwiki.com/Texas/Belton/vaccicel-inc/34296230.aspx)""" ; rdfs:label "VacciCel, Inc." . obo:VO_0001530 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canary Pox Modified Live Virus Vaccine (USDA: 1623.10)" ; rdfs:seeAlso "USDA: 1623.10", "violinID:1557" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001517, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8825 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001531 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pigeon Pox Live Virus Vaccine (USDA: 1881.10)" ; rdfs:seeAlso "USDA: 1881.10", "violinID:2092" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001481, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8825 ] . obo:VO_0001532 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pigeon Pox Live Virus Vaccine (USDA: 1881.12)" ; rdfs:seeAlso "USDA: 1881.12", "violinID:2093" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001481, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8825 ] . obo:VO_0001533 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pigeon Pox Live Virus Vaccine (USDA: 1881.14)" ; rdfs:seeAlso "USDA: 1881.14", "violinID:2094" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001481, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8825 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001534 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Quail Pox Live Virus Vaccine (USDA: 18E1.10)" ; rdfs:seeAlso "USDA: 18E1.10", "violinID:2111" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000513, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8825 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001535 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fox Encephalitis Killed Virus Vaccine (USDA: 1635.20)" ; rdfs:seeAlso "USDA: 1635.20", "violinID:1925" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001489, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_33554 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10512 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001536 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper Modified Live Virus Vaccine (USDA: 1451.00)" ; rdfs:seeAlso "USDA: 1451.00", "violinID:1967" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_33554 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001537 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper Modified Live Virus Vaccine (USDA: 1451.01)" ; rdfs:seeAlso "USDA: 1451.01", "violinID:1968" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_33554 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001538 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper Modified Live Virus Vaccine (USDA: 1451.20)" ; rdfs:seeAlso "USDA: 1451.20", "violinID:1969" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_33554 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001539 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Enteritis Vaccine" ; rdfs:seeAlso "violinID:1972" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001493, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_33554 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10792 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001540 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline calicivirus Killed Virus Vaccine (USDA: 15C5.21)" ; rdfs:seeAlso "USDA: 15C5.21", "violinID:1766" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001509, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001541 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline calicivirus Modified Live Virus Vaccine (USDA: 15C1.22)" ; rdfs:seeAlso "USDA: 15C1.22", "violinID:1765" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001509, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001542 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline immunodeficiency virus Killed Virus Vaccine (USDA: 15A5.21)" ; rdfs:seeAlso "USDA: 15A5.21", "violinID:1767" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001508, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11673 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001543 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline immunodeficiency virus Killed Virus Vaccine (USDA: 15A5.23)" ; rdfs:seeAlso "USDA: 15A5.23", "violinID:1768" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001508, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11673 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001544 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Infectious Peritonitis Modified Live Virus Vaccine (USDA: 15A1.20)" ; rdfs:seeAlso "USDA: 15A1.20", "violinID:1771" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001504, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11135 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001545 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia Killed Virus Vaccine (USDA: 1555.20)" ; rdfs:seeAlso "USDA: 1555.20", "violinID:1772" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000843, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001546 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia Killed Virus Vaccine (USDA: 1555.21)" ; rdfs:seeAlso "USDA: 1555.21", "violinID:1773" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000843, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001547 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia Killed Virus Vaccine (USDA: 1555.22)" ; rdfs:seeAlso "USDA: 1555.22", "violinID:1774" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000843, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001548 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia Killed Virus Vaccine (USDA: 1555.R1)" ; rdfs:seeAlso "USDA: 1555.R1", "violinID:1775" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000843, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001549 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia Live Canarypox Vector Vaccine (USDA: 1555.R3)" ; rdfs:seeAlso "USDA: 1555.R3", "violinID:1776" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000843, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001550 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Panleukopenia Killed Virus Vaccine (USDA: 1565.20)" ; rdfs:seeAlso "USDA: 1565.20", "violinID:1819" ; rdfs:subClassOf obo:VO_0000389, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001551 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.00)" ; rdfs:seeAlso "USDA: 1561.00", "violinID:1815" ; rdfs:subClassOf obo:VO_0001021, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001552 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.20)" ; rdfs:seeAlso "USDA: 1561.20", "violinID:1816" ; rdfs:subClassOf obo:VO_0001021, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001553 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.21)" ; rdfs:seeAlso "USDA: 1561.21", "violinID:1817" ; rdfs:subClassOf obo:VO_0001021, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001554 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Panleukopenia Modified Live Virus Vaccine (USDA: 1561.23)" ; rdfs:seeAlso "USDA: 1561.23", "violinID:1818" ; rdfs:subClassOf obo:VO_0001021, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001555 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis Modified Live Virus Vaccine (USDA: 16A1.22)" ; rdfs:seeAlso "USDA: 16A1.22", "violinID:1820" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001487, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10334 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001556 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Edwardsiella ictaluri Avirulent Live Culture Vaccine (USDA: 1531.00)" ; rdfs:seeAlso "USDA: 1531.00", "violinID:1714" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001521, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_7995 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_67780 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001557 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Anthrax Spore live culture Vaccine (USDA: 1011.00)" ; rdfs:seeAlso "USDA: 1011.00", "violinID:1122" ; rdfs:subClassOf obo:VO_0000013, obo:VO_0000367, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001558 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1095.20)" ; rdfs:seeAlso "USDA: 1095.20", "violinID:1179" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001507, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0001559 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1095.21)" ; rdfs:seeAlso "USDA: 1095.21", "violinID:1180" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001507, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001560 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Respiratory Syncytial Virus Vaccine Modified Live Virus (USDA: 1091.20)" ; rdfs:seeAlso "USDA: 1091.20", "violinID:1178" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001507, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0001561 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Killed Virus Vaccine (USDA: 1105.20)" ; rdfs:seeAlso "USDA: 1105.20", "violinID:1186" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000987, obo:VO_0001482, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001562 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.00)" ; rdfs:seeAlso "USDA: 1101.00", "violinID:1181" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000987, obo:VO_0001482, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0001563 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.20)" ; rdfs:seeAlso "USDA: 1101.20", "violinID:1182" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000987, obo:VO_0001482, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0001564 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.21)" ; rdfs:seeAlso "USDA: 1101.21", "violinID:1183" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000987, obo:VO_0001482, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001565 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.22)" ; rdfs:seeAlso "USDA: 1101.22", "violinID:1184" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000987, obo:VO_0001482, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001566 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine (USDA: 1101.B0)" ; rdfs:seeAlso "USDA: 1101.B0", "violinID:1185" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000987, obo:VO_0001482, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000059 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001567 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.00)" ; rdfs:seeAlso "USDA: 1205.00", "violinID:1354" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001568 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.20)" ; rdfs:seeAlso "USDA: 1205.20", "violinID:1355" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ] . obo:VO_0001569 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.21)" ; rdfs:seeAlso "USDA: 1205.21", "violinID:1356" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ] . obo:VO_0001570 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.22)" ; rdfs:seeAlso "USDA: 1205.22", "violinID:1357" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001571 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine (USDA: 1205.25)" ; rdfs:seeAlso "USDA: 1205.25", "violinID:1358" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001572 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.00)" ; rdfs:seeAlso "USDA: 1201.00", "violinID:1351" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ] . obo:VO_0001573 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.20)" ; rdfs:seeAlso "USDA: 1201.20", "violinID:1352" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ] . obo:VO_0001574 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Modified Live Virus Vaccine (USDA: 1201.22)" ; rdfs:seeAlso "USDA: 1201.22", "violinID:1353" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001575 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella Abortus Strain 19, Live Culture Vaccine (USDA: 1251.01)" ; rdfs:seeAlso "USDA: 1251.01", "violinID:1383" ; rdfs:subClassOf obo:VO_0000022, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001576 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella Abortus Strain 19, Live Culture, Reduced Dose Vaccine (USDA: 1251.02)" ; rdfs:seeAlso "USDA: 1251.02", "violinID:1384" ; rdfs:subClassOf obo:VO_0000022, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001577 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella Abortus Strain RB-51, Live Culture Vaccine (USDA: 1261.00)" ; rdfs:seeAlso "USDA: 1261.00", "violinID:1385" ; rdfs:subClassOf obo:VO_0000021, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001578 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1841.00)" ; rdfs:seeAlso "USDA: 1841.00", "violinID:2077" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001506, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001579 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1841.20)" ; rdfs:seeAlso "USDA: 1841.20", "violinID:2078" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001506, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001580 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella Choleraesuis Avirulent Live Culture Vaccine (USDA: 19A1.00)" ; rdfs:seeAlso "USDA: 19A1.00", "violinID:2121" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000768, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0001581 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella Choleraesuis Avirulent Live Culture Vaccine (USDA: 19A1.01)" ; rdfs:seeAlso "USDA: 19A1.01", "violinID:2122" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000768, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0001582 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella Dublin Live Culture Vaccine (USDA: 19D1.R0)" ; rdfs:seeAlso "USDA: 19D1.R0", "violinID:2123" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000768, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001583 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trichomonas Foetus Killed Protozoa Vaccine (USDA: 1859.00)" ; rdfs:seeAlso "USDA: 1859.00", "violinID:2143" ; rdfs:subClassOf obo:VO_0000315, obo:VO_0001457, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_56690 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001584 obo:IAO_0000117 "YL" ; obo:IAO_0000118 "Wart Vaccine (Colorado Serum)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Wart Killed Virus Vaccine (USDA: 1985.50)" ; rdfs:seeAlso "USDA: 1985.50", "violinID:2144" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0001491, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10571 ] . obo:VO_0001585 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis Killed Virus Vaccine (USDA: 1015.I0)" ; rdfs:seeAlso "USDA: 1015.I0", "violinID:1124" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001522, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_70796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000059 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001586 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.10)" ; rdfs:seeAlso "USDA: 1051.10", "violinID:1125" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001522, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_70796 ] . obo:VO_0001587 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.11)" ; rdfs:seeAlso "USDA: 1051.11", "violinID:1126" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001522, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_70796 ] . obo:VO_0001588 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.12)" ; rdfs:seeAlso "USDA: 1051.12", "violinID:1127" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001522, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_70796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001589 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H10N9 Subtype, Killed Virus Vaccine (USDA: 1057.H0)" ; rdfs:seeAlso "USDA: 1057.H0", "violinID:1147" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001590 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H2N2 Subtype, Killed Virus Vaccine (USDA: 1057.H2)" ; rdfs:seeAlso "USDA: 1057.H2", "violinID:1149" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001591 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H3N4 Subtype, Killed Virus Vaccine (USDA: 1057.H3)" ; rdfs:seeAlso "USDA: 1057.H3", "violinID:1150" ; rdfs:subClassOf obo:VO_0001024, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:VO_0000812 obo:VO_0000864 ) ] ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001592 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H4N6 Subtype, Killed Virus Vaccine (USDA: 1057.H4)" ; rdfs:seeAlso "USDA: 1057.H4", "violinID:1151" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001593 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H5N2 Subtype, Killed Virus Vaccine (USDA: 1057.H5)" ; rdfs:seeAlso "USDA: 1057.H5", "violinID:1152" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001594 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H5N9 Subtype, Killed Virus Vaccine (USDA: 1057.14)" ; rdfs:seeAlso "USDA: 1057.14", "violinID:1146" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001595 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H6N8 Subtype, Killed Virus Vaccine (USDA: 1057.H6)" ; rdfs:seeAlso "USDA: 1057.H6", "violinID:1153" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001596 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H7N2 Subtype, Killed Virus Vaccine (USDA: 10F5.12)" ; rdfs:seeAlso "USDA: 10F5.12", "violinID:1158" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001597 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H7N3 Subtype, Killed Virus Vaccine (USDA: 1057.H7)" ; rdfs:seeAlso "USDA: 1057.H7", "violinID:1154" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001598 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H7N3 Subtype, Killed Virus Vaccine (USDA: 10F5.13)" ; rdfs:seeAlso "USDA: 10F5.13", "violinID:1159" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001599 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H1N1 Subtype, Killed Virus Vaccine (USDA: 1057.H1)" ; rdfs:seeAlso "USDA: 1057.H1", "violinID:1148" ; rdfs:subClassOf obo:VO_0001024, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:VO_0000812 obo:VO_0000864 ) ] ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001600 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H5N2 Subtype, Killed Virus Vaccine (USDA: 10F5.10)" ; rdfs:seeAlso "USDA: 10F5.10", "violinID:1157" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001601 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H5N3 Subtype, Killed Virus Vaccine (USDA: 1057.R3)" ; rdfs:seeAlso "USDA: 1057.R3", "violinID:1156" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001602 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza H9N2 Subtype, Killed Virus Vaccine (USDA: 1057.H9)" ; rdfs:seeAlso "USDA: 1057.H9", "violinID:1155" ; rdfs:subClassOf obo:VO_0001024, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001603 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Paramyxovirus Type 1, Killed Virus Vaccine (USDA: 10C5.11)" ; rdfs:seeAlso "USDA: 10C5.11", "violinID:1163" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001527, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_260963 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001604 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 10C5.10)" ; rdfs:seeAlso "USDA: 10C5.10", "violinID:1162" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001527, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_260963 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001605 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Pneumovirus Modified Live Virus Vaccine (USDA: 1A31.20)" ; rdfs:seeAlso "USDA: 1A31.20", "violinID:1164" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001514, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001606 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Reovirus Killed Virus Vaccine (USDA: 1045.00)" ; rdfs:seeAlso "USDA: 1045.00", "violinID:1166" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001513, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ] . obo:VO_0001607 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Reovirus Killed Virus Vaccine (USDA: 1045.01)" ; rdfs:seeAlso "USDA: 1045.01", "violinID:1167" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001513, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001608 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Reovirus Killed Virus Vaccine (USDA: 1045.02)" ; rdfs:seeAlso "USDA: 1045.02", "violinID:1168" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001513, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ] . obo:VO_0001609 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Reovirus Killed Virus Vaccine (USDA: 1045.30)" ; rdfs:seeAlso "USDA: 1045.30", "violinID:1169" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001513, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001610 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.11)" ; rdfs:seeAlso "USDA: 1231.11", "violinID:1361" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001611 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.1M)" ; rdfs:seeAlso "USDA: 1231.1M", "violinID:1373" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001612 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.20)" ; rdfs:seeAlso "USDA: 1231.20", "violinID:1375" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001613 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.21)" ; rdfs:seeAlso "USDA: 1231.21", "violinID:1376" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001614 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Ark Type, Live Virus Vaccine (USDA: 1231.22)" ; rdfs:seeAlso "USDA: 1231.22", "violinID:1377" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001615 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Conn Type, Live Virus Vaccine (USDA: 1231.15)" ; rdfs:seeAlso "USDA: 1231.15", "violinID:1365" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001616 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Delaware Type, Modified Live Virus Vaccine (USDA: 1231.1D)" ; rdfs:seeAlso "USDA: 1231.1D", "violinID:1368" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001617 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Georgia Type, Live Virus Vaccine (USDA: 1231.1J)" ; rdfs:seeAlso "USDA: 1231.1J", "violinID:1371" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001618 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Georgia Type, Live Virus Vaccine (USDA: 1231.1L)" ; rdfs:seeAlso "USDA: 1231.1L", "violinID:1372" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001619 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass & Ark Types, Killed Virus Vaccine (USDA: 1235.15)" ; rdfs:seeAlso "USDA: 1235.15", "violinID:1382" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001620 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass & Ark Types, Live Virus Vaccine (USDA: 1231.13)" ; rdfs:seeAlso "USDA: 1231.13", "violinID:1363" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001621 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass & Conn Types, Live Virus Vaccine (USDA: 1231.14)" ; rdfs:seeAlso "USDA: 1231.14", "violinID:1364" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001622 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass & Conn Types, Live Virus Vaccine (USDA: 1231.1G)" ; rdfs:seeAlso "USDA: 1231.1G", "violinID:1370" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001623 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass & Conn Types, Live Virus Vaccine (USDA:1231.1N)" ; rdfs:seeAlso "USDA:1231.1N", "violinID:1374" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001624 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.12)" ; rdfs:seeAlso "USDA: 1231.12", "violinID:1362" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001625 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.18)" ; rdfs:seeAlso "USDA: 1231.18", "violinID:1366" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001626 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.1A)" ; rdfs:seeAlso "USDA: 1231.1A", "violinID:1367" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001627 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1231.1F)" ; rdfs:seeAlso "USDA: 1231.1F", "violinID:1369" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001628 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1232.10)" ; rdfs:seeAlso "USDA: 1232.10", "violinID:1378" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001629 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1232.15)" ; rdfs:seeAlso "USDA: 1232.15", "violinID:1379" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001630 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1233.10)" ; rdfs:seeAlso "USDA: 1233.10", "violinID:1380" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001631 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bronchitis Mass Type, Live Virus Vaccine (USDA: 1235.10)" ; rdfs:seeAlso "USDA: 1235.10", "violinID:1381" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001632 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Killed Virus Vaccine (USDA: 1275.00)" ; rdfs:seeAlso "USDA: 1275.00", "violinID:1403" ; rdfs:subClassOf obo:VO_0000960, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001633 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Killed Virus Vaccine (USDA: 1275.02)" ; rdfs:seeAlso "USDA: 1275.02", "violinID:1404" ; rdfs:subClassOf obo:VO_0000960, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001634 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Killed Virus Vaccine (USDA: 1275.20)" ; rdfs:seeAlso "USDA: 1275.20", "violinID:1405" ; rdfs:subClassOf obo:VO_0000960, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001635 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.00)" ; rdfs:seeAlso "USDA: 1271.00", "violinID:1386" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001636 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.01)" ; rdfs:seeAlso "USDA: 1271.01", "violinID:1387" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001637 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.02)" ; rdfs:seeAlso "USDA: 1271.02", "violinID:1388" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001638 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.04)" ; rdfs:seeAlso "USDA: 1271.04", "violinID:1389" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001639 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.0A)" ; rdfs:seeAlso "USDA: 1271.0A", "violinID:1390" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001640 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.10)" ; rdfs:seeAlso "USDA: 1271.10", "violinID:1391" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001641 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.11)" ; rdfs:seeAlso "USDA: 1271.11", "violinID:1392" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001642 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.12)" ; rdfs:seeAlso "USDA: 1271.12", "violinID:1393" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001643 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.13)" ; rdfs:seeAlso "USDA: 1271.13", "violinID:1394" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001644 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.16)" ; rdfs:seeAlso "USDA: 1271.16", "violinID:1396" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001645 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.17)" ; rdfs:seeAlso "USDA: 1271.17", "violinID:1397" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001646 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.18)" ; rdfs:seeAlso "USDA: 1271.18", "violinID:1398" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001647 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.19)" ; rdfs:seeAlso "USDA: 1271.19", "violinID:1399" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001648 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.40)" ; rdfs:seeAlso "USDA: 1271.40", "violinID:1400" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001649 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1271.41)" ; rdfs:seeAlso "USDA: 1271.41", "violinID:1401" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001650 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Live Virus Vaccine (USDA: 1272.00)" ; rdfs:seeAlso "USDA: 1272.00", "violinID:1402" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001651 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Modified Live VirusVaccine (USDA: 1271.15)" ; rdfs:seeAlso "USDA: 1271.15", "violinID:1395" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001652 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Standard & Variant, Killed Virus Vaccine (USDA: 12B5.01)" ; rdfs:seeAlso "USDA: 12B5.01", "violinID:1409" ; rdfs:subClassOf obo:VO_0000960, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001653 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Standard & Variant, Killed Virus Vaccine (USDA: 12B5.40)" ; rdfs:seeAlso "USDA: 12B5.40", "violinID:1410" ; rdfs:subClassOf obo:VO_0000960, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001654 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Standard & Variant, Killed Virus Vaccine (USDA: 12B5.41)" ; rdfs:seeAlso "USDA: 12B5.41", "violinID:1411" ; rdfs:subClassOf obo:VO_0000960, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001655 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Standard & Variant, Killed Virus Vaccine (USDA: 12B5.4A)" ; rdfs:seeAlso "USDA: 12B5.4A", "violinID:1412" ; rdfs:subClassOf obo:VO_0000960, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001656 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Standard & Variant, Live Virus Vaccine (USDA: 12B1.00)" ; rdfs:seeAlso "USDA: 12B1.00", "violinID:1407" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001657 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Standard & Variant, Live Virus Vaccine (USDA: 12B1.01)" ; rdfs:seeAlso "USDA: 12B1.01", "violinID:1408" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001658 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Variant, Killed Virus Vaccine (USDA: 12A5.00)" ; rdfs:seeAlso "USDA: 12A5.00", "violinID:1406" ; rdfs:subClassOf obo:VO_0000960, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001659 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease Variant, Live Virus Vaccine (USDA: 12L1.00)" ; rdfs:seeAlso "USDA: 12L1.00", "violinID:1413" ; rdfs:subClassOf obo:VO_0000961, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001660 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chicken Anemia Virus Live Virus Vaccine (USDA: 10A1.00)" ; rdfs:seeAlso "USDA: 10A1.00", "violinID:1697" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001510, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12618 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001661 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chicken Anemia Virus Live Virus Vaccine (USDA: 10A1.01)" ; rdfs:seeAlso "USDA: 10A1.01", "violinID:1698" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001510, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12618 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001662 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chicken Anemia Virus Modified Live Virus Vaccine (USDA: 10A1.10)" ; rdfs:seeAlso "USDA: 10A1.10", "violinID:1699" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001510, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12618 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001663 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.50)" ; rdfs:seeAlso "USDA: 1431.50", "violinID:1702" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000906, obo:VO_0001459, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000821 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001664 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.51)" ; rdfs:seeAlso "USDA: 1431.51", "violinID:1703" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000906, obo:VO_0001459, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001665 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.56)" ; rdfs:seeAlso "USDA: 1431.56", "violinID:1705" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000906, obo:VO_0001459, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000821 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001666 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.57)" ; rdfs:seeAlso "USDA: 1431.57", "violinID:1706" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000906, obo:VO_0001459, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001667 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.58)" ; rdfs:seeAlso "USDA: 1431.58", "violinID:1707" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000906, obo:VO_0001459, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001668 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.59)" ; rdfs:seeAlso "USDA: 1431.59", "violinID:1708" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000906, obo:VO_0001459, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001669 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidiosis Live Oocysts Vaccine (USDA: 1431.5C)" ; rdfs:seeAlso "USDA: 1431.5C", "violinID:1709" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000906, obo:VO_0001459, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001670 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidiosis Live Oocysts, Chicken Isolates Vaccine (USDA: 1431.55)" ; rdfs:seeAlso "USDA: 1431.55", "violinID:1704" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000906, obo:VO_0001459, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001671 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.01)" ; rdfs:seeAlso "USDA: 1601.01", "violinID:1903" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001488, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001672 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.02)" ; rdfs:seeAlso "USDA: 1601.02", "violinID:1904" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001488, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001673 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.11)" ; rdfs:seeAlso "USDA: 1601.11", "violinID:1905" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001488, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001674 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.13)" ; rdfs:seeAlso "USDA: 1601.13", "violinID:1906" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001488, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001675 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.14)" ; rdfs:seeAlso "USDA: 1601.14", "violinID:1907" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001488, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001676 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis Modified Live Virus Vaccine (USDA: 1601.15)" ; rdfs:seeAlso "USDA: 1601.15", "violinID:1908" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001488, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001677 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.00)" ; rdfs:seeAlso "USDA: 1621.00", "violinID:1913" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001463, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001678 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.10)" ; rdfs:seeAlso "USDA: 1621.10", "violinID:1914" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001463, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001679 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.11)" ; rdfs:seeAlso "USDA: 1621.11", "violinID:1915" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001463, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001680 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.13)" ; rdfs:seeAlso "USDA: 1621.13", "violinID:1916" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001463, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001681 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1621.14)" ; rdfs:seeAlso "USDA: 1621.14", "violinID:1917" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001463, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001682 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox Live Virus Vaccine (USDA: 1622.00)" ; rdfs:seeAlso "USDA: 1622.00", "violinID:1918" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001463, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001683 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.00)" ; rdfs:seeAlso "USDA: 16L1.00", "violinID:1945" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001684 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.04)" ; rdfs:seeAlso "USDA: 16L1.04", "violinID:1948" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001685 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotype 1, Live Virus Vaccine (USDA: 16L1.09)" ; rdfs:seeAlso "USDA: 16L1.09", "violinID:1952" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001686 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotype 2, Live Virus Vaccine (USDA: 1631.00)" ; rdfs:seeAlso "USDA: 1631.00", "violinID:1934" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001687 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1641.00)" ; rdfs:seeAlso "USDA: 1641.00", "violinID:1936" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001688 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1641.01)" ; rdfs:seeAlso "USDA: 1641.01", "violinID:1937" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001689 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1641.06)" ; rdfs:seeAlso "USDA: 1641.06", "violinID:1938" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001690 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 16L1.06)" ; rdfs:seeAlso "USDA: 16L1.06", "violinID:1949" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001691 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 1 & 2 & 3, Live Virus Vaccine (USDA: 16L1.01)" ; rdfs:seeAlso "USDA: 16L1.01", "violinID:1946" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001692 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 1 & 3, Live Herpesvirus Chimera Vaccine (USDA: 1631.R0)" ; rdfs:seeAlso "USDA: 1631.R0", "violinID:1935" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001693 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 1 & 3, Live Virus Vaccine (USDA: 16G1.02)" ; rdfs:seeAlso "USDA: 16G1.02", "violinID:1944" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001694 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 1 & 3, Live Virus Vaccine (USDA: 16L1.02)" ; rdfs:seeAlso "USDA: 16L1.02", "violinID:1947" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001695 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 1 & 3, Live Virus Vaccine (USDA: 16L1.08)" ; rdfs:seeAlso "USDA: 16L1.08", "violinID:1951" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001696 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1651.00)" ; rdfs:seeAlso "USDA: 1651.00", "violinID:1939" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001697 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1651.01)" ; rdfs:seeAlso "USDA: 1651.01", "violinID:1940" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001698 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1651.02)" ; rdfs:seeAlso "USDA: 1651.02", "violinID:1941" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001699 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1651.05)" ; rdfs:seeAlso "USDA: 1651.05", "violinID:1942" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001700 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 16G1.00)" ; rdfs:seeAlso "USDA: 16G1.00", "violinID:1943" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001701 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 16L1.07)" ; rdfs:seeAlso "USDA: 16L1.07", "violinID:1950" ; rdfs:subClassOf obo:VO_0001017, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001702 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycoplasma Gallisepticum Live Culture Vaccine (USDA: 1751.00)" ; rdfs:seeAlso "USDA: 1751.00", "violinID:1973" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000949, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001703 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycoplasma Gallisepticum Live Culture Vaccine (USDA: 1751.01)" ; rdfs:seeAlso "USDA: 1751.01", "violinID:1974" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000949, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2096 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001704 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.10)" ; rdfs:seeAlso "USDA: 1711.10", "violinID:1981" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001705 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.12)" ; rdfs:seeAlso "USDA: 1711.12", "violinID:1982" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001706 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.14)" ; rdfs:seeAlso "USDA: 1711.14", "violinID:1983" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001707 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 1711.18)" ; rdfs:seeAlso "USDA: 1711.18", "violinID:1984" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001708 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, B1 Strain, Live Virus Vaccine (USDA: 17A2.10)" ; rdfs:seeAlso "USDA: 17A2.10", "violinID:1991" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001709 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, C2 Strain, Live VirusVaccine (USDA: 17B1.10)" ; rdfs:seeAlso "USDA: 17B1.10", "violinID:1993" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001710 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.0A)" ; rdfs:seeAlso "USDA: 1721.0A", "violinID:1985" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001711 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.10)" ; rdfs:seeAlso "USDA: 1721.10", "violinID:1986" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001712 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.11)" ; rdfs:seeAlso "USDA: 1721.11", "violinID:1987" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001713 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.15)" ; rdfs:seeAlso "USDA: 1721.15", "violinID:1988" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001714 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.16)" ; rdfs:seeAlso "USDA: 1721.16", "violinID:1989" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001715 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease B1 Type, LaSota Strain, Live Virus Vaccine (USDA: 1721.17)" ; rdfs:seeAlso "USDA: 1721.17", "violinID:1990" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001716 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease Killed Virus Vaccine (USDA: 1705.10)" ; rdfs:seeAlso "USDA: 1705.10", "violinID:1977" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001222, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001717 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease Killed Virus Vaccine (USDA: 1705.11)" ; rdfs:seeAlso "USDA: 1705.11", "violinID:1978" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001222, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001718 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease Killed Virus Vaccine (USDA: 1705.13)" ; rdfs:seeAlso "USDA: 1705.13", "violinID:1979" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001222, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001719 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease Killed Virus Vaccine (USDA: 1705.15)" ; rdfs:seeAlso "USDA: 1705.15", "violinID:1980" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001222, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001720 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease VG/GA Strain, Live Virus Vaccine (USDA: 1701.10)" ; rdfs:seeAlso "USDA: 1701.10", "violinID:1976" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001721 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease VG/GA Strain, Live Virus Vaccine (USDA: 17A2.V1)" ; rdfs:seeAlso "USDA: 17A2.V1", "violinID:1992" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001722 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.01)" ; rdfs:seeAlso "USDA: 1871.01", "violinID:2087" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000620, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001723 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.02)" ; rdfs:seeAlso "USDA: 1871.02", "violinID:2088" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000620, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001724 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.03)" ; rdfs:seeAlso "USDA: 1871.03", "violinID:2089" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000620, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001725 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.04)" ; rdfs:seeAlso "USDA: 1871.04", "violinID:2090" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000620, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001726 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pasteurella Multocida Avirulent Live Culture, Avian Isolate Vaccine (USDA: 1871.05)" ; rdfs:seeAlso "USDA: 1871.05", "violinID:2091" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000620, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001727 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.00)" ; rdfs:seeAlso "USDA: 19C1.00", "violinID:2124" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0002507, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001728 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.01)" ; rdfs:seeAlso "USDA: 19C1.01", "violinID:2125" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0002507, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001729 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella Typhimurium Live Culture Vaccine (USDA: 19C1.02)" ; rdfs:seeAlso "USDA: 19C1.02", "violinID:2126" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0002507, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0001730 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tenosynovitis Live Virus Vaccine (USDA: 1951.10)" ; rdfs:seeAlso "USDA: 1951.10", "violinID:2139" ; rdfs:subClassOf obo:VO_0001019, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001731 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.01)" ; rdfs:seeAlso "USDA: 1951.01", "violinID:2135" ; rdfs:subClassOf obo:VO_0001019, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001732 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.02)" ; rdfs:seeAlso "USDA: 1951.02", "violinID:2136" ; rdfs:subClassOf obo:VO_0001019, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001733 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.03)" ; rdfs:seeAlso "USDA: 1951.03", "violinID:2137" ; rdfs:subClassOf obo:VO_0001019, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001734 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.04)" ; rdfs:seeAlso "USDA: 1951.04", "violinID:2138" ; rdfs:subClassOf obo:VO_0001019, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001735 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1951.11)" ; rdfs:seeAlso "USDA: 1951.11", "violinID:2140" ; rdfs:subClassOf obo:VO_0001019, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001736 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tenosynovitis Modified Live Virus Vaccine (USDA: 1952.01)" ; rdfs:seeAlso "USDA: 1952.01", "violinID:2141" ; rdfs:subClassOf obo:VO_0001019, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001737 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Duck Virus Enteritis Modified Live Virus Vaccine (USDA: 1461.10)" ; rdfs:seeAlso "USDA: 1461.10", "violinID:1712" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001525, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8835 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_104388 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001458 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001738 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Duck Virus Hepatitis Modified Live Virus Vaccine (USDA: 14B1.10)" ; rdfs:seeAlso "USDA: 14B1.10", "violinID:1713" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001528, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8835 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_691956 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001458 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001739 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Riemerella Anatipestifer Avirulent Live Culture Vaccine (USDA: 1811.00)" ; rdfs:seeAlso "USDA: 1811.00", "violinID:2120" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001512, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_8835 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_34085 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001458 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001740 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Flavobacterium Columnare Avirulent Live Culture Vaccine (USDA: 17F1.00)" ; rdfs:seeAlso "USDA: 17F1.00", "violinID:1902" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000637, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_117565 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001741 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella Bronchiseptica Avirulent Live Culture Vaccine (USDA: 1081.00)" ; rdfs:seeAlso "USDA: 1081.00", "violinID:1172" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000394, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0001742 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella Bronchiseptica Avirulent Live Culture Vaccine (USDA: 1081.01)" ; rdfs:seeAlso "USDA: 1081.01", "violinID:1173" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000394, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0001743 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine (USDA: 14P5.20)" ; rdfs:seeAlso "USDA: 14P5.20", "violinID:1562" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000932, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ] . obo:VO_0001744 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine (USDA: 14P5.21)" ; rdfs:seeAlso "USDA: 14P5.21", "violinID:1563" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000932, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001745 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Modified Live Virus Vaccine (USDA: 14P1.20)" ; rdfs:seeAlso "USDA: 14P1.20", "violinID:1561" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000932, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001746 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Influenza H3N8, Killed Virus Vaccine (USDA: 15K5.20)" ; rdfs:seeAlso "USDA: 15K5.20", "violinID:1691" ; rdfs:subClassOf obo:VO_0000954, obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001747 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Parainfluenza Modified Live Virus Vaccine (USDA: 1421.21)" ; rdfs:seeAlso "USDA: 1421.21", "violinID:1692" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001526, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001748 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Distemper Live Canarypox Vector Vaccine (USDA: 1471.R0)" ; rdfs:seeAlso "USDA: 1471.R0", "violinID:1711" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001749 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Distemper Modified Live Virus Vaccine (USDA: 1471.10)" ; rdfs:seeAlso "USDA: 1471.10", "violinID:1710" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001750 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Giardia Lamblia Killed Protozoa Vaccine (USDA: 18G5.00)" ; rdfs:seeAlso "USDA: 18G5.00", "violinID:1926" ; rdfs:subClassOf obo:VO_0000315, obo:VO_0001083, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5741 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001751 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neospora Caninum Killed Protozoa Vaccine (USDA: 1N11.00)" ; rdfs:seeAlso "USDA: 1N11.00", "violinID:1975" ; rdfs:subClassOf obo:VO_0000315, obo:VO_0001065, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001752 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine (USDA: 18P5.20)" ; rdfs:seeAlso "USDA: 18P5.20", "violinID:2085" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001753 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine (USDA: 18P5.21)" ; rdfs:seeAlso "USDA: 18P5.21", "violinID:2086" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001754 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.20)" ; rdfs:seeAlso "USDA: 18M1.20", "violinID:2079" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0001755 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.21)" ; rdfs:seeAlso "USDA: 18M1.21", "violinID:2080" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001756 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.22)" ; rdfs:seeAlso "USDA: 18M1.22", "violinID:2081" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001757 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.23)" ; rdfs:seeAlso "USDA: 18M1.23", "violinID:2082" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001758 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.25)" ; rdfs:seeAlso "USDA: 18M1.25", "violinID:2083" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001759 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Modified Live Virus Vaccine (USDA: 18M1.29)" ; rdfs:seeAlso "USDA: 18M1.29", "violinID:2084" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001760 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.20)" ; rdfs:seeAlso "USDA: 1905.20", "violinID:2115" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0001761 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.21)" ; rdfs:seeAlso "USDA: 1905.21", "violinID:2116" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0001762 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.22)" ; rdfs:seeAlso "USDA: 1905.22", "violinID:2117" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001763 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.23)" ; rdfs:seeAlso "USDA: 1905.23", "violinID:2118" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0001764 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Killed Virus Vaccine (USDA: 1905.24)" ; rdfs:seeAlso "USDA: 1905.24", "violinID:2119" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0001765 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Live Canarypox Vector Vaccine (USDA: 1901.R1)" ; rdfs:seeAlso "USDA: 1901.R1", "violinID:2113" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000650, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001766 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Live Canarypox Vector Vaccine (USDA: 1901.R6)" ; rdfs:seeAlso "USDA: 1901.R6", "violinID:2114" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000650, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001767 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Live Vaccinia Vector Vaccine (USDA: 1901.R0)" ; rdfs:seeAlso "USDA: 1901.R0", "violinID:2112" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000650, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001768 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Arteritis Modified Live Virus Vaccine (USDA: 1531.20)" ; rdfs:seeAlso "USDA: 1531.20", "violinID:1731" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001500, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001769 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Killed Virus Vaccine (USDA: 1505.10)" ; rdfs:seeAlso "USDA: 1505.10", "violinID:1735" ; rdfs:subClassOf obo:VO_0000460, obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000264 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001770 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Killed Virus Vaccine (USDA: 1505.20)" ; rdfs:seeAlso "USDA: 1505.20", "violinID:1736" ; rdfs:subClassOf obo:VO_0000460, obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001771 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Killed Virus Vaccine (USDA: 1505.21)" ; rdfs:seeAlso "USDA: 1505.21", "violinID:1737" ; rdfs:subClassOf obo:VO_0000460, obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001772 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Killed Virus Vaccine (USDA: 1505.24)" ; rdfs:seeAlso "USDA: 1505.24", "violinID:1738" ; rdfs:subClassOf obo:VO_0000460, obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001773 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Killed Virus Vaccine (USDA: 1505.25)" ; rdfs:seeAlso "USDA: 1505.25", "violinID:1739" ; rdfs:subClassOf obo:VO_0000460, obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001774 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Killed Virus Vaccine (USDA: 1505.28)" ; rdfs:seeAlso "USDA: 1505.28", "violinID:1740" ; rdfs:subClassOf obo:VO_0000460, obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001775 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Live Canarypox Vector Vaccine (USDA: 1501.R0)" ; rdfs:seeAlso "USDA: 1501.R0", "violinID:1734" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000460, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:VO_0000812 obo:VO_0000864 ) ] ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001776 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Modified Live Virus Vaccine (USDA: 1501.10)" ; rdfs:seeAlso "USDA: 1501.10", "violinID:1732" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000460, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001777 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Influenza Modified Live Virus Vaccine (USDA: 1501.20)" ; rdfs:seeAlso "USDA: 1501.20", "violinID:1733" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000460, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001778 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.20)" ; rdfs:seeAlso "USDA: 1525.20", "violinID:1742" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001486, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001779 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.21)" ; rdfs:seeAlso "USDA: 1525.21", "violinID:1743" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001486, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ] . obo:VO_0001780 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.22)" ; rdfs:seeAlso "USDA: 1525.22", "violinID:1744" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001486, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001781 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis Killed Virus Vaccine (USDA: 1525.24)" ; rdfs:seeAlso "USDA: 1525.24", "violinID:1745" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001486, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001782 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis Modified Live Virus Vaccine (USDA: 1521.20)" ; rdfs:seeAlso "USDA: 1521.20", "violinID:1741" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001486, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001783 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rotavirus Killed Virus Vaccine (USDA: 1E15.20)" ; rdfs:seeAlso "USDA: 1E15.20", "violinID:1756" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001496, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001784 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus Equi Live Culture Vaccine (USDA: 1831.00)" ; rdfs:seeAlso "USDA: 1831.00", "violinID:2127" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000948, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001785 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Polyomavirus Killed Virus Vaccine (USDA: 1A15.00)" ; rdfs:seeAlso "USDA: 1A15.00", "violinID:1165" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001492, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9224 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001786 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamydia Psittaci Killed Chlamydia Vaccine (USDA: 1585.20)" ; rdfs:seeAlso "USDA: 1585.20", "violinID:1701" ; rdfs:subClassOf obo:VO_0001214, obo:VO_0001485, obo:VO_0012174, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9224 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001787 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamydia Psittaci Modified Live Chlamydia Vaccine (USDA: 1581.20)" ; rdfs:seeAlso "USDA: 1581.20", "violinID:1700" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0012174, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9224 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001788 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pacheco's Disease Killed Virus Vaccine (USDA: 18C5.00)" ; rdfs:seeAlso "USDA: 18C5.00", "violinID:2076" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001518, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9224 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001789 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.00)" ; rdfs:seeAlso "USDA: 1541.00", "violinID:1757" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001456, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ] . obo:VO_0001790 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.01)" ; rdfs:seeAlso "USDA: 1541.01", "violinID:1758" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001456, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ] . obo:VO_0001791 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.02)" ; rdfs:seeAlso "USDA: 1541.02", "violinID:1759" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001456, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000265 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001792 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.03)" ; rdfs:seeAlso "USDA: 1541.03", "violinID:1760" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001456, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000265 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001793 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Erysipelothrix Rhusiopathiae Avirulent Live Culture Vaccine (USDA: 1541.04)" ; rdfs:seeAlso "USDA: 1541.04", "violinID:1761" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001456, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000265 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001794 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus Parasuis Avirulent Live Culture Vaccine (USDA: 19J1.00)" ; rdfs:seeAlso "USDA: 19J1.00", "violinID:1927" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000611, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000268 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001795 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.00)" ; rdfs:seeAlso "USDA: 10L1.00", "violinID:1929" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001105, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29546 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001796 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.01)" ; rdfs:seeAlso "USDA: 10L1.01", "violinID:1930" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001105, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29546 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001797 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lawsonia Intracellularis Avirulent Live Culture Vaccine (USDA: 10L1.02)" ; rdfs:seeAlso "USDA: 10L1.02", "violinID:1931" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001105, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29546 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001798 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Circovirus Type 2, Killed Virus Vaccine (USDA: 19K5.20)" ; rdfs:seeAlso "USDA: 19K5.20", "violinID:2095" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001524, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001799 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome Reproductive & Respiratory Form, Modified Live Virus Vaccine (USDA: 19T1.20)" ; rdfs:seeAlso "USDA: 19T1.20", "violinID:2102" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001511, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001800 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome Reproductive & Respiratory Form, Modified Live Virus Vaccine (USDA: 19T1.21)" ; rdfs:seeAlso "USDA: 19T1.21", "violinID:2103" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001511, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001801 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome Reproductive Form, Killed Virus Vaccine (USDA: 19S5.20)" ; rdfs:seeAlso "USDA: 19S5.20", "violinID:2101" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001511, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001802 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome Reproductive Form, Modified Live Virus Vaccine (USDA: 19Q1.20)" ; rdfs:seeAlso "USDA: 19Q1.20", "violinID:2098" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001511, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001803 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine (USDA: 19S1.20)" ; rdfs:seeAlso "USDA: 19S1.20", "violinID:2099" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001511, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001804 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine (USDA: 19S1.21)" ; rdfs:seeAlso "USDA: 19S1.21", "violinID:2100" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001511, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001805 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus Modified Live Virus Vaccine (USDA: 19E1.20)" ; rdfs:seeAlso "USDA: 19E1.20", "violinID:2104" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001495, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001806 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies Modified Live Virus Vaccine (USDA: 1891.20)" ; rdfs:seeAlso "USDA: 1891.20", "violinID:2107" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000750, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ] . obo:VO_0001807 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies Modified Live Virus Vaccine (USDA: 1891.22)" ; rdfs:seeAlso "USDA: 1891.22", "violinID:2108" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000750, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001808 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies Modified Live Virus Vaccine (USDA: 1891.R2)" ; rdfs:seeAlso "USDA: 1891.R2", "violinID:2109" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000750, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001809 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies Modified Live Virus Vaccine (USDA: 1891.R4)" ; rdfs:seeAlso "USDA: 1891.R4", "violinID:2110" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000750, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001810 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza pH1N1, Killed Virus Vaccine (USDA: 19A5.2P)" ; rdfs:seeAlso "USDA: 19A5.2P", "violinID:2134" ; rdfs:subClassOf obo:VO_0000578, obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001811 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Transmissible Gastroenteritis Modified Live Virus Vaccine (USDA: 1961.20)" ; rdfs:seeAlso "USDA: 1961.20", "violinID:2142" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001505, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11149 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001812 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "West Nile Virus Killed Virus Vaccine (USDA: 1995.20)" ; rdfs:seeAlso "USDA: 1995.20", "violinID:2147" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000752, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9768 ] . obo:VO_0001813 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "West Nile Virus Killed Virus Vaccine (USDA: 1995.22)" ; rdfs:seeAlso "USDA: 1995.22", "violinID:2148" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0000752, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9768 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001814 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "West Nile Virus Live Canarypox Vector Vaccine (USDA: 1991.R0)" ; rdfs:seeAlso "USDA: 1991.R0", "violinID:2145" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000752, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9768 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001815 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "West Nile Virus Live Flavivirus Chimera Vaccine (USDA: 1991.R1)" ; rdfs:seeAlso "USDA: 1991.R1", "violinID:2146" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000752, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9768 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001816 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bluetongue Modified Live Virus Vaccine (USDA: 1061.00)" ; rdfs:seeAlso "USDA: 1061.00", "violinID:1170" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0001515, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9940 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001817 obo:IAO_0000117 "YH" ; obo:IAO_0000119 "WEB: https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM518295.pdf", "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5554" ; obo:VO_0001818 "5554" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Afluria Quadrivalent" ; rdfs:label "Afluria Quadrivalent" ; rdfs:seeAlso "CVX: 150" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000917 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000689 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:VO_0000908 ] . obo:VO_0001818 obo:IAO_0000115 "An annotation property that represents a matched vaccine identifier used in the VIOLIN database." ; obo:IAO_0000117 "Oliver He", "Omar Tibi" ; a owl:AnnotationProperty ; rdfs:label "VIOLIN vaccine ID" . obo:VO_0001819 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Arthrobacter Live Culture Vaccine (USDA: 1K11.00)" ; rdfs:seeAlso "USDA: 1K11.00", "violinID:1123" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001151, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_504568 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001820 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella Avium Avirulent Live Culture Vaccine (USDA: 1021.01)" ; rdfs:seeAlso "USDA: 1021.01", "violinID:1171" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001114, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9103 ] . obo:VO_0001821 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Escherichia coli avirulent live culture vaccine (USDA: 1551.02)" ; rdfs:seeAlso "USDA: 1551.02", "violinID:1762" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000962, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9103 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_562 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000265 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001822 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Escherichia coli avirulent live culture vaccine (USDA: 15R1.00)" ; rdfs:seeAlso "USDA: 15R1.00", "violinID:1764" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000619, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9103 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83334 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000265 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001823 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Escherichia coli live culture vaccine (USDA: 1551.R0)" ; rdfs:seeAlso "USDA: 1551.R0", "violinID:1763" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000619, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9103 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83334 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001824 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hemorrhagic Enteritis Live Virus Vaccine (USDA: 17E1.20)" ; rdfs:seeAlso "USDA: 17E1.20", "violinID:1928" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0001516, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9103 ] . obo:VO_0001825 obo:IAO_0000117 "YL" ; oboInOwl:hasAlternativeId "VO:0002194" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine (USDA: 19K5.R0)" ; rdfs:seeAlso "USDA: 19K5.R0", "violinID:2096" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001524, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001826 obo:IAO_0000117 "YL" ; oboInOwl:hasAlternativeId "VO:0002187" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.12)" ; rdfs:seeAlso "USDA: 19A5.12", "violinID:2128" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002477, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001827 obo:IAO_0000117 "YL" ; oboInOwl:hasAlternativeId "VO:0002188" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.22)" ; rdfs:seeAlso "USDA: 19A5.22", "violinID:2129" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002477, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ] . obo:VO_0001828 obo:IAO_0000117 "YL" ; oboInOwl:hasAlternativeId "VO:0002189" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.23)" ; rdfs:seeAlso "USDA: 19A5.23", "violinID:2130" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002477, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001829 obo:IAO_0000117 "YL" ; oboInOwl:hasAlternativeId "VO:0002190" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.24)" ; rdfs:seeAlso "USDA: 19A5.24", "violinID:2131" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002477, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ] . obo:VO_0001830 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:hasAlternativeId "VO:0002191" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.26)" ; rdfs:seeAlso "USDA: 19A5.26", "violinID:2132" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002477, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001831 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:hasAlternativeId "VO:0002192" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.29)" ; rdfs:seeAlso "USDA: 19A5.29", "violinID:2133" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002477, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001832 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper-Enteritis Modified Live & Killed Virus Vaccine (USDA: 1679.31)" ; rdfs:seeAlso "USDA: 1679.31", "violinID:1970;1971" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002484, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001833 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper-Enteritis Modified Live & Killed Virus Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid (USDA: 4929.31)" ; rdfs:seeAlso "USDA: 4929.31", "violinID:2884;2885;2886" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002449, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001834 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper-Enteritis Modified Live & Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 4949.20)" ; rdfs:seeAlso "USDA: 4949.20", "violinID:2887;28882889;2890" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002450, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001835 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper-Enteritis Modified Live & Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 4949.31)" ; rdfs:seeAlso "USDA: 4949.31", "violinID:2891;2892;2893;2894" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002450, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001836 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper-Enteritis Modified Live Virus & Killed Virus Vaccine-Clostridium botulinum Type C Bacterin-Toxoid (USDA: 4929.20)" ; rdfs:seeAlso "USDA: 4929.20", "violinID:2881;2882;2883" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002449, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001837 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C Bacterin-Toxoid (USDA: 4955.20)" ; rdfs:seeAlso "USDA: 4955.20", "violinID:2895;2896" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002449, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001838 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C Bacterin-Toxoid (USDA: 4955.21)" ; rdfs:seeAlso "USDA: 4955.21", "violinID:2897;2898" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002451, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001839 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 49A5.20)" ; rdfs:seeAlso "USDA: 49A5.20", "violinID:2899;2900;2901" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002452, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001840 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Enteritis Killed Virus Vaccine-Clostridium botulinum Type C-Pseudomonas aeruginosa Bacterin-Toxoid (USDA: 49A5.21)" ; rdfs:seeAlso "USDA: 49A5.21", "violinID:2902;2903;2904" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002452, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000056 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001841 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Immunodeficiency-Leukemia Virus Killed Virus Vaccine (USDA: 15D5.R0)" ; rdfs:seeAlso "USDA: 15D5.R0", "violinID:1769;1770" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002427, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001842 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1A69.20)" ; rdfs:seeAlso "USDA: 1A69.20", "violinID:1777;1778" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002432, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001843 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 15B5.20)" ; rdfs:seeAlso "USDA: 15B5.20", "violinID:1779;1780;1781;1782" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002433, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001844 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 15B5.21)" ; rdfs:seeAlso "USDA: 15B5.21", "violinID:1783;1784;1785;1786" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002433, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001845 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 15B9.20)" ; rdfs:seeAlso "USDA: 15B9.20", "violinID:1787;1788;1789;1790" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002433, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001846 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 15B9.21)" ; rdfs:seeAlso "USDA: 15B9.21", "violinID:1791;1792;1793;1794" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002433, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001847 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.20)" ; rdfs:seeAlso "USDA: 1559.20", "violinID:1795;1796;1797;1798;1799" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002434, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001848 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.23)" ; rdfs:seeAlso "USDA: 1559.23", "violinID:1800;1801;1802;1803;1804" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002434, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001849 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live & Killed Virus, Killed Chlamydia Vaccine (USDA: 1559.2C)" ; rdfs:seeAlso "USDA: 1559.2C", "violinID:1810;1811;1812;1813;1814" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002434, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001850 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live & Killed Virus, Modified Live Chlamydia Vaccine (USDA: 1559.2B)" ; rdfs:seeAlso "USDA: 1559.2B", "violinID:1805;1806;1807;1808;1809" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002434, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001851 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16F1.20)" ; rdfs:seeAlso "USDA: 16F1.20", "violinID:1821;1822;1823" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002435, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001852 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16F1.21)" ; rdfs:seeAlso "USDA: 16F1.21", "violinID:1824;1825;1826" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002435, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001853 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 16D5.20)" ; rdfs:seeAlso "USDA: 16D5.20", "violinID:1839;1840;1841" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001854 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Killed Virus Vaccine (USDA: 16D5.23)" ; rdfs:seeAlso "USDA: 16D5.23", "violinID:1842;1843;1844" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001855 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live & Killed Virus Vaccine (USDA: 16D9.20)" ; rdfs:seeAlso "USDA: 16D9.20", "violinID:1851;1852;1853" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001856 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.20)" ; rdfs:seeAlso "USDA: 16D1.20", "violinID:1827;1828;1829" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001857 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.22)" ; rdfs:seeAlso "USDA: 16D1.22", "violinID:1830;1831;1832" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001858 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.23)" ; rdfs:seeAlso "USDA: 16D1.23", "violinID:1833;1834;1835" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001859 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D1.24)" ; rdfs:seeAlso "USDA: 16D1.24", "violinID:1836;1837;1838" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001860 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D8.20)" ; rdfs:seeAlso "USDA: 16D8.20", "violinID:1845;1846;1847" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001861 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Modified Live Virus Vaccine (USDA: 16D8.21)" ; rdfs:seeAlso "USDA: 16D8.21", "violinID:1848;1849;1850" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001862 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 16E5.20)" ; rdfs:seeAlso "USDA: 16E5.20", "violinID:1862;1863;18641865" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002437, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001863 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Killed Virus, Killed Chlamydia Vaccine (USDA: 16E5.23)" ; rdfs:seeAlso "USDA: 16E5.23", "violinID:1866;1867;1868;1869" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002437, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001864 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Killed Chlamydia Vaccine (USDA: 16E6.20)" ; rdfs:seeAlso "USDA: 16E6.20", "violinID:1870;1871;1872;1873" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002437, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001865 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E1.20)" ; rdfs:seeAlso "USDA: 16E1.20", "violinID:1854;1855;1856;1857" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002437, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001866 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E1.24)" ; rdfs:seeAlso "USDA: 16E1.24", "violinID:1858;1859;1860;1861" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002437, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001867 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Modified Live Virus, Modified Live Chlamydia Vaccine (USDA: 16E8.20)" ; rdfs:seeAlso "USDA: 16E8.20", "violinID:1874;1875;1876;1877" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002437, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001868 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Modified Live & Killed Virus, Modified Live Chlamydia Vaccine (USDA: 1619.20)" ; rdfs:seeAlso "USDA: 1619.20", "violinID:1878;1879;1880;1881" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002438, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001869 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Modified Live Virus and Chlamydia, Canarypox Vector Vaccine (USDA: 1619.R1)" ; rdfs:seeAlso "USDA: 1619.R1", "violinID:1883;18841885;1886;1887" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002438, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001870 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Modified Live & Killed Virus Vaccine (USDA: 16T9.20)" ; rdfs:seeAlso "USDA: 16T9.20", "violinID:1888;1889;1890;1891" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002439, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001871 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Modified Live Virus, Canarypox Vector Vaccine (USDA: 16T9.R0)" ; rdfs:seeAlso "USDA: 16T9.R0", "violinID:1892;1893;1894;1895" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002439, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001872 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calicivirus Modified Live Virus Vaccine (USDA: 16C1.20)" ; rdfs:seeAlso "USDA: 16C1.20", "violinID:1896;1897" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002440, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001873 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calicivirus Modified Live Virus Vaccine (USDA: 16C1.21)" ; rdfs:seeAlso "USDA: 16C1.21", "violinID:1898;1899" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002440, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001874 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calicivirus Modified Live Virus Vaccine (USDA: 16C1.22)" ; rdfs:seeAlso "USDA: 16C1.22", "violinID:1899;1900" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002440, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001875 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1161.00)" ; rdfs:seeAlso "USDA: 1161.00", "violinID:1174;1175" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002330, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001876 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1161.20)" ; rdfs:seeAlso "USDA: 1161.20", "violinID:1176;1177" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002330, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001877 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45H5.20)" ; rdfs:seeAlso "USDA: 45H5.20", "violinID:2152;2153;2154;2155" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002331, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000058 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001878 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45H5.21)" ; rdfs:seeAlso "USDA: 45H5.21", "violinID:2156;2157;2158;2159" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002331, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000058 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001879 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid (USDA: 4109.20)" ; rdfs:seeAlso "USDA: 4109.20", "violinID:2160;2161;2162;2163;2164" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002332, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000058 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001880 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4019.00)" ; rdfs:seeAlso "USDA: 4019.00", "violinID:2165;2166" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002333, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001881 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4059.00)" ; rdfs:seeAlso "USDA: 4059.00", "violinID:2167;2168" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002334, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001882 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Hardjo-Pomona Bacterin (USDA: 4069.20)" ; rdfs:seeAlso "USDA: 4069.20", "violinID:2169;2170" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002335, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001883 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4089.00)" ; rdfs:seeAlso "USDA: 4089.00", "violinID:2171;2172" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002336, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001884 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4089.20)" ; rdfs:seeAlso "USDA: 4089.20", "violinID:2173;2174" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002336, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001885 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Killed Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin (USDA: 4265.00)" ; rdfs:seeAlso "USDA: 4265.00", "violinID:2187;2188;2189;2190" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002337, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001886 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.00)" ; rdfs:seeAlso "USDA: 1121.00", "violinID:1187;1188" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002338, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001887 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.20)" ; rdfs:seeAlso "USDA: 1121.20", "violinID:1189;1190" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002338, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001888 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.21)" ; rdfs:seeAlso "USDA: 1121.21", "violinID:1191;1192" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002338, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001889 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.24)" ; rdfs:seeAlso "USDA: 1121.24", "violinID:1193;1194" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002338, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001890 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1121.31)" ; rdfs:seeAlso "USDA: 1121.31", "violinID:1195;1196" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002338, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001891 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 4139.20)" ; rdfs:seeAlso "USDA: 4139.20", "violinID:2175;2176;2177" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002339, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001892 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4129.00)" ; rdfs:seeAlso "USDA: 4129.00", "violinID:2178;2179;2180" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002340, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001893 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4179.00)" ; rdfs:seeAlso "USDA: 4179.00", "violinID:2181;2182;2183" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002341, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001894 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4209.00)" ; rdfs:seeAlso "USDA: 4209.00", "violinID:2184;2185;2186" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002342, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001895 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.00)" ; rdfs:seeAlso "USDA: 1071.00", "violinID:1197;1198;1199" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002343, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001896 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.20)" ; rdfs:seeAlso "USDA: 1071.20", "violinID:1200;1201;1202" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002343, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001897 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.21)" ; rdfs:seeAlso "USDA: 1071.21", "violinID:1203;1204;1205" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002343, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001898 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.22)" ; rdfs:seeAlso "USDA: 1071.22", "violinID:1206;1207;1208" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002343, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001899 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1071.23)" ; rdfs:seeAlso "USDA: 1071.23", "violinID:1209;1210;1211" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002343, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001900 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 11B5.20)" ; rdfs:seeAlso "USDA: 11B5.20", "violinID:1213;1214" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002344, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001901 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine (USDA: 1155.20)" ; rdfs:seeAlso "USDA: 1155.20", "violinID:1224;1225" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001902 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine (USDA: 1155.30)" ; rdfs:seeAlso "USDA: 1155.30", "violinID:1226;1227" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001903 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4145.20)" ; rdfs:seeAlso "USDA: 4145.20", "violinID:2195;2196;2197;2198" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002346, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001904 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4145.21)" ; rdfs:seeAlso "USDA: 4145.21", "violinID:2199;2200;2201;2202" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002346, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001905 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 43S5.20)" ; rdfs:seeAlso "USDA: 43S5.20", "violinID:2203;22042205;2206;2207" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002347, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000058 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001906 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid (USDA: 43T5.20)" ; rdfs:seeAlso "USDA: 43T5.20", "violinID:2208;2209;2210;2211;2212;2213" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002348, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000058 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001907 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4335.20)" ; rdfs:seeAlso "USDA: 4335.20", "violinID:2214;2215;2216" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002349, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001908 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4336.30)" ; rdfs:seeAlso "USDA: 4336.30", "violinID:2217;2218;2219" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002349, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001909 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.00)" ; rdfs:seeAlso "USDA: 1151.00", "violinID:1214;1215" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001910 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.20)" ; rdfs:seeAlso "USDA: 1151.20", "violinID:1216;1217" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001911 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.22)" ; rdfs:seeAlso "USDA: 1151.22", "violinID:1218;1219" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001912 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.23)" ; rdfs:seeAlso "USDA: 1151.23", "violinID:1220;1221" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001913 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine (USDA: 1151.26)" ; rdfs:seeAlso "USDA: 1151.26", "violinID:1222;1223" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001914 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4141.20)" ; rdfs:seeAlso "USDA: 4141.20", "violinID:2191;2192;2193;2194" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002346, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001915 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4339.00)" ; rdfs:seeAlso "USDA: 4339.00", "violinID:2220;2221;2222" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002349, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001916 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4359.00)" ; rdfs:seeAlso "USDA: 4359.00", "violinID:2223;2224;2225" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002350, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001917 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Hardjo-Pomona Bacterin (USDA: 4399.20)" ; rdfs:seeAlso "USDA: 4399.20", "violinID:2226;2227;2228" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002351, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001918 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.00)" ; rdfs:seeAlso "USDA: 4389.00", "violinID:2229;2230;2231" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002352, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001919 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.20)" ; rdfs:seeAlso "USDA: 4389.20", "violinID:2232;2233;2234" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002352, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001920 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4389.21)" ; rdfs:seeAlso "USDA: 4389.21", "violinID:2235;2236;2237" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002352, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001921 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Killed Virus Vaccine (USDA: 1175.20)" ; rdfs:seeAlso "USDA: 1175.20", "violinID:1252;1253;1254" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001922 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4435.20)" ; rdfs:seeAlso "USDA: 4435.20", "violinID:2252;2253;2254;2255" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002349, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001923 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.00)" ; rdfs:seeAlso "USDA: 1171.00", "violinID:1228;1229;1230" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001924 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.20)" ; rdfs:seeAlso "USDA: 1171.20", "violinID:1231;1232;1233" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001925 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.22)" ; rdfs:seeAlso "USDA: 1171.22", "violinID:1234;1235;1236" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001926 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.24)" ; rdfs:seeAlso "USDA: 1171.24", "violinID:1237;1238;1239" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001927 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.25)" ; rdfs:seeAlso "USDA: 1171.25", "violinID:1240;1241;1242" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001928 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.26)" ; rdfs:seeAlso "USDA: 1171.26", "violinID:1243;1244;1245" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001929 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.27)" ; rdfs:seeAlso "USDA: 1171.27", "violinID:1246;1247;1248" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001930 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine (USDA: 1171.30)" ; rdfs:seeAlso "USDA: 1171.30", "violinID:1249;1250;1251" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002353, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001931 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4560.24)" ; rdfs:seeAlso "USDA: 4560.24", "violinID:2238;2239;2240;2241" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002354, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001932 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4560.25)" ; rdfs:seeAlso "USDA: 4560.25", "violinID:2242;2243;2244;2245" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002354, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001933 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Haemophilus somnus-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4489.30)" ; rdfs:seeAlso "USDA: 4489.30", "violinID:2246;2247;2248;2249;2250;2251" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002490, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001934 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4439.00)" ; rdfs:seeAlso "USDA: 4439.00", "violinID:2256;2257;2258;2259" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002355, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001935 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4439.20)" ; rdfs:seeAlso "USDA: 4439.20", "violinID:2260;2261;2262;2263" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002355, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001936 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin (USDA: 4479.00)" ; rdfs:seeAlso "USDA: 4479.00", "violinID:2264;2265;2266;2267" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002356, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001937 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4509.00)" ; rdfs:seeAlso "USDA: 4509.00", "violinID:2268;2269;2270;2271" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002488, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001938 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Mannheimia Haemolytica Bacterin (USDA: 44A5.20)" ; rdfs:seeAlso "USDA: 44A5.20", "violinID:2486;2487;2488;2489" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002357, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001939 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.00)" ; rdfs:seeAlso "USDA: 1181.00", "violinID:1255;1256;1257;1258" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001940 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.20)" ; rdfs:seeAlso "USDA: 1181.20", "violinID:1259;1260;1261;1262" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001941 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.21)" ; rdfs:seeAlso "USDA: 1181.21", "violinID:1263;1263;1265;1266" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001942 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.22)" ; rdfs:seeAlso "USDA: 1181.22", "violinID:1267;1268;1269;1270" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001943 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.23)" ; rdfs:seeAlso "USDA: 1181.23", "violinID:1271;1272;1273;1274" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001944 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.24)" ; rdfs:seeAlso "USDA: 1181.24", "violinID:1275;1276;1277;1278" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001945 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.25)" ; rdfs:seeAlso "USDA: 1181.25", "violinID:1279;1280;1281;1282" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001946 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.26)" ; rdfs:seeAlso "USDA: 1181.26", "violinID:1283;1284;1285;1286" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001947 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.28)" ; rdfs:seeAlso "USDA: 1181.28", "violinID:1287;1288;1289;1290" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001948 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 1181.30)" ; rdfs:seeAlso "USDA: 1181.30", "violinID:1291;1292;1293;1294" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001949 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1185.20)" ; rdfs:seeAlso "USDA: 1185.20", "violinID:1295;1296;1297;1298" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001950 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 1185.22)" ; rdfs:seeAlso "USDA: 1185.22", "violinID:1299;1300;1301;1302" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001951 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44M5.20)" ; rdfs:seeAlso "USDA: 44M5.20", "violinID:2277;2278;2279;2280;2281;2282" ; rdfs:subClassOf obo:VO_0002359, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001952 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44M5.22)" ; rdfs:seeAlso "USDA: 44M5.22", "violinID:2283;2284;2285;2286;2287;2288" ; rdfs:subClassOf obo:VO_0002359, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001953 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B5.20)" ; rdfs:seeAlso "USDA: 44B5.20", "violinID:2313;2314;2315;2316;2317;2318" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001954 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B6.20)" ; rdfs:seeAlso "USDA: 44B6.20", "violinID:2319;2320;2321;2322;2323;2324" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001955 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B6.21)" ; rdfs:seeAlso "USDA: 44B6.21", "violinID:2325;2326;2327;2328;2329;2330" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001956 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C5.20)" ; rdfs:seeAlso "USDA: 44C5.20", "violinID:2343;2344;2345;2346" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001957 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C7.20)" ; rdfs:seeAlso "USDA: 44C7.20", "violinID:2347;2348;2349;2350" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001958 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44D5.20)" ; rdfs:seeAlso "USDA: 44D5.20", "violinID:2367;2368;2369;2370" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001959 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D7.20)" ; rdfs:seeAlso "USDA: 44D7.20", "violinID:2375;2376;2377;2378;2379" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002362, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001960 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D7.22)" ; rdfs:seeAlso "USDA: 44D7.22", "violinID:2380;2381;2382;2383;2384" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002362, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001961 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica Bacterin (USDA: 4477.20)" ; rdfs:seeAlso "USDA: 4477.20", "violinID:2405;2406;2407;2408;2409" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002363, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001962 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.20)" ; rdfs:seeAlso "USDA: 4465.20", "violinID:2426;2427;2428;2429" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001963 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.21)" ; rdfs:seeAlso "USDA: 4465.21", "violinID:2430;2431;2432;2433" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001964 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4465.22)" ; rdfs:seeAlso "USDA: 4465.22", "violinID:2434;2435;2436;2437" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001965 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4466.20)" ; rdfs:seeAlso "USDA: 4466.20", "violinID:2438;2439;2440;2441" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001966 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4466.21)" ; rdfs:seeAlso "USDA: 4466.21", "violinID:2442;2443;2444;2445" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001967 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona-Mannheimia Haemolytica Bacterin (USDA: 4475.20)" ; rdfs:seeAlso "USDA: 4475.20", "violinID:2482;2483;2484;2485" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002366, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001968 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1187.20)" ; rdfs:seeAlso "USDA: 1187.20", "violinID:1303;1304;1305;1306" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001969 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1187.21)" ; rdfs:seeAlso "USDA: 1187.21", "violinID:1307;1308;1309;1310" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001970 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1187.22)" ; rdfs:seeAlso "USDA: 1187.22", "violinID:1311;1312;1313;1314" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001971 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1187.25)" ; rdfs:seeAlso "USDA: 1187.25", "violinID:1315;1316;1317;1318" ; rdfs:subClassOf obo:VO_0002358, [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001972 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1189.00)" ; rdfs:seeAlso "USDA: 1189.00", "violinID:1319;1320;1321;1322" ; rdfs:subClassOf obo:VO_0002358, [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001973 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1189.21)" ; rdfs:seeAlso "USDA: 1189.21", "violinID:1323;1324;1325;1326" ; rdfs:subClassOf obo:VO_0002358, [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001974 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine (USDA: 1189.30)" ; rdfs:seeAlso "USDA: 1189.30", "violinID:1327;1328;1329;1330" ; rdfs:subClassOf obo:VO_0002358, [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001975 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B9.21)" ; rdfs:seeAlso "USDA: 44B9.21", "violinID:2331;2332;2333;2334;2335" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001976 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B9.22)" ; rdfs:seeAlso "USDA: 44B9.22", "violinID:2337;2338;2339;2340;2341;2342" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001977 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44F9.20)" ; rdfs:seeAlso "USDA: 44F9.20", "violinID:2371;2372;2373;2374" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001978 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.20)" ; rdfs:seeAlso "USDA: 4469.20", "violinID:2454;2455;2456;2457" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001979 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.22)" ; rdfs:seeAlso "USDA: 4469.22", "violinID:2458;2459;2460;2461" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001980 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.25)" ; rdfs:seeAlso "USDA: 4469.25", "violinID:2470;2471;2472;2473" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001981 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.30)" ; rdfs:seeAlso "USDA: 4469.30", "violinID:2478;2479;2480;2481" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001982 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.20)" ; rdfs:seeAlso "USDA: 44B1.20", "violinID:2289;2290;2291;2292;2293;2294" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001983 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.22)" ; rdfs:seeAlso "USDA: 44B1.22", "violinID:2295;2296;2297;2298;2299;2300" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001984 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.23)" ; rdfs:seeAlso "USDA: 44B1.23", "violinID:2301;2302;2303;2304;2305;2306" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001985 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44B1.25)" ; rdfs:seeAlso "USDA: 44B1.25", "violinID:2307;2308;2309;2310;2311;2312" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002360, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001986 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.20)" ; rdfs:seeAlso "USDA: 44C9.20", "violinID:2351;2352;2353;2354" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001987 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.21)" ; rdfs:seeAlso "USDA: 44C9.21", "violinID:2355;2356;2357;2358" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001988 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.23)" ; rdfs:seeAlso "USDA: 44C9.23", "violinID:2359;2360;2361;2362" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001989 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus Bacterin (USDA: 44C9.24)" ; rdfs:seeAlso "USDA: 44C9.24", "violinID:2363;2364;2365;2366" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001990 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.20)" ; rdfs:seeAlso "USDA: 44D9.20", "violinID:2385;2386;2387;2388;2389" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002362, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001991 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.21)" ; rdfs:seeAlso "USDA: 44D9.21", "violinID:2390;2391;2392;2393;2394" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002362, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001992 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.23)" ; rdfs:seeAlso "USDA: 44D9.23", "violinID:2395;2396;2397;2398;2399" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002362, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001993 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Haemophilus somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 44D9.24)" ; rdfs:seeAlso "USDA: 44D9.24", "violinID:2400;2401;2402;2403;2404" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002362, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001994 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.20)" ; rdfs:seeAlso "USDA: 4461.20", "violinID:2410;2411;2412;2413" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001995 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.21)" ; rdfs:seeAlso "USDA: 4461.21", "violinID:2414;2415;2416;2417" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001996 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.22)" ; rdfs:seeAlso "USDA: 4461.22", "violinID:2418;2419;2420;2421" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0001997 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4461.25)" ; rdfs:seeAlso "USDA: 4461.25", "violinID:2422;2423;2424;2425" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001998 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.00)" ; rdfs:seeAlso "USDA: 4469.00", "violinID:2446;2447;2448;2449" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0001999 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.01)" ; rdfs:seeAlso "USDA: 4469.01", "violinID:2450;2451;2452;2453" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002000 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.23)" ; rdfs:seeAlso "USDA: 4469.23", "violinID:2462;2463;2464;2465" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002001 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.24)" ; rdfs:seeAlso "USDA: 4469.24", "violinID:2466;2467;2468;2469" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002002 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4469.26)" ; rdfs:seeAlso "USDA: 4469.26", "violinID:2474;2475;2476;2477" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002364, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002003 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Hardjo Bacterin (USDA: 4L49.20)" ; rdfs:seeAlso "USDA: 4L49.20", "violinID:2272;2273;2274;2275;2276" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002368, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002004 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica Toxoid (USDA: 4X49.20)" ; rdfs:seeAlso "USDA: 4X49.20", "violinID:2490;2491;2492;2493" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002369, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002005 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica Toxoid (USDA: 4X49.21)" ; rdfs:seeAlso "USDA: 4X49.21", "violinID:2494;2495;2496;2497" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002369, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002006 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45B9.20)" ; rdfs:seeAlso "USDA: 45B9.20", "violinID:2498;2499;2500;2501;2502" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002370, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002007 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Modified Live Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 45B9.21)" ; rdfs:seeAlso "USDA: 45B9.21", "violinID:2503;2504;2505;2506;2507" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002370, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002008 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus-Mannheimia Haemolytica-Pasteurella Multocida Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 11A8.22)" ; rdfs:seeAlso "USDA: 11A8.22", "violinID:1331;1332;1333;1334;1335;1336" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002009 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 11A5.20)" ; rdfs:seeAlso "USDA: 11A5.20", "violinID:1346;1347;1348" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002372, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002010 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.20)" ; rdfs:seeAlso "USDA: 11A1.20", "violinID:1337;1338;139" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002372, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002011 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.26)" ; rdfs:seeAlso "USDA: 11A1.26", "violinID:1340;1341;1342" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002372, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002012 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine (USDA: 11A1.30)" ; rdfs:seeAlso "USDA: 11A1.30", "violinID:1343;1344;1345" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002372, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002013 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.20)" ; rdfs:seeAlso "USDA: 4367.20", "violinID:2508;2509;2510;2511" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002373, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002014 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.26)" ; rdfs:seeAlso "USDA: 4367.26", "violinID:2512;2513;2514;2515" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002373, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002015 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4367.30)" ; rdfs:seeAlso "USDA: 4367.30", "violinID:2516;2517;2518;2519" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002373, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000057 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002016 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Modified Killed Virus Vaccine (USDA: 1935.20)" ; rdfs:seeAlso "USDA: 1935.20", "violinID:1350" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002374, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002017 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Modified Live Virus Vaccine (USDA: 1931.20)" ; rdfs:seeAlso "USDA: 1931.20", "violinID:1349" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002374, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002018 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 4570.20)" ; rdfs:seeAlso "USDA: 4570.20", "violinID:2520;2521;2522;2523" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002375, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002019 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 4570.22)" ; rdfs:seeAlso "USDA: 4570.22", "violinID:2524;2525;2526;2527" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002375, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002020 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Clostridium Perfringens Types C & D-Escherichia Coli Bacterin-Toxoid (USDA: 4575.20)" ; rdfs:seeAlso "USDA: 4575.20", "violinID:2528;2529;2530;2531" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002376, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002021 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Escherichia Coli Bacterin (USDA: 4585.20)" ; rdfs:seeAlso "USDA: 4585.20", "violinID:2532;2533;2534" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002377, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002022 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Killed Virus Vaccine-Escherichia Coli Bacterin (USDA: 4585.22)" ; rdfs:seeAlso "USDA: 4585.22", "violinID:2535;2536;2537" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002377, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002023 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 45B5.21)" ; rdfs:seeAlso "USDA: 45B5.21", "violinID:2538;2539;2540" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002378, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002024 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine-Haemophilus somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid (USDA: 4C95.20)" ; rdfs:seeAlso "USDA: 4C95.20", "violinID:2541;2542;2543;2544" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002379, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000058 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002025 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4595.21)" ; rdfs:seeAlso "USDA: 4595.21", "violinID:2545;2546" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002380, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002026 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4595.25)" ; rdfs:seeAlso "USDA: 4595.25", "violinID:2547;2548" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002380, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002027 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4599.00)" ; rdfs:seeAlso "USDA: 4599.00", "violinID:2549;2550" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002381, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002028 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea-Respiratory Syncytial Virus Killed Virus Vaccine (USDA: 12A5.20)" ; rdfs:seeAlso "USDA: 12A5.20", "violinID:1360" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002486, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002029 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mannheimia Haemolytica-Pasteurella Multocida Avirulent Live Culture Vaccine (USDA: 1861.01)" ; rdfs:seeAlso "USDA: 1861.01", "violinID:1932;1933" ; rdfs:subClassOf obo:VO_0001217, obo:VO_0001485, obo:VO_0002446, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002030 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis-Fowl Pox-Mycoplasma Gallisepticum Live Fowl Pox Vector, Live Virus Vaccine (USDA:1D61.R0)" ; rdfs:seeAlso "USDA:1D61.R0", "violinID:1143;1145;1144" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002328, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002031 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: )" ; rdfs:seeAlso "USDA:", "violinID:1437;1438" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002032 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Influenza-Fowl Pox H5 Subtype, Live Fowl Pox Vector Vaccine (USDA: 1061.R0)" ; rdfs:seeAlso "USDA: 1061.R0", "violinID:1161;1160" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002329, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002033 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.10 )" ; rdfs:seeAlso "USDA: 10M1.10", "violinID:1131;1130" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002326, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002034 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.11)" ; rdfs:seeAlso "USDA: 10M1.11", "violinID:1133;1132" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002326, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002035 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.13)" ; rdfs:seeAlso "USDA: 10M1.13", "violinID:1135;1134" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002326, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002036 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.14)" ; rdfs:seeAlso "USDA: 10M1.14", "violinID:1137;1136" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002326, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002037 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.40)" ; rdfs:seeAlso "USDA: 10M1.40", "violinID:1139;1138" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002326, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002038 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis-Fowl Pox-Laryngotracheitis Live Virus, Live Fowl Pox Vector Vaccine (USDA: 10S1.R0)" ; rdfs:seeAlso "USDA: 10S1.R0", "violinID:1141;1140;1142" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002327, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002039 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian Encephalomyelitis-Chicken Anemia Virus-Fowl Pox C155Live and Modified Live C212Virus Vaccine (USDA: 10T1.40)+C433" ; rdfs:seeAlso "USDA: 10T1.40", "violinID:1129;1128" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002325, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002040 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotypes 1 & 2 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 1281.R0)" ; rdfs:seeAlso "USDA: 1281.R0", "violinID:1415;1416" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002041 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotypes 1 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 1281.R1)" ; rdfs:seeAlso "USDA: 1281.R1", "violinID:1417;1418" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002042 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Variant, Serotype 3, Live Virus Vaccine (USDA: 1282.50)" ; rdfs:seeAlso "USDA: 1282.50", "violinID:1419;1420" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002043 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1288.42)" ; rdfs:seeAlso "USDA: 1288.42", "violinID:1421;1422" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002044 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1288.43)" ; rdfs:seeAlso "USDA: 1288.43", "violinID:1423;1424" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002045 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1288.44)" ; rdfs:seeAlso "USDA: 1288.44", "violinID:1425;1426" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002046 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1288.45)" ; rdfs:seeAlso "USDA: 1288.45", "violinID:1427;1428" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002047 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1288.4A)" ; rdfs:seeAlso "USDA: 1288.4A", "violinID:1429;1430" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002048 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C2.50)" ; rdfs:seeAlso "USDA: 12C2.50", "violinID:1431;1432" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002049 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C2.51)" ; rdfs:seeAlso "USDA: 12C2.51", "violinID:1433;1434" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002050 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Variant Strain, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C2.52)" ; rdfs:seeAlso "USDA: 12C2.52", "violinID:1435;1436" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002051 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Standard & Variant, Serotype 3, Live Virus Vaccine (USDA: 12C8.40)" ; rdfs:seeAlso "USDA: 12C8.40", "violinID:1439;1440" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002052 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Standard & Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C8.42)" ; rdfs:seeAlso "USDA: 12C8.42", "violinID:1441;1442" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002053 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Standard & Variant, Serotype 3, Live Virus Vaccine (USDA: 12C8.43)" ; rdfs:seeAlso "USDA: 12C8.43", "violinID:1443;1444" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002054 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Standard & Variant, Serotypes 2 & 3, Live Virus Vaccine (USDA: 12C8.44)" ; rdfs:seeAlso "USDA: 12C8.44", "violinID:1445;1446" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002055 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.01)" ; rdfs:seeAlso "USDA: 12D5.01", "violinID:1539;1540" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002056 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Killed Virus Vaccine (USDA: 12D5.02)" ; rdfs:seeAlso "USDA: 12D5.02", "violinID:1541;1542" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002057 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.03)" ; rdfs:seeAlso "USDA: 12D5.03", "violinID:1543;1544" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002058 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.04)" ; rdfs:seeAlso "USDA: 12D5.04", "violinID:1545;1546" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002059 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.30)" ; rdfs:seeAlso "USDA: 12D5.30", "violinID:1547;1548" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002060 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Standard & Variant, Mass & Ark Types, Killed Virus Vaccine (USDA: 12D5.45)" ; rdfs:seeAlso "USDA: 12D5.45", "violinID:1467;1465;1466" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002061 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.E0)" ; rdfs:seeAlso "USDA: 12D5.E0", "violinID:1549;1550" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002062 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.F0)" ; rdfs:seeAlso "USDA: 12D5.F0", "violinID:1551;1552" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002063 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.F1)" ; rdfs:seeAlso "USDA: 12D5.F1", "violinID:1553;1554" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002064 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12D5.T0)" ; rdfs:seeAlso "USDA: 12D5.T0", "violinID:1555;1556" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002385, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002065 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.10)" ; rdfs:seeAlso "USDA: 12G5.10", "violinID:1457;1458" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002365, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002066 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.11)" ; rdfs:seeAlso "USDA: 12G5.11", "violinID:1459;1460" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002365, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002067 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease Standard & Variant, Killed Virus Vaccine (USDA: 12G5.42)" ; rdfs:seeAlso "USDA: 12G5.42", "violinID:1461;1462" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002365, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002068 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease Killed Virus Vaccine (USDA: 12G5.43)" ; rdfs:seeAlso "USDA: 12G5.43", "violinID:1463;1464" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002365, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002069 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 12H1.4M)" ; rdfs:seeAlso "USDA: 12H1.4M", "violinID:1469;1468;1470" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002070 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 12H1.67)" ; rdfs:seeAlso "USDA: 12H1.67", "violinID:1471;1473;1472" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002071 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.40)" ; rdfs:seeAlso "USDA: 12J5.40", "violinID:1475;1474;1476" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002072 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.43)" ; rdfs:seeAlso "USDA: 12J5.43", "violinID:1477;1479;1478" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002073 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Standard & Variant, Mass Type, Killed Virus Vaccine (USDA: 12J5.61)" ; rdfs:seeAlso "USDA: 12J5.61", "violinID:1481;1480;1482" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002074 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 12J5.62)" ; rdfs:seeAlso "USDA: 12J5.62", "violinID:1483;1485;1484" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002075 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.00)" ; rdfs:seeAlso "USDA: 12M5.00", "violinID:1487;1489;1486;1488" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002076 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.01)" ; rdfs:seeAlso "USDA: 12M5.01", "violinID:1491;1493;1490;1492" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002077 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.11)" ; rdfs:seeAlso "USDA: 12M5.11", "violinID:1495;1497;1494;1496" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002078 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Killed Virus Vaccine (USDA: 12M5.40)" ; rdfs:seeAlso "USDA: 12M5.40", "violinID:1499;1501;1500;1498" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002079 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass & Ark Types, Killed Virus Vaccine (USDA: 12M5.41)" ; rdfs:seeAlso "USDA: 12M5.41", "violinID:1503;1505;1502;1504" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002080 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass & Ark Types, Killed Virus Vaccine (USDA: 12M5.42)" ; rdfs:seeAlso "USDA: 12M5.42", "violinID:1507;1509;1506;1508" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002081 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.43)" ; rdfs:seeAlso "USDA: 12M5.43", "violinID:1511;1513;1510;1512" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002082 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.50)" ; rdfs:seeAlso "USDA: 12M5.50", "violinID:1517;1515;1516;1514" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002083 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.90)" ; rdfs:seeAlso "USDA: 12M5.90", "violinID:1519;1521;1518;1520" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002084 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Mass Type, Killed Virus Vaccine (USDA: 12M5.91)" ; rdfs:seeAlso "USDA: 12M5.91", "violinID:1523;1525;1522;1524" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002085 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Standard & Variant, Mass Type, Killed Virus Vaccine (USDA: 12M5.E0)" ; rdfs:seeAlso "USDA: 12M5.E0", "violinID:1527;1529;1526;1528" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002383, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002086 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12P5.40)" ; rdfs:seeAlso "USDA: 12P5.40", "violinID:1531;1532;1530" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002384, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002087 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12P5.41)" ; rdfs:seeAlso "USDA: 12P5.41", "violinID:1533;1535;1534" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002384, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002088 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Reovirus Standard & Variant, Killed Virus Vaccine (USDA: 12P5.E0)" ; rdfs:seeAlso "USDA: 12P5.E0", "violinID:1537;1536;1538" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002384, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002089 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Modified Live Virus & Avirulent Live Culture Vaccine (USDA: 12X1.20)" ; rdfs:seeAlso "USDA: 12X1.20", "violinID:1559;1558;1560" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002386, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002090 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.20)" ; rdfs:seeAlso "USDA: 1331.20", "violinID:1657;1659;1658" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002413, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002091 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.25)" ; rdfs:seeAlso "USDA: 1331.25", "violinID:1661;1660;1662" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002413, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002092 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.27)" ; rdfs:seeAlso "USDA: 1331.27", "violinID:1665;1663;1664" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002413, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002093 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus Vaccine (USDA: 1331.30)" ; rdfs:seeAlso "USDA: 1331.30", "violinID:1667;1666;1668" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002413, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002094 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Modified Live Virus, Canarypox Vector Vaccine (USDA: 1331.R1)" ; rdfs:seeAlso "USDA: 1331.R1", "violinID:1669;1671;1670" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002413, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002095 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Measles-Parainfluenza Modified Live Virus Vaccine (USDA: 1341.20)" ; rdfs:seeAlso "USDA: 1341.20", "violinID:1605;1607;1606;1608" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002406, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002096 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Measles Modified Live Virus Vaccine (USDA: 1351.20)" ; rdfs:seeAlso "USDA: 1351.20", "violinID:1685;1686" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002416, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002097 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Hepatitis-Parainfluenza Modified Live Virus Vaccine (USDA: 1381.21)" ; rdfs:seeAlso "USDA: 1381.21", "violinID:1683;1682;1684" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002415, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002098 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine (USDA: 13A1.20)" ; rdfs:seeAlso "USDA: 13A1.20", "violinID:1577;1576" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002394, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002099 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine (USDA: 13A1.27)" ; rdfs:seeAlso "USDA: 13A1.27", "violinID:1579;1578" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002394, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002100 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza Modified Live Virus Vaccine (USDA: 13C1.20)" ; rdfs:seeAlso "USDA: 13C1.20", "violinID:1609;1611;1610" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002407, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002101 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.20)" ; rdfs:seeAlso "USDA: 13D1.20", "violinID:1615;1613;1612;1614" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002102 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.21)" ; rdfs:seeAlso "USDA: 13D1.21", "violinID:1617;1619;1616;1618" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002103 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.22)" ; rdfs:seeAlso "USDA: 13D1.22", "violinID:1621;1623;1620;1622" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002104 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.23)" ; rdfs:seeAlso "USDA: 13D1.23", "violinID:1625;1627;1624;1626" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002105 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.25)" ; rdfs:seeAlso "USDA: 13D1.25", "violinID:1631;1629;1628;1630" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002106 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.27)" ; rdfs:seeAlso "USDA: 13D1.27", "violinID:1633;1635;1632;1634" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002107 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.28)" ; rdfs:seeAlso "USDA: 13D1.28", "violinID:1637;1639;1636;1638" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002108 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.29)" ; rdfs:seeAlso "USDA: 13D1.29", "violinID:1641;1643;1640;1642" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002109 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Canarypox Vector Vaccine (USDA: 13D1.R1)" ; rdfs:seeAlso "USDA: 13D1.R1", "violinID:1645;1647;1644;1646" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002110 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine (USDA: 13D1.T0)" ; rdfs:seeAlso "USDA: 13D1.T0", "violinID:1649;1651;1648;1650" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002111 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus-Rabies Modified Live & Killed Virus Vaccine (USDA: 13G9.20)" ; rdfs:seeAlso "USDA: 13G9.20", "violinID:1653;1655;1652;1654;1656" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002466, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002112 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus-Rabies Modified Live & Killed Virus Vaccine (USDA: 13H9.20)" ; rdfs:seeAlso "USDA: 13H9.20", "violinID:1673;1675;1672;1674" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002414, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002113 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.20)" ; rdfs:seeAlso "USDA: 13P1.20", "violinID:1687;1688" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002417, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002114 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Parvovirus Modified Live Virus Vaccine (USDA: 13P1.27)" ; rdfs:seeAlso "USDA: 13P1.27", "violinID:1689;1690" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002417, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002115 obo:IAO_0000115 "A horse Encephalomyelitis-Influenza-West Nile Virus vaccine that is inactivated and manufactured by Wyeth Pharmaceuticals Inc. " ; obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza-West Nile Virus Eastern & Western, Killed Virus Vaccine (USDA: 13W5.20)" ; rdfs:seeAlso "USDA: 13W5.20", "violinID:1717;1719;1718;1720" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002483, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002116 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine (USDA: 1475.00)" ; rdfs:seeAlso "USDA: 1475.00", "violinID:1715;1716" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002424, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002117 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14D7.20)" ; rdfs:seeAlso "USDA: 14D7.20", "violinID:1677;1676;1678" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002482, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002118 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14D9.27)" ; rdfs:seeAlso "USDA: 14D9.27", "violinID:1681;1679;1680" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002482, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002119 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Parainfluenza-Bordetella Bronchiseptica Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 14M1.20)" ; rdfs:seeAlso "USDA: 14M1.20", "violinID:1693;1694" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002418, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002120 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Parainfluenza-Bordetella Bronchiseptica Modified Live Virus, Avirulent Live Culture Vaccine (USDA: 14M1.22)" ; rdfs:seeAlso "USDA: 14M1.22", "violinID:1695;1696" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002418, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002121 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus-Parvovirus Modified Live Virus Vaccine (USDA: 14R1.20)" ; rdfs:seeAlso "USDA: 14R1.20", "violinID:1565;1564" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002393, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002122 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.20)" ; rdfs:seeAlso "USDA: 14R7.20", "violinID:1567;1566" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002393, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002123 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.21)" ; rdfs:seeAlso "USDA: 14R7.21", "violinID:1569;1568" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002393, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002124 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.22)" ; rdfs:seeAlso "USDA: 14R7.22", "violinID:1571;1570" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002393, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002125 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.25)" ; rdfs:seeAlso "USDA: 14R7.25", "violinID:1573;1572" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002393, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002126 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 14R7.29)" ; rdfs:seeAlso "USDA: 14R7.29", "violinID:1575;1574" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002393, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002127 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus Vaccine (USDA: 14W5.22)" ; rdfs:seeAlso "USDA: 14W5.22", "violinID:1721;1723;1722" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002401, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002128 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western & Venezuelan, Killed Virus Vaccine (USDA: 14W5.23)" ; rdfs:seeAlso "USDA: 14W5.23", "violinID:1725;1727;1724;1726" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002431, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002129 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus, Live Canarypox Vector Vaccine (USDA: 14W7.R0)" ; rdfs:seeAlso "USDA: 14W7.R0", "violinID:1729;1728;1730" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002401, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002130 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.24)" ; rdfs:seeAlso "USDA: 1515.24", "violinID:1747;1746" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002421, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002131 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.26)" ; rdfs:seeAlso "USDA: 1515.26", "violinID:1749;1748" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002421, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002132 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.27)" ; rdfs:seeAlso "USDA: 1515.27", "violinID:1751;1750" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002421, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002133 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis-Influenza Killed Virus Vaccine (USDA: 1515.2A)" ; rdfs:seeAlso "USDA: 1515.2A", "violinID:1753;1752" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002421, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002134 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Equine Rhinopneumonitis-Influenza Modified Live & Killed Virus Vaccine (USDA: 1518.20)" ; rdfs:seeAlso "USDA: 1518.20", "violinID:1755;1754" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002421, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002135 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live Virus; Canarypox Vector Vaccine (USDA: 1591.R1)" ; rdfs:seeAlso "USDA: 1591.R1", "violinID:1583;1581;1582;1584;1580" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002395, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002136 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.20)" ; rdfs:seeAlso "USDA: 1599.20", "violinID:1585;1587;1589;1586;1588" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002395, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002137 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.21)" ; rdfs:seeAlso "USDA: 1599.21", "violinID:1591;1593;1590;1592;1594" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002395, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002138 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.25)" ; rdfs:seeAlso "USDA: 1599.25", "violinID:1599;1595;1597;1598;1596" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002395, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002139 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine (USDA: 1599.29)" ; rdfs:seeAlso "USDA: 1599.29", "violinID:1601;1603;1600;1602;1604" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001485, obo:VO_0002395, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002140 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox-Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 15E2.00)" ; rdfs:seeAlso "USDA: 15E2.00", "violinID:1922;1921" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002444, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002141 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis-Marek's Disease Serotype 3, Live Marek's Disease Vector Vaccine (USDA: 16J1.R1)" ; rdfs:seeAlso "USDA: 16J1.R1", "violinID:1910;1909" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002441, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002142 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis-Marek's Disease Serotypes 2 & 3, Modified Live & Live Marek's Disease Vector Vaccine (USDA: 16J1.R2)" ; rdfs:seeAlso "USDA: 16J1.R2", "violinID:1912;1911" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002441, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002143 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease-Newcastle Disease Serotype 3, Live Marek's Disease Vector Vaccine (USDA: 16N1.R0)" ; rdfs:seeAlso "USDA: 16N1.R0", "violinID:1954;1953" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, obo:VO_0002447, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002144 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease-Newcastle Disease Serotypes 1 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 16N1.R1)" ; rdfs:seeAlso "USDA: 16N1.R1", "violinID:1956;1955" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, obo:VO_0002447, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002145 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease-Newcastle Disease Serotypes 1 & 2 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 16N1.R2)" ; rdfs:seeAlso "USDA: 16N1.R2", "violinID:1958;1957" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, obo:VO_0002447, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002146 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease-Tenosynovitis Serotypes 2 & 3, Live & Modified Live Virus Vaccine (USDA: 16T1.00)" ; rdfs:seeAlso "USDA: 16T1.00", "violinID:1964;1963" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002448, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002147 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease-Tenosynovitis Serotypes 2 & 3, Live Virus Vaccine (USDA: 16T1.03)" ; rdfs:seeAlso "USDA: 16T1.03", "violinID:1966;1965" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002448, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002148 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.11)" ; rdfs:seeAlso "USDA: 1761.11", "violinID:1996;1997" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002149 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.12)" ; rdfs:seeAlso "USDA: 1761.12", "violinID:1998;1999" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002150 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1761.13)" ; rdfs:seeAlso "USDA: 1761.13", "violinID:2000;2001" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002151 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1761.14)" ; rdfs:seeAlso "USDA: 1761.14", "violinID:2002;2003" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002152 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1761.15)" ; rdfs:seeAlso "USDA: 1761.15", "violinID:2004;2005" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002153 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1761.17)" ; rdfs:seeAlso "USDA: 1761.17", "violinID:2006;2007" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002154 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.18)" ; rdfs:seeAlso "USDA: 1761.18", "violinID:2008;2009" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002155 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1761.19)" ; rdfs:seeAlso "USDA: 1761.19", "violinID:2010;2011" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002156 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1761.1A)" ; rdfs:seeAlso "USDA: 1761.1A", "violinID:2012;2013" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002157 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1762.11)" ; rdfs:seeAlso "USDA: 1762.11", "violinID:2014;2015" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002158 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Conn Type, Live Virus Vaccine (USDA: 1762.13)" ; rdfs:seeAlso "USDA: 1762.13", "violinID:2016;2017" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002159 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1762.1H)" ; rdfs:seeAlso "USDA: 1762.1H", "violinID:2018;2019" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002160 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.11)" ; rdfs:seeAlso "USDA: 1771.11", "violinID:2020;2021" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002161 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.12)" ; rdfs:seeAlso "USDA: 1771.12", "violinID:2022;2023" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002162 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1771.14)" ; rdfs:seeAlso "USDA: 1771.14", "violinID:2024;2025" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002163 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1771.17)" ; rdfs:seeAlso "USDA: 1771.17", "violinID:2026;2027" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002164 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.18)" ; rdfs:seeAlso "USDA: 1771.18", "violinID:2028;2029" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002165 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.19)" ; rdfs:seeAlso "USDA: 1771.19", "violinID:2030;2031" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002166 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass Type, Live Virus Vaccine (USDA: 1771.1A)" ; rdfs:seeAlso "USDA: 1771.1A", "violinID:2032;2033" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002167 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1775.10)" ; rdfs:seeAlso "USDA: 1775.10", "violinID:2034;2035" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002168 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1775.11)" ; rdfs:seeAlso "USDA: 1775.11", "violinID:2036;2037" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002169 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1776.10)" ; rdfs:seeAlso "USDA: 1776.10", "violinID:2038;2039" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002170 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass & Ark Types, Killed Virus Vaccine (USDA: 1785.10)" ; rdfs:seeAlso "USDA: 1785.10", "violinID:2040;2041" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002171 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine (USDA: 1785.11)" ; rdfs:seeAlso "USDA: 1785.11", "violinID:2042;2043" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002172 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass & Ark Types, Killed Virus Vaccine (USDA: 1785.12)" ; rdfs:seeAlso "USDA: 1785.12", "violinID:2044;2045" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002173 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1791.14)" ; rdfs:seeAlso "USDA: 1791.14", "violinID:2046;2047" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002174 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1791.15)" ; rdfs:seeAlso "USDA: 1791.15", "violinID:2048;2049" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002175 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass Type, Live Virus Vaccine (USDA: 1791.19)" ; rdfs:seeAlso "USDA: 1791.19", "violinID:2050;2051" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002176 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 1791.1X)" ; rdfs:seeAlso "USDA: 1791.1X", "violinID:2054;2055;2052;2053" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002177 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 17A1.1M)" ; rdfs:seeAlso "USDA: 17A1.1M", "violinID:2056;2057" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002178 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 17A1.1N)" ; rdfs:seeAlso "USDA: 17A1.1N", "violinID:2058;2059" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002179 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, B1 Strain, Mass & Ark Types, Live Virus Vaccine (USDA: 17A2.1M)" ; rdfs:seeAlso "USDA: 17A2.1M", "violinID:2060;2061" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002180 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, LaSota Strain, Mass & Conn Types Vaccine (USDA: 17B1.17)" ; rdfs:seeAlso "USDA: 17B1.17", "violinID:2062;2063" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002181 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease-Fowl Pox Live Fowl Pox Vector Vaccine (USDA: 17C1.R0)" ; rdfs:seeAlso "USDA: 17C1.R0", "violinID:1994;1995" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002456, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002182 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease-Newcastle Disease Serotypes 2 & 3, Live Virus & Live Marek's Disease Vector Vaccine (USDA: 17H1.R1)" ; rdfs:seeAlso "USDA: 17H1.R1", "violinID:1960;1959" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, obo:VO_0002447, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002183 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease-Newcastle Disease Serotypes 2 & 3, Live Virus & Live Marek's Disease Vector Vaccine (USDA: 17H1.R2)" ; rdfs:seeAlso "USDA: 17H1.R2", "violinID:1962;1961" ; rdfs:subClassOf obo:VO_0001018, obo:VO_0001485, obo:VO_0002447, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002184 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Paramyxovirus Type 3, Killed Virus Vaccine (USDA: 17P5.10)" ; rdfs:seeAlso "USDA: 17P5.10", "violinID:2072;2073" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0002458, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002185 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis VG/GA Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 17V1.10)" ; rdfs:seeAlso "USDA: 17V1.10", "violinID:2064;2065" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002186 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis VG/GA Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 17V1.11)" ; rdfs:seeAlso "USDA: 17V1.11", "violinID:2066;2067" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002187 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0001826 ; a owl:Class ; rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.12)" ; rdfs:seeAlso "USDA: 19A5.12", "violinID:2128" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002188 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0001827 ; a owl:Class ; rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.22)" ; rdfs:seeAlso "USDA: 19A5.22", "violinID:2129" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002189 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0001828 ; a owl:Class ; rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.23)" ; rdfs:seeAlso "USDA: 19A5.23", "violinID:2130" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002190 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0001829 ; a owl:Class ; rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.24)" ; rdfs:seeAlso "USDA: 19A5.24", "violinID:2131" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002191 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0001830 ; a owl:Class ; rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.26)" ; rdfs:seeAlso "USDA: 19A5.26", "violinID:2132" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002192 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0001831 ; a owl:Class ; rdfs:label "obsolete Swine Influenza H1N1 & H3N2, Killed Virus Vaccine (USDA: 19A5.29)" ; rdfs:seeAlso "USDA: 19A5.29", "violinID:2133" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002193 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine (USDA: 19H1.20)" ; rdfs:seeAlso "USDA: 19H1.20", "violinID:2106;2105" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002475, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002194 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0001825 ; a owl:Class ; rdfs:label "obsolete Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine (USDA: 19K5.R0)" ; rdfs:seeAlso "USDA: 19K5.R0", "violinID:2096" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002195 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Circovirus Type 1 - Type 2 Chimera, Killed Virus Vaccine (USDA: 19K5.R1)" ; rdfs:seeAlso "USDA: 19K5.R1", "violinID:2097" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001485, obo:VO_0001524, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002196 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotype 3, Live Virus Vaccine (USDA: 1A82.50)" ; rdfs:seeAlso "USDA: 1A82.50", "violinID:1447;1448" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002197 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotype 3, Live Marek's Disease Vector Vaccine (USDA: 1A88.R0)" ; rdfs:seeAlso "USDA: 1A88.R0", "violinID:1449;1450" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002198 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 1A88.R1)" ; rdfs:seeAlso "USDA: 1A88.R1", "violinID:1451;1452" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002199 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus, Live Marek's Disease Vector Vaccine (USDA: 1A88.R2)" ; rdfs:seeAlso "USDA: 1A88.R2", "violinID:1453;1454" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002200 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Marek's Disease Serotypes 2 & 3, Live Virus Vaccine (USDA: 1B82.50)" ; rdfs:seeAlso "USDA: 1B82.50", "violinID:1455;1456" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002382, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002201 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox-Mycoplasma Gallisepticum Live Fowl Pox Vector Vaccine (USDA: 1D51.R0)" ; rdfs:seeAlso "USDA: 1D51.R0", "violinID:1924;1923" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002445, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002202 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox-Laryngotracheitis Live Fowl Pox Vector Vaccine (USDA: 1F31.R0)" ; rdfs:seeAlso "USDA: 1F31.R0", "violinID:1920;1919" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002443, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002203 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, C2 Strain, Mass Type, Live Virus Vaccine (USDA: 1XB1.10)" ; rdfs:seeAlso "USDA: 1XB1.10", "violinID:2068;2069" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002204 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis B1 Type, C2 Strain, Mass & Conn Types, Live Virus Vaccine (USDA: 1XC1.10)" ; rdfs:seeAlso "USDA: 1XC1.10", "violinID:2070;2071" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002205 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Respiratory Syncytial Virus Killed Virus Vaccine-Haemophilus somnus Bacterin (USDA: 40A5.20)" ; rdfs:seeAlso "USDA: 40A5.20", "violinID:2150;2151" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002489, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002206 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4629.20)" ; rdfs:seeAlso "USDA: 4629.20", "violinID:2574;2576;2575" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002397, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002207 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2 Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4629.27)" ; rdfs:seeAlso "USDA: 4629.27", "violinID:2572;2573;2571" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002396, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002208 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.20)" ; rdfs:seeAlso "USDA: 4637.20", "violinID:2698;2697;2696;2700;2699" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002412, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002209 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.22)" ; rdfs:seeAlso "USDA: 4637.22", "violinID:2704;2702;2705;2701;2703" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002412, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002210 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4637.23)" ; rdfs:seeAlso "USDA: 4637.23", "violinID:2706;2708;2710;2707;2709" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002412, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002211 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4637.29)" ; rdfs:seeAlso "USDA: 4637.29", "violinID:2672;2674;2671;2673;2675" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002409, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002212 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.21)" ; rdfs:seeAlso "USDA: 4639.21", "violinID:2712;2714;2711;2713;2715" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002412, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002213 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.22)" ; rdfs:seeAlso "USDA: 4639.22", "violinID:2716;2718;2720;2717;2719" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002412, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002214 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 4639.25)" ; rdfs:seeAlso "USDA: 4639.25", "violinID:2676;2678;2680;2677;2679" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002409, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002215 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.27)" ; rdfs:seeAlso "USDA: 4639.27", "violinID:2688;2690;2686;2689;2687" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002411, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002216 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 4639.28)" ; rdfs:seeAlso "USDA: 4639.28", "violinID:2692;2694;2691;2693;2695" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002411, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002217 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4639.R1)" ; rdfs:seeAlso "USDA: 4639.R1", "violinID:2722;2724;2721;2723;2725" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002404, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002218 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4659.20)" ; rdfs:seeAlso "USDA: 4659.20", "violinID:2668;2670;2667;2669" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002425, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002219 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46B9.21)" ; rdfs:seeAlso "USDA: 46B9.21", "violinID:2590;2592;2594;2589;2591;2593;2595" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002399, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002220 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46D5.27)" ; rdfs:seeAlso "USDA: 46D5.27", "violinID:1154;1159" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002391, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002221 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46E5.20)" ; rdfs:seeAlso "USDA: 46E5.20", "violinID:1153;1158" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002390, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002222 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46E5.21)" ; rdfs:seeAlso "USDA: 46E5.21", "violinID:1145;1144" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002389, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002223 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46E5.23)" ; rdfs:seeAlso "USDA: 46E5.23", "violinID:1150;1151" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002390, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002224 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46E5.24)" ; rdfs:seeAlso "USDA: 46E5.24", "violinID:1147;1149" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002389, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002225 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46E5.25)" ; rdfs:seeAlso "USDA: 46E5.25", "violinID:1152;1146" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002390, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002226 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.20)" ; rdfs:seeAlso "USDA: 46J7.20", "violinID:2632;2634;2636;2633;2635;2637" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002403, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002227 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J7.22)" ; rdfs:seeAlso "USDA: 46J7.22", "violinID:2640;2642;2638;2639;2641;2643" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002403, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002228 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J8.20)" ; rdfs:seeAlso "USDA: 46J8.20", "violinID:2726;2728;2730;2727;2729" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002412, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002229 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.20)" ; rdfs:seeAlso "USDA: 46J9.20", "violinID:2644;2646;2648;2645;2647;2649" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002403, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002230 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.21)" ; rdfs:seeAlso "USDA: 46J9.21", "violinID:2614;2616;2618;2615;2617;2619" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002487, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002231 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.25)" ; rdfs:seeAlso "USDA: 46J9.25", "violinID:2596;2598;2600;2597;2599;2601" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002400, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002232 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.26)" ; rdfs:seeAlso "USDA: 46J9.26", "violinID:2622;2624;2620;2623;2625;2621" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002487, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002233 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 46J9.27)" ; rdfs:seeAlso "USDA: 46J9.27", "violinID:2626;2628;2630;2627;2629;2631" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002487, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002234 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 46J9.29)" ; rdfs:seeAlso "USDA: 46J9.29", "violinID:2606;2602;2604;2607;2603;2605" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002400, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002235 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live Virus, Live Canarypox Vector Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 46J9.R1)" ; rdfs:seeAlso "USDA: 46J9.R1", "violinID:2650;2652;2654;2655;2651;2653" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002403, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002236 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46L9.27)" ; rdfs:seeAlso "USDA: 46L9.27", "violinID:2656;2658;2660;2657;2659;2661" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002404, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002237 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46P9.27)" ; rdfs:seeAlso "USDA: 46P9.27", "violinID:2662;2664;2666;2663;2665" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002405, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002238 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza-West Nile Virus Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 46W5.21)" ; rdfs:seeAlso "USDA: 46W5.21", "violinID:2800;2799;2801" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002423, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002239 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47A5.20)" ; rdfs:seeAlso "USDA: 47A5.20", "violinID:1137;1136" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002392, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002240 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Parvovirus Modified Live Virus Vaccine-Leptospira Canicola Icterohaemorrhagiae Bacterin (USDA: 47B1.20)" ; rdfs:seeAlso "USDA: 47B1.20", "violinID:2738;2739" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002419, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002241 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47C5.20)" ; rdfs:seeAlso "USDA: 47C5.20", "violinID:2578;2580;2582;2577;2579;2581" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002398, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002242 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Borrelia Burgdorferi Bacterin (USDA: 47C5.29)" ; rdfs:seeAlso "USDA: 47C5.29", "violinID:2584;2586;2588;2583;2585;2587" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002398, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002243 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract (USDA: 47E5.20)" ; rdfs:seeAlso "USDA: 47E5.20", "violinID:1140;1142;1143" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002388, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002244 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Killed Virus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract (USDA: 47E5.21)" ; rdfs:seeAlso "USDA: 47E5.21", "violinID:1139;1138;1141" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002387, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001001 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002245 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47K1.20)" ; rdfs:seeAlso "USDA: 47K1.20", "violinID:2682;2684;2681;2683;2685" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002410, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002246 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin (USDA: 47L9.20)" ; rdfs:seeAlso "USDA: 47L9.20", "violinID:2608;2610;2612;2609;2611;2613" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002402, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002247 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Hepatitis-Parainfluenza-Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 47P9.22)" ; rdfs:seeAlso "USDA: 47P9.22", "violinID:2732;2734;2731;2733;2735" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002426, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002248 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.20)" ; rdfs:seeAlso "USDA: 4835.20", "violinID:2768;2770;2769" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002422, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002249 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.23)" ; rdfs:seeAlso "USDA: 4835.23", "violinID:2772;2771;2773" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002422, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002250 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.24)" ; rdfs:seeAlso "USDA: 4835.24", "violinID:2774;2776;2775" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002422, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002251 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.45)" ; rdfs:seeAlso "USDA: 4835.45", "violinID:2778;2777;2779" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002422, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002252 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4835.46)" ; rdfs:seeAlso "USDA: 4835.46", "violinID:2780;2782;2781" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002422, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002253 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4844.30)" ; rdfs:seeAlso "USDA: 4844.30", "violinID:2804;2802;2805;2803" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002428, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002254 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4845.23)" ; rdfs:seeAlso "USDA: 4845.23", "violinID:2806;2808;2810;2807;2809" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002429, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002255 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4845.24)" ; rdfs:seeAlso "USDA: 4845.24", "violinID:2812;2814;2811;2813;2815" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002429, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002256 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4845.32)" ; rdfs:seeAlso "USDA: 4845.32", "violinID:2820;2816;2818;2817;2819" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002429, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002257 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4845.33)" ; rdfs:seeAlso "USDA: 4845.33", "violinID:2822;2824;2821;2823;2825" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002429, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002258 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4847.22)" ; rdfs:seeAlso "USDA: 4847.22", "violinID:2826;2828;2830;2827;2829;2831" ; rdfs:subClassOf obo:VO_0000542, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002259 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4847.23)" ; rdfs:seeAlso "USDA: 4847.23", "violinID:2832;2834;2836;2837;2833;2835" ; rdfs:subClassOf obo:VO_0000542, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002260 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4847.24)" ; rdfs:seeAlso "USDA: 4847.24", "violinID:2838;2840;2842;2839;2841;2843" ; rdfs:subClassOf obo:VO_0000542, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002261 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4847.32)" ; rdfs:seeAlso "USDA: 4847.32", "violinID:2844;2846;2848;2845;2847;2849" ; rdfs:subClassOf obo:VO_0000542, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002262 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Rhinopneumonitis-Influenza-West Nile Virus Eastern & Western, Killed Virus, Killed Flavivirus Chimera Vaccine-Tetanus Toxoid (USDA: 4855.R2)" ; rdfs:seeAlso "USDA: 4855.R2", "violinID:2854;2850;2852;2853;2855;2851" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002430, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002263 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.00)" ; rdfs:seeAlso "USDA: 4865.00", "violinID:2740;2742;2741" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002420, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002264 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.01)" ; rdfs:seeAlso "USDA: 4865.01", "violinID:2744;2743;2745" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002420, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002265 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.21)" ; rdfs:seeAlso "USDA: 4865.21", "violinID:2746;2748;2747" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002420, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002266 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.23)" ; rdfs:seeAlso "USDA: 4865.23", "violinID:2750;2752;2749;2751" ; rdfs:subClassOf obo:VO_0000541, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002267 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.26)" ; rdfs:seeAlso "USDA: 4865.26", "violinID:2754;2755;2753" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002420, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002268 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4865.27)" ; rdfs:seeAlso "USDA: 4865.27", "violinID:2756;2758;2757;2759" ; rdfs:subClassOf obo:VO_0000541, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002269 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4867.20)" ; rdfs:seeAlso "USDA: 4867.20", "violinID:2760;2762;2761;2763" ; rdfs:subClassOf obo:VO_0000541, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002270 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4867.21)" ; rdfs:seeAlso "USDA: 4867.21", "violinID:2764;2766;2765;2767" ; rdfs:subClassOf obo:VO_0000541, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002271 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4875.23)" ; rdfs:seeAlso "USDA: 4875.23", "violinID:2784;2786;2783;2785" ; rdfs:subClassOf obo:VO_0000539, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002272 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4875.24)" ; rdfs:seeAlso "USDA: 4875.24", "violinID:2788;2790;2787;2789" ; rdfs:subClassOf obo:VO_0000539, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002273 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4875.A0)" ; rdfs:seeAlso "USDA: 4875.A0", "violinID:2792;2794;2791;2793" ; rdfs:subClassOf obo:VO_0000539, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002274 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-Influenza Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 4875.A1)" ; rdfs:seeAlso "USDA: 4875.A1", "violinID:2796;2798;2795;2797" ; rdfs:subClassOf obo:VO_0000539, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002275 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Mycoplasma Gallisepticum Bacterin (USDA: 48B5.10)" ; rdfs:seeAlso "USDA: 48B5.10", "violinID:2912;2911;2913" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002454, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002276 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Mycoplasma Gallisepticum Bacterin (USDA: 48B6.10)" ; rdfs:seeAlso "USDA: 48B6.10", "violinID:2914;2916;2915" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002454, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002277 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.01)" ; rdfs:seeAlso "USDA: 48C5.01", "violinID:2934;2933;2935" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002461, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002278 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.20)" ; rdfs:seeAlso "USDA: 48C5.20", "violinID:2936;2938;2937" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002461, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002279 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.21)" ; rdfs:seeAlso "USDA: 48C5.21", "violinID:2940;2939;2941" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002461, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002280 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 48C5.22)" ; rdfs:seeAlso "USDA: 48C5.22", "violinID:2942;2944;2943" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002461, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002281 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Mass Type, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D6.10)" ; rdfs:seeAlso "USDA: 48D6.10", "violinID:2918;2919;2917" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002453, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002282 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease-Bronchitis Mass & Ark Types, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D7.10)" ; rdfs:seeAlso "USDA: 48D7.10", "violinID:2906;2905;2907" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002453, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002283 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease-Bronchitis Mass & Ark Types, Killed Virus Vaccine-Salmonella Enteritidis Bacterin (USDA: 48D7.11)" ; rdfs:seeAlso "USDA: 48D7.11", "violinID:2908;2910;2909" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002453, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001027 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002284 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.20)" ; rdfs:seeAlso "USDA: 48W5.20", "violinID:2856;2858;2860;2857;2859" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002431, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002285 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.21)" ; rdfs:seeAlso "USDA: 48W5.21", "violinID:2862;2864;2861;2863" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002431, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002286 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.22)" ; rdfs:seeAlso "USDA: 48W5.22", "violinID:2866;2868;2865;2867" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002431, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002287 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western & Venezuelan, Killed Virus Vaccine-Tetanus Toxoid (USDA: 48W5.23)" ; rdfs:seeAlso "USDA: 48W5.23", "violinID:2870;2872;2871;2873;2869" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002431, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002288 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Encephalomyelitis-West Nile Virus Eastern & Western, Killed Virus, Live Canarypox Vector Vaccine-Tetanus Toxoid (USDA: 48W9.R0)" ; rdfs:seeAlso "USDA: 48W9.R0", "violinID:2874;2876;2875;2877" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002431, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002289 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Killed Virus Vaccine-Ehrlichia Risticii Bacterin (USDA: 4905.20)" ; rdfs:seeAlso "USDA: 4905.20", "violinID:3010" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002476, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0001119 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002290 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4906.20)" ; rdfs:seeAlso "USDA: 4906.20", "violinID:2922;2923" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002291 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 4960.00)" ; rdfs:seeAlso "USDA: 4960.00", "violinID:2952;2951" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002463, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002292 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.01)" ; rdfs:seeAlso "USDA: 4975.01", "violinID:2946;2945" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002462, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002293 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.20)" ; rdfs:seeAlso "USDA: 4975.20", "violinID:2948;2947" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002462, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002294 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4975.22)" ; rdfs:seeAlso "USDA: 4975.22", "violinID:2950;2949" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002462, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002295 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parainfluenza 3 Modified Live Virus Vaccine-Leptospira Pomona Bacterin (USDA: 4989.00)" ; rdfs:seeAlso "USDA: 4989.00", "violinID:2920;2921" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002459, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002296 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trichomonas Foetus Vaccine, Killed Protozoa-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4990.00)" ; rdfs:seeAlso "USDA: 4990.00", "violinID:3036;3035;3037" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0002481, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002297 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4993.20)" ; rdfs:seeAlso "USDA: 4993.20", "violinID:3012;3011" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002478, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002298 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae Bacterin (USDA: 4993.21)" ; rdfs:seeAlso "USDA: 4993.21", "violinID:3014;3013" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002478, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002299 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.20)" ; rdfs:seeAlso "USDA: 4994.20", "violinID:3016;3015;3017" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002479, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002300 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.21)" ; rdfs:seeAlso "USDA: 4994.21", "violinID:3018;3020;3019" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002479, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002301 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.23)" ; rdfs:seeAlso "USDA: 4994.23", "violinID:3022;3021;3023" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002479, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002302 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin (USDA: 4994.24)" ; rdfs:seeAlso "USDA: 4994.24", "violinID:3024;3026;3025" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002479, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002303 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.22)" ; rdfs:seeAlso "USDA: 4995.22", "violinID:3028;3027" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002480, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002304 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.23)" ; rdfs:seeAlso "USDA: 4995.23", "violinID:3030;3029" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002480, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002305 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.25)" ; rdfs:seeAlso "USDA: 4995.25", "violinID:3032;3031" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002480, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002306 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 4995.26)" ; rdfs:seeAlso "USDA: 4995.26", "violinID:3034;3033" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002480, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002307 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 49B1.21)" ; rdfs:seeAlso "USDA: 49B1.21", "violinID:3004;3006;3003;3005" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002469, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002308 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus Modified Live Virus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid (USDA: 49C1.21)" ; rdfs:seeAlso "USDA: 49C1.21", "violinID:2992;2991;2993" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002471, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002309 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.22)" ; rdfs:seeAlso "USDA: 49F6.22", "violinID:2954;2956;2953;2955" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002464, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002310 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.23)" ; rdfs:seeAlso "USDA: 49F6.23", "violinID:2958;2960;2957;2959" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002464, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002311 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49F6.24)" ; rdfs:seeAlso "USDA: 49F6.24", "violinID:2962;2964;2961;2963" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002464, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002312 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.22)" ; rdfs:seeAlso "USDA: 49G6.22", "violinID:2966;2968;2965;2967" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002465, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002313 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.23)" ; rdfs:seeAlso "USDA: 49G6.23", "violinID:2970;2972;2969;2971" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002465, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002314 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus-Swine Influenza H1N1 & H3N2, Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 49G6.24)" ; rdfs:seeAlso "USDA: 49G6.24", "violinID:2974;2976;2973;2975" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002465, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002315 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus Modified Live Virus Vaccine-Escherichia Coli Bacterin (USDA: 49K1.20)" ; rdfs:seeAlso "USDA: 49K1.20", "violinID:2994;2995" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002474, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002316 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Circovirus Type 2, Killed Baculovirus Vector Vaccine- Mycoplasma Hyopneumoniae Bacterin (USDA: 49K5.R1)" ; rdfs:seeAlso "USDA: 49K5.R1", "violinID:2978;2977" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002467, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002317 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome-Circovirus Reproductive & Respiratory Form, Type 2, Modifed Live Virus,Killed Baculovirus Vector Vaccine-Mycoplasma Hyopneumoniae Bacterin (USDA: 49K9.R0)" ; rdfs:seeAlso "USDA: 49K9.R0", "violinID:2986;2984;2985" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002472, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_85708 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002318 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Escherichia Coli Bacterin (USDA: 49P1.20)" ; rdfs:seeAlso "USDA: 49P1.20", "violinID:3008;3007;3009" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002470, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002319 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Modified Live Virus Vaccine-Bordetella Bronchiseptica-Clostridium Perfringens Type C-Erysipelothrix Rhusiopathiae-Escherichia Coli-Pasteurella Multocida Bacterin-Toxoid (USDA: 49T9.21)" ; rdfs:seeAlso "USDA: 49T9.21", "violinID:3002;2996;2998;3000;2997;2999;3001" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002468, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002320 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infectious Salmon Anemia Virus Killed Virus Vaccine-Aeromonas Salmonicida-Vibrio Anguillarum-Ordalii-Salmonicida Bacterin (USDA: 4A45.20)" ; rdfs:seeAlso "USDA: 4A45.20", "violinID:2878;2880;2879" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0002442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002321 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.20)" ; rdfs:seeAlso "USDA: 4BC5.20", "violinID:2924;2926;2925" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002460, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002322 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.21)" ; rdfs:seeAlso "USDA: 4BC5.21", "violinID:2928;2927;2929" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002460, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0002323 obo:IAO_0000116 "generated using OntoRat" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4BC5.22)" ; rdfs:seeAlso "USDA: 4BC5.22", "violinID:2930;2932;2931" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002460, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000841 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002324 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome-Parvovirus Reproductive Form, Modified Live & Killed Virus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin (USDA: 4P19.20)" ; rdfs:seeAlso "USDA: 4P19.20", "violinID:2988;2990;2987;2989" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002473, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002325 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian encephalomyelitis-chicken anemia virus-fowl pox vaccine" ; rdfs:subClassOf obo:VO_0002326, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12618 ] . obo:VO_0002326 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian encephalomyelitis-fowl pox vaccine" ; rdfs:subClassOf obo:VO_0000985, obo:VO_0001522, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ] . obo:VO_0002327 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian encephalomyelitis-fowl pox-laryngotracheitis vaccine" ; rdfs:subClassOf obo:VO_0002326, obo:VO_0002443, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0002328 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian encephalomyelitis-fowl pox-Mycoplasma gallisepticum vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002326, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2096 ] . obo:VO_0002329 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "avian influenza-fowl pox vaccine" ; rdfs:subClassOf obo:VO_0000461, obo:VO_0000985, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ] . obo:VO_0002330 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Parainfluenza 3-Respiratory Syncytial Virus Vaccine" ; rdfs:subClassOf obo:VO_0000990, obo:VO_0001507, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] . obo:VO_0002331 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000987, obo:VO_0001482, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_75985 ] . obo:VO_0002332 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0000768, obo:VO_0002331, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90371 ] . obo:VO_0002333 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae- Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002334 . obo:VO_0002334 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002335 . obo:VO_0002335 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Vaccine-Leptospira Hardjo-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002336 . obo:VO_0002336 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis Vaccine-Leptospira Pomona Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_94063 ] . obo:VO_0002337 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002338, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_75985 ] . obo:VO_0002338 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bovine rhinotracheitis-parainfluenza 3 vaccine" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0000990, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000987 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] ) ] . obo:VO_0002339 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Haemophilus Somnus Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002338, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ] . obo:VO_0002340 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002338, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11246 ] . obo:VO_0002341 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002342 . obo:VO_0002342 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3 Vaccine-Leptospira Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002336, obo:VO_0002338, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] . obo:VO_0002343 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Parainfluenza 3-Respiratory Syncytial Virus Vaccine" ; rdfs:subClassOf obo:VO_0002338, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11246 ] . obo:VO_0002344 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Respiratory Syncytial Virus Vaccine" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, obo:VO_0001507, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0002345 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0002346 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Campylobacter Fetus-Leptospira CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002349, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_196 ] . obo:VO_0002347 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0002337, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ] . obo:VO_0002348 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida-Salmonella Typhimurium Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0000768, obo:VO_0002347, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90371 ] . obo:VO_0002349 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002350 . obo:VO_0002350 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002351 . obo:VO_0002351 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Hardjo-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002352 . obo:VO_0002352 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea Vaccine-Leptospira Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002336, obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ] . obo:VO_0002353 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine" ; rdfs:subClassOf obo:VO_0002338, obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] . obo:VO_0002354 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002338, obo:VO_0002352, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_196 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] . obo:VO_0002355 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002488 . obo:VO_0002356 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Grippotyphosa-Hardjo-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002488, [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002357 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002358, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_75985 ] . obo:VO_0002358 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine" ; rdfs:subClassOf obo:VO_0002338, obo:VO_0002372, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] . obo:VO_0002359 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Campylobacter Fetus-Haemophilus Somnus-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002360, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000570 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002360 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_196 ] . obo:VO_0002361 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002358, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ] . obo:VO_0002362 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0002361, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0002363 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Haemophilus Somnus-Mannheimia Haemolytica Bacterin" ; rdfs:subClassOf obo:VO_0002357, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ] . obo:VO_0002364 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002368, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ] . obo:VO_0002365 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "chicken bursal disease-Newcastle disease vaccine" ; rdfs:subClassOf obo:VO_0001222, obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560319 ] . obo:VO_0002366 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona-Mannheimia Haemolytica Bacterin" ; rdfs:subClassOf obo:VO_0002364, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_75985 ] . obo:VO_0002367 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis Vaccine" ; rdfs:subClassOf obo:VO_0001502, obo:VO_0002365, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] . obo:VO_0002368 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Leptospira Hardjo Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0002358, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0002369 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica Toxoid" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002358, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_75985 ] . obo:VO_0002370 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus Vaccine-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0002371 . obo:VO_0002371 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3-Respiratory Syncytial Virus-Mannheimia Haemolytica-Pasteurella Multocida Vaccine" ; rdfs:subClassOf obo:VO_0002369, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ] . obo:VO_0002372 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Vaccine" ; rdfs:subClassOf obo:VO_0002345, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11246 ] . obo:VO_0002373 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Respiratory Syncytial Virus Vaccine-Leptospira Pomona Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0002372, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_94063 ] . obo:VO_0002374 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Vaccine" ; rdfs:subClassOf obo:VO_0000658, obo:VO_0001503, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10927 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11128 ] . obo:VO_0002375 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0002377, obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_79668 ] . obo:VO_0002376 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Vaccine-Clostridium Perfringens Types C & D-Escherichia Coli Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0002375 . obo:VO_0002377 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rotavirus-Coronavirus Vaccine-Escherichia Coli Bacterin" ; rdfs:subClassOf obo:VO_0000041, obo:VO_0000586, obo:VO_0002374, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_562 ] . obo:VO_0002378 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Vaccine-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_196 ] . obo:VO_0002379 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Vaccine-Haemophilus Somnus-Mannheimia Haemolytica-Pasteurella Multocida Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001501, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_75985 ] . obo:VO_0002380 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002381 . obo:VO_0002381 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea Vaccine-Leptospira Pomona Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_94063 ] . obo:VO_0002382 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Mareks Disease Vaccine" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10390 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0002383 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bursal Disease-Newcastle Disease-Bronchitis-Reovirus Vaccine" ; rdfs:subClassOf obo:VO_0002367, obo:VO_0003541, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ] . obo:VO_0002384 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "chicken Bursal Disease-Newcastle Disease-Reovirus Vaccine" ; rdfs:subClassOf obo:VO_0002365, obo:VO_0003541, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ] . obo:VO_0002385 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "chicken bursal disease-reovirus vaccine" ; rdfs:subClassOf obo:VO_0001497, obo:VO_0003541, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ] . obo:VO_0002386 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000587, obo:VO_0001490, obo:VO_0001526, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_518 ] . obo:VO_0002387 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-GrippotyphosaIcterohaemorrhagiae-Pomona Bacterial Extract" ; rdfs:subClassOf obo:VO_0002388 . obo:VO_0002388 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0002392, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0002389 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract" ; rdfs:subClassOf obo:VO_0002390, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ] . obo:VO_0002390 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ; rdfs:subClassOf obo:VO_0002391, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_211880 ] . obo:VO_0002391 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90062 ] . obo:VO_0002392 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus Vaccine-Borrelia Burgdorferi Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0003518, obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0002393 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Coronavirus-Parvovirus Vaccine" ; rdfs:subClassOf obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ] . obo:VO_0002394 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2 Vaccine" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10514 ] . obo:VO_0002395 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine" ; rdfs:subClassOf obo:VO_0002408, obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ] . obo:VO_0002396 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2 Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ; rdfs:subClassOf obo:VO_0002397 . obo:VO_0002397 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2 Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ; rdfs:subClassOf obo:VO_0002391, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10514 ] . obo:VO_0002398 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Borrelia Burgdorferi Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001526, obo:VO_0003518, obo:VO_0004897, obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10514 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ] . obo:VO_0002399 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Borrelia Burgdorferi Bacterin-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract" ; rdfs:subClassOf obo:VO_0002400, obo:VO_0003518, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0002400 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract" ; rdfs:subClassOf obo:VO_0002402 . obo:VO_0002401 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "horse EEV, VEV, WEV encephalomyelitis and West Nile Virus vaccine" ; rdfs:subClassOf obo:VO_0000752, obo:VO_0001498, obo:VO_0001499, obo:VO_0012188, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11021 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11039 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] . obo:VO_0002402 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002403 . obo:VO_0002403 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ; rdfs:subClassOf obo:VO_0002404 . obo:VO_0002404 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract" ; rdfs:subClassOf obo:VO_0001526, obo:VO_0002405, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ] . obo:VO_0002405 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parvovirus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0002417, obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10514 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11153 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90062 ] . obo:VO_0002406 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Measles-Parainfluenza Vaccine" ; rdfs:subClassOf obo:VO_0002407, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11234 ] . obo:VO_0002407 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza Vaccine" ; rdfs:subClassOf obo:VO_0001526, obo:VO_0002394, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ] . obo:VO_0002408 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine" ; rdfs:subClassOf obo:VO_0002407, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ] . obo:VO_0002409 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira CanicolaGrippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract" ; rdfs:subClassOf obo:VO_0002410, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0002410 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira CanicolaGrippotyphosa-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002411 . obo:VO_0002411 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ; rdfs:subClassOf obo:VO_0002412 . obo:VO_0002412 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ; rdfs:subClassOf obo:VO_0002425, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ] . obo:VO_0002413 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus Vaccine" ; rdfs:subClassOf obo:VO_0002394, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ] . obo:VO_0002414 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parvovirus-Rabies Vaccine" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0002413, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0002415 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Hepatitis-Parainfluenza Vaccine" ; rdfs:subClassOf obo:VO_0001526, obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10512 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ] . obo:VO_0002416 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Measles Vaccine" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11234 ] . obo:VO_0002417 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Parvovirus Vaccine" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ] . obo:VO_0002418 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "canine parainfluenza-bordetella bronchiseptica vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000587, obo:VO_0001526, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_518 ] . obo:VO_0002419 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "canine parvovirus vaccine-leptospira canicola icterohaemorrhagiae bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0002420 obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV and WEV encephalomyelitis vaccine-tetanus toxoid" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001498, obo:VO_0003554, obo:VO_0012188, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11021 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11039 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ] [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11021 ] [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11039 ] [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] ) ] . obo:VO_0002421 obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine rhinopneumonitis-influenza vaccine" ; rdfs:subClassOf obo:VO_0001486, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10326 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0002422 obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV and WEV encephalomyelitis-influenza vaccine-tetanus toxoid" ; rdfs:subClassOf obo:VO_0002420, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0002420 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] ) ] . obo:VO_0002423 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV and WEV encephalomyelitis-influenza-West Nile virus vaccine-tetanus toxoid" ; rdfs:subClassOf obo:VO_0000752, obo:VO_0002422, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] . obo:VO_0002424 obo:IAO_0000115 "a viral vaccine against horse EEV, WEV, and VEE viral infections" ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "horse encephalomyelitis EEV, VEV, and WEV combination vaccine" ; rdfs:subClassOf obo:VO_0001498, obo:VO_0001499, obo:VO_0012188, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11021 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11039 ] . obo:VO_0002425 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ; rdfs:subClassOf obo:VO_0001526, obo:VO_0002397, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ] . obo:VO_0002426 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Hepatitis-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0002415, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0002427 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Immunodeficiency-Leukemia Virus Vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11673 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11768 ] . obo:VO_0002428 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV and WEV encephalomyelitis-rhinopneumonitis vaccine-tetanus toxoid" ; rdfs:subClassOf obo:VO_0001486, obo:VO_0002420, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10326 ] . obo:VO_0002429 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV and WEV encephalomyelitis-rhinopneumonitis-influenza vaccine-tetanus toxoid" ; rdfs:subClassOf obo:VO_0002422, obo:VO_0002428, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0002430 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "equine EEV and WEV encephalomyelitis-rhinopneumonitis-influenza-West Nile Virus vaccine-tetanus toxoid" ; rdfs:subClassOf obo:VO_0000752, obo:VO_0002429, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] . obo:VO_0002431 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "horse EEV, VEV, WEV encephalomyelitis-West Nile Virus Vaccine-Tetanus Toxoid" ; rdfs:subClassOf obo:VO_0000541, obo:VO_0002401, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] . obo:VO_0002432 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Chlamydia Psittaci Vaccine" ; rdfs:subClassOf obo:VO_0000586, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11768 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83554 ] . obo:VO_0002433 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia Vaccine" ; rdfs:subClassOf obo:VO_0002440, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10786 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11768 ] . obo:VO_0002434 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Leukemia-Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83554 ] . obo:VO_0002435 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Chlamydia Psittaci Vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002440, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83554 ] . obo:VO_0002436 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia Vaccine" ; rdfs:subClassOf obo:VO_0002440, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10786 ] . obo:VO_0002437 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci Vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83554 ] . obo:VO_0002438 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Chlamydia Psittaci-Rabies Vaccine" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0002437, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0002439 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calici-Panleukopenia-Rabies Vaccine" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0002436, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0002440 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline Rhinotracheitis-Calicivirus Vaccine" ; rdfs:subClassOf obo:VO_0003537, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9685 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10334 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11978 ] . obo:VO_0002441 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis-Mareks Disease Vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10390 ] . obo:VO_0002442 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infectious Salmon Anemia Virus Vaccine-Aeromonas Salmonicida-Vibrio Anguillarum-Ordalii-Salmonicida Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_117565 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_55987 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_641 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_645 ] . obo:VO_0002443 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox-Laryngotracheitis Vaccine" ; rdfs:subClassOf obo:VO_0000985, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf ([ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ] [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] ) ] . obo:VO_0002444 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox-Mareks Disease Vaccine" ; rdfs:subClassOf obo:VO_0000985, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10390 ] . obo:VO_0002445 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Pox-Mycoplasma Gallisepticum Vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000985, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2096 ] . obo:VO_0002446 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mannheimia Haemolytica-Pasteurella Multocida Vaccine" ; rdfs:subClassOf obo:VO_0001523, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ] . obo:VO_0002447 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mareks Disease-Newcastle Disease Vaccine" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560319 ] . obo:VO_0002448 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "chicken Mareks disease-tenosynovitis vaccine" ; rdfs:subClassOf obo:VO_0003541, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10390 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38170 ] . obo:VO_0002449 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper-Enteritis Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0002451, obo:VO_0003543, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ] . obo:VO_0002450 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper-Enteritis Vaccine-Clostridium Botulinum Type C-Pseudomonas Aeruginosa Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0000393, obo:VO_0002449, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0002451 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Enteritis Vaccine-Clostridium Botulinum Type C Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9625 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10792 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0002452 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Enteritis Vaccine-Clostridium Botulinum Type C-Pseudomonas Aeruginosa Bacterin-Toxoid" ; rdfs:seeAlso "SNOMEDCT: 55262006; UMLS_CUI:C0310936" ; rdfs:subClassOf obo:VO_0000393, obo:VO_0002451, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0002453 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease-Bronchitis Vaccine-Salmonella Enteritidis Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000768, obo:VO_0002457, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149539 ] . obo:VO_0002454 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Vaccine-Mycoplasma Gallisepticum Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001222, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9031 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2096 ] . obo:VO_0002455 obo:IAO_0000115 "A viral vaccine that protects against infection with Hirame rhabdovirus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hirame rhabdovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980915 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980915 ] . obo:VO_0002456 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease-Fowl Pox Vaccine" ; rdfs:subClassOf obo:VO_0000985, obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10261 ] . obo:VO_0002457 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Bronchitis Vaccine" ; rdfs:subClassOf obo:VO_0001222, obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] . obo:VO_0002458 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle-Paramyxovirus Vaccine" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_260963 ] . obo:VO_0002459 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bovine parainfluenza 3 vaccine-Leptospira Pomona vaccine" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0000990, obo:VO_0001507, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_94063 ] . obo:VO_0002460 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002461 . obo:VO_0002461 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-HardjoIcterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002462, obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1648 ] . obo:VO_0002462 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus Vaccine-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002463 . obo:VO_0002463 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae vaccine" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0001494, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0002464 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus-Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Bratislava-CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002465 . obo:VO_0002465 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Parvovirus-Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Leptospira CanicolaGrippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002461, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12845 ] . obo:VO_0002466 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus-Rabies Virus Vaccine" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0002408, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0002467 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Circovirus Vaccine- Mycoplasma Hyopneumoniae Bactin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001524, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2099 ] . obo:VO_0002468 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Bordetella Bronchiseptica-Clostridium Perfringens Type C-Erysipelothrix Rhusiopathiae-Escherichia Coli-Pasteurella Multocida Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0002469, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1648 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ] . obo:VO_0002469 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0002471, obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11149 ] . obo:VO_0002470 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Vaccine-Escherichia Coli Bacterin" ; rdfs:subClassOf obo:VO_0002474, obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11149 ] . obo:VO_0002471 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus Vaccine-Clostridium Perfringens Type C-Escherichia Coli Bacterin-Toxoid" ; rdfs:subClassOf obo:VO_0002474, obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1502 ] . obo:VO_0002472 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome-Circovirus Vaccine-Mycoplasma Hyopneumoniae Bacterin" ; rdfs:subClassOf obo:VO_0002467, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0002473 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome-Parvovirus Vaccine-Erysipelothrix Rhusiopathiae-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0001511, obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1648 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0002474 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus Vaccine-Escherichia Coli Bacterin" ; rdfs:subClassOf obo:VO_0000041, obo:VO_0000586, obo:VO_0001495, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_562 ] . obo:VO_0002475 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Rotavirus-Transmissible Gastroenteritis Vaccine" ; rdfs:subClassOf obo:VO_0001495, obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11149 ] . obo:VO_0002476 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies Vaccine-Ehrlichia Risticii Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000650, obo:VO_0003550, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_950 ] . obo:VO_0002477 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza Vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:NCBITaxon_12845 obo:NCBITaxon_36420 ) ] ] . obo:VO_0002478 obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002477, obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1648 ] . obo:VO_0002479 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza Vaccine-Erysipelothrix Rhusiopathiae-Mycoplasma Hyopneumoniae Bacterin" ; rdfs:subClassOf obo:VO_0002478, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2099 ] . obo:VO_0002480 obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Swine Influenza Vaccine-Mycoplasma Hyopneumoniae Bacterin" ; rdfs:seeAlso "USDA: 4995.22", "violinID:3028;3027" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0002477, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2099 ] . obo:VO_0002481 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trichomonas Foetus-Campylobacter Fetus-Leptospira vaccine" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0001457, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_196 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_56690 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_171 obo:NCBITaxon_196 obo:NCBITaxon_56690 ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_171 obo:NCBITaxon_196 obo:NCBITaxon_56690 ) ] ] . obo:VO_0002482 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Coronavirus-Parvovirus Vaccine" ; rdfs:subClassOf obo:VO_0002393, obo:VO_0003543, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ] . obo:VO_0002483 obo:IAO_0000115 "A horse vaccine that protects against EEE, VEE, WEE, influenza virius infection, and West Nile virus infection. " ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "horse Encephalomyelitis-Influenza-West Nile Virus vaccine" ; rdfs:subClassOf obo:VO_0000752, obo:VO_0001498, obo:VO_0001499, obo:VO_0012188, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11021 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11039 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0002484 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mink Distemper-Enteritis Vaccine" ; rdfs:subClassOf obo:VO_0003543, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9625 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10792 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ] . obo:VO_0002485 obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "porcine parvovirus-erysipelothrix rhusiopathiae vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001494, obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9823 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10796 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1648 ] . obo:VO_0002486 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Virus Diarrhea-Respiratory Syncytial Virus Vaccine" ; rdfs:subClassOf obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11246 ] . obo:VO_0002487 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterial Extract" ; rdfs:subClassOf obo:VO_0002403, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9612 ] . obo:VO_0002488 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Leptospira Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002338, obo:VO_0002352, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052729 ] . obo:VO_0002489 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Respiratory Syncytial Virus Virus Vaccine-Haemophilus somnus Bacterin" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001507, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_731 ] . obo:VO_0002490 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza 3 Vaccine-Haemophilus somnus-Campylobacter Fetus-Leptospira Canicola-Grippotyphosa-Hardjo-Icterohaemorrhagiae-Pomona Bacterin" ; rdfs:subClassOf obo:VO_0002354, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_196 ] . obo:VO_0002491 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Modified Live Virus & Avirulent Live Culture Vaccine (USDA: 12X1.21)" ; rdfs:seeAlso "USDA: 12X1.21" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002386, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002492 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Distemper-Adenovirus Type 2-Coronavirus-Parainfluenza-Parvovirus Modified Live & Killed Virus Vaccine-Leptospira Icterohaemorrhagiae Bacterial Extract (USDA: 46L9.20)" ; rdfs:seeAlso "USDA: 46L9.20" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000712, obo:VO_0001214, obo:VO_0001485, obo:VO_0002404, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002493 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fowl Laryngotracheitis-Marek's Disease Serotype 3, Live Marek's Disease Vector Vaccine (USDA: 16J1.R3)" ; rdfs:seeAlso "USDA: 16J1.R3" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0002441, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0002494 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment """created according to WHO Technical Report Series, No. 927, 2005 Annex 3 Recommendations for the production and control of influenza vaccine (inactivated)""" ; rdfs:label "influenza vaccine (whole virion, inactivated)" ; rdfs:subClassOf obo:VO_0001176 . obo:VO_0002495 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment """created according to WHO Technical Report Series, No. 927, 2005 Annex 3 Recommendations for the production and control of influenza vaccine (inactivated)""" ; rdfs:label "influenza vaccine (split virion, inactivated)" ; rdfs:subClassOf obo:VO_0001176 . obo:VO_0002496 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment """created according to WHO Technical Report Series, No. 927, 2005 Annex 3 Recommendations for the production and control of influenza vaccine (inactivated)""" ; rdfs:label "influenza vaccine (surface antigens, inactivated)" ; rdfs:subClassOf obo:VO_0001176 . obo:VO_0002497 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment """created according to WHO Technical Report Series, No. 927, 2005 Annex 3 Recommendations for the production and control of influenza vaccine (inactivated)""" ; rdfs:label "influenza vaccine (inactivated, adjuvanted)" ; rdfs:subClassOf obo:VO_0001176 . obo:VO_0002498 obo:IAO_0000117 "YL" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:comment """GSK Acquires Influenza Vaccine Manufacturer ID Biomedical Corporation http://www.medicalnewstoday.com/releases/34803.php GlaxoSmithKline plc (NYSE:GSK) announced the completion of the acquisition of ID Biomedical. This follows regulatory clearances of the transaction and adoption of the acquisition agreement by ID Biomedical's shareholders (which occurred on the 16th of November). ID Biomedical becomes a wholly-owned subsidiary of GSK. ...""" ; rdfs:label "ID Biomedical Corporation of Quebec" . obo:VO_0002499 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H1N1) 2009 Monovalent Vaccine (IDB)" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, obo:VO_0003211, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0002498 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:VO_0000908 ] . obo:VO_0002500 obo:IAO_0000115 "A vaccine that protects against Listeria monocytogenes." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Listeria monocytogenes vaccine" ; rdfs:subClassOf obo:VO_0003555, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1639 ] . obo:VO_0002501 obo:IAO_0000115 "A vaccine that protects against Mycobacterium avium." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycobacterium avium vaccine" ; rdfs:subClassOf obo:VO_0000592, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1764 ] . obo:VO_0002502 obo:IAO_0000115 "A bacterial vaccine that protects against infection with Staphylococcus aureus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Staphylococcus aureus vaccine" ; rdfs:subClassOf obo:VO_0000770, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0002503 obo:IAO_0000115 "A bacterial gene that is from Streptococcus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Streptococcus gene" ; rdfs:subClassOf obo:OGG_2000000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_1279 ] . obo:VO_0002504 obo:IAO_0000115 "A bacterial gene that is from Streptococcus equi." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Streptococcus equi gene" ; rdfs:subClassOf obo:VO_0002503, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_1336 ] . obo:VO_0002505 obo:IAO_0000115 "An Aeromonas vaccine that protects against Aeromonas hydrophila." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Aeromonas hydrophila vaccine" ; rdfs:subClassOf obo:VO_0000589, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_644 ] . obo:VO_0002506 obo:IAO_0000115 "An Edwardsiella bacterial vaccine that protects against Edwardsiella tarda." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Edwardsiella tarda vaccine" ; rdfs:subClassOf obo:VO_0000602, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_636 ] . obo:VO_0002507 obo:IAO_0000115 "A bacterial vaccine that protects against infections by Salmonella typhimurium species." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella typhimurium vaccine" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90371 ] . obo:VO_0002508 obo:IAO_0000115 "A bacterial vaccine that protects against infections by Salmonella enterica subsp. enterica serovar Gallinarum." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella gallinarum vaccine" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_594 ] . obo:VO_0002509 obo:IAO_0000115 "A bacterial vaccine that protects against infections by Salmonella enterica subsp. enterica serovar Enteritidis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella enteritidis vaccine" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149539 ] . obo:VO_0002510 obo:IAO_0000115 "A bacterial vaccine that protects against infections by Yersinia pseudotuberculosis." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yersinia pseudotuberculosis vaccine" ; rdfs:subClassOf obo:VO_0000601, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_633 ] . obo:VO_0002511 obo:IAO_0000115 "A viral vaccine that protects against infection of Human metapneumovirus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human metapneumovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_162145 ] . obo:VO_0002512 obo:IAO_0000115 "A viral vaccine that protects against infection of Human respiratory syncytial virus." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human respiratory syncytial virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11250 ] . obo:VO_0002513 obo:IAO_0000115 "a malaria vaccine that protects against malaria caused by Plasmodium berghei." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Plasmodium berghei vaccine" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5821 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5821 ] . obo:VO_0002514 obo:IAO_0000115 "a malaria vaccine that protects against malaria caused by Plasmodium yoelii." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Plasmodium yoelii vaccine" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5861 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000761 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5861 ] ) ] . obo:VO_0002515 obo:IAO_0000115 "A protozoan gene that is from Leishmania infantum." ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:label "Leishmania infantum gene" ; rdfs:subClassOf obo:VO_0000174, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5671 ] . obo:VO_0002516 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "The mutant strain, with deletion of apxIA gene, obtained in this study offered a level of cross-serovar protection against A. pleuropneumoniae infection in mice and pigs (Reference: PMID: 16930871)." ; rdfs:label "apxIA from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Gene_ID: 4850247; PMID: 16930871" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002517 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "In the intra-peritoneal mouse model, the virulence of the mutant strain decreased at least 100 fold compared with the parent strain. The mutant was evaluated as a potential vaccine using a vaccination-challenge trial. The death number and lung lesion score in the vaccinated pigs given the serovar 1 challenge were obviously lower than those in the unvaccinated pigs" ; rdfs:label "apxIC from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Protein_ID: 1477456; PMID: 18062275" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002518 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Deletion in ureC and apxIIA genes of Actinobacillus pleuropneumoniae serotype 2 prototype provides attenuation and protection in pigs against challenge with the virulent parent strain of A. pleuropneumoniae" ; rdfs:label "apxIIA from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Protein_ID: 255959000; PMID: 12438394" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002519 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002520" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" ; rdfs:label "apxIIC from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Protein_ID: 52630373; PMID: 10085043" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002520 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002519 ; a owl:Class ; rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" ; rdfs:label "obsolete apxIIC from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Protein_ID: 52630373; PMID: 10085043" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002521 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain" ; rdfs:label "apxIIIB from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Nucleotide_ID: 470686; PMID: 19887737" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002522 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain" ; rdfs:label "apxIIID from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Nucleotide_ID: 470687; PMID: 19887737" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002523 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae was constructed based on HB04C(-) by transconjugation and counterselection. The results demonstrated that the DeltaapxIICDeltaapxIVA double mutant strain was less virulent than HB04C(-). Despite attenuation of virulence, the DeltaapxIICDeltaapxIVA double mutant remains immunogenic and conferred a similar level of protective immunity to pigs against challenge with a lethal dose of a heterologous fully virulent standard serovar 1 strain of A. pleuropneumoniae" ; rdfs:label "apxIVA from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Protein_ID: 6671152; PMID: 17767980" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002524 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application" ; rdfs:label "ureC from Actinobacillus pleuropneumoniae" ; rdfs:seeAlso "NCBI_Protein_ID: 303253439; PMID: 12438394" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002525 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An mntA deletion mutant, generated by allelic replacement, in Bacillus anthracis was attenuated and provided protection for guinea pigs against lethal spore dose (60 LD50) of the virulent B. anthracis Vollum strain" ; rdfs:label "mntA from Bacillus anthracis" ; rdfs:seeAlso "NCBI_Gene_ID: 7848141; PMID: 16194238" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001402, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002526 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002527" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes" ; rdfs:label "actA from Listeria monocytogenes" ; rdfs:seeAlso "NCBI_Gene_ID: 987035; PMID: 12763691" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001403, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002527 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002526 ; a owl:Class ; rdfs:comment "An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes" ; rdfs:label "obsolete actA from Listeria monocytogenes" ; rdfs:seeAlso "NCBI_Gene_ID: 987035; PMID: 12763691" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002528 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A plcB mutant, in combination with an actA mutant, is attenuated in mice and induces significant protection from challenge with wild type L. monocytogenes" ; rdfs:label "plcB from Listeria monocytogenes" ; rdfs:seeAlso "NCBI_Gene_ID: 987036; PMID: 12763691" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001403, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002529 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A M. avium relA mutant is attenuated in calves and goats. This mutant also elicited an immune response in goats that limited colonization by challenge wild type M. avium" ; rdfs:label "relA from Mycobacterium avium" ; rdfs:seeAlso "NCBI_Gene_ID: 2717869; PMID: 21565243" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001404, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002530 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A drrC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "drrC from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 888491; PMID: 14702160" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002531 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An fadD26 mutant is attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "fadD26 from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 887603; PMID: 15958066" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002532 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Deletion of leuD gene was shown to be highly attenuated. Immunocompetent BALB/c mice vaccinated with the DleuD auxotroph were protected as well as BCG in terms of survival following an intravenous or aerosol challenge with virulent M. tuberculosis" ; rdfs:label "leuD from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 888225; PMID: 10768986" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002533 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A lysA mutant, in combination with a secA2 mutation, is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "lysA from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 886960; PMID: 21264335" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002534 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A Mce-2 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice" ; rdfs:label "mce-2 from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 925014; PMID: 16388878" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002535 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A mce-3 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice" ; rdfs:label "mce-3 from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 923491; PMID: 16388878" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002536 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002537" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "panC from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 885459; PMID: 12219086" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002537 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002536 ; a owl:Class ; rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "obsolete panC from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 885459; PMID: 12219086" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002538 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002539" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "panD from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 885596; PMID: 12219086" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002539 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002538 ; a owl:Class ; rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "obsolete panD from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 885596; PMID: 12219086" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002540 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls" ; rdfs:label "phoP from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 888772; PMID: 19367339" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002541 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A proC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis that is equal to the protection induced by the current vaccine BCG" ; rdfs:label "proC from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 887256; PMID: 11160012" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002542 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "RD1 and panCD mutants in Mycobacterium tuberculosis were attenuated and provided protection in CD4-deficient mice against an aerosol challenge with virulent M. tuberculosis" ; rdfs:label "RD1 from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 885777; PMID: 16860907" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002543 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Gu√©rin vaccination" ; rdfs:label "secA2 from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 885594; PMID: 17671656" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002544 obo:IAO_0000115 "A viral vaccine that protects against infection with Reticuloendotheliosis virus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Reticuloendotheliosis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11636 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11636 ] . obo:VO_0002545 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A sigE mutant is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis, more so than the existing vaccine BCG" ; rdfs:label "sigE from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 888751; PMID: 20457786" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002546 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A trpD mutant is highly attenuated in mice and induces more protection from challenge with wild type M. tuberculosis than that induced by the current vaccine BCG" ; rdfs:label "trpD from Mycobacterium tuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 887681; PMID: 11160012" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000164, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002547 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. aureus" ; rdfs:label "aroA from Staphylococcus aureus" ; rdfs:seeAlso "NCBI_Gene_ID: 8614197; PMID: 16714581" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001405, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002548 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A vicK mutant is attenuated in mice and induced protection from challenge with wild type S. equi" ; rdfs:label "vicK from Streptococcus equi" ; rdfs:seeAlso "NCBI_Gene_ID: 6760966; PMID: 19088917" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0002504, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002549 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An A. hydrophila aroA mutant is highly attenuated in trout, and a single immunization conferred significant protection from challenge with wild type A. hydrophila" ; rdfs:label "aroA from Aeromonas hydrophila" ; rdfs:seeAlso "NCBI_Gene_ID: 4489425; PMID: 9573055" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001406, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002550 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice" ; rdfs:label "aroA from Aeromonas salmonicida" ; rdfs:seeAlso "NCBI_Gene_ID: 4997369; PMID: 8478107" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001408, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002551 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002552" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract" ; rdfs:label "aroA from Bordetella bronchiseptica" ; rdfs:seeAlso "NCBI_Gene_ID: 2659145; PMID: 12009288" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001407, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002552 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002551 ; a owl:Class ; rdfs:comment "Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract" ; rdfs:label "obsolete aroA from Bordetella bronchiseptica" ; rdfs:seeAlso "NCBI_Gene_ID: 2659145; PMID: 12009288" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002553 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 √ó 105 CFU of RB50, the B. Bronchiseptica parent strain" ; rdfs:label "bscN from Bordetella bronchiseptica" ; rdfs:seeAlso "NCBI_Gene_ID: 2662485; PMID: 17452472" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001407, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002554 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 √ó 105 CFU of RB50, the B. Bronchiseptica parent strain" ; rdfs:label "cyaA from Bordetella bronchiseptica" ; rdfs:seeAlso "NCBI_Gene_ID: 2661688; PMID: 17452472" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001407, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002555 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A dnt mutant in Bordetella bronchiseptica was attenuated and provides protection in guinea pigs against intranasal challenge with strain L3" ; rdfs:label "dnt from Bordetella bronchiseptica" ; rdfs:seeAlso "NCBI_Gene_ID: 2661538; PMID: 3182989" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001407, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002556 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A trpE mutant, in combination with an aroA mutation, is attenuated in mice and induces significant protection from challenge with wild type B. bronchiseptica" ; rdfs:label "trpE from Bordetella bronchiseptica" ; rdfs:seeAlso "NCBI_Protein_ID: 8515760; PMID: 12694904" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001407, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002557 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in mice and induces significant protection from challenge with wild type B. pertussis" ; rdfs:label "aroA from Bordetella pertussis" ; rdfs:seeAlso "NCBI_Protein_ID: 144037; PMID: 2407655" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001409, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002558 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A live attenuated B. pertussis vaccine strain BPZE1, developed by deleting dnt gene, protects mice upon a single intranasal administration" ; rdfs:label "dnt from Bordetella pertussis" ; rdfs:seeAlso "NCBI_Gene_ID: 2666936; PMID: 18762220" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001409, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002559 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A flagella-less mutant of Borrelia burgdorferi (HB19Fla-) was attenuated in immunodeficient SCID mice. Mice were challenged 28 days later with virulent strain Sh. 2 and were protected from challenge" ; rdfs:label "fla from Borrelia burgdorferi" ; rdfs:seeAlso "NCBI_Protein_ID: 435009; PMID: 8627071" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001410, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002560 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A asp24 mutation in Brucella abortus is attenuated and provides significant protection in mice" ; rdfs:label "asp24 from B. abortus" ; rdfs:seeAlso "NCBI_Protein_ID: 2353000; PMID: 17664263" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000793, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002561 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A bp26 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice" ; rdfs:label "bp26 from B. melitensis" ; rdfs:seeAlso "NCBI_Protein_ID: 265991532; PMID: 15246618" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002562 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Brucella DeltaexsA mutant showed decreased survival in mice compared to the survival of parental strain S2308. This demonstrated that ExsA is critical for full bacterial virulence. The B. abortus exsA deletion mutant was used as a live vaccine candidate. Challenge experiments revealed that the exsA mutant strain induced superior protective immunity in BALB/c mice compared to the protective immunity induced by strain S19 or RB51" ; rdfs:label "exsA from B. abortus" ; rdfs:seeAlso "NCBI_Gene_ID: 3787220; PMID: 12183550" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000793, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002563 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice" ; rdfs:label "manA from B. melitensis" ; rdfs:seeAlso "NCBI_Protein_ID: 260563601; PMID: 16790778" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002564 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Mutants manB and manA were attenuated in Brucella melitensis and provided protection against challenge in mice's livers" ; rdfs:label "manB from B. melitensis" ; rdfs:seeAlso "NCBI_Gene_ID: 1198671; PMID: 17664263" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002565 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A mucR mutant has a significantly reduced degree of colonization in mice and protects against wild type B. melitensis 16M" ; rdfs:label "mucR from B. melitensis" ; rdfs:seeAlso "NCBI_Gene_ID: 1197075; PMID: 21708998" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002566 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A omp25 mutant is attenuated and provides protection against challenge in mice" ; rdfs:label "omp25 from B. melitensis" ; rdfs:seeAlso "NCBI_Gene_ID: 1196960; PMID: 12151196" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002567 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A omp31 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice" ; rdfs:label "omp31 from B. melitensis" ; rdfs:seeAlso "NCBI_Gene_ID: 7676420; PMID: 15246618" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002568 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A pgk mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus" ; rdfs:label "pgk from B. abortus" ; rdfs:seeAlso "NCBI_Gene_ID: 3788256; PMID: 20194591" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000793, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002569 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A pgm mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus" ; rdfs:label "pgm from B. abortus" ; rdfs:seeAlso "NCBI_Gene_ID: 3788847; PMID: 14573645" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000793, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002570 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Mice infected with delta purE201 developed only five to eight times normal spleen weight at 1 week p.i. and produced no interleukin-6 in their serum, which is much lower than the mice infected with the parental strain (16M)" ; rdfs:label "purE from B. melitensis" ; rdfs:seeAlso "NCBI_Gene_ID: 1196006; PMID: 8675325" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002571 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A purE/purK mutant of B. melitensis 16M was attenuated in mice when given intraperitoneally. Nine weeks after immunization, mice were protected from challenge with wild type B. melitensis" ; rdfs:label "purK from B. melitensis" ; rdfs:seeAlso "NCBI_Protein_ID: 20141763; PMID: 7642258" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002572 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A virB2 mutant is attenuated in Brucella melitensis and provides protection in mice" ; rdfs:label "virB2 from B. abortus" ; rdfs:seeAlso "NCBI_Gene_ID: 3827981; PMID: 17664263" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000793, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002573 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "The deletion of vjbR gene in Brucella melitensis strain 16M made a live attenuated vaccine and provided significance protection against mice" ; rdfs:label "vjbR from B. melitensis" ; rdfs:seeAlso "NCBI_Gene_ID: 1198888; PMID: 21530111" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001400, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002574 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Deletion of gene znuA attenuates Brucella abortus and this live attenuated vaccine was challenged in mice. These mice showed significantly fewer spenic CFU" ; rdfs:label "znuA from Brucella spp." ; rdfs:seeAlso "NCBI_Gene_ID: 3827700; PMID: 16790759" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000793, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002575 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "The aroC deletion in the resultant mutant, designated A2ŒîaroC, was confirmed by PCR, Southern hybridization and failure of the mutant to grow in a defined medium without aromatic compounds. The constructed unmarked aroC mutant of B. pseudomallei is attenuated in both BALB/c and C57Bl/6 mice and is able to confer significant protection in C57Bl/6 mice" ; rdfs:label "aroC from Burkholderia pseudomallei" ; rdfs:seeAlso "NCBI_Gene_ID: 4899749; PMID: 19323044" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001411, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002576 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An asd mutant is highly attenuated in mice. This mutant was also able to protect against acute inhalation melioidosis caused by challenge with wild type B. pseudomallei" ; rdfs:label "asd from Burkholderia pseudomallei" ; rdfs:seeAlso "NCBI_Protein_ID: 2358232; PMID: 21807903" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001411, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002577 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Mice that were challenged with a higher dose of mutant 56:65 purM were protected" ; rdfs:label "purM from Burkholderia pseudomallei" ; rdfs:seeAlso "NCBI_Gene_ID: 3092877; PMID: 19121696" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001411, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002578 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Although 30:93a purN -immunized mice were challenged with a 10-fold higher dose of WT E8, mice were strongly protected and showed no signs of clinical illness until the experiment was terminated" ; rdfs:label "purN from Burkholderia pseudomallei" ; rdfs:seeAlso "NCBI_Gene_ID: 3092878; PMID: 19121696" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001411, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002579 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A crp mutant is attenuated in zebrafish and catfish that were immunized intramuscularly and intracoelomically, respectively. Six weeks after immunization, both zebrafish and catfish were protected from challenge with wild type E. ictaluri" ; rdfs:label "crp from Edwardsiella ictaluri" ; rdfs:seeAlso "NCBI_Gene_ID: 7962173; PMID: 22015784" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001412, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002580 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002581", "VO:0002582" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" ; rdfs:label "aroC from Edwardsiella tarda" ; rdfs:seeAlso "NCBI_Gene_ID: 8608790; PMID: 21777261" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001413, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002581 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002580 ; a owl:Class ; rdfs:comment "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" ; rdfs:label "obsolete aroC from Edwardsiella tarda" ; rdfs:seeAlso "NCBI_Gene_ID: 8608790; PMID: 21777261" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002582 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002580 ; a owl:Class ; rdfs:comment "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" ; rdfs:label "obsolete aroC from Edwardsiella tarda" ; rdfs:seeAlso "NCBI_Gene_ID: 8608790; PMID: 21777261" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002583 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An esrB mutant is highly attenuated in fish (turbot), with an LD50 of 10(8.1)cfu/fish. Vaccination with this mutant elicited significant protection from wild type E. tarda" ; rdfs:label "esrB from Edwardsiella tarda" ; rdfs:seeAlso "NCBI_Gene_ID: 8607237; PMID: 17478097" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001413, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002584 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%" ; rdfs:label "esrC from Edwardsiella tarda" ; rdfs:seeAlso "NCBI_Gene_ID: 8607212; PMID: 21777261" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001413, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002585 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%" ; rdfs:label "slyA from Edwardsiella tarda" ; rdfs:seeAlso "NCBI_Gene_ID: 8608031; PMID: 21777261" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001413, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002586 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli" ; rdfs:label "carA from Escherichia coli" ; rdfs:seeAlso "NCBI_Gene_ID: 949025; PMID: 8063392" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000161, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002587 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli" ; rdfs:label "carB from Escherichia coli" ; rdfs:seeAlso "NCBI_Gene_ID: 944775; PMID: 8063392" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000161, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002588 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A ler deletion mutant derived from wild-type EHEC O157:H7 86-24 was constructed by use of suicide vector pCVD442. Following challenge of 7-day-old suckling mice with O157:H7 EDL933, 75.2% born to group B mothers (immunized with F25) sur- vived, as did 83.0% born to group C mothers (immunized with F105). The surviving suckling mice consistently gained body weight. Only 16.8% of sucking mice born to control group mice survived the challenge" ; rdfs:label "ler from Escherichia coli" ; rdfs:seeAlso "NCBI_Gene_ID: 8219269; PMID: 19682616" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000161, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002589 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Deletion of waaL results in a strain that stimulates enhanced urothelial cytokine secretion, which is an enhanced innate immune response. Inoculation with the vaccine strain protected mice against challenge with a broad range of clinical uropathogenic E. coli isolates and produced immunity that lasted ‚©æ8 weeks" ; rdfs:label "rfaL from Escherichia coli" ; rdfs:seeAlso "NCBI_Gene_ID: 948148; PMID: 19522648" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000161, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002590 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "There was a deletion in gene capB of F. tularensis live vaccine strain. LVS capB, while much less virulent than LVS, induces potent protective immunity against lethal LVS i.n. challenge in mice, comparable to that induced by LVS" ; rdfs:label "capB from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3952402; PMID: 20643859" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002591 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A clpB mutant in Francisella tularensis subspecies tularensis strain SCHU S4 was attenuated and provided protection against aerosol challenge in mice" ; rdfs:label "clpB from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3192509; PMID: 20018266" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002592 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A FTL0552 mutant in Francisella tularensis was attenuated and provided partial protection in mice against challenge with a lethal dose of the virulent SchuS4 strain when compared to naive mice" ; rdfs:label "FTL0552 from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3952730; PMID: 18613792]" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002593 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An FTT0918 mutant showed significantly reduced virulence in mice. Mice that recovered from infection with the mutant were protected 2 months later from challenge with wild type F. tularensis" ; rdfs:label "FTT0918 from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3191684; PMID: 16299332" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002594 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A galU mutant is attenuated in mice, with only transient weight loss observed. Two months after inoculation, mice were challenge with wild type F. tularensis and were protected, once again only experiencing transient weight loss" ; rdfs:label "galU from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3191600; PMID: 21819572" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002595 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaA mutant is highly attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS" ; rdfs:label "guaA from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3951701; PMID: 19368784" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002596 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaB mutant is attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS" ; rdfs:label "guaB from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3952496; PMID: 19368784" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002597 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS). Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge" ; rdfs:label "iglB from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 4548125; PMID: 20016043" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002598 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An iglC mutant is highly attenuated in mice. Inoculated mice were challenged 30 days later with wild type F. tularensis and were highly protected" ; rdfs:label "iglC from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 4548124; PMID: 16552035" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002599 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A purMCD mutant in Francisela tularensis was attenuated. A low dosage of F. tularensis LVS delta purMCD mutant provided protection against challenge in mice" ; rdfs:label "purC/purD from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3952576; PMID: 16861631" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002600 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Mice, which had been immunized with at least 6.95√ó103 cfu of F. tularensis U112 purF::Cm, were protected against the subsequent F. tularensis subspecies novicida challenge" ; rdfs:label "purF from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 4548578; PMID: 16930871" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002601 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain" ; rdfs:label "purM from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3952575; PMID: 16861631" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002602 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "C57BL/6 mice were vaccinated intranasally (i.n.) with the sodB(Ft) mutant and challenged i.n. with lethal doses of F. tularensis SchuS4. SodB(Ft) vaccinated mice following SchuS4 challenge exhibited significantly reduced bacterial burden in lungs, liver and spleen, regulated production of pro-inflammatory cytokines and less severe histopathological lesions compared to the LVS vaccinated mice. The sodB(Ft) vaccination induced a potent humoral immune response and protection against SchuS4 required both CD4 and CD8 T cells in the vaccinated mice" ; rdfs:label "sodB from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 4548021; PMID: 18692537" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002603 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A sodC mutant in Francisella tularensis subspecies holarctica was attenuated and provided protection and cleared the infection against lethal challenge in nearly 50% of the mice infected with the ŒîsodC mutant" ; rdfs:label "sodC from Francisella tularensis" ; rdfs:seeAlso "NCBI_Protein_ID: 1314283; PMID: 19684141" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002604 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A wbtA mutant in Francisella tularensis was attenuated and provided protection in mice against challenge with an otherwise lethal dose of either F. tularensis LVS or a fully virulent clinical isolate of F. tularensis type B" ; rdfs:label "wbtA from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 3191939; PMID: 17296751" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002605 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A wbtI mutant is attenuated in mice. The mutant protected against a low dose challenge with the parental strain, but was less effective against higher doses. However, increasing the immunization dose increased the resistance to higher challenge doses" ; rdfs:label "wbtI from Francisella tularensis" ; rdfs:seeAlso "NCBI_Gene_ID: 5522688; PMID: 17768257" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001414, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002606 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in mice and induced significant protection after two doses from challenge with wild type M. haemolytica" ; rdfs:label "aroA from Mannheimia haemolytica" ; rdfs:seeAlso "NCBI_Protein_ID: 451485; PMID: 7839583" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001415, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002607 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An lpd mutant is highly attenuated in chickens and induces significant protection from challenge with wild type M. gallisepticum" ; rdfs:label "lpd from Mycoplasma gallisepticum" ; rdfs:seeAlso "NCBI_Gene_ID: 1089767; PMID: 18342996" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001416, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002608 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A metH mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis" ; rdfs:label "metH from Neisseria meningitidis" ; rdfs:seeAlso "NCBI_Gene_ID: 903064; PMID: 14688114" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001417, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002609 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An rfaF mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis" ; rdfs:label "rfaF from Neisseria meningitidis" ; rdfs:seeAlso "NCBI_Gene_ID: 904029; PMID: 14688114" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001417, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002610 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002611" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" ; rdfs:label "siaD from Neisseria meningitidis" ; rdfs:seeAlso "NCBI_Gene_ID: 903210; PMID: 14688114" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001417, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002611 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002610 ; a owl:Class ; rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" ; rdfs:label "obsolete siaD from Neisseria meningitidis" ; rdfs:seeAlso "NCBI_Gene_ID: 903210; PMID: 14688114" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002612 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in calves and induces significant protection from challenge with wild type P. multocida" ; rdfs:label "aroA from Pasteurella multocida" ; rdfs:seeAlso "NCBI_Protein_ID: 581456; PMID: 17875632" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001418, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002613 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. typhi Ty2" ; rdfs:label "aroA from Salmonella Typhi" ; rdfs:seeAlso "NCBI_Gene_ID: 1068996; PMID: 3039297" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001419, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002614 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002615" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ; rdfs:label "aroC from Salmonella Typhi" ; rdfs:seeAlso "NCBI_Gene_ID: 1069415; PMID: 17582563" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001419, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002615 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002614 ; a owl:Class ; rdfs:comment "Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ; rdfs:label "obsolete aroC from Salmonella spp." ; rdfs:seeAlso "NCBI_Gene_ID: 1069415; PMID: 17582563" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002616 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Inactivation of AroD results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ; rdfs:label "aroD from Salmonella Typhi" ; rdfs:seeAlso "NCBI_Gene_ID: 1070649; PMID: 17582563" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001419, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002617 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002618" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium" ; rdfs:label "asd from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 267995764; PMID: 20799091" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002618 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002617 ; a owl:Class ; rdfs:comment "An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium" ; rdfs:label "obsolete asd from Salmonella spp." ; rdfs:seeAlso "NCBI_Protein_ID: 267995764; PMID: 20799091" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002619 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An atpA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ; rdfs:label "atpA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 301160399; PMID: 19649318" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002620 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A cbiA mutant, in combination with a cobS mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis" ; rdfs:label "cbiA from Salmonella Gallinarum" ; rdfs:seeAlso "NCBI_Gene_ID: 6923268; PMID: 20153354" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001420, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002621 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective, and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis" ; rdfs:label "clpP from Salmonella Enteritidis" ; rdfs:seeAlso "NCBI_Gene_ID: 6950532; PMID: 21807911" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002622 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002623", "VO:0002624" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" ; rdfs:label "clpP from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1251968; PMID: 2496146" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002623 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002622 ; a owl:Class ; rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" ; rdfs:label "obsolete clpP from Salmonella spp." ; rdfs:seeAlso "NCBI_Gene_ID: 1251968; PMID: 2496146" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002624 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002622 ; a owl:Class ; rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" ; rdfs:label "obsolete clpP from Salmonella spp." ; rdfs:seeAlso "NCBI_Gene_ID: 1251968; PMID: 2496146" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002625 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis" ; rdfs:label "cobS from Salmonella Gallinarum" ; rdfs:seeAlso "NCBI_Gene_ID: 6923296; PMID: 20153354" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001420, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002626 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ; rdfs:label "cpxA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1255585; PMID: 15542179" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002627 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A cpxR mutant, in combination with a lon mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ; rdfs:label "cpxR from Salmonella Gallinarum" ; rdfs:seeAlso "NCBI_Gene_ID: 6923307; PMID: 20487719" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001420, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002628 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium" ; rdfs:label "crp from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1254989; PMID: 3316029" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002629 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A crp mutant is attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ; rdfs:label "crp from Salmonella Gallinarum" ; rdfs:seeAlso "NCBI_Protein_ID: 46811321; PMID: 17488512" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001420, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002630 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium" ; rdfs:label "cya from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 581756; PMID: 3316029" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002631 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A fliC mutant, in combination with a guaB mutant, is attenuated in mice and chickens and induces significant protection from challenge with wild type S. enterica" ; rdfs:label "fliC from Salmonella Enteritidis" ; rdfs:seeAlso "NCBI_Protein_ID: 119351647; PMID: 17261603" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002632 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaBA, clpP, and fliD mutant (CVD 1923) is attenuated in mice after oral immunization. This mutant is also protective, with a vaccine efficacy of 80% in mice against wild type challenge from Salmonella Typhimurium" ; rdfs:label "fliD from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1253481; PMID: 21807911" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002633 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A gal E mutant in strain Ty2 was isolated, attenuated, and protected mice against lethal challenge" ; rdfs:label "galE from Salmonella Typhi" ; rdfs:seeAlso "NCBI_Gene_ID: 1067209; PMID: 1092768" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001419, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002634 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis" ; rdfs:label "guaA from Salmonella Enteritidis" ; rdfs:seeAlso "NCBI_Gene_ID: 6948075; PMID: 21807911" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002635 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002636" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ; rdfs:label "guaA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1254032; PMID: 21807911" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002636 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002635 ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ; rdfs:label "obsolete guaA from Salmonella spp." ; rdfs:seeAlso "NCBI_Gene_ID: 1254032; PMID: 21807911" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002637 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002638" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ; rdfs:label "guaB from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1254033; PMID: 21807911" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002638 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002637 ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ; rdfs:label "obsolete guaB from Salmonella spp." ; rdfs:seeAlso "NCBI_Gene_ID: 1254033; PMID: 21807911" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002639 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002640" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica" ; rdfs:label "guaB from Salmonella Enteritidis" ; rdfs:seeAlso "NCBI_Gene_ID: 6949287; PMID: 17261603" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002640 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002639 ; a owl:Class ; rdfs:comment "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica" ; rdfs:label "obsolete guaB from Salmonella spp." ; rdfs:seeAlso "NCBI_Gene_ID: 6949287; PMID: 17261603" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002641 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ; rdfs:label "gyrA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1253794; PMID: 15542179" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002642 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Oral immunization with the Salmonella hfq deletion mutant efficiently protects mice against subsequent oral challenge with virulent strain of Salmonella Typhimurium" ; rdfs:label "hfq from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1255887; PMID: 21347426" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002643 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A htrA mutant in Salmonella typhimurium is attenuated and provides protection in mice against an oral challenge with virulent S. typhimurium SL1344" ; rdfs:label "htrA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 301156836; PMID: 1584006]" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002644 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A lon mutant, in combination with a cpxR mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ; rdfs:label "lon from Salmonella Gallinarum" ; rdfs:seeAlso "NCBI_Gene_ID: 6923289; PMID: 20487719" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001420, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002645 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An lppA mutant, in combination with an lppB/msbB mutation, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "lppA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 323129647; PMID: 17997275" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002646 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002647" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "lppB from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 267993263; PMID: 17997275" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002647 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002646 ; a owl:Class ; rdfs:comment "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "obsolete lppB from Salmonella spp." ; rdfs:seeAlso "NCBI_Protein_ID: 267993263; PMID: 17997275" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002648 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002649" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" ; rdfs:label "msbB from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 4104731; PMID: 17997275" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002649 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002648 ; a owl:Class ; rdfs:comment "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" ; rdfs:label "obsolete msbB from Salmonella spp." ; rdfs:seeAlso "NCBI_Protein_ID: 4104731; PMID: 17997275" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002650 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "In a pig infection experiment including two oral immunizations with SalmoporcDeltaompD (OmpD, nmpC) and challenge with a multiresistant S. enterica serovar Typhimurium DT104 clinical isolate, we confirmed the protective efficacy of SalmoporcDeltaompD in pigs, showing a significant reduction of both clinical symptoms and colonization of lymph nodes and intestinal tract" ; rdfs:label "nmpC from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 517159; PMID: 17296750" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002651 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A nuoG mutant is attenuated in chickens and induced significant protection from challenge with wild type S. Gallinarum" ; rdfs:label "nuoG from Salmonella Gallinarum" ; rdfs:seeAlso "NCBI_Gene_ID: 6924283; PMID: 9682335" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001420, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002652 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An ompR mutant is attenuated in mice after oral challenge. Twenty eight days after immunization, mice were challenged with wild type S. typhimurium and were significantly protected" ; rdfs:label "ompR from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 301160045; PMID: 2543631" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002653 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Three S. typhi deletion mutants (phoP, rpoS, and rpoS-phoP double mutant) were constructed and characterized with respect to invasiveness, virulence, and protective immune response compared with wild-type Ty2. All S. typhi mutants showed an increase in the specific serum IgG levels and T-cell-mediated immunity, and showed equal protection abilities against a wild-type Ty2 challenge after two rounds of immunization in BALB/c mice" ; rdfs:label "phoP from Salmonella Typhi" ; rdfs:seeAlso "NCBI_Gene_ID: 1071307; PMID: 17725620" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001419, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002654 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A poxA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ; rdfs:label "poxA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1255870; PMID: 9826331" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002655 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum" ; rdfs:label "relA from Salmonella Gallinarum" ; rdfs:seeAlso "NCBI_Gene_ID: 6922678; PMID: 21046347" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001420, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002656 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ; rdfs:label "rfc from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 267993210; PMID: 20799091" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002657 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ; rdfs:label "rpoB from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 255679; PMID: 15542179" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002658 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Immunizations with Salmonella typhimurium rpoS and rpoS aroA mutants protected susceptible BALB/c mice against subsequent oral challenge with virulent S. typhimurium. When administered orally or intraperitoneally, rpoS derivatives of the mouse-virulent S. typhimurium strains, C52 and SL1344, were highly attenuated and were efficient single-dose live vaccines" ; rdfs:label "rpoS from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 301159483; PMID: 8899717" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002659 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A ruvB mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "ruvB from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1253415; PMID: 20670908" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002660 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum" ; rdfs:label "spoT from Salmonella Gallinarum" ; rdfs:seeAlso "NCBI_Gene_ID: 6924903; PMID: 21046347" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001420, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002661 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A surA mutant (BRD1115) is attenuated in BALB/c mice and induces protection from challenge with wild type S. typhimurium" ; rdfs:label "surA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1251610; PMID: 10678914" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002662 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A tolA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "tolA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 301157338; PMID: 19118362" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002663 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A trxA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "trxA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 301160436; PMID: 19884329" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002664 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A wecA mutant (DSM645) is attenuated in C57BL/6J mice through i.p. and oral immunization. This mutant also protects against challenge with S. typhimurium strains TML and SL1344 30 days after immunization" ; rdfs:label "wecA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Protein_ID: 20140863; PMID: 22025511" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002665 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ; rdfs:label "znuA from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 253412; PMID: 21219981" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002666 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ; rdfs:label "znuB from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1253414; PMID: 21219981" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002667 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ; rdfs:label "znuC from Salmonella Typhimurium" ; rdfs:seeAlso "NCBI_Gene_ID: 1253413; PMID: 21219981" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001421, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002668 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002669", "VO:0002670", "VO:0002671" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "aroA from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 1077373; PMID: 7927802" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000169, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002669 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002668 ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "obsolete aroA from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 1077373; PMID: 7927802" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002670 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002668 ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "obsolete aroA from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 1077373; PMID: 7927802" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002671 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002668 ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "obsolete aroA from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 1077373; PMID: 7927802" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002672 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002673" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri" ; rdfs:label "aroD from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 1078189; PMID: 8356844" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000169, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002673 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002672 ; a owl:Class ; rdfs:comment "An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri" ; rdfs:label "obsolete aroD from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 1078189; PMID: 8356844" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002674 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An envZ mutant (SC433) is greatly decreased in virulence in macaque monkeys, though some mild clinical signs were still recorded. This mutant is also highly protective against a challenge of wild type S. flexneri delivered 1 month after inoculation" ; rdfs:label "envZ from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 4207729; PMID: 1887672" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000169, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002675 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002676" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "icsA/virG from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 1238021; PMID: 7927802" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000169, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002676 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002675 ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "obsolete icsA/virG from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 1238021; PMID: 7927802" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002677 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A virG, senA, senB, and msbB2 mutant (WRSs3) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs3 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "msbB2 from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 3670926; PMID: 19932216]" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000169, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002678 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002679" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "senA from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 3671021; PMID: 19932216" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000169, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002679 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002678 ; a owl:Class ; rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "obsolete senA from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 3671021; PMID: 19932216" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002680 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002681" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "senB from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 3668265; PMID: 19932216" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000169, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002681 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002680 ; a owl:Class ; rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "obsolete senB from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 3668265; PMID: 19932216" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002682 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002683" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei" ; rdfs:label "virG from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 3670887; PMID: 9712824" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000169, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002683 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002682 ; a owl:Class ; rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei" ; rdfs:label "obsolete virG from Shigella" ; rdfs:seeAlso "NCBI_Gene_ID: 3670887; PMID: 9712824" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002684 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A hemA mutant is highly attenuated in mice and rabbits and induces protection from challenge with wild type V. cholerae in rabbits" ; rdfs:label "hemA from Vibrio cholerae" ; rdfs:seeAlso "NCBI_Protein_ID: 12656010; PMID: 16102875" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001423, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002685 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in mice, and after 3 doses induces significant protection from challenge with wild type Y. enterocolitica" ; rdfs:label "aroA from Yersinia enterocolitica" ; rdfs:seeAlso "NCBI_Gene_ID: 4713234; PMID: 2777382" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002686 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A htrA mutant in Yersinia enterocolitica was attenuated and provided partial protection against challenge in mice" ; rdfs:label "htrA from Yersinia enterocolitica" ; rdfs:seeAlso "NCBI_Gene_ID: 4715899; PMID: 8675311" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002687 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A ompR mutant in Yersinia enterocolitica was attenuated and provided a partial protection from challenge in mice" ; rdfs:label "ompR from Yersinia enterocolitica" ; rdfs:seeAlso "NCBI_Gene_ID: 4716266; PMID: 9711851" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002688 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A sodA mutant in Yersinia enterocolitica was highly attenuated and mice immunized with a single oral dose of the mutant strain were protected against a lethal oral-challenge infection with wild-type Y. enterocolitica" ; rdfs:label "sodA from Yersinia enterocolitica" ; rdfs:seeAlso "NCBI_Gene_ID: 4716532; PMID: 10496939" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002689 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "guaA from Yersinia pestis" ; rdfs:seeAlso "NCBI_Gene_ID: 1146310; PMID: 0096773" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002690 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "guaB from Yersinia pestis" ; rdfs:seeAlso "NCBI_Gene_ID: 1146309; PMID: 0096773" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002691 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An IpxM mutant is attenuated in mice and guinea pigs. This mutant also conferred modest protection from challenge with wild type Y. pestis in Balb/c mice and significant protection in guinea pigs and outbred mice" ; rdfs:label "ipxM from Yersinia pestis" ; rdfs:seeAlso "NCBI_Gene_ID: 1174901; PMID: 17913308" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002692 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An nlpD mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "nlpD from Yersinia pestis" ; rdfs:seeAlso "NCBI_Protein_ID: 224483371; PMID: 19759820" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002693 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A pcm mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "pcm from Yersinia pestis" ; rdfs:seeAlso "NCBI_Protein_ID: 224483370; PMID: 14742535" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002694 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis" ; rdfs:label "smpB from Yersinia pestis" ; rdfs:seeAlso "NCBI_Gene_ID: 1173949; PMID: 20065026" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002695 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis" ; rdfs:label "ssrA from Yersinia pestis" ; rdfs:seeAlso "NCBI_Gene_ID: 1173948; PMID: 20065026" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002696 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A yopH mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "yopH from Yersinia pestis" ; rdfs:seeAlso "NCBI_Gene_ID: 1172712; PMID: 17652523" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002697 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A phoP mutant in Yersinia pseudotuberculosis (Yptb) was attenuated and provided protection against oral challenge with virulent Yptb in mice" ; rdfs:label "phoP from Yersinia pseudotuberculosis" ; rdfs:seeAlso "NCBI_Gene_ID: 2956268; PMID: 17194509" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002698 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in rainbow trout and induces significant protection from challenge with wild type Y. ruckeri" ; rdfs:label "aroA from Yersinia ruckeri" ; rdfs:seeAlso "NCBI_Protein_ID: 15420539; PMID: 16083447" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002699 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A thymidine kinase-deficient mutant (B8-D53) showed no detectable thymidine kinase-inducing activity and was attenuated in calves. B8-D53 also induced protection from challenge with wild type BHV-1" ; rdfs:label "UL23 from Bovine herpesvirus 1" ; rdfs:seeAlso "NCBI_Gene_ID: 1487380; PMID: 2994602" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001424, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002700 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A deletion of BHV-1 gE gene in strain A is considered as a live attenuated vaccine. After challenge, vaccinated calves were protected against disease and virus shedding was reduced" ; rdfs:label "US8 from Bovine herpesvirus 1" ; rdfs:seeAlso "NCBI_Gene_ID: 1487407; PMID: 8023552" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001424, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002701 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A glycoprotein G deletion in bovine respiratory syncytial virus(rBRSV) and recombinant rBRSV was attenuated and provided protection against a BRSV challenge infection in calves" ; rdfs:label "glycoprotein G from Bovine Respiratory Syncytial Virus" ; rdfs:seeAlso "NCBI_Gene_ID: 1489813; PMID: 12414977" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001429, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002702 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An N269A/Q mutation in the E(rns) protein created an attenuated mutant in swine. This mutant was able to induce effective protection in swine against challenge with wild type CSFV" ; rdfs:label "E(rns) from Classical swine fever virus" ; rdfs:seeAlso "NCBI_Protein_ID: 130457; PMID: 17904607" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002703 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An N to A amino acid substitution was made in the N594 site of the E1 glycoprotein, resulting in attenuation of the virus in swine. This attenuated virus induced protection against challenge with wild type CSFV" ; rdfs:label "E1 from Classical swine fever virus" ; rdfs:seeAlso "NCBI_Protein_ID: 325461; PMID: 19203774" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002704 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A E2 mutant in Classical swine fever virus is attenuated and provides protection in pigs after oronasal vaccination (not intradermal vaccination) against lethal challenge dose of CSFV strain Eystrup" ; rdfs:label "E2 gene from Classical swine fever virus" ; rdfs:seeAlso "NCBI_Gene_ID: 920146; PMID: 15837238" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002705 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A glycoprotein E mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice" ; rdfs:label "gE from Equid herpesvirus" ; rdfs:seeAlso "NCBI_Protein_ID: 330789; PMID: 17085880" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001431, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002706 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A glycoprotein I mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice" ; rdfs:label "gI from Equid herpesvirus" ; rdfs:seeAlso "NCBI_Protein_ID: 330788; PMID: 17085880" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001431, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002707 obo:IAO_0000115 "A thymidine kinase-deficient mutant (PR1) is attenuated in mice and induced significant protection from challenge with wild type EHV-1 5 weeks after vaccination. In foals, PR1 also showed attenuation; however, the mutant induced only partial protection from challenge with EHV-1" ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "TK from Equid herpesvirus" ; rdfs:seeAlso "NCBI_Protein_ID: 59214; PMID: 16930871" ; rdfs:subClassOf obo:OBI_0000011 . obo:VO_0002708 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A thymidine kinase-deficient mutant (C7301dlTK) is attenuated in cats and induced significant protection from wild type FHV-1 4 weeks after vaccination" ; rdfs:label "UL23 from Feline herpesvirus 1" ; rdfs:seeAlso "NCBI_Gene_ID: 8658565; PMID: 8645090" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001432, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002709 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Feline immunodeficiency virus (FIV) made defective in the accessory gene ORF-A were previously shown to be greatly attenuated in its ability to replicate in lymphocytes but to grow normally or near normally in other cell types. 3/9 vaccinees (cats) showed no evidence of the challenge virus over a 15-month observation period. In the other vaccinees, the challenge virus was predominant for various periods of time, but pre-existing viral loads and CD4 lymphocyte counts were either unaffected or altered only marginally and transiently" ; rdfs:label "ORF-A from Feline immunodeficiency virus" ; rdfs:seeAlso "NCBI_Gene_ID: 1724707; PMID: 15680433" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001433, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002710 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A vif mutant in feline immunodeficiency virus was attenuated and FIV-pPPRŒîvif proviral DNA protected cats against challenge with the homologous FIV-PPR biological isolate." ; rdfs:label "vif from Feline immunodeficiency virus" ; rdfs:seeAlso "NCBI_Gene_ID: 1724709; PMID: 10891409" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001433, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002711 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "3a from Feline infectious peritonitis virus" ; rdfs:seeAlso "NCBI_Gene_ID: 10040181; PMID: 15047802" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001434, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002712 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "3b from Feline infectious peritonitis virus" ; rdfs:seeAlso "NCBI_Gene_ID: 10040182; PMID: 15047802" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001434, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002713 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "3c from Feline infectious peritonitis virus" ; rdfs:seeAlso "NCBI_Gene_ID: 10040183; PMID: 15047802" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001434, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002714 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "7a from Feline infectious peritonitis virus" ; rdfs:seeAlso "NCBI_Gene_ID: 10040187; PMID: 15047802" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001434, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002715 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "7b from Feline infectious peritonitis virus" ; rdfs:seeAlso "NCBI_Gene_ID: 10040188; PMID: 15047802" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001434, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002716 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A UL0 mutant in infectious laryngotracheitis virus (ILTV) was attenuated. Chickens immunized with UL0-negative ILTV were protected from clinical disease after subsequent infection with virulent ILTV" ; rdfs:label "UL0 from Gallid herpesvirus 1" ; rdfs:seeAlso "NCBI_Gene_ID: 3239037; PMID: 14645915" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001435, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002717 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A thymidine-kinase mutant is attenuated in chickens and induced protection from challenge with wild type GHV-1" ; rdfs:label "UL23 from Gallid herpesvirus 1" ; rdfs:seeAlso "NCBI_Gene_ID: 3239035; PMID: 12021870" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001435, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002718 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A UL47 mutant in avian infectious laryngotracheitis virus is attenuated and provides protection in chicken against subsequent challenge infection with virulent ILTV" ; rdfs:label "UL47 from Gallid herpesvirus 1" ; rdfs:seeAlso "NCBI_Gene_ID: 3239064; PMID: 17325345" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001435, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002719 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Researchers generated a series of woodchuck hepatitis virus (WHV) X mutants. Woodchucks inoculated with X mutants, including those with no serologic evidence of infection, were protected from later challenge with infectious Woodchuck Hepatitis Virus, suggesting previous infection with resulting protective immunity" ; rdfs:label "HBVgp3 X protein from Hepatitis B virus" ; rdfs:seeAlso "NCBI_Gene_ID: 944566; PMID: 11714744" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001436, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002720 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "KOS-gDA3C is attenuated with mutations in gD gene in causing skin lesions at the inoculation and zosteriform sites, yet it is as effective as rKOS-gDA3C in protecting mice against HSV-1 challenge" ; rdfs:label "gD from Herpes simplex virus type 1 and 2" ; rdfs:seeAlso "NCBI_Protein_ID: 19548971; PMID: 18243431" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001437, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002721 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A gH mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1" ; rdfs:label "gH from Herpes simplex virus type 1 and 2" ; rdfs:seeAlso "NCBI_Protein_ID: 138315; PMID: 8289395" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001437, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002722 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A live-attenuated HSV-2 ICP0 virus provides significant protection against wild-type HSV-2 (MS strain) challenge in mice" ; rdfs:label "iCP0 from Herpes simplex virus type 1 and 2" ; rdfs:seeAlso "NCBI_Gene_ID: 1487289; PMID: 21412438" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001454, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002723 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A thymidine kinase-deficient (TK) mutant was found to be attenuated in mice. This mutant induced complete protection from challenge with wild type HSV" ; rdfs:label "TK from Herpes simplex virus type 1 and 2" ; rdfs:seeAlso "NCBI_Gene_ID: 2703374; PMID: 212476" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001437, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002724 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A UL29 mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1" ; rdfs:label "UL29 from Herpes simplex virus type 1 and 2" ; rdfs:seeAlso "NCBI_Gene_ID: 2703458; PMID: 8289372" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001437, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002725 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from <10% of vaccinated mice compared with 100% of mock-vaccinated mice" ; rdfs:label "US8 from Herpes simplex virus type 1 and 2" ; rdfs:seeAlso "NCBI_Gene_ID: 2703448; PMID: 18562543" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001437, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002726 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A G mutant is attenuated in African green monkeys and induces protection from challenge with wild type HMPV" ; rdfs:label "G protein from Human metapneumovirus" ; rdfs:seeAlso "NCBI_Protein_ID: 75549950; PMID: 16160190" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001438, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002727 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An M2-2 mutant is attenuated in African green monkeys and induced protection from challenge with wild type HMPV" ; rdfs:label "M2-2 from Human metapneumovirus" ; rdfs:seeAlso "NCBI_Protein_ID: 75549952; PMID: 16160190" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001438, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002728 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An M2-2 mutant of human respiratory syncytial virus A2 is attenuated in African green monkeys. When challenged with wild type RSV, two doses provided complete protection against challenge in the lower respiratory tract and a significant reduction of the challenge virus in the upper respiratory tract" ; rdfs:label "M2-2 from Human Respiratory Syncytial Virus" ; rdfs:seeAlso "NCBI_Protein_ID: 81925031; PMID: 12922094" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001439, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002729 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A mutation in the non-virion protein of IHNV causes attenuated growth in rainbow trout and is able to provide significant protection from subsequent challenge with wild type IHNV" ; rdfs:label "NV from Infectious Hematopoietic Necrosis Virus" ; rdfs:seeAlso "NCBI_Gene_ID: 1489849; PMID: 15047826" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001440, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002730 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Mutant influenza virus that lacks the transmembrane and cytoplasmic tail domains of M2 (M2 knockout [M2KO]) from Influenza A virus (A/Puerto Rico/8/34(H1N1)) is attenuated in both cell culture and mice. Mice intranasally vaccinated with M2KO virus developed protective immune responses and survived a lethal challenge with the wild-type virus, suggesting that the M2KO virus has potential as a live attenuated vaccine" ; rdfs:label "M2 from Influenza virus" ; rdfs:seeAlso "NCBI_Gene_ID: 956528; PMID: 19321619" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000185, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002731 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Intranasal inoculation of mice, pigs, horses, and macaques with NS1-modified influenza virus strains induced robust humoral and cellular immune responses, and generated immune protection against challenge with wild-type virus" ; rdfs:label "NS1 from Influenza virus" ; rdfs:seeAlso "NCBI_Protein_ID: 505039; PMID: 19768406" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000185, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002732 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A mutation in the GP5 protein attenuates HP-PRRSV in piglets. This mutant (HuN4-F112) induces protection against challenge with wild type HP-PRRSV" ; rdfs:label "GP5 protein from Porcine respiratory and reproductive syndrome virus" ; rdfs:seeAlso "NCBI_Protein_ID: 149389584; PMID: 19339125" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001441, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002733 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A glycoprotein E mutant, in combination with UL23 and glycoprotein G mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ; rdfs:label "glycoprotein E from Pseudorabies virus" ; rdfs:seeAlso "NCBI_Protein_ID: 307634504; PMID: 12488067" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002734 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ; rdfs:label "glycoprotein G from Pseudorabies virus" ; rdfs:seeAlso "NCBI_Protein_ID: 15422177; PMID: 12488067" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002735 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A glycoprotein M, gM, deletion in pseudorabies virus was attenuated and induced protection in piglets against intranasal challenge with 108 p.f.u. of the highly virulent PrV strain NIA-3" ; rdfs:label "glycoprotein M from Pseudorabies virus" ; rdfs:seeAlso "NCBI_Protein_ID: 1478255; PMID: 9292000" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002736 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky's disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3" ; rdfs:label "gp50 from Pseudorabies virus" ; rdfs:seeAlso "NCBI_Gene_ID: 2952548; PMID: 8178562" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002737 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky's disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3" ; rdfs:label "gp63 from Pseudorabies virus" ; rdfs:seeAlso "NCBI_Gene_ID: 2952540; PMID: 8178562" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002738 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ; rdfs:label "UL23 from Pseudorabies virus" ; rdfs:seeAlso "NCBI_Gene_ID: 2952559; PMID: 12488067" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002739 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A UL50 mutant is attenuated in pseudorabies virus and induces significant protection in pigs from challenge with the highly virulent NIA-3 strain of PrV" ; rdfs:label "UL50 from Pseudorabies virus" ; rdfs:seeAlso "NCBI_Gene_ID: 2952537; PMID: 9228681" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002740 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Researchers intranasally inoculated pigs, the natural host of this virus, with mutant PRV strains in which the genes encoding the protein kinase (US3) proteins were inactivated. After challenge infection with the virulent PRV strain NIA-3, no virus was excreted by wt PRV- and PK- mutant-immunized animals, indicating complete protective immunity" ; rdfs:label "US3 from Pseudorabies virus" ; rdfs:seeAlso "NCBI_Gene_ID: 2952561; PMID: 7975253" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001442, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002741 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A glycoprotein G mutant in rabies virus is attenuated. After a one-dose intramuscular vaccination, the ERAg3m virus protected 100% of mice and hamsters from lethal challenge. In co-infections, using a lethal dose of street rabies virus mixed with ERAg3m, 100% of hamsters and 90% of mice survived and were protected against subsequent infection" ; rdfs:label "glycoprotein G from Rabies virus" ; rdfs:seeAlso "NCBI_Gene_ID: 1489856; PMID: 21514343" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001443, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002742 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A P gene mutant is attenuated in mice and induces significant protection from challenge with wild type Rabies virus" ; rdfs:label "P protein from Rabies virus" ; rdfs:seeAlso "NCBI_Protein_ID: 291220682; PMID: 15896403" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001443, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002743 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An E mutant is attenuated in hamsters and induces significant protection from challenge with wild type SARS" ; rdfs:label "E from SARS-CoV" ; rdfs:seeAlso "NCBI_Gene_ID: 1489671; PMID: 18463152" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001444, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002744 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A SIV nef mutant is attenuated in rhesus monkeys and induces protection from challenge with wild type SIV" ; rdfs:label "nef from Simian Immunodeficiency Virus" ; rdfs:seeAlso "NCBI_Gene_ID: 1490008; PMID: 1470917" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001445, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002745 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A virus with a mutation in protein C is attenuated in mice and induced protection from challenge with wild type TBE virus" ; rdfs:label "C protein from Tick-borne Encephalitis Virus" ; rdfs:seeAlso "NCBI_Protein_ID: 206570298; PMID: 11884577" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001446, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002746 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE" ; rdfs:label "E1 glycoprotein from VEE Virus" ; rdfs:seeAlso "NCBI_Protein_ID: 798795; PMID: 7676619" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001447, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002747 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE" ; rdfs:label "PE2 from VEE Virus" ; rdfs:seeAlso "NCBI_Protein_ID: 229558446; PMID: 7676619" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001447, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002748 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A virus with a C protein mutation is attenuated in mice and induces significant protection from challenge with wild type West Nile virus" ; rdfs:label "C protein from West Nile virus" ; rdfs:seeAlso "NCBI_Protein_ID: 158516889; PMID: 20600500" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001448, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002749 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002750" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ; rdfs:label "E1 from Western equine encephalomyelitis virus" ; rdfs:seeAlso "NCBI_Protein_ID: 17148717; PMID: 12641414" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001449, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002750 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002749 ; a owl:Class ; rdfs:comment "A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ; rdfs:label "obsolete E1 from Western equine encephalomyelitis virus" ; rdfs:seeAlso "NCBI_Protein_ID: 17148717; PMID: 12641414" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002751 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002752" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ; rdfs:label "E2 gene from Western equine encephalomyelitis virus" ; rdfs:seeAlso "NCBI_Protein_ID: 29611992; PMID: 12641414" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001449, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002752 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002751 ; a owl:Class ; rdfs:comment "A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ; rdfs:label "obsolete E2 from Western equine encephalomyelitis virus" ; rdfs:seeAlso "NCBI_Protein_ID: 29611992; PMID: 12641414" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002753 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002754" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur" ; rdfs:label "PE2 from Western equine encephalomyelitis virus" ; rdfs:seeAlso "NCBI_Protein_ID: 90811336; PMID: 12641414" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001449, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002754 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002753 ; a owl:Class ; rdfs:comment "A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur" ; rdfs:label "obsolete PE2 from Western equine encephalomyelitis virus" ; rdfs:seeAlso "NCBI_Protein_ID: 90811336; PMID: 12641414" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002755 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A cen1 mutant is attenuated in mice and hamsters and induces significant protection from challenge with wild type L. donovani" ; rdfs:label "cen1 from Leishmania donovani" ; rdfs:seeAlso "NCBI_Protein_ID: 15488542; PMID: 19592661" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001450, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002756 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A Leishmania infantum deletion mutant of HSP70-II gene is attenuated and provides protection against Leishmania infection in the L. major-BALB/c infection model. Also, DeltaHSP70-II is a safe live vaccine as immunodeficient SCID mice, and hamsters, infected with mutant parasites did not develp any sign of pathology" ; rdfs:label "HSP70 II from Leishmania infantum" ; rdfs:seeAlso "NCBI_Gene_ID: 5073319; PMID: 21794145" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0002515, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002757 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A genetically attenuated parasite (GAP) with a mutation in the FabB/FabF gene is attenuated in mice by arresting in the late liver stage. It also conferred complete protection in mice from challenge with wild type Plasmodium" ; rdfs:label "fabB/fabF from Plasmodium falciparum" ; rdfs:seeAlso "NCBI_Gene_ID: 3885996; PMID: 21669394" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0000172, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002758 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Genetically attenuated P36p-deficient Plasmodium berghei sporozoites provide protection against sporozoites challenge in mice" ; rdfs:label "p36p from Plasmodium berghei" ; rdfs:seeAlso "NCBI_Gene_ID: 3424772; PMID: 7604034" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001451, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002759 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites" ; rdfs:label "py36 from Plasmodium yoelii" ; rdfs:seeAlso "NCBI_Protein_ID: 23479924; PMID: 17517871" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001452, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002760 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites" ; rdfs:label "py52 from Plasmodium yoelii" ; rdfs:seeAlso "NCBI_Protein_ID: 15193062; PMID: 17517871" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001452, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002761 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "Deletion of UIS3 in Plasmodium yoelii provided attenuation and full protection in mice by Pyuis3(-) sporozoites required at least 2 immunizations against challenges with infectious sporozoites" ; rdfs:label "UIS3 from Plasmodium yoelii" ; rdfs:seeAlso "NCBI_Gene_ID: 3830198; PMID: 17624848" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001452, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002762 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A mic2 mutant is attenuated in mice and induces protection from challenge with wild type T. gondii" ; rdfs:label "mic2 from Toxoplasma gondii" ; rdfs:seeAlso "NCBI_Protein_ID: 1923217; PMID: 16933991" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001453, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002763 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002764" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii" ; rdfs:label "OMPDC from Toxoplasma gondii" ; rdfs:seeAlso "NCBI_Gene_ID: 7899615; PMID: 20605980" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001453, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002764 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002763 ; a owl:Class ; rdfs:comment "An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii" ; rdfs:label "obsolete OMPDC from Toxoplasma gondii" ; rdfs:seeAlso "NCBI_Gene_ID: 7899615; PMID: 20605980" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002765 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "gene" ; a owl:Class ; rdfs:comment "A UP mutant, in combination with an OMPDC mutation, is attenuated in mice and induces significant protection from wild type T. gondii" ; rdfs:label "UP from Toxoplasma gondii" ; rdfs:seeAlso "NCBI_Gene_ID: 900273; PMID: 20605980" ; rdfs:subClassOf obo:VO_0000048, obo:VO_0001453, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0001361 ] . obo:VO_0002766 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "The mutant strain, with deletion of apxIA gene, obtained in this study offered a level of cross-serovar protection against A. pleuropneumoniae infection in mice and pigs (Reference: PMID: 16930871)." ; rdfs:label "Actinobacillus pleuropneumoniae apxIA mutant vaccine" ; rdfs:subClassOf obo:VO_0001130 . obo:VO_0002767 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "In the intra-peritoneal mouse model, the virulence of the mutant strain decreased at least 100 fold compared with the parent strain. The mutant was evaluated as a potential vaccine using a vaccination-challenge trial. The death number and lung lesion score in the vaccinated pigs given the serovar 1 challenge were obviously lower than those in the unvaccinated pigs" ; rdfs:label "Actinobacillus pleuropneumoniae ApxIC mutant vaccine" ; rdfs:subClassOf obo:VO_0001130 . obo:VO_0002768 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002774" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Deletion in ureC and apxIIA genes of Actinobacillus pleuropneumoniae serotype 2 prototype provides attenuation and protection in pigs against challenge with the virulent parent strain of A. pleuropneumoniae", "Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application" ; rdfs:label "Actinobacillus pleuropneumoniae ureC and apxIIA double mutant deletion vaccine" ; rdfs:subClassOf obo:VO_0001130 . obo:VO_0002769 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002773" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae was constructed based on HB04C(-) by transconjugation and counterselection. The results demonstrated that the DeltaapxIICDeltaapxIVA double mutant strain was less virulent than HB04C(-). Despite attenuation of virulence, the DeltaapxIICDeltaapxIVA double mutant remains immunogenic and conferred a similar level of protective immunity to pigs against challenge with a lethal dose of a heterologous fully virulent standard serovar 1 strain of A. pleuropneumoniae. (Reference: PubMed: 17767980)", "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" ; rdfs:label "Actinobacillus pleuropneumoniae apxIIC and apxIVA double deletion mutant vaccine" ; rdfs:subClassOf obo:VO_0001130 . obo:VO_0002770 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0011385 ; a owl:Class ; rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" ; rdfs:label "obsolete A. pleuropneumoniae HS93C-Ampr" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002771 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002772" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An apxIIIB mutant, in combination with an apxIIID mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain", "An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain" ; rdfs:label "Actinobacillus pleuropneumoniae apxIIIB and apxIIID double mutant vaccine" ; rdfs:subClassOf obo:VO_0001130 . obo:VO_0002772 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002771 ; a owl:Class ; rdfs:comment "An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain" ; rdfs:label "obsolete Actinobacillus pleuropneumoniae apxIIIB and apxIIID double mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002773 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002769 ; a owl:Class ; rdfs:comment "A precisely defined DeltaapxIICDeltaapxIVA double-deletion mutant of A. pleuropneumoniae was constructed based on HB04C(-) by transconjugation and counterselection. The results demonstrated that the DeltaapxIICDeltaapxIVA double mutant strain was less virulent than HB04C(-). Despite attenuation of virulence, the DeltaapxIICDeltaapxIVA double mutant remains immunogenic and conferred a similar level of protective immunity to pigs against challenge with a lethal dose of a heterologous fully virulent standard serovar 1 strain of A. pleuropneumoniae. (Reference: PubMed: 17767980)" ; rdfs:label "obsolete Actinobacillus pleuropneumoniae apxIIC and apxIVA double deletion mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002774 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002768 ; a owl:Class ; rdfs:comment "Deletions were introduced into the ureC and apxIIA genes of an Actinobacillus pleuropneumoniae serotype 2 strain by homologous recombination and counterselection. The double-mutant contains no foreign DNA, is highly attenuated, protects pigs from homologous challenge upon a single aerosol application" ; rdfs:label "obsolete Actinobacillus pleuropneumoniae ureC and apxIIA double mutant deletion vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002775 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An mntA deletion mutant, generated by allelic replacement, in Bacillus anthracis was attenuated and provided protection for guinea pigs against lethal spore dose (60 LD50) of the virulent B. anthracis Vollum strain" ; rdfs:label "Bacillus anthracis mntA deletion mutant vaccine" ; rdfs:subClassOf obo:VO_0000013 . obo:VO_0002776 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes" ; rdfs:label "Listeria monocytogenes actA mutant vaccine" ; rdfs:subClassOf obo:VO_0002500 . obo:VO_0002777 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002778" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A plcB mutant, in combination with an actA mutant, is attenuated in mice and induces significant protection from challenge with wild type L. monocytogenes", "An actA mutant is attenuated in mice and induced significant protection from challenge with wild type L. monocytogenes" ; rdfs:label "Listeria monocytogenes actA/plcB mutant vaccine" ; rdfs:subClassOf obo:VO_0002500 . obo:VO_0002778 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002777 ; a owl:Class ; rdfs:comment "A plcB mutant, in combination with an actA mutant, is attenuated in mice and induces significant protection from challenge with wild type L. monocytogenes" ; rdfs:label "obsolete Listeria monocytogenes actA/plcB mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002779 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A M. avium relA mutant is attenuated in calves and goats. This mutant also elicited an immune response in goats that limited colonization by challenge wild type M. avium" ; rdfs:label "Mycobacterium avium relA mutant vaccine" ; rdfs:subClassOf obo:VO_0002501 . obo:VO_0002780 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A drrC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "Mycobacterium tuberculosis drrC mutant vaccine" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_1773 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:OGG_3000888491 ] ) ] ] . obo:VO_0002781 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An fadD26 mutant is attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "Mycobacterium tuberculosis fadD26 mutant vaccine" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_1773 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:OGG_3000887603 ] ) ] ] . obo:VO_0002782 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Deletion of leuD gene was shown to be highly attenuated. Immunocompetent BALB/c mice vaccinated with the DleuD auxotroph were protected as well as BCG in terms of survival following an intravenous or aerosol challenge with virulent M. tuberculosis" ; rdfs:label "Mycobacterium tuberculosis leuD mutant vaccine" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_1773 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:OGG_3000888225 ] ) ] ] . obo:VO_0002783 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A lysA mutant, in combination with a secA2 mutation, is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "Mycobacterium tuberculosis lysA/secA2 mutant vaccine" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_1773 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OGG_3000885594 obo:OGG_3000886960 ) ] ] ) ] ] . obo:VO_0002784 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A Mce-2 mutant in Mycobacterium tuberculosis is attenuated and provides protection against challenge for mice" ; rdfs:label "Mycobacterium tuberculosis mce-2/mce-3 mutant vaccine" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0002785 obo:IAO_0000115 "A viral vaccine that protects against infection with Chikungunya virus" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "chikungunya virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_37124 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_37124 ] . obo:VO_0002786 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "Mycobacterium tuberculosis panCD mutant vaccine" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_1773 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OGG_3000885459 obo:OGG_3000885596 ) ] ] ) ] ] . obo:VO_0002787 obo:IAO_0000115 "RD1 and panCD mutants in Mycobacterium tuberculosis were attenuated and provided protection in CD4-deficient mice against an aerosol challenge with virulent M. tuberculosis" ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A panCD mutant is attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis" ; rdfs:label "Mycobacterium tuberculosis RD1/panCD mutant vaccine" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0002788 obo:IAO_0000115 "a bacterial vaccine against Streptococcus suis infection" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus suis vaccine" ; rdfs:subClassOf obo:VO_0000772, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1307 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1307 ] . obo:VO_0002789 obo:IAO_0000115 "a diphtheria vaccine against infection with Corynebacterium pseudotuberculosis" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Corynebacterium pseudotuberculosis vaccine" ; rdfs:subClassOf obo:VO_0000735, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1719 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1719 ] . obo:VO_0002790 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000588 ; a owl:Class ; rdfs:comment "Study evaluated immunogenicity and protection against Mycobacterium tuberculosis in rhesus monkeys with an attenuated M. tuberculosis with a disrupted phoP gene (SO2) as a single-dose vaccine. SO2 treatment showed reduced average lung bacterial counts (1.0 and 1.2 log respectively, compared with 0.4 log for BCG) and significant protective effect by reduction in C-reactive protein levels, body weight loss, and decrease of erythrocyte-associated hematologic parameters (MCV, MCH, Hb, Ht) as markers of inflammatory infection, all relative to non-vaccinated controls" ; rdfs:label "obsolete M. tuberculosis phoP mutant SO2" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002791 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A proC mutant is highly attenuated in mice and induces significant protection from challenge with wild type M. tuberculosis that is equal to the protection induced by the current vaccine BCG" ; rdfs:label "Mycobacterium tuberculosis proC mutant vaccine" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0002792 obo:IAO_0000115 "A protozoan vaccine against Trichinella spiralis infection" ; obo:IAO_0000117 "YH, RS, NF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trichinella spiralis vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5867 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5867 ] . obo:VO_0002793 obo:IAO_0000115 "A vaccine that prevents or treats atherosclerosis disease." ; obo:IAO_0000117 "YH, RS" ; obo:IAO_0000119 "http://www.onlinejacc.org/content/64/25/2779" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "atherosclerosis vaccine" ; rdfs:subClassOf obo:VO_0002813 . obo:VO_0002794 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000564 ; a owl:Class ; rdfs:comment "Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Gu√©rin vaccination" ; rdfs:label "obsolete M. tuberculosis secA2 mutant" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002795 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A sigE mutant is highly attenuated in mice and induced significant protection from challenge with wild type M. tuberculosis, more so than the existing vaccine BCG" ; rdfs:label "Mycobacterium tuberculosis sigE mutant vaccine" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_1773 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:OGG_3000888751 ] ) ] ] . obo:VO_0002796 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A trpD mutant is highly attenuated in mice and induces more protection from challenge with wild type M. tuberculosis than that induced by the current vaccine BCG" ; rdfs:label "Mycobacterium tuberculosis trpD mutant vaccine" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_1773 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:OGG_3000887681 ] ) ] ] . obo:VO_0002797 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. aureus" ; rdfs:label "Staphylococcus aureus aroA mutant vaccine" ; rdfs:subClassOf obo:VO_0002502 . obo:VO_0002798 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A vicK mutant is attenuated in mice and induced protection from challenge with wild type S. equi" ; rdfs:label "Streptococcus equi vicK mutant vaccine" ; rdfs:subClassOf obo:VO_0000948 . obo:VO_0002799 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An A. hydrophila aroA mutant is highly attenuated in trout, and a single immunization conferred significant protection from challenge with wild type A. hydrophila" ; rdfs:label "Aeromonas hydrophila aroA mutant vaccine" ; rdfs:subClassOf obo:VO_0002505 . obo:VO_0002800 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0011386 ; a owl:Class ; rdfs:comment "The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice" ; rdfs:label "obsolete A. salmonicida live-attenuated vaccine encoding AroA" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002801 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract" ; rdfs:label "Bordetella bronchiseptica aroA mutant vaccine (strain BBS18)" ; rdfs:subClassOf obo:VO_0000394 . obo:VO_0002802 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002806" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A trpE mutant, in combination with an aroA mutation, is attenuated in mice and induces significant protection from challenge with wild type B. bronchiseptica", "Inactivation of the aroA gene highly attenuates B. bronchiseptica, severely impairing its ability to colonize and survive in the respiratory tract of mice. Upon challenge with wild type B. bronchiseptica, the mice immunised with live attenuated B. bronchiseptica aroA mutant had rapidly reduced numbers of B. bronchiseptica in their respiratory tract" ; rdfs:label "Bordetella bronchiseptica aroA/trpE mutant vaccine" ; rdfs:subClassOf obo:VO_0000394 . obo:VO_0002803 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002804" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 √ó 105 CFU of RB50, the B. Bronchiseptica parent strain" ; rdfs:label "Bordetella bronchiseptica bscN and cyaA double mutant vaccine" ; rdfs:subClassOf obo:VO_0000394 . obo:VO_0002804 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002803 ; a owl:Class ; rdfs:comment "A double mutant strain of Bordetella Bronchiseptica lacking adenylate cyclase(cyaA gene) and type III secretion(bscN gene) is attenuated and provides protection in mice against 5 √ó 105 CFU of RB50, the B. Bronchiseptica parent strain" ; rdfs:label "obsolete Bordetella bronchiseptica bscN and cyaA double mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002805 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A dnt mutant in Bordetella bronchiseptica was attenuated and provides protection in guinea pigs against intranasal challenge with strain L3" ; rdfs:label "Bordetella bronchiseptica dnt mutant vaccine" ; rdfs:subClassOf obo:VO_0000394 . obo:VO_0002806 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002802 ; a owl:Class ; rdfs:comment "A trpE mutant, in combination with an aroA mutation, is attenuated in mice and induces significant protection from challenge with wild type B. bronchiseptica" ; rdfs:label "obsolete Bordetella bronchiseptica aroA/trpE mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002807 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in mice and induces significant protection from challenge with wild type B. pertussis" ; rdfs:label "Bordetella pertussis aroA mutant vaccine" ; rdfs:subClassOf obo:VO_0000765 . obo:VO_0002808 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A live attenuated B. pertussis vaccine strain BPZE1, developed by deleting dnt gene, protects mice upon a single intranasal administration" ; rdfs:label "Bordetella pertussis dnt mutant vaccine" ; rdfs:subClassOf obo:VO_0000765 . obo:VO_0002809 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A flagella-less mutant of Borrelia burgdorferi (HB19Fla-) was attenuated in immunodeficient SCID mice. Mice were challenged 28 days later with virulent strain Sh. 2 and were protected from challenge" ; rdfs:label "Borrelia burgdorferi fla mutant vaccine" ; rdfs:subClassOf obo:VO_0000764 . obo:VO_0002810 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002814", "VO:0002822" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A asp24 mutation in Brucella abortus is attenuated and provides significant protection in mice", "A virB2 mutant is attenuated in Brucella melitensis and provides protection in mice", "Mutants manB and manA were attenuated in Brucella melitensis and provided protection against challenge in mice's livers", "Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice" ; rdfs:label "B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA" ; rdfs:subClassOf obo:VO_0001134, obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29459 ] . obo:VO_0002811 obo:IAO_0000115 "A vaccine that prevents or treats diabetes." ; obo:IAO_0000117 "YH, RS" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/12956615" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diabetes vaccine" ; rdfs:subClassOf obo:VO_0002813 . obo:VO_0002812 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Brucella DeltaexsA mutant showed decreased survival in mice compared to the survival of parental strain S2308. This demonstrated that ExsA is critical for full bacterial virulence. The B. abortus exsA deletion mutant was used as a live vaccine candidate. Challenge experiments revealed that the exsA mutant strain induced superior protective immunity in BALB/c mice compared to the protective immunity induced by strain S19 or RB51" ; rdfs:label "Brucella abortus exsA mutant vaccine" ; rdfs:subClassOf obo:VO_0001134 . obo:VO_0002813 obo:IAO_0000115 "A vaccine that prevents or treats a non-infectious disease." ; obo:IAO_0000117 "YH, RS" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/12831367" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "There are mainly five types of non-infectious diseases, which are diabetes, allergies, cardiovascular diseases, cancer and genetic diseases. URL: http://www.ychlpyss.edu.hk/~bio/share/0405/f6homework/Non-infectious%20disease/noninfectiousdisease(ths).htm" ; rdfs:label "non-infectious disease vaccine" ; rdfs:subClassOf obo:VO_0005503 . obo:VO_0002814 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002810 ; a owl:Class ; rdfs:comment "Mutants manB and manA were attenuated in Brucella melitensis and provided protection against challenge in mice's livers", "Unmarked rough B. abortus and B. melitensis deletion mutants of manBA (including manA and manB) were attenuated. These mutants provided protection against virulent Brucella challenge in mice" ; rdfs:label "obsolete B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002815 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A mucR mutant has a significantly reduced degree of colonization in mice and protects against wild type B. melitensis 16M" ; rdfs:label "B. melitensis mucR mutant vaccine" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_29459 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:VO_0002565 ] ) ] ] . obo:VO_0002816 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A omp25 mutant is attenuated and provides protection against challenge in mice" ; rdfs:label "B. melitensis omp25 mutant vaccine" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_29459 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:VO_0002566 ] ) ] ] . obo:VO_0002817 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A omp31 mutant in Brucella melitensis was attenuated and provided protection against challenge in mice" ; rdfs:label "B. melitensis omp31 mutant vaccine" ; rdfs:subClassOf obo:VO_0001135, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_29459 [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:VO_0002567 ] ) ] ] . obo:VO_0002818 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A pgk mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus" ; rdfs:label "Brucella abortus pgk mutant vaccine" ; rdfs:subClassOf obo:VO_0001134 . obo:VO_0002819 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A pgm mutant is attenuated in mice and induces significant protection from challenge with wild type B. abortus" ; rdfs:label "Brucella abortus pgm mutant vaccine" ; rdfs:subClassOf obo:VO_0001134 . obo:VO_0002820 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002821" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A purE/purK mutant of B. melitensis 16M was attenuated in mice when given intraperitoneally. Nine weeks after immunization, mice were protected from challenge with wild type B. melitensis", "Mice infected with delta purE201 developed only five to eight times normal spleen weight at 1 week p.i. and produced no interleukin-6 in their serum, which is much lower than the mice infected with the parental strain (16M)" ; rdfs:label "B. melitensis WR201 (16MΔpurEK)" ; rdfs:subClassOf obo:VO_0001135 . obo:VO_0002821 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002820 ; a owl:Class ; rdfs:comment "A purE/purK mutant of B. melitensis 16M was attenuated in mice when given intraperitoneally. Nine weeks after immunization, mice were protected from challenge with wild type B. melitensis" ; rdfs:label "obsolete B. melitensis WR201 (16MŒîpurEK)" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002822 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002810 ; a owl:Class ; rdfs:comment "A virB2 mutant is attenuated in Brucella melitensis and provides protection in mice" ; rdfs:label "obsolete B. abortus and B. melitensis mutants with unmarked deletion of asp24, virB2, or manBA" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002823 obo:IAO_0000115 "A vaccine that prevents or treats arthritis." ; obo:IAO_0000117 "YH, RS" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/12956615" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "arthritis vaccine" ; rdfs:subClassOf obo:VO_0002813 . obo:VO_0002824 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Deletion of gene znuA attenuates Brucella abortus and this live attenuated vaccine was challenged in mice. These mice showed significantly fewer spenic CFU" ; rdfs:label "live attenuated B. abortus with deletion of znuA" ; rdfs:subClassOf obo:VO_0001134 . obo:VO_0002825 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "The aroC deletion in the resultant mutant, designated A2ŒîaroC, was confirmed by PCR, Southern hybridization and failure of the mutant to grow in a defined medium without aromatic compounds. The constructed unmarked aroC mutant of B. pseudomallei is attenuated in both BALB/c and C57Bl/6 mice and is able to confer significant protection in C57Bl/6 mice" ; rdfs:label "Burkholderia pseudomallei aroC deletion mutant vaccine" ; rdfs:subClassOf obo:VO_0012175 . obo:VO_0002826 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An asd mutant is highly attenuated in mice. This mutant was also able to protect against acute inhalation melioidosis caused by challenge with wild type B. pseudomallei" ; rdfs:label "Burkholderia pseudomallei asd mutant vaccine" ; rdfs:subClassOf obo:VO_0012175 . obo:VO_0002827 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Mice that were challenged with a higher dose of mutant 56:65 purM were protected" ; rdfs:label "Burkholderia pseudomallei purM mutant vaccine" ; rdfs:subClassOf obo:VO_0012175 . obo:VO_0002828 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Although 30:93a purN -immunized mice were challenged with a 10-fold higher dose of WT E8, mice were strongly protected and showed no signs of clinical illness until the experiment was terminated" ; rdfs:label "Burkholderia pseudomallei purN mutant vaccine" ; rdfs:subClassOf obo:VO_0012175 . obo:VO_0002829 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A crp mutant is attenuated in zebrafish and catfish that were immunized intramuscularly and intracoelomically, respectively. Six weeks after immunization, both zebrafish and catfish were protected from challenge with wild type E. ictaluri" ; rdfs:label "E. ictaluri crp mutant vaccine" ; rdfs:subClassOf obo:VO_0001521 . obo:VO_0002830 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" ; rdfs:label "Edwardsiella tarda aroC mutant vaccine" ; rdfs:subClassOf obo:VO_0002506 . obo:VO_0002831 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002835" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%", "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" ; rdfs:label "Edwardsiella tarda aroC/slyA mutant vaccine" ; rdfs:subClassOf obo:VO_0002506 . obo:VO_0002832 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002834" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%", "An aroC mutant is attenuated in zebra fish. The aroC mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 68.3%" ; rdfs:label "Edwardsiella tarda aroC/esrC mutant vaccine" ; rdfs:subClassOf obo:VO_0002506 . obo:VO_0002833 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An esrB mutant is highly attenuated in fish (turbot), with an LD50 of 10(8.1)cfu/fish. Vaccination with this mutant elicited significant protection from wild type E. tarda" ; rdfs:label "Edwardsiella tarda esrB mutant vaccine" ; rdfs:subClassOf obo:VO_0002506 . obo:VO_0002834 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002832 ; a owl:Class ; rdfs:comment "An aroC and esrC mutant is attenuated in zebra fish. This mutant is also protective against challenge with wild type E. tarda and has a relative percent survival of 71.3%" ; rdfs:label "obsolete Edwardsiella tarda aroC/esrC mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002835 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002831 ; a owl:Class ; rdfs:comment "An aroC and slyA mutant is attenuated in zebra fish. This mutant is also protective against challenge from wild type E. tarda, resulting in a relative percent survival of 80.1%" ; rdfs:label "obsolete Edwardsiella tarda aroC/slyA mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002836 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A carAB mutant is attenuated in turkeys and induces significant protection from challenge with wild type E. coli" ; rdfs:label "Escherichia coli carAB mutant vaccine" ; rdfs:subClassOf obo:VO_0000962 . obo:VO_0002837 obo:IAO_0000115 "A vaccine that prevents or treats an autoimmune disease." ; obo:IAO_0000117 "YH, RS" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/15196997" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "autoimmune disease vaccine" ; rdfs:subClassOf obo:VO_0002813 . obo:VO_0002838 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A ler deletion mutant derived from wild-type EHEC O157:H7 86-24 was constructed by use of suicide vector pCVD442. Following challenge of 7-day-old suckling mice with O157:H7 EDL933, 75.2% born to group B mothers (immunized with F25) sur- vived, as did 83.0% born to group C mothers (immunized with F105). The surviving suckling mice consistently gained body weight. Only 16.8% of sucking mice born to control group mice survived the challenge" ; rdfs:label "Escherichia coli ler mutant vaccine" ; rdfs:subClassOf obo:VO_0000962 . obo:VO_0002839 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Deletion of waaL results in a strain that stimulates enhanced urothelial cytokine secretion, which is an enhanced innate immune response. Inoculation with the vaccine strain protected mice against challenge with a broad range of clinical uropathogenic E. coli isolates and produced immunity that lasted ‚©æ8 weeks" ; rdfs:label "Escherichia coli rfaL mutant vaccine" ; rdfs:subClassOf obo:VO_0000962 . obo:VO_0002840 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "There was a deletion in gene capB of F. tularensis live vaccine strain. LVS capB, while much less virulent than LVS, induces potent protective immunity against lethal LVS i.n. challenge in mice, comparable to that induced by LVS" ; rdfs:label "Francisella tularensis capB mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002841 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A clpB mutant in Francisella tularensis subspecies tularensis strain SCHU S4 was attenuated and provided protection against aerosol challenge in mice" ; rdfs:label "Francisella tularensis clpB mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002842 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A FTL0552 mutant in Francisella tularensis was attenuated and provided partial protection in mice against challenge with a lethal dose of the virulent SchuS4 strain when compared to naive mice" ; rdfs:label "Francisella tularensis FTL0552 mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002843 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An FTT0918 mutant showed significantly reduced virulence in mice. Mice that recovered from infection with the mutant were protected 2 months later from challenge with wild type F. tularensis" ; rdfs:label "Francisella tularensis FTT0918 mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002844 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A galU mutant is attenuated in mice, with only transient weight loss observed. Two months after inoculation, mice were challenge with wild type F. tularensis and were protected, once again only experiencing transient weight loss" ; rdfs:label "Francisella tularensis galU mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002845 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A guaA mutant is highly attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS" ; rdfs:label "Francisella tularensis guaA mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002846 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A guaB mutant is attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS" ; rdfs:label "Francisella tularensis guaB mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002847 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS). Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge" ; rdfs:label "Francisella tularensis IglB mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002848 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000307 ; a owl:Class ; rdfs:comment "An iglC mutant is highly attenuated in mice. Inoculated mice were challenged 30 days later with wild type F. tularensis and were highly protected" ; rdfs:label "obsolete KKF24" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002849 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002851" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A purMCD mutant in Francisela tularensis was attenuated. A low dosage of F. tularensis LVS delta purMCD mutant provided protection against challenge in mice", "A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain" ; rdfs:label "Francisella tularensis purMCD mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002850 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Mice, which had been immunized with at least 6.95√ó103 cfu of F. tularensis U112 purF::Cm, were protected against the subsequent F. tularensis subspecies novicida challenge" ; rdfs:label "Francisella tularensis purF mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002851 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002849 ; a owl:Class ; rdfs:comment "A purMCD mutant in Francisella tularensis was attenuated. A low dose of the F. tularensis LVS delta purMCD mutant provided protection against subsequent lethal challenge with the LVS parental strain" ; rdfs:label "obsolete Francisella tularensis purMCD mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002852 obo:IAO_0000115 "A Streptococcus vaccine against Streptococcus pyogenes infection." ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pyogenes vaccine" ; rdfs:subClassOf obo:VO_0000772, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] . obo:VO_0002853 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A sodC mutant in Francisella tularensis subspecies holarctica was attenuated and provided protection and cleared the infection against lethal challenge in nearly 50% of the mice infected with the ŒîsodC mutant" ; rdfs:label "Francisella tularensis sodC mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002854 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A wbtA mutant in Francisella tularensis was attenuated and provided protection in mice against challenge with an otherwise lethal dose of either F. tularensis LVS or a fully virulent clinical isolate of F. tularensis type B" ; rdfs:label "Francisella tularensis wbtA mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002855 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A wbtI mutant is attenuated in mice. The mutant protected against a low dose challenge with the parental strain, but was less effective against higher doses. However, increasing the immunization dose increased the resistance to higher challenge doses" ; rdfs:label "Francisella tularensis wbtI mutant vaccine" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0002856 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in mice and induced significant protection after two doses from challenge with wild type M. haemolytica" ; rdfs:label "Mannheimia haemolytica aroA mutant vaccine" ; rdfs:subClassOf obo:VO_0001523 . obo:VO_0002857 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An lpd mutant is highly attenuated in chickens and induces significant protection from challenge with wild type M. gallisepticum" ; rdfs:label "Mycoplasma gallisepticum lpd mutant vaccine" ; rdfs:subClassOf obo:VO_0000949 . obo:VO_0002858 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002860" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A metH mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis", "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" ; rdfs:label "Neisseria meningitidis metH/siaD mutant vaccine" ; rdfs:subClassOf obo:VO_0000053 . obo:VO_0002859 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002861" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis", "An rfaF mutant, in combination with a siaD mutation, is attenuated in mice and induces significant protection from challenge with wild type N. meningitidis" ; rdfs:label "Neisseria meningitidis rfaF/siaD mutant vaccine" ; rdfs:subClassOf obo:VO_0000053 . obo:VO_0002860 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002858 ; a owl:Class ; rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" ; rdfs:label "obsolete Neisseria meningitidis metH/siaD mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002861 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002859 ; a owl:Class ; rdfs:comment "A siaD mutant, in combination with either a metH or rfaF mutation, is attenuated in mice and induces protection from challenge with wild type N. meningitidis" ; rdfs:label "obsolete Neisseria meningitidis rfaF/siaD mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002862 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in calves and induces significant protection from challenge with wild type P. multocida" ; rdfs:label "Pasteurella multocida aroA mutant vaccine" ; rdfs:subClassOf obo:VO_0000053 . obo:VO_0002863 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA mutant is attenuated in mice and induced significant protection from challenge with wild type S. typhi Ty2" ; rdfs:label "Salmonella typhi aroA mutant vaccine" ; rdfs:subClassOf obo:VO_0000671 . obo:VO_0002864 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002866" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"", "Inactivation of AroD results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ; rdfs:label "Aro-deleted S. Typhi" ; rdfs:subClassOf obo:VO_0000671 . obo:VO_0002865 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Inactivation of AroC results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ; rdfs:label "CVD 908-htrA" ; rdfs:subClassOf obo:VO_0000671 . obo:VO_0002866 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002864 ; a owl:Class ; rdfs:comment "Inactivation of AroD results in attenuation in humans, and the deletions of both AroC and AroD provide a high level of safety against restoration of pathogenicity by recombination. An aroC/aroD-deleted derivative of S. Typhi strain Ty2 (the parent strain of Ty21a) is designated the strain \"CVD 908\"" ; rdfs:label "obsolete Aro-deleted S. Typhi" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002867 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium" ; rdfs:label "Salmonella Typhimurium asd mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002868 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002906" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An asd mutant, alone or in combination with a rfc mutation, is attenuated in mice and induces significant protection from challenge with wild type Salmonella typhimurium", "An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ; rdfs:label "Salmonella Typhimurium asd/rfc mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002869 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An atpA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ; rdfs:label "Salmonella Typhimurium atpA mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002870 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002875" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A cbiA mutant, in combination with a cobS mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis", "A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis" ; rdfs:label "Salmonella Gallinarum cbiA/cobS mutant vaccine" ; rdfs:subClassOf obo:VO_0002508 . obo:VO_0002871 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002884" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis", "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective, and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis" ; rdfs:label "Salmonella Enteritidis guaBA/clpP mutant vaccine" ; rdfs:subClassOf obo:VO_0002509 . obo:VO_0002872 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002873", "VO:0002874" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" ; rdfs:label "Salmonella Typhimurium clpP mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002873 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002872 ; a owl:Class ; rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP mutant vaccine (merged to VO_0002872)" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002874 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002872 ; a owl:Class ; rdfs:comment "A mutation in clpP (CS2007) causes hyperflagellation. These hyperflagellated bacteria are attenuated in mice, and an LD50 for CS2007 could not be determined because mice did not die after inoculation with the highest dose. CS2007 also elicited protection in mice from challenge with wild type S. typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002872)" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002875 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002870 ; a owl:Class ; rdfs:comment "A cobS mutant, in combination with a cbiA mutation, is attenuated in chickens and induces significant protection from challenge with wild type S. Gallinarum. This mutant was also able to provide some protection against S. Enteritidis" ; rdfs:label "obsolete Salmonella Gallinarum cbiA/cobS mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002876 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002891", "VO:0002907" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ; rdfs:label "Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002877 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002894" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A cpxR mutant, in combination with a lon mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum", "A lon mutant, in combination with a cpxR mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ; rdfs:label "Salmonella Gallinarum cpxR/Ion mutant vaccine" ; rdfs:subClassOf obo:VO_0002508 . obo:VO_0002878 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002880" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium" ; rdfs:label "Salmonella Typhimurium cya/crp mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002879 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A crp mutant is attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ; rdfs:label "Salmonella Gallinarum crp mutant vaccine" ; rdfs:subClassOf obo:VO_0002508 . obo:VO_0002880 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002878 ; a owl:Class ; rdfs:comment "A cya and crp mutant is attenuated in mice. Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium cya/crp mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002881 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002889", "VO:0002890" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A fliC mutant, in combination with a guaB mutant, is attenuated in mice and chickens and induces significant protection from challenge with wild type S. enterica", "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica", "JZ: based on comment,VO:0002890 should be 'Salmonella enterica fliC/guaB mutant vaccine'." ; rdfs:label "Salmonella enterica fliC/guaB mutant vaccine" ; rdfs:subClassOf obo:VO_0002509 . obo:VO_0002882 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A guaBA, clpP, and fliD mutant (CVD 1923) is attenuated in mice after oral immunization. This mutant is also protective, with a vaccine efficacy of 80% in mice against wild type challenge from Salmonella Typhimurium" ; rdfs:label "Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002883 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A gal E mutant in strain Ty2 was isolated, attenuated, and protected mice against lethal challenge" ; rdfs:label "Salmonella Typhi galE mutant vaccine" ; rdfs:subClassOf obo:VO_0000671 . obo:VO_0002884 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002871 ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1941) is attenuated in mice after oral immunization. This mutant is also protective in mice and had a vaccine efficacy of 76% against challenge with wild type Salmonella Enteritidis" ; rdfs:label "obsolete Salmonella Enteritidis guaBA/clpP mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002885 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002886", "VO:0002887", "VO:0002888" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ; rdfs:label "Salmonella Typhimurium guaBA/clpP mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002886 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002885 ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002885)" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002887 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002885 ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002888 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002885 ; a owl:Class ; rdfs:comment "A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine (merged to VO_0002885)" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002889 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002881 ; a owl:Class ; rdfs:comment "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica" ; rdfs:label "obsolete Salmonella enterica fliC/guaB mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002890 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002881 ; a owl:Class ; rdfs:comment "A guaB mutant, in combination with a fliC mutant, is attenuated in mice and chickens and induced significant protection from challenge with wild type S. enterica" ; rdfs:label "obsolete Salmonella Enteritidis guaBA/clpP mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002891 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002876 ; a owl:Class ; rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ; rdfs:label "obsolete Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002892 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Oral immunization with the Salmonella hfq deletion mutant efficiently protects mice against subsequent oral challenge with virulent strain of Salmonella Typhimurium" ; rdfs:label "Salmonella Typhimurium hfq mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002893 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A htrA mutant in Salmonella typhimurium is attenuated and provides protection in mice against an oral challenge with virulent S. typhimurium SL1344" ; rdfs:label "Salmonella Typhimurium htrA mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002894 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002877 ; a owl:Class ; rdfs:comment "A lon mutant, in combination with a cpxR mutation, is highly attenuated in mice and induces significant protection from challenge with wild type S. gallinarum" ; rdfs:label "obsolete Salmonella Gallinarum cpxR/Ion mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002895 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002896", "VO:0002898" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An lppA mutant, in combination with an lppB/msbB mutation, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium", "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium", "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" ; rdfs:label "Salmonella Typhimurium IppA/IppB/msbB" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002896 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002895 ; a owl:Class ; rdfs:comment "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium IppA/IppB/msbB" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002897 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002899" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An lppB mutant, in combination with an msbB mutant or an msbB/lppA mutant, is attenuated in mice and induces significant protection from challenge with wild type S. Typhimurium", "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" ; rdfs:label "Salmonella Typhimurium IppB/msbB mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002898 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002895 ; a owl:Class ; rdfs:comment "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium IppA/IppB/msbB" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002899 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002897 ; a owl:Class ; rdfs:comment "An msbB mutant, in combination with an lppB or lppAB mutation, is attenuated in mice and induces significant protection from challenge with S. Typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium IppB/msbB mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002900 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "In a pig infection experiment including two oral immunizations with SalmoporcDeltaompD (OmpD, nmpC) and challenge with a multiresistant S. enterica serovar Typhimurium DT104 clinical isolate, we confirmed the protective efficacy of SalmoporcDeltaompD in pigs, showing a significant reduction of both clinical symptoms and colonization of lymph nodes and intestinal tract" ; rdfs:label "Salmonella Typhimurium ompD/nmpC mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002901 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A nuoG mutant is attenuated in chickens and induced significant protection from challenge with wild type S. Gallinarum" ; rdfs:label "Salmonella Gallinarum nuoG mutant vaccine" ; rdfs:subClassOf obo:VO_0002508 . obo:VO_0002902 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An ompR mutant is attenuated in mice after oral challenge. Twenty eight days after immunization, mice were challenged with wild type S. typhimurium and were significantly protected" ; rdfs:label "Salmonella Typhimurium ompR mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002903 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Three S. typhi deletion mutants (phoP, rpoS, and rpoS-phoP double mutant) were constructed and characterized with respect to invasiveness, virulence, and protective immune response compared with wild-type Ty2. All S. typhi mutants showed an increase in the specific serum IgG levels and T-cell-mediated immunity, and showed equal protection abilities against a wild-type Ty2 challenge after two rounds of immunization in BALB/c mice" ; rdfs:label "Salmonella Typhi phoP mutant vaccine" ; rdfs:subClassOf obo:VO_0000671 . obo:VO_0002904 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A poxA mutant is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ; rdfs:label "Salmonella Typhimurium poxA mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002905 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002910" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum" ; rdfs:label "Salmonella Gallinarum relA/spoT mutant vaccine" ; rdfs:subClassOf obo:VO_0002508 . obo:VO_0002906 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002868 ; a owl:Class ; rdfs:comment "An rfc mutant, in combination with an asd mutation, is attenuated in mice and induces significant protection from challenge with wild type S. typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium asd/rfc mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002907 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002876 ; a owl:Class ; rdfs:comment "A gyrA-cpxA-rpoB Salmonella Typhimurium mutant was attenuated and protected against challenge in pigs" ; rdfs:label "obsolete Salmonella Typhimurium gyrA/cpxA/rpoB mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002908 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Immunizations with Salmonella typhimurium rpoS and rpoS aroA mutants protected susceptible BALB/c mice against subsequent oral challenge with virulent S. typhimurium. When administered orally or intraperitoneally, rpoS derivatives of the mouse-virulent S. typhimurium strains, C52 and SL1344, were highly attenuated and were efficient single-dose live vaccines" ; rdfs:label "Salmonella Typhimurium rpoS mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002909 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A ruvB mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "Salmonella Typhimurium ruvB mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002910 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002905 ; a owl:Class ; rdfs:comment "A ppGpp-defective Salmonella Gallinarum, which is attained by mutating the relA and spoT genes, is attenuated in chickens and induces protection from oral challenge with wild type S. Gallinarum" ; rdfs:label "obsolete Salmonella Gallinarum relA/spoT mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002911 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A surA mutant (BRD1115) is attenuated in BALB/c mice and induces protection from challenge with wild type S. typhimurium" ; rdfs:label "Salmonella Typhimurium surA mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002912 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A tolA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "Salmonella Typhimurium tolA mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002913 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A trxA mutant is attenuated in mice and induced significant protection from challenge with wild type S. Typhimurium" ; rdfs:label "Salmonella Typhimurium trxA mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002914 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A wecA mutant (DSM645) is attenuated in C57BL/6J mice through i.p. and oral immunization. This mutant also protects against challenge with S. typhimurium strains TML and SL1344 30 days after immunization" ; rdfs:label "Salmonella Typhimurium wecA mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002915 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002916", "VO:0002917" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ; rdfs:label "Salmonella Typhimurium znuABC mutant vaccine" ; rdfs:subClassOf obo:VO_0002507 . obo:VO_0002916 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002915 ; a owl:Class ; rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium znuABC mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002917 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002915 ; a owl:Class ; rdfs:comment "A znuABC mutant is attenuated in mice and induced significant protection against a challenge infection in the large intestine with wild type Salmonella typhimurium" ; rdfs:label "obsolete Salmonella Typhimurium znuABC mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002918 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002920 ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "obsolete CVD 1204(pGA1-CS2)" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002919 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000676 ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "obsolete S. dysenteriae 1 strain WRSd1" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002920 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002918", "VO:0002926" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "S. flexneri 2a strain CVD 1203" ; rdfs:subClassOf obo:VO_0000680 . obo:VO_0002921 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000678 ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "obsolete S. sonnei strain WRSS1" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002922 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri" ; rdfs:label "S. flexneri strain Sfl 124" ; rdfs:subClassOf obo:VO_0000680 . obo:VO_0002923 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroD mutant is highly attenuated in monkeys and induces significant protection from challenge with wild type S. flexneri" ; rdfs:label "Shigella flexneri aroD mutant vaccine" ; rdfs:subClassOf obo:VO_0000680 . obo:VO_0002924 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An envZ mutant (SC433) is greatly decreased in virulence in macaque monkeys, though some mild clinical signs were still recorded. This mutant is also highly protective against a challenge of wild type S. flexneri delivered 1 month after inoculation" ; rdfs:label "Shigella flexneri envZ mutant vaccine" ; rdfs:subClassOf obo:VO_0000680 . obo:VO_0002925 obo:IAO_0000115 "a Brucella vaccine against infection wtih B. ovis" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella ovis vaccine" ; rdfs:subClassOf obo:VO_0000025, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_236 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_236 ] . obo:VO_0002926 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002920 ; a owl:Class ; rdfs:comment "An aroA and virG mutant (CVD 1203) is attenuated in guinea pigs, as shown by the Sereny test. Guinea pigs inoculated with CVD 1203 were also protected from challenge with wild type S. flexneri" ; rdfs:label "obsolete SC602" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002927 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:VO_0001818 "3153" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A virG, senA, senB, and msbB2 mutant (WRSs3) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs3 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "Shigella sonnei virG/senA/senB/msbB2 mutant vaccine" ; rdfs:subClassOf obo:VO_0000679 . obo:VO_0002928 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002929", "VO:0002930", "VO:0002931" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "Shigella sonnei virG/senA/senB mutant vaccine" ; rdfs:subClassOf obo:VO_0000679 . obo:VO_0002929 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002928 ; a owl:Class ; rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002930 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002928 ; a owl:Class ; rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "obsolete Shigella sonnei virG/senA/senB mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002931 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002928 ; a owl:Class ; rdfs:comment "A virG, senA, and senB mutant (WRSs2) is attenuated in guinea pigs and induced significant protection from challenge with wild type S. sonnei. Attenuation and protection from WRSs2 is comparable to live attenuated vaccine strain WRSS1" ; rdfs:label "obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002932 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000678 ; a owl:Class ; rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei" ; rdfs:label "obsolete Shigella sonnei virG/senA/senB mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002933 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000678 ; a owl:Class ; rdfs:comment "A virG mutant (WRSS1) is attenuated in guinea pigs and induced significant protection from challenge with wild type Shigella sonnei" ; rdfs:label "obsolete Shigella sonnei virG/senA/senB/msbB2 mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002934 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A hemA mutant is highly attenuated in mice and rabbits and induces protection from challenge with wild type V. cholerae in rabbits" ; rdfs:label "Vibrio cholerae hemA mutant vaccine" ; rdfs:subClassOf obo:VO_0000763 . obo:VO_0002935 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in mice, and after 3 doses induces significant protection from challenge with wild type Y. enterocolitica" ; rdfs:label "Yersinia enterocolitica aroA mutant vaccine" ; rdfs:subClassOf obo:VO_0012186 . obo:VO_0002936 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A htrA mutant in Yersinia enterocolitica was attenuated and provided partial protection against challenge in mice" ; rdfs:label "Yersinia enterocolitica htrA mutant vaccine" ; rdfs:subClassOf obo:VO_0012186 . obo:VO_0002937 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A ompR mutant in Yersinia enterocolitica was attenuated and provided a partial protection from challenge in mice" ; rdfs:label "Yersinia enterocolitica ompR mutant vaccine" ; rdfs:subClassOf obo:VO_0012186 . obo:VO_0002938 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A sodA mutant in Yersinia enterocolitica was highly attenuated and mice immunized with a single oral dose of the mutant strain were protected against a lethal oral-challenge infection with wild-type Y. enterocolitica" ; rdfs:label "Yersinia enterocolitica sodA mutant vaccine" ; rdfs:subClassOf obo:VO_0012186 . obo:VO_0002939 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002940" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "Yersinia pestis guaBA mutant vaccine" ; rdfs:subClassOf obo:VO_0000648 . obo:VO_0002940 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002939 ; a owl:Class ; rdfs:comment "A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "obsolete Yersinia pestis guaBA mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002941 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An IpxM mutant is attenuated in mice and guinea pigs. This mutant also conferred modest protection from challenge with wild type Y. pestis in Balb/c mice and significant protection in guinea pigs and outbred mice" ; rdfs:label "Yersinia pestis IpxM mutant vaccine" ; rdfs:subClassOf obo:VO_0000648 . obo:VO_0002942 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An nlpD mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "Yersinia pestis nlpD mutant vaccine" ; rdfs:subClassOf obo:VO_0000648 . obo:VO_0002943 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A pcm mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "Yersinia pestis pcm mutant vaccine" ; rdfs:subClassOf obo:VO_0000648 . obo:VO_0002944 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002945" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis" ; rdfs:label "Yersinia pestis smpB/ssrA mutant vaccine" ; rdfs:subClassOf obo:VO_0000648 . obo:VO_0002945 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002944 ; a owl:Class ; rdfs:comment "An smpB mutant, in combination with an ssrA mutation, is attenuated in mice and induces significant protection from challenge with wild type Y. pestis" ; rdfs:label "obsolete Yersinia pestis smpB/ssrA mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002946 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A yopH mutant is highly attenuated in mice and induced significant protection from challenge with wild type Y. pestis" ; rdfs:label "Yersinia pestis yopH mutant vaccine" ; rdfs:subClassOf obo:VO_0000648 . obo:VO_0002947 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A phoP mutant in Yersinia pseudotuberculosis (Yptb) was attenuated and provided protection against oral challenge with virulent Yptb in mice" ; rdfs:label "Yersinia pseudotuberculosis phoP mutant vaccine" ; rdfs:subClassOf obo:VO_0002510 . obo:VO_0002948 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An aroA mutant is highly attenuated in rainbow trout and induces significant protection from challenge with wild type Y. ruckeri" ; rdfs:label "Yersinia ruckeri aroA mutant vaccine" ; rdfs:subClassOf obo:VO_0001035 . obo:VO_0002949 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A thymidine kinase-deficient mutant (B8-D53) showed no detectable thymidine kinase-inducing activity and was attenuated in calves. B8-D53 also induced protection from challenge with wild type BHV-1" ; rdfs:label "Bovine herpesvirus 1 UL23 mutant vaccine" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482 . obo:VO_0002950 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A deletion of BHV-1 gE gene in strain A is considered as a live attenuated vaccine. After challenge, vaccinated calves were protected against disease and virus shedding was reduced" ; rdfs:label "Bovine herpesvirus 1 US8 (gE) mutant vaccine" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482 . obo:VO_0002951 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A glycoprotein G deletion in bovine respiratory syncytial virus(rBRSV) and recombinant rBRSV was attenuated and provided protection against a BRSV challenge infection in calves" ; rdfs:label "Bovine respiratory syncytial virus glycoprotein G mutant vaccine" ; rdfs:subClassOf obo:VO_0001507 . obo:VO_0002952 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An N269A/Q mutation in the E(rns) protein created an attenuated mutant in swine. This mutant was able to induce effective protection in swine against challenge with wild type CSFV" ; rdfs:label "Classical swine fever virus E(rns) mutant vaccine" ; rdfs:subClassOf obo:VO_0001012 . obo:VO_0002953 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An N to A amino acid substitution was made in the N594 site of the E1 glycoprotein, resulting in attenuation of the virus in swine. This attenuated virus induced protection against challenge with wild type CSFV" ; rdfs:label "Classical swine fever virus E1 mutant vaccine" ; rdfs:subClassOf obo:VO_0001012 . obo:VO_0002954 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A E2 mutant in Classical swine fever virus is attenuated and provides protection in pigs after oronasal vaccination (not intradermal vaccination) against lethal challenge dose of CSFV strain Eystrup" ; rdfs:label "Classical swine fever virus E2 mutant vaccine" ; rdfs:subClassOf obo:VO_0001012 . obo:VO_0002955 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A glycoprotein E mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice" ; rdfs:label "Equid herpesvirus gE mutant vaccine" ; rdfs:subClassOf obo:VO_0001486 . obo:VO_0002956 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A glycoprotein I mutant is attenuated in mice and hamsters and induced significant protection from challenge with wild type Equid herpesvirus in mice" ; rdfs:label "Equid herpesvirus gI mutant vaccine" ; rdfs:subClassOf obo:VO_0001486 . obo:VO_0002957 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A thymidine kinase-deficient mutant (PR1) is attenuated in mice and induced significant protection from challenge with wild type EHV-1 5 weeks after vaccination. In foals, PR1 also showed attenuation; however, the mutant induced only partial protection from challenge with EHV-1" ; rdfs:label "Equid herpesvirus TK mutant vaccine" ; rdfs:subClassOf obo:VO_0001486 . obo:VO_0002958 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A thymidine kinase-deficient mutant (C7301dlTK) is attenuated in cats and induced significant protection from wild type FHV-1 4 weeks after vaccination" ; rdfs:label "Feline herpesvirus 1 UL23 mutant vaccine" ; rdfs:subClassOf obo:VO_0001487 . obo:VO_0002959 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Feline immunodeficiency virus (FIV) made defective in the accessory gene ORF-A were previously shown to be greatly attenuated in its ability to replicate in lymphocytes but to grow normally or near normally in other cell types. 3/9 vaccinees (cats) showed no evidence of the challenge virus over a 15-month observation period. In the other vaccinees, the challenge virus was predominant for various periods of time, but pre-existing viral loads and CD4 lymphocyte counts were either unaffected or altered only marginally and transiently" ; rdfs:label "Feline immunodeficiency virus ORF-A mutant vaccine" ; rdfs:subClassOf obo:VO_0001508 . obo:VO_0002960 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A vif mutant in feline immunodeficiency virus was attenuated and FIV-pPPRŒîvif proviral DNA protected cats against challenge with the homologous FIV-PPR biological isolate." ; rdfs:label "Feline immunodeficiency virus vif mutant vaccine" ; rdfs:subClassOf obo:VO_0001508 . obo:VO_0002961 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002962", "VO:0002963" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "Feline infectiour peritonitis virus 3abc mutant vaccine" ; rdfs:subClassOf obo:VO_0001504 . obo:VO_0002962 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002961 ; a owl:Class ; rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "obsolete Feline infectiour peritonitis virus 3abc mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002963 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002961 ; a owl:Class ; rdfs:comment "A 3abc deletion mutant in Feline infectious peritonitis virus (FIPV) was attenuated and provided protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "obsolete Feline infectiour peritonitis virus 3abc mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002964 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002965" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "Feline infectious peritonitis virus 7ab mutant vaccine" ; rdfs:subClassOf obo:VO_0001504 . obo:VO_0002965 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002964 ; a owl:Class ; rdfs:comment "A 7ab deletion mutant in Feline infectious peritonitis virus is attenuated and provides protection against virulent FIPV strain 79-1146 challenge in kittens" ; rdfs:label "obsolete Feline infectious peritonitis virus 7ab mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002966 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A UL0 mutant in infectious laryngotracheitis virus (ILTV) was attenuated. Chickens immunized with UL0-negative ILTV were protected from clinical disease after subsequent infection with virulent ILTV" ; rdfs:label "Gallid herpesvirus 1 UL0 mutant vaccine" ; rdfs:subClassOf obo:VO_0001488 . obo:VO_0002967 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A thymidine-kinase mutant is attenuated in chickens and induced protection from challenge with wild type GHV-1" ; rdfs:label "Gallid herpesvirus 1 UL23 mutant vaccine" ; rdfs:subClassOf obo:VO_0001488 . obo:VO_0002968 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A UL47 mutant in avian infectious laryngotracheitis virus is attenuated and provides protection in chicken against subsequent challenge infection with virulent ILTV" ; rdfs:label "Gallid herpesvirus 1 UL47 mutant vaccine" ; rdfs:subClassOf obo:VO_0001488 . obo:VO_0002969 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Researchers generated a series of woodchuck hepatitis virus (WHV) X mutants. Woodchucks inoculated with X mutants, including those with no serologic evidence of infection, were protected from later challenge with infectious Woodchuck Hepatitis Virus, suggesting previous infection with resulting protective immunity" ; rdfs:label "Hepatitis B virus X protein mutant vaccine" ; rdfs:subClassOf obo:VO_0000644 . obo:VO_0002970 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "KOS-gDA3C is attenuated with mutations in gD gene in causing skin lesions at the inoculation and zosteriform sites, yet it is as effective as rKOS-gDA3C in protecting mice against HSV-1 challenge" ; rdfs:label "Herpes simplex virus 1 gD mutant vaccine" ; rdfs:subClassOf obo:VO_0000958 . obo:VO_0002971 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A gH mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1" ; rdfs:label "Herpes simplex virus 1 gH mutant vaccine" ; rdfs:subClassOf obo:VO_0000958 . obo:VO_0002972 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A live-attenuated HSV-2 ICP0 virus provides significant protection against wild-type HSV-2 (MS strain) challenge in mice" ; rdfs:label "Herpes simplex virus 2 ICP0 mutant vaccine" ; rdfs:subClassOf obo:VO_0012168 . obo:VO_0002973 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A thymidine kinase-deficient (TK) mutant was found to be attenuated in mice. This mutant induced complete protection from challenge with wild type HSV" ; rdfs:label "Herpes simplex virus 1 TK mutant vaccine" ; rdfs:subClassOf obo:VO_0000958 . obo:VO_0002974 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A UL29 mutant is attenuated in mice and induces significant protection from challenge with wild type HSV-1" ; rdfs:label "Herpes simplex virus 1 UL29 mutant vaccine" ; rdfs:subClassOf obo:VO_0000958 . obo:VO_0002975 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0011423 ; a owl:Class ; rdfs:comment "An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from <10% of vaccinated mice compared with 100% of mock-vaccinated mice" ; rdfs:label "obsolete Herpes simplex virus type 1 DNA vaccine encoding GE" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002976 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A G mutant is attenuated in African green monkeys and induces protection from challenge with wild type HMPV" ; rdfs:label "Human metapneumovirus G protein mutant vaccine" ; rdfs:subClassOf obo:VO_0002511 . obo:VO_0002977 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An M2-2 mutant is attenuated in African green monkeys and induced protection from challenge with wild type HMPV" ; rdfs:label "Human metapneumovirus M2-2 mutant vaccine" ; rdfs:subClassOf obo:VO_0002511 . obo:VO_0002978 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An M2-2 mutant of human respiratory syncytial virus A2 is attenuated in African green monkeys. When challenged with wild type RSV, two doses provided complete protection against challenge in the lower respiratory tract and a significant reduction of the challenge virus in the upper respiratory tract" ; rdfs:label "Human Respiratory Syncytial Virus M2-2 mutant vaccine" ; rdfs:subClassOf obo:VO_0002512 . obo:VO_0002979 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A mutation in the non-virion protein of IHNV causes attenuated growth in rainbow trout and is able to provide significant protection from subsequent challenge with wild type IHNV" ; rdfs:label "Infectious Hematopoietic Necrosis Virus NV mutant vaccine" ; rdfs:subClassOf obo:VO_0012165 . obo:VO_0002980 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Mutant influenza virus that lacks the transmembrane and cytoplasmic tail domains of M2 (M2 knockout [M2KO]) from Influenza A virus (A/Puerto Rico/8/34(H1N1)) is attenuated in both cell culture and mice. Mice intranasally vaccinated with M2KO virus developed protective immune responses and survived a lethal challenge with the wild-type virus, suggesting that the M2KO virus has potential as a live attenuated vaccine" ; rdfs:label "Influenza virus CTA1-3M2e-DD protein vaccine" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0002981 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Intranasal inoculation of mice, pigs, horses, and macaques with NS1-modified influenza virus strains induced robust humoral and cellular immune responses, and generated immune protection against challenge with wild-type virus" ; rdfs:label "Influenza virus NS1 mutant vaccine" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0002982 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A mutation in the GP5 protein attenuates HP-PRRSV in piglets. This mutant (HuN4-F112) induces protection against challenge with wild type HP-PRRSV" ; rdfs:label "Porcine respiratory and reproductive syndrome virus GP5 protein mutant vaccine" ; rdfs:subClassOf obo:VO_0001511 . obo:VO_0002983 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002984", "VO:0002988" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV", "A glycoprotein E mutant, in combination with UL23 and glycoprotein G mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV", "A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ; rdfs:label "Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine" ; rdfs:subClassOf obo:VO_0000750 . obo:VO_0002984 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002983 ; a owl:Class ; rdfs:comment "A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ; rdfs:label "obsolete Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002985 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A glycoprotein M, gM, deletion in pseudorabies virus was attenuated and induced protection in piglets against intranasal challenge with 108 p.f.u. of the highly virulent PrV strain NIA-3" ; rdfs:label "Psuedorabies virus glycoprotein M mutant vaccine" ; rdfs:subClassOf obo:VO_0000750 . obo:VO_0002986 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002987" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky's disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3" ; rdfs:label "Pseudorabies virus gp50/gp63 mutant vaccine" ; rdfs:subClassOf obo:VO_0000750 . obo:VO_0002987 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002986 ; a owl:Class ; rdfs:comment "A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated and provided protection from clinical signs of Aujeszky's disease after a challenge inoculation with the virulent wild-type PRV strain NIA-3" ; rdfs:label "obsolete Pseudorabies virus gp50/gp63 mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002988 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002983 ; a owl:Class ; rdfs:comment "A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons, with a 75% survival rate. This mutant also provides some protection from wild type PRV" ; rdfs:label "obsolete Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002989 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A UL50 mutant is attenuated in pseudorabies virus and induces significant protection in pigs from challenge with the highly virulent NIA-3 strain of PrV" ; rdfs:label "Pseudorabies virus UL50 mutant vaccine" ; rdfs:subClassOf obo:VO_0000750 . obo:VO_0002990 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Researchers intranasally inoculated pigs, the natural host of this virus, with mutant PRV strains in which the genes encoding the protein kinase (US3) proteins were inactivated. After challenge infection with the virulent PRV strain NIA-3, no virus was excreted by wt PRV- and PK- mutant-immunized animals, indicating complete protective immunity" ; rdfs:label "Pseudorabies virus US3 mutant vaccine" ; rdfs:subClassOf obo:VO_0000750 . obo:VO_0002991 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A glycoprotein G mutant in rabies virus is attenuated. After a one-dose intramuscular vaccination, the ERAg3m virus protected 100% of mice and hamsters from lethal challenge. In co-infections, using a lethal dose of street rabies virus mixed with ERAg3m, 100% of hamsters and 90% of mice survived and were protected against subsequent infection" ; rdfs:label "Rabies virus glycoprotein G mutant vaccine" ; rdfs:subClassOf obo:VO_0000650 . obo:VO_0002992 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A P gene mutant is attenuated in mice and induces significant protection from challenge with wild type Rabies virus" ; rdfs:label "Rabies virus P protein mutant vaccine" ; rdfs:subClassOf obo:VO_0000650 . obo:VO_0002993 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An E mutant is attenuated in hamsters and induces significant protection from challenge with wild type SARS" ; rdfs:label "SARS-CoV E gene mutant vaccine" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0002994 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A SIV nef mutant is attenuated in rhesus monkeys and induces protection from challenge with wild type SIV" ; rdfs:label "Simian Immunodeficiency Virus nef mutant vaccine" ; rdfs:subClassOf obo:VO_0000751 . obo:VO_0002995 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A virus with a mutation in protein C is attenuated in mice and induced protection from challenge with wild type TBE virus" ; rdfs:label "ick-borne Encephalitis Virus C protein mutant vaccine" ; rdfs:subClassOf obo:VO_0012190 . obo:VO_0002996 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0002997" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE" ; rdfs:label "VEE Virus PE2/E1 mutant vaccine" ; rdfs:subClassOf obo:VO_0001499 . obo:VO_0002997 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0002996 ; a owl:Class ; rdfs:comment "A VEE mutant with a PE2 cleavage signal mutation and a suppressor mutation in E1 is highly attenuated in mice and provides complete protection against challenge with wild type VEE" ; rdfs:label "obsolete VEE Virus PE2/E1 mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0002998 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A virus with a C protein mutation is attenuated in mice and induces significant protection from challenge with wild type West Nile virus" ; rdfs:label "West Nile virus C protein mutant vaccine" ; rdfs:subClassOf obo:VO_0000752 . obo:VO_0002999 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000103 ; obo:IAO_0000233 ; a owl:Class ; rdfs:comment "A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ; rdfs:label "obsolete WEEV DNA Vaccine encoding 6K-E1 Protein" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0003000 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A PE2 mutant combined with a deletion in E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ; rdfs:label "Western equine encephalomyelitis virus PE2/E1 mutant vaccine" ; rdfs:subClassOf obo:VO_0012188 . obo:VO_0003001 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0003002 ; a owl:Class ; rdfs:comment "A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ; rdfs:label "obsolete WEEV Subunit E2 Protein Vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0003002 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0003001" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A PE2 mutant combined with a deletion in E2 (WE2102) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of this strain would occur" ; rdfs:label "Western equine encephalomyelitis virus PE2/E2 mutant virus" ; rdfs:subClassOf obo:VO_0012188 . obo:VO_0003003 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0003004" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur" ; rdfs:label "Western equine encephalomyelitis virus PE2/E1 or E2 mutant vaccine" ; rdfs:subClassOf obo:VO_0012188 . obo:VO_0003004 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0003003 ; a owl:Class ; rdfs:comment "A PE2 mutant combined with either a deletion in E2 (WE2102) or E1 (WE2130) induced low-level viremia in chickens and protected against challenge with wild type WEE after 2 weeks. This study also found that it is unlikely that mosquito transmission of these two strains would occur" ; rdfs:label "obsolete Western equine encephalomyelitis virus PE2/E2 mutant virus" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0003005 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A cen1 mutant is attenuated in mice and hamsters and induces significant protection from challenge with wild type L. donovani" ; rdfs:label "Leishmania donovani cen1 mutant vaccine" ; rdfs:subClassOf obo:VO_0001142 . obo:VO_0003006 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A Leishmania infantum deletion mutant of HSP70-II gene is attenuated and provides protection against Leishmania infection in the L. major-BALB/c infection model. Also, DeltaHSP70-II is a safe live vaccine as immunodeficient SCID mice, and hamsters, infected with mutant parasites did not develp any sign of pathology" ; rdfs:label "Leishmania infantum HSP70 II mutant vaccine" ; rdfs:subClassOf obo:VO_0012159 . obo:VO_0003007 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A genetically attenuated parasite (GAP) with a mutation in the FabB/FabF gene is attenuated in mice by arresting in the late liver stage. It also conferred complete protection in mice from challenge with wild type Plasmodium" ; rdfs:label "Plasmodium FabB/FabF mutant vaccine" ; rdfs:subClassOf obo:VO_0000087 . obo:VO_0003008 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Genetically attenuated P36p-deficient Plasmodium berghei sporozoites provide protection against sporozoites challenge in mice" ; rdfs:label "P. berghei p36p mutant vaccine" ; rdfs:subClassOf obo:VO_0002513 . obo:VO_0003009 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0003010" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites" ; rdfs:label "P. yoelii p36/p52 mutant vaccine" ; rdfs:subClassOf obo:VO_0002514 . obo:VO_0003010 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0003009 ; a owl:Class ; rdfs:comment "A genetically attenuated parasite (GAP) with deletions in p52 and p36 are attenuated in mice. Mice immunized with the mutant were completely protected against challenge with wild type Plasmodium sporozoites" ; rdfs:label "obsolete P. yoelii p36/p52 mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0003011 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Deletion of UIS3 in Plasmodium yoelii provided attenuation and full protection in mice by Pyuis3(-) sporozoites required at least 2 immunizations against challenges with infectious sporozoites" ; rdfs:label "P. yoelii UIS3 mutant vaccine" ; rdfs:subClassOf obo:VO_0002514 . obo:VO_0003012 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A mic2 mutant is attenuated in mice and induces protection from challenge with wild type T. gondii" ; rdfs:label "Toxoplasma gondii mic2 mutant vaccine" ; rdfs:subClassOf obo:VO_0000994 . obo:VO_0003013 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii" ; rdfs:label "Toxoplasma gondii OMPDC mutant vaccine" ; rdfs:subClassOf obo:VO_0000994 . obo:VO_0003014 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:hasAlternativeId "VO:0003015" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A UP mutant, in combination with an OMPDC mutation, is attenuated in mice and induces significant protection from wild type T. gondii", "An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii" ; rdfs:label "Toxoplasma gondii OMPDC/UP mutant vaccine" ; rdfs:subClassOf obo:VO_0000994 . obo:VO_0003015 obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0003014 ; a owl:Class ; rdfs:comment "A UP mutant, in combination with an OMPDC mutation, is attenuated in mice and induces significant protection from wild type T. gondii" ; rdfs:label "obsolete Toxoplasma gondii OMPDC/UP mutant vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0003016 obo:IAO_0000115 "A route of administration that located in the stomach, so that the material is taken into body through stomach directly. " ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intragastric route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0003017 obo:IAO_0000115 "An intragastric route that has a vaccine injection site located in stomach." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intragastric injection route" ; rdfs:subClassOf obo:VO_0003016 . obo:VO_0003018 obo:IAO_0000115 "vaccination that occurs in the intagastric route." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "intragastric vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0003016 ] . obo:VO_0003019 obo:IAO_0000115 "vaccination process that occurs in intradermal route." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "intradermal vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000887 ] . obo:VO_0003020 obo:IAO_0000115 "vaccination process that occurs in intranasal route" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "intranasal vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000341 ] . obo:VO_0003021 obo:IAO_0000115 "vaccination process that occurs in oral route." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "oral vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000886 ] . obo:VO_0003022 obo:IAO_0000115 "vaccination process that occurs in the subcutaneous route" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "subcutaneous vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0000532 ] . obo:VO_0003023 obo:IAO_0000115 "A vaccine prepration process that mixes vaccine lyophilized powder and diluent liquid. The process forms a vaccine that can be used for administration. This term can also be considered as a child term of OBI term 'material combination'. " ; obo:IAO_0000117 "YL, YH" ; obo:IAO_0000119 "WEB: http://www.thehaiticonnection.org/medical/reconstitution.pdf" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:comment """A vaccine may include vaccine powder and solvent. When the two mix, we get a vaccine solution, which can be used to inject. Examples: http://www.medicines.org.uk/guides/acwy%20vax/Vaccinations%20%28all%29/ http://www.medicines.org.uk/guides/menitorix/Vaccinations%20%28all%29/ http://www.medicines.org.uk/guides/priorix/Vaccinations%20%28all%29/ """, "Use only the specific diluent provided by the manufacturer for each type of vaccine to ensure adequate potency and safety of the resulting mixture." ; rdfs:label "vaccine reconstitution" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:OBI_0000652 ] . obo:VO_0003024 obo:IAO_0000115 "a vaccine powder that is freeze-dried and lyophilized. " ; obo:IAO_0000117 "YL,YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "lyophilized vaccine powder" ; rdfs:subClassOf obo:VO_0000228 . obo:VO_0003025 obo:IAO_0000115 "a role inheres in the vaccine component when it is added into vaccine's formulation, it tends to stabilizes an emulsion by increasing its kinetic stablity." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine emulsifier role" ; rdfs:subClassOf obo:VO_0000415 . obo:VO_0003026 obo:IAO_0000115 "a role inheres in vaccine component when added into vaccine's formulation, it tends to inhibit the reaction between two or more other vaccine substances in the final vaccine formulation; it also helps to protect the vaccine from adverse conditions such as the freeze-drying process or heat." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine stabilizer role" ; rdfs:subClassOf obo:VO_0000415 . obo:VO_0003027 obo:IAO_0000115 "a protein vaccine stablizer that is specifically human serum albumin." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "human serum albumin vaccine additive" ; rdfs:subClassOf obo:VO_0003038, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003028 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003026 ] . obo:VO_0003028 obo:IAO_0000115 "the serum albumin that is part of human" ; obo:IAO_0000116 "it is subclass of 'serum albumin (PR:000003918)'" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "human serum albumin" ; rdfs:seeAlso "UniProtKB:P02768" ; rdfs:subClassOf obo:VO_0000516 . obo:VO_0003029 obo:IAO_0000115 "a vaccine stabilizer that is gelatin." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "gelatin vaccine stabilizer" ; rdfs:subClassOf obo:VO_0000853, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003030 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003026 ] . obo:VO_0003030 obo:IAO_0000115 "Gelatin is a mixture of peptides and proteins produced by partial hydrolysis of collagen extracted from the skin, boiled crushed bones, connective tissues, organs and some intestines of animals such as domesticated cattle, chicken, and pigs.(wikipedia)" ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "material entity" ; a owl:Class ; rdfs:label "gelatin" ; rdfs:subClassOf obo:BFO_0000040 . obo:VO_0003031 obo:IAO_0000115 "a vaccine-induced host gene response that represents a vaccine adverse event response associated with a host susceptibility gene." ; obo:IAO_0000117 "YH" ; obo:IAO_0000118 "host susceptibility gene response to VAE" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "host susceptibility gene response to vaccine adverse event" ; rdfs:subClassOf obo:VO_0000286 . obo:VO_0003032 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "host immune factor-induced control of intracellular replication of live attenuated vaccine" ; rdfs:subClassOf obo:VO_0000286 . obo:VO_0003033 obo:IAO_0000115 "a protein vaccine stablizer that is specifically bovine serum albumin. " ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "bovine serum albumin vaccine additive" ; rdfs:subClassOf obo:VO_0003038 . obo:VO_0003034 obo:IAO_0000115 "a vaccine stabilizer that is specifically made by a sugar." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "sugar vaccine stabilizer" ; rdfs:subClassOf obo:VO_0000853 . obo:VO_0003035 obo:IAO_0000115 "a vaccine stabilizer that is generated based on amino acids. " ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "amino acid vaccine stabilizer" ; rdfs:subClassOf obo:VO_0000853 . obo:VO_0003036 obo:IAO_0000115 "a vaccine stabilizer that is specifically made by a sucrose. " ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "sucrose vaccine stabilizer" ; rdfs:subClassOf obo:VO_0003034 . obo:VO_0003037 obo:IAO_0000115 "a vaccine stabilizer that is specifically made by a lactose." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "lactose vaccine stabilizer" ; rdfs:subClassOf obo:VO_0003034 . obo:VO_0003038 obo:IAO_0000115 "a vaccine stabilizer that is a protein." ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "protein vaccine stabilizer" ; rdfs:subClassOf obo:VO_0000853 . obo:VO_0003039 obo:IAO_0000115 "a polysorbate 20 vaccine stabilizer that is Alkest TW20. " ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Alkest TW 20 vaccine stabilizer" ; rdfs:subClassOf obo:VO_0000929 . obo:VO_0003040 obo:IAO_0000115 "a polysorbate 20 vaccine stabilizer that is Tween 20. " ; obo:IAO_0000117 "YH, YL" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Tween 20 vaccine stabilizer" ; rdfs:subClassOf obo:VO_0000929 . obo:VO_0003041 obo:IAO_0000115 "an antibiotics vaccine residual that has the antibiotics of neomycin. " ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "neomycin residual" ; rdfs:subClassOf obo:VO_0000704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_7507 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000704 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_7507 ] ) ] . obo:VO_0003042 obo:IAO_0000115 "the vaccine antiegn that induces protective immune response. " ; obo:IAO_0000117 "YL, YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "protective vaccine antigen" ; rdfs:subClassOf obo:VO_0000919, obo:VO_0001232, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000919 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] ) ] . obo:VO_0003043 obo:IAO_0000115 "A viral vaccine against infection of an Sindbis virus." ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Sindbis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11034 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11034 ] . obo:VO_0003044 obo:IAO_0000115 "A viral vaccine against infection of a Lymphocytic choriomeningitis virus." ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lymphocytic choriomeningitis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052303 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052303 ] . obo:VO_0003045 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "RB51 induced protection against B.suis" ; rdfs:subClassOf obo:VO_0003086, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:NCBITaxon_29461 ] . obo:VO_0003046 obo:IAO_0000115 "A protozoan vaccine against Schistosoma mansoni" ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Schistosoma mansoni vaccine" ; rdfs:subClassOf obo:VO_0003047, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5866 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5866 ] . obo:VO_0003047 obo:IAO_0000115 "A protozoan vaccine against Schistosoma infection" ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Schistosoma vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6181 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6181 ] . obo:VO_0003048 obo:IAO_0000115 "when the vaccination of a significant portion of a population (or herd), in contagious diseases that are transmitted from individual to individual, chains of infection are likely to be disrupted, so the large numbers of a population are immue or less susceptible to the disease. " ; obo:IAO_0000117 "YL" ; obo:IAO_0000119 "http://en.wikipedia.org/wiki/Herd_immunity" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine-induced herd immunity" ; rdfs:subClassOf obo:VO_0000288 . obo:VO_0003049 obo:IAO_0000115 "The conjugate protein is a part of a conjugate vaccine and acts as a carrier protein that is covalently attached to a vaccine antigen with poor antigenicity (e.g., a polysaccharide). A conjugate protein is able to induce T-cell-dependent immune responses and stimulate the production of immune memory." ; obo:IAO_0000117 "YL,YH" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "vaccine conjugate protein" ; rdfs:subClassOf obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000179 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003050 ] ) ] . obo:VO_0003050 obo:IAO_0000115 "role inheres in a material eneitity that union itself chemically with a relative weak vaccine antigen to form a new whole that can create an effective miinuogen. The " ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "vaccine conjugate role" ; rdfs:subClassOf obo:VO_0000617 . obo:VO_0003051 obo:IAO_0000117 "YL" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:comment "epicutaneous (application onto the skin)" ; rdfs:label "percutaneous route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0003052 obo:IAO_0000115 "Administration of a drug by the way of absorption through the skin, usually for systemic action. The route allows sustained therapeutic plasma drug levels and avoids first pass effect. Simplicity of administration tends to result in high patient compliance.|YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "percutaneous vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0003051 ] . obo:VO_0003053 oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "intravesical route" ; rdfs:subClassOf obo:VO_0000574 . obo:VO_0003054 obo:IAO_0000115 "The injection of a given substance directly into the bladder via a urethral catheter instead of being injected under the skin." ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "intravesical vaccination" ; rdfs:subClassOf obo:VO_0000002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:VO_0003053 ] . obo:VO_0003055 obo:IAO_0000115 "A viral vaccine against infection of an infectious pancreatic necrosis virus." ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infectious pancreatic necrosis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11002 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11002 ] . obo:VO_0003056 obo:IAO_0000115 "A viral vaccine against infection of a viral haemorrhagic septicaemia virus." ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "viral haemorrhagic septicaemia virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11287 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11287 ] . obo:VO_0003057 obo:IAO_0000115 "an vaccine-induced host response that shows augmented protection and cellular immunity after a host protein is used as adjuvant. " ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "augmented protection and cellular immunity using host protein as adjuvant" ; rdfs:subClassOf obo:VO_0000288 . obo:VO_0003058 obo:IAO_0000115 "A vaccine that protects against Mycobacterium marinum." ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycobacterium marinum vaccine" ; rdfs:subClassOf obo:VO_0000592 . obo:VO_0003059 obo:IAO_0000115 "A viral vaccine that protects against infection with Hepatitis D virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis D virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12475 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12475 ] . obo:VO_0003060 obo:IAO_0000115 "viral vaccine that is used to protect against Monkeypox virus infection" ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Monkeypox virus vaccine" ; rdfs:subClassOf obo:VO_0000512, obo:VO_0003539, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10244 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10244 ] . obo:VO_0003061 obo:IAO_0000115 "viral vaccine that is used to protect against Bovine viral diarrhea virus 2 infection" ; obo:IAO_0000117 "YH, RS" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine viral diarrhea virus 2 vaccine" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_54315 ] . obo:VO_0003062 obo:IAO_0000115 "A viral vaccine that protects against infection with Murine Cytomegalovirus (or called murid herpesvirus 1)." ; obo:IAO_0000117 "YH, RS, NF" ; obo:IAO_0000118 "murine cytomegalovirus vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Murid herpesvirus 1 vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10366 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10366 ] . obo:VO_0003063 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "RB51 induced protection against B.abortus" ; rdfs:subClassOf obo:VO_0003086, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:NCBITaxon_235 ] . obo:VO_0003064 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "RB51 induced protection against B.canis" ; rdfs:subClassOf obo:VO_0003086, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:NCBITaxon_36855 ] . obo:VO_0003065 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "RB51 induced protection against B.Melitensis" ; rdfs:subClassOf obo:VO_0003086, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:NCBITaxon_29459 ] . obo:VO_0003066 obo:IAO_0000117 "Kallan Roan, Oliver He, OT" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601403", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm431374.htm", "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM431447.pdf" ; obo:VO_0003099 "BEXSERO" ; obo:VO_0003158 "Meningococcal Group B Vaccine" ; obo:VO_0003160 "Active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B in individuals 10 through 25 years of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM431447.pdf" ; obo:VO_0003162 "BL 125546" ; obo:VO_0003198 "1601403" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bexsero" ; rdfs:seeAlso "CVX: 163", "VIOLIN Vaccine ID: 5576" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000534, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003347 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003360 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003362 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003364 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000696 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003067 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000119 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM524684.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Flublok Quadrivalent" ; rdfs:label "Flublok Quadrivalent" ; rdfs:seeAlso "CVX: 155", "VIOLIN Vaccine ID: 5556" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003069 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003068 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "RB51 induced host immune response" ; rdfs:subClassOf obo:VO_0000287, [ a owl:Restriction ; owl:onProperty obo:VO_0000462 ; owl:someValuesFrom obo:VO_0000021 ] . obo:VO_0003069 obo:IAO_0000119 "http://www.proteinsciences.com/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Protein Sciences Corporation" . obo:VO_0003070 obo:IAO_0000117 "OT, YH." ; obo:IAO_0000119 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM502899.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Flucelvax Quadrivalent" ; rdfs:label "Flucelvax Quadrivalent" ; rdfs:seeAlso "CVX: 171", "VIOLIN Vaccine ID: 5561" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000689 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003071 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm366061.htm", "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM404086.pdf" ; obo:VO_0003099 "FluLaval" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003159 "ID Biomedical Corporation of Quebec" ; obo:VO_0003160 "For active immunization of persons 6 months of age and older for the prevention of disease caused by influenza A subtype viruses and type B viruses contained in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM619548.pdf" ; obo:VO_0003162 "BL 125163" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FluLaval Quadrivalent" ; rdfs:seeAlso "CVX: 158", "VIOLIN Vaccine ID: 5562" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003072 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000119 "http://ca.gsk.com/media/590283/flulaval-tetra.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Quadrivalent Influenza Vaccine (Split Virion, Inactivated)", "Trade Name: FluLaval Tetra" ; rdfs:label "FluLaval Tetra" ; rdfs:seeAlso "VIOLIN Vaccine ID: 5563" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003073 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm356091.htm" ; obo:VO_0003099 "Fluzone Quadrivalent" ; obo:VO_0003158 "Influenza Virus Vaccine" ; obo:VO_0003160 "For active immunization of persons 6 months of age and older for the prevention of influenza disease caused by influenza A subtype viruses and type B viruses contained in the vaccine." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM356094.pdf" ; obo:VO_0003162 "BL 103914" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluzone Quadrivalent" ; rdfs:seeAlso "CVX: 158", "VIOLIN Vaccine ID: 5566" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003074 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000119 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM513242.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Influenza Virus Vaccine", "Trade Name: Fluzone Quadrivalent Southern Hemisphere" ; rdfs:label "Fluzone Quadrivalent - Southern Hemisphere Formulation" ; rdfs:seeAlso "CVX: 158", "VIOLIN Vaccine ID: 5568" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197911 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197912 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003075 obo:IAO_0000117 "Kallan Roan, Oliver He, Omar Tibi, Khadeejah Khan" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1597095", "https://www.cancer.org/latest-news/fda-approves-gardasil-9-hpv-vaccine.html", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm426445.htm" ; obo:VO_0003099 "Gardasil 9" ; obo:VO_0003158 "Human Papillomavirus 9-valent Vaccine, Recombinant" ; obo:VO_0003160 """Indicated in girls and women 9 through 45 years of age for the prevention of the following diseases: - Cervical, vulvar, vaginal, and anal cancer caused by Human Papillomavirus (HPV) types 16, 18, 31, 33, 45, 52, and 58. (1.1) Genital warts (condyloma acuminata) caused by HPV types 6 and 11. (1.1) And the following precancerous or dysplastic lesions caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58: - Cervical intraepithelial neoplasia (CIN) grade 2/3 and cervical adenocarcinoma in situ (AIS). (1.1) - Cervical intraepithelial neoplasia (CIN) grade 1. (1.1) - Vulvar intraepithelial neoplasia (VIN) grade 2 and grade 3. (1.1) - Vaginal intraepithelial neoplasia (VaIN) grade 2 and grade 3. (1.1) - Anal intraepithelial neoplasia (AIN) grades 1, 2, and 3. (1.1) GARDASIL 9 is indicated in boys and men 9 through 45 years of age for the prevention of the following diseases: - Anal cancer caused by HPV types 16, 18, 31, 33, 45, 52, and 58. (1.2) - Genital warts (condyloma acuminata) caused by HPV types 6 and 11. (1.2) And the following precancerous or dysplastic lesions caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58: - Anal intraepithelial neoplasia (AIN) grades 1, 2, and 3. (1.2)""" ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM426457.pdf" ; obo:VO_0003162 "125508" ; obo:VO_0003198 "1597095" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Gardasil 9" ; rdfs:seeAlso "CVX: 165", "VIOLIN Vaccine ID: 5546" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0000667, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003300 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003301 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003302 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003303 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003304 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003305 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003306 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003307 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003308 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003076 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Valneva SE" . obo:VO_0003077 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "RB51 induced protection against B. ovis" ; rdfs:subClassOf obo:VO_0003086, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:NCBITaxon_236 ] . obo:VO_0003078 obo:IAO_0000115 "An Israeli research and development laboratory" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Israel_Institute_for_Biological_Research" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Israel Institute for Biological Research" . obo:VO_0003079 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "PaxVax, Inc." . obo:VO_0003080 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000119 "http://www.pfizer.ca/sites/g/files/g10028126/f/201604/Nimenrix_PM_184020_23Mar2016_E.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Nimenrix" ; rdfs:seeAlso "VIOLIN Vaccine ID: 5578" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000195, obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003081 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593136", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm421020.htm" ; obo:VO_0003099 "TRUMENBA" ; obo:VO_0003158 "Meningococcal Group B Vaccine" ; obo:VO_0003160 "Indicated for active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. Trumenba is approved for use in individuals 10 through 25 years of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM421139.pdf" ; obo:VO_0003162 "BL 125549" ; obo:VO_0003198 "1593136" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trumenba" ; rdfs:seeAlso "CVX: 162", "VIOLIN Vaccine ID: 5577" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000534, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003366 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003368 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003082 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1812946", "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM506235.pdf" ; obo:VO_0003198 "1812946" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaxchora" ; rdfs:seeAlso "CVX: 174", "VIOLIN Vaccine ID: 5569" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000763, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003955 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003079 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003083 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000118 "H5N1 vaccine GSK" ; obo:IAO_0000119 "https://www.fda.gov/downloads/BiologicsBloodVaccines/SafetyAvailability/VaccineSafety/UCM376464.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted" ; rdfs:label "Influenza A (H5N1) Virus Monovalent Vaccine, Adjuvanted by GSK" ; rdfs:seeAlso "CVX: 160", "VIOLIN Vaccine ID: 5553" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_102793 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003084 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000118 "H1N1 vaccine GSK" ; obo:IAO_0000119 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM190377.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Product Name: Influenza A (H1N1) 2009 Monovalent Vaccine" ; rdfs:label "Influenza A (H1N1) 2009 Monovalent Vaccine (GlaxoSmithKline)" ; rdfs:seeAlso "VIOLIN Vaccine ID: 5552" ; rdfs:subClassOf obo:VO_0001176, obo:VO_0001485, obo:VO_0003143, obo:VO_0003211, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003085 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000119 "https://www.vaccineshoppecanada.com/document.cfm?file=adacel-polio_e.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Adacel-Polio" ; rdfs:label "Adacel-Polio" ; rdfs:seeAlso "VIOLIN Vaccine ID: 5549" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000742, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_17076 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000917 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003086 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "RB51 induced immune protection" ; rdfs:subClassOf obo:VO_0003068 . obo:VO_0003087 oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "RB51 induced immune response without protection" ; rdfs:subClassOf obo:VO_0003068 . obo:VO_0003088 obo:IAO_0000117 "OT, YH" ; obo:IAO_0000119 "https://ca.gsk.com/media/589683/boostrix-polio.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Boostrix-Polio" ; rdfs:label "Boostrix-Polio" ; rdfs:seeAlso "VIOLIN Vaccine ID: 5550" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000742, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000917 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003089 a obo:VO_0000299, owl:NamedIndividual ; rdfs:comment "Out of buisness" ; rdfs:label "Lederle Laboratories Division" . obo:VO_0003090 obo:IAO_0000115 "This vaccine is given to provide protection against diphtheria, tetanus, and pertussis in children between 6 weeks and 7 years old." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.drugs.com/mmx/tri-immunol.html", "https://www.hendricks.org/HealthLibrary/default.aspx?sid=1&pTitle=%2CDrug&ContentTypeID=26&ContentID=215&alpha=T&AdditionalTitle=Tri-Immunol" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "discontinued now" ; rdfs:label "Tri-Immunol" ; rdfs:subClassOf obo:VO_0000738, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003089 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003091 obo:IAO_0000115 "Influenza virus vaccine is used to prevent infection caused by influenza virus types A and B." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.drugs.com/mtm/fluogen-injectable.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluogen" ; rdfs:subClassOf obo:VO_0002497, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003125 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003092 obo:IAO_0000115 "monovalent vaccine agianst poliomyelitis for infants 6-12 weeks of age, all immunized children up to 18 years of age, and high risk adults." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.rxlist.com/orimune-drug.htm" ; obo:VO_0003158 "Oral Poliovirus Vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Orimune vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0003167, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003089 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003093 obo:IAO_0000115 "A malaria vaccine that consists of hepatitis B surface antigen virus-like particles, incorporating a portion of the Plasmodium falciparum-derived circumsporozoite protein and a liposome-based adjuvant." ; obo:IAO_0000117 "YH, Randi Vita" ; obo:IAO_0000119 "PMID:20078211", "https://en.wikipedia.org/wiki/RTS,S", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829262/" ; obo:VO_0003099 "Mosquirix" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "In July 2015, RTS,S/AS01 was approved by the European Medicines Agency for immunization of children aged 6 weeks to 17 months against malaria under Article 58,12." ; rdfs:label "P. falciparum RTS,S/AS01" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000464 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:VO_0011218 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000137 ] . obo:VO_0003094 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pnu-Imune vaccine" ; rdfs:subClassOf obo:VO_0000165, obo:VO_0000367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ] . obo:VO_0003095 obo:IAO_0000115 "Revaxis is a Diphtheria, Tetanus and Poliomyelitis (inactivated) vaccine manufactured by Sanofi Pasteur. This vaccine helps boost protection against diphtheria, tetanus and poliomyelitis (polio)." ; obo:IAO_0000118 "3-in-1 diphtheria, polio and tetanus vaccine (Revaxis)" ; obo:IAO_0000119 "http://www.netdoctor.co.uk/medicines/infections/a8594/revaxis-diphtheria-polio-and-tetanus-vaccine/", "https://www.medicines.org.uk/emc/files/pil.5581.pdf", "https://www.medicines.org.uk/emc/product/5581/smpc", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166496/" ; obo:VO_0003147 """Dose: 0.5-mL suspension for injection in a pre-filled syringe Active ingredients: Purified diphtheria toxoid ‚â•2 IU (5 Lf) Purified tetanus toxoid ‚â•20 IU (10 Lf) Inactivated poliovirus type 1 40 DU Inactivated poliovirus type 2 8 DU Inactivated poliovirus type 3 32 DU Adsorbant: Aluminum hydroxide. 0.35 mg (as aluminum)""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Revaxis is used for preventing diphtheria, tetanus and polio in children from six years of age, adolescents and adults. Revaxis is used for a booster vaccination against these diseases. It is given to teenagers at 14 years of age as part of the British childhood immunisation schedule." ; rdfs:label "Revaxis" ; rdfs:subClassOf obo:VO_0000943, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003096 obo:IAO_0000115 "a Diphthpheria-Tetanus Absorbed vaccine for children 7 years of age and adults." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://drug-info.in/ditanrix-diphtheria-tetanus-vaccine-adsorbed-glaxosmithkline" ; obo:VO_0003158 "TD Absorbed and DT Absorbed Vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ditanrix" ; rdfs:subClassOf obo:VO_0000732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001145 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003097 obo:IAO_0000115 "A rotavirus vaccine against severe diarrheal disease." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://web.stanford.edu/~siegelr/ShadmanRotashieldPaper.pdf" ; obo:VO_0003147 "Amphotericin B, Monosodium Glutamate (MSG), Sucrose, Bovine (cow) serum, Potassium Phosphate, Potassium monophosphate." ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "discontinued in 2008" ; rdfs:label "Rotashield vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64220 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003098 obo:IAO_0000115 "A more attenuated measles vaccine that targets measles virus strain Moraten." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://apps.who.int/iris/bitstream/handle/10665/266590/PMC2554544.pdf?sequence=1&isAllowed=y", "https://jamanetwork.com/journals/jama/article-abstract/341314" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Developed sometime in 1968 therefore assumed to be discontinued" ; rdfs:label "Moraten vaccine" ; rdfs:subClassOf obo:VO_0000362, obo:VO_0000367, obo:VO_0000654, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000194 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003099 obo:IAO_0000115 "An annotation property that represents the trade name of a product." ; obo:IAO_0000117 "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "trade name" . obo:VO_0003100 obo:IAO_0000115 "An inactIve vaccine used to prevent tetanus." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://www.catalog.md/drugs/tevax.html", "https://www.atoute.org/n/IMG/pdf/Constituants_des_vaccins_version-actualisee.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Discontinued in 2003" ; rdfs:label "Tevax vaccine" ; rdfs:subClassOf obo:VO_0000640, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003101 obo:IAO_0000115 "An active immunization against cholera, indicated only for individuals traveling to or residing in countries where cholera is endemic or epidemic." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.rxlist.com/cholera-vaccine-drug.htm#indications" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Cholera Vaccine, USP" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000763, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:VO_0001187 obo:VO_0003019 obo:VO_0003022 ) ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003102 obo:IAO_0000115 "a hexavalent vaccine that has been withrawn on June 2012 by the European commission" ; obo:IAO_0000118 "Hexavac Vaccine" ; obo:IAO_0000119 "http://www.ema.europa.eu/docs/en_GB/document_library/Public_statement/2012/08/WC500130968.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hexavax" ; rdfs:subClassOf obo:VO_0000195, obo:VO_0000484, obo:VO_0000738, obo:VO_0000746, obo:VO_0001214, obo:VO_0010718, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000703 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003103 obo:IAO_0000115 "A vaccine used to help prevent rabies infection in people who either have been, or are at risk of being bitten, licked or scratched by an animal infected with rabies virus." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://www.who.int/immunization_standards/vaccine_quality/Rabipur_Product_Insert.pdf" ; obo:VO_0003147 "Amphotericin B, Neomycin, Sucrose, Chlortetracycline hydrochloride, Sodium chloride, Bovine (cow) serum, Trometamol, Polygeline, Virus: Rabies, Disodium edentate (EDTA), Monopotassium glutamate" ; obo:VO_0003158 "Rabies Virus Vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabipur vaccine" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64220 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000696 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003104 obo:IAO_0000119 "https://www.ndrugs.com/?s=rabiesvax" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabiesvax vaccine" ; rdfs:subClassOf obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] . obo:VO_0003105 obo:IAO_0000115 "LYMErix [Lyme Disease Vaccine (Recombinant OspA)] is a noninfectious recombinant vaccine developed and manufactured by SmithKline Beecham Biologicals. The vaccine contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus." ; obo:IAO_0000116 "Discontinued in 2002" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "lipoprotein outer surface a vaccine" ; obo:IAO_0000119 "https://wayback.archive-it.org/7993/20170405164754/https://www.fda.gov/ohrms/dockets/ac/01/briefing/3680b2_03.pdf", "https://www.rxlist.com/lymerix-drug.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lymerix" ; rdfs:subClassOf obo:VO_0004028, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000145 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003106 obo:IAO_0000118 "DTP vaccine", "DTwP vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria, tetanus and whole cell pertussis vaccine" ; rdfs:subClassOf obo:VO_0000738, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003107 obo:IAO_0000115 "A human diploid cell vaccine against rabies, a viral infectious disease." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.researchgate.net/publication/27190851_Vaccination_against_rabies_and_protective_antibodies_-_Comparison_of_ELISA_and_fluorescent_antibody_virus_neutralization_FAVN_assays" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabivac" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003108 obo:IAO_0000115 "This absorbed recombinant hepatitis B vaccine is indicated for active immunization against hepatitis B virus infection caused by all known subtypes in subjects of any age considered at risk of exposure to the virus." ; obo:IAO_0000118 "Genhevac B Pasteur" ; obo:IAO_0000119 "https://www.mesvaccins.net/web/vaccines/48-genhevac-b-pasteur", "https://www.ncbi.nlm.nih.gov/pubmed/8106774" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Discontinued in 2016", "Kallan Roan, Oliver He" ; rdfs:label "Genhevac B" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000703 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003109 obo:IAO_0000115 "HPV77/DE5 strain" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://americanhistory.si.edu/collections/search/object/nmah_733733" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Older version of Meruvax II" ; rdfs:label "Meruvax I" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0001485, obo:VO_0010637, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003110 obo:IAO_0000115 "A vaccine for indivuduals who at risk or recently exposed to rabies." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://onlinelibrary.wiley.com/doi/pdf/10.1002/0471704210.app4", "https://www.redalyc.org/html/579/57912962006/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabie-Vax" ; rdfs:subClassOf obo:VO_0000650, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003111 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "A vaccine for individuals to protect against mumps virus.", "https://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/cps-_monographs/CPS-_(General_Monographs-_M)/MUMPSVAX.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mumpsvax II" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000656, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003112 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "A live RA 27/3 strain rubella vaccine", "http://www.meppo.com/pdf/drugs/1538-RUDIVAX-1321626694.pdf", "https://www.ncbi.nlm.nih.gov/pubmed/6531969" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rudivax" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0010637, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000703 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003113 obo:IAO_0000115 "An adsorbed diphtheria, tetanus, pertussis and inactivated poliomyelitis vaccine." ; obo:IAO_0000119 "https://www.mesvaccins.net/web/vaccines/63-tetracoq", "https://www.researchgate.net/publication/289445706_Efficacy_and_safety_of_Tetracoq_vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "European/French vaccine", "Often administered with a HIB vaccine." ; rdfs:label "Tetracoq" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000640, obo:VO_0000664, obo:VO_0000712, obo:VO_0000735, obo:VO_0000765, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1513 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1717 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003114 obo:IAO_0000115 "A vaccine for Diphtheria, haemophilus influenzae, pertussis, and tetanus diseases." ; obo:IAO_0000119 "https://www.drugs.com/mtm/trihibit.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Discontinued in 2011" ; rdfs:label "Trihibit" ; rdfs:subClassOf obo:VO_0003168, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003115 obo:IAO_0000115 "A vaccine against flu (influenza) in adults, especially in those who run an increased risk of experiencing associated complications in case they fall ill with flu." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.medicines.org.uk/emc/files/pil.6163.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Seasonal", "The vaccine targets three strains of influenza virus, and is free of chicken/egg protein." ; rdfs:label "Optaflu" ; rdfs:subClassOf obo:VO_0002496, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003164 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003116 obo:IAO_0000115 "A vaccine used to prevent diphtheria and tetanus in individuals over 6 years of age." ; obo:IAO_0000119 "http://www.catalog.md/drugs/td-rix.html", "https://www.impfkritik.de/upload/pdf/fachinfo/Td-Rix-GSK-2006-07.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "European/German vaccine" ; rdfs:label "TD-Rix" ; rdfs:subClassOf obo:VO_0000732, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003117 obo:IAO_0000115 "A combined live virus vaccine used to prevent measles, mumps, and rubella." ; obo:IAO_0000119 "http://vacvine.com/Vaccines/Details/319" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "need better source" ; rdfs:label "Virivac" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000731, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0000069 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003118 obo:IAO_0000115 "A vaccine used to protect against measles, mumps, and rubella for 12-15 month-old individuals." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/18400341" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M-M-R I" ; rdfs:subClassOf obo:VO_0000731, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003119 obo:IAO_0000115 "Active immunization against Haemophilius influenzae type b in recommended routinely for children at 24 months of age and for children at 15 months of age enrolled in child care facilities." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "HIBIMUNE" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745871/", "https://www.ndrugs.com/?s=hib-imune" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Discontinued in 1988" ; rdfs:label "Hib-Imune" ; rdfs:subClassOf obo:VO_0000195, obo:VO_0000627, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003089 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003120 obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000118 "MVA expressing antigen 85A", "modified vaccinia virus Ankara expressing antigen 85A" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/15502839" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA85A" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:VO_0010936 ] . obo:VO_0003121 obo:IAO_0000115 "A Haemophilus influenzae type B conjugate vaccine manufactured by GSB." ; obo:IAO_0000119 "https://www.drugs.com/mtm/omnihib.html", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745871/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Discontinued Vaccine" ; rdfs:label "OmniHIB" ; rdfs:subClassOf obo:VO_0000195, obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003122 obo:IAO_0000115 "A vaccine against diphtheria, tetanus, and pertussis." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.rxlist.com/certiva-drug.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Certiva" ; rdfs:subClassOf obo:VO_0000738, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003123 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003123 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Abbot Laboratories" . obo:VO_0003124 a owl:Class ; rdfs:label "obsolete Fluogen" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0003125 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Parke, Davis, Company" . obo:VO_0003126 obo:IAO_0000115 "A TB vaccine that uses attenuated fowlpox strain FP9 to express mycobacterial mycolyl transferase Ag85A." ; obo:IAO_0000117 "YH" ; obo:IAO_0000119 "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=172", "https://www.ncbi.nlm.nih.gov/pubmed/15196215" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FP85A" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0003127 obo:IAO_0000115 "An object property that represents a relation between a vaccine with a prime-boost schedule and a vaccine used for priming." ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has prime vaccine" . obo:VO_0003128 obo:IAO_0000115 "An object property that represents a relation between a vaccine with a prime-boost schedule and a vaccine used for boost." ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:domain obo:VO_0000001 ; rdfs:label "has boost vaccine" ; rdfs:range obo:VO_0000001 . obo:VO_0003129 obo:IAO_0000115 "Pharmacotherapeutic group (ATC code): J 07 AN 01." ; obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000119 "http://www.immune.org.nz/vaccines/available-vaccines/bcg-vaccine-ssi", "https://www.hse.ie/eng/health/immunisation/hcpinfo/vaccineordering/bcgpil14.pdf" ; obo:VO_0003146 "Freeze-dried powder containing live attenuated bacteria of the type Mycobacterium bovis BCG, Danish strain 1331." ; obo:VO_0003147 "Sodium glutamate, magnesium sulphate heptahydrate, dipotassium phosphate, l-asparagine monohydrate, ferric ammonium citrate, glycerol 85%, citric acid, monohydrate and water for injections" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Mycobacterium bovis BCG (Bacillus Calmette-Gu√©rin), Danish strain 1331, live attenuated, 2‚Äì8 √ó 10^5 CFU per dose." ; rdfs:label "BCG Vaccine SSI" ; rdfs:subClassOf obo:VO_0000771, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ] . obo:VO_0003130 obo:IAO_0000115 "A TB vaccine that uses BCG as vaccine vector." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant BCG vaccine" ; rdfs:subClassOf obo:VO_0000077, obo:VO_0001217, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001014 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0000771 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0000771 ] . obo:VO_0003131 obo:IAO_0000115 "A TB vaccine that recombinant BCG strain with the replacment of its urease C encoding gene with the listeriolysin encoding gene from Listeria monocytogenes." ; obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000118 "BCGΔureC::hly" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610719/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VPM1002" ; rdfs:subClassOf obo:VO_0000603, [ a owl:Restriction ; owl:hasValue obo:VO_0003132 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003132 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Max Planck Institute for Infection Biology" . obo:VO_0003133 obo:IAO_0000115 "The MRK adenovirus type 5 human immunodeficiency virus type 1 clade B gag/pol/nef vaccine is a replication-incompetent adenovirus type 5-vectored vaccine that elicits cell-mediated immunity against conserved human immunodeficiency virus proteins." ; obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000119 "PMID: 18433307", "https://www.ncbi.nlm.nih.gov/pubmed/18433307" ; obo:VO_0003146 "equal parts of 3 recombinant Ad5 vectors: MRKAd5gag, MRKAd5pol, and MRKAd5nef. E1 region of the Ad5 vector was deleted, which rendered the virus incapable of growing in human cells, and was replaced with a transgene construct that consisted of the human cytomegalovirus promoter; the HIV-1 clade B gag, pol, or nef open reading frame; and the bovine growth hormone poly A" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MRKAd5 HIV-1 gag/pol/nef" ; rdfs:subClassOf obo:VO_0000295 . obo:VO_0003134 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A Yellow fever virus vaccine that uses the live attenated 17D strain." ; rdfs:label "YF-17D vaccine" ; rdfs:subClassOf obo:VO_0000123, obo:VO_0000367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003135 obo:IAO_0000115 "A Yellow fever virus vaccine that uses the live attenated 17DD strain." ; obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903908/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Two distinct strains of live attenuated yellow fever virus vaccine, 17D and 17DD, have been widely used. They have the same origin, from a yellow fever virus isolated from a patient with non fatal yellow fever named Asibi, from Ghana, in 1927. The 17D strain, used for vaccine production, corresponds to passage level 235‚Äì240 and the 17DD to a passage level 286‚Äì287. The comparison of the nucleotide sequences of all 17D vaccines showed an overall homology of 99.2%." ; rdfs:label "YF-17DD vaccine" ; rdfs:subClassOf obo:VO_0000123, obo:VO_0000367, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003136 obo:IAO_0000115 "A YF-17DD vaccine t hat is manufactured by Bio-Manguinhos" ; obo:IAO_0000117 "Oliver He, Randi Vita" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "YF 17DD-YFV" ; rdfs:subClassOf obo:VO_0003135, [ a owl:Restriction ; owl:hasValue obo:VO_0003137 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003137 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Bio-Manguinhos" . obo:VO_0003138 obo:IAO_0000115 "a licensed N. meningitidis vaccine that includes meningococcal polysaccharides from Groups A, C, Y and W-135 combined, and is manufactured by GSK." ; obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000118 "ACWYVax" ; obo:IAO_0000119 "http://www.mhra.gov.uk/home/groups/comms-ic/documents/drugsafetymessage/con425089.pdf" ; obo:VO_0003146 "Meningococcal polysaccharides (groups A, C, W135 and Y polysaccharides)" ; obo:VO_0003147 "Lactose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ACWY Vax" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001256 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003139 obo:IAO_0000115 "It is live attenuated YFV vaccine strain 17D manufactured in China, France, Senegal, and the USA. In powder and solvent for suspension for injection in pre-filled syringe." ; obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000118 "17D-204" ; obo:IAO_0000119 "https://www.medicines.org.uk/emc/product/1683/smpc" ; obo:VO_0003146 "Yellow fever virus (produced in specified pathogen-free chick embryos), 17D strain (live, attenuated): not less than 1000 IU" ; obo:VO_0003147 "Lactose, sorbitol, L-histidine hydrochloride, L-alanine, sodium chloride, potassium chloride, sodium phosphate-dibasic dihydrate, potassium phosphate-monobasic, calcium chloride, magnesium sulfate and water for injections." ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Stamaril" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0003134, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003140 obo:IAO_0000115 "A cancer vaccine against non-small cell lung cancer (NSCLC)" ; obo:IAO_0000118 "NSCLC vaccine" ; a owl:Class ; rdfs:label "non-small cell lung cancer vaccine" ; rdfs:subClassOf obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3908 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3908 ] . obo:VO_0003141 obo:IAO_0000115 "A non-small cell lung cancer mRNA-derived vaccine that contains modified mRNAs encoding cancer-testis antigen NY-ESO-1, melanoma-associated antigens C1 (MAGE-C1/CT7) and C2 (MAGE-C2/CT10), survivin, and the oncofetal antigen 5T4 with potential antitumor and immunomodulatory activities." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000119 "https://www.cancer.gov/publications/dictionaries/cancer-drug/def/non-small-cell-lung-cancer-mrna-derived-vaccine-cv9201" ; a owl:Class ; rdfs:label "CV9201" ; rdfs:subClassOf obo:VO_0003140, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3908 ] . obo:VO_0003142 obo:IAO_0000115 "A vaccine role that indicates a clinical trial status of a vaccine" ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "clinical trial vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0003143 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "licensed influenza vaccine" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000642 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000630 ] ) ] . obo:VO_0003144 obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000119 "https://www.medicines.org.uk/emc/product/6355/smpc" ; obo:VO_0003146 "influenza vaccine (surface antigen, inactivated): (haemagglutinin and neuraminidase) of the following strains*: (A/Singapore/GP1908/2015, IVR-180) 15 micrograms HA, (A/Singapore/INFIMH-16-0019/2016, NIB-104) 15 micrograms HA, (B/Maryland/15/2016, NYMC BX-69A) 15 micrograms HA" ; obo:VO_0003147 "potassium chloride, potassium dihydrogen phosphate, disodium phosphate dihydrate, sodium chloride, calcium chloride dihydrate, magnesium chloride hexahydrate and water for injections" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Imuvac" ; rdfs:subClassOf obo:VO_0001485, obo:VO_0003143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003145 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003145 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Mylan Products Limited" . obo:VO_0003146 obo:IAO_0000115 "An annotation property that represents the active ingredient of a vaccine." ; obo:IAO_0000117 "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "has vaccine active ingredient" ; rdfs:subPropertyOf obo:VO_0003147 . obo:VO_0003147 obo:IAO_0000115 "An annotation property that represents the vaccine ingredient of a vaccine. Such an ingredient may not be active." ; obo:IAO_0000117 "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "has vaccine ingredient" . obo:VO_0003148 obo:IAO_0000115 "LIPO-5 is a therapeutic HIV vaccine made up of lipopeptides, Study Names: VRI02/ANRS 149 LIGHT; NCT01492985" ; obo:IAO_0000117 "Oliver He, Randi Vita" ; obo:IAO_0000118 "ANRS HIV-LIPO-5, HIV-LIPO-5" ; obo:IAO_0000119 "https://aidsinfo.nih.gov/drugs/572/lipo-5/0/patient" ; obo:VO_0003146 "5 synthetic HIV-1 peptide fragments, which contain multiple CD8 and CD4 cell epitopes: Gag (amino acids 17 to 35), Gag (amino acids 253 to 284), Pol (amino acids 325 to 355), Nef (amino acids 66 to 97), and Nef (amino acids 116 to 145). The peptides are covalently attached to a palmitoyl-lysylamide moiety that facilitates entry into antigen-presenting DCs and enhances vaccine immunogenicity" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "LIPO-5 is in Phase II development as a therapeutic HIV vaccine. (LIPO-5 is also being studied as a preventive HIV vaccine.)" ; rdfs:label "LIPO-5" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0003142 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003149 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003149 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "French National Agency for Research on AIDS and Viral Hepatitis (ANRS)" . obo:VO_0003150 obo:IAO_0000115 "A Hepatitis B virus vaccine that uses recombinant Hepatitis B surface antigen as the antigen" ; obo:IAO_0000117 "Oliver He, Kallan Roan" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/797752", "https://en.wikipedia.org/wiki/Hepatitis_B_vaccine" ; obo:VO_0003198 "797752" ; obo:VO_0003560 "Hepatitis B Surface Antigen Vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0062527", "RXAUI: 2850925", "TUI: T116, T129, T121" ; rdfs:label "Hepatitis B surface antigen vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000028 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000082 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003152 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000525 ; owl:someValuesFrom obo:VO_0011093 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0000525 ; owl:someValuesFrom obo:VO_0011093 ] . obo:VO_0003151 obo:IAO_0000115 "An annotation property that describes the dose information of a vaccine" ; obo:IAO_0000117 "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "vaccine dose annotation" . obo:VO_0003152 obo:IAO_0000115 "A Hepatitis B surface antigen viral vaccine that utilizes a cytidine-phosphate-guanosine oligodeoxynucleotide (CpGODN) 1018, as an adjuvant." ; obo:IAO_0000117 "Oliver He, Randi Vita, Kallan Roan" ; obo:IAO_0000118 "HBsAg-1018" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1994348", "https://www.ncbi.nlm.nih.gov/pubmed/22342916" ; obo:VO_0003198 "1994348" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HEPLISAV-B" ; rdfs:subClassOf obo:VO_0000644, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003150 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003153 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003153 obo:IAO_0000115 "A company trhat is located at Berkeley, CA, USA. Its website is: http://www.dynavax.com." ; obo:IAO_0000117 "Oliver He, Randi Rita, Kallan Roan" ; obo:IAO_0000119 "http://www.dynavax.com/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Dynavax Technologies Corporation" . obo:VO_0003154 obo:IAO_0000115 "A CpG DNA vaccine adjuvant that is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity." ; obo:IAO_0000116 "ISS 1018 is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity. ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin-12 (IL-12), and tumor necrosis factor - alpha (TNF-alpha) by plasmacytoid dendritic cells (pDC). ISS 1018 CpG ODN promotes antigen presentation and co-stimulatory molecule expression. ISS 1018 is currently being investigated in combination with HBsAg vaccine as a prophylactic treatment for to prevent Hepatitis B in adults. It is also being investigated in combination with rituximab for treatment of b-cell or non-hodgkin's lymphoma." ; obo:IAO_0000117 "Kallan Roan", "Oliver He" ; obo:IAO_0000118 "ISS 1018 CpG ODN", "ISS 1018 CpG oligodeoxynucleotide", "ISS-1018" ; obo:IAO_0000119 "https://www.cancer.gov/publications/dictionaries/cancer-drug/def/iss-1018-cpg-oligodeoxynucleotide", "https://www.drugbank.ca/drugs/DB05463" ; a owl:Class ; rdfs:label "ISS 1018 CpG ODN vaccine adjuvant" ; rdfs:seeAlso "DrugBank Accession number: DB05463" ; rdfs:subClassOf obo:VO_0001237 . obo:VO_0003155 obo:IAO_0000117 "Oliver He, Kallan Roan, Randi Rita" ; obo:IAO_0000119 "A recombinant vesicular stomatitis virus Indiana serotype (rVSV) vector vaccine taht expresses Zaire GP", "https://www.ncbi.nlm.nih.gov/pubmed/15937495" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rVSV-ZEBOV" ; rdfs:subClassOf obo:VO_0004660, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:VO_0010910 ] . obo:VO_0003156 obo:IAO_0000115 "A human paillomavirus vaccine that has the vaccine antigen ingredient of monovalent non-infectious, L1 recombinant HPV-like particles (VLP)." ; obo:IAO_0000117 "Oliver He, Kallan Roan, Randi Rita" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/12854090" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HPV-16 L1 VLP" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:VO_0011108 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003157 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003157 obo:IAO_0000115 "Novavax, Inc. is a clinical-stage biotechnology company committed to delivering novel products to prevent a broad range of infectious diseases." ; obo:IAO_0000119 "http://novavax.com/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Novavax, Inc." . obo:VO_0003158 obo:IAO_0000112 "The vaccine Prevnar (trade name) has a FDA-defined proper name: Pneumococcal 7-valent Conjugate Vaccine (Diphtheria CRM197 Protein). Reference: https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm" ; obo:IAO_0000115 "An annotation property that represents the proper name of a vaccine, which is defined in an official way such as one defined by FDA." ; obo:IAO_0000117 "Kallan Roan", "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "vaccine proper name" . obo:VO_0003159 obo:IAO_0000112 "The vaccine Prevnar has the manufacturer: Wyeth Pharmaceuticals Inc. Reference: https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm" ; obo:IAO_0000115 "An annotation property that represents the manufacturer of a vaccine" ; obo:IAO_0000117 "Kallan Roan", "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "vaccine manufacturer" . obo:VO_0003160 obo:IAO_0000112 """The vaccine Prevnar has the indications: - Immunization of infants 2, 4, 6 and 12-15 months of age to prevent invasive pneumococcal disease. - Immunization of infants and toddlers against otitis media caused by vaccine serotypes. Reference: https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm180017.htm""" ; obo:IAO_0000115 "An annotation property that represents the indications of a vaccine defined by the USA FDA." ; obo:IAO_0000117 "Kallan Roan", "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "FDA vaccine indications" . obo:VO_0003161 obo:IAO_0000112 "Prevnar has the package insert PDF URL: https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM137038.pdf . Recorded on 11/26/2018." ; obo:IAO_0000115 "An annotation property that represents a URL of the package insert PDF document of a licensed vaccine" ; obo:IAO_0000117 "Kallan Roan", "Oliver He" ; a owl:AnnotationProperty ; rdfs:label "vaccine package insert PDF URL" . obo:VO_0003162 obo:IAO_0000115 "An annotation property that indicate the number that is generated by FDA based on a request from an applicant of a product licensing." ; obo:IAO_0000117 "Kallan Roan", "Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/downloads/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/ProceduresSOPPs/UCM461225.pdf" ; a owl:AnnotationProperty ; rdfs:label "vaccine STN" . obo:VO_0003163 obo:IAO_0000117 "Kallan Roan, Oliver He" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Teva Pharmaceuticals USA, Inc." . obo:VO_0003164 obo:IAO_0000117 "Kallan Roan, Oliver He" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Seqirus, Inc." . obo:VO_0003165 obo:IAO_0000115 "An inactivated Japanese encephalitis vaccine (JVax *) for use by certain travelers to and expatriates in Asia." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.cdc.gov/mmwr/preview/mmwrhtml/00018184.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "J-Vax" ; rdfs:subClassOf obo:VO_0000665, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003166 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003166 obo:IAO_0000115 "Located in Swiftwater, Pennsylvania, this company is now known as Sanofi Pasteur Limited." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Connaught Laboratories, Inc." . obo:VO_0003167 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "A viral vaccine that protects against infection with Poliovirus administered orally.", "http://polioeradication.org/polio-today/polio-prevention/the-vaccines/opv/", "https://www.who.int/biologicals/areas/vaccines/polio/opv/en/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Oral Poliovirus vaccine" ; rdfs:subClassOf obo:VO_0000664, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003168 obo:IAO_0000115 "A combination vaccine that protects against diphtheria, tetanus, pertussis, and Haemophilus influenzae type B." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTaP-Hib vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Contains pertussis in acellular form." ; rdfs:label "Diphtheria-Tetanus-Acellular Pertussis-Haemophilus b vaccine" ; rdfs:subClassOf obo:VO_0000756, obo:VO_0000942 . obo:VO_0003169 obo:IAO_0000115 "A combination vaccine with whole cell that protects against diphtheria, tetanus, pertussis, and Haemophilus influenzae type B." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTP-Hib vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Contains killed whole cells of bacterium that causes pertussis." ; rdfs:label "Diphtheria-Tetanus-Whole Cell Pertussis-Haemophilus b vaccine" ; rdfs:subClassOf obo:VO_0000942 . obo:VO_0003170 obo:IAO_0000115 "A vaccine used to develop immunity to rabies." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Discontinued" ; rdfs:label "Imovax ID" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003019 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003171 obo:IAO_0000115 "A live virus vaccine for immunization against measles and rubella." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.rxlist.com/m-r-vax-ii-drug.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MR-VAX II" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000945, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0000007 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0000073 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003172 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTP-HepB vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Pertussis-Hepatitis B vaccine" ; rdfs:subClassOf obo:VO_0000644, obo:VO_0000738, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0003173 obo:IAO_0000115 "Active immunzation against diphtheria, tetanus, pertussis and hepatitis B (HBV) in infants from 6 weeks onwards" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Tritanrix HB" ; obo:IAO_0000119 "https://www.ema.europa.eu/en/tritanrix-hb-h-w-3838" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tritanrix" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0003172, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003174 obo:IAO_0000115 "A vaccine used to prevent diphtheria, tetanus, pertussis, and Haemophilus type B infections." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.hendricks.org/HealthLibrary/default.aspx?sid=1&pTitle=%2CDrug&ContentTypeID=26&ContentID=1027&alpha=A&AdditionalTitle=ActHIB%C2%AE+With+DTP" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DTP-ActHIB" ; rdfs:subClassOf obo:VO_0000942, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0000004 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000700 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003175 obo:IAO_0000115 "An oral vaccine against adenovirus serotype 4." ; obo:IAO_0000119 "https://health.mil/Military-Health-Topics/Health-Readiness/Immunization-Healthcare/Vaccine-Preventable-Diseases/Adenovirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Kallan Roan, Oliver He", "The vaccine is in a form of white enteric-coated tablets. It is typically administered with Adenovirus type 7 vaccine." ; rdfs:label "Adenovirus Type 4" ; rdfs:subClassOf obo:VO_0000037, obo:VO_0000367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004869 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003164 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003176 obo:IAO_0000115 "An oral vaccine against adenovirus serotype 7." ; obo:IAO_0000119 "Kallan Roan, Oliver He", "The vaccine is in a form of peach-colored enteric-coated tablets. It is typically administered with Adenovirus type 4 vaccine.", "https://health.mil/Military-Health-Topics/Health-Readiness/Immunization-Healthcare/Vaccine-Preventable-Diseases/Adenovirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Adenovirus Type 7" ; rdfs:subClassOf obo:VO_0000037, obo:VO_0000367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004871 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003164 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003177 obo:IAO_0000115 "A vaccine that contains ActHIB and protects against, Diphtheria, Tetanus, Pertussis (whooping cough), Polio, and Haemophilus influenzae type b." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTAP/IPV/ACT-HIB" ; obo:IAO_0000119 "https://insights.ovid.com/pubmed?pmid=9849987" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-ACT-Hib vaccine" ; rdfs:subClassOf obo:VO_0000744, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000807 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002180 ; owl:someValuesFrom obo:VO_0000004 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003166 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003178 obo:IAO_0000115 "Active immunization against tetanus, diphtheria, pertussis, and poliomyelitis for individuals between 3 months and 6 years of age." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.impfkritik.de/upload/pdf/fachinfo/quatro-virelon-chiron-behring.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Quatro Virelon" ; rdfs:subClassOf obo:VO_0000742, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003179 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003179 a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Chiron Behring Vaccines Private Ltd" . obo:VO_0003180 obo:IAO_0000115 "A vaccine that protects adolescents and adults from tetanus, diphtheria, and pertussis." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.cdc.gov/vaccines/hcp/vis/vis-statements/tdap.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Tdap is different than the DTaP vaccine, which is given to infants and children in five doses, starting at 2 months of age." ; rdfs:label "TDAP" ; rdfs:subClassOf obo:VO_0000738, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003181 obo:IAO_0000115 "A measles virus vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Measles virus vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000654, obo:VO_0003444 . obo:VO_0003182 obo:IAO_0000115 "A Mumps-Rubella vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Mumps-Rubella Vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0003418, obo:VO_0003444 . obo:VO_0003183 obo:IAO_0000115 "A Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine manufactured outside of the U.S" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Hepatitis B vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000743, obo:VO_0003444 . obo:VO_0003184 obo:IAO_0000115 "A Diphtheria-Tetanus-Pertussis-Poliovirus vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000742, obo:VO_0003444 . obo:VO_0003185 obo:IAO_0000115 "A Haemophilis influenzae Type b capsular polysaccharide vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.drugs.com/mmx/haemophilus-influenzae-type-b-polysaccharide-vaccine.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "HIB Polysaccharide foreign to USA" ; rdfs:subClassOf obo:VO_0000627, obo:VO_0003444 . obo:VO_0003186 obo:IAO_0000115 "A Hepatitis B vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.ema.europa.eu/documents/product-information/hbvaxpro-epar-product-information_en.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Hepatitis B vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000644, obo:VO_0003444 . obo:VO_0003187 obo:IAO_0000115 "A Diphtheria-Tetanus-Poliovirus vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166496/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Diphtheria-Tetanus-Poliovirus vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000943, obo:VO_0003444 . obo:VO_0003188 obo:IAO_0000115 "A Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.ema.europa.eu/medicines/human/EPAR/hexyon" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b-Hepatitis B vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000946, obo:VO_0003444 . obo:VO_0003189 obo:IAO_0000115 "A seasonal Influenza virus vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://www.euro.who.int/en/health-topics/communicable-diseases/influenza/vaccination/types-of-seasonal-influenza-vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Seasonal Influenza virus vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000642, obo:VO_0003444 . obo:VO_0003190 obo:IAO_0000115 "A Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine manufactured outside of the U.S" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DTaP/IPV/Hib vaccine foreign to USA" ; obo:IAO_0000119 "https://ca.gsk.com/media/590970/infanrix-ipv-hib.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Diphtheria-Tetanus-Pertussis-Poliovirus-Haemophilus b vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000744, obo:VO_0003444 . obo:VO_0003191 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://vk.ovg.ox.ac.uk/ppv" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A pneumococcal vaccine manufactured outside of the U.S.", "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Pneumococcal vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000424, obo:VO_0003444 . obo:VO_0003192 obo:IAO_0000115 "An active immunizing combination agent that is used to prevent infection caused by certain groups of meningococcal bacteria and Haemophilus influenza type b (Hib) bacteria." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.mayoclinic.org/drugs-supplements/meningococcal-vaccine-and-haemophilus-b-vaccine-intramuscular-route/description/drg-20075601" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Meningococcal Conjugate and Haemophilis B Vaccine" ; rdfs:subClassOf obo:VO_0000662, obo:VO_0003441, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] . obo:VO_0003193 obo:IAO_0000115 "A Meningicoccal Conjugate and Haemophilis B Vaccine manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Meningococcal Conjugate and Haemophilis B Vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0003192, obo:VO_0003444 . obo:VO_0003194 obo:IAO_0000115 "A tick-borne encephalitis virus vaccine used to prevent subtype Far Eastern tick-borne encephalitis virus (formerly known as Russian Spring Summer encephalitis virus)." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.who.int/immunization/sage/1_TBE_PP_Draft_13_Mar_2011_SAGE_apr_2011.pdf?ua=1" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Spring Summer Encephalitis Vaccine" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0012190, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003195 obo:IAO_0000115 "A polysaccharide vaccine to prevent typhoid caused Salmonella typhi. Acetone is used to inactivate culture, and dried." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.cdc.gov/mmwr/pdf/rr/rr4314.pdf", "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366340" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Acetone-Dried Typhoid Vi Polysaccharide vaccine" ; rdfs:subClassOf obo:VO_0001214, obo:VO_0003443, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003022 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003196 obo:IAO_0000118 "acellular pertussis vaccine, inactivated" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798302" ; obo:VO_0003198 "798302" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "inactivated acellular pertussis vaccine" ; rdfs:subClassOf obo:VO_0000765 . obo:VO_0003197 obo:IAO_0000115 "A vaccine to protect individuals against infections caused by hepatitis A virus and typhoid fever bacteria." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Hepatitis A and Vi Polysaccharide typhoid vaccine foreign to USA" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/9772328" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "Hepatitis A virus-Typhoid vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0003229, obo:VO_0003444, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003198 a owl:AnnotationProperty ; rdfs:label "RxNORM ID" . obo:VO_0003199 obo:IAO_0000118 "B. pertussis pertactin vaccine", "Bordetella pertussis pertactin vaccine" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300380" ; obo:VO_0003198 "1300380" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis pertactin vaccine, inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003196, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000015 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000029 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000064 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003200 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300186" ; obo:VO_0003198 "1300186" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis toxoid vaccine, inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003196, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000015 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000029 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000064 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003201 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003196, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000015 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000029 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000064 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003202 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300182" ; obo:VO_0003198 "1300182" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis fimbriae 2/3 vaccine, inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003196, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000029 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003203 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300380" ; obo:VO_0003198 "1300380" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML" ; rdfs:subClassOf obo:VO_0003199 . obo:VO_0003204 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300185" ; obo:VO_0003198 "1300185" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML" ; rdfs:subClassOf obo:VO_0003199 . obo:VO_0003205 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657600" ; obo:VO_0003198 "1300365" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis pertactin vaccine, inactivated 0.005 UNT/ML" ; rdfs:subClassOf obo:VO_0003199 . obo:VO_0003206 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300366" ; obo:VO_0003198 "1300366" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML" ; rdfs:subClassOf obo:VO_0003200 . obo:VO_0003207 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300381" ; obo:VO_0003198 "1300381" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003200 . obo:VO_0003208 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300187" ; obo:VO_0003198 "1300187" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML" ; rdfs:subClassOf obo:VO_0003200 . obo:VO_0003209 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300307" ; obo:VO_0003198 "1300307" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.02 MG/ML" ; rdfs:subClassOf obo:VO_0003200 . obo:VO_0003210 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1988802" ; obo:VO_0003198 "1988802" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML" ; rdfs:subClassOf obo:VO_0003200 . obo:VO_0003211 obo:IAO_0000115 "A monovalent vaccine used to protect against H1N1 influenza virus." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm181950.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H1N1 Influenza Monovalent Vaccine" ; rdfs:subClassOf obo:VO_0000578, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0003212 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854930" ; obo:VO_0003198 "854930" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003213 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "DP+IPV vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria Toxoid-Pertussis-Poliovirus vaccine" ; rdfs:subClassOf obo:VO_0000735, obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:NCBITaxon_12080 obo:NCBITaxon_12083 obo:NCBITaxon_12086 ) ] ] . obo:VO_0003214 obo:IAO_0000118 "DT+IPV+HIB+HEPB vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Tetanus-Poliovirus-Haemophilus B-Hepatitis B vaccine" ; rdfs:subClassOf obo:VO_0000732, obo:VO_0000746, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_10407 obo:VO_0000741 [ a owl:Class ; owl:unionOf (obo:NCBITaxon_12080 obo:NCBITaxon_12083 obo:NCBITaxon_12086 ) ] ) ] ] . obo:VO_0003215 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Seasonal Influenza A27:H29 vaccine" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0003216 obo:IAO_0000115 """For the prevention of influenza caused by Influenza Virus, Types A and B. For the Southern Hemisphere 2017 season, the vaccine is indicated for use only in persons aged 5 years and over.""" ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.medsafe.govt.nz/profs/Datasheet/f/Fluvaxinj.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluvax" ; rdfs:subClassOf obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000689 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003217 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854934" ; obo:VO_0003198 "854934" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 11A vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003218 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854936" ; obo:VO_0003198 "854936" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 12F vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003219 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854938" ; obo:VO_0003198 "854938" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 14 vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003220 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854940" ; obo:VO_0003198 "854940" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 15B vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003221 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854942" ; obo:VO_0003198 "854942" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 17F vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003222 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854944" ; obo:VO_0003198 "854944" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 18C vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003223 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854944" ; obo:VO_0003198 "854944" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 19A vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003224 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854948" ; obo:VO_0003198 "854948" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 19F vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003225 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854950" ; obo:VO_0003198 "854950" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 2 vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003226 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854952" ; obo:VO_0003198 "854952" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 20 vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003227 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854954" ; obo:VO_0003198 "854954" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 22F vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003228 obo:IAO_0000118 "1 ML Recombivax 0.04 MG/ML Injection", "RECOMBIVAX HB dialysis formulation vaccine 1 ML Injection", "Recombivax HB 40 MCG per 1 ML Injection", "Recombivax HB, Hepatitis B vaccine (recombinant) Dialysis Formulation 40 MCG per 1 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830263" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection [Recombivax]" ; rdfs:subClassOf obo:VO_0010737 . obo:VO_0003229 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A virus-Typhoid vaccine" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000646, obo:VO_0000671 . obo:VO_0003230 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830260" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML" ; rdfs:subClassOf obo:VO_0003150 . obo:VO_0003231 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1994352" ; obo:VO_0003198 "1994352" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4534702", "RXAUI: 9712934, 9712933, 9712931, 9712937", "TUI: T200" ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection [Heplisav-B]" ; rdfs:subClassOf obo:VO_0003270, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003968 ] . obo:VO_0003232 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854962" ; obo:VO_0003198 "854962" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 4 vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003233 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection" ; rdfs:subClassOf obo:VO_0003421 . obo:VO_0003234 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Injection" ; rdfs:subClassOf obo:VO_0003421 . obo:VO_0003235 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657331" ; obo:VO_0003198 "1657331" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0000200 . obo:VO_0003236 obo:IAO_0000115 "A vaccine which helps prevent hepatitis A and typhoid fever. This vaccine should only be given to adults and teenagers aged 15 years and above." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.hpra.ie/img/uploaded/vaccines/PIL_PA1077099001.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatyrix" ; rdfs:subClassOf obo:VO_0000712, obo:VO_0001214, obo:VO_0003229, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003237 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830212" ; obo:VO_0003198 "830212" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML [Recombivax]" ; rdfs:subClassOf obo:VO_0010737 . obo:VO_0003238 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658155" ; obo:VO_0003198 "1658155" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [Recombivax]" ; rdfs:subClassOf obo:VO_0003237 . obo:VO_0003239 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830245" ; obo:VO_0003198 "830245" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]" ; rdfs:subClassOf obo:VO_0003237 . obo:VO_0003240 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BCG Vaccine (by Organon Teknika)" ; rdfs:subClassOf obo:VO_0000771, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003052 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000697 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003241 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658150" ; obo:VO_0003198 "1658150" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [Recombivax]" ; rdfs:subClassOf obo:VO_0003237 . obo:VO_0003242 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657683" ; obo:VO_0003198 "1657683" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Injection [Recombivax]" ; rdfs:subClassOf obo:VO_0010737 . obo:VO_0003243 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830244" ; obo:VO_0003198 "830244" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Recombivax]" ; rdfs:subClassOf obo:VO_0010737 . obo:VO_0003244 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830253" ; obo:VO_0003198 "830253" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe [Recombivax]" ; rdfs:subClassOf obo:VO_0003243 . obo:VO_0003245 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombivax Injectable Product" ; rdfs:subClassOf obo:VO_0010737 . obo:VO_0003246 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854970" ; obo:VO_0003198 "854970" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 8 vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003247 obo:IAO_0000115 "The site that is the part of the host body and the entrance point where a vaccine is administered. " ; obo:IAO_0000117 "YL" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:comment "it is not the natural anatomical part where the body has access toward outside, such as mouth or nose. But rather the holes on the skin made by needdles used for vaccination." ; rdfs:label "vaccination site" ; rdfs:subClassOf obo:BFO_0000029, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000574 ] . obo:VO_0003248 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854958" ; obo:VO_0003198 "854958" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 3 vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003249 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854960" ; obo:VO_0003198 "854960" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 33F vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003250 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854966" ; obo:VO_0003198 "854966" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 6B vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003251 obo:IAO_0000115 "A trivalent inactive influenza virus vaccine." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Flu-imune" ; obo:IAO_0000119 "https://cvi.asm.org/content/cdli/1/1/16.full.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Vaccine sold for 1993-1994 influenza season." ; rdfs:label "Flu-Imune" ; rdfs:subClassOf obo:VO_0002495, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003089 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003252 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854956" ; obo:VO_0003198 "854956" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 23F vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003253 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854968" ; obo:VO_0003198 "854968" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 7F vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003254 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854972" ; obo:VO_0003198 "854972" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 9N vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003255 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854972" ; obo:VO_0003198 "854972" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 5 vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003256 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/797753" ; obo:VO_0003198 "797753" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML" ; rdfs:subClassOf obo:VO_0003150 . obo:VO_0003257 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830236" ; obo:VO_0003198 "830236" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML" ; rdfs:subClassOf obo:VO_0003150 . obo:VO_0003258 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798427" ; obo:VO_0003198 "798427" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Engerix-B]" ; rdfs:subClassOf obo:VO_0015019 . obo:VO_0003259 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658156" ; obo:VO_0003198 "1658156" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection" ; rdfs:subClassOf obo:VO_0003421 . obo:VO_0003260 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658708" ; obo:VO_0003198 "1658708" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0000200 . obo:VO_0003261 obo:IAO_0000115 "A quadrivalent influenza vaccine against two influenza A strains and two influenza B strains." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/24022123" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "QIV Dresden" ; rdfs:subClassOf obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003262 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658142" ; obo:VO_0003198 "1658142" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection" ; rdfs:subClassOf obo:VO_0003421 . obo:VO_0003263 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798422" ; obo:VO_0003198 "798422" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Engerix-B]" ; rdfs:subClassOf obo:VO_0010711 . obo:VO_0003264 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798428" ; obo:VO_0003198 "798428" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B]" ; rdfs:subClassOf obo:VO_0003258 . obo:VO_0003265 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658157" ; obo:VO_0003198 "1658157" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B]" ; rdfs:subClassOf obo:VO_0015020 . obo:VO_0003266 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658144" ; obo:VO_0003198 "1658144" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Engerix-B]" ; rdfs:subClassOf obo:VO_0015020 . obo:VO_0003267 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798430" ; obo:VO_0003198 "798430" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Engerix-B]" ; rdfs:subClassOf obo:VO_0003258 . obo:VO_0003268 obo:IAO_0000115 "A combination vaccine against diphtheria, tetanus, pertussis, poliomyelitis, and Haemophilus influenzae type b (Hib)." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.mesvaccins.net/web/vaccines/15-infanrixquinta" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infanrix Quinta" ; rdfs:subClassOf obo:VO_0000744, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003269 obo:IAO_0000117 "Oliver He, Khadeejah Khan" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854937" ; obo:VO_0003198 "854937" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 12F vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003218 . obo:VO_0003270 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1994350" ; obo:VO_0003198 "1994350" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Injection [Heplisav-B]" ; rdfs:subClassOf obo:VO_0003965 . obo:VO_0003271 obo:IAO_0000115 "A combination vaccine against diphtheria, tetanus, pertussis, hepatitis B, and poliovirus." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://www.gsk.com.au/resources.ashx/vaccineproductschilddataproinfo/28/FileName/700FA5039310414550A80719A7B644CD/PI_Infanrix_Penta.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infanrix Penta" ; rdfs:subClassOf obo:VO_0000743, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003272 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292432" ; obo:VO_0003198 "1292432" ; oboInOwl:hasAlternativeId "VO:0003280" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Injection" ; rdfs:subClassOf obo:VO_0003279 . obo:VO_0003273 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292422" ; obo:VO_0003198 "1292422" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain" ; rdfs:subClassOf obo:VO_0000419 . obo:VO_0003274 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658006" ; obo:VO_0003198 "1658006" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection" ; rdfs:subClassOf obo:VO_0003273 . obo:VO_0003275 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292423" ; obo:VO_0003198 "1292423" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML" ; rdfs:subClassOf obo:VO_0003273 . obo:VO_0003276 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292457" ; obo:VO_0003198 "1292457" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injection" ; rdfs:subClassOf obo:VO_0003275 . obo:VO_0003277 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292424" ; obo:VO_0003198 "1292424" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injectable Product" ; rdfs:subClassOf obo:VO_0000419 . obo:VO_0003278 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292436" ; obo:VO_0003198 "1292436" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 20000 UNT/ML" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003273, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000091 ] . obo:VO_0003279 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292430" ; obo:VO_0003198 "1292430" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML" ; rdfs:subClassOf obo:VO_0003273 . obo:VO_0003280 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292432" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0003272 ; a owl:Class ; rdfs:label "obsolete 0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Injection" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0003281 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658013" ; obo:VO_0003198 "1658013" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection [Zostavax]" ; rdfs:subClassOf obo:VO_0000124 . obo:VO_0003282 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292433" ; obo:VO_0003198 "1292433" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML [Zostavax]" ; rdfs:subClassOf obo:VO_0003281 . obo:VO_0003283 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292435" ; obo:VO_0003198 "1292435" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.65 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 29800 UNT/ML Injection [Zostavax]" ; rdfs:subClassOf obo:VO_0003282 . obo:VO_0003284 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide vaccine" ; rdfs:subClassOf obo:VO_0000675 . obo:VO_0003285 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000675 . obo:VO_0003286 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901622" ; obo:VO_0003198 "901622" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003335 . obo:VO_0003287 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901627" ; obo:VO_0003198 "901627" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003340 . obo:VO_0003288 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901630" ; obo:VO_0003198 "901630" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003342 . obo:VO_0003289 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901621" ; obo:VO_0003198 "901621" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003334 . obo:VO_0003290 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901635" ; obo:VO_0003198 "901635" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0088 MG/ML" ; rdfs:subClassOf obo:VO_0003345 . obo:VO_0003291 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901638" ; obo:VO_0003198 "901638" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003346 . obo:VO_0003292 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901626" ; obo:VO_0003198 "901626" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003339 . obo:VO_0003293 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901629" ; obo:VO_0003198 "901629" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003341 . obo:VO_0003294 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901632" ; obo:VO_0003198 "901632" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003343 . obo:VO_0003295 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901634" ; obo:VO_0003198 "901634" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003344 . obo:VO_0003296 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901625" ; obo:VO_0003198 "901625" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003338 . obo:VO_0003297 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901623" ; obo:VO_0003198 "901623" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003337 . obo:VO_0003298 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901637" ; obo:VO_0003198 "901637" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML" ; rdfs:subClassOf obo:VO_0003333 . obo:VO_0003299 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus Vaccine" ; rdfs:subClassOf obo:VO_0000667 . obo:VO_0003300 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798268" ; obo:VO_0003198 "798268" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 6 Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000049 ] . obo:VO_0003301 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798262" ; obo:VO_0003198 "798262" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000049 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003307 ] . obo:VO_0003302 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798266" ; obo:VO_0003198 "798266" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 18 Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000049 ] . obo:VO_0003303 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798264" ; obo:VO_0003198 "798264" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000049 ] . obo:VO_0003304 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1596930" ; obo:VO_0003198 "1596930" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 31 Vaccine" ; rdfs:subClassOf obo:VO_0003299 . obo:VO_0003305 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1596931" ; obo:VO_0003198 "1596931" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 33 Vaccine" ; rdfs:subClassOf obo:VO_0003299 . obo:VO_0003306 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1596932" ; obo:VO_0003198 "1596932" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 45 Vaccine" ; rdfs:subClassOf obo:VO_0003299 . obo:VO_0003307 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1596933" ; obo:VO_0003198 "1596933" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 52 Vaccine" ; rdfs:subClassOf obo:VO_0003299 . obo:VO_0003308 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1596934" ; obo:VO_0003198 "1596934" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L1 protein, Human papillomavirus type 58 Vaccine" ; rdfs:subClassOf obo:VO_0003299 . obo:VO_0003309 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854957" ; obo:VO_0003198 "854957" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 23F vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003252 . obo:VO_0003310 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854939" ; obo:VO_0003198 "854939" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 14 vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003219 . obo:VO_0003311 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854969" ; obo:VO_0003198 "854969" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 7F vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003253 . obo:VO_0003312 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854965" ; obo:VO_0003198 "854965" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 5 vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003255 . obo:VO_0003313 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854935" ; obo:VO_0003198 "854935" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 11A vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003217 . obo:VO_0003314 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854933" ; obo:VO_0003198 "854933" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 10A vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003959 . obo:VO_0003315 obo:IAO_0000115 "A combination vaccine against diphtheria, tetanus, acellular pertussis, and inactivated poliomyelitis for individuals ages from 16 months to 13 years of age." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.mesvaccins.net/web/vaccines/51-infanrixtetra" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infanrix Tetra" ; rdfs:subClassOf obo:VO_0000742, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003316 obo:IAO_0000115 "A vaccine that can be given to children after the age of 2 months up to 2 years to prevent infectious diseases caused by Haemophilus influenzae type b (Hib) and Neisseria meningitidis group C (MenC) bacteria." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.medicines.org.uk/emc/files/pil.167.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Menitorix" ; rdfs:subClassOf obo:VO_0003192, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003317 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:VO_0003099 "SHINGRIX" ; obo:VO_0003158 "Zoster Vaccine Recombinant, Adjuvanted" ; obo:VO_0003160 "Indicated for prevention of herpes zoster (shingles) in adults aged 50 years and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM581605.pdf" ; obo:VO_0003162 "125614" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shingrix" ; rdfs:subClassOf obo:VO_0000669, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003802 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003318 obo:IAO_0000115 "A vaccine against tetanus, diphtheria, pertussis, and inactivated poliovirus manufactured outside of the U.S." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.nhsinform.scot/healthy-living/immunisation/vaccines/the-4-in-1-vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; rdfs:label "TDAP/IPV vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0003180, obo:VO_0003444, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:unionOf (obo:NCBITaxon_12080 obo:NCBITaxon_12083 obo:NCBITaxon_12086 ) ] ] . obo:VO_0003319 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854941" ; obo:VO_0003198 "854941" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 15B vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003220 . obo:VO_0003320 obo:IAO_0000117 "Oliver He, Khadeejah Khan" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854943" ; obo:VO_0003198 "854943" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 17F vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003221 . obo:VO_0003321 obo:IAO_0000117 "Oliver He, Khadeejah Khan" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854945" ; obo:VO_0003198 "854945" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 18C vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003222 . obo:VO_0003322 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854947" ; obo:VO_0003198 "854947" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 19A vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003223 . obo:VO_0003323 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854931" ; obo:VO_0003198 "854931" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003212 . obo:VO_0003324 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854949" ; obo:VO_0003198 "854949" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 19F vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003224 . obo:VO_0003325 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854951" ; obo:VO_0003198 "854951" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 2 vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003225 . obo:VO_0003326 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854953" ; obo:VO_0003198 "854953" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 20 vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003226 . obo:VO_0003327 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854955" ; obo:VO_0003198 "854955" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 22F vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003227 . obo:VO_0003328 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854959" ; obo:VO_0003198 "854959" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 3 vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003248 . obo:VO_0003329 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854961" ; obo:VO_0003198 "854961" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 33F vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003249 . obo:VO_0003330 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854963" ; obo:VO_0003198 "854963" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 4 vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003232 . obo:VO_0003331 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854971" ; obo:VO_0003198 "854971" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 8 vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003246 . obo:VO_0003332 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854973" ; obo:VO_0003198 "854973" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 9N vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003254 . obo:VO_0003333 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901636" ; obo:VO_0003198 "901636" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003334 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901620" ; obo:VO_0003198 "901620" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003335 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798220" ; obo:VO_0003198 "798220" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003336 obo:IAO_0000115 "a vaccine-induced down-regulation gene expression that occurs in live attenuated vaccine and compared with the host system infected with live wild type virulent strain which is the parent strain of this live attenuated vaccine. " ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "live attenuated vaccine-induced down-regulated gene expression compared to infection with wild type pathogen" ; rdfs:subClassOf obo:VO_0000239 . obo:VO_0003337 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798222" ; obo:VO_0003198 "798222" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003338 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901624" ; obo:VO_0003198 "901624" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003339 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798224" ; obo:VO_0003198 "798224" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003340 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "vhttp://purl.bioontology.org/ontology/RXNORM/798226" ; obo:VO_0003198 "798226" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003341 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901628" ; obo:VO_0003198 "901628" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003342 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798228" ; obo:VO_0003198 "798228" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003343 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901631" ; obo:VO_0003198 "901631" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003344 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901633" ; obo:VO_0003198 "901633" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003345 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798230" ; obo:VO_0003198 "798230" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003346 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798232" ; obo:VO_0003198 "798232" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003285, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001244 ] . obo:VO_0003347 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593128" ; obo:VO_0003198 "1593128" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal group B vaccine" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003066 ] . obo:VO_0003348 obo:IAO_0000115 "A vaccine-induced up-regulation gene expression that occurs in live attenuated vaccine and compared with the host system infected with live wild type virulent strain which is the parent strain of this live attenuated vaccine. " ; obo:IAO_0000117 "YH, RR" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "live attenuated vaccine-induced up-regulated gene expression compared to infection with wild type pathogen" ; rdfs:subClassOf obo:VO_0000569 . obo:VO_0003349 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601397" ; obo:VO_0003198 "1601397" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal group B vaccine 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0003347 . obo:VO_0003350 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593133" ; obo:VO_0003198 "1593133" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal group B vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003351 . obo:VO_0003351 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593132" ; obo:VO_0003198 "1593132" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal group B vaccine Injectable Product" ; rdfs:subClassOf obo:VO_0000053 . obo:VO_0003352 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300181" ; obo:VO_0003198 "1300181" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML" ; rdfs:subClassOf obo:VO_0003201 . obo:VO_0003353 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm094070.htm" ; obo:VO_0003099 "Vivotif" ; obo:VO_0003158 "Typhoid Vaccine Live Oral Ty21a" ; obo:VO_0003160 "For immunization of adults and children greater than 6 years of age against disease caused by Salmonella typhi." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142807.pdf" ; obo:VO_0003162 "103123" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vivotif" ; rdfs:seeAlso "CVX: 25" ; rdfs:subClassOf obo:VO_0000671, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000687 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003354 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/762601" ; obo:VO_0003198 "762601" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a Delayed Release Oral Capsule [Vivotif]" ; rdfs:subClassOf obo:VO_0003357 . obo:VO_0003355 obo:IAO_0000115 """A shortcut relation that equals to: processed material and (is_specified_output_of some vaccine preparation) and (has function some (vaccine function and (is realized by only (vaccine immunization and (realizes some ('immunization target role' and (role_of some 'MICROBE')))))))) The domain of this relation is a vaccine. The range of this relation is a microbe (a bacterium, a virus, a fungus, and a parasite)""" ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000118 "immunization against microbe", "vaccine immunization against microbe" ; a owl:ObjectProperty ; rdfs:domain obo:VO_0000001 ; rdfs:label "immunizes against microbe" ; rdfs:range obo:OBI_0100026 . obo:VO_0003356 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/762602" ; obo:VO_0003198 "762602" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a 2000000000 UNT Delayed Release Oral Capsule [Vivotif]" ; rdfs:subClassOf obo:VO_0003354 . obo:VO_0003357 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1187406" ; obo:VO_0003198 "1187406" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vivotif Oral Product" ; rdfs:subClassOf obo:VO_0003353 . obo:VO_0003358 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1187407" ; obo:VO_0003198 "1187407" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vivotif Pill" ; rdfs:subClassOf obo:VO_0003353 . obo:VO_0003359 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601405" ; obo:VO_0003198 "1601405" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal group B vaccine Prefilled Syringe [Bexsero]" ; rdfs:subClassOf obo:VO_0004851 . obo:VO_0003360 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601231" ; obo:VO_0003198 "1601231" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen" ; rdfs:subClassOf obo:VO_0003960, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003066 ] . obo:VO_0003361 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601398" ; obo:VO_0003198 "1601398" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0003360 . obo:VO_0003362 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601233" ; obo:VO_0003198 "1601233" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen" ; rdfs:subClassOf obo:VO_0003960, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003066 ] . obo:VO_0003363 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601399" ; obo:VO_0003198 "1601399" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0003362 . obo:VO_0003364 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601236" ; obo:VO_0003198 "1601236" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003066 ] . obo:VO_0003365 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601400" ; obo:VO_0003198 "1601400" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003364 . obo:VO_0003366 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593127" ; obo:VO_0003198 "1593127" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen" ; rdfs:subClassOf obo:VO_0003960, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003081 ] . obo:VO_0003367 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593129" ; obo:VO_0003198 "1593129" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003366 . obo:VO_0003368 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593130" ; obo:VO_0003198 "1593130" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003081 ] . obo:VO_0003369 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593131" ; obo:VO_0003198 "1593131" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003368 . obo:VO_0003370 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601232" ; obo:VO_0003198 "1601232" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup B recombinant NADA fusion protein antigen" ; rdfs:subClassOf obo:VO_0003960 . obo:VO_0003371 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/804187" ; obo:VO_0003198 "804187" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain" ; rdfs:subClassOf obo:VO_0000123, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000121 ] . obo:VO_0003372 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1876704" ; obo:VO_0003198 "1876704" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML" ; rdfs:subClassOf obo:VO_0003371 . obo:VO_0003373 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1876705" ; obo:VO_0003198 "1876705" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injection" ; rdfs:subClassOf obo:VO_0003372 . obo:VO_0003374 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300183" ; obo:VO_0003198 "1300183" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML" ; rdfs:subClassOf obo:VO_0003202 . obo:VO_0003375 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1162391" ; obo:VO_0003198 "1162391" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain Injectable Product" ; rdfs:subClassOf obo:VO_0003371 . obo:VO_0003376 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1876709" ; obo:VO_0003198 "1876709" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Stamaril Injectable Product" ; rdfs:subClassOf obo:VO_0003139 . obo:VO_0003377 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1876708" ; obo:VO_0003198 "1876708" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain Injection [Stamaril]" ; rdfs:subClassOf obo:VO_0003139 . obo:VO_0003378 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1876710" ; obo:VO_0003198 "1876710" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 2000 UNT/ML Injection [Stamaril]" ; rdfs:subClassOf obo:VO_0003377 . obo:VO_0003379 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658238" ; obo:VO_0003198 "1658238" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain Injection" ; rdfs:subClassOf obo:VO_0003371 . obo:VO_0003380 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658239" ; obo:VO_0003198 "1658239" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML Injection" ; rdfs:subClassOf obo:VO_0003381 . obo:VO_0003381 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/804188" ; obo:VO_0003198 "804188" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML" ; rdfs:subClassOf obo:VO_0003371 . obo:VO_0003382 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292826" ; obo:VO_0003198 "1292826" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML Injectable Suspension" ; rdfs:subClassOf obo:VO_0003381 . obo:VO_0003383 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798305" ; obo:VO_0003198 "798305" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated 5 UNT/ML" ; rdfs:subClassOf obo:VO_0003455 . obo:VO_0003384 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798306" ; obo:VO_0003198 "798306" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003396, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000015 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000029 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000064 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000082 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000084 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003385 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798307" ; obo:VO_0003198 "798307" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML" ; rdfs:subClassOf obo:VO_0003384 . obo:VO_0003386 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300379" ; obo:VO_0003198 "1300379" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003201 . obo:VO_0003387 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300364" ; obo:VO_0003198 "1300364" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML" ; rdfs:subClassOf obo:VO_0003201 . obo:VO_0003388 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1988801" ; obo:VO_0003198 "1988801" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML" ; rdfs:subClassOf obo:VO_0003201 . obo:VO_0003389 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Acellular Pertussis Vaccine" ; rdfs:subClassOf obo:VO_0000165 . obo:VO_0003390 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798302" ; obo:VO_0003198 "798302" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "acellular pertussis vaccine, inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003389, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000082 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000084 ] . obo:VO_0003391 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/829893" ; obo:VO_0003198 "829893" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML" ; rdfs:subClassOf obo:VO_0003390 . obo:VO_0003392 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/801826" ; obo:VO_0003198 "801826" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML" ; rdfs:subClassOf obo:VO_0003390 . obo:VO_0003393 obo:IAO_0000115 "A trivalent influenza vaccine contianing two A influenza strains and one B influenza strain." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.clinicalleader.com/doc/results-phase-presented-gsks-quadrivalent-influenza-vaccines-0001" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "TIV Dresden" ; rdfs:subClassOf obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003394 obo:IAO_0000115 "An inactivated quadrivalent influenza vaccine against 2 influenza A strains and 2 influenza B strains for infants 6 months up to 23 months, and if needed it can be administered to children 2 to 17 years old with compromised immune systems and those considered vulnerable and high risk." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://globalnews.ca/news/2254967/a-first-for-flu-season-a-new-more-robust-four-strain-vaccine/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "QIV Quebec" ; rdfs:subClassOf obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003395 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/805373" ; obo:VO_0003198 "805373" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated 30 UNT/ML" ; rdfs:subClassOf obo:VO_0003455 . obo:VO_0003396 obo:IAO_0000115 "A clostridium tetani vaccine that consists of formaldehyde inactivated tetanospasmin (aka tetanus toxoid)." ; obo:IAO_0000117 "Oliver He, Hector Guzman-Orozco" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Clostridium_tetani" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine" ; rdfs:subClassOf obo:VO_0000640 . obo:VO_0003397 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/374054" ; obo:VO_0003198 "374054" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated Injectable Solution" ; rdfs:subClassOf obo:VO_0003399 . obo:VO_0003398 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/374444" ; obo:VO_0003198 "374444" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated Injectable Suspension" ; rdfs:subClassOf obo:VO_0003399 . obo:VO_0003399 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1164846" ; obo:VO_0003198 "1164846" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated Injectable Product" ; rdfs:subClassOf obo:VO_0003396 . obo:VO_0003400 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/792155" ; obo:VO_0003198 "792155" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003399 . obo:VO_0003401 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/801712" ; obo:VO_0003198 "801712" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated 20 UNT/ML" ; rdfs:subClassOf obo:VO_0003384 . obo:VO_0003402 obo:IAO_0000117 "Khadeejh khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/792156" ; obo:VO_0003198 "792156" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003400 . obo:VO_0003403 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/204527" ; obo:VO_0003198 "204527" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated 10 UNT/ML Injectable Suspension" ; rdfs:subClassOf obo:VO_0003398 . obo:VO_0003404 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/205262" ; obo:VO_0003198 "205262" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated 20 UNT/ML Injectable Suspension" ; rdfs:subClassOf obo:VO_0003398 . obo:VO_0003405 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/318242" ; obo:VO_0003198 "318242" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated 8 UNT/ML Injectable Solution" ; rdfs:subClassOf obo:VO_0003397 . obo:VO_0003406 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/316782" ; obo:VO_0003198 "316782" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated 8 UNT/ML" ; rdfs:subClassOf obo:VO_0003384 . obo:VO_0003407 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/331444" ; obo:VO_0003198 "331444" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid vaccine, inactivated 4 UNT/ML" ; rdfs:subClassOf obo:VO_0003384 . obo:VO_0003408 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798444" ; obo:VO_0003198 "798444" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000028 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000083 ] . obo:VO_0003409 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657731" ; obo:VO_0003198 "1657731" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injection" ; rdfs:subClassOf obo:VO_0003410 . obo:VO_0003410 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1159739" ; obo:VO_0003198 "1159739" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injectable Product" ; rdfs:subClassOf obo:VO_0003408 . obo:VO_0003411 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798447" ; obo:VO_0003198 "798447" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML Injection" ; rdfs:subClassOf obo:VO_0003409 . obo:VO_0003412 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657733" ; obo:VO_0003198 "1657733" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injection [PedvaxHIB]" ; rdfs:subClassOf obo:VO_0003410 . obo:VO_0003413 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798445" ; obo:VO_0003198 "798445" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML" ; rdfs:subClassOf obo:VO_0003408 . obo:VO_0003414 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798451" ; obo:VO_0003198 "798451" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML Injection [PedvaxHIB]" ; rdfs:subClassOf obo:VO_0003412 . obo:VO_0003415 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1160330" ; obo:VO_0003198 "1160330" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Product" ; rdfs:subClassOf obo:VO_0003150 . obo:VO_0003416 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798420" ; obo:VO_0003198 "798420" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003415 . obo:VO_0003417 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830237" ; obo:VO_0003198 "830237" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine 0.005 MG/ML Injectable Suspension" ; rdfs:subClassOf obo:VO_0003416 . obo:VO_0003418 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mumps-Rubella Vaccine" ; rdfs:subClassOf obo:VO_0000656, obo:VO_0010637, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11041 ] . obo:VO_0003419 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798425" ; obo:VO_0003198 "798425" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003415 . obo:VO_0003420 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798426" ; obo:VO_0003198 "798426" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003419 . obo:VO_0003421 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657681" ; obo:VO_0003198 "1657681" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Injection" ; rdfs:subClassOf obo:VO_0003415 . obo:VO_0003422 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830243" ; obo:VO_0003198 "830243" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003419 . obo:VO_0003423 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798438" ; obo:VO_0003198 "798438" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine 0.01 MG/ML" ; rdfs:subClassOf obo:VO_0003150 . obo:VO_0003424 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830252" ; obo:VO_0003198 "830252" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003419 . obo:VO_0003425 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798429" ; obo:VO_0003198 "798429" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003419 . obo:VO_0003426 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658149" ; obo:VO_0003198 "1658149" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection" ; rdfs:subClassOf obo:VO_0003421 . obo:VO_0003427 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658154" ; obo:VO_0003198 "1658154" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection" ; rdfs:subClassOf obo:VO_0003421 . obo:VO_0003428 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799447" ; obo:VO_0003198 "1799447" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a 2000000000 UNT [Vivotif]" ; rdfs:subClassOf obo:VO_0003353 . obo:VO_0003429 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/807271" ; obo:VO_0003198 "807271" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML" ; rdfs:subClassOf obo:VO_0003455 . obo:VO_0003430 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1160325" ; obo:VO_0003198 "1160325" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injectable Product" ; rdfs:subClassOf obo:VO_0003433 . obo:VO_0003431 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798362" ; obo:VO_0003198 "798362" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML" ; rdfs:subClassOf obo:VO_0003433 . obo:VO_0003432 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798476" ; obo:VO_0003198 "798476" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003430 . obo:VO_0003433 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798361" ; obo:VO_0003198 "798361" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000052 ] . obo:VO_0003434 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/803362" ; obo:VO_0003198 "803362" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML" ; rdfs:subClassOf obo:VO_0003433 . obo:VO_0003435 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658057" ; obo:VO_0003198 "1658057" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 Injection" ; rdfs:subClassOf obo:VO_0003430 . obo:VO_0003436 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658065" ; obo:VO_0003198 "1658065" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injection" ; rdfs:subClassOf obo:VO_0003431 . obo:VO_0003437 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658058" ; obo:VO_0003198 "1658058" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injection" ; rdfs:subClassOf obo:VO_0003435 . obo:VO_0003438 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799445" ; obo:VO_0003198 "1799445" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a 2000000000 UNT" ; rdfs:subClassOf obo:VO_0003446 . obo:VO_0003439 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluzone Intradermal" ; rdfs:subClassOf obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003019 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003440 obo:IAO_0000115 "A trivalent influenza vaccine containing two strains of influenza A and one strain of influenza B for use in people 18 years to 64 years for use during the 2012-2013 season." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://www.news.sanofi.us/2014-12-12-Sanofi-Pasteur-Announces-FDA-Approval-of-Fluzone-R-Intradermal-Quadrivalent-Influenza-Vaccine-for-Adults" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluzone Intradermal Trivalent" ; rdfs:subClassOf obo:VO_0003439, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] . obo:VO_0003441 obo:IAO_0000115 "Meningococcal conjugate vaccine, which contains four of the most common types of meningococcal bacteria (serogroups A, C, W, and Y), is used to prevent infection caused by meningococcal bacteria." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.everydayhealth.com/drugs/meningococcal-conjugate-vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal conjugate vaccine" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000195, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ] . obo:VO_0003442 obo:IAO_0000115 "A DTaP vaccine used to keep up protection (immunity) against diphtheria, tetanus (lockjaw) and pertussis (whooping cough) in children and adults who have been vaccinated for these diseases in the past." ; obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.cdc.gov/mmwr/preview/mmwrhtml/00048610.htm" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Acel-Imune" ; rdfs:subClassOf obo:VO_0000943, obo:VO_0001214, [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003089 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0003443 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vi Polysaccharide vaccine" ; rdfs:subClassOf obo:VO_0000671, obo:VO_0001255 . obo:VO_0003444 obo:IAO_0000115 "This term was used by the USA VAERS system to indicate the source, which is foreign to USA here, of the vaccine." ; obo:IAO_0000119 "https://wonder.cdc.gov/wonder/help/vaers.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccine foreign to USA" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0003445 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/762598" ; obo:VO_0003198 "762598" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a 2000000000 UNT Delayed Release Oral Capsule" ; rdfs:subClassOf obo:VO_0003447 . obo:VO_0003446 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/762595" ; obo:VO_0003198 "762595" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a" ; rdfs:subClassOf obo:VO_0000487 . obo:VO_0003447 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/762597" ; obo:VO_0003198 "762597" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a Delayed Release Oral Capsule" ; rdfs:subClassOf obo:VO_0003449 . obo:VO_0003448 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1159372" ; obo:VO_0003198 "1159372" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a Pill" ; rdfs:subClassOf obo:VO_0000487 . obo:VO_0003449 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1159371" ; obo:VO_0003198 "1159371" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid Vaccine Live Ty21a Oral Product" ; rdfs:subClassOf obo:VO_0000487 . obo:VO_0003450 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1660921" ; obo:VO_0003198 "1660921" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0000200 . obo:VO_0003451 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1186748" ; obo:VO_0003198 "1186748" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Twinrix Injectable Product" ; rdfs:subClassOf obo:VO_0000113 . obo:VO_0003452 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1724009" ; obo:VO_0003198 "1724009" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML" ; rdfs:subClassOf obo:VO_0000200 . obo:VO_0003453 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657222" ; obo:VO_0003198 "1657222" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen" ; rdfs:subClassOf obo:VO_0015084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003675 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003681 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003693 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003698 ] . obo:VO_0003454 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798305" ; obo:VO_0003198 "798305" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated 13.4 UNT/ML" ; rdfs:subClassOf obo:VO_0003455 . obo:VO_0003455 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798304" ; obo:VO_0003198 "798304" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000508, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000015 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000029 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000064 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000082 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000084 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003456 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/801709" ; obo:VO_0003198 "801709" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated 50 UNT/ML" ; rdfs:subClassOf obo:VO_0003455 . obo:VO_0003457 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/807414" ; obo:VO_0003198 "807414" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated 25 UNT/ML" ; rdfs:subClassOf obo:VO_0003455 . obo:VO_0003458 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658102" ; obo:VO_0003198 "1658102" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Injection [Vaqta]" ; rdfs:subClassOf obo:VO_0003466 . obo:VO_0003459 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/802012" ; obo:VO_0003198 "802012" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine, Inactivated 50 UNT/ML [Vaqta]" ; rdfs:subClassOf obo:VO_0010745 . obo:VO_0003460 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/836636" ; obo:VO_0003198 "836636" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Prefilled Syringe [Vaqta]" ; rdfs:subClassOf obo:VO_0003465 . obo:VO_0003461 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658106" ; obo:VO_0003198 "1658106" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Injection [Vaqta]" ; rdfs:subClassOf obo:VO_0003466 . obo:VO_0003462 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1187568" ; obo:VO_0003198 "1187568" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaqta Injectable Product" ; rdfs:subClassOf obo:VO_0010745 . obo:VO_0003463 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/836634" ; obo:VO_0003198 "836634" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis A Vaccine, Inactivated 50 UNT/ML Prefilled Syringe [Vaqta]" ; rdfs:subClassOf obo:VO_0003465 . obo:VO_0003464 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/253174" ; obo:VO_0003198 "253174" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine, Inactivated" ; rdfs:subClassOf obo:VO_0000646 . obo:VO_0003465 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/836633" ; obo:VO_0003198 "836633" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine, Inactivated Prefilled Syringe [Vaqta]" ; rdfs:subClassOf obo:VO_0010745 . obo:VO_0003466 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658101" ; obo:VO_0003198 "1658101" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine, Inactivated Injection [Vaqta]" ; rdfs:subClassOf obo:VO_0003462 . obo:VO_0003467 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658099" ; obo:VO_0003198 "1658099" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine, Inactivated Injection" ; rdfs:subClassOf obo:VO_0003468 . obo:VO_0003468 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1160328" ; obo:VO_0003198 "1160328" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine, Inactivated Injectable Product" ; rdfs:subClassOf obo:VO_0003464 . obo:VO_0003469 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657223" ; obo:VO_0003198 "1657223" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003453 . obo:VO_0003470 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657224" ; obo:VO_0003198 "1657224" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen" ; rdfs:subClassOf obo:VO_0015085, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003616 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003675 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003693 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003698 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003763 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003806 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003886 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003910 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0015080 ] . obo:VO_0003471 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658709" ; obo:VO_0003198 "1658709" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.12 MG/ML" ; 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rdfs:subClassOf obo:VO_0003470 . obo:VO_0003475 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657130" ; obo:VO_0003198 "1657130" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/South Australia/55/2014 (H3N2) antigen" ; rdfs:subClassOf obo:VO_0015085, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003715 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003779 ] . obo:VO_0003476 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657132" ; obo:VO_0003198 "1657132" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003475 . obo:VO_0003477 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657127" ; obo:VO_0003198 "1657127" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen" ; rdfs:subClassOf obo:VO_0015084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003779 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003784 ] . obo:VO_0003478 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799398" ; obo:VO_0003198 "1799398" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003477 . obo:VO_0003479 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657226", "https://www.fludb.org/brc/fluStrainDetails.spg?strainName=B/Brisbane/60/2008&decorator=influenza" ; obo:VO_0003198 "1657226" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; 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owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003894 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003898 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003911 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003912 ] . obo:VO_0003480 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657227" ; obo:VO_0003198 "1657227" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003479 . obo:VO_0003481 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1664469" ; obo:VO_0003198 "1664469" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML" ; rdfs:subClassOf obo:VO_0003479 . obo:VO_0003482 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661110" ; obo:VO_0003198 "1661110" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003479 . obo:VO_0003483 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801177" ; obo:VO_0003198 "1801177" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003479 . obo:VO_0003484 obo:IAO_0000118 "vaccine against Neisseriales", "vaccine against Neisseriales bacterial infection" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Neisseriaceae" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neisseriales vaccine" ; rdfs:subClassOf obo:VO_0003532, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_206351 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_206351 ] . obo:VO_0003485 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1946982" ; obo:VO_0003198 "1946982" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML" ; rdfs:subClassOf obo:VO_0003479 . obo:VO_0003486 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657133" ; obo:VO_0003198 "1657133" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Utah/9/2014 antigen" ; rdfs:subClassOf obo:VO_0015086, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003779 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003784 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003791 ] . obo:VO_0003487 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657135" ; obo:VO_0003198 "1657135" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003486 . obo:VO_0003488 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657228" ; obo:VO_0003198 "1657228" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Phuket/3073/2013 antigen" ; rdfs:subClassOf obo:VO_0015086, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003616 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003627 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003638 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003649 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003675 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003693 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003698 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003703 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003708 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003715 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003744 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003745 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003751 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003757 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003763 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003767 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003773 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003806 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003807 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003808 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003820 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003886 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003898 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003903 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0015080 ] . obo:VO_0003489 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657229" ; obo:VO_0003198 "1657229" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003488 . obo:VO_0003490 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1660923" ; obo:VO_0003198 "1660923" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003488 . obo:VO_0003491 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658710" ; obo:VO_0003198 "1658710" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003488 . obo:VO_0003492 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1946983" ; obo:VO_0003198 "1946983" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML" ; rdfs:subClassOf obo:VO_0003488 . obo:VO_0003493 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1664470" ; obo:VO_0003198 "1664470" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML" ; rdfs:subClassOf obo:VO_0003488 . obo:VO_0003494 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Spirochaetes." ; obo:IAO_0000118 "vaccine against Spirochaetes" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Spirochaete" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Spirochaetes vaccine" ; rdfs:subClassOf obo:VO_0003553, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_136 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_136 ] . obo:VO_0003495 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:VO_0003198 """NOT IN RxNorm Empty Parent Term""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "influenza vaccines" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0003496 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1116738" ; obo:VO_0003198 "1116738" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated A-Christchurch-16-2010 NIB-74 (H1N1) (A-California-7-2009) strain" ; rdfs:subClassOf obo:VO_0003498 . obo:VO_0003497 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1303851" ; obo:VO_0003198 "1303851" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003499, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003579 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003611 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003874 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003878 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003882 ] . obo:VO_0003498 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:VO_0003198 """NOT IN RxNorm Empty Parent Term""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H1N1) Virus Vaccine" ; rdfs:subClassOf obo:VO_0003495 . obo:VO_0003499 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:VO_0003198 """NOT IN RxNorm Empty Parent Term""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H1N1)-like Virus" ; rdfs:subClassOf obo:VO_0003495 . obo:VO_0003500 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:VO_0003198 """NOT IN RxNorm Empty Parent Term""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H3N2)-like Virus" ; rdfs:subClassOf obo:VO_0003495 . obo:VO_0003501 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:VO_0003198 """NOT IN RxNorm Empty Parent Term""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A (H3N2) Virus Vaccine" ; rdfs:subClassOf obo:VO_0003495 . obo:VO_0003502 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1541617" ; obo:VO_0003198 "1541617" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus" ; rdfs:subClassOf obo:VO_0003500 . obo:VO_0003503 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1541618" ; obo:VO_0003198 "1541618" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-Texas-50-2012 (H3N2)-like virus 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003502 . obo:VO_0003504 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1005931" ; obo:VO_0003198 "1005931" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain" ; rdfs:subClassOf obo:VO_0003501 . obo:VO_0003505 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1005932" ; obo:VO_0003198 "1005932" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003504 . obo:VO_0003506 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1111368" ; obo:VO_0003198 "1111368" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated A-Victoria-210-2009 X-187 (H3N2) (A-Perth-16-2009) strain 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003504 . obo:VO_0003507 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1304122" ; obo:VO_0003198 "1304122" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003500, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003579 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003611 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003874 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003878 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003882 ] . obo:VO_0003508 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1304300" ; obo:VO_0003198 "1304300" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003507 . obo:VO_0003509 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1304309" ; obo:VO_0003198 "1304309" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003507 . obo:VO_0003510 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1304123" ; obo:VO_0003198 "1304123" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003507 . obo:VO_0003511 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1303851" ; obo:VO_0003198 "1303851" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003497 . obo:VO_0003512 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1304299" ; obo:VO_0003198 "1304299" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003497 . obo:VO_0003513 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1304308" ; obo:VO_0003198 "1304308" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003497 . obo:VO_0003514 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1005929" ; obo:VO_0003198 "1005929" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain" ; rdfs:subClassOf obo:VO_0003498 . obo:VO_0003515 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1005930" ; obo:VO_0003198 "1005930" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003514 . obo:VO_0003516 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1111367" ; obo:VO_0003198 "1111367" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated A-California-07-2009 X-179A (H1N1) strain 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003514 . obo:VO_0003517 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1006250" ; obo:VO_0003198 "1006250" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated A-California-07-2009 X-181 (H1N1) strain" ; rdfs:subClassOf obo:VO_0003498 . obo:VO_0003518 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Borreliella." ; obo:IAO_0000118 "vaccine against Borreliella" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Borrelia" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Borreliella vaccine" ; rdfs:subClassOf obo:VO_0003494, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_64895 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_64895 ] . obo:VO_0003519 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:VO_0003198 """NOT IN RxNorm Empty Parent Term""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B Virus Vaccine" ; rdfs:subClassOf obo:VO_0003495 . obo:VO_0003520 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:VO_0003198 """NOT IN RxNorm Empty Parent Term""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B-like Virus" ; rdfs:subClassOf obo:VO_0003495 . obo:VO_0003521 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1303855" ; obo:VO_0003198 "1303855" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Wisconsin-1-2010-like virus" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003520, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003874 ] . obo:VO_0003522 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1304310" ; obo:VO_0003198 "1304310" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003521 . obo:VO_0003523 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/857921" ; obo:VO_0003198 "857921" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza Virus Vaccine, Inactivated B-Brisbane-60-2008" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003519, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003579 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003611 ] . obo:VO_0003524 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/857922" ; obo:VO_0003198 "857922" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003523 . obo:VO_0003525 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1111369" ; obo:VO_0003198 "1111369" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003523 . obo:VO_0003526 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1427022" ; obo:VO_0003198 "1427022" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003520, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003579 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003611 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003878 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003882 ] . obo:VO_0003527 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1427023" ; obo:VO_0003198 "1427023" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003526 . obo:VO_0003528 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1429576" ; obo:VO_0003198 "1429576" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003526 . obo:VO_0003529 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1429589" ; obo:VO_0003198 "1429589" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003526 . obo:VO_0003530 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1543760" ; obo:VO_0003198 "1543760" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 50000000 MG/ML" ; rdfs:subClassOf obo:VO_0003526 . obo:VO_0003531 obo:IAO_0000117 "Kallan Roan, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Proteobacteria vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1224 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1224 ] . obo:VO_0003532 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Betaproteobacteria vaccine" ; rdfs:subClassOf obo:VO_0003531, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28216 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28216 ] . obo:VO_0003533 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Yersiniaceae." ; obo:IAO_0000118 "vacccine against Yersiniaceae" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Yersiniaceae" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yersiniaceae vaccine" ; rdfs:subClassOf obo:VO_0003551, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1903411 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1903411 ] . obo:VO_0003534 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Corynebacterium." ; obo:IAO_0000118 "vaccine against Corynebacterium" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Corynebacterium" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Corynebacterium vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1716 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1716 ] . obo:VO_0003535 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Gammaproteobacteria vaccine" ; rdfs:subClassOf obo:VO_0003531, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1236 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1236 ] . obo:VO_0003536 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Bacillus." ; obo:IAO_0000118 "vaccine against Bacillus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Bacillus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bacillus vaccine" ; rdfs:subClassOf obo:VO_0003555, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1386 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1386 ] . obo:VO_0003537 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Varicellovirus." ; obo:IAO_0000118 "vaccine against Varicellovirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Varicellovirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicellovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10319 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10319 ] . obo:VO_0003538 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Papillomaviridae." ; obo:IAO_0000118 "vaccine against Papillomaviridae" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Papillomaviridae" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Papillomaviridae vaccine" ; rdfs:subClassOf obo:VO_0000586, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_151340 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_151340 ] . obo:VO_0003539 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Orthopoxvirus." ; obo:IAO_0000118 "vaccine against Orthopoxvirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Orthopoxvirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Orthopoxvirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10242 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10242 ] . obo:VO_0003540 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Orthohepadnavirus." ; obo:IAO_0000118 "vaccine against Orthohepadnavirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Orthohepadnavirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Orthohepadnavirus vaccine" ; rdfs:subClassOf obo:VO_0000586, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10405 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10405 ] . obo:VO_0003541 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Reoviridae." ; obo:IAO_0000118 "vaccine against Reoviridae" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Reoviridae" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Reoviridae vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2732541 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2732541 ] . obo:VO_0003542 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Sedoreovirinae." ; obo:IAO_0000118 "vaccine against Sedoreovirinae" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Sedoreovirinae" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Sedoreovirinae vaccine" ; rdfs:subClassOf obo:VO_0003541, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2946186 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2946186 ] . obo:VO_0003543 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Morbillivirus." ; obo:IAO_0000118 "vaccine against Morbillivirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Morbillivirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Morbillivirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11229 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11229 ] . obo:VO_0003544 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Rubulavirus." ; obo:IAO_0000118 "vaccine against Rubulavirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Rubulavirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rubulavirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_39744 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_39744 ] . obo:VO_0003545 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Lyssavirus." ; obo:IAO_0000118 "vaccine against Lyssavirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Lyssavirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lyssavirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11286 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11286 ] . obo:VO_0003546 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Flaviviridae." ; obo:IAO_0000118 "vaccine against Flaviviridae" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Flaviviridae" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Flaviviridae vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11050 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11050 ] . obo:VO_0003547 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Enterovirus." ; obo:IAO_0000118 "vaccine against Enterovirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Enterovirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Enterovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12059 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12059 ] . obo:VO_0003548 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Hepatovirus." ; obo:IAO_0000118 "vaccine against Hepatovirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Hepatitis_A#Virology" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12091 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12091 ] . obo:VO_0003549 obo:IAO_0000115 "A vaccine that is used against an infection by a pathogen under Rubivirus." ; obo:IAO_0000118 "vaccine against Rubivirus" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Rubella_virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rubivirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11040 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11040 ] . obo:VO_0003550 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Alphaproteobacteria vaccine" ; rdfs:subClassOf obo:VO_0003531, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28211 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28211 ] . obo:VO_0003551 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Enterobacterales vaccine" ; rdfs:subClassOf obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_91347 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_91347 ] . obo:VO_0003552 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Enterobacteriaceae vaccine" ; rdfs:subClassOf obo:VO_0003551, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_543 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_543 ] . obo:VO_0003553 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Spirochaetia vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_203692 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_203692 ] . obo:VO_0003554 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Firmicutes vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1239 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1239 ] . obo:VO_0003555 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bacilli vaccine" ; rdfs:subClassOf obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_91061 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_91061 ] . obo:VO_0003556 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lactobacillales vaccine" ; rdfs:subClassOf obo:VO_0003554 . obo:VO_0003557 a owl:AnnotationProperty ; rdfs:label "has Protegen id" . obo:VO_0003558 a owl:AnnotationProperty ; rdfs:label "has Protegen annotation" . obo:VO_0003559 obo:IAO_0000118 "Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901644" ; obo:VO_0003198 "901644" ; obo:VO_0003560 "0.5 ML Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0088 MG/ML / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML Prefilled Syringe [Prevnar 13]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Prevnar 13 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003570 . obo:VO_0003560 obo:IAO_0000112 "As seen: http://purl.bioontology.org/ontology/RXNORM/901644, the RxNORM vaccine term \"Prevnar 13 vaccine 0.5 ML Prefilled Syringe\" has Preferred Name of: 0.5 ML Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0088 MG/ML / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML Prefilled Syringe [Prevnar 13]\". In this case, the whole preferred name is annotated under the annotation property \"RxNORM Preferred Name\"." ; a owl:AnnotationProperty ; rdfs:label "RxNORM Preferred Name" . obo:VO_0003561 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854974" ; obo:VO_0003198 "854974" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 9V vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003562 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854975" ; obo:VO_0003198 "854975" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 9V vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003561 . obo:VO_0003563 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1182409" ; obo:VO_0003198 "1182409" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3236244", "RXAUI: 3843751", "RXN STRENGTH: 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML", "TUI: T200" ; rdfs:label "Pneumovax 23 Injectable Product" ; rdfs:subClassOf obo:VO_0000088 . obo:VO_0003564 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658471" ; obo:VO_0003198 "1658471" ; obo:VO_0003560 "pneumococcal capsular polysaccharide type 1 vaccine / pneumococcal capsular polysaccharide type 10A vaccine / pneumococcal capsular polysaccharide type 11A vaccine / pneumococcal capsular polysaccharide type 12F vaccine / pneumococcal capsular polysaccharide type 14 vaccine / pneumococcal capsular polysaccharide type 15B vaccine / pneumococcal capsular polysaccharide type 17F vaccine / pneumococcal capsular polysaccharide type 18C vaccine / pneumococcal capsular polysaccharide type 19A vaccine / pneumococcal capsular polysaccharide type 19F vaccine / pneumococcal capsular polysaccharide type 2 vaccine / pneumococcal capsular polysaccharide type 20 vaccine / pneumococcal capsular polysaccharide type 22F vaccine / pneumococcal capsular polysaccharide type 23F vaccine / pneumococcal capsular polysaccharide type 3 vaccine / pneumococcal capsular polysaccharide type 33F vaccine / pneumococcal capsular polysaccharide type 4 vaccine / pneumococcal capsular polysaccharide type 5 vaccine / pneumococcal capsular polysaccharide type 6B vaccine / pneumococcal capsular polysaccharide type 7F vaccine / pneumococcal capsular polysaccharide type 8 vaccine / pneumococcal capsular polysaccharide type 9N vaccine / pneumococcal capsular polysaccharide type 9V vaccine Injection [Pneumovax 23]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033793", "RXAUI: 7253076", "TUI: T200" ; rdfs:label "Pneumovax 23 Injection" ; rdfs:subClassOf obo:VO_0003563 . obo:VO_0003565 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Pneumovax 23 (Pneumococcal vaccine polyvalent) 0.5 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658472" ; obo:VO_0003198 "1658472" ; obo:VO_0003560 "0.5 ML pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 10A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 11A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 12F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 14 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 15B vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 17F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 18C vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 19A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 19F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 2 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 20 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 22F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 23F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 3 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 33F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 4 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 5 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 6B vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 7F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 8 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 9N vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 9V vaccine 0.05 MG/ML Injection [Pneumovax 23]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3887855", "RXAUI: 7253077, 7253108, 7253095", "RXN STRENGTH: 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML", "TUI: T200" ; rdfs:label "PNEUMOVAX 23 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003564, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003575 ] . obo:VO_0003566 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Pneumovax 23 (Pneumococcal vaccine polyvalent) Injectable Solution" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854981" ; obo:VO_0003198 "854981" ; obo:VO_0003560 "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 10A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 11A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 12F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 14 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 15B vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 17F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 18C vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 19A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 19F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 2 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 20 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 22F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 23F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 3 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 33F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 4 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 5 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 6B vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 7F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 8 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 9N vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 9V vaccine 0.05 MG/ML Injectable Solution [Pneumovax 23]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1154308", "RXAUI: 2977679, 7253371, 3270831", "RXN STRENGTH: 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML / 0.05 MG/ML", "TUI: T200" ; rdfs:label "PNEUMOVAX 23 vaccine Injectable Solution" ; rdfs:subClassOf obo:VO_0003563, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003575 ] . obo:VO_0003567 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1547581" ; obo:VO_0003198 "1547581" ; obo:VO_0003560 "pneumococcal capsular polysaccharide type 1 vaccine / pneumococcal capsular polysaccharide type 10A vaccine / pneumococcal capsular polysaccharide type 11A vaccine / pneumococcal capsular polysaccharide type 12F vaccine / pneumococcal capsular polysaccharide type 14 vaccine / pneumococcal capsular polysaccharide type 15B vaccine / pneumococcal capsular polysaccharide type 17F vaccine / pneumococcal capsular polysaccharide type 18C vaccine / pneumococcal capsular polysaccharide type 19A vaccine / pneumococcal capsular polysaccharide type 19F vaccine / pneumococcal capsular polysaccharide type 2 vaccine / pneumococcal capsular polysaccharide type 20 vaccine / pneumococcal capsular polysaccharide type 22F vaccine / pneumococcal capsular polysaccharide type 23F vaccine / pneumococcal capsular polysaccharide type 3 vaccine / pneumococcal capsular polysaccharide type 33F vaccine / pneumococcal capsular polysaccharide type 4 vaccine / pneumococcal capsular polysaccharide type 5 vaccine / pneumococcal capsular polysaccharide type 6B vaccine / pneumococcal capsular polysaccharide type 7F vaccine / pneumococcal capsular polysaccharide type 8 vaccine / pneumococcal capsular polysaccharide type 9N vaccine / pneumococcal capsular polysaccharide type 9V vaccine Prefilled Syringe [Pneumovax 23]" ; 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rdfs:label "Prevnar 13 Injectable Product" ; rdfs:subClassOf obo:VO_0001244 . obo:VO_0003570 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901643" ; obo:VO_0003198 "901643" ; obo:VO_0003560 "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine Prefilled Syringe [Prevnar 13]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2746125", "RXAUI: 3060990", "TUI: T200" ; rdfs:label "Prevnar 13 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003569 . obo:VO_0003571 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854967" ; obo:VO_0003198 "854967" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2709771", "RXAUI: 2977666" ; rdfs:label "pneumococcal capsular polysaccharide type 6B vaccine 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003250 . obo:VO_0003572 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1179526" ; obo:VO_0003198 "1179526" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3233397", "RXAUI: 3844185", "TUI: T200" ; rdfs:label "ProQuad Injectable Product" ; rdfs:subClassOf obo:VO_0000091 . obo:VO_0003573 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658000" ; obo:VO_0003198 "1658000" ; obo:VO_0003560 "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain / Mumps Virus Vaccine Live, Jeryl Lynn Strain / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain Injection [ProQuad]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033818", "RXAUI: 7252149", "TUI: T200" ; rdfs:label "ProQuad vaccine Injection" ; rdfs:subClassOf obo:VO_0003572 . obo:VO_0003574 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "ProQuad Measles, Mumps, Rubella, and Varicella Virus Vaccine Live 0.5 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292443" ; obo:VO_0003198 "1292443" ; obo:VO_0003560 "0.5 ML Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 40000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 20000 UNT/ML Injection [ProQuad]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1698231", "RXAUI: 7252150, 7250950, 7253644", "TUI: T200" ; rdfs:label "ProQuad vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003573, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003278 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015055 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015057 ] . obo:VO_0003575 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854979" ; obo:VO_0003198 "854979" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2709781", "RXAUI: 2977677", "TUI: T200" ; rdfs:label "pneumococcal capsular polysaccharide type 1 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 10A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 11A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 12F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 14 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 15B vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 17F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 18C vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 19A vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 19F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 2 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 20 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 22F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 23F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 3 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 33F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 4 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 5 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 6B vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 7F vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 8 vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 9N vaccine 0.05 MG/ML / pneumococcal capsular polysaccharide type 9V vaccine 0.05 MG/ML [Pneumovax 23]" ; 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owl:someValuesFrom obo:VO_0003322 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003323 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003324 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003325 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003326 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003327 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003328 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003329 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003330 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003331 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003332 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003562 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003571 ] . obo:VO_0003576 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901642" ; obo:VO_0003198 "901642" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2746124", "RXAUI: 3060989", "TUI: T200" ; rdfs:label "Streptococcus pneumoniae serotype 1 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 14 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 18C capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 19F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 23F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 3 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 4 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 5 capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6A capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 6B capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0088 MG/ML / Streptococcus pneumoniae serotype 7F capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML / Streptococcus pneumoniae serotype 9V capsular antigen diphtheria CRM197 protein conjugate vaccine 0.0044 MG/ML [Prevnar 13]" ; rdfs:subClassOf obo:VO_0001244, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003286 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003287 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003288 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003289 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003290 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003291 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003292 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003293 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003294 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003295 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003296 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003297 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003298 ] . obo:VO_0003577 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292441" ; obo:VO_0003198 "1292441" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364511", "RXAUI: 4609906", "TUI: T200" ; rdfs:label "Measles Virus Vaccine Live, Enders' attenuated Edmonston strain 2000 UNT/ML / Mumps Virus Vaccine Live, Jeryl Lynn Strain 40000 UNT/ML / Rubella Virus Vaccine Live (Wistar RA 27-3 Strain) 2000 UNT/ML / Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 20000 UNT/ML [ProQuad]" ; rdfs:subClassOf obo:VO_0000091, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003278 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015055 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015057 ] . obo:VO_0003578 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658703" ; obo:VO_0003198 "1658703" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033722", "RXAUI: 7253467", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone 2015-2016]" ; rdfs:subClassOf obo:VO_0015080, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003472 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ] . obo:VO_0003579 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1427028" ; obo:VO_0003198 "1427028" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3645245", "RXAUI: 5473440", "TUI: T116, T121" ; rdfs:label "Fluzone Quadrivalent 2013-2014 Formula" ; rdfs:subClassOf obo:VO_0003073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003497 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003507 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003523 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003526 ] . obo:VO_0003580 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658712" ; obo:VO_0003198 "1658712" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033721", "RXAUI: 7253478", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.12 MG/ML [Fluzone 2015-2016]" ; rdfs:subClassOf obo:VO_0015080, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003260 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003471 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003491 ] . obo:VO_0003581 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658713" ; obo:VO_0003198 "1658713" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033789", "RXAUI: 7253479", "TUI: T200" ; rdfs:label "Fluzone 2015-2016 High-Dose vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0000079, obo:VO_0015081 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000079 obo:VO_0015081 ) ] . obo:VO_0003582 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658714" ; obo:VO_0003198 "1658714" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026367", "RXAUI: 7253480, 7253494, 7707297", "TUI: T200" ; rdfs:label "Fluzone 2015-2016 High-Dose vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003581, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003260 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003471 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003491 ] . obo:VO_0003583 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Fluzone 2015-2016 45 MCG (15 MCG x 3) in 0.5 ML Injectable Suspension", "http://purl.bioontology.org/ontology/RXNORM/1658706" ; obo:VO_0003198 "1658706" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033789", "RXAUI: 7264732, 7253470, 7264735", "TUI: T200" ; rdfs:label "Fluzone 2015-2016 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0015081 . obo:VO_0003584 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801179" ; obo:VO_0003198 "1801179" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271565", "RXAUI: 8237155", "TUI: T116, T129, T121" ; rdfs:label "Fluzone 2016-2017" ; rdfs:subClassOf obo:VO_0000047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003585 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801180" ; obo:VO_0003198 "1801180" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271631", "RXAUI: 8237156", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML [Fluzone 2016-2017]" ; rdfs:subClassOf obo:VO_0003584, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003260 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003483 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003606 ] . obo:VO_0003586 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801182" ; obo:VO_0003198 "1801182" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271735", "RXAUI: 8237158", "TUI: T200" ; rdfs:label "Fluzone 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003584 . obo:VO_0003587 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801181" ; obo:VO_0003198 "1801181" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271674", "RXAUI: 8237157", "TUI: T200" ; rdfs:label "Fluzone 2016-2017 High-Dose vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0000079, obo:VO_0003586 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000079 obo:VO_0003586 ) ] . obo:VO_0003588 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801183" ; obo:VO_0003198 "1801183" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4270825", "RXAUI: 8237163, 8237162, 8237159", "TUI: T200" ; rdfs:label "Fluzone 2016-2017 High-Dose vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003587, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003260 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003483 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003606 ] . obo:VO_0003589 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928340" ; obo:VO_0003198 "1928340" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490427", "RXAUI: 9198824", "TUI: T116" ; rdfs:label "Fluzone 2017-2018" ; rdfs:subClassOf obo:VO_0000047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003600 ] . obo:VO_0003590 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928343" ; obo:VO_0003198 "1928343" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490430", "RXAUI: 9198827", "TUI: T200" ; rdfs:label "Fluzone 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003589 . obo:VO_0003591 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928341" ; obo:VO_0003198 "1928341" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490428", "RXAUI: 9198825", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML [Fluzone 2017-2018]" ; rdfs:subClassOf obo:VO_0003589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003483 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003604 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003606 ] . obo:VO_0003592 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928342" ; obo:VO_0003198 "1928342" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490429", "RXAUI: 9198826", "TUI: T200" ; rdfs:label "Fluzone 2017-2018 high-dose vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0000079, obo:VO_0003590 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000079 obo:VO_0003590 ) ] . obo:VO_0003593 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928344" ; obo:VO_0003198 "1928344" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325062", "RXAUI: 9198828, 9198831, 9198832", "TUI: T200" ; rdfs:label "Fluzone 2017-2018 high-dose vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003592, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003483 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003604 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003606 ] . obo:VO_0003594 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050419" ; obo:VO_0003198 "2050419" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719042", "RXAUI: 10289780", "TUI: T109" ; rdfs:label "Fluzone 2018-2019" ; rdfs:subClassOf obo:VO_0000047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003600 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003602 ] . obo:VO_0003595 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050422" ; obo:VO_0003198 "2050422" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719045", "RXAUI: 10289783", "RXN STRENGTH: 0.12 MG/ML (expressed as influenza A virus A/Michigan/45/2015 (H1N1) antigen) / 0.12 MG/ML (expressed as influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen) / 0.12 MG/ML (expressed as influenza B virus B/Maryland/15/2016 antigen)", "TUI: T200" ; rdfs:label "Fluzone 2018-2019 Injectable Product" ; rdfs:subClassOf obo:VO_0003594 . obo:VO_0003596 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050420" ; obo:VO_0003198 "2050420" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719043", "RXAUI: 10289781", "TUI: T200" ; rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML [Fluzone 2018-2019]" ; rdfs:subClassOf obo:VO_0003594, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003603 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003604 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003605 ] . obo:VO_0003597 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050421" ; obo:VO_0003198 "2050421" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719044", "RXAUI: 10289782", "TUI: T200" ; rdfs:label "Fluzone 2018-2019 high-dose vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0000079, obo:VO_0003595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003603 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003604 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000079 obo:VO_0003595 ) ] . obo:VO_0003598 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050423" ; obo:VO_0003198 "2050423" ; obo:VO_0003560 "0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML Prefilled Syringe [Fluzone 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719046", "RXAUI: 10289784, 10289785, 10289786", "TUI: T200" ; rdfs:label "Fluzone 2018-2019 high-dose vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003597 . obo:VO_0003599 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1794331" ; obo:VO_0003198 "1794331" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4256803", "RXAUI: 8222490", "TUI: T116, T129, T121" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen" ; rdfs:subClassOf obo:VO_0015085, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003584 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003589 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003627 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003638 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003681 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003687 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003698 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003703 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003721 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003727 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003744 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003745 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003757 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003767 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003784 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003890 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003894 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003898 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003911 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003912 ] . obo:VO_0003600 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928289" ; obo:VO_0003198 "1928289" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4490394", "RXAUI: 9198755", "TUI: T116, T129, T121" ; rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen" ; rdfs:subClassOf obo:VO_0015084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003589 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003594 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003638 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003649 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003894 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003898 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003903 ] . obo:VO_0003601 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048564" ; obo:VO_0003198 "2048564" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4704008", "RXAUI: 10279285", "TUI: T116, T129, T121" ; rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen" ; rdfs:subClassOf obo:VO_0015085, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003594 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003649 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003687 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003708 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003733 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003751 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003773 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003791 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003820 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003903 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003913 ] . obo:VO_0003602 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048563" ; obo:VO_0003198 "2048563" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4704007", "RXAUI: 10279284", "TUI: T116, T129, T121" ; rdfs:label "influenza B virus B/Maryland/15/2016 antigen" ; rdfs:subClassOf obo:VO_0015086, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003594 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003649 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003708 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003733 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003751 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003773 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003903 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003913 ] . obo:VO_0003603 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050417" ; obo:VO_0003198 "2050417" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4719040", "RXAUI: 10289778", "RXN STRENGTH: 0.12 MG/ML", "TUI: T200" ; rdfs:label "influenza B virus B/Maryland/15/2016 antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003602 . obo:VO_0003604 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928338" ; obo:VO_0003198 "1928338" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4490425", "RXAUI: 9198822", "RXN STRENGTH: 0.12 MG/ML", "TUI: T200" ; rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003600 . obo:VO_0003605 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050416" ; obo:VO_0003198 "2050416" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4719039", "RXAUI: 10289777", "RXN STRENGTH: 0.12 MG/ML", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003601 . obo:VO_0003606 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801176" ; obo:VO_0003198 "1801176" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4271783", "RXAUI: 8237152", "RXN STRENGTH: 0.12 MG/ML", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.12 MG/ML" ; rdfs:subClassOf obo:VO_0003599 . obo:VO_0003607 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1427031" ; obo:VO_0003198 "1427031" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3645248", "RXAUI: 5473443", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2013-2014 Formula Injectable Product" ; rdfs:subClassOf obo:VO_0003579 . obo:VO_0003608 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1427029" ; obo:VO_0003198 "1427029" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3645246", "RXAUI: 5473441", "TUI: T200" ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.03 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / Influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.03 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML [Fluzone Quadrivalent 2013-2014 Formula]" ; rdfs:subClassOf obo:VO_0003579, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003510 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003511 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003524 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003527 ] . obo:VO_0003609 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1427038" ; obo:VO_0003198 "1427038" ; obo:VO_0003560 "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Brisbane-60-2008-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone Quadrivalent 2013-2014 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3645252", "RXAUI: 5473453", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2013-2014 Formula Influenza Virus Vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003607 . obo:VO_0003610 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1427052" ; obo:VO_0003198 "1427052" ; obo:VO_0003560 "0.25 ML Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.03 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.03 MG/ML / Influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.03 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2013-2014 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3537276", "RXAUI: 5488148, 5473470, 5473464", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2013-2014 Formula Influenza Virus Vaccine 0.25 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003510 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003511 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003524 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003527 ] . obo:VO_0003611 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1537557" ; obo:VO_0003198 "1537557" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3817309", "RXAUI: 6338534", "TUI: T116, T121" ; rdfs:label "Fluzone Quadrivalent 2014-2015 Formula" ; rdfs:subClassOf obo:VO_0003073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003497 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003507 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003523 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003526 ] . obo:VO_0003612 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1537560" ; obo:VO_0003198 "1537560" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3819823", "RXAUI: 6338537", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2014-2015 Formula Injectable Product" ; rdfs:subClassOf obo:VO_0003611 . obo:VO_0003613 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1598360" ; obo:VO_0003198 "1598360" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3872179", "RXAUI: 6821895", "TUI: T200" ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML [Fluzone Quadrivalent 2014-2015 Formula]" ; rdfs:subClassOf obo:VO_0003611, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003509 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003513 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003525 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003528 ] . obo:VO_0003614 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1537559" ; obo:VO_0003198 "1537559" ; obo:VO_0003560 "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus / Influenza B virus vaccine, B-Brisbane-60-2008-like virus / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus Prefilled Syringe [Fluzone Quadrivalent 2014-2015 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3819658", "RXAUI: 6338536", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2014-2015 Formula Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003612 . obo:VO_0003615 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1598361" ; obo:VO_0003198 "1598361" ; obo:VO_0003560 "0.1 ML Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Brisbane-60-2008-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2014-2015 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3871481", "RXAUI: 6821896, 6821899", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2014-2015 Formula 0.1 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003614, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003613 ] . obo:VO_0003616 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659725" ; obo:VO_0003198 "1659725" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026655", "RXAUI: 7255357", "TUI: T116, T129, T121" ; rdfs:label "Fluzone Quadrivalent 2015-2016" ; rdfs:subClassOf obo:VO_0003073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003470 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ] . obo:VO_0003617 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659728" ; obo:VO_0003198 "1659728" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4047088", "RXAUI: 7255360", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0003616 . obo:VO_0003618 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659726" ; obo:VO_0003198 "1659726" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4046959", "RXAUI: 7255358", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2015-2016]" ; rdfs:subClassOf obo:VO_0003616, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003472 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ] . obo:VO_0003619 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661112" ; obo:VO_0003198 "1661112" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4046937", "RXAUI: 7258293", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Fluzone Quadrivalent 2015-2016]" ; rdfs:subClassOf obo:VO_0003616, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003450 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003482 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003490 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003658 ] . obo:VO_0003620 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659747" ; obo:VO_0003198 "1659747" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4047035", "RXAUI: 7255391", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2015-2016 Injection" ; rdfs:subClassOf obo:VO_0003617 . obo:VO_0003621 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659748" ; obo:VO_0003198 "1659748" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4046210", "RXAUI: 7255392, 7707326", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003618 ] . obo:VO_0003622 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659729" ; obo:VO_0003198 "1659729" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4018869", "RXAUI: 7707300, 7255361", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003617, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003618 ] . obo:VO_0003623 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659736" ; obo:VO_0003198 "1659736" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4047037", "RXAUI: 7255373", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003617 . obo:VO_0003624 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661113" ; obo:VO_0003198 "1661113" ; obo:VO_0003560 "0.1 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4032740", "RXAUI: 7707304, 7258294", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine 0.1 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003619 ] . obo:VO_0003625 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659755" ; obo:VO_0003198 "1659755" ; obo:VO_0003560 "0.25 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026368", "RXAUI: 7255401, 7707633", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine 0.25 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003618 ] . obo:VO_0003626 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659737" ; obo:VO_0003198 "1659737" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4046211", "RXAUI: 7707379, 7255374", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2015-2016 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003618 ] . obo:VO_0003627 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801071" ; obo:VO_0003198 "1801071" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224224", "RXAUI: 8236907", "TUI: T116, T129, T121" ; rdfs:label "Fluzone Quadrivalent 2016-2017" ; rdfs:subClassOf obo:VO_0003073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003628 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801074" ; obo:VO_0003198 "1801074" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271738", "RXAUI: 8236910", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003627 . obo:VO_0003629 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801173" ; obo:VO_0003198 "1801173" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271632", "RXAUI: 8237145", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2016-2017]" ; rdfs:subClassOf obo:VO_0003627, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ] . obo:VO_0003630 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801072" ; obo:VO_0003198 "1801072" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271637", "RXAUI: 8236908", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Fluzone Quadrivalent 2016-2017]" ; rdfs:subClassOf obo:VO_0003627, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003450 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003482 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003490 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003660 ] . obo:VO_0003631 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801188" ; obo:VO_0003198 "1801188" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271673", "RXAUI: 8237172", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2016-2017 Formula Injection" ; rdfs:subClassOf obo:VO_0003628 . obo:VO_0003632 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801189" ; obo:VO_0003198 "1801189" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4270930", "RXAUI: 8237177, 8237176, 8237173", "RXN STRENGTH: 0.03 MG/ML (expressed as influenza A virus A/California/7/2009 (H1N1) antigen) / 0.03 MG/ML (expressed as influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen) / 0.03 MG/ML (expressed as influenza B virus B/Brisbane/60/2008 antigen) / 0.03 MG/ML (expressed as influenza B virus B/Phuket/3073/2013 antigen)", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2016-2017 Formula 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003629 ] . obo:VO_0003633 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801193" ; obo:VO_0003198 "1801193" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224210", "RXAUI: 8237184, 8237186, 8237185", "RXN STRENGTH: 0.03 MG/ML (expressed as influenza A virus A/California/7/2009 (H1N1) antigen) / 0.03 MG/ML (expressed as influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen) / 0.03 MG/ML (expressed as influenza B virus B/Brisbane/60/2008 antigen) / 0.03 MG/ML (expressed as influenza B virus B/Phuket/3073/2013 antigen)", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2016-2017 Injectable Suspension" ; rdfs:subClassOf obo:VO_0003628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003629 ] . obo:VO_0003634 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801073" ; obo:VO_0003198 "1801073" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271678", "RXAUI: 8236909", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003628 . obo:VO_0003635 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801075" ; obo:VO_0003198 "1801075" ; obo:VO_0003560 "0.1 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4270829", "RXAUI: 8236914, 8237166, 8236911", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine 0.1 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003634, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003630 ] . obo:VO_0003636 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801174" ; obo:VO_0003198 "1801174" ; obo:VO_0003560 "0.25 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224209", "RXAUI: 8237169, 8237148, 8237146", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine 0.25 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003634, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003629 ] . obo:VO_0003637 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801186" ; obo:VO_0003198 "1801186" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4270931", "RXAUI: 8237168, 8237167, 8237165", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2016-2017 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003634, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003629 ] . obo:VO_0003638 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928313" ; obo:VO_0003198 "1928313" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325215", "RXAUI: 9198781", "TUI: T116, T129, T121" ; rdfs:label "Fluzone Quadrivalent 2017-2018" ; rdfs:subClassOf obo:VO_0003073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003600 ] . obo:VO_0003639 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928316" ; obo:VO_0003198 "1928316" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490411", "RXAUI: 9198784", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003638 . obo:VO_0003640 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928314" ; obo:VO_0003198 "1928314" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490409", "RXAUI: 9198782", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2017-2018]" ; rdfs:subClassOf obo:VO_0003638, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003661 ] . obo:VO_0003641 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928469" ; obo:VO_0003198 "1928469" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490475", "RXAUI: 9199188", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Fluzone Quadrivalent 2017-2018]" ; rdfs:subClassOf obo:VO_0003638, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003482 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003490 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003660 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003662 ] . obo:VO_0003642 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928315" ; obo:VO_0003198 "1928315" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490410", "RXAUI: 9198783", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine Injection" ; rdfs:subClassOf obo:VO_0003639 . obo:VO_0003643 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928317" ; obo:VO_0003198 "1928317" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490412", "RXAUI: 9198785, 9198856, 9198855", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003642, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003640 ] . obo:VO_0003644 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928356" ; obo:VO_0003198 "1928356" ; obo:VO_0003560 "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4319521", "RXAUI: 9198884, 9198850, 9198885", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003639, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003640 ] . obo:VO_0003645 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928331" ; obo:VO_0003198 "1928331" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490420", "RXAUI: 9198810", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003639 . obo:VO_0003646 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928359" ; obo:VO_0003198 "1928359" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490439", "RXAUI: 9198872, 9198871, 9198873", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003645, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003640 ] . obo:VO_0003647 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928332" ; obo:VO_0003198 "1928332" ; obo:VO_0003560 "0.25 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325067", "RXAUI: 9198880, 9198881, 9198811", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine 0.25 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003645, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003640 ] . obo:VO_0003648 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928470" ; obo:VO_0003198 "1928470" ; obo:VO_0003560 "0.1 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325068", "RXAUI: 9199192, 9199191, 9199189", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2017-2018 vaccine 0.1 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003645, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003641 ] . obo:VO_0003649 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050773" ; obo:VO_0003198 "2050773" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719179", "RXAUI: 10290520", "TUI: T116, T129, T121" ; rdfs:label "Fluzone Quadrivalent 2018-2019" ; rdfs:subClassOf obo:VO_0003073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003600 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003602 ] . obo:VO_0003650 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050776" ; obo:VO_0003198 "2050776" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719182", "RXAUI: 10290523", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2018-2019 Injectable Product" ; rdfs:subClassOf obo:VO_0003649 . obo:VO_0003651 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050774" ; obo:VO_0003198 "2050774" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719180", "RXAUI: 10290521", "TUI: T200" ; rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluzone Quadrivalent 2018-2019]" ; rdfs:subClassOf obo:VO_0003649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003661 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003663 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003664 ] . obo:VO_0003652 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050781" ; obo:VO_0003198 "2050781" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Injection [Fluzone Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719187", "RXAUI: 10290530", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine Injection" ; rdfs:subClassOf obo:VO_0003650 . obo:VO_0003653 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050782" ; obo:VO_0003198 "2050782" ; obo:VO_0003560 "0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injection [Fluzone Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719188", "RXAUI: 10290531, 10290534, 10290535", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003652, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003651 ] . obo:VO_0003654 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050787" ; obo:VO_0003198 "2050787" ; obo:VO_0003560 "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluzone Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4553813", "RXAUI: 10290540, 10290538, 10290539", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003650, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003651 ] . obo:VO_0003655 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050775" ; obo:VO_0003198 "2050775" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluzone Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719181", "RXAUI: 10290522", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2018-2019 Vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003650 . obo:VO_0003656 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050789" ; obo:VO_0003198 "2050789" ; obo:VO_0003560 "0.25 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719194", "RXAUI: 10290543, 10290544, 10290545", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent Pediatric Dose for 6-35 Months of Age 2018-2019 Vaccine 0.25 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003655, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003651 ] . obo:VO_0003657 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050777" ; obo:VO_0003198 "2050777" ; obo:VO_0003560 "0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluzone Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "RXAUI: 10290524, 10290528, 10290527", "TUI: T200" ; rdfs:label "Fluzone Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003655, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003651 ] . obo:VO_0003658 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1660922" ; obo:VO_0003198 "1660922" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4047148", "RXAUI: 7258095", "TUI: T200" ; rdfs:label "influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003470 . obo:VO_0003659 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1794431" ; obo:VO_0003198 "1794431" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4257282", "RXAUI: 8222590", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003599 . obo:VO_0003660 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801069" ; obo:VO_0003198 "1801069" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4271787", "RXAUI: 8236905", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003599 . obo:VO_0003661 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928310" ; obo:VO_0003198 "1928310" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4490406", "RXAUI: 9198778", "TUI: T200" ; rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003600 . obo:VO_0003662 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928291" ; obo:VO_0003198 "1928291" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4490396", "RXAUI: 9198757", "TUI: T200" ; rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003600 . obo:VO_0003663 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048958" ; obo:VO_0003198 "2048958" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4704185", "RXAUI: 10279935", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003601 . obo:VO_0003664 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048959" ; obo:VO_0003198 "2048959" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4704186", "RXAUI: 10279936", "TUI: T200" ; rdfs:label "influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003602 . obo:VO_0003665 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "RXAUI: 3850144", "http://purl.bioontology.org/ontology/RXNORM/1186641" ; obo:VO_0003198 "1186641" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3240393", "TUI: T200" ; rdfs:label "YF-Vax Injectable Product" ; rdfs:subClassOf obo:VO_0000121 . obo:VO_0003666 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:VO_0003198 "1658240" ; obo:VO_0003560 "Yellow-Fever Virus Vaccine, 17D-204 strain Injection [YF-Vax]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033799", "RXAUI: 7252581", "TUI: T200" ; rdfs:label "YF-VAX Injection" ; rdfs:subClassOf obo:VO_0003665 . obo:VO_0003667 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "0.5 ML YF-Vax 4000 UNT/ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658241" ; obo:VO_0003198 "1658241" ; obo:VO_0003560 "0.5 ML Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML Injection [YF-Vax]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4019051", "RXAUI: 7252591, 7252583, 7252590, 7252582", "TUI: T200" ; rdfs:label "YF-VAX 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003666, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003381 ] . obo:VO_0003668 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292828" ; obo:VO_0003198 "1292828" ; obo:VO_0003560 "YF-Vax 4000 UNT/ML Injectable Suspension" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0710788", "RXAUI: 4610776, 4610775, 7251861", "TUI: T200" ; rdfs:label "YF-Vax 4000 UNT/ML Injectable Suspension" ; rdfs:subClassOf obo:VO_0003669, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003381 ] . obo:VO_0003669 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292827" ; obo:VO_0003198 "1292827" ; obo:VO_0003560 "Yellow-Fever Virus Vaccine, 17D-204 strain Injectable Suspension [YF-Vax]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2356379", "RXAUI: 4610774", "TUI: T200" ; rdfs:label "YF-Vax Injectable Suspension" ; rdfs:subClassOf obo:VO_0003665 . obo:VO_0003670 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/804191" ; obo:VO_0003198 "804191" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2356378", "RXAUI: 2860284", "TUI: T200" ; rdfs:label "Yellow-Fever Virus Vaccine, 17D-204 strain 4000 UNT/ML [YF-Vax]" ; rdfs:subClassOf obo:VO_0003665, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003381 ] . obo:VO_0003671 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1184551" ; obo:VO_0003198 "1184551" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3238354", "RXAUI: 3843231", "TUI: T200" ; rdfs:label "PedvaxHIB Injectable Product" ; rdfs:subClassOf obo:VO_0000083 . obo:VO_0003672 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798449" ; obo:VO_0003198 "798449" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344386", "RXAUI: 2851572", "TUI: T200" ; rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML [PedvaxHIB]" ; rdfs:subClassOf obo:VO_0000083 . obo:VO_0003673 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657733" ; obo:VO_0003198 "1657733" ; obo:VO_0003560 "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine Injection [PedvaxHIB]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033832", "RXAUI: 7251648", "TUI: T200" ; rdfs:label "PedvaxHIB vaccine Injection" ; rdfs:subClassOf obo:VO_0003671 . obo:VO_0003674 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798451" ; obo:VO_0003198 "798451" ; obo:VO_0003560 "0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML Injection [PedvaxHIB]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1237239", "RXAUI: 7251650, 7251649, 7253595, 7251196", "TUI: T200" ; rdfs:label "PedvaxHIB vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003673, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003413 ] . obo:VO_0003675 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657326" ; obo:VO_0003198 "1657326" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026630", "RXAUI: 7251220", "TUI: T116, T129, T121" ; rdfs:label "Fluvirin 2015-2016" ; rdfs:subClassOf obo:VO_0000046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003453 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003470 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ] . obo:VO_0003676 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657329" ; obo:VO_0003198 "1657329" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033912", "RXAUI: 7251223", "TUI: T200" ; rdfs:label "Fluvirin 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0003675 . obo:VO_0003677 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657327" ; obo:VO_0003198 "1657327" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033751", "RXAUI: 7251221", "TUI: T200" ; rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluvirin 2015-2016]" ; rdfs:subClassOf obo:VO_0003675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003469 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003472 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ] . obo:VO_0003678 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657330" ; obo:VO_0003198 "1657330" ; obo:VO_0003560 "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Fluvirin 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026364", "RXAUI: 7251224, 7251264", "TUI: T200" ; rdfs:label "Fluvirin 2015-2016 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003676, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003677 ] . obo:VO_0003679 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659982" ; obo:VO_0003198 "1659982" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluvirin 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4047024", "RXAUI: 7255800", "TUI: T200" ; rdfs:label "Fluvirin 2015-2016 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003676 . obo:VO_0003680 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659983" ; obo:VO_0003198 "1659983" ; obo:VO_0003560 "0.5 ML influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluvirin 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026365", "RXAUI: 7255801, 7255804", "TUI: T200" ; rdfs:label "Fluvirin 2015-2016 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003679, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003677 ] . obo:VO_0003681 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801153" ; obo:VO_0003198 "1801153" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224219", "RXAUI: 8237127", "TUI: T116, T129, T121" ; rdfs:label "Fluvirin 2016-2017" ; rdfs:subClassOf obo:VO_0000046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003453 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003682 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801156" ; obo:VO_0003198 "1801156" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271736", "RXAUI: 8237130", "TUI: T200" ; rdfs:label "Fluvirin 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003681 . obo:VO_0003683 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801154" ; obo:VO_0003198 "1801154" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271633", "RXAUI: 8237128", "TUI: T200" ; rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluvirin 2016-2017]" ; rdfs:subClassOf obo:VO_0003681, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003469 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ] . obo:VO_0003684 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801157" ; obo:VO_0003198 "1801157" ; obo:VO_0003560 "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Injectable Suspension [Fluvirin 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224195", "RXAUI: 8237131, 8237133, 8237132", "TUI: T200" ; rdfs:label "Fluvirin 2016-2017 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003682, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003683 ] . obo:VO_0003685 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801162" ; obo:VO_0003198 "1801162" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluvirin 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271675", "RXAUI: 8237137", "TUI: T200" ; rdfs:label "Fluvirin 2016-2017 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003682 . obo:VO_0003686 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801163" ; obo:VO_0003198 "1801163" ; obo:VO_0003560 "0.5 ML influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Fluvirin 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4270826", "RXAUI: 8237141, 8237142, 8237138", "TUI: T200" ; rdfs:label "Fluvirin 2016-2017 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003685, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003683 ] . obo:VO_0003687 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928970" ; obo:VO_0003198 "1928970" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325210", "RXAUI: 9199995", "TUI: T116, T129, T121" ; rdfs:label "Fluvirin 2017-2018" ; rdfs:subClassOf obo:VO_0000046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ] . obo:VO_0003688 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928973" ; obo:VO_0003198 "1928973" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490746", "RXAUI: 9199998", "TUI: T200" ; rdfs:label "Fluvirin 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003687 . obo:VO_0003689 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928971" ; obo:VO_0003198 "1928971" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490744", "RXAUI: 9199996", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluvirin 2017-2018]" ; rdfs:subClassOf obo:VO_0003687, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003663 ] . obo:VO_0003690 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928974" ; obo:VO_0003198 "1928974" ; obo:VO_0003560 "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Injectable Suspension [Fluvirin 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325059", "RXAUI: 9200000, 9199999, 9200001", "TUI: T200" ; rdfs:label "Fluvirin 2017-2018 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003688, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003689 ] . obo:VO_0003691 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928978" ; obo:VO_0003198 "1928978" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluvirin 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490747", "RXAUI: 9200007", "TUI: T200" ; rdfs:label "Fluvirin 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003688 . obo:VO_0003692 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928982" ; obo:VO_0003198 "1928982" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Fluvirin 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325061", "RXAUI: 9200013, 9200018, 9200017", "TUI: T200" ; rdfs:label "Fluvirin 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003691, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003689 ] . obo:VO_0003693 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657232" ; obo:VO_0003198 "1657232" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026648", "RXAUI: 7251209", "TUI: T116, T129, T121" ; rdfs:label "Fluarix Quadrivalent 2015-2016" ; rdfs:subClassOf obo:VO_0000983, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003453 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003470 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ] . obo:VO_0003694 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657235" ; obo:VO_0003198 "1657235" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033913", "RXAUI: 7251212", "TUI: T200" ; rdfs:label "Fluarix Quadrivalent 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0003693 . obo:VO_0003695 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657233" ; obo:VO_0003198 "1657233" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033752", "RXAUI: 7251210", "TUI: T200" ; rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2015-2016]" ; rdfs:subClassOf obo:VO_0003693, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003469 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003472 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ] . obo:VO_0003696 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657234" ; obo:VO_0003198 "1657234" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033850", "RXAUI: 7251211", "TUI: T200" ; rdfs:label "FLUARIX QUADRIVALENT 2015-2016 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003694 . obo:VO_0003697 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657236" ; obo:VO_0003198 "1657236" ; obo:VO_0003560 "0.5 ML influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026362", "RXAUI: 7707241, 7251213", "TUI: T200" ; rdfs:label "FLUARIX QUADRIVALENT 2015-2016 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003696, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003695 ] . obo:VO_0003698 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799119" ; obo:VO_0003198 "1799119" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224221", "RXAUI: 8233865", "TUI: T116, T129, T121" ; rdfs:label "Fluarix Quadrivalent 2016-2017" ; rdfs:subClassOf obo:VO_0000983, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003453 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003699 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799122" ; obo:VO_0003198 "1799122" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271754", "RXAUI: 8233868", "TUI: T200" ; rdfs:label "Fluarix Quadrivalent 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003698 . obo:VO_0003700 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799120" ; obo:VO_0003198 "1799120" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271658", "RXAUI: 8233866", "TUI: T200" ; rdfs:label "influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2016-2017]" ; rdfs:subClassOf obo:VO_0003698, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003469 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ] . obo:VO_0003701 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799121" ; obo:VO_0003198 "1799121" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271699", "RXAUI: 8233867", "TUI: T200" ; rdfs:label "FLUARIX QUADRIVALENT 2016-2017 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003699 . obo:VO_0003702 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799123" ; obo:VO_0003198 "1799123" ; obo:VO_0003560 "0.5 ML influenza A virus A/Christchurch/16/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224206", "RXAUI: 8233903, 8233902, 8233869", "TUI: T200" ; rdfs:label "FLUARIX QUADRIVALENT 2016-2017 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003701, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003700 ] . obo:VO_0003703 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928303" ; obo:VO_0003198 "1928303" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490400", "RXAUI: 9198769", "TUI: T116, T129, T121" ; rdfs:label "Fluarix Quadrivalent 2017-2018" ; rdfs:subClassOf obo:VO_0000983, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003704 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928306" ; obo:VO_0003198 "1928306" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490403", "RXAUI: 9198772", "TUI: T200" ; rdfs:label "Fluarix Quadrivalent 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003703 . obo:VO_0003705 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928304" ; obo:VO_0003198 "1928304" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490401", "RXAUI: 9198770", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2017-2018]" ; rdfs:subClassOf obo:VO_0003703, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003706 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928305" ; obo:VO_0003198 "1928305" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490402", "RXAUI: 9198771", "TUI: T200" ; rdfs:label "Fluarix Quadrivalent 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003704 . obo:VO_0003707 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928307" ; obo:VO_0003198 "1928307" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325064", "RXAUI: 9198814, 9198808, 9198773", "TUI: T200" ; rdfs:label "Fluarix Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003706, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003705 ] . obo:VO_0003708 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048962" ; obo:VO_0003198 "2048962" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704189", "RXAUI: 10279939", "TUI: T116, T129, T121" ; rdfs:label "Fluarix Quadrivalent 2018-2019" ; rdfs:subClassOf obo:VO_0000983, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003602 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003709 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048965" ; obo:VO_0003198 "2048965" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704192", "RXAUI: 10279942", "TUI: T200" ; rdfs:label "Fluarix Quadrivalent 2018-2019 Injectable Product" ; rdfs:subClassOf obo:VO_0003708 . obo:VO_0003710 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048963" ; obo:VO_0003198 "2048963" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704190", "RXAUI: 10279940", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Fluarix Quadrivalent 2018-2019]" ; rdfs:subClassOf obo:VO_0003708, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003663 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003664 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003711 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048964" ; obo:VO_0003198 "2048964" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluarix Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704191", "RXAUI: 10279941", "TUI: T200" ; rdfs:label "FLUARIX QUADRIVALENT 2018-2019 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003709 . obo:VO_0003712 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048966" ; obo:VO_0003198 "2048966" ; obo:VO_0003560 "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Fluarix Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704193", "RXAUI: 10279943, 10279945, 10279944", "TUI: T200" ; rdfs:label "FLUARIX QUADRIVALENT 2018-2019 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003711 . obo:VO_0003713 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928290" ; obo:VO_0003198 "1928290" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4490395", "RXAUI: 9198756", "TUI: T116, T129, T121" ; rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen" ; rdfs:subClassOf obo:VO_0015084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003703 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003708 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003727 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003733 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003745 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003751 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003767 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003773 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003791 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003912 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003913 ] . obo:VO_0003714 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928300" ; obo:VO_0003198 "1928300" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4490397", "RXAUI: 9198766", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003713 . obo:VO_0003715 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661803" ; obo:VO_0003198 "1661803" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4020099", "RXAUI: 7264715", "TUI: T129, T121" ; rdfs:label "Afluria 2015-2016" ; rdfs:subClassOf obo:VO_0000006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003475 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ] . obo:VO_0003716 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661806" ; obo:VO_0003198 "1661806" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4047061", "RXAUI: 7264718", "TUI: T200" ; rdfs:label "Afluria 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0003715 . obo:VO_0003717 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661804" ; obo:VO_0003198 "1661804" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4046916", "RXAUI: 7264716", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria 2015-2016]" ; rdfs:subClassOf obo:VO_0003715, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003476 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ] . obo:VO_0003718 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661812" ; obo:VO_0003198 "1661812" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Afluria 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4018775", "RXAUI: 7264729, 7707306, 7264733", "TUI: T200" ; rdfs:label "afluria 2015-2016 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003716, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003717 ] . obo:VO_0003719 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661805" ; obo:VO_0003198 "1661805" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4046988", "RXAUI: 7264717", "TUI: T200" ; rdfs:label "Afluria 2015-2016 Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003716 . obo:VO_0003720 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1661807" ; obo:VO_0003198 "1661807" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4018774", "RXAUI: 7264719, 7264723, 7707305", "TUI: T200" ; rdfs:label "Afluria 2015-2016 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003719, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003717 ] . obo:VO_0003721 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799399" ; obo:VO_0003198 "1799399" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224216", "RXAUI: 8234382", "TUI: T116, T129, T121" ; rdfs:label "Afluria 2016-2017" ; rdfs:subClassOf obo:VO_0000006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003722 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799402" ; obo:VO_0003198 "1799402" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271746", "RXAUI: 8234385", "TUI: T200" ; rdfs:label "Afluria 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003721 . obo:VO_0003723 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799400" ; obo:VO_0003198 "1799400" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271652", "RXAUI: 8234383", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Afluria 2016-2017]" ; rdfs:subClassOf obo:VO_0003721, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ] . obo:VO_0003724 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799413" ; obo:VO_0003198 "1799413" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Injectable Suspension [Afluria 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224196", "RXAUI: 8234404, 8234405, 8234406", "TUI: T200" ; rdfs:label "Afluria 2016-2017 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003722, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003723 ] . obo:VO_0003725 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799401" ; obo:VO_0003198 "1799401" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271691", "RXAUI: 8234384", "TUI: T200" ; rdfs:label "Afluria 2016-2017 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003722 . obo:VO_0003726 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799403" ; obo:VO_0003198 "1799403" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224214", "RXAUI: 8236926, 8234386, 8236927", "TUI: T200" ; rdfs:label "afluria 2016-2017 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003725, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003723 ] . obo:VO_0003727 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942128" ; obo:VO_0003198 "1942128" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325193", "RXAUI: 9267473", "TUI: T129, T121" ; rdfs:label "Afluria 2017-2018" ; rdfs:subClassOf obo:VO_0000006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003728 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942131" ; obo:VO_0003198 "1942131" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4519949", "RXAUI: 9267476", "TUI: T200" ; rdfs:label "Afluria 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003727 . obo:VO_0003729 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942129" ; obo:VO_0003198 "1942129" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4519947", "RXAUI: 9267474", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML [Afluria 2017-2018]" ; rdfs:subClassOf obo:VO_0003727, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003730 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942158" ; obo:VO_0003198 "1942158" ; obo:VO_0003560 "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML Injectable Suspension [Afluria 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325058", "RXAUI: 9267492, 9267490, 9267491", "TUI: T200" ; rdfs:label "Afluria 2017-2018 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003728 . obo:VO_0003731 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942130" ; obo:VO_0003198 "1942130" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4519948", "RXAUI: 1942130", "TUI: T200" ; rdfs:label "Afluria 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003728 . obo:VO_0003732 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942132" ; obo:VO_0003198 "1942132" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325060", "RXAUI: 9267481, 9267480, 9267477", "TUI: T200" ; rdfs:label "Afluria 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003731 . obo:VO_0003733 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050767" ; obo:VO_0003198 "2050767" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719173", "RXAUI: 10290502", "TUI: T116, T129, T121" ; rdfs:label "Afluria 2018-2019" ; rdfs:subClassOf obo:VO_0000006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003602 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003734 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050770" ; obo:VO_0003198 "2050770" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719176", "RXAUI: 10290505", "TUI: T200" ; rdfs:label "Afluria 2018-2019 Injectable Product" ; rdfs:subClassOf obo:VO_0003733 . obo:VO_0003735 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050768" ; obo:VO_0003198 "2050768" ; obo:VO_0003560 "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML [Afluria 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719174", "RXAUI: 10290503", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML [Afluria 2018-2019]" ; rdfs:subClassOf obo:VO_0003733, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003663 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003664 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003736 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050771" ; obo:VO_0003198 "2050771" ; obo:VO_0003560 "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Injectable Suspension [Afluria 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719177", "RXAUI: 10290510, 10290509, 10290506", "TUI: T200" ; rdfs:label "afluria 2018-2019 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003734, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003735 ] . obo:VO_0003737 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050802" ; obo:VO_0003198 "2050802" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719203", "RXAUI: 10290573", "TUI: T200" ; rdfs:label "Afluria 2018-2019 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003734 . obo:VO_0003738 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050803" ; obo:VO_0003198 "2050803" ; obo:VO_0003560 "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe [Afluria 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719204", "RXAUI: 10292876, 10290577, 10292877", "TUI: T200" ; rdfs:label "Afluria 2018-2019 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003737, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003735 ] . obo:VO_0003739 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1858962" ; obo:VO_0003198 "1858962" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4293490", "RXAUI: 8698886", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2016-2017 Formula Injectable Product" ; rdfs:subClassOf obo:VO_0003744 . obo:VO_0003740 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1858960" ; obo:VO_0003198 "1858960" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4293406", "RXAUI: 8698884", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria Quadrivalent 2016-2017 Formula]" ; rdfs:subClassOf obo:VO_0003744, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ] . obo:VO_0003741 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1858966" ; obo:VO_0003198 "1858966" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Afluria Quadrivalent 2016-2017 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4293383", "RXAUI: 8698910, 8698890, 8698911", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2016-2017 Formula Influenza Virus Vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003739, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003740 ] . obo:VO_0003742 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1858961" ; obo:VO_0003198 "1858961" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria Quadrivalent 2016-2017 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4293449", "RXAUI: 8698885", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2016-2017 Formula Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003739 . obo:VO_0003743 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1858963" ; obo:VO_0003198 "1858963" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2016-2017 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4283663", "RXAUI: 8698892, 8698891, 8698887", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2016-2017 Formula 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003742, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003740 ] . obo:VO_0003744 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1858959" ; obo:VO_0003198 "1858959" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4293360", "RXAUI: 8698883", "TUI: T116, T129, T121" ; rdfs:label "Afluria Quadrivalent 2016-2017 Formula" ; rdfs:subClassOf obo:VO_0001817, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003745 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942162" ; obo:VO_0003198 "1942162" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325196", "RXAUI: 9267495", "TUI: T129, T121" ; rdfs:label "Afluria Quadrivalent 2017-2018" ; rdfs:subClassOf obo:VO_0001817, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003746 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942165" ; obo:VO_0003198 "1942165" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4519959", "RXAUI: 9267498", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003745 . obo:VO_0003747 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942163" ; obo:VO_0003198 "1942163" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4519957", "RXAUI: 9267496", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria Quadrivalent 2017-2018]" ; rdfs:subClassOf obo:VO_0003745, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003748 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942173" ; obo:VO_0003198 "1942173" ; obo:VO_0003560 "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Afluria Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325066", "RXAUI: 9267520, 9267517, 9267516", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2017-2018 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003746, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003747 ] . obo:VO_0003749 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942164" ; obo:VO_0003198 "1942164" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4519958", "RXAUI: 9267497", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003746 . obo:VO_0003750 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1942166" ; obo:VO_0003198 "1942166" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/46/2015 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325063", "RXAUI: 9272502, 9267499, 9272501", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003747 ] . obo:VO_0003751 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050791" ; obo:VO_0003198 "2050791" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719195", "RXAUI: 10290555", "TUI: T116, T129, T121" ; rdfs:label "Afluria Quadrivalent 2018-2019" ; rdfs:subClassOf obo:VO_0001817, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003602 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003752 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050794" ; obo:VO_0003198 "2050794" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719198", "RXAUI: 10290558", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2018-2019 Injectable Product" ; rdfs:subClassOf obo:VO_0003751 . obo:VO_0003753 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050792" ; obo:VO_0003198 "2050792" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719196", "RXAUI: 10290556", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Afluria Quadrivalent 2018-2019]" ; rdfs:subClassOf obo:VO_0003751, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003663 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003664 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003754 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050795" ; obo:VO_0003198 "2050795" ; obo:VO_0003560 "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Afluria Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4553815", "RXAUI: 10322944, 10290561, 10290559", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2018-2019 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003752, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003753 ] . obo:VO_0003755 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050796" ; obo:VO_0003198 "2050796" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Afluria Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719199", "RXAUI: 10290562", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2018-2019 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003752 . obo:VO_0003756 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050797" ; obo:VO_0003198 "2050797" ; obo:VO_0003560 "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Afluria Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4553814", "RXAUI: 10322943, 10322942, 10290563", "TUI: T200" ; rdfs:label "Afluria Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003755, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003753 ] . obo:VO_0003757 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799102" ; obo:VO_0003198 "1799102" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224220", "RXAUI: 8233849", "TUI: T116, T129, T121" ; rdfs:label "Flulaval Quadrivalent 2016-2017" ; rdfs:subClassOf obo:VO_0003071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003758 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799105" ; obo:VO_0003198 "1799105" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271755", "RXAUI: 8233852", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003757 . obo:VO_0003759 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799103" ; obo:VO_0003198 "1799103" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271659", "RXAUI: 8233850", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2016-2017]" ; rdfs:subClassOf obo:VO_0003757, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ] . obo:VO_0003760 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799205" ; obo:VO_0003198 "1799205" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Flulaval Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224211", "RXAUI: 1799205", "TUI: T200" ; rdfs:label "FLULAVAL QUADRIVALENT 2016-2017 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003758, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003759 ] . obo:VO_0003761 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799104" ; obo:VO_0003198 "1799104" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flulaval Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271700", "RXAUI: 8233851", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2016-2017 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003758 . obo:VO_0003762 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799106" ; obo:VO_0003198 "1799106" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4255281", "RXAUI: 8233853, 8233905, 8233906", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2016-2017 vaccine 0.5 Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003761, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003759 ] . obo:VO_0003763 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657335" ; obo:VO_0003198 "1657335" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026650", "RXAUI: 7251229", "TUI: T116, T129, T121" ; rdfs:label "FluLaval Quadrivalent 2015-2016" ; rdfs:subClassOf obo:VO_0003071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003470 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ] . obo:VO_0003764 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657338" ; obo:VO_0003198 "1657338" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033911", "RXAUI: 7251232", "TUI: T200" ; rdfs:label "FluLaval Quadrivalent 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0003763 . obo:VO_0003765 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657336" ; obo:VO_0003198 "1657336" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [FluLaval Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033750", "RXAUI: 7251230", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [FluLaval Quadrivalent 2015-2016]" ; rdfs:subClassOf obo:VO_0003763, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003472 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ] . obo:VO_0003766 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657339" ; obo:VO_0003198 "1657339" ; obo:VO_0003560 "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [FluLaval Quadrivalent 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4018811", "RXAUI: 7251233, 7707287", "TUI: T200" ; rdfs:label "FLULAVAL QUADRIVALENT 2015-2016 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003764, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003765 ] . obo:VO_0003767 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928325" ; obo:VO_0003198 "1928325" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325209", "RXAUI: 9198793", "TUI: T116, T129, T121" ; rdfs:label "Flulaval Quadrivalent 2017-2018" ; rdfs:subClassOf obo:VO_0003071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003768 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928328" ; obo:VO_0003198 "1928328" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490418", "RXAUI: 9198796", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003767 . obo:VO_0003769 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928326" ; obo:VO_0003198 "1928326" ; obo:VO_0003560 "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490416", "RXAUI: 9198794", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2017-2018]" ; rdfs:subClassOf obo:VO_0003767, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003770 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928329" ; obo:VO_0003198 "1928329" ; obo:VO_0003560 "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Flulaval Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4319520", "RXAUI: 9198867, 9198866, 9198797", "TUI: T200" ; rdfs:label "FLULAVAL QUADRIVALENT 2017-2018 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003768, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003769 ] . obo:VO_0003771 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928335" ; obo:VO_0003198 "1928335" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flulaval Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490423", "RXAUI: 9198815", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003768 . obo:VO_0003772 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928336" ; obo:VO_0003198 "1928336" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4319519", "RXAUI: 9198862, 9198816, 9198863", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003771, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003769 ] . obo:VO_0003773 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048970" ; obo:VO_0003198 "2048970" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704197", "RXAUI: 10279949", "TUI: T116, T129, T121" ; rdfs:label "Flulaval Quadrivalent 2018-2019" ; rdfs:subClassOf obo:VO_0003071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003602 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003774 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048973" ; obo:VO_0003198 "2048973" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704200", "RXAUI: 10279952", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2018-2019 Injectable Product" ; rdfs:subClassOf obo:VO_0003773 . obo:VO_0003775 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048971" ; obo:VO_0003198 "2048971" ; obo:VO_0003560 "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704198", "RXAUI: 10279950", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML [Flulaval Quadrivalent 2018-2019]" ; rdfs:subClassOf obo:VO_0003773, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003489 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003663 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003664 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003776 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:VO_0003198 "2048974" ; obo:VO_0003560 "http://purl.bioontology.org/ontology/RXNORM/2048974", "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Injectable Suspension [Flulaval Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4552692", "RXAUI: 10279953, 10279956, 10279954", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2018-2019 vaccine Injectable Suspension" ; rdfs:subClassOf obo:VO_0003774, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003775 ] . obo:VO_0003777 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048975" ; obo:VO_0003198 "2048975" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flulaval Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4704201", "RXAUI: 10279957", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2018-2019 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003774 . obo:VO_0003778 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2048976" ; obo:VO_0003198 "2048976" ; obo:VO_0003560 "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.03 MG/ML Prefilled Syringe [Flulaval Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4552691", "RXAUI: 10279960, 10279959, 10279958", "TUI: T200" ; rdfs:label "Flulaval Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003777, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003775 ] . obo:VO_0003779 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657140" ; obo:VO_0003198 "1657140" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026649", "RXAUI: 7251081", "TUI: T116, T129, T121" ; rdfs:label "Flucelvax 2015-2016" ; rdfs:subClassOf obo:VO_0000980, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003475 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003477 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003486 ] . obo:VO_0003780 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657143" ; obo:VO_0003198 "1657143" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033914", "RXAUI: 7251084", "TUI: T200" ; rdfs:label "Flucelvax 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0003779 . obo:VO_0003781 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657141" ; obo:VO_0003198 "1657141" ; obo:VO_0003560 "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033757", "RXAUI: 7251082", "TUI: T200" ; rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax 2015-2016]" ; rdfs:subClassOf obo:VO_0003779, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003476 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003478 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003487 ] . obo:VO_0003782 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657142" ; obo:VO_0003198 "1657142" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033857", "RXAUI: 7251083", "TUI: T200" ; rdfs:label "FLUCELVAX 2015-2016 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003780 . obo:VO_0003783 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657144" ; obo:VO_0003198 "1657144" ; obo:VO_0003560 "0.5 ML influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/South Australia/55/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026363", "RXAUI: 7251085, 8725354, 7707232", "TUI: T200" ; rdfs:label "FLUCELVAX 2015-2016 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003782, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003781 ] . obo:VO_0003784 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801607" ; obo:VO_0003198 "1801607" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4276115", "RXAUI: 8238453", "TUI: T129, T121" ; rdfs:label "Flucelvax Quadrivalent 2016-2017" ; rdfs:subClassOf obo:VO_0003070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003477 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003486 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003789 ] . obo:VO_0003785 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801610" ; obo:VO_0003198 "1801610" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4276265", "RXAUI: 8238456", "TUI: T200" ; rdfs:label "Flucelvax Quadrivalent 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003784 . obo:VO_0003786 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801608" ; obo:VO_0003198 "1801608" ; obo:VO_0003560 "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4276184", "RXAUI: 8238454", "TUI: T200" ; rdfs:label "influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2016-2017]" ; rdfs:subClassOf obo:VO_0003784, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003478 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003487 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003790 ] . obo:VO_0003787 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801609" ; obo:VO_0003198 "1801609" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4276248", "RXAUI: 8238455", "TUI: T200" ; rdfs:label "FLUCELVAX QUADRIVALENT 2016-2017 Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003785 . obo:VO_0003788 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:VO_0003198 "1801611" ; obo:VO_0003560 "0.5 ML influenza A virus A/Brisbane/10/2010 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4256265", "RXAUI: 8238461, 8238460, 8238457", "TUI: T200" ; rdfs:label "FLUCELVAX QUADRIVALENT 2016-2017 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003787, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003786 ] . obo:VO_0003789 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801603" ; obo:VO_0003198 "1801603" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4276030", "RXAUI: 8238449", "TUI: T116, T129, T121" ; rdfs:label "influenza B virus B/Hong Kong/259/2010 antigen" ; rdfs:subClassOf obo:VO_0015086, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003784 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003791 ] . obo:VO_0003790 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801604" ; obo:VO_0003198 "1801604" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4276333", "RXAUI: 8238450", "TUI: T200" ; rdfs:label "influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML" ; rdfs:subClassOf obo:VO_0003789 . obo:VO_0003791 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928533" ; obo:VO_0003198 "1928533" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325207", "RXAUI: 9199341", "TUI: T116, T129, T121" ; rdfs:label "Flucelvax Quadrivalent 2017-2018" ; rdfs:subClassOf obo:VO_0003070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003486 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003789 ] . obo:VO_0003792 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928536" ; obo:VO_0003198 "1928536" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490504", "RXAUI: 9199344", "TUI: T200" ; rdfs:label "Flucelvax Quadrivalent 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003791 . obo:VO_0003793 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928534" ; obo:VO_0003198 "1928534" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490502", "RXAUI: 9199342", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML [Flucelvax Quadrivalent 2017-2018]" ; rdfs:subClassOf obo:VO_0003791, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003487 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003663 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003790 ] . obo:VO_0003794 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928537" ; obo:VO_0003198 "1928537" ; obo:VO_0003560 "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Injectable Suspension [Flucelvax Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490505", "RXAUI: 9199345, 9199362, 9199359", "TUI: T200" ; rdfs:label "FLUCELVAX Quadrivalent 2017-2018 Injectable Suspension" ; rdfs:subClassOf obo:VO_0003792, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003793 ] . obo:VO_0003795 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928539" ; obo:VO_0003198 "1928539" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flucelvax Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490507", "RXAUI: 9199347", "TUI: T200" ; rdfs:label "Flucelvax Quadrivalent 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003792 . obo:VO_0003796 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928540" ; obo:VO_0003198 "1928540" ; obo:VO_0003560 "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Hong Kong/259/2010 antigen 0.03 MG/ML / influenza B virus B/Utah/9/2014 antigen 0.03 MG/ML Prefilled Syringe [Flucelvax Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325069", "RXAUI: 9199352, 9199361, 9199348", "TUI: T200" ; rdfs:label "Flucelvax Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003795, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003793 ] . obo:VO_0003797 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1986826" ; obo:VO_0003198 "1986826" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4530100", "RXAUI: 9698281", "TUI: T129, T121" ; rdfs:label "Shingrix Injectable Product" ; rdfs:subClassOf obo:VO_0003317 . obo:VO_0003798 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1986827" ; obo:VO_0003198 "1986827" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4530101", "RXAUI: 9698282", "TUI: T200" ; rdfs:label "Varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML [Shingrix]" ; rdfs:subClassOf obo:VO_0003317, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003803 ] . obo:VO_0003799 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "0.5 ML Shingrix 0.1 MG/ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1986830" ; obo:VO_0003198 "1986830" ; obo:VO_0003560 "0.5 ML Varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML Injection [Shingrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "RXAUI: 9698706, 9698285, 9698287, 9698286", "TUI: T200" ; rdfs:label "Shingrix vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003797, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003798 ] . obo:VO_0003800 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Shingrix 0.1 MG/ML Injection" ; rdfs:subClassOf obo:VO_0003799 . obo:VO_0003801 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1986821" ; obo:VO_0003198 "1986821" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "CUI: C0061673", "RXAUI: 9698276", "TUI: T116, T129, T121" ; rdfs:label "Varicella zoster virus glycoprotein E" ; rdfs:subClassOf obo:VO_0010792 . obo:VO_0003802 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1986820" ; obo:VO_0003198 "1986820" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "CUI: C4530095", "RXAUI: 9698275", "TUI: T116, T129, T121" ; rdfs:label "Varicella zoster virus glycoprotein E, recombinant" ; rdfs:subClassOf obo:VO_0003801, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:VO_0003317 ] . obo:VO_0003803 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1986822" ; obo:VO_0003198 "1986822" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "CUI: C4530096", "RXAUI: 9698277", "TUI: T200" ; rdfs:label "Varicella zoster virus glycoprotein E, recombinant 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0003802 . obo:VO_0003804 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1664639" ; obo:VO_0003198 "1664639" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4026651", "RXAUI: 7266972", "TUI: T116, T129, T121" ; rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen" ; rdfs:subClassOf obo:VO_0015084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003806 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003807 ] . obo:VO_0003805 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1664467" ; obo:VO_0003198 "1664467" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4050818", "RXAUI: 7266777", "TUI: T200" ; rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML" ; rdfs:subClassOf obo:VO_0003804 . obo:VO_0003806 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1664639" ; obo:VO_0003198 "1664639" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026651", "RXAUI: 7266972", "TUI: T116, T129, T121" ; rdfs:label "Flumist 2015-2016" ; rdfs:subClassOf obo:VO_0000044, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003470 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003804 ] . obo:VO_0003807 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801825" ; obo:VO_0003198 "1801825" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4276113", "RXAUI: 8238995", "TUI: T116, T129, T121" ; rdfs:label "Flumist Quadrivalent 2016-2017" ; rdfs:subClassOf obo:VO_0000982, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003804 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003811 ] . obo:VO_0003808 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1946970" ; obo:VO_0003198 "1946970" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4529647", "RXAUI: 9278624", "TUI: T116, T129, T121" ; rdfs:label "Flumist Quadrivalent 2017-2018" ; rdfs:subClassOf obo:VO_0000982, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003811 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003818 ] . obo:VO_0003809 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1664644" ; obo:VO_0003198 "1664644" ; obo:VO_0003560 "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML Nasal Spray [Flumist 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4026361", "RXAUI: 7266797, 7266977, 7266796", "TUI: T200" ; rdfs:label "FluMist Quadrivalent, 2015-2016 Formula Nasal Spray" ; rdfs:subClassOf obo:VO_0003806, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003810 ] . obo:VO_0003810 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1664640" ; obo:VO_0003198 "1664640" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4050879", "RXAUI: 7266973", "TUI: T200" ; rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML [Flumist 2015-2016]" ; rdfs:subClassOf obo:VO_0000044, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003474 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003481 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003493 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003805 ] . obo:VO_0003811 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801767" ; obo:VO_0003198 "1801767" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4276025", "RXAUI: 8238906", "TUI: T116, T129, T121" ; rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen" ; rdfs:subClassOf obo:VO_0015085, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003807 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003808 ] . obo:VO_0003812 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801822" ; obo:VO_0003198 "1801822" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4276331", "RXAUI: 8238992", "TUI: T200" ; rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML" ; rdfs:subClassOf obo:VO_0003811 . obo:VO_0003813 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801826" ; obo:VO_0003198 "1801826" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4276182", "RXAUI: 8238996", "TUI: T200" ; rdfs:label "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML [Flumist Quadrivalent 2016-2017]" ; rdfs:subClassOf obo:VO_0000982, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003481 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003493 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003805 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003812 ] . obo:VO_0003814 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "FluMist Quadrivalent, Live Attenuated, 2016-2017 Formula Nasal Spray" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801830" ; obo:VO_0003198 "1801830" ; obo:VO_0003560 "influenza A virus A/Bolivia/559/2013 (H1N1) antigen 50000000 MG/ML / influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 50000000 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 50000000 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 50000000 MG/ML Nasal Spray [Flumist Quadrivalent 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224207", "RXAUI: 8239001, 8239002, 8239000", "TUI: T200" ; rdfs:label "FluMist Quadrivalent, 2016-2017 Formula Nasal Spray" ; rdfs:subClassOf obo:VO_0003807, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003813 ] . obo:VO_0003815 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1946985" ; obo:VO_0003198 "1946985" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4529659", "RXAUI: 9278648", "TUI: T200" ; rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML [Flumist Quadrivalent 2017-2018]" ; rdfs:subClassOf obo:VO_0003808, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003485 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003492 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003817 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003819 ] . obo:VO_0003816 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "FluMist Quadrivalent, Live Attenuated, 2017-2018 Formula Nasal Spray" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1946986" ; obo:VO_0003198 "1946986" ; obo:VO_0003560 "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Brisbane/60/2008 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray [Flumist Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4522486", "RXAUI: 9278652, 9278649, 9278653", "TUI: T200" ; rdfs:label "FluMist Quadrivalent, 2017-2018 Formula Nasal Spray" ; rdfs:subClassOf obo:VO_0003808, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003815 ] . obo:VO_0003817 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1946980" ; obo:VO_0003198 "1946980" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4529654", "RXAUI: 9278643", "TUI: T200" ; rdfs:label "influenza A virus A/New Caledonia/71/2014 (H3N2) antigen 158000000 UNT/ML" ; rdfs:subClassOf obo:VO_0003811 . obo:VO_0003818 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1946964" ; obo:VO_0003198 "1946964" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4522494", "RXAUI: 9278618", "TUI: T116, T129, T121" ; rdfs:label "influenza A virus A/Slovenia/2903/2015 (H1N1) antigen" ; rdfs:subClassOf obo:VO_0015084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003808 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003820 ] . obo:VO_0003819 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1946981" ; obo:VO_0003198 "1946981" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4529655", "RXAUI: 9278644", "TUI: T200" ; rdfs:label "influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML" ; rdfs:subClassOf obo:VO_0003818 . obo:VO_0003820 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2054182" ; obo:VO_0003198 "2054182" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719703", "RXAUI: 10329701", "TUI: T116, T129, T121" ; rdfs:label "Flumist Quadrivalent 2018-2019" ; rdfs:subClassOf obo:VO_0000982, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003818 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003821 ] . obo:VO_0003821 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2054177" ; obo:VO_0003198 "2054177" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4719701", "RXAUI: 10329696", "TUI: T116, T129, T121" ; rdfs:label "influenza B virus B/Colorado/06/2017 antigen" ; rdfs:subClassOf obo:VO_0015086, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003820 ] . obo:VO_0003822 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2054271" ; obo:VO_0003198 "2054271" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4719748", "RXAUI: 10329902", "TUI: T200" ; rdfs:label "influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML" ; rdfs:subClassOf obo:VO_0003821 . obo:VO_0003823 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2054273" ; obo:VO_0003198 "2054273" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719750", "RXAUI: 10329904", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML [Flumist Quadrivalent 2018-2019]" ; rdfs:subClassOf obo:VO_0003820, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003492 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003819 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003822 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003825 ] . obo:VO_0003824 obo:IAO_0000118 "FluMist Quadrivalent, Live Attenuated, 2018-2019 Formula Nasal Spray" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2054274" ; obo:VO_0003198 "2054274" ; obo:VO_0003560 "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 158000000 UNT/ML / influenza A virus A/Slovenia/2903/2015 (H1N1) antigen 158000000 UNT/ML / influenza B virus B/Colorado/06/2017 antigen 158000000 UNT/ML / influenza B virus B/Phuket/3073/2013 antigen 158000000 UNT/ML Nasal Spray [Flumist Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719751", "RXAUI: 10329907, 10329905, 10329906", "TUI: T200" ; rdfs:label "FluMist Quadrivalent, 2018-2019 Formula Nasal Spray" ; rdfs:subClassOf obo:VO_0003820, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003823 ] . obo:VO_0003825 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2054270" ; obo:VO_0003198 "2054270" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4719747", "RXAUI: 10329901", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 158000000 UNT/ML" ; rdfs:subClassOf obo:VO_0003601 . obo:VO_0003826 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1166526" ; obo:VO_0003198 "1166526" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3220746", "RXAUI: 3837627", "TUI: T200" ; rdfs:label "Havrix Injectable Product" ; rdfs:subClassOf obo:VO_0000052 . obo:VO_0003827 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798365" ; obo:VO_0003198 "798365" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344345", "RXAUI: 2851478", "TUI: T200" ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML [Havrix]" ; rdfs:subClassOf obo:VO_0003826, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003431 ] . obo:VO_0003828 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "0.5 ML Havrix 1440 UNT/ML Injection", "Havrix 720 UNT per 0.5 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658066" ; obo:VO_0003198 "1658066" ; obo:VO_0003560 "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injection [Havrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3888157", "RXAUI: 7252248, 7252247, 7253517, 7252251", "TUI: T200" ; rdfs:label "HAVRIX pediatric/adolescent vaccine 720 UNT in 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003830, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003827 ] . obo:VO_0003829 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "1 ML Havrix 1440 UNT/ML Injection", "Havrix 1440 UNT per 1 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658060" ; obo:VO_0003198 "1658060" ; obo:VO_0003560 "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Injection [Havrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1637805", "RXAUI: 7252240, 7253646, 7252252, 7252239", "TUI: T200" ; rdfs:label "HAVRIX adult vaccine 1440 UNT in 1 ML Injection" ; rdfs:subClassOf obo:VO_0003830, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003827 ] . obo:VO_0003830 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658059" ; obo:VO_0003198 "1658059" ; obo:VO_0003560 "Hepatitis A Vaccine (Inactivated) Strain HM175 Injection [Havrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033811", "RXAUI: 7252238", "TUI: T200" ; rdfs:label "HAVRIX Injection" ; rdfs:subClassOf obo:VO_0003826 . obo:VO_0003831 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "HAVRIX pediatric/adolescent vaccine 720 UNT in 0.5 ML Prefilled Syringe", "Havrix 720 UNT per 0.5 ML Prefilled Syringe, 0.5 ML" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798482" ; obo:VO_0003198 "798482" ; obo:VO_0003560 "0.5 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344406", "RXAUI: 3271879, 7253645, 3066070, 2851611", "TUI: T200" ; rdfs:label "Havrix, Hepatitis A Vaccine (Inactivated), (Pediatric Dose) 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003833, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003827 ] . obo:VO_0003832 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 1440 UNT/ML Prefilled Syringe [Havrix]", "HAVRIX adult vaccine 1440 UNT in 1 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798479" ; obo:VO_0003198 "798479" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1322283", "RXAUI: 2851606, 7239762, 7253516", "TUI: T200" ; rdfs:label "Havrix, Hepatitis A Vaccine (Inactivated), (Adult Dose) 1 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003833, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003827 ] . obo:VO_0003833 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798478" ; obo:VO_0003198 "798478" ; obo:VO_0003560 "Hepatitis A Vaccine (Inactivated) Strain HM175 Prefilled Syringe [Havrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344405", "RXAUI: 2851605", "TUI: T200" ; rdfs:label "Havrix Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003826 . obo:VO_0003834 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "poliovirus vaccine inactivated" ; rdfs:subClassOf obo:VO_0000664 . obo:VO_0003835 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/763096" ; obo:VO_0003198 "763096" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2242156", "RXAUI: 5026693", "TUI: T129, T121" ; rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney)" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003834, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000054 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000082 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000084 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003836 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/763098" ; obo:VO_0003198 "763098" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2242158", "RXAUI: 5026694", "TUI: T129, T121" ; rdfs:label "poliovirus vaccine inactivated, type 2 (MEF-1)" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003834, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000054 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000082 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000084 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003837 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/763100" ; obo:VO_0003198 "763100" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2242160", "RXAUI: 5026695", "TUI: T129, T121" ; rdfs:label "poliovirus vaccine inactivated, type 3 (Saukett)" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003834, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000054 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000067 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000082 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000084 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010736 ] . obo:VO_0003838 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1178815" ; obo:VO_0003198 "1178815" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3232713", "RXAUI: 3842767", "TUI: T200" ; rdfs:label "PEDIARIX Injectable Product" ; rdfs:subClassOf obo:VO_0000082 . obo:VO_0003839 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/829972" ; obo:VO_0003198 "829972" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586685", "RXAUI: 5027365", "TUI: T200" ; rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [PEDIARIX]" ; rdfs:subClassOf obo:VO_0003838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003256 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003391 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003401 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003456 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003843 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003844 ] . obo:VO_0003840 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/829988" ; obo:VO_0003198 "829988" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Hepatitis B Surface Antigen Vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe [PEDIARIX]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586690", "RXAUI: 5027414", "TUI: T200" ; rdfs:label "PEDIARIX vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003838 . obo:VO_0003841 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/829989" ; obo:VO_0003198 "829989" ; obo:VO_0003560 "0.5 ML acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe [PEDIARIX]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586691", "RXAUI: 3634543, 7253748, 5027677", "TUI: T200" ; rdfs:label "PEDIARIX vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003840, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003839 ] . obo:VO_0003842 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/763097" ; obo:VO_0003198 "763097" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2242157", "RXAUI: 5027171", "TUI: T200" ; rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML" ; rdfs:subClassOf obo:VO_0003835 . obo:VO_0003843 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/763099" ; obo:VO_0003198 "763099" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2242159", "RXAUI: 5027167", "TUI: T200" ; rdfs:label "poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML" ; rdfs:subClassOf obo:VO_0003836 . obo:VO_0003844 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/763101" ; obo:VO_0003198 "763101" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2242161", "RXAUI: 5027168", "TUI: T200" ; rdfs:label "poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML" ; rdfs:subClassOf obo:VO_0003837 . obo:VO_0003845 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300806" ; obo:VO_0003198 "1300806" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2719943", "RXAUI: 4626294", "TUI: T116, T129, T121" ; rdfs:label "Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine" ; rdfs:subClassOf obo:VO_0015014 . obo:VO_0003846 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1176753" ; obo:VO_0003198 "1176753" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3230691", "RXAUI: 3838525", "TUI: T200" ; rdfs:label "Ipol Injectable Product" ; rdfs:subClassOf obo:VO_0000054 . obo:VO_0003847 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/763104" ; obo:VO_0003198 "763104" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2242163", "RXAUI: 5027360", "TUI: T200" ; rdfs:label "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML [Ipol]" ; rdfs:subClassOf obo:VO_0000054, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003843 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003844 ] . obo:VO_0003848 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/763106" ; obo:VO_0003198 "763106" ; obo:VO_0003560 "poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML Injectable Solution [Ipol]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1877934", "RXAUI: 5027670, 6816444, 7253746", "TUI: T200" ; rdfs:label "IPOL vaccine Injectable Solution" ; rdfs:subClassOf obo:VO_0003846, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003847 ] . obo:VO_0003849 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/807219" ; obo:VO_0003198 "807219" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0078221", "RXAUI: 2863812", "TUI: T116, T129, T121" ; rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003443, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000104 ] . obo:VO_0003850 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1187511" ; obo:VO_0003198 "1187511" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3241253", "RXAUI: 3848865", "TUI: T200" ; rdfs:label "Typhim VI Injectable Product" ; rdfs:subClassOf obo:VO_0000104 . obo:VO_0003851 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/807223" ; obo:VO_0003198 "807223" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2365227", "RXAUI: 2863816", "TUI: T200" ; rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML [Typhim VI]" ; rdfs:subClassOf obo:VO_0000104, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003855 ] . obo:VO_0003852 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/807225" ; obo:VO_0003198 "807225" ; obo:VO_0003560 "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Injectable Solution [Typhim VI]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0711001", "RXAUI: 7251850, 2863819, 2863818", "TUI: T200" ; rdfs:label "Typhim Vi Injectable Solution" ; rdfs:subClassOf obo:VO_0003850, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003851 ] . obo:VO_0003853 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1486495" ; obo:VO_0003198 "1486495" ; obo:VO_0003560 "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain Prefilled Syringe [Typhim VI]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3701103", "RXAUI: 5937066", "TUI: T200" ; rdfs:label "Typhim VI Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003850 . obo:VO_0003854 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "0.5 ML Typhim VI 0.05 MG/ML Prefilled Syringe", "Typhim VI 25 MCG per 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1486496" ; obo:VO_0003198 "1486496" ; obo:VO_0003560 "0.5 ML Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML Prefilled Syringe [Typhim VI]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0980908", "RXAUI: 7252822, 5937069, 5937068, 5937067", "TUI: T200" ; rdfs:label "Typhim Vi 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003853, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003851 ] . obo:VO_0003855 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/807220" ; obo:VO_0003198 "807220" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2365225", "RXAUI: 2863813", "TUI: T200" ; rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.05 MG/ML" ; rdfs:subClassOf obo:VO_0003849 . obo:VO_0003856 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1361664" ; obo:VO_0003198 "1361664" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3528060", "RXAUI: 5037103", "TUI: T200" ; rdfs:label "Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain 0.025 MG/ML" ; rdfs:subClassOf obo:VO_0003849 . obo:VO_0003857 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830464" ; obo:VO_0003198 "830464" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586803", "RXAUI: 5026921", "TUI: T129, T121" ; rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000063 ] . obo:VO_0003858 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830465" ; obo:VO_0003198 "830465" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586804", "RXAUI: 5027213", "TUI: T200" ; rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML" ; rdfs:subClassOf obo:VO_0003857 . obo:VO_0003859 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659733" ; obo:VO_0003198 "1659733" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4047087", "RXAUI: 7255368", "TUI: T200" ; rdfs:label "Imovax Injectable Product" ; rdfs:subClassOf obo:VO_0000063 . obo:VO_0003860 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1659731" ; obo:VO_0003198 "1659731" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4046958", "RXAUI: 7255366", "TUI: T200" ; rdfs:label "rabies virus vaccine wistar strain PM-1503-3M (Human), Inactivated 2.5 UNT/ML [Imovax]" ; rdfs:subClassOf obo:VO_0000063 . obo:VO_0003861 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "IMOVAX rabies vaccine 2.5 UNT in 1 ML Injection", "Imovax Rabies, Wistar Rabies Virus Strain PM-1503-3M (Human) 2.5 UNT per 1 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830470" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0711018", "RXAUI: 7253451, 7250938, 7255369, 7255370", "TUI: T200" ; rdfs:label "1 ML Imovax 2.5 UNT/ML Injection" ; rdfs:subClassOf obo:VO_0003859 . obo:VO_0003862 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830457" ; obo:VO_0003198 "830457" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586798", "RXAUI: 2939884", "TUI: T129, T121" ; rdfs:label "rabies virus vaccine flury-lep strain" ; rdfs:subClassOf obo:VO_0000650 . obo:VO_0003863 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830458" ; obo:VO_0003198 "830458" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586799", "RXAUI: 2939885", "TUI: T200" ; rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML" ; rdfs:subClassOf obo:VO_0003862 . obo:VO_0003864 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1177669" ; obo:VO_0003198 "1177669" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3231586", "RXAUI: 3844818", "TUI: T200" ; rdfs:label "RabAvert Injectable Product" ; rdfs:subClassOf obo:VO_0000094 . obo:VO_0003865 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830461" ; obo:VO_0003198 "830461" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586802", "RXAUI: 2939888", "TUI: T200" ; rdfs:label "rabies virus vaccine flury-lep strain 2.5 UNT/ML [RabAvert]" ; rdfs:subClassOf obo:VO_0000094, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003863 ] . obo:VO_0003866 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "RabAvert 2.5 UNT in 1 ML Injection", "RabAvert 2.5 UNT per 1 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830463" ; obo:VO_0003198 "830463" ; obo:VO_0003560 "1 ML rabies virus vaccine flury-lep strain 2.5 UNT/ML Injection [RabAvert]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0711019", "RXAUI: 7253136, 7250934, 7252193, 7252192", "TUI: T200" ; rdfs:label "1 ML RabAvert 2.5 UNT/ML Injection" ; rdfs:subClassOf obo:VO_0003864, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003865 ] . obo:VO_0003867 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1169861" ; obo:VO_0003198 "1169861" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3223997", "RXAUI: 3837729", "TUI: T200" ; rdfs:label "Hiberix Injectable Product" ; rdfs:subClassOf obo:VO_0010715 . obo:VO_0003868 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300809" ; obo:VO_0003198 "1300809" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2719732", "RXAUI: 4626297", "TUI: T200" ; rdfs:label "Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML [Hiberix]" ; rdfs:subClassOf obo:VO_0010715, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003870 ] . obo:VO_0003869 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "0.5 ML Hiberix 0.07 MG/ML Injection", "Hiberix (Haemophilus influenzae type b strain 20,752, capsular polysaccharide (10 MCG) inactivated tetanus toxoid (25 MCG) conjugate vaccine) per 0.5 ML Injection", "Hiberix (Haemophilus influenzae type b strain 20,752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine) 35 MCG per 0.5 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300810" ; obo:VO_0003198 "1300810" ; obo:VO_0003560 "0.5 ML Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML Injection [Hiberix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2719734", "RXAUI: 7252256, 7252207, 7253591, 7252257, 7252206", "TUI: T200" ; rdfs:label "HIBERIX vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003867, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003868 ] . obo:VO_0003870 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300807" ; obo:VO_0003198 "1300807" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2719728", "RXAUI: 4626295", "TUI: T200" ; rdfs:label "Haemophilus influenzae type b strain 20752, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.07 MG/ML" ; rdfs:subClassOf obo:VO_0003845 . obo:VO_0003871 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1170172" ; obo:VO_0003198 "1170172" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3224301", "RXAUI: 3831445", "TUI: T200" ; rdfs:label "COMVAX Injectable Product" ; rdfs:subClassOf obo:VO_0000028 . obo:VO_0003872 obo:IAO_0000118 "Comvax (Haemophilus influenzae b (Ross strain) capsular polysaccharide (7.5 MCG) Meningococcal Protein (125 MCG) Conjugate Vaccine / Hepatitis B Surface Antigen Vaccine 5 MCG) per 0.5 ML Injection", "Comvax, Haemophilus b Conjugate (Meningococcal Protein Conjugate) and Hepatitis B (Recombinant) Vaccine Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798443" ; obo:VO_0003198 "798443" ; obo:VO_0003560 """Preferred Name 0.5 ML Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML / Hepatitis B Surface Antigen Vaccine 0.01 MG/ML Injection [COMVAX]""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0714228", "RXAUI: 7251580, 7251337, 7253592, 7251338", "TUI: T200" ; rdfs:label "COMVAX Injection 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003871 . obo:VO_0003873 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798441" ; obo:VO_0003198 "798441" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344381", "RXAUI: 3020182", "TUI: T200" ; rdfs:label "Haemophilus influenzae b (Ross strain) capsular polysaccharide Meningococcal Protein Conjugate Vaccine 0.265 MG/ML / Hepatitis B Surface Antigen Vaccine 0.01 MG/ML [COMVAX]" ; rdfs:subClassOf obo:VO_0000028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003413 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003423 ] . obo:VO_0003874 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1367001" ; obo:VO_0003198 "1367001" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3531472", "RXAUI: 5048926", "TUI: T116, T121" ; rdfs:label "Flublok 2012-2013 Formula" ; rdfs:subClassOf obo:VO_0000978, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003497 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003507 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003521 ] . obo:VO_0003875 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1367004" ; obo:VO_0003198 "1367004" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3531475", "RXAUI: 5048929", "TUI: T200" ; rdfs:label "Flublok 2012-2013 Formula Injectable Product" ; rdfs:subClassOf obo:VO_0003874 . obo:VO_0003876 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:VO_0003198 "1367005" ; obo:VO_0003560 "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML Injectable Solution [Flublok 2012-2013 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3531476", "RXAUI: 5048931, 5048930", "TUI: T200" ; rdfs:label "Flublok 2012-2013 Formula Influenza Virus Vaccine Injectable Solution" ; rdfs:subClassOf obo:VO_0003875, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003877 ] . obo:VO_0003877 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1367002" ; obo:VO_0003198 "1367002" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3531473", "RXAUI: 5048927", "TUI: T200" ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Wisconsin-1-2010-like virus 0.09 MG/ML [Flublok 2012-2013 Formula]" ; rdfs:subClassOf obo:VO_0003874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003509 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003513 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003522 ] . obo:VO_0003878 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1442206" ; obo:VO_0003198 "1442206" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3692550", "RXAUI: 5532833", "TUI: T116, T121" ; rdfs:label "Flublok 2013-2014 Formula" ; rdfs:subClassOf obo:VO_0000978, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003497 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003507 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003526 ] . obo:VO_0003879 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1442209" ; obo:VO_0003198 "1442209" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3692553", "RXAUI: 5532836", "TUI: T200" ; rdfs:label "Flublok 2013-2014 Formula Injectable Product" ; rdfs:subClassOf obo:VO_0003878 . obo:VO_0003880 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1442210" ; obo:VO_0003198 "1442210" ; obo:VO_0003560 "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Injectable Solution [Flublok 2013-2014 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3651109", "RXAUI: 5532837, 5532838", "TUI: T200" ; rdfs:label "Flublok 2013-2014 Formula Influenza Virus Vaccine Injectable Solution" ; rdfs:subClassOf obo:VO_0003879, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003881 ] . obo:VO_0003881 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1442207" ; obo:VO_0003198 "1442207" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3692551", "RXAUI: 5532834", "TUI: T200" ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML [Flublok 2013-2014 Formula]" ; rdfs:subClassOf obo:VO_0003878, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003509 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003513 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003528 ] . obo:VO_0003882 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1537517" ; obo:VO_0003198 "1537517" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3817315", "RXAUI: 6338485", "TUI: T116, T121" ; rdfs:label "Flublok 2014-2015 Formula" ; rdfs:subClassOf obo:VO_0000978, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003497 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003507 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003526 ] . obo:VO_0003883 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1537520" ; obo:VO_0003198 "1537520" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3819829", "RXAUI: 6338488", "TUI: T200" ; rdfs:label "Flublok 2014-2015 Formula Injectable Product" ; rdfs:subClassOf obo:VO_0003882 . obo:VO_0003884 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1537521" ; obo:VO_0003198 "1537521" ; obo:VO_0003560 "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML Injectable Solution [Flublok 2014-2015 Formula]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3817268", "RXAUI: 6338489, 6338490", "TUI: T200" ; rdfs:label "Flublok 2014-2015 Formula Influenza Virus Vaccine Injectable Solution" ; rdfs:subClassOf obo:VO_0003883, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003885 ] . obo:VO_0003885 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1537518" ; obo:VO_0003198 "1537518" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3819293", "RXAUI: 6338486", "TUI: T200" ; rdfs:label "Influenza A virus vaccine, A-California-7-2009 (H1N1)-like virus 0.09 MG/ML / Influenza A virus vaccine, A-Victoria-361-2011 (H3N2)-like virus 0.09 MG/ML / Influenza B virus vaccine, B-Massachusetts-2-2012-like virus 0.09 MG/ML [Flublok 2014-2015 Formula]" ; rdfs:subClassOf obo:VO_0003882, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003509 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003513 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003528 ] . obo:VO_0003886 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1660925" ; obo:VO_0003198 "1660925" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4020135", "RXAUI: 7258098", "TUI: T129, T121" ; rdfs:label "Flublok 2015-2016" ; rdfs:subClassOf obo:VO_0000978, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003470 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ] . obo:VO_0003887 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1660928" ; obo:VO_0003198 "1660928" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4047076", "RXAUI: 7258101", "TUI: T200" ; rdfs:label "Flublok 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0003886 . obo:VO_0003888 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1660926" ; obo:VO_0003198 "1660926" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4046941", "RXAUI: 7258099", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok 2015-2016]" ; rdfs:subClassOf obo:VO_0003886, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003450 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003490 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003658 ] . obo:VO_0003889 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1660929" ; obo:VO_0003198 "1660929" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Injection [Flublok 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4019692", "RXAUI: 7258105, 7258102", "TUI: T200" ; rdfs:label "Flublok 2015-2016 vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003888 ] . obo:VO_0003890 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1803020" ; obo:VO_0003560 "1803020" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224215", "RXAUI: 8241253", "TUI: T116, T129, T121" ; rdfs:label "Flublok 2016-2017" ; rdfs:subClassOf obo:VO_0000978, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003891 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1803023" ; obo:VO_0003198 "1803023" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4276258", "RXAUI: 8241256", "TUI: T200" ; rdfs:label "Flublok 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003890 . obo:VO_0003892 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1803021" ; obo:VO_0003198 "1803021" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4276177", "RXAUI: 8241254", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML [Flublok 2016-2017]" ; rdfs:subClassOf obo:VO_0003890, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003450 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003482 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003660 ] . obo:VO_0003893 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1803024" ; obo:VO_0003198 "1803024" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML Injection [Flublok 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4224212", "RXAUI: 8241260, 8241257, 8241263", "TUI: T200" ; rdfs:label "Flublok 2016-2017 vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003891, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003892 ] . obo:VO_0003894 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928876" ; obo:VO_0003198 "1928876" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490679", "RXAUI: 9199818", "TUI: T116, T129, T121" ; rdfs:label "Flublok 2017-2018" ; rdfs:subClassOf obo:VO_0000978, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003600 ] . obo:VO_0003895 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928879" ; obo:VO_0003198 "1928879" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490682", "RXAUI: 9199821", "TUI: T200" ; rdfs:label "Flublok 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003894 . obo:VO_0003896 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928877" ; obo:VO_0003198 "1928877" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490680", "RXAUI: 9199819", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML [Flublok 2017-2018]" ; rdfs:subClassOf obo:VO_0003894, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003482 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003660 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003662 ] . obo:VO_0003897 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928880" ; obo:VO_0003198 "1928880" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML Injection [Flublok 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490683", "RXAUI: 9199203, 9199204, 9199822", "TUI: T200" ; rdfs:label "Flublok 2017-2018 vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003895, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003896 ] . obo:VO_0003898 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928347" ; obo:VO_0003198 "1928347" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490433", "RXAUI: 9198836", "TUI: T116, T129, T121" ; rdfs:label "Flublok Quadrivalent 2017-2018" ; rdfs:subClassOf obo:VO_0003067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003600 ] . obo:VO_0003899 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928350" ; obo:VO_0003198 "1928350" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490435", "RXAUI: 9198839", "TUI: T200" ; rdfs:label "Flublok Quadrivalent 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003898 . obo:VO_0003900 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928361" ; obo:VO_0003198 "1928361" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490441", "RXAUI: 9198889", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok Quadrivalent 2017-2018]" ; rdfs:subClassOf obo:VO_0003898, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003482 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003490 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003660 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003662 ] . obo:VO_0003901 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928362" ; obo:VO_0003198 "1928362" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.09 MG/ML / influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490442", "RXAUI: 9198860, 9198861, 9198890", "TUI: T200" ; rdfs:label "Flublok Quadrivalent 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003902, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003900 ] . obo:VO_0003902 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928349" ; obo:VO_0003198 "1928349" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flublok Quadrivalent 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490434", "RXAUI: 9198838", "TUI: T200" ; rdfs:label "Flublok Quadrivalent 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003899 . obo:VO_0003903 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050378" ; obo:VO_0003198 "2050378" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719023", "RXAUI: 10289675", "TUI: T200" ; rdfs:label "Flublok Quadrivalent 2018-2019" ; rdfs:subClassOf obo:VO_0003067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003600 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003602 ] . obo:VO_0003904 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050381" ; obo:VO_0003198 "2050381" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719026", "RXAUI: 10289678", "TUI: T200" ; rdfs:label "Flublok Quadrivalent 2018-2019 Injectable Product" ; rdfs:subClassOf obo:VO_0003903 . obo:VO_0003905 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050379" ; obo:VO_0003198 "2050379" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719024", "RXAUI: 10289676", "TUI: T200" ; rdfs:label "influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML [Flublok Quadrivalent 2018-2019]" ; rdfs:subClassOf obo:VO_0003903, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003490 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003662 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003908 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003909 ] . obo:VO_0003906 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050380" ; obo:VO_0003198 "2050380" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Flublok Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719025", "RXAUI: 10289677", "TUI: T200" ; rdfs:label "Flublok Quadrivalent 2018-2019 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003904 . obo:VO_0003907 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050382" ; obo:VO_0003198 "2050382" ; obo:VO_0003560 "0.5 ML influenza A virus A/Michigan/45/2015 (H1N1) antigen 0.09 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML / influenza B virus B/Phuket/3073/2013 antigen 0.09 MG/ML Prefilled Syringe [Flublok Quadrivalent 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719027", "RXAUI: 10289680, 10289679, 10289681", "TUI: T200" ; rdfs:label "Flublok Quadrivalent 2018-2019 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003906, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003905 ] . obo:VO_0003908 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050374" ; obo:VO_0003198 "2050374" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4719019", "RXAUI: 10289671", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003601 . obo:VO_0003909 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050375" ; obo:VO_0003198 "2050375" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4719020", "RXAUI: 10289672", "TUI: T200" ; rdfs:label "influenza B virus B/Maryland/15/2016 antigen 0.09 MG/ML" ; rdfs:subClassOf obo:VO_0003602 . obo:VO_0003910 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1724002" ; obo:VO_0003198 "1724002" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4060062", "RXAUI: 7710863", "TUI: T116, T121" ; rdfs:label "FLUAD 2015-2016" ; rdfs:subClassOf obo:VO_0004281, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003470 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003914 ] . obo:VO_0003911 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801078" ; obo:VO_0003198 "1801078" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271566", "RXAUI: 8236918", "TUI: T116, T129, T121" ; rdfs:label "Fluad 2016-2017" ; rdfs:subClassOf obo:VO_0004281, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ] . obo:VO_0003912 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928961" ; obo:VO_0003198 "1928961" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325205", "RXAUI: 9199981", "TUI: T116, T129, T121" ; rdfs:label "Fluad 2017-2018" ; rdfs:subClassOf obo:VO_0004281, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003599 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003913 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050759" ; obo:VO_0003198 "2050759" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719165", "RXAUI: 10290487", "TUI: T116, T129, T121" ; rdfs:label "Fluad 2018-2019" ; rdfs:subClassOf obo:VO_0004281, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003601 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003602 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003713 ] . obo:VO_0003914 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1723997" ; obo:VO_0003198 "1723997" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4059934", "RXAUI: 7710856", "TUI: T116, T129, T121" ; rdfs:label "influenza B virus B/Brisbane/9/2014 antigen" ; rdfs:subClassOf obo:VO_0015086, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003910 ] . obo:VO_0003915 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1724000" ; obo:VO_0003198 "1724000" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4060367", "RXAUI: 7710861", "TUI: T200" ; rdfs:label "influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML" ; rdfs:subClassOf obo:VO_0003914 . obo:VO_0003916 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1724005" ; obo:VO_0003198 "1724005" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4060278", "RXAUI: 7710866", "TUI: T200" ; rdfs:label "FLUAD 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0003910 . obo:VO_0003917 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1724011" ; obo:VO_0003198 "1724011" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4060159", "RXAUI: 7710874", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML [FLUAD 2015-2016]" ; rdfs:subClassOf obo:VO_0003910, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003452 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003473 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003915 ] . obo:VO_0003918 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1724004" ; obo:VO_0003198 "1724004" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [FLUAD 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4060234", "RXAUI: 7710865", "TUI: T200" ; rdfs:label "FLUAD 2015-2016 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003916 . obo:VO_0003919 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "FLUAD 2015-2016 Formula Influenza Virus Vaccine 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1724012" ; obo:VO_0003198 "1724012" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.015 MG/ML / influenza A virus A/Switzerland/9715293/2013 (H3N2) antigen 0.015 MG/ML / influenza B virus B/Brisbane/9/2014 antigen 0.015 MG/ML Prefilled Syringe [FLUAD 2015-2016]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4059806", "RXAUI: 7710870, 7710875, 7716409", "TUI: T200" ; rdfs:label "FLUAD 2015-2016 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003917 ] . obo:VO_0003920 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801081" ; obo:VO_0003198 "1801081" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271737", "RXAUI: 8236921", "TUI: T200" ; rdfs:label "Fluad 2016-2017 Injectable Product" ; rdfs:subClassOf obo:VO_0003911 . obo:VO_0003921 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801079" ; obo:VO_0003198 "1801079" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "C4271636", "RXAUI: 8236919", "TUI: T200" ; rdfs:label "influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluad 2016-2017]" ; rdfs:subClassOf obo:VO_0003911, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ] . obo:VO_0003922 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801080" ; obo:VO_0003198 "1801080" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271677", "RXAUI: 8236920", "TUI: T200" ; rdfs:label "Fluad 2016-2017 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003920 . obo:VO_0003923 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1801082" ; obo:VO_0003198 "1801082" ; obo:VO_0003560 "0.5 ML influenza A virus A/California/7/2009 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2016-2017]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4270828", "RXAUI: 8236922, 8236925, 8236924", "TUI: T200" ; rdfs:label "Fluad 2016-2017 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003922, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003921 ] . obo:VO_0003924 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928964" ; obo:VO_0003198 "1928964" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490740", "RXAUI: 9199984", "TUI: T200" ; rdfs:label "Fluad 2017-2018 Injectable Product" ; rdfs:subClassOf obo:VO_0003912 . obo:VO_0003925 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928962" ; obo:VO_0003198 "1928962" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490738", "RXAUI: 9199982", "TUI: T200" ; rdfs:label "influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML [Fluad 2017-2018]" ; rdfs:subClassOf obo:VO_0003912, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003480 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003659 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003926 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928963" ; obo:VO_0003198 "1928963" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4490739", "RXAUI: 9199983", "TUI: T200" ; rdfs:label "Fluad 2017-2018 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003924 . obo:VO_0003927 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1928965" ; obo:VO_0003198 "1928965" ; obo:VO_0003560 "0.5 ML influenza A virus A/Hong Kong/4801/2014 (H3N2) antigen 0.03 MG/ML / influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza B virus B/Brisbane/60/2008 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2017-2018]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4325070", "RXAUI: 9199987, 9199985, 9199986", "TUI: T200" ; rdfs:label "Fluad 2017-2018 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003926, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003925 ] . obo:VO_0003928 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050762" ; obo:VO_0003198 "2050762" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719168", "RXAUI: 10290491", "TUI: T200" ; rdfs:label "Fluad 2018-2019 Injectable Product" ; rdfs:subClassOf obo:VO_0003913 . obo:VO_0003929 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050760" ; obo:VO_0003198 "2050760" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719166", "RXAUI: 10290488", "TUI: T200" ; rdfs:label "influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML [Fluad 2018-2019]" ; rdfs:subClassOf obo:VO_0003913, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003663 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003664 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003714 ] . obo:VO_0003930 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050761" ; obo:VO_0003198 "2050761" ; obo:VO_0003560 "influenza A virus (H1N1) antigen / influenza A virus (H3N2) antigen / influenza B virus antigen Prefilled Syringe [Fluad 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719167", "RXAUI: 10290490", "TUI: T200" ; rdfs:label "Fluad 2018-2019 vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003928 . obo:VO_0003931 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050763" ; obo:VO_0003198 "2050763" ; obo:VO_0003560 "0.5 ML influenza A virus A/Singapore/GP1908/2015 (H1N1) antigen 0.03 MG/ML / influenza A virus A/Singapore/INFIMH-16-0019/2016 (H3N2) antigen 0.03 MG/ML / influenza B virus B/Maryland/15/2016 antigen 0.03 MG/ML Prefilled Syringe [Fluad 2018-2019]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4719169", "RXAUI: 10290492, 10290493, 10290494", "TUI: T200" ; rdfs:label "Fluad 2018-2019 vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003929 ] . obo:VO_0003932 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1176026" ; obo:VO_0003198 "1176026" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3229980", "RXAUI: 3836903", "TUI: T200" ; rdfs:label "Gardasil Injectable Product" ; rdfs:subClassOf obo:VO_0000049 . obo:VO_0003933 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798272" ; obo:VO_0003198 "798272" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344300", "RXAUI: 2851350", "TUI: T200" ; rdfs:label "L1 protein, Human papillomavirus type 11 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 16 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 6 Vaccine 0.04 MG/ML [Gardasil]" ; rdfs:subClassOf obo:VO_0000049, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003938 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003939 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015032 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015040 ] . obo:VO_0003934 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1656961" ; obo:VO_0003198 "1656961" ; obo:VO_0003560 "L1 protein, Human papillomavirus type 11 Vaccine / L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine / L1 protein, Human papillomavirus type 6 Vaccine Injection [Gardasil]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344301", "RXAUI: 7250795", "TUI: T200" ; rdfs:label "GARDASIL Injection" ; rdfs:subClassOf obo:VO_0003932 . obo:VO_0003935 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798274" ; obo:VO_0003198 "798274" ; obo:VO_0003560 "0.5 ML L1 protein, Human papillomavirus type 11 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 16 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 6 Vaccine 0.04 MG/ML Injection [Gardasil]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1714255", "RXAUI: 7250530, 6836567, 7251909", "TUI: T200" ; rdfs:label "GARDASIL 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003934, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003933 ] . obo:VO_0003936 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798277" ; obo:VO_0003198 "798277" ; obo:VO_0003560 "L1 protein, Human papillomavirus type 11 Vaccine / L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine / L1 protein, Human papillomavirus type 6 Vaccine Prefilled Syringe [Gardasil]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344303", "RXAUI: 2851356", "TUI: T200" ; rdfs:label "GARDASIL Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003932 . obo:VO_0003937 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798278" ; obo:VO_0003198 "798278" ; obo:VO_0003560 "0.5 ML L1 protein, Human papillomavirus type 11 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 16 Vaccine 0.08 MG/ML / L1 protein, Human papillomavirus type 18 Vaccine 0.04 MG/ML / L1 protein, Human papillomavirus type 6 Vaccine 0.04 MG/ML Prefilled Syringe [Gardasil]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1725928", "RXAUI: 2851357, 2980898, 6836565", "TUI: T200" ; rdfs:label "GARDASIL 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003936, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003933 ] . obo:VO_0003938 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798265" ; obo:VO_0003198 "798265" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344294", "RXAUI: 2851343", "TUI: T200" ; rdfs:label "L1 protein, Human papillomavirus type 16 Vaccine 0.08 MG/ML" ; rdfs:subClassOf obo:VO_0003303 . obo:VO_0003939 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798269" ; obo:VO_0003198 "798269" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344298", "RXAUI: 2851347", "TUI: T200" ; rdfs:label "L1 protein, Human papillomavirus type 6 Vaccine 0.04 MG/ML" ; rdfs:subClassOf obo:VO_0003300 . obo:VO_0003940 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1301885" ; obo:VO_0003198 "1301885" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2724165", "RXAUI: 4627784", "TUI: T116, T121" ; rdfs:label "Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine" ; rdfs:subClassOf obo:VO_0003303, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0011559 ] . obo:VO_0003941 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1301887" ; obo:VO_0003198 "1301887" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2724167", "RXAUI: 4627786", "TUI: T116, T129, T121" ; rdfs:label "Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine" ; rdfs:subClassOf obo:VO_0003302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0011559 ] . obo:VO_0003942 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1301886" ; obo:VO_0003198 "1301886" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2725255", "RXAUI: 4627785", "TUI: T200" ; rdfs:label "Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML" ; rdfs:subClassOf obo:VO_0003940 . obo:VO_0003943 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1301888" ; obo:VO_0003198 "1301888" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3474821", "RXAUI: 4627787", "TUI: T200" ; rdfs:label "Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML" ; rdfs:subClassOf obo:VO_0003941 . obo:VO_0003944 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1167355" ; obo:VO_0003198 "1167355" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3221549", "RXAUI: 3832040", "TUI: T200" ; rdfs:label "Cervarix Injectable Product" ; rdfs:subClassOf obo:VO_0011559 . obo:VO_0003945 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1301890" ; obo:VO_0003198 "1301890" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2725256", "RXAUI: 4627789", "TUI: T200" ; rdfs:label "Human papillomavirus type 16, L1 capsid protein (residues 2-471) vaccine 0.04 MG/ML / Human papillomavirus type 18, L1 capsid protein (residues 2-472) vaccine 0.04 MG/ML [Cervarix]" ; rdfs:subClassOf obo:VO_0011559, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003942 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003943 ] . obo:VO_0003946 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/867488" ; obo:VO_0003198 "867488" ; obo:VO_0003560 "L1 protein, Human papillomavirus type 16 Vaccine / L1 protein, Human papillomavirus type 18 Vaccine Prefilled Syringe [Cervarix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2723809", "RXAUI: 2999023", "TUI: T200" ; rdfs:label "CERVARIX Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003944 . obo:VO_0003947 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Cervarix Human Papillomavirus bivalent (types 16 and 18) vaccine, recombinant 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1301891" ; obo:VO_0003198 "1301891" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2724157", "RXAUI: 3266660, 4627790, 7236130", "TUI: T200" ; rdfs:label "CERVARIX 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003946, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003945 ] . obo:VO_0003948 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/845525" ; obo:VO_0003198 "845525" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1579318", "RXAUI: 2963098", "TUI: T129, T121" ; rdfs:label "Japanese encephalitis virus vaccine, inactivated" ; rdfs:subClassOf obo:VO_0000665 . obo:VO_0003949 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300779" ; obo:VO_0003198 "1300779" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3474322", "RXAUI: 4626258", "TUI: T129, T121" ; rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0011558 ] . obo:VO_0003950 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300780" ; obo:VO_0003198 "1300780" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2682867", "RXAUI: 4626259", "TUI: T200" ; rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML" ; rdfs:subClassOf obo:VO_0003949 . obo:VO_0003951 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1167200" ; obo:VO_0003198 "1167200" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3221394", "RXAUI: 3838660", "TUI: T200" ; rdfs:label "Ixiaro Injectable Product" ; rdfs:subClassOf obo:VO_0011558 . obo:VO_0003952 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300782" ; obo:VO_0003198 "1300782" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2682871", "RXAUI: 4626261", "TUI: T200" ; rdfs:label "Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML [Ixiaro]" ; rdfs:subClassOf obo:VO_0011558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003950 ] . obo:VO_0003953 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/845531" ; obo:VO_0003198 "845531" ; obo:VO_0003560 "Japanese encephalitis virus vaccine, inactivated Prefilled Syringe [Ixiaro]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2682872", "RXAUI: 2963104", "TUI: T200" ; rdfs:label "Ixiaro (Japanese Encephalitis Vaccine, Inactivated, Adsorbed) Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003951 . obo:VO_0003954 obo:IAO_0000118 "Ixiaro (Japanese Encephalitis Vaccine, Inactivated, Adsorbed) 0.012 MG/ML 0.5 ML Prefilled Syringe", "Ixiaro 6 MCG per 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300783" ; obo:VO_0003198 "1300783" ; obo:VO_0003560 "0.5 ML Japanese encephalitis virus vaccine Nakayama-NIH strain, inactivated 0.012 MG/ML Prefilled Syringe [Ixiaro]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2682873", "RXAUI: 6833047, 4626263, 2984288, 4626262, 2994485", "TUI: T200" ; rdfs:label "0.5 ML Ixiaro 0.012 MG/ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003953, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003952 ] . obo:VO_0003955 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1812935" ; obo:VO_0003198 "1812935" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4291328", "RXAUI: 8262960", "TUI: T116, T129, T121" ; rdfs:label "vibrio cholerae CVD 103-HGR strain live antigen" ; rdfs:subClassOf obo:VO_0000919, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0003082 ] . obo:VO_0003956 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1812935" ; obo:VO_0003198 "1812935" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4291328", "RXAUI: 8262960", "TUI: T200" ; rdfs:label "vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML" ; rdfs:subClassOf obo:VO_0003955 . obo:VO_0003957 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1812950" ; obo:VO_0003198 "1812950" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4291505", "RXAUI: 8262971", "TUI: T200" ; rdfs:label "Vaxchora Oral Product" ; rdfs:subClassOf obo:VO_0003082 . obo:VO_0003958 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1172748" ; obo:VO_0003198 "1172748" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3226798", "RXAUI: 3838385", "TUI: T200" ; rdfs:label "Infanrix Injectable Product" ; rdfs:subClassOf obo:VO_0000064 . obo:VO_0003959 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/854946" ; obo:VO_0003198 "854946" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal capsular polysaccharide type 10A vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000088 ] . obo:VO_0003960 oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Neisseria meningitidis vaccine antigen" ; rdfs:subClassOf obo:VO_0000919 . obo:VO_0003961 obo:IAO_0000115 "replication defective simian adenoviral vector expressing KH, a self-cleaving polyprotein comprising L. donovani KMP-11 and HASPB" ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/28498840" ; obo:VO_0001818 "5712" ; obo:VO_0003147 "KH, a self-cleaving polyprotein comprising L. donovani HASPB and KMP-11 Proteins" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ChAd63-KH vaccine" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011157 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0001047 ] . obo:VO_0003962 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1812948" ; obo:VO_0003198 "1812948" ; obo:VO_0003560 "Cholera Vaccine Oral Suspension [Vaxchora]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4291477", "RXAUI: 8262969", "TUI: T200" ; rdfs:label "Vaxchora Oral Suspension" ; rdfs:subClassOf obo:VO_0003957 . obo:VO_0003963 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1812951" ; obo:VO_0003198 "1812951" ; obo:VO_0003560 "vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML Oral Suspension [Vaxchora]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271028", "RXAUI: 8262973, 8262974, 8262972", "TUI: T200" ; rdfs:label "Vaxchora 1,200,000,000 UNT per 100 ML Oral Suspension" ; rdfs:subClassOf obo:VO_0003962, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003964 ] . obo:VO_0003964 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1812947" ; obo:VO_0003198 "1812947" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4291443", "RXAUI: 8262968", "TUI: T200" ; rdfs:label "vibrio cholerae CVD 103-HGR strain live antigen 12000000 UNT/ML [Vaxchora]" ; rdfs:subClassOf obo:VO_0003082, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003956 ] . obo:VO_0003965 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050058" ; obo:VO_0003198 "2050058" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4718905", "RXAUI: 9712930", "TUI: T200" ; rdfs:label "Heplisav-B Injectable Product" ; rdfs:subClassOf obo:VO_0003152 . obo:VO_0003966 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050058" ; obo:VO_0003198 "2050058" ; obo:VO_0003560 "Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Heplisav-B]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4718905", "RXAUI: 10287780", "TUI: T200" ; rdfs:label "HEPLISAV-B Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003965 . obo:VO_0003967 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "0.5 ML Heplisav-B 0.04 MG/ML Prefilled Syringe", "HEPLISAV-B 20 MCG in 0.5 ML Prefilled Syringe", "Heplisav-B 0.04 MG/ML per 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/2050059" ; obo:VO_0003198 "2050059" ; obo:VO_0003560 "0.5 ML Hepatitis B Surface Antigen Vaccine 0.04 MG/ML Prefilled Syringe [Heplisav-B]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4553167", "RXAUI: 10287788, 10287789, 10287781, 10287783, 10287782", "TUI: T200" ; rdfs:label "HEPLISAV-B 20 MCG per 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003966, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003968 ] . obo:VO_0003968 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1994349" ; obo:VO_0003198 "1994349" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4541386", "RXAUI: 9712928", "TUI: T200" ; rdfs:label "Hepatitis B Surface Antigen Vaccine 0.04 MG/ML [Heplisav-B]" ; rdfs:subClassOf obo:VO_0003152, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003230 ] . obo:VO_0003969 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/801829" ; obo:VO_0003198 "801829" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2346335", "RXAUI: 5027208", "TUI: T200" ; rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML" ; rdfs:subClassOf obo:VO_0015014 . obo:VO_0003970 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1184583" ; obo:VO_0003198 "1184583" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3238386", "RXAUI: 3843263", "TUI: T200" ; rdfs:label "Pentacel Injectable Product" ; rdfs:subClassOf obo:VO_0000084 . obo:VO_0003971 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/805376" ; obo:VO_0003198 "805376" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364460", "RXAUI: 5027344", "TUI: T200" ; rdfs:label "acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Pentacel]" ; rdfs:subClassOf obo:VO_0000084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003392 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003395 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003401 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003843 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003844 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003969 ] . obo:VO_0003972 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657397" ; obo:VO_0003198 "1657397" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection [Pentacel]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033845", "RXAUI: 7251281", "TUI: T200" ; rdfs:label "Pentacel vaccine Injection" ; rdfs:subClassOf obo:VO_0003970 . obo:VO_0003973 obo:IAO_0000118 "Pentacel DTaP-IPV/Hib (Diphtheria and Tetanus Toxoids and Acellular Pertussis, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate)) 0.5 ML Injection" ; obo:VO_0003198 "805378" ; obo:VO_0003560 "0.5 ML acellular pertussis vaccine, inactivated 96 UNT/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 68 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Pentacel]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2346346", "RXAUI: 7251683, 7253749, 7250887", "TUI: T200" ; rdfs:label "Pentacel vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003972, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003971 ] . obo:VO_0003974 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1171400" ; obo:VO_0003198 "1171400" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3225481", "RXAUI: 3838975", "TUI: T200" ; rdfs:label "Kinrix Injectable Product" ; rdfs:subClassOf obo:VO_0000067 . obo:VO_0003975 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830550" ; obo:VO_0003198 "830550" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586836", "RXAUI: 5027347", "TUI: T200" ; rdfs:label "acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Kinrix]" ; rdfs:subClassOf obo:VO_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003391 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003401 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003456 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003843 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003844 ] . obo:VO_0003976 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657886" ; obo:VO_0003198 "1657886" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033746", "RXAUI: 7251903", "TUI: T200" ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Kinrix]" ; rdfs:subClassOf obo:VO_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003203 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003207 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003386 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003401 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003456 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003843 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003844 ] . obo:VO_0003977 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830556" ; obo:VO_0003198 "830556" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Prefilled Syringe [Kinrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586841", "RXAUI: 5027411", "TUI: T200" ; rdfs:label "KINRIX vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003974 . obo:VO_0003978 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "KINRIX DTaP-IPV (Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine) 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/830557" ; obo:VO_0003198 "830557" ; obo:VO_0003560 "0.5 ML acellular pertussis vaccine, inactivated 0.116 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe [Kinrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586842", "RXAUI: 7253751, 5027675, 3634544", "TUI: T200" ; rdfs:label "KINRIX vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003977, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003975 ] . obo:VO_0003979 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657887" ; obo:VO_0003198 "1657887" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / poliovirus vaccine inactivated, type 1 (Mahoney) / poliovirus vaccine inactivated, type 2 (MEF-1) / poliovirus vaccine inactivated, type 3 (Saukett) / tetanus toxoid vaccine, inactivated Injection [Kinrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586837", "RXAUI: 7251904", "TUI: T200" ; rdfs:label "KINRIX vaccine Injection" ; rdfs:subClassOf obo:VO_0003974 . obo:VO_0003980 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "KINRIX DTaP-IPV (Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine) 0.5 ML Injection" ; obo:VO_0003198 "830552" ; obo:VO_0003560 "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Kinrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2586838", "RXAUI: 7250882, 7251905, 7253750", "TUI: T200" ; rdfs:label "KINRIX vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003979, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003976 ] . obo:VO_0003981 obo:VO_0003198 "1168164" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3222333", "RXAUI: 3833478", "TUI: T200", "http://purl.bioontology.org/ontology/RXNORM/1168164" ; rdfs:label "Daptacel Injectable Product" ; rdfs:subClassOf obo:VO_0000029 . obo:VO_0003982 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300309" ; obo:VO_0003198 "1300309" ; obo:VO_0003560 "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.02 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Daptacel]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2609933", "RXAUI: 5027355", "TUI: T200" ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.02 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Daptacel]" ; 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oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1169838", "RXAUI: 7251885, 7250857, 7250858, 7253754", "TUI: T200" ; rdfs:label "DAPTACEL vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003981, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003982 ] . obo:VO_0003984 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1169952" ; obo:VO_0003198 "1169952" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3224088", "RXAUI: 3828634", "TUI: T200" ; rdfs:label "Adacel Injectable Product" ; rdfs:subClassOf obo:VO_0000005 . obo:VO_0003985 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300190" ; obo:VO_0003198 "1300190" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2587006", "RXAUI: 5027353", "TUI: T200" ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Adacel]" ; rdfs:subClassOf obo:VO_0000005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003204 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003208 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003352 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003374 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003385 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003429 ] . obo:VO_0003986 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/904262" ; obo:VO_0003198 "904262" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Adacel]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2746860", "RXAUI: 5027415", "TUI: T200" ; rdfs:label "Adacel Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003984 . obo:VO_0003987 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300191" ; obo:VO_0003198 "1300191" ; obo:VO_0003560 "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Adacel]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2746861", "RXAUI: 4625204, 7252705, 5027658, 4625563", "TUI: T200" ; rdfs:label "Adacel 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003986, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003985 ] . obo:VO_0003988 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657767" ; obo:VO_0003198 "1657767" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Adacel]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033829", "RXAUI: 7251690", "TUI: T200" ; rdfs:label "Adacel Injection" ; rdfs:subClassOf obo:VO_0003984 . obo:VO_0003989 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Adacel (Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 5 MCG / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 5 MCG / Bordetella pertussis pertactin vaccine, inactivated 3 MCG / Bordetella pertussis toxoid vaccine, inactivated 2.5 MCG / Diphtheria Toxoid Vaccine 2 UNT / Tetanus Toxoid Vaccine 5 UNT) per 0.5 ML Injection", "Adacel Tdap (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed) Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300206" ; obo:VO_0003198 "1300206" ; obo:VO_0003560 "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.01 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.005 MG/ML / diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Adacel]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1639148", "RXAUI: 7250855, 7251691, 7252702, 7250854", "TUI: T200" ; rdfs:label "Adacel 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003988, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003985 ] . obo:VO_0003990 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300383" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "1300383", "CUI: C3152863", "RXAUI: 5027354", "TUI: T200" ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML [Infanrix]" ; rdfs:subClassOf obo:VO_0000064, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003203 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003207 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003386 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003401 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003456 ] . obo:VO_0003991 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657878" ; obo:VO_0003198 "1657878" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Infanrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2368976", "RXAUI: 7251893", "TUI: T200" ; rdfs:label "INFANRIX vaccine Injection" ; rdfs:subClassOf obo:VO_0003958 . obo:VO_0003992 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Infanrix (Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.025 MG / Bordetella pertussis pertactin vaccine, inactivated 0.008 MG / Bordetella pertussis toxoid vaccine, inactivated 0.025 MG / diphtheria toxoid vaccine, inactivated 25 UNT / tetanus toxoid vaccine, inactivated 10 UNT) per 0.5 ML Injection", "Infanrix DTaP (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed) Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300386" ; obo:VO_0003198 "1300386" ; obo:VO_0003560 "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Injection [Infanrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0710622", "RXAUI: 7250871, 7251894, 7250870, 7253756", "TUI: T200" ; rdfs:label "INFANRIX vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003990 ] . obo:VO_0003993 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/824539" ; obo:VO_0003198 "824539" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Infanrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2368973", "RXAUI: 5027387", "TUI: T200" ; rdfs:label "INFANRIX vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003958 . obo:VO_0003994 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Infanrix (Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 25 MCG / Bordetella pertussis pertactin vaccine, inactivated 8 MCG / Bordetella pertussis toxoid vaccine, inactivated 25 MCG / diphtheria toxoid vaccine, inactivated 25 UNT / tetanus toxoid vaccine, inactivated 10 UNT) per 0.5 ML Prefilled Syringe", "Infanrix DTaP (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed) 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300384" ; obo:VO_0003198 "1300384" ; obo:VO_0003560 "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.05 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.05 MG/ML / diphtheria toxoid vaccine, inactivated 50 UNT/ML / tetanus toxoid vaccine, inactivated 20 UNT/ML Prefilled Syringe [Infanrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2368974", "RXAUI: 5027659, 7253755, 3633959, 4625557", "TUI: T200" ; rdfs:label "INFANRIX vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003993, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003990 ] . obo:VO_0003995 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1175718" ; obo:VO_0003198 "1175718" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3229697", "RXAUI: 3831021", "TUI: T200" ; rdfs:label "Boostrix Injectable Product" ; rdfs:subClassOf obo:VO_0000015 . obo:VO_0003996 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657603" ; obo:VO_0003198 "1657603" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033749", "RXAUI: 7251494", "TUI: T200" ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 UNT/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Boostrix]" ; rdfs:subClassOf obo:VO_0000015, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003205 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003206 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003383 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003385 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003387 ] . obo:VO_0003997 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300369" ; obo:VO_0003198 "1300369" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364904", "RXAUI: 5027356", "TUI: T200" ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Boostrix]" ; rdfs:subClassOf obo:VO_0000015, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003206 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003383 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003385 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003387 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004207 ] . obo:VO_0003998 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Boostrix]", "http://purl.bioontology.org/ontology/RXNORM/1657466" ; obo:VO_0003198 "1657466" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364905", "RXAUI: 7251319", "TUI: T200" ; rdfs:label "BOOSTRIX vaccine Injection" ; rdfs:subClassOf obo:VO_0003995 . obo:VO_0003999 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Boostrix (Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 8 MCG / Bordetella pertussis pertactin vaccine, inactivated 2.5 MCG / Bordetella pertussis toxoid vaccine, inactivated 8 MCG / diphtheria toxoid vaccine, inactivated 2.5 UNT / tetanus toxoid vaccine, inactivated 5 UNT) per 0.5 ML Injection", "Boostrix Tdap (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed) Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300378" ; obo:VO_0003198 "1300378" ; obo:VO_0003560 "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 UNT/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Boostrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364906", "RXAUI: 7250865, 7251497, 7253758, 7250866", "TUI: T200" ; rdfs:label "BOOSTRIX vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0003998, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003996 ] . obo:VO_0004000 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella melitensis bp26 mutant vaccine" ; rdfs:seeAlso "violinID: 3259" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:VO_0002561 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004001 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella melitensis omp25 mutant vaccine" ; rdfs:seeAlso "violinID: 3261" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:VO_0002566 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004002 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella melitensis omp31 mutant vaccine" ; rdfs:seeAlso "violinID: 3262" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0001039 ; owl:someValuesFrom obo:VO_0002567 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004003 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies recombinant vector vaccine encoding gp50 protein" ; rdfs:seeAlso "violinID: 826" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:VO_0001093 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0002736 ] ) ] ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0004004 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BoNT/C" ; rdfs:seeAlso "violinID: 91" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010905 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004005 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae CbpA Protein Vaccine" ; rdfs:seeAlso "violinID: 787" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011203 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004006 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae ClpP protein Vaccine" ; rdfs:seeAlso "violinID: 789" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011193 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004007 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae PspA Protein Vaccine" ; rdfs:seeAlso "violinID: 795" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011204 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004008 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae SrtA Protein Vaccine" ; rdfs:seeAlso "violinID: 798" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011199 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004009 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. caninum NcPDI Protein Vaccine" ; rdfs:seeAlso "violinID: 937" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011191 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] . obo:VO_0004010 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. caninum NcDG1 protein vaccine" ; rdfs:seeAlso "violinID: 944" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011202 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] . obo:VO_0004011 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. meningitidis ExbB Protein Vaccine" ; rdfs:seeAlso "violinID: 947" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011186 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0004012 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. meningitidis LctP Protein Vaccine" ; rdfs:seeAlso "violinID: 948" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011185 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0004013 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. meningitidis NspA Protein Vaccine" ; rdfs:seeAlso "violinID: 956" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011184 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0004014 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. miningitidis TBP2 Protein Vaccine" ; rdfs:seeAlso "violinID: 957" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011182 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0004015 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding HA from Influenza A virus (A/Hong Kong/1/68(H3N2))" ; rdfs:seeAlso "violinID: 998" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011120 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004016 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding HA from Influenza A virus (A/environment/Hong Kong/156/1997(H5N1))" ; rdfs:seeAlso "violinID: 999" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011121 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004017 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus HA protein vaccine (Influenza A virus (A/Yamagata/120/1986(H1N1)))" ; rdfs:seeAlso "violinID: 1003" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011126 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004018 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus HA protein vaccine (Influenza A virus (A/Fukuoka/C29/85(H3N2)))" ; rdfs:seeAlso "violinID: 1004" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011127 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004019 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding HA from Influenza B virus (B/Ibaraki/2/85)" ; rdfs:seeAlso "violinID: 1005" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011129 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004020 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding HA from Influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1))" ; rdfs:seeAlso "violinID: 1012" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011140 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004021 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding HA from Influenza A virus (A/equine/Kentucky/1/1981(H3N8))" ; rdfs:seeAlso "violinID: 1014" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011302 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004022 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani GRP-78 Protein Vaccine" ; rdfs:seeAlso "violinID: 1029" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011152 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004023 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani Beta-tubulin Protein Vaccine" ; rdfs:seeAlso "violinID: 1031" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011155 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004024 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. pallidum GlpQ Protein Vaccine" ; rdfs:seeAlso "violinID: 1069" ; rdfs:subClassOf obo:VO_0001230, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012399 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_160 ] . obo:VO_0004025 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. pallidum TmpB Protein Vaccine" ; rdfs:seeAlso "violinID: 1070" ; rdfs:subClassOf obo:VO_0001230, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012400 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_160 ] . obo:VO_0004026 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. pallidum Tp92 Protein Vaccine" ; rdfs:seeAlso "violinID: 1071" ; rdfs:subClassOf obo:VO_0001230, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012401 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_160 ] . obo:VO_0004027 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. burgdorferi DbpA Protein Vaccine" ; rdfs:seeAlso "violinID: 1072" ; rdfs:subClassOf obo:VO_0000764, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012387 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0004028 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. burgdorferi OspA Protein Vaccine" ; rdfs:seeAlso "violinID: 1074" ; rdfs:subClassOf obo:VO_0000764, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012384 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0004029 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. burgdorferi OspB Protein Vaccine" ; rdfs:seeAlso "violinID: 1075" ; rdfs:subClassOf obo:VO_0000764, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012385 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0004030 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. burgdorferi OspC Protein Vaccine" ; rdfs:seeAlso "violinID: 1076" ; rdfs:subClassOf obo:VO_0000764, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012386 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0004031 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. monocytogenes DNA Vaccine encoding hly" ; rdfs:seeAlso "violinID: 1077" ; rdfs:subClassOf obo:VO_0002500, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012388 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1639 ] . obo:VO_0004032 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. monocytogenes p60 Protein Vaccine" ; rdfs:seeAlso "violinID: 1078" ; rdfs:subClassOf obo:VO_0002500, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012404 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1639 ] . obo:VO_0004033 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani Hsp70 Protein Vaccine" ; rdfs:seeAlso "violinID: 1109" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011156 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004034 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "F. tularensis FopB Protein Vaccine" ; rdfs:seeAlso "violinID: 1111" ; rdfs:subClassOf obo:VO_0000152, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011070 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_263 ] . obo:VO_0004035 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA vaccine ESAT-6" ; rdfs:seeAlso "violinID: 3543" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012368 ] . obo:VO_0004036 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus DNA vaccine EBOV GP" ; rdfs:seeAlso "violinID: 3576" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010858 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004037 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus EBOV NP" ; rdfs:seeAlso "violinID: 3577" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010859 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004038 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Nontypeable H. influenzae NucA Protein vaccine" ; rdfs:seeAlso "violinID: 192" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012405 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_727 ] . obo:VO_0004039 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Psuedorabies DNA vaccine encoding IE180 protein" ; rdfs:seeAlso "violinID: 822" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011242 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0004040 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies Subunit gI Protein Vaccine" ; rdfs:seeAlso "violinID: 829" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011251 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0004041 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies Subunit gB Protein Vaccine" ; rdfs:seeAlso "violinID: 830" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011238 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0004042 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. neurona SAG1 Protein Vaccine" ; rdfs:seeAlso "violinID: 835" ; rdfs:subClassOf obo:VO_0000935, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011253 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_42890 ] . obo:VO_0004043 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rotavirus VP6 Protein Vaccine" ; rdfs:seeAlso "violinID: 877" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011222 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] . obo:VO_0004044 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. major PSA-2 Protein Vaccine" ; rdfs:seeAlso "violinID: 1006" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011279 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004045 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. major H2B Protein Vaccine" ; rdfs:seeAlso "violinID: 1009" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011277 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004046 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. major DNA Vaccine encoding Gp63" ; rdfs:seeAlso "violinID: 1013" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011278 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004047 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. aureus ClfA Protein Vaccine" ; rdfs:seeAlso "violinID: 1082" ; rdfs:subClassOf obo:VO_0002502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012390 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0004048 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. aureus CNA Protein Vaccine" ; rdfs:seeAlso "violinID: 1083" ; rdfs:subClassOf obo:VO_0002502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012389 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0004049 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. aureus FnbA Protein Vaccine" ; rdfs:seeAlso "violinID: 1084" ; rdfs:subClassOf obo:VO_0002502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012392 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0004050 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. agalactiae BPS Protein Vaccine" ; rdfs:seeAlso "violinID: 1086" ; rdfs:subClassOf obo:VO_0001375, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012393 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1311 ] . obo:VO_0004051 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. agalactiae Rib Protein Vaccine" ; rdfs:seeAlso "violinID: 1087" ; rdfs:subClassOf obo:VO_0001375, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012403 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1311 ] . obo:VO_0004052 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. agalactiae Sip Protein Vaccine" ; rdfs:seeAlso "violinID: 1088" ; rdfs:subClassOf obo:VO_0001375, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012402 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1311 ] . obo:VO_0004053 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pyogenes Emm1 Protein Vaccine" ; rdfs:seeAlso "violinID: 1089" ; rdfs:subClassOf obo:VO_0002852, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012397 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] . obo:VO_0004054 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pyogenes FbaA Protein Vaccine" ; rdfs:seeAlso "violinID: 1090" ; rdfs:subClassOf obo:VO_0002852, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012396 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] . obo:VO_0004055 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pyogenes FBP54 Protein Vaccine" ; rdfs:seeAlso "violinID: 1091" ; rdfs:subClassOf obo:VO_0002852, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012395 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] . obo:VO_0004056 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pyogenes SfbI Protein Vaccine" ; rdfs:seeAlso "violinID: 1092" ; rdfs:subClassOf obo:VO_0002852, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] . obo:VO_0004057 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pyogenes Sib35 Protein Vaccine" ; rdfs:seeAlso "violinID: 1093" ; rdfs:subClassOf obo:VO_0002852, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012398 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] . obo:VO_0004058 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA Vaccine encoding KatG" ; rdfs:seeAlso "violinID: 1094" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012369 ] . obo:VO_0004059 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis HBHA Protein Vaccine" ; rdfs:seeAlso "violinID: 1095" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012373 ] . obo:VO_0004060 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori HspA Protein Vaccine" ; rdfs:seeAlso "violinID: 1097" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012377 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0004061 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori HspB Protein Vaccine" ; rdfs:seeAlso "violinID: 1098" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012378 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0004062 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori GltA Protein Vaccine" ; rdfs:seeAlso "violinID: 1099" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012379 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0004063 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae PhpA-79 Protein Vaccine" ; rdfs:seeAlso "violinID: 1100" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012383 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004064 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. meningitidis TbpA Protein Vaccine" ; rdfs:seeAlso "violinID: 1101" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0012380 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0004065 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. berghei MSP1 Protein Vaccine" ; rdfs:seeAlso "violinID: 1105" ; rdfs:subClassOf obo:VO_0002513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011225 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004066 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. infantum SMT Protein Vaccine" ; rdfs:seeAlso "violinID: 1108" ; rdfs:subClassOf obo:VO_0012159, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011282 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5671 ] . obo:VO_0004067 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani HASPB1 Protein Vaccine" ; rdfs:seeAlso "violinID: 1028" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:VO_0011162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004068 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae GtS Protein Vaccine" ; rdfs:seeAlso "violinID: 790" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004069 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae 6PGD Protein Vaccine" ; rdfs:seeAlso "violinID: 792" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004070 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae PiaA Protein Vaccine" ; rdfs:seeAlso "violinID: 793" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004071 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae RASV synthesizing PsaA" ; rdfs:seeAlso "violinID: 794" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004072 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus recombinant adenovirus vector vaccine ADV-GP/NP" ; rdfs:seeAlso "violinID: 61" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004073 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GP and NP" ; rdfs:seeAlso "violinID: 71" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004074 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BoNT/A(Hc)" ; rdfs:seeAlso "violinID: 74" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004075 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PBT" ; rdfs:seeAlso "violinID: 75" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004076 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BoNT/F(Hc)" ; rdfs:seeAlso "violinID: 76" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004077 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BoNT/B(Hc)" ; rdfs:seeAlso "violinID: 78" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004078 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VRP" ; rdfs:seeAlso "violinID: 82" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004079 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V-LSN" ; rdfs:seeAlso "violinID: 83" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004080 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V-LSG" ; rdfs:seeAlso "violinID: 84" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004081 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V-LSG1 + V-LSG2" ; rdfs:seeAlso "violinID: 85" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004082 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V-LSG + V-LSN" ; rdfs:seeAlso "violinID: 86" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004083 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V-LSG/N" ; rdfs:seeAlso "violinID: 87" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004084 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HC of type C and D" ; rdfs:seeAlso "violinID: 88" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004085 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ML29" ; rdfs:seeAlso "violinID: 89" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004086 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V-LSGPC" ; rdfs:seeAlso "violinID: 90" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004087 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VSV[Delta]G/LVGPC" ; rdfs:seeAlso "violinID: 92" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004088 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "YFV17D/LAS-GPC" ; rdfs:seeAlso "violinID: 93" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004089 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ACAM1000" ; rdfs:seeAlso "violinID: 95" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004090 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CCSV" ; rdfs:seeAlso "violinID: 97" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004091 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LC16m8" ; rdfs:seeAlso "violinID: 98" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004092 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA" ; rdfs:seeAlso "violinID: 99" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004093 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC" ; rdfs:seeAlso "violinID: 100" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004094 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "dVV-L" ; rdfs:seeAlso "violinID: 101" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004095 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IMV-EEV" ; rdfs:seeAlso "violinID: 102" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004096 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Smallpox DNA Vaccine" ; rdfs:seeAlso "violinID: 103" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004097 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA-BN" ; rdfs:seeAlso "violinID: 106" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004098 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LC16m0" ; rdfs:seeAlso "violinID: 107" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004099 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pABFHc2" ; rdfs:seeAlso "violinID: 108" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004100 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Inactivated C. jejuni whole-cell (CWC)" ; rdfs:seeAlso "violinID: 114" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197 ] . obo:VO_0004101 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MBP fused on Campylobacter FlaA (MBP-FlaA)" ; rdfs:seeAlso "violinID: 124" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197 ] . obo:VO_0004102 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant DOBV nucleocapsid protein (rDOBV N)" ; rdfs:seeAlso "violinID: 140" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980442 ] . obo:VO_0004103 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Truncated Recombinant DoBV Nucleocapsid Proteins (Dob-N rNp)" ; rdfs:seeAlso "violinID: 141" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980442 ] . obo:VO_0004104 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VEE virus complex-specific monoclonal antibody" ; rdfs:seeAlso "violinID: 167" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004105 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Live attenuated vaccine TC-83" ; rdfs:seeAlso "violinID: 168" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004106 obo:IAO_0000117 "RS, NF, YH" ; obo:IAO_0000119 "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=172", "https://www.ncbi.nlm.nih.gov/pubmed/15196215" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA85A prime and BCG boost" ; rdfs:seeAlso "violinID: 172" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0003127 ; owl:someValuesFrom obo:VO_0003120 ] . obo:VO_0004107 obo:IAO_0000117 "RS, NF, YH" ; obo:IAO_0000119 "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=174" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BCG expressing MSP" ; rdfs:seeAlso "violinID: 174" ; rdfs:subClassOf obo:VO_0003130 . obo:VO_0004108 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mtb72f fusion protein" ; rdfs:seeAlso "violinID: 175" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004109 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant RNA replicons from attenuated VEE virus" ; rdfs:seeAlso "violinID: 181" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004110 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Nontypeable H. influenzae Outer Membrane Protein P1 vaccine" ; rdfs:seeAlso "violinID: 182" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_727 ] . obo:VO_0004111 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chimeric SIN/VEE Virus SIN-83" ; rdfs:seeAlso "violinID: 183" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004112 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Live attenuated VEE vaccines" ; rdfs:seeAlso "violinID: 184" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004113 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Live attenuated V3526 virus" ; rdfs:seeAlso "violinID: 185" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004114 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Nontypeable H. influenzae outer membrane recombinant P4 vaccine" ; rdfs:seeAlso "violinID: 187" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_727 ] . obo:VO_0004115 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Non-typeable H. influenzae dLOS-P6 vaccine" ; rdfs:seeAlso "violinID: 196" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_727 ] . obo:VO_0004116 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Defective adenovirus expressing VEEV E2 glycoprotein" ; rdfs:seeAlso "violinID: 197" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004117 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg virus-like particles" ; rdfs:seeAlso "violinID: 216" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004118 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Adenovirus vectors expressing Marburg virus glycoprotein" ; rdfs:seeAlso "violinID: 217" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004119 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA vaccine encoding ANDV glycoproteins" ; rdfs:seeAlso "violinID: 218" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980442 ] . obo:VO_0004120 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chimaeric HBV core particles carrying Puumala virus nucleocapsid protein fragments" ; rdfs:seeAlso "violinID: 219" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980442 ] . obo:VO_0004121 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avirulent Salmonella vaccine strain carrying C. jejuni cjaA gene" ; rdfs:seeAlso "violinID: 220" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197 ] . obo:VO_0004122 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BCG auxotroph expressing HIV-1 clade immunogen" ; rdfs:seeAlso "violinID: 224" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004123 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA vaccine pAK4-sod" ; rdfs:seeAlso "violinID: 225" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004124 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "deltaphoP/Q S. typhimurium strains expressing PEB1-ss" ; rdfs:seeAlso "violinID: 226" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197 ] . obo:VO_0004125 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant VEE Replicons expressing MBGV GP" ; rdfs:seeAlso "violinID: 227" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004126 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant VEE Replicons expressing MBGV NP" ; rdfs:seeAlso "violinID: 228" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004127 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Irradiated MBGV antigen" ; rdfs:seeAlso "violinID: 229" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004128 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg virus glycoprotein expressed by baculovirus recombinants" ; rdfs:seeAlso "violinID: 230" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004129 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Q-VAX" ; rdfs:seeAlso "violinID: 237" ; rdfs:subClassOf obo:VO_0000463, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_777 ] . obo:VO_0004130 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Multivalent DNA vaccine for B. anthracis, Ebola virus, Marburg virus, and VEE virus" ; rdfs:seeAlso "violinID: 238" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004131 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M-44" ; rdfs:seeAlso "violinID: 240" ; rdfs:subClassOf obo:VO_0000463, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_777 ] . obo:VO_0004132 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chloroform-methanol residue (CMR)" ; rdfs:seeAlso "violinID: 241" ; rdfs:subClassOf obo:VO_0000463, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_777 ] . obo:VO_0004133 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P1-HspB (fusion of protein 1 and heat-shock protein B)" ; rdfs:seeAlso "violinID: 242" ; rdfs:subClassOf obo:VO_0000463, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_777 ] . obo:VO_0004134 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coxevac" ; rdfs:seeAlso "violinID: 243" ; rdfs:subClassOf obo:VO_0000463, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_777 ] . obo:VO_0004135 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamyvax FQ" ; rdfs:seeAlso "violinID: 244" ; rdfs:subClassOf obo:VO_0000463, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_777 ] . obo:VO_0004136 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VSV-based vaccine expressing MBGV GP" ; rdfs:seeAlso "violinID: 245" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004137 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Heterologous MARV Protein VLP" ; rdfs:seeAlso "violinID: 246" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004138 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVD 909" ; rdfs:seeAlso "violinID: 250" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004139 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVD 915" ; rdfs:seeAlso "violinID: 253" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004140 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Broilact Chick Salmonella vaccine" ; rdfs:seeAlso "violinID: 255" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004141 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Zoosaloral H." ; rdfs:seeAlso "violinID: 256" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004142 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella vacT" ; rdfs:seeAlso "violinID: 257" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004143 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. flexneri 2a strain CVD 1205" ; rdfs:seeAlso "violinID: 261" ; rdfs:subClassOf obo:VO_0000769, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_620 ] . obo:VO_0004144 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli heat-labile enterotoxin B-subunit (LB-T) Vaccine" ; rdfs:seeAlso "violinID: 276" ; rdfs:subClassOf obo:VO_0000041, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83334 ] . obo:VO_0004145 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Shiga Toxin 2 B Subunit Vaccine" ; rdfs:seeAlso "violinID: 282" ; rdfs:subClassOf obo:VO_0000041, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83334 ] . obo:VO_0004146 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella ovis Microparticle Subunit Vaccine" ; rdfs:seeAlso "violinID: 296" ; rdfs:subClassOf obo:VO_0002925, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_236 ] . obo:VO_0004147 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Live, Attenuated Rifampin-Resistant Rough Mutants of Brucella melitensis" ; rdfs:seeAlso "violinID: 297" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004148 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA vaccine co-expressing A85A and caspase-3" ; rdfs:seeAlso "violinID: 303" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1773 ] . obo:VO_0004149 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant vaccinia A27L, D8L, and B5R Proteins with adjuvant MPL-TDM" ; rdfs:seeAlso "violinID: 305" ; rdfs:subClassOf obo:VO_0003060, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004150 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Killed Vaccinia Virus with Adjuvant NanoEmulsion" ; rdfs:seeAlso "violinID: 311" ; rdfs:subClassOf obo:VO_0003060, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0004151 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yellow Fever NS1 Protein Vaccine" ; rdfs:seeAlso "violinID: 781" ; rdfs:subClassOf obo:VO_0000123, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11089 ] . obo:VO_0004152 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vP869" ; rdfs:seeAlso "violinID: 783" ; rdfs:subClassOf obo:VO_0000123, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11089 ] . obo:VO_0004153 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella Subunit Vaccine encoding gI and gE glycoproteins" ; rdfs:seeAlso "violinID: 785" ; rdfs:subClassOf obo:VO_0000669, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10335 ] . obo:VO_0004154 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "TBEV DNA vaccine encoding E protein" ; rdfs:seeAlso "violinID: 814" ; rdfs:subClassOf obo:VO_0012190, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11084 ] . obo:VO_0004155 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseduorabies Subunit Glycoprotein C Vaccine" ; rdfs:seeAlso "violinID: 820" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0004156 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pseudorabies recombinant vector vaccine encoding gp50 and gII protein" ; rdfs:seeAlso "violinID: 827" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0004157 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Y. pestis YscF Protein Vaccine" ; rdfs:seeAlso "violinID: 886" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004158 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Y. pestis DNA vaccine encoding dfF1 Protein" ; rdfs:seeAlso "violinID: 906" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004159 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RASV expressing Y. pestis Psn" ; rdfs:seeAlso "violinID: 908" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004160 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rotavirus VP2/VP 6 Protein Vaccine" ; rdfs:seeAlso "violinID: 914" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] . obo:VO_0004161 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rotavirus VP4/VP7 Protein Vaccine" ; rdfs:seeAlso "violinID: 917" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] . obo:VO_0004162 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. yoelii DNA vaccine encoding PyHEP17 Protein" ; rdfs:seeAlso "violinID: 927" ; rdfs:subClassOf obo:VO_0002514, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004163 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. caninum DNA vaccine encoding NcSAG1 and NcSRS2, combined with recombinant NcSAG1 and NcSRS2 Proteins" ; rdfs:seeAlso "violinID: 935" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] . obo:VO_0004164 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. caninum MIC10 and p24 protein vaccine" ; rdfs:seeAlso "violinID: 946" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] . obo:VO_0004165 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CCPS-P64kR" ; rdfs:seeAlso "violinID: 953" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0004166 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. botulinum DNA vaccine pSCARSA/BHc" ; rdfs:seeAlso "violinID: 983" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0004167 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding HA of Equine influenza virus H3N8" ; rdfs:seeAlso "violinID: 991" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004168 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant vesicular stomatitis virus encoding HA from Influenza A virus (A/WSN/1933(H1N1))" ; rdfs:seeAlso "violinID: 992" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004169 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant baculovirus encoding HA from Influenza A virus (A/Puerto Rico/8/1934(H1N1))" ; rdfs:seeAlso "violinID: 995" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004170 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant vaccinia virus encoding HA from Influenza B virus (Strain B/England/222/82)" ; rdfs:seeAlso "violinID: 996" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004171 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. major DNA Vaccine encoding LACKp24, TSA, LmSTI1 and CPa" ; rdfs:seeAlso "violinID: 1000" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004172 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. major DNA Vaccine encoding SP" ; rdfs:seeAlso "violinID: 1001" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004173 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pCAGGoptiHA" ; rdfs:seeAlso "violinID: 1002" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004174 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BacHA derived from Influenza A virus (A/Indonesia/CDC669/2006(H5N1))" ; rdfs:seeAlso "violinID: 1007" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004175 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Flagellin-based HA globular head fusion vaccine using HA protein from Influenza A virus (A/Viet Nam/1203/2004(H5N1))" ; rdfs:seeAlso "violinID: 1010" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004176 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. major H1 Protein Vaccine" ; rdfs:seeAlso "violinID: 1011" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004177 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding M1 from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ; rdfs:seeAlso "violinID: 1015" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004178 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AdH5-FluA NP" ; rdfs:seeAlso "violinID: 1021" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004179 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani LD31 Protein Vaccine" ; rdfs:seeAlso "violinID: 1030" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004180 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leishmania vaccine using recombinant L. tarentolae strain expressing A2 antigen" ; rdfs:seeAlso "violinID: 1032" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004181 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. annulata Tams1 Protein Vaccine" ; rdfs:seeAlso "violinID: 1055" ; rdfs:subClassOf obo:VO_0000909, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5874 ] . obo:VO_0004182 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. typhi DnaJ Protein Vaccine" ; rdfs:seeAlso "violinID: 1056" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004183 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. typhi GroEL Protein Vaccine" ; rdfs:seeAlso "violinID: 1057" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004184 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella IroN Protein Vaccine" ; rdfs:seeAlso "violinID: 1060" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004185 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Salmonella DNA vaccine encoding SopB Protein" ; rdfs:seeAlso "violinID: 1062" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004186 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. typimurium Vi4072" ; rdfs:seeAlso "violinID: 1063" ; rdfs:subClassOf obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_590 ] . obo:VO_0004187 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles Virus vaccine VEE/SIN-H" ; rdfs:seeAlso "violinID: 1068" ; rdfs:subClassOf obo:VO_0000654, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11234 ] . obo:VO_0004188 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. burgdorferi DbpA and OspA Protein Vaccine" ; rdfs:seeAlso "violinID: 1073" ; rdfs:subClassOf obo:VO_0000764, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0004189 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. aeruginosa DNA Vaccine encoding OprF" ; rdfs:seeAlso "violinID: 1079" ; rdfs:subClassOf obo:VO_0000393, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0004190 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. aeruginosa OprI Protein Vaccine" ; rdfs:seeAlso "violinID: 1080" ; rdfs:subClassOf obo:VO_0000393, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0004191 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. aeruginosa PcrV Protein Vaccine" ; rdfs:seeAlso "violinID: 1081" ; rdfs:subClassOf obo:VO_0000393, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0004192 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. aureus DNA Vaccine encoding PBP2a Protein" ; rdfs:seeAlso "violinID: 1085" ; rdfs:subClassOf obo:VO_0002502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0004193 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum LSA-3 Protein Vaccine" ; rdfs:seeAlso "violinID: 1096" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004194 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. chabaudi AMA1 Protein Vaccine" ; rdfs:seeAlso "violinID: 1102" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004195 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum CS expressed in irradiated P. berghei as Vaccine" ; rdfs:seeAlso "violinID: 1103" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004196 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum DNA Vaccine encoding EBA-175" ; rdfs:seeAlso "violinID: 1104" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004197 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pcDNA3-LiP0" ; rdfs:seeAlso "violinID: 1106" ; rdfs:subClassOf obo:VO_0012159, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5671 ] . obo:VO_0004198 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VVr expressing L. infantum P36/LACK" ; rdfs:seeAlso "violinID: 1107" ; rdfs:subClassOf obo:VO_0012159, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5671 ] . obo:VO_0004199 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. amazonensis CP Protein Vaccine" ; rdfs:seeAlso "violinID: 1110" ; rdfs:subClassOf obo:VO_0012158, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5659 ] . obo:VO_0004200 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. agalactiae BipA Protein Vaccine" ; rdfs:subClassOf obo:VO_0001375, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1311 ] . obo:VO_0004201 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "J5dLPS/OMP" ; rdfs:seeAlso "violinID: 1118" ; rdfs:subClassOf obo:VO_0000152, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_263 ] . obo:VO_0004202 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum Tarp subunit vaccine" ; rdfs:seeAlso "violinID: 1119" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83560 ] . obo:VO_0004203 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. jejuni PorA protein vaccine" ; rdfs:seeAlso "violinID: 1120" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197 ] . obo:VO_0004204 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum pfCelTos protein vaccine" ; rdfs:seeAlso "violinID: 1121" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004205 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/806594" ; obo:VO_0003198 "806594" ; obo:VO_0003560 "acellular pertussis vaccine, inactivated / diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Boostrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364909", "RXAUI: 5027374", "TUI: T200" ; rdfs:label "BOOSTRIX vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003995 . obo:VO_0004206 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Boostrix (Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 8 MCG / Bordetella pertussis pertactin vaccine, inactivated 2.5 MCG / Bordetella pertussis toxoid vaccine, inactivated 8 MCG / diphtheria toxoid vaccine, inactivated 2.5 UNT / tetanus toxoid vaccine, inactivated 5 UNT) per 0.5 ML Prefilled Syringe", "Boostrix Tdap (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed) 0.5 ML Prefilled Syringe" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300370" ; obo:VO_0003198 "1300370" ; obo:VO_0003560 "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.016 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.016 MG/ML / diphtheria toxoid vaccine, inactivated 5 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Boostrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364910", "RXAUI: 5027662, 7253757, 4625540, 4625564", "TUI: T200" ; rdfs:label "BOOSTRIX vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0004205, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003997 ] . obo:VO_0004207 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300365" ; obo:VO_0003198 "1300365" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3474172", "RXAUI: 4625526", "TUI: T200" ; rdfs:label "Bordetella pertussis pertactin vaccine, inactivated 0.005 MG/ML" ; rdfs:subClassOf obo:VO_0003199 . obo:VO_0004208 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1368371" ; obo:VO_0003198 "1368371" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C3535682", "RXAUI: 5068281", "TUI: T116, T129, T121" ; rdfs:label "BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS" ; rdfs:subClassOf obo:VO_0000919, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000014 ] . obo:VO_0004209 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ovine Ecthyma live virus vaccine by Colorado Serum Company CZ Veterinaria" ; rdfs:seeAlso "violinID: 2074" ; rdfs:subClassOf obo:VO_0001460, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10258 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000890 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004210 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ovine Ecthyma live virus waccine by Texas Agricultural Experiment Station" ; rdfs:seeAlso "violinID: 2075" ; rdfs:subClassOf obo:VO_0001460, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10258 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000269 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004211 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "West Nile Virus DNA Vaccine (USDA: 1995.D0)" ; rdfs:seeAlso "violinID: 2149" ; rdfs:subClassOf obo:VO_0000752, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000701 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004212 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine Parainfluenza Modified Live Virus Vaccine-Leptospira Canicola-Icterohaemorrhagiae Bacterin (USDA: 47A9.20)" ; rdfs:seeAlso "violinID: 2736; violinID: 2737" ; rdfs:subClassOf obo:VO_0000391, obo:VO_0000586, obo:VO_0001526, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_149595 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000204 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004213 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799961" ; obo:VO_0003198 "1799961" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C4271790", "RXAUI: 8235199", "TUI: T200" ; rdfs:label "BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0004208 . obo:VO_0004214 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine-Erysipelothrix Rhusiopathiae-Haemophilus Parasuis Bacterin (USDA: 49V9.20)" ; rdfs:seeAlso "violinID: 2979; violinID: 2980; violinID: 2981" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001802, obo:VO_0003535, obo:VO_0003554, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1648 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_738 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004215 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1174360" ; obo:VO_0003198 "1174360" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3228377", "RXAUI: 3830942", "TUI: T200" ; rdfs:label "Biothrax Injectable Product" ; rdfs:subClassOf obo:VO_0000014 . obo:VO_0004216 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1799963" ; obo:VO_0003198 "1799963" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4271638", "RXAUI: 8235201", "TUI: T200" ; rdfs:label "BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 0.1 MG/ML [Biothrax]" ; rdfs:subClassOf obo:VO_0000014, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004213 ] . obo:VO_0004217 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine-Haemophilus Parasuis Bacterin (USDA: 49Q9.20)" ; rdfs:seeAlso "violinID: 2982; violinID: 2983" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0001802, obo:VO_0003535, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_738 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000901 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004218 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/832681" ; obo:VO_0003198 "832681" ; obo:VO_0003560 "Anthrax Vaccine Adsorbed Injectable Suspension [Biothrax]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2608510", "RXAUI: 2943547", "TUI: T200" ; rdfs:label "Biothrax Injectable Suspension" ; rdfs:subClassOf obo:VO_0004215 . obo:VO_0004219 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine encoding MIC8" ; rdfs:seeAlso "violinID: 3038" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004220 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. aureus IsdB subunit vaccine (V710)" ; rdfs:seeAlso "violinID: 3039" ; rdfs:subClassOf obo:VO_0002502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0004221 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. multocida rOmpH Vaccine" ; rdfs:seeAlso "violinID: 3040" ; rdfs:subClassOf obo:VO_0000620, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ] . obo:VO_0004222 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Inactivated PMV-3 Vaccine with Specol" ; rdfs:seeAlso "violinID: 3046" ; rdfs:subClassOf obo:VO_0001527, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_260963 ] . obo:VO_0004223 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis rPA Vaccine with Rehydragel HPA adjuvant" ; rdfs:seeAlso "violinID: 3047" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004224 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rotavirus Chimeric VP6 protein Vaccine" ; rdfs:seeAlso "violinID: 3048" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] . obo:VO_0004225 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BHV1 gD subunit vaccine" ; rdfs:seeAlso "violinID: 3050" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0004226 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BVDV Inactivated Vaccine" ; rdfs:seeAlso "violinID: 3051" ; rdfs:subClassOf obo:VO_0001501, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11099 ] . obo:VO_0004227 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:9725239", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3053" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/369" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "3053" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7" ; rdfs:label "Cancer Vaccine using E7 protein of human papillomavirus 16 and Algammulin" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004228 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:10931134", "PubMed:9725239", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3054" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/370" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "3054" ; obo:VO_0005500 "Licensed" ; a owl:Class ; rdfs:comment "Gene name: E7" ; rdfs:label "Cancer Vaccine using E7 protein of human papillomavirus 16 and Quil-A" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0004229 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. maxima oocysts with Arlacel A vaccine" ; rdfs:seeAlso "violinID: 3056" ; rdfs:subClassOf obo:VO_0001125, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5804 ] . obo:VO_0004230 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tetanus Toxoid with Calcium Phosphate" ; rdfs:seeAlso "violinID: 3057" ; rdfs:subClassOf obo:VO_0000640, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] . obo:VO_0004231 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tetanus Toxoid with Stearyl Tyrosine" ; rdfs:seeAlso "violinID: 3058" ; rdfs:subClassOf obo:VO_0000640, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] . obo:VO_0004232 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V3 VLPs with Gamma inulin adjuvant" ; rdfs:seeAlso "violinID: 3059" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004233 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "gp120 recominant with GMDP adjuvant" ; rdfs:seeAlso "violinID: 3061" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004234 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "gp120 recominant with MDP adjuvant" ; rdfs:seeAlso "violinID: 3062" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004235 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rHA with IL-1Beta adjuvant" ; rdfs:seeAlso "violinID: 3063" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004236 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rHA with IL-2 adjuvant" ; rdfs:seeAlso "violinID: 3064" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004237 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rHA with IL-7 adjuvant" ; rdfs:seeAlso "violinID: 3065" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004238 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "gp140, Gag and Tat Protein Vaccine with MF59" ; rdfs:seeAlso "violinID: 3067" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004239 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HBsAg Liposomal MTP-PE Vaccine" ; rdfs:seeAlso "violinID: 3068" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004240 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Synthetic OMP1 Vaccine" ; rdfs:seeAlso "violinID: 3069" ; rdfs:subClassOf obo:VO_0001207, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_813 ] . obo:VO_0004241 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani Recombinant Ld-Gamma-GCS in NIV system Vaccine" ; rdfs:seeAlso "violinID: 3070" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004242 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Inactivated HIV-2 Vaccine with PMMA" ; rdfs:seeAlso "violinID: 3071" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004243 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum MSP4 with AFCo1 Adjuvant" ; rdfs:seeAlso "violinID: 3072" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004244 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Inactivated split Mem 71 Virus with SPT adjuvant" ; rdfs:seeAlso "violinID: 3073" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004245 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3074" ; obo:VO_0001818 "3074" ; a owl:Class ; rdfs:label "Recombinant Colorectal cancer antigen GA733 Vaccine" ; rdfs:subClassOf obo:VO_0005426, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9256 ] . obo:VO_0004246 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Anthrax vaccine adsorbed with Squalene adjuvant" ; rdfs:seeAlso "violinID: 3076" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004247 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Group A streptococcal recombinant fusion peptide Vaccine" ; rdfs:seeAlso "violinID: 3077" ; rdfs:subClassOf obo:VO_0002852, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] . obo:VO_0004248 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3078" ; obo:VO_0001818 "3078" ; a owl:Class ; rdfs:label "Recombinant NY-ESO-1 Protein vaccine adjuvanted with Imiquimod" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004249 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mutagrip Vaccine with P40 Adjuvant" ; rdfs:seeAlso "violinID: 3080" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004250 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:28706878", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3081" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/241" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "3081" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7" ; rdfs:label "attenuated Listeria expressing cancer antigen vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000416 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004251 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant S gene Hepatitis B Vaccine with rIFN-gamma" ; rdfs:seeAlso "violinID: 3082" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004252 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Y. pestis F1 antigen Vaccine with Flagellin" ; rdfs:seeAlso "violinID: 3083" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004253 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Inactivated H1N1(2009) Vaccine with AF03 adjuvant" ; rdfs:seeAlso "violinID: 3084" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004254 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3085" ; obo:VO_0001818 "3085" ; a owl:Class ; rdfs:label "Recombinant NY-ESO-1 ISCOMATRIX Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004255 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant PA with Poly(I:C) Adjuvant" ; rdfs:seeAlso "violinID: 3086" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004256 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant Tir Protein Vaccine" ; rdfs:seeAlso "violinID: 3087" ; rdfs:subClassOf obo:VO_0000041, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83334 ] . obo:VO_0004257 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum PmpG-1, PmpE/F-2, and MOMP Proteins Vaccine" ; rdfs:seeAlso "violinID: 3089" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83560 ] . obo:VO_0004258 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3091" ; obo:VO_0001818 "3091" ; a owl:Class ; rdfs:label "Synthetic MUC1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0004259 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV-2 DNA vaccine" ; rdfs:seeAlso "violinID: 3092" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004260 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B surface antigen (HBsAg) with JVRS-1000" ; rdfs:seeAlso "violinID: 3093" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004261 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "live TC-83 VEE Vaccine with DHEA" ; rdfs:seeAlso "violinID: 3094" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004262 obo:IAO_0000117 "RS, NF, YH" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000933 ; a owl:Class ; rdfs:label "obsolete E. coli CS3 in PLGA microspheres" ; rdfs:seeAlso "violinID: 3095" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0004263 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA/IL-15/5Mtb vaccine" ; rdfs:seeAlso "violinID: 3096" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004264 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rgp120 HIV Vaccine with immunoliposomes" ; rdfs:seeAlso "violinID: 3097" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004265 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal polysaccharide conjugate vaccine serotype 1 (PNC-1)" ; rdfs:seeAlso "violinID: 3098" ; rdfs:subClassOf obo:VO_0003284, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004266 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LEISH-F1+MPL-SE vaccine" ; rdfs:seeAlso "violinID: 3099" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004267 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HSV glycoproteins subunit vaccine" ; rdfs:seeAlso "violinID: 3100" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004268 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV-1 gp120 with mCT E112K" ; rdfs:seeAlso "violinID: 3101" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004269 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum MSA-2 subunit vaccine" ; rdfs:seeAlso "violinID: 3103" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004270 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis PA protein Vaccine with TMDP" ; rdfs:seeAlso "violinID: 3104" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004271 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. yoelii TyCS-VLP Vaccine" ; rdfs:seeAlso "violinID: 3105" ; rdfs:subClassOf obo:VO_0002514, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004272 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pVAX-P1 DNA vaccine" ; rdfs:seeAlso "violinID: 3106" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004273 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "YopE(67-77) Protein Vaccine" ; rdfs:seeAlso "violinID: 3107" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004274 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV recombinant gp160 Protein Vaccine" ; rdfs:seeAlso "violinID: 3108" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004275 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "human apo B-100 peptide-2 protein vaccine" ; rdfs:seeAlso "violinID: 3110" ; rdfs:subClassOf obo:VO_0002793 . obo:VO_0004276 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MDA-modified human apo B-100 peptide Vaccine" ; rdfs:seeAlso "violinID: 3111" ; rdfs:subClassOf obo:VO_0002793 . obo:VO_0004277 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella melitensis mucR mutant vaccine" ; rdfs:seeAlso "violinID: 3117" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004278 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tick-borne Encephalitis Virus C protein mutant vaccine" ; rdfs:seeAlso "violinID: 3147" ; rdfs:subClassOf obo:VO_0012190, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11084 ] . obo:VO_0004279 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycobacterium tuberculosis mce-2 mutant vaccine" ; rdfs:seeAlso "violinID: 3207" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004280 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Aflunov" ; rdfs:seeAlso "violinID: 3285" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000971 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004281 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluad" ; rdfs:seeAlso "violinID: 3286" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000971 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004282 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Focetria" ; rdfs:seeAlso "violinID: 3287" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000971 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004283 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Brucella abortus S19 vjbR mutant vaccine" ; rdfs:seeAlso "violinID: 3288" ; rdfs:subClassOf obo:VO_0000108, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_235 ] . obo:VO_0004284 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "African Swine Fever Virus 9GL mutant vaccine" ; rdfs:seeAlso "violinID: 3289" ; rdfs:subClassOf obo:VO_0001211, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10497 ] . obo:VO_0004285 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant B. abortus CobB protein with CFA/IFA adjuvant" ; rdfs:seeAlso "violinID: 3292" ; rdfs:subClassOf obo:VO_0000108, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004286 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant B. abortus AsnC protein with CFA/IFA adjuvant" ; rdfs:seeAlso "violinID: 3293" ; rdfs:subClassOf obo:VO_0000108, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004287 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M2 mutant from Influenza A" ; rdfs:seeAlso "violinID: 3294" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004288 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mycobacterium tuberculosis mce-3 mutant vaccine" ; rdfs:seeAlso "violinID: 3296" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004289 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine Respiratory Syncytial Virus recombinant vector vaccine BHVl/BRSVG encoding the G protein" ; rdfs:seeAlso "violinID: 3299" ; rdfs:subClassOf obo:VO_0001507, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11246 ] . obo:VO_0004290 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine BacPAKHA encoding EqfKY HA" ; rdfs:seeAlso "violinID: 3301" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004291 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine p188 encoding H7" ; rdfs:seeAlso "violinID: 3303" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004292 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pCMV/Hl encoding H1" ; rdfs:seeAlso "violinID: 3304" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004293 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pCMV/H7" ; rdfs:seeAlso "violinID: 3305" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004294 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pIRES/HA encoding HA" ; rdfs:seeAlso "violinID: 3306" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004295 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pIRES/NA expressing NA" ; rdfs:seeAlso "violinID: 3307" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004296 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pIRES/HA/IL-2 expressing HA" ; rdfs:seeAlso "violinID: 3308" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004297 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pIRES/NA/IL-2 encoding NA" ; rdfs:seeAlso "violinID: 3309" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004298 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pIRES/HA/GM-CSF encoding HA" ; rdfs:seeAlso "violinID: 3310" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004299 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pIRES/NA/GM-CSF encoding NA" ; rdfs:seeAlso "violinID: 3311" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004300 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pIRES/HA/IL-12p35 + pIRES/NA/IL-12p40" ; rdfs:seeAlso "violinID: 3312" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004301 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pRSV-NP encoding the coding sequence from influenza virus A/PR/8/34." ; rdfs:seeAlso "violinID: 3316" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004302 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pHA/NP147-155 encoding NP147-155" ; rdfs:seeAlso "violinID: 3318" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004303 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pBK-SFV-NP" ; rdfs:seeAlso "violinID: 3320" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004304 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pBK-SFV-HA" ; rdfs:seeAlso "violinID: 3322" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004305 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine HA-DNA" ; rdfs:seeAlso "violinID: 3324" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004306 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine d1TTFC-NP encoding NP" ; rdfs:seeAlso "violinID: 3327" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004307 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine A/NP" ; rdfs:seeAlso "violinID: 3330" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004308 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine NP DNA" ; rdfs:seeAlso "violinID: 3331" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004309 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine HA DNA" ; rdfs:seeAlso "violinID: 3332" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004310 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine NA-DNA" ; rdfs:seeAlso "violinID: 3333" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004311 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine H5 DNA" ; rdfs:seeAlso "violinID: 3338" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004312 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine pSAG1-ROP2-SAG2" ; rdfs:seeAlso "violinID: 3342" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004313 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine pcDNA3.1-SAG1-ROP2" ; rdfs:seeAlso "violinID: 3343" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004314 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Y. pestis DNA vaccine F1-V DNA" ; rdfs:seeAlso "violinID: 3344" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004315 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 DNA vaccine pRSVgIV" ; rdfs:seeAlso "violinID: 3349" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0004316 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 recombinant vector vaccine BHVl/BRSVG" ; rdfs:seeAlso "violinID: 3350" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0004317 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 DNA vaccine pMASIAtgB encoding a truncated, secreted form of gB" ; rdfs:seeAlso "violinID: 3357" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0004318 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 recombinant vector vaccine rLaSota/gDFL encoding gD" ; rdfs:seeAlso "violinID: 3359" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0004319 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 recombinant vector vaccine rLaSota/gDF encoding gD" ; rdfs:seeAlso "violinID: 3360" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10320 ] . obo:VO_0004320 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Foot and mouth disease DNA vaccine pWRMHX encoding a minimal self-cleaving ribozyme" ; rdfs:seeAlso "violinID: 3366" ; rdfs:subClassOf obo:VO_0001213, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12110 ] . obo:VO_0004321 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IHNV DNA vaccine pCMV4-G" ; rdfs:seeAlso "violinID: 3369" ; rdfs:subClassOf obo:VO_0012165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11290 ] . obo:VO_0004322 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IHNV DNA vaccine pCMV4-N encoding the nucleoprotein" ; rdfs:seeAlso "violinID: 3370" ; rdfs:subClassOf obo:VO_0012165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11290 ] . obo:VO_0004323 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Murine cytomegalovirus DNA vaccine pcDNA-89 encoding pp89" ; rdfs:seeAlso "violinID: 3372" ; rdfs:subClassOf obo:VO_0003062, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10366 ] . obo:VO_0004324 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle disease virus DNA vaccine pCAGF encoding the F protein" ; rdfs:seeAlso "violinID: 3373" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560319 ] . obo:VO_0004325 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PRRSV DNA vaccine GST-ORF5 encoding GP5" ; rdfs:seeAlso "violinID: 3374" ; rdfs:subClassOf obo:VO_0001802, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0004326 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies virus DNA vaccine pSG5rab.gp" ; rdfs:seeAlso "violinID: 3375" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004327 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lymphocytic choriomeningitis virus DNA vaccine pCMV-NP" ; rdfs:seeAlso "violinID: 3376" ; rdfs:subClassOf obo:VO_0001216, obo:VO_0003044, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052303 ] . obo:VO_0004328 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus DNA vaccine VlJns-Ll encoding L1" ; rdfs:seeAlso "violinID: 3379" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0004329 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus DNA vaccine Pe7(pcDNA3-Sig/sE7/LAMP) encoding E7" ; rdfs:seeAlso "violinID: 3380" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0004330 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus DNA vaccine pC16-L1 encoding L1" ; rdfs:seeAlso "violinID: 3383" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0004331 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus DNA vaccine CRT/E7 DNA" ; rdfs:seeAlso "violinID: 3384" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0004332 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus DNA vaccine E7IR" ; rdfs:seeAlso "violinID: 3388" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0004333 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus DNA vaccine E7SH DNA" ; rdfs:seeAlso "violinID: 3389" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0004334 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus DNA vaccine GP DNA" ; rdfs:seeAlso "violinID: 3392" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004335 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus recombinant rAD-GP encoding GP" ; rdfs:seeAlso "violinID: 3393" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004336 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus recombinant VSVdelta¬ùG-GP encoding GP" ; rdfs:seeAlso "violinID: 3394" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004337 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus recombinant vector vaccine EBO7 encoding GP from SEBOV and ZEBOV" ; rdfs:seeAlso "violinID: 3395" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004338 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VHSV DNA vaccine pCMV-vhsG encoding glycoprotein G" ; rdfs:seeAlso "violinID: 3396" ; rdfs:subClassOf obo:VO_0001224, obo:VO_0003056, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11287 ] . obo:VO_0004339 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VHSV DNA vaccine pCMV-vhsN encoding nucleocapsid protein N and glycoprotein G" ; rdfs:seeAlso "violinID: 3397" ; rdfs:subClassOf obo:VO_0001224, obo:VO_0003056, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11287 ] . obo:VO_0004340 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Classical swine fever virus DNA vaccine pCI-gp55" ; rdfs:seeAlso "violinID: 3398" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11096 ] . obo:VO_0004341 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human cytomegalovirus DNA vaccine VCL-CB01 encoding phosphoprotein 65 and gB" ; rdfs:seeAlso "violinID: 3401" ; rdfs:subClassOf obo:VO_0001227, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10359 ] . obo:VO_0004342 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV DNA vaccine Ad26/Ad5HVR48 encoding HIV or SIV env or gag" ; rdfs:seeAlso "violinID: 3426" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004343 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SIV DNA vaccine pVacc4 encoding env from mac239" ; rdfs:seeAlso "violinID: 3430" ; rdfs:subClassOf obo:VO_0000751, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11723 ] . obo:VO_0004344 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV DNA vaccine SHIV-89.6 DNA (DNA/89.6)" ; rdfs:seeAlso "violinID: 3439" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004345 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV DNA vaccine pCMN160" ; rdfs:seeAlso "violinID: 3449" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004346 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SIV DNA vaccine pSIVgag and pmacIL-15 encoding SIV core protein" ; rdfs:seeAlso "violinID: 3468" ; rdfs:subClassOf obo:VO_0000751, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11723 ] . obo:VO_0004347 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV recombinant vector vaccine MVA-gag encoding gag" ; rdfs:seeAlso "violinID: 3478" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004348 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV DNA vaccine pHIS-SHIV-B" ; rdfs:seeAlso "violinID: 3481" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004349 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV DNA vaccine SIVmac239 Gag-Pol-Nef and mock Env with rAd5 boost" ; rdfs:seeAlso "violinID: 3485" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004350 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV recombinant vector vaccine MVA.HIVA encoding env and rev" ; rdfs:seeAlso "violinID: 3491" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004351 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HIV DNA vaccine VlJns-tPA-gp120" ; rdfs:seeAlso "violinID: 3497" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004352 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B DNA vaccine PLGA-CTAB-DNA encoding the small envelope gene" ; rdfs:seeAlso "violinID: 3510" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004353 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Duck hepatitis B DNA vaccine pcDNA I-S encoding small S proteins" ; rdfs:seeAlso "violinID: 3516" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004354 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B DNA vaccine pRc/CMV-HBs(S) encoding HBsAg" ; rdfs:seeAlso "violinID: 3519" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004355 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pDNA encoding M2 and NP" ; rdfs:seeAlso "violinID: 3520" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004356 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA vaccine pcDNA3.1+/Ag85A DNA encoding Ag85A" ; rdfs:seeAlso "violinID: 3522" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004357 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B DNA vaccine pS encoding major envelope proteins" ; rdfs:seeAlso "violinID: 3524" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004358 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B DNA vaccine pCMV-HBs encoding HBsAg" ; rdfs:seeAlso "violinID: 3525" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004359 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B DNA vaccine pCEA/HBsAg encoding CEA and HBsAg" ; rdfs:seeAlso "violinID: 3528" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004360 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B DNA vaccine pCMV-S2.S encoding the HBV(ayw Strain) envelope protein." ; rdfs:seeAlso "violinID: 3533" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0004361 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coxsackievirus DNA vaccine pCMV/VPl encoding VP1" ; rdfs:seeAlso "violinID: 3538" ; rdfs:subClassOf obo:VO_0001228, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12066 ] . obo:VO_0004362 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA vaccine encoding Ag85B, MPT64 and MPT83" ; rdfs:seeAlso "violinID: 3540" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004363 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA vaccine (containing the ESAT-6, MPT-64, MPT-83, and KatG constructs)" ; rdfs:seeAlso "violinID: 3546" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004364 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA vaccine DNAAg85A encoding a single immunogenic M.tb Ag" ; rdfs:seeAlso "violinID: 3547" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004365 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus DNA vaccine gD-2 encoding gD" ; rdfs:seeAlso "violinID: 3548" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004366 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus DNA vaccine Delta-gB-2 encoding gB" ; rdfs:seeAlso "violinID: 3549" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004367 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus DNA vaccine ICP-27 DNA encoding ICP-27" ; rdfs:seeAlso "violinID: 3550" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004368 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus DNA vaccine gB-DNA encoding gB" ; rdfs:seeAlso "violinID: 3551" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004369 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus DNA vaccine gBDNA encoding gB" ; rdfs:seeAlso "violinID: 3552" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004370 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus DNA vaccine encoding gD and gB from HSV-2 strain Curtis" ; rdfs:seeAlso "violinID: 3553" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004371 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies virus DNA vaccine pCMV-intA-rabies encoding glycoprotein G" ; rdfs:seeAlso "violinID: 3555" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004372 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies virus DNA vaccine encoding the ERA glycoprotein" ; rdfs:seeAlso "violinID: 3556" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004373 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leishmania major DNA vaccine KMP-11" ; rdfs:seeAlso "violinID: 3557" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004374 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine encoding TSA-1, ASP-1, ASP-2" ; rdfs:seeAlso "violinID: 3558" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5693 ] . obo:VO_0004375 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine encoding ASP-2" ; rdfs:seeAlso "violinID: 3559" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5693 ] . obo:VO_0004376 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine pUB-ASP-2" ; rdfs:seeAlso "violinID: 3560" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5693 ] . obo:VO_0004377 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine pTS encoding T. cruzi antigens" ; rdfs:seeAlso "violinID: 3561" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5693 ] . obo:VO_0004378 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lassa fever virus recombinant vector vaccine V-LSG encoding the glycoprotein" ; rdfs:seeAlso "violinID: 3565" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004379 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lassa fever virus recombinant vector vaccine V-LSG/N encoding the glycoprotein and the nucleoprotein" ; rdfs:seeAlso "violinID: 3567" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004380 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lassa fever virus recombinant vector vaccine YFV17D/LASV-GPC encoding the glycoprotein precursor" ; rdfs:seeAlso "violinID: 3570" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0004381 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus recombinant vector vaccine pVSVXN2-Delta-G/ZEBOVsGP encoding GP" ; rdfs:seeAlso "violinID: 3574" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004382 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus recombinant adenovirus vaccine AdC7-ZGP encoding GP" ; rdfs:seeAlso "violinID: 3579" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004383 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus recombinant vector vaccine Ad-CMVZGP encoding the glycoprotein" ; rdfs:seeAlso "violinID: 3580" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004384 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus recombinant vector vaccine Ad-CAGoptZGP encoding the envelope glycoprotein" ; rdfs:seeAlso "violinID: 3581" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004385 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus DNA vaccine DNA/rAd5 encoding ZEBOV and SEBOV antigens" ; rdfs:seeAlso "violinID: 3591" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004386 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine PA" ; rdfs:seeAlso "violinID: 3593" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004387 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg virus DNA vaccine MARV GP encoding GP" ; rdfs:seeAlso "violinID: 3594" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004388 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg virus recombinant vector vaccine CAdVax-Panfilo" ; rdfs:seeAlso "violinID: 3596" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004389 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg virus DNA prime/boost vaccine DNA/rAd5-GP encoding GP from strain Angola" ; rdfs:seeAlso "violinID: 3598" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004390 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg virus DNA vaccine DNA-GP encoding GP" ; rdfs:seeAlso "violinID: 3599" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004391 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg virus recombinant vector vaccine MBGV GP" ; rdfs:seeAlso "violinID: 3600" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004392 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. abortus DNA vaccine pcDNA3.1-p39-L7/L12 encoding p39-L7/L12 fusion protein" ; rdfs:seeAlso "violinID: 3605" ; rdfs:subClassOf obo:VO_0000108, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004393 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. abortus DNA vaccine pcDNA3-SOD encoding Cu-Zn SOD" ; rdfs:seeAlso "violinID: 3607" ; rdfs:subClassOf obo:VO_0000108, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004394 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis DNA vaccine pCI-Omp31" ; rdfs:seeAlso "violinID: 3611" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004395 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis DNA vaccine pCIBLSOmp31 encoding BLSOmp31 (fusion protein)" ; rdfs:seeAlso "violinID: 3613" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004396 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis DNA vaccine p-Omp25" ; rdfs:seeAlso "violinID: 3615" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004397 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. melitensis DNA vaccine p-ialB" ; rdfs:seeAlso "violinID: 3616" ; rdfs:subClassOf obo:VO_0000709, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004398 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3617" ; obo:VO_0001818 "3617" ; oboInOwl:hasAlternativeId "VO:0007471" ; a owl:Class ; rdfs:label "Lymphoma DNA vaccine V-Alpha-V-Beta-V-Beta-FrC" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ] . obo:VO_0004399 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum recombinant vector vaccine MVA.ME-TRAP" ; rdfs:seeAlso "violinID: 3628" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004400 obo:IAO_0000115 "An autologous dendritic cell vaccine with potential immunostimulatory activity. Dendritic cells harvested from a prostate cancer patient are transfected with the mRNA encoding for prostate specific antigen (PSA), a tumor marker secreted by prostatic epithelial and ductal cells. When reintroduced back to the patient, these PSA RNA pulsed autologous dendritic cells may elicit a cytotoxic T-cell (CTL) response against PSA-positive prostate cancer cells. " ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3643" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/175" ; obo:VO_0001818 "3643" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Glypican-3-derived peptide vaccine for human hepatocellular carcinoma" ; rdfs:subClassOf obo:VO_0005499, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_684 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004401 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EAE DNA vaccine pZZ/MBP68-85 encoding MBP" ; rdfs:seeAlso "violinID: 3647" ; rdfs:subClassOf obo:VO_0002837 . obo:VO_0004402 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EAU DNA vaccine IRBP-DNA encoding IRBP" ; rdfs:seeAlso "violinID: 3649" ; rdfs:subClassOf obo:VO_0002837 . obo:VO_0004403 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Autoimmune diabetes DNA vaccine pND2-SGAD55" ; rdfs:seeAlso "violinID: 3652" ; rdfs:subClassOf obo:VO_0002811 . obo:VO_0004404 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Autoimmune diabetes DNA vaccine pCMV-1/rGAD65 encoding GAD" ; rdfs:seeAlso "violinID: 3653" ; rdfs:subClassOf obo:VO_0002811 . obo:VO_0004405 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Autoimmune diabetes DNA vaccine pND2-GAD65-BAX encoding GAD and BAX" ; rdfs:seeAlso "violinID: 3655" ; rdfs:subClassOf obo:VO_0002811 . obo:VO_0004406 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Insulin-dependent diabetes mellitus DNA vaccine JwGAD65 + IL-4" ; rdfs:seeAlso "violinID: 3656" ; rdfs:subClassOf obo:VO_0002811 . obo:VO_0004407 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Adjuvant arthritis DNA vaccine pCMV3.65 encoding HSP65" ; rdfs:seeAlso "violinID: 3661" ; rdfs:subClassOf obo:VO_0002823 . obo:VO_0004408 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pristane-induced arthritis DNA vaccine DNA-hsp65 encoding Mycobacterium leprae 65-kDa heat shock protein" ; rdfs:seeAlso "violinID: 3662" ; rdfs:subClassOf obo:VO_0002823 . obo:VO_0004409 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Adjuvant arthritis DNA vaccine CII encoding type II collagen" ; rdfs:seeAlso "violinID: 3663" ; rdfs:subClassOf obo:VO_0002823 . obo:VO_0004410 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Adjuvant arthritis DNA vaccine pcDNA-CCOL2A1 encoding type II collagen" ; rdfs:seeAlso "violinID: 3664" ; rdfs:subClassOf obo:VO_0002823 . obo:VO_0004411 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus DNA vaccine pSIN-gB encoding gB" ; rdfs:seeAlso "violinID: 3665" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004412 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus DNA vaccine pCI-gB encoding gB" ; rdfs:seeAlso "violinID: 3666" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004413 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. burgdorferi DNA vaccine pCMV-ZS7/TPA encoding OspC from Borrelia burgdorferi sensu lato" ; rdfs:seeAlso "violinID: 3669" ; rdfs:subClassOf obo:VO_0000764, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0004414 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. tetani DNA vaccine pcDNA3tetC encoding fragment C" ; rdfs:seeAlso "violinID: 3672" ; rdfs:subClassOf obo:VO_0000640, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] . obo:VO_0004415 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "West Nile virus DNA vaccine pCBWN encoding prM and E" ; rdfs:seeAlso "violinID: 3673" ; rdfs:subClassOf obo:VO_0000752, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] . obo:VO_0004416 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine pDNA encoding PA" ; rdfs:seeAlso "violinID: 3677" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004417 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine LF pDNA encoding LF" ; rdfs:seeAlso "violinID: 3678" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004418 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. acervulina DNA vaccine 3-1E" ; rdfs:seeAlso "violinID: 3681" ; rdfs:subClassOf obo:VO_0000906, obo:VO_0001459, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5800 ] . obo:VO_0004419 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. rhabdovirus DNA vaccine pHRV-G encoding HIRRV and VHSV G proteins" ; rdfs:seeAlso "violinID: 3682" ; rdfs:subClassOf obo:VO_0002455, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980915 ] . obo:VO_0004420 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IHNV DNA vaccine pCDNA-G encoding G" ; rdfs:seeAlso "violinID: 3687" ; rdfs:subClassOf obo:VO_0012165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11290 ] . obo:VO_0004421 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VEE virus DNA vaccine VEEV IA/B parent encoding structural genes" ; rdfs:seeAlso "violinID: 3689" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004422 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VEE virus recombinant vector vaccine RAd/VEEV" ; rdfs:seeAlso "violinID: 3690" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004423 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VEE virus recombinant vector vaccine RAd/VEEV#2" ; rdfs:seeAlso "violinID: 3691" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004424 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VEE virus recombinant vector vaccine RAd/VEEV#3 encoding TC-83" ; rdfs:seeAlso "violinID: 3692" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004425 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15879128", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3695" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/316" ; obo:OGG_0000000006 "8132375" ; obo:VO_0001818 "3695" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: Fragment C from tetanus toxin" ; rdfs:label "Cancer DNA vaccine p.DOM-AH1 encoding fragment C" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004426 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:18273615", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3696" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/378" ; obo:OGG_0000000006 "21423" ; obo:VO_0001818 "3696" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: E2A" ; rdfs:label "Carcinoma DNA vaccine pVAX/E2A" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004427 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:12384547", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3698" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/292" ; obo:OGG_0000000006 "1945467" ; obo:VO_0001818 "3698" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Immunoglobulin" ; rdfs:label "B-cell lymphoma DNA vaccine VCL-1642.XXX encoding a chimeric immunoglobulin molecule onsisting of tumor-specific variable (Id) regions" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004428 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:12231517", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3699" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/387" ; obo:OGG_0000000006 "1048", "128168861" ; obo:VO_0001818 "3699" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: S|CEA" ; rdfs:label "Colorectal cancer DNA vaccine pCEA/HBsAg encoding carcinoembryonic antigen and hepatitis B surface antigen" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004429 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:12496961", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3700" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/294" ; obo:OGG_0000000006 "22178", "7306" ; obo:VO_0001818 "3700" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: TYRP1|Gene name: Tyrp1" ; rdfs:label "B16 melanoma DNA vaccine pSin-hTRP-1 encoding TRP-1" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0004430 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:12496961", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3701" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/293" ; obo:OGG_0000000006 "22178", "7306" ; obo:VO_0001818 "3701" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: TYRP1|Gene name: Tyrp1" ; rdfs:label "B16 melanoma DNA vaccine pCMV-hTRP-1 encoding TRP-1" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0004431 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3705" ; obo:VO_0001818 "3705" ; a owl:Class ; rdfs:label "Melanoma DNA vaccine TA2M encoding tyrosinase peptides" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004432 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3713" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/518" ; obo:VO_0001818 "3713" ; a owl:Class ; rdfs:comment "Gene name: Survivin" ; rdfs:label "Melanoma DNA vaccine VR-S8/VR-IL2/AD-S8 encoding survivin" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004433 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3717" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/512" ; obo:OGG_0000000006 "2922" ; obo:VO_0001818 "3717" ; a owl:Class ; rdfs:comment "Gene name: GRP" ; rdfs:label "Melanoma DNA vaccine pCR3.1-VS-HSP65-TP-GRP6-M2 encoding 6 tandem repeats of GRP" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004434 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3718" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/514" ; obo:OGG_0000000006 "12981", "4100" ; obo:VO_0001818 "3718" ; a owl:Class ; rdfs:comment "Gene name: GM-CSF|Gene name: MAGEA1" ; rdfs:label "Melanoma DNA vaccine pNL3-MAGE-1-GM" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004435 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3719" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/513" ; obo:OGG_0000000006 "12981", "4100" ; obo:VO_0001818 "3719" ; a owl:Class ; rdfs:comment "Gene name: GM-CSF|Gene name: MAGEA1" ; rdfs:label "Melanoma DNA vaccine pN4a-MAGE-1-GM" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004436 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3720" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/516" ; obo:OGG_0000000006 "84004" ; obo:VO_0001818 "3720" ; a owl:Class ; rdfs:comment "Gene name: Mcam" ; rdfs:label "Melanoma DNA vaccine SINCp c-muMUC18 encoding MCAM/MUC18" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004437 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3723" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/485" ; obo:OGG_0000000006 "17829", "4582" ; obo:VO_0001818 "3723" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1|Gene name: Muc1" ; rdfs:label "Lung metastasis DNA vaccine pCEP4-MUC1 encoding MUC1" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004438 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3724" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/511" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "3724" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "Melanoma DNA vaccine hugp100 encoding gp100" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004439 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3726" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/519" ; obo:OGG_0000000006 "20431" ; obo:VO_0001818 "3726" ; a owl:Class ; rdfs:comment "Gene name: Pmel17" ; rdfs:label "Melanoma DNA vaccine VR1012/mPmel17" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004440 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3727" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/509" ; obo:OGG_0000000006 "1067130", "1638" ; obo:VO_0001818 "3727" ; a owl:Class ; rdfs:comment "Gene name: HUMGP 75|Gene name: TRP-2" ; rdfs:label "Melanoma DNA vaccine gp75 DNA encoding melanosomal membrane glycoproteins, gp75 Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004441 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3728" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/521" ; obo:OGG_0000000006 "22178" ; obo:VO_0001818 "3728" ; a owl:Class ; rdfs:comment "Gene name: TRP-1" ; rdfs:label "Melanoma recombinant vector vaccine rVVmTRP-1 encoding TRP-1" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000416 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004442 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3729" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/510" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "3729" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "Melanoma DNA vaccine hTRP2 encoding TRP-2" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004443 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3730" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/515" ; obo:OGG_0000000006 "104042", "55118" ; obo:VO_0001818 "3730" ; a owl:Class ; rdfs:comment "Gene name: Ubiquitin|Gene name: Trp2" ; rdfs:label "Melanoma DNA vaccine pUB-TRP-2 encoding a fusion protein linking murine ubiquitin (UB) to the N-terminus of the full-length mTRP-2" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004444 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3731" ; obo:VO_0001818 "3731" ; a owl:Class ; rdfs:label "Neuroblastoma DNA vaccine HuDsec" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_769 ] . obo:VO_0004445 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3736" ; obo:VO_0001818 "3736" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine pcDNA3-STEAP encoding six-transmembrane epithelial antigen" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0004446 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3737" ; obo:VO_0001818 "3737" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine hPSMAt encoding PSMA" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0004447 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3738" ; obo:VO_0001818 "3738" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine rPSMAt encoding PSMA" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0004448 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3740" ; obo:VO_0001818 "3740" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine pVax-PSA" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0004449 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3742" ; obo:VO_0001818 "3742" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine psig-3P-Fc encoding 3P(hPSM, hPAP, or hPSA)-Fc fusion protein" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0004450 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3744" ; obo:VO_0001818 "3744" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine PSCA-HSP encoding PSCA and HSP" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0004451 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3745" ; obo:VO_0001818 "3745" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine encoding PSCA" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0004452 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3746" ; obo:VO_0001818 "3746" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine pmPSCA encoding PSCA" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0004453 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine pMIC3i encoding the complete MIC3-ORF (RH(ERP) strain)" ; rdfs:seeAlso "violinID: 3754" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004454 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine pVR1020-GRA1" ; rdfs:seeAlso "violinID: 3755" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004455 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine T.g.HSP70" ; rdfs:seeAlso "violinID: 3756" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004456 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chinese S. japonicum DNA vaccine pCMV-Sjc97 encoding paramyosin" ; rdfs:seeAlso "violinID: 3757" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004457 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chinese S. japonicum DNA vaccine pVAX/SjFABP encoding FABP" ; rdfs:seeAlso "violinID: 3758" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004458 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chinese S. japonicum DNA vaccine SjCTPI" ; rdfs:seeAlso "violinID: 3760" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004459 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chinese S. japonicum DNA vaccine SjCTPI-Hsp70" ; rdfs:seeAlso "violinID: 3761" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004460 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chinese S. japonicum DNA vaccine pVIVO2-IL12-Sj23 encoding Sj23 and IL-12" ; rdfs:seeAlso "violinID: 3762" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004461 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. mansoni DNA vaccine Sm23-pcDNA encoding Sm23" ; rdfs:seeAlso "violinID: 3763" ; rdfs:subClassOf obo:VO_0001033, obo:VO_0003046, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6183 ] . obo:VO_0004462 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. mansoni DNA vaccine pcDNA/CTSOD encoding SOD" ; rdfs:seeAlso "violinID: 3764" ; rdfs:subClassOf obo:VO_0001033, obo:VO_0003046, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6183 ] . obo:VO_0004463 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. mansoni DNA vaccine pcDNA/GPXbb encoding glutathione-S-peroxidase, GPX" ; rdfs:seeAlso "violinID: 3765" ; rdfs:subClassOf obo:VO_0001033, obo:VO_0003046, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6183 ] . obo:VO_0004464 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. mansoni DNA vaccine Sm-p80-pcDNA3 encoding the large subunit of S. mansoni calpain" ; rdfs:seeAlso "violinID: 3767" ; rdfs:subClassOf obo:VO_0001033, obo:VO_0003046, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6183 ] . obo:VO_0004465 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3768" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/520" ; obo:OGG_0000000006 "7299" ; obo:VO_0001818 "3768" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase" ; rdfs:label "Melanoma DNA vaccine xenogeneic DNA encoding murine tyrosinase" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004466 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine sA encoding prM and E from Dengue Virus 4" ; rdfs:seeAlso "violinID: 3770" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004467 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine sB encoding E" ; rdfs:seeAlso "violinID: 3771" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004468 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine sC encoding prM and E" ; rdfs:seeAlso "violinID: 3772" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004469 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine sABC encoding prM and E" ; rdfs:seeAlso "violinID: 3773" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004470 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine D1ME encoding prM and E" ; rdfs:seeAlso "violinID: 3778" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004471 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine pE1D2 encoding E from Dengue Virus 2 strain New Guinea C" ; rdfs:seeAlso "violinID: 3779" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004472 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine pcTPANS1 encoding NS1 fused to the tissue plasminogen activator signal sequence" ; rdfs:seeAlso "violinID: 3781" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004473 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine 1040D2MEL encoding dengue-2 prM-E-LAMP chimeric protein" ; rdfs:seeAlso "violinID: 3783" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004474 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue virus DNA vaccine p1012D2ME encoding prM and E from DEN 2 New Guinea C strain" ; rdfs:seeAlso "violinID: 3784" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004475 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus DNA vaccine hCRTE6E7L2 DNA encoding CRT linked to E6, E7 and L2" ; rdfs:seeAlso "violinID: 3785" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0004476 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine pTPA-PA63" ; rdfs:seeAlso "violinID: 3792" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004477 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine pLAMP1-PA63" ; rdfs:seeAlso "violinID: 3793" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004478 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine pTPA-P" ; rdfs:seeAlso "violinID: 3795" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004479 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine pIMS-120 encoding PA" ; rdfs:seeAlso "violinID: 3796" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004480 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine pCPA" ; rdfs:seeAlso "violinID: 3801" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004481 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA vaccine PA83 furin" ; rdfs:seeAlso "violinID: 3802" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004482 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaccinia virus DNA vaccine A33R from strain IHD-J" ; rdfs:seeAlso "violinID: 3805" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10245 ] . obo:VO_0004483 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaccinia virus DNA vaccine B5R" ; rdfs:seeAlso "violinID: 3808" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10245 ] . obo:VO_0004484 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaccinia virus DNA vaccine pWRG/L1R" ; rdfs:seeAlso "violinID: 3810" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10245 ] . obo:VO_0004485 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaccinia virus DNA vaccine 4pox" ; rdfs:seeAlso "violinID: 3814" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10245 ] . obo:VO_0004486 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaccinia virus DNA vaccine wtD8L" ; rdfs:seeAlso "violinID: 3815" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10245 ] . obo:VO_0004487 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaccinia virus DNA vaccine tPA-D8L" ; rdfs:seeAlso "violinID: 3816" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10245 ] . obo:VO_0004488 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VEE virus DNA vaccine encoding 26S" ; rdfs:seeAlso "violinID: 3822" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004489 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "WEE virus DNA vaccine pVHX-6 encoding 26S" ; rdfs:seeAlso "violinID: 3823" ; rdfs:subClassOf obo:VO_0012188, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11039 ] . obo:VO_0004490 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VEE virus DNA vaccine pSTU-TRDF encoding VEEV E3-E2-6K" ; rdfs:seeAlso "violinID: 3829" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0004491 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Sindbis virus DNA vaccine encoding E2" ; rdfs:seeAlso "violinID: 3830" ; rdfs:subClassOf obo:VO_0003043, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11034 ] . obo:VO_0004492 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FeLV DNA vaccine gag/pol and env" ; rdfs:seeAlso "violinID: 3831" ; rdfs:subClassOf obo:VO_0000843, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11768 ] . obo:VO_0004493 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IPNV DNA vaccine pEGFP-N1-SegA and pEGFP-N1-VP2" ; rdfs:seeAlso "violinID: 3834" ; rdfs:subClassOf obo:VO_0003055, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11002 ] . obo:VO_0004494 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VHSV DNA vaccine pVHS-G encoding glycoproteins" ; rdfs:seeAlso "violinID: 3836" ; rdfs:subClassOf obo:VO_0001224, obo:VO_0003056, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11287 ] . obo:VO_0004495 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IHNV DNA vaccine pIHN-G encoding glycoproteins" ; rdfs:seeAlso "violinID: 3837" ; rdfs:subClassOf obo:VO_0012165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11290 ] . obo:VO_0004496 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. marinum pCMV-85A" ; rdfs:seeAlso "violinID: 3838" ; rdfs:subClassOf obo:VO_0003058, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1781 ] . obo:VO_0004497 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian influenza virus DNA vaccine pH5HA" ; rdfs:seeAlso "violinID: 3839" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004498 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian influenza virus DNA vaccine pN1NA encoding N1 neuraminidase" ; rdfs:seeAlso "violinID: 3840" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004499 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian influenza virus DNA vaccine pNP" ; rdfs:seeAlso "violinID: 3841" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004500 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pCMVH5HA" ; rdfs:seeAlso "violinID: 3842" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004501 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine p-Beta-actinH7HA" ; rdfs:seeAlso "violinID: 3844" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004502 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pCAGGoptiHA" ; rdfs:seeAlso "violinID: 3845" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004503 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine pCAGGHA" ; rdfs:seeAlso "violinID: 3846" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004504 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian influenza DNA vaccine pCMV-M" ; rdfs:seeAlso "violinID: 3847" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004505 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian influenza virus DNA vaccine pCMV-HA" ; rdfs:seeAlso "violinID: 3848" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004506 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PRRSV DNA vaccine pCA-U-optiGP5" ; rdfs:seeAlso "violinID: 3849" ; rdfs:subClassOf obo:VO_0001802, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0004507 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PRRSV DNA vaccine pIRESorf5/IFN-Gamma" ; rdfs:seeAlso "violinID: 3852" ; rdfs:subClassOf obo:VO_0001802, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0004508 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PRRSV DNA vaccine pIRESorf5/IL-2" ; rdfs:seeAlso "violinID: 3853" ; rdfs:subClassOf obo:VO_0001802, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0004509 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PRRSV DNA vaccine pIRESorf7/IL-2" ; rdfs:seeAlso "violinID: 3854" ; rdfs:subClassOf obo:VO_0001802, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0004510 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PRRSV DNA vaccine pCI-ORF5/ORF6" ; rdfs:seeAlso "violinID: 3857" ; rdfs:subClassOf obo:VO_0001802, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28344 ] . obo:VO_0004511 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chinese S. japonicum DNA vaccine SjC23-Hsp70" ; rdfs:seeAlso "violinID: 3860" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004512 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chinese S. japonicum DNA vaccine SjC23" ; rdfs:seeAlso "violinID: 3861" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004513 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. burgdorferi DNA vaccine encoding strain B31 OspA" ; rdfs:seeAlso "violinID: 3863" ; rdfs:subClassOf obo:VO_0000764, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_139 ] . obo:VO_0004514 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA vaccine expressing the E2 protein" ; rdfs:seeAlso "violinID: 3864" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11096 ] . obo:VO_0004515 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pCgap DNA vaccine encoding glyceraldehyde-3-phosphate dehydrogenase" ; rdfs:seeAlso "violinID: 3865" ; rdfs:subClassOf obo:VO_0000611, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_738 ] . obo:VO_0004516 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DNA vaccine expressing PspA" ; rdfs:seeAlso "violinID: 3867" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004517 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PsaA DNA Vaccine" ; rdfs:seeAlso "violinID: 3868" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004518 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3869" ; obo:VO_0001818 "3869" ; a owl:Class ; rdfs:label "B16 melanoma DNA vaccine pSin-mTRP-1" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004519 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes Simplex Virus Type 1 DNA Vaccine pRSC-gD-IL-21" ; rdfs:seeAlso "violinID: 3870" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004520 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes Simplex Virus Type 1 DNA Vaccine encoding 5gP" ; rdfs:seeAlso "violinID: 3871" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004521 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes Simplex Virus 2 DNA Vaccine Vaxfectin-gD2" ; rdfs:seeAlso "violinID: 3872" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004522 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes Simplex Virus 2 DNA Vaccine encoding gD" ; rdfs:seeAlso "violinID: 3873" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004523 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes Simplex Virus 2 DNA Vaccine encoding gD with CD40L" ; rdfs:seeAlso "violinID: 3874" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004524 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Classical Swine Fever Virus DNA Vaccine pcDNA/E2 with TRIF" ; rdfs:seeAlso "violinID: 3876" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11096 ] . obo:VO_0004525 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Avian pneumovirus DNA Vaccine expressing the F gene" ; rdfs:seeAlso "violinID: 3878" ; rdfs:subClassOf obo:VO_0001514, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_38525 ] . obo:VO_0004526 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Murine cytomegalovirus DNA vaccine pgM-pgN" ; rdfs:seeAlso "violinID: 3880" ; rdfs:subClassOf obo:VO_0003062, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10366 ] . obo:VO_0004527 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. maxima DNA vaccine pcDNA-Gam56" ; rdfs:seeAlso "violinID: 3881" ; rdfs:subClassOf obo:VO_0001125, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5804 ] . obo:VO_0004528 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine pVAX-TgMIC13" ; rdfs:seeAlso "violinID: 3882" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004529 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis D DNA vaccine pcDNA3p27/Ad5F35p27" ; rdfs:seeAlso "violinID: 3883" ; rdfs:subClassOf obo:VO_0003059, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12475 ] . obo:VO_0004530 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. major DNA vaccine pcLACK + IL-22" ; rdfs:seeAlso "violinID: 3884" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004531 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine ROP8-pVAX-1" ; rdfs:seeAlso "violinID: 3885" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004532 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. cruzi DNA vaccine encoding TSA-1 and Tc24" ; rdfs:seeAlso "violinID: 3886" ; rdfs:subClassOf obo:VO_0001385, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5693 ] . obo:VO_0004533 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IBDV DNA vaccine pCAGoptiVP2/rVP2" ; rdfs:seeAlso "violinID: 3887" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004534 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IBDV DNA vaccine pCAGVP243-IL-18" ; rdfs:seeAlso "violinID: 3888" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004535 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IBV DNA vaccine pVAX1-16S1/M/N" ; rdfs:seeAlso "violinID: 3889" ; rdfs:subClassOf obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] . obo:VO_0004536 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. multocida DNA vaccine pcDNA-OMPH + pcDNA-OMPA" ; rdfs:seeAlso "violinID: 3890" ; rdfs:subClassOf obo:VO_0000620, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ] . obo:VO_0004537 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. multocida DNA vaccine pcDNA-OMPH/OMPA" ; rdfs:seeAlso "violinID: 3891" ; rdfs:subClassOf obo:VO_0000620, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_747 ] . obo:VO_0004538 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BVDV DNA vaccine encoding E2" ; rdfs:seeAlso "violinID: 3892" ; rdfs:subClassOf obo:VO_0003061, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_54315 ] . obo:VO_0004539 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. rhusiopathiae DNA vaccine pcD-ACSC" ; rdfs:seeAlso "violinID: 3893" ; rdfs:subClassOf obo:VO_0001456, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1648 ] . obo:VO_0004540 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. avium DNA vaccine DNA-Av35/p2AIL12" ; rdfs:seeAlso "violinID: 3894" ; rdfs:subClassOf obo:VO_0002501, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1764 ] . obo:VO_0004541 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. aureus DNA vaccine pClfaSrtD13" ; rdfs:seeAlso "violinID: 3895" ; rdfs:subClassOf obo:VO_0002502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0004542 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. aureus DNA vaccine encoding Efb, FnbpA, ClfA, Cna" ; rdfs:seeAlso "violinID: 3896" ; rdfs:subClassOf obo:VO_0002502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1280 ] . obo:VO_0004543 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. anthracis DNA Vaccine expressing PA" ; rdfs:seeAlso "violinID: 3897" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004544 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "A. pleuropneumoniae DNA vaccine pcDNA-apxIA/pcDNA-apxIIA" ; rdfs:seeAlso "violinID: 3898" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_715 ] . obo:VO_0004545 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pertussis DNA vaccine pcDNA/S1" ; rdfs:seeAlso "violinID: 3899" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] . obo:VO_0004546 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. abortus DNA vaccine pVF278" ; rdfs:seeAlso "violinID: 3900" ; rdfs:subClassOf obo:VO_0000108, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_234 ] . obo:VO_0004547 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue Virus DNA Vaccine expressing prM/E proteins" ; rdfs:seeAlso "violinID: 3902" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004548 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue Virus DNA Vaccine D1ME-VRP" ; rdfs:seeAlso "violinID: 3903" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004549 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue Virus DNA Vaccine encoding NS1" ; rdfs:seeAlso "violinID: 3904" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004550 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Feline immunodeficiency virus recombinant vector vaccine FIV-Delta-RT" ; rdfs:seeAlso "violinID: 3906" ; rdfs:subClassOf obo:VO_0001508, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11673 ] . obo:VO_0004551 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Foot-and-Mouth Disease Virus DNA Vaccine pSinCMV-Vac-MEG990" ; rdfs:seeAlso "violinID: 3907" ; rdfs:subClassOf obo:VO_0001213, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12110 ] . obo:VO_0004552 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Foot-and-Mouth Disease Virus Cationic Microparticle-coated DNA Vaccine" ; rdfs:seeAlso "violinID: 3908" ; rdfs:subClassOf obo:VO_0001213, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12110 ] . obo:VO_0004553 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FMDV DNA Vaccine encoding P1 and non-structural proteins 2A, 3C, and 3D" ; rdfs:seeAlso "violinID: 3909" ; rdfs:subClassOf obo:VO_0001213, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12110 ] . obo:VO_0004554 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. trachomatis DNA vaccine pWRG7079::MOMP" ; rdfs:seeAlso "violinID: 3910" ; rdfs:subClassOf obo:VO_0001207, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_813 ] . obo:VO_0004555 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. pneumoniae DNA vaccine pHSP-60" ; rdfs:seeAlso "violinID: 3911" ; rdfs:subClassOf obo:VO_0012173, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83558 ] . obo:VO_0004556 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tarda DNA vaccine pCE18" ; rdfs:seeAlso "violinID: 3912" ; rdfs:subClassOf obo:VO_0002506, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_636 ] . obo:VO_0004557 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tarda DNA vaccine pCE6" ; rdfs:seeAlso "violinID: 3913" ; rdfs:subClassOf obo:VO_0002506, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_636 ] . obo:VO_0004558 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tarda DNA vaccine pCEsa1" ; rdfs:seeAlso "violinID: 3914" ; rdfs:subClassOf obo:VO_0002506, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_636 ] . obo:VO_0004559 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori DNA vaccine poipA" ; rdfs:seeAlso "violinID: 3915" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0004560 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori DNA vaccine pcDNA3.1-hspA" ; rdfs:seeAlso "violinID: 3916" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0004561 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori DNA vaccine pcDNA3.1-hspB" ; rdfs:seeAlso "violinID: 3917" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0004562 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leptospira interrogans DNA vaccine ompL1-pcDNA3.1(+)" ; rdfs:seeAlso "violinID: 3918" ; rdfs:subClassOf obo:VO_0000391, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0004563 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leptospira interrogans DNA vaccine pTARGET/ LigBrep" ; rdfs:seeAlso "violinID: 3919" ; rdfs:subClassOf obo:VO_0000391, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_171 ] . obo:VO_0004564 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SIV recombinant vector vaccine rAd5/rLCMV" ; rdfs:seeAlso "violinID: 3920" ; rdfs:subClassOf obo:VO_0000751, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11723 ] . obo:VO_0004565 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Laryngotracheitis DNA Vaccine encoding gB" ; rdfs:seeAlso "violinID: 3921" ; rdfs:subClassOf obo:VO_0001488, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0004566 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg virus recombinant vector vaccine MBGV GP/MBGV NP" ; rdfs:seeAlso "violinID: 3922" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004567 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. rhabdovirus DNA Vaccine encoding N and G" ; rdfs:seeAlso "violinID: 3923" ; rdfs:subClassOf obo:VO_0002455, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980915 ] . obo:VO_0004568 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine M2-DNA/M2-Ad" ; rdfs:seeAlso "violinID: 3924" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004569 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. meningitidis DNA vaccine P3A" ; rdfs:seeAlso "violinID: 3926" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0004570 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. aeruginosa DNA vaccine pGACAG-OprF/OprI" ; rdfs:seeAlso "violinID: 3927" ; rdfs:subClassOf obo:VO_0000393, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0004571 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. aeruginosa DNA vaccine pGACAG-PcrV" ; rdfs:seeAlso "violinID: 3928" ; rdfs:subClassOf obo:VO_0000393, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0004572 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. aeruginosa DNA vaccine pGACAG-OprF/OprI + pGACAG-PcrV + pGACAG-PilA" ; rdfs:seeAlso "violinID: 3929" ; rdfs:subClassOf obo:VO_0000393, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0004573 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Y. pestis DNA vaccine YscF-2" ; rdfs:seeAlso "violinID: 3930" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004574 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BRSV DNA vaccine VCL-Fb" ; rdfs:seeAlso "violinID: 3931" ; rdfs:subClassOf obo:VO_0001507, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11246 ] . obo:VO_0004575 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Duck hepatitis virus 1 DNA vaccine pSCA/VP1" ; rdfs:seeAlso "violinID: 3932" ; rdfs:subClassOf obo:VO_0001528, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_691956 ] . obo:VO_0004576 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hantavirus DNA vaccine pWRG/HTN-M" ; rdfs:seeAlso "violinID: 3933" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980442 ] . obo:VO_0004577 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RHDV DNA vaccine pcDNA-VP60" ; rdfs:seeAlso "violinID: 3934" ; rdfs:subClassOf obo:VO_0001382, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11976 ] . obo:VO_0004578 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HSV 2 DNA vaccine pVAX-HSV-2gD-HSP70" ; rdfs:seeAlso "violinID: 3935" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004579 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HRSV DNA vaccine DRF-412" ; rdfs:seeAlso "violinID: 3936" ; rdfs:subClassOf obo:VO_0002512, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11250 ] . obo:VO_0004580 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HRSV DNA vaccine pND-G" ; rdfs:seeAlso "violinID: 3937" ; rdfs:subClassOf obo:VO_0002512, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11250 ] . obo:VO_0004581 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IBV DNA vaccine pVAX1-N" ; rdfs:seeAlso "violinID: 3938" ; rdfs:subClassOf obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] . obo:VO_0004582 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IBV DNA vaccine pVAX-S1 with GM-CSF adjuvant" ; rdfs:seeAlso "violinID: 3939" ; rdfs:subClassOf obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] . obo:VO_0004583 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. rhabdovirus DNA Vaccine encoding G" ; rdfs:seeAlso "violinID: 3940" ; rdfs:subClassOf obo:VO_0002455, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980915 ] . obo:VO_0004584 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infectious Bronchitis Virus DNA Vaccine encoding S1, N, and M" ; rdfs:seeAlso "violinID: 3941" ; rdfs:subClassOf obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] . obo:VO_0004585 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infectious Bursal Disease Virus DNA Vaccine expressing VP2" ; rdfs:seeAlso "violinID: 3942" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004586 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus DNA Vaccine P-JEV" ; rdfs:seeAlso "violinID: 3943" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11072 ] . obo:VO_0004587 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus DNA Vaccine pCJ-3/E encoding E" ; rdfs:seeAlso "violinID: 3944" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11072 ] . obo:VO_0004588 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "REV DNA vaccine VP22/gag and VP22/env" ; rdfs:seeAlso "violinID: 3946" ; rdfs:subClassOf obo:VO_0002544, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11636 ] . obo:VO_0004589 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. yoelii DNA vaccine pDIP/PyCSP. 1" ; rdfs:seeAlso "violinID: 3947" ; rdfs:subClassOf obo:VO_0002514, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004590 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. yoelii DNA vaccine encoding PySSP2" ; rdfs:seeAlso "violinID: 3948" ; rdfs:subClassOf obo:VO_0002514, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004591 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. berghei DNA vaccine encoding PbCSP" ; rdfs:seeAlso "violinID: 3949" ; rdfs:subClassOf obo:VO_0002513, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004592 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. yoelii DNA vaccine pPyHsp60-VR1012" ; rdfs:seeAlso "violinID: 3950" ; rdfs:subClassOf obo:VO_0002514, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004593 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. yoelii DNA vaccine encoding MSP1" ; rdfs:seeAlso "violinID: 3951" ; rdfs:subClassOf obo:VO_0002514, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004594 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. berghei DNA vaccine CSP-3p28" ; rdfs:seeAlso "violinID: 3952" ; rdfs:subClassOf obo:VO_0002513, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004595 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. knowlesi DNA vaccine encoding PkCSP, PkSSP2, PkAMA1, and PkMSP1p42" ; rdfs:seeAlso "violinID: 3953" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004596 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SHIV DNA vaccine encoding env and gag" ; rdfs:seeAlso "violinID: 3954" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004597 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SHIV(Ba-L) DNA vaccine encoding env and gag" ; rdfs:seeAlso "violinID: 3955" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004598 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GSK1437173A" ; rdfs:seeAlso "violinID: 3956" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004599 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human cytomegalovirus DNA vaccine pcGB" ; rdfs:seeAlso "violinID: 3958" ; rdfs:subClassOf obo:VO_0001227, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10359 ] . obo:VO_0004600 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCG-SIVgag and rDIsSIVgag Prime-boost SHIV vaccine" ; rdfs:seeAlso "violinID: 3960" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004601 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. pneumoniae pspA-rBCG Vector Vaccine" ; rdfs:seeAlso "violinID: 3961" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0004602 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii recombinant vaccine vector rBCGpMV361-TgCyP" ; rdfs:seeAlso "violinID: 3962" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004603 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AE-Poxine" ; rdfs:seeAlso "violinID: 3963" ; rdfs:subClassOf obo:VO_0001522, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_70796 ] . obo:VO_0004604 obo:IAO_0000115 "A dendritic cell vaccine consisting of dendritic cells (DCs) electroporated with mRNA encoding three adjuvants, CD40 ligand (CD40L), a constitutively active TLR4, and CD70 (all together termed TriMix); coelectroporated with full-length mRNA encoding MAGE-A3, MAGE-C2, Tyrosinase and gp100; and linked to DC-LAMP, with potential immunostimulating activity. Upon vaccination, the DCs may stimulate the immune system to mount an antigen-specific cytotoxic T-lymphocyte (CTL) response against the melanoma antigens. This may decrease cellular proliferation of melanoma cells expressing these antigens. Electroporation with the adjuvants CD40L and TLR4 allows for the generation of mature and active DCs; electroporation with CD70 provides a costimulatory signal to CD27+ naive T cells thereby supporting T-cell proliferation and inhibiting T-cell apoptosis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5238" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/286" ; obo:OGG_0000000006 "4102", "51438", "6490", "7099", "7299", "959", "970" ; obo:VO_0001818 "5238" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)|Gene name: MAGEA3|Gene name: MAGEC2|Gene name: CD40LG|Gene name: Tyrosinase|Gene name: TLR4|Gene name: CD70" ; rdfs:label "Autologous TriMix-DC Melanoma Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004605 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SL3261 expressing T. spiralis Ag30" ; rdfs:seeAlso "violinID: 3969" ; rdfs:subClassOf obo:VO_0001074, obo:VO_0002792 . obo:VO_0004606 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Aeromonas hydrophila LSA34 vector vaccine WED/pUTDgap" ; rdfs:seeAlso "violinID: 3970" ; rdfs:subClassOf obo:VO_0002505, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_644 ] . obo:VO_0004607 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Actinobacillus pleuropneumoniae HS93Tox-/pIG-T1K vectored vaccine" ; rdfs:seeAlso "violinID: 3972" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_715 ] . obo:VO_0004608 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bordetella pertussis BPZE vectored vaccine" ; rdfs:seeAlso "violinID: 3973" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] . obo:VO_0004609 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3987" ; obo:VO_0001818 "3987" ; a owl:Class ; rdfs:label "pCR3.1-VS-HSP65-TP-GRP6-M2" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004610 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4001" ; obo:VO_0001818 "4001" ; a owl:Class ; rdfs:label "SRL172" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004611 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4019" ; obo:VO_0001818 "4019" ; a owl:Class ; rdfs:label "VMCL" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004612 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4025" ; obo:VO_0001818 "4025" ; a owl:Class ; rdfs:label "Newcastle disease virus lysate" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004613 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4044" ; obo:VO_0001818 "4044" ; a owl:Class ; rdfs:label "smallpox vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004614 obo:IAO_0000117 "NF", "Oliver He", "RS", "Yuying Pan" ; obo:IAO_0000119 "PubMed:22896657", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4054" ; obo:VO_0001818 "4054" ; a owl:Class ; rdfs:label "mRNA-electroporated dendritic cells encoding gp100 and tyrosinase as melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004615 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4057" ; obo:VO_0001818 "4057" ; a owl:Class ; rdfs:label "pcDNA3-MCC/ST" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004616 obo:IAO_0000115 "The approach focuses on the use of five primary patient derived melanoma cells (MEL-2, MEL-V, 3MM, KFM, and GLM-2). These cells display differential in vitro migratory and invasive properties as well as have the ability to form solid tumors when implanted into BALB/c nude mice. The retention of the innate phenotype of these primary patient derived cells together with the expression of a multitude repertoire of melanoma associated antigens offers a novel opportunity to target melanoma so as to avoid immune evasion" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4064" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/557" ; obo:OGG_0000000006 "2315", "6490" ; obo:VO_0001818 "4064" ; a owl:Class ; rdfs:comment "Gene name: MLANA|Gene name: gp100" ; rdfs:label "Multivalent immunotherapeutic vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004617 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4079" ; obo:VO_0001818 "4079" ; a owl:Class ; rdfs:label "short overlapping peptides and full-length recombinant protein" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004618 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BCG-DHTM" ; rdfs:seeAlso "violinID: 4082" ; rdfs:subClassOf obo:VO_0003130 . obo:VO_0004619 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rSPV-PCV2-cap" ; rdfs:seeAlso "violinID: 4083" ; rdfs:subClassOf obo:VO_0001524, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_85708 ] . obo:VO_0004620 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vFP89-H5" ; rdfs:seeAlso "violinID: 4084" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004621 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vNDV-H5" ; rdfs:seeAlso "violinID: 4085" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004622 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "fp-IBD1" ; rdfs:seeAlso "violinID: 4087" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004623 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rDEV-re6 (H5)" ; rdfs:seeAlso "violinID: 4088" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004624 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FPV-LT vaccine" ; rdfs:seeAlso "violinID: 4089" ; rdfs:subClassOf obo:VO_0000609, obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0004625 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rFPV-IBDV-VP2" ; rdfs:seeAlso "violinID: 4091" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004626 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LT-BCG- Ag85B /Rv3425" ; rdfs:seeAlso "violinID: 4092" ; rdfs:subClassOf obo:VO_0003130 . obo:VO_0004627 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. T -PpSP15" ; rdfs:seeAlso "violinID: 4095" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004628 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "A2-CPA-CPB(-CTE)-recombinant L. tarentolae" ; rdfs:seeAlso "violinID: 4096" ; rdfs:subClassOf obo:VO_0012159, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5671 ] . obo:VO_0004629 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. T -HIV-1 Gag" ; rdfs:seeAlso "violinID: 4097" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004630 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AdC68- rabies virus glycoprotein" ; rdfs:seeAlso "violinID: 4099" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004631 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rAd-GP (Ebola virus)" ; rdfs:seeAlso "violinID: 4100" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004632 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HVT-ND" ; rdfs:seeAlso "violinID: 4102" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560319 ] . obo:VO_0004633 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rHVT-H5" ; rdfs:seeAlso "violinID: 4103" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004634 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rHVT-H5 (clade 2.2 H5N1 HPAIV)" ; rdfs:seeAlso "violinID: 4104" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004635 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rSPV-MRP (Streptococcus suis)" ; rdfs:seeAlso "violinID: 4106" ; rdfs:subClassOf obo:VO_0002788, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1307 ] . obo:VO_0004636 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rSPV-HA1 (Swine influenza virus H1N1)" ; rdfs:seeAlso "violinID: 4107" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004637 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HS93Tox-/pIG-T1K" ; rdfs:seeAlso "violinID: 4108" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_715 ] . obo:VO_0004638 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-SIV/gp120" ; rdfs:seeAlso "violinID: 4110" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004639 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-rabies" ; rdfs:seeAlso "violinID: 4111" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004640 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli-CPPs (Edwardsiella tarda)" ; rdfs:seeAlso "violinID: 4112" ; rdfs:subClassOf obo:VO_0002506, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_636 ] . obo:VO_0004641 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CAdVax-ZEBOV/SEBOV" ; rdfs:seeAlso "violinID: 4113" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004642 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CAdVax-RVFV glycoprotein" ; rdfs:seeAlso "violinID: 4114" ; rdfs:subClassOf obo:VO_0012166, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11588 ] . obo:VO_0004643 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CAdVax-Den12/Den34" ; rdfs:seeAlso "violinID: 4115" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0004644 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CAdVax-Filoviruses (Ebola )" ; rdfs:seeAlso "violinID: 4116" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004645 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CAdVa-Filoviruses (EbMarburg viruses)" ; rdfs:seeAlso "violinID: 4117" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004646 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cAdVaxM(fus)" ; rdfs:seeAlso "violinID: 4118" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0004647 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cAdVax-based bivalent ebola virus vaccine (Sudan and Zaire species)" ; rdfs:seeAlso "violinID: 4119" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004648 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RB51-SRS2" ; rdfs:seeAlso "violinID: 4120" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] . obo:VO_0004649 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RB51--MIC3/GRA6/MIC1/SRS2" ; rdfs:seeAlso "violinID: 4121" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] . obo:VO_0004650 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BPZE1- FHA (H1N1/PR8 influenza A virus)" ; rdfs:seeAlso "violinID: 4122" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004651 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BV-RVG/RVG" ; rdfs:seeAlso "violinID: 4124" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004652 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BV-Dual-S1" ; rdfs:seeAlso "violinID: 4125" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004653 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AcHERV-sH1N1-HA" ; rdfs:seeAlso "violinID: 4126" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004654 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BV-H5/H7/H9" ; rdfs:seeAlso "violinID: 4128" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004655 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BacMam-sHAPQ" ; rdfs:seeAlso "violinID: 4129" ; rdfs:subClassOf obo:VO_0001211, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10497 ] . obo:VO_0004656 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCGpMV361-TgCyP" ; rdfs:seeAlso "violinID: 4130" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5811 ] . obo:VO_0004657 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCG -Stx2B (Escherichia coli )" ; rdfs:seeAlso "violinID: 4131" ; rdfs:subClassOf obo:VO_0000041, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83334 ] . obo:VO_0004658 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rDEV-us78HA" ; rdfs:seeAlso "violinID: 4136" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004659 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VSV-DeltaG-H5 (H5N1)" ; rdfs:seeAlso "violinID: 4137" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004660 obo:IAO_0000115 "An Ebola virus vaccine that uses a recombinant vesicular stomatitis virus (rVSV) vector expressing an Ebola filovirus glycoprotein" ; obo:IAO_0000117 "Oliver He, Kallan Roan" ; obo:IAO_0000119 "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4140" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rVSV-EBOV" ; rdfs:seeAlso "violinID: 4140" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004661 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rVSV- SEBOV-GP and -VP40" ; rdfs:seeAlso "violinID: 4141" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004662 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rVSVDeltaG-ANDV-GPC" ; rdfs:seeAlso "violinID: 4142" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980442 ] . obo:VO_0004663 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMVA-GnGc (Rift Valley fever virus)" ; rdfs:seeAlso "violinID: 4143" ; rdfs:subClassOf obo:VO_0012166, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11588 ] . obo:VO_0004664 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMVA-SIV-CD40L Simian immunodeficiency virus vaccine" ; rdfs:seeAlso "violinID: 4144" ; rdfs:subClassOf obo:VO_0000751, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11723 ] . obo:VO_0004665 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMVA-CCHF" ; rdfs:seeAlso "violinID: 4145" ; rdfs:subClassOf obo:VO_0001365, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052518 ] . obo:VO_0004666 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA-CHIKV" ; rdfs:seeAlso "violinID: 4146" ; rdfs:subClassOf obo:VO_0002785, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_37124 ] . obo:VO_0004667 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVTT-HA-QH" ; rdfs:seeAlso "violinID: 4149" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004668 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. gordonii -M6-Sj-F1" ; rdfs:seeAlso "violinID: 4150" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004669 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Streptococcus gordonii-TTFC" ; rdfs:seeAlso "violinID: 4151" ; rdfs:subClassOf obo:VO_0000640, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] . obo:VO_0004670 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. gordonii-PT" ; rdfs:seeAlso "violinID: 4152" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] . obo:VO_0004671 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SL3261-L. major" ; rdfs:seeAlso "violinID: 4153" ; rdfs:subClassOf obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5664 ] . obo:VO_0004672 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SL3261-L. donovani" ; rdfs:seeAlso "violinID: 4154" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5661 ] . obo:VO_0004674 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SL3261-P. aeruginosa serogroup O11 O antigen" ; rdfs:seeAlso "violinID: 4156" ; rdfs:subClassOf obo:VO_0000393, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_287 ] . obo:VO_0004675 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SL3261- UreA and UreB" ; rdfs:seeAlso "violinID: 4157" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0004676 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SL3261 expressing streptococcal M protein" ; rdfs:seeAlso "violinID: 4158" ; rdfs:subClassOf obo:VO_0002852, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1314 ] . obo:VO_0004677 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Schmidt-Ruppin Rous sarcoma virus-H7 (H7N7)" ; rdfs:seeAlso "violinID: 4159" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004678 obo:IAO_0000117 "RS, NF, YH" ; obo:IAO_0000119 "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4160", "https://pubmed.ncbi.nlm.nih.gov/18708674/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RBD-rAAV-SARS-CoV" ; rdfs:seeAlso "violinID: 4160" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0004679 obo:IAO_0000117 "RS, NF, YH" ; obo:IAO_0000119 "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4161", "https://pubmed.ncbi.nlm.nih.gov/18289745/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RBD-rAAV-SARS-CoV prime/RBD-specific T cell peptide boost" ; rdfs:seeAlso "violinID: 4161" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0004680 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rNDV-ILTV-gD" ; rdfs:seeAlso "violinID: 4162" ; rdfs:subClassOf obo:VO_0000609, obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0004681 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rNDV-H5" ; rdfs:seeAlso "violinID: 4163" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004682 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rNDV-H5 ( HPAI H5N1 challenge in mule ducks)" ; rdfs:seeAlso "violinID: 4164" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004683 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rNDV-H6" ; rdfs:seeAlso "violinID: 4165" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004684 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rAPMV3-F (newcastle disease)" ; rdfs:seeAlso "violinID: 4167" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560319 ] . obo:VO_0004685 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BoHV-4-A-gD(cp)gD(106)DeltaTK" ; rdfs:seeAlso "violinID: 4168" ; rdfs:subClassOf obo:VO_0001366, obo:VO_0001484, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_39944 ] . obo:VO_0004686 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BoHV-4-A-IgK-VP2gD" ; rdfs:seeAlso "violinID: 4169" ; rdfs:subClassOf obo:VO_0001515, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40051 ] . obo:VO_0004687 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HSVT[VP7/6/2]" ; rdfs:seeAlso "violinID: 4172" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] . obo:VO_0004688 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. S- H. pylori -opm26" ; rdfs:seeAlso "violinID: 4173" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0004689 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M.S-Delta-esx-3-IKEPLUS (M. tuberculosis)" ; rdfs:seeAlso "violinID: 4174" ; rdfs:subClassOf obo:VO_0000077 . obo:VO_0004690 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "YF17D- HIV-1 p24" ; rdfs:seeAlso "violinID: 4175" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004691 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RCN-HA (H5N1)" ; rdfs:seeAlso "violinID: 4176" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004692 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RCN-F1-V (Yersinia pestis F1 and V)" ; rdfs:seeAlso "violinID: 4177" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004693 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RCN-rabies-G" ; rdfs:seeAlso "violinID: 4178" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004694 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RCN-IRES-tPA-YpF1( Yersinia pestis)" ; rdfs:seeAlso "violinID: 4179" ; rdfs:subClassOf obo:VO_0000648, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_632 ] . obo:VO_0004695 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PAV3-HA (H5N1)" ; rdfs:seeAlso "violinID: 4180" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004696 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PAV3-HA (A/Hanoi/30408/2005 H5N1)" ; rdfs:seeAlso "violinID: 4181" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004697 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rAd-P97c" ; rdfs:seeAlso "violinID: 4182" ; rdfs:subClassOf obo:VO_0000329, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2099 ] . obo:VO_0004698 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PrV-HA (swine-origin H1N1)" ; rdfs:seeAlso "violinID: 4183" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004699 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PrV-PCV2-ORF2" ; rdfs:seeAlso "violinID: 4184" ; rdfs:subClassOf obo:VO_0001524, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_85708 ] . obo:VO_0004700 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rAdV-SFV-E2" ; rdfs:seeAlso "violinID: 4185" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11096 ] . obo:VO_0004701 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhi strain Ty21a-LPS-Shigella" ; rdfs:seeAlso "violinID: 4186" ; rdfs:subClassOf obo:VO_0000769, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_620 ] . obo:VO_0004702 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhi strain Ty21a-PA (Bacillus anthracis)" ; rdfs:seeAlso "violinID: 4187" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004703 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ty21a-O-Ps (Shigella dysenteriae )" ; rdfs:seeAlso "violinID: 4188" ; rdfs:subClassOf obo:VO_0000769, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_620 ] . obo:VO_0004704 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SabRV-SIV" ; rdfs:seeAlso "violinID: 4189" ; rdfs:subClassOf obo:VO_0000751, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11723 ] . obo:VO_0004705 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4190" ; obo:VO_0001818 "4190" ; a owl:Class ; rdfs:label "Poliovirus vector expressing model antigen H2-Kb-restricted CTL epitope" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004706 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SG33-VP2/5" ; rdfs:seeAlso "violinID: 4191" ; rdfs:subClassOf obo:VO_0001515, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40051 ] . obo:VO_0004707 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Myxoma-FCV" ; rdfs:seeAlso "violinID: 4192" ; rdfs:subClassOf obo:VO_0001509, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11978 ] . obo:VO_0004708 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4193" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/496" ; obo:OGG_0000000006 "727897" ; obo:VO_0001818 "4193" ; a owl:Class ; rdfs:comment "Gene name: MUC5B" ; rdfs:label "Maraba virus MG1 Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004709 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rvOka-HN (mumps virus)" ; rdfs:seeAlso "violinID: 4194" ; rdfs:subClassOf obo:VO_0000656, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560602 ] . obo:VO_0004710 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rOka-gD2- HSV-2" ; rdfs:seeAlso "violinID: 4195" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004711 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMV- SARS-CoV -S/Ssol" ; rdfs:seeAlso "violinID: 4196" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0004712 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMV- WNV" ; rdfs:seeAlso "violinID: 4197" ; rdfs:subClassOf obo:VO_0000752, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] . obo:VO_0004713 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4198" ; obo:VO_0001818 "4198" ; a owl:Class ; rdfs:label "rMeV- SCD" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4947 ] . obo:VO_0004714 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMV-Ed-G" ; rdfs:seeAlso "violinID: 4199" ; rdfs:subClassOf obo:VO_0012169, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052225 ] . obo:VO_0004715 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rLAG- PA-DCpep" ; rdfs:seeAlso "violinID: 4200" ; rdfs:subClassOf obo:VO_0000013, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1392 ] . obo:VO_0004716 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4201" ; obo:VO_0001818 "4201" ; a owl:Class ; rdfs:label "rMCMV-TRP2" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004717 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rCMV- EBOV" ; rdfs:seeAlso "violinID: 4202" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004718 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rCMV-TT" ; rdfs:seeAlso "violinID: 4203" ; rdfs:subClassOf obo:VO_0000640, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1485 ] . obo:VO_0004719 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVB4/p24(73(3))" ; rdfs:seeAlso "violinID: 4204" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004720 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rVCG- Chlamydia-cholera" ; rdfs:seeAlso "violinID: 4205" ; rdfs:subClassOf obo:VO_0001207, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_813 ] . obo:VO_0004721 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVD 103-HgR- REPEC" ; rdfs:seeAlso "violinID: 4206" ; rdfs:subClassOf obo:VO_0000041, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83334 ] . obo:VO_0004722 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rVCG- MOMP/HSV-2-gD" ; rdfs:seeAlso "violinID: 4207" ; rdfs:subClassOf obo:VO_0001207, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_813 ] . obo:VO_0004723 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pRP-RSV-HSV-1-gB" ; rdfs:seeAlso "violinID: 4208" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10298 ] . obo:VO_0004724 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RSV-H7" ; rdfs:seeAlso "violinID: 4209" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004725 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-AHSV" ; rdfs:seeAlso "violinID: 4210" ; rdfs:subClassOf obo:VO_0001480, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40050 ] . obo:VO_0004726 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-BTV-VP2/VP5" ; rdfs:seeAlso "violinID: 4211" ; rdfs:subClassOf obo:VO_0001515, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40051 ] . obo:VO_0004727 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-HIV-2" ; rdfs:seeAlso "violinID: 4212" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004728 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-RV" ; rdfs:seeAlso "violinID: 4213" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004729 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FP-AI-H5(H5N1)" ; rdfs:seeAlso "violinID: 4214" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004730 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-AI-H5(H5N1)" ; rdfs:seeAlso "violinID: 4215" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004731 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-WNV-prM/E" ; rdfs:seeAlso "violinID: 4216" ; rdfs:subClassOf obo:VO_0000752, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] . obo:VO_0004732 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-BTV-CP(VP2/VP5)" ; rdfs:seeAlso "violinID: 4218" ; rdfs:subClassOf obo:VO_0001515, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40051 ] . obo:VO_0004733 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-NiV-G" ; rdfs:seeAlso "violinID: 4219" ; rdfs:subClassOf obo:VO_0012169, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052225 ] . obo:VO_0004734 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-NiV-F" ; rdfs:seeAlso "violinID: 4220" ; rdfs:subClassOf obo:VO_0012169, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052225 ] . obo:VO_0004735 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-EIV (equine influenza virus H3N8)" ; rdfs:seeAlso "violinID: 4221" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004736 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-WNV-PrM/E (dogs and cats)" ; rdfs:seeAlso "violinID: 4222" ; rdfs:subClassOf obo:VO_0000752, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11082 ] . obo:VO_0004737 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-HIV-2- env/gag/pol" ; rdfs:seeAlso "violinID: 4223" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004738 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-RHDV (vCP309)" ; rdfs:seeAlso "violinID: 4224" ; rdfs:subClassOf obo:VO_0001382, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11976 ] . obo:VO_0004739 obo:IAO_0000115 "Several canarypox virus recombinants expressing human or murine p53 in wild-type or mutant form were constructed" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:12006514", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4225" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "4225" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53 (P53)" ; rdfs:label "ALVAC-P53 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004740 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-FL- env/gag" ; rdfs:seeAlso "violinID: 4226" ; rdfs:subClassOf obo:VO_0000843, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11768 ] . obo:VO_0004741 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-MV-HA/F" ; rdfs:seeAlso "violinID: 4227" ; rdfs:subClassOf obo:VO_0000654, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11234 ] . obo:VO_0004742 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FP-IBDV-VP2" ; rdfs:seeAlso "violinID: 4228" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004743 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rFPV-AI-H5A-IL6" ; rdfs:seeAlso "violinID: 4229" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004744 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rFPV-ILTV" ; rdfs:seeAlso "violinID: 4230" ; rdfs:subClassOf obo:VO_0000609, obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0004745 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vFP89-HA (H5N1 HPAI virus)" ; rdfs:seeAlso "violinID: 4231" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004746 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rFPV-H5AI-L2" ; rdfs:seeAlso "violinID: 4232" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004747 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-AI-H5" ; rdfs:seeAlso "violinID: 4233" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004748 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rPFV-CSFV-E0" ; rdfs:seeAlso "violinID: 4234" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11096 ] . obo:VO_0004749 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMDV-IBDV-VP2" ; rdfs:seeAlso "violinID: 4237" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004750 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rFPV-IBDV-VP 2.4.3" ; rdfs:seeAlso "violinID: 4239" ; rdfs:subClassOf obo:VO_0001497, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10995 ] . obo:VO_0004751 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rFPV-NDV-H/F" ; rdfs:seeAlso "violinID: 4240" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2560319 ] . obo:VO_0004752 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rFP-RPV-H/F" ; rdfs:seeAlso "violinID: 4241" ; rdfs:subClassOf obo:VO_0001455, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11241 ] . obo:VO_0004753 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ac-CMV-S1 (infectious bronchitis virus)" ; rdfs:seeAlso "violinID: 4242" ; rdfs:subClassOf obo:VO_0001502, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11120 ] . obo:VO_0004754 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BV-GD-ORF2" ; rdfs:seeAlso "violinID: 4243" ; rdfs:subClassOf obo:VO_0001524, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_85708 ] . obo:VO_0004755 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rSPV/H3-2A-H1" ; rdfs:seeAlso "violinID: 4244" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004756 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HVT-ILT(FC-126 strain)" ; rdfs:seeAlso "violinID: 4245" ; rdfs:subClassOf obo:VO_0000609, obo:VO_0001231, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0004757 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCG-Ag85A/Ag85B" ; rdfs:seeAlso "violinID: 4246" ; rdfs:subClassOf obo:VO_0003130 . obo:VO_0004758 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMVA- AHS-VP2" ; rdfs:seeAlso "violinID: 4248" ; rdfs:subClassOf obo:VO_0001480, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40050 ] . obo:VO_0004759 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMVTT-HA-QH (H5N1)" ; rdfs:seeAlso "violinID: 4249" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004760 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMVTT-SIV-gpe" ; rdfs:seeAlso "violinID: 4250" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004761 obo:IAO_0000117 "NF", "Oliver He", "RS" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4251" ; obo:VO_0001818 "4251" ; a owl:Class ; rdfs:label "rMVTT- HPV16-E6/E7" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ] . obo:VO_0004762 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rLSDV-Rabies-gP" ; rdfs:seeAlso "violinID: 4253" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004763 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rLSDV-RPV" ; rdfs:seeAlso "violinID: 4254" ; rdfs:subClassOf obo:VO_0001455, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11241 ] . obo:VO_0004764 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4255" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/527" ; obo:OGG_0000000006 "4100" ; obo:VO_0001818 "4255" ; a owl:Class ; rdfs:comment "Gene name: MAGEA1" ; rdfs:label "MG1-hDCT Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0004765 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rORFV-D1701-V-HAh5n (H5N1)" ; rdfs:seeAlso "violinID: 4256" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004766 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rORFV-RabG" ; rdfs:seeAlso "violinID: 4257" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0004767 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rORFV-RHDV-VP60" ; rdfs:seeAlso "violinID: 4258" ; rdfs:subClassOf obo:VO_0001382, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11976 ] . obo:VO_0004768 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rORFV-CSFV-E2" ; rdfs:seeAlso "violinID: 4259" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11096 ] . obo:VO_0004769 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rORFV-p40(Borna disease virus)" ; rdfs:seeAlso "violinID: 4260" ; rdfs:subClassOf obo:VO_0001483, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12455 ] . obo:VO_0004770 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rORFV-PRV-gC/gD" ; rdfs:seeAlso "violinID: 4261" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0004771 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-EHV-1- vP1014" ; rdfs:seeAlso "violinID: 4262" ; rdfs:subClassOf obo:VO_0001486, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10326 ] . obo:VO_0004772 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC- CDV-H/F" ; rdfs:seeAlso "violinID: 4263" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ] . obo:VO_0004773 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC- CDV-H/F" ; rdfs:seeAlso "violinID: 4264" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ] . obo:VO_0004774 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-HIV-1" ; rdfs:seeAlso "violinID: 4265" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004775 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-HIV-2" ; rdfs:seeAlso "violinID: 4266" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004776 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-JEV" ; rdfs:seeAlso "violinID: 4267" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11072 ] . obo:VO_0004777 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ALVAC-JEV" ; rdfs:seeAlso "violinID: 4268" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11072 ] . obo:VO_0004778 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-PRV- gII/ gp50" ; rdfs:seeAlso "violinID: 4270" ; rdfs:subClassOf obo:VO_0000750, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10345 ] . obo:VO_0004779 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-SIV" ; rdfs:seeAlso "violinID: 4271" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004780 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-JEV- prM/E/ NS1" ; rdfs:seeAlso "violinID: 4274" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11072 ] . obo:VO_0004781 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VC-TetC/Tcf" ; rdfs:seeAlso "violinID: 4275" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] . obo:VO_0004782 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rAdV-SjTPI.opt" ; rdfs:seeAlso "violinID: 4280" ; rdfs:subClassOf obo:VO_0001229, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_6182 ] . obo:VO_0004783 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rPIV5-H3 (influenza virus)" ; rdfs:seeAlso "violinID: 4282" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004784 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rVEE-HA(H1N1)" ; rdfs:seeAlso "violinID: 4288" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004785 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rS.C-APP-ApxI/ApxII" ; rdfs:seeAlso "violinID: 4289" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_715 ] . obo:VO_0004786 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rS.C-APP-ApxIIA" ; rdfs:seeAlso "violinID: 4290" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_715 ] . obo:VO_0004787 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "dVV-HA5(H5N1)" ; rdfs:seeAlso "violinID: 4293" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004788 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rCPV-BTV-Cpox" ; rdfs:seeAlso "violinID: 4295" ; rdfs:subClassOf obo:VO_0001515, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_40051 ] . obo:VO_0004789 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCG-SIVgag" ; rdfs:seeAlso "violinID: 4299" ; rdfs:subClassOf obo:VO_0000751, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11723 ] . obo:VO_0004790 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCG-S1PT" ; rdfs:seeAlso "violinID: 4300" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ] . obo:VO_0004791 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rBCGMSP1-15" ; rdfs:seeAlso "violinID: 4301" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004792 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rMVA-SIV-CD40L human immunodeficiency virus vaccine" ; rdfs:seeAlso "violinID: 4302" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12721 ] . obo:VO_0004793 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HVT-LT" ; rdfs:seeAlso "violinID: 4304" ; rdfs:subClassOf obo:VO_0001488, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10386 ] . obo:VO_0004794 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-Pf7" ; rdfs:seeAlso "violinID: 4306" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004795 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Toxminus-PLD toxoid" ; rdfs:seeAlso "violinID: 4308" ; rdfs:subClassOf obo:VO_0002789, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1719 ] . obo:VO_0004796 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA-PvTRAP" ; rdfs:seeAlso "violinID: 4309" ; rdfs:subClassOf obo:VO_0000758, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004797 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ChAd63 -PvTRAP" ; rdfs:seeAlso "violinID: 4310" ; rdfs:subClassOf obo:VO_0000758, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004798 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NILV-Py CSP" ; rdfs:seeAlso "violinID: 4311" ; rdfs:subClassOf obo:VO_0002514, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004799 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SAd-ME.TRAP" ; rdfs:seeAlso "violinID: 4312" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004800 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NYVAC-CSP (malaria)" ; rdfs:seeAlso "violinID: 4313" ; rdfs:subClassOf obo:VO_0000761, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004801 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BDES-PfCSP (baculovirus dual expression system)" ; rdfs:seeAlso "violinID: 4314" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5820 ] . obo:VO_0004802 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HDAd-sFsyn" ; rdfs:seeAlso "violinID: 4315" ; rdfs:subClassOf obo:VO_0002512, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11250 ] . obo:VO_0004803 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LM1-2-E7" ; rdfs:seeAlso "violinID: 4316" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0004804 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BL21(DE3)/pUTa-E + pET28a-FT" ; rdfs:seeAlso "violinID: 4317" ; rdfs:subClassOf obo:VO_0002506, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_636 ] . obo:VO_0004805 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rVEE-Ebola-NP" ; rdfs:seeAlso "violinID: 4318" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0004806 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. bovis DNA vaccine pCI-Ag85B" ; rdfs:seeAlso "violinID: 4319" ; rdfs:subClassOf obo:VO_0001519, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1765 ] . obo:VO_0004807 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bacillus Calmette-Guérin Danish (BCG)" ; rdfs:seeAlso "violinID: 4320" ; rdfs:subClassOf obo:VO_0001519, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1765 ] . obo:VO_0004808 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "APSV Wetvax" ; rdfs:seeAlso "violinID: 4321" ; rdfs:subClassOf obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10245 ] . obo:VO_0004809 obo:IAO_0000117 "RS, NF, YH" ; obo:IAO_0000119 "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=4322" ; obo:VO_0003099 "A/Brisbane/59/2007(H1N1), A/Brisbane/10/2007(H3N2), B/Florida/4/2006; Sanofi-Pasteur" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "2008-2009 trivalent influenza vaccine" ; rdfs:seeAlso "violinID: 4322" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004810 obo:IAO_0000115 "2010-2011 trivalent seasonal inactivated influenza vaccine 2010 consisting of Influenza A virus (A/California/7/2009(H1N1)), Influenza A virus (A/Texas/50/2012(H3N2)), Influenza B virus (B/Brisbane/60/2008)" ; obo:IAO_0000117 "RS, NF, YH, RV" ; obo:IAO_0000118 "2010-2011 trivalent seasonal inactivated influenza vaccine (A/California/7/09 (H1N1), A/Perth/16/2009 (H3N2), and B/Brisbane/60/2008)" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/25596819", "https://www.ncbi.nlm.nih.gov/pubmed/27317456" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "2011-2012 trivalent inactivated vaccine (A/California/7/09 (H1N1), A/Perth /16/2009 (H3N2), and B/Brisbane/60/2008)" ; rdfs:seeAlso "violinID: 4324" ; rdfs:subClassOf obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003479 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004898 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004811 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant Aeromonas hydrophila vaccine (Aera)" ; rdfs:seeAlso "violinID: 4325" ; rdfs:subClassOf obo:VO_0002505, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_644 ] . obo:VO_0004812 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C-KCE (vBAC-C-KCE)" ; rdfs:seeAlso "violinID: 4326" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0004813 obo:IAO_0000117 "RS, NF, YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "v2RVFH" ; rdfs:seeAlso "violinID: 4327" ; rdfs:subClassOf obo:VO_0001455, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11241 ] . obo:VO_0004814 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "Biothrax (anthrax vaccine adsorbed) 0.5 ML Injectable Suspension" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/832682" ; obo:VO_0003198 "832682" ; obo:VO_0003560 "BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 0.1 MG/ML Injectable Suspension [Biothrax]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1877319", "RXAUI: 7241001, 8235202, 8235203, 8231134", "TUI: T200" ; rdfs:label "Biothrax 0.5 ML Injectable Suspension" ; rdfs:subClassOf obo:VO_0004218, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004213 ] . obo:VO_0004815 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/805573" ; obo:VO_0003198 "805573" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364569", "RXAUI: 2861602", "TUI: T129, T121" ; rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0010738 ] . obo:VO_0004816 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/805574" ; obo:VO_0003198 "805574" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364570", "RXAUI: 2861603", "TUI: T200" ; rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 UNT/ML" ; rdfs:subClassOf obo:VO_0004815 . obo:VO_0004817 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/805577" ; obo:VO_0003198 "805577" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2364572", "RXAUI: 2861607", "TUI: T200" ; rdfs:label "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 UNT/ML [Rotarix]" ; rdfs:subClassOf obo:VO_0010738 . obo:VO_0004818 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/805579" ; obo:VO_0003198 "805579" ; obo:VO_0003560 "Rotavirus Vaccine, Live Attenuated, G1P[8] Human 89-12 strain 1000000 UNT/ML Oral Suspension [Rotarix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2343398", "RXAUI: 8728820, 8728821, 2861609", "TUI: T200" ; rdfs:label "Rotarix, Rotavirus, live attenuated (RV1) G1P[8] Oral Vaccine" ; rdfs:subClassOf obo:VO_0004819, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004816 ] . obo:VO_0004819 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1182565" ; obo:VO_0003198 "1182565" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3236400", "RXAUI: 3845652", "TUI: T200" ; rdfs:label "Rotarix Oral Liquid Product" ; rdfs:subClassOf obo:VO_0010738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004818 ] . obo:VO_0004820 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798292" ; obo:VO_0003198 "798292" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344315", "RXAUI: 2851375", "TUI: T116, T129, T121" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G4 Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000097 ] . obo:VO_0004821 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798293" ; obo:VO_0003198 "798293" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344316", "RXAUI: 2851376", "TUI: T200" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 1000000 UNT/ML" ; rdfs:subClassOf obo:VO_0004820 . obo:VO_0004822 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798294" ; obo:VO_0003198 "798294" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344317", "RXAUI: 2851377", "TUI: T116, T129, T121" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000097 ] . obo:VO_0004823 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798288" ; obo:VO_0003198 "798288" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344311", "RXAUI: 2851371", "TUI: T116, T129, T121" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G2 Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000097 ] . obo:VO_0004824 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798290" ; obo:VO_0003198 "798290" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344313", "RXAUI: 2851373", "TUI: T116, T129, T121" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G3 Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000097 ] . obo:VO_0004825 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798286" ; obo:VO_0003198 "798286" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344309", "RXAUI: 2851369", "TUI: T116, T129, T121" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000097 ] . obo:VO_0004826 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798291" ; obo:VO_0003198 "798291" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344314", "RXAUI: 2851374", "TUI: T200" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 1100000 UNT/ML" ; rdfs:subClassOf obo:VO_0004824 . obo:VO_0004827 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798287" ; obo:VO_0003198 "798287" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344310", "RXAUI: 2851370", "TUI: T200" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 1100000 UNT/ML" ; rdfs:subClassOf obo:VO_0004825 . obo:VO_0004828 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798295" ; obo:VO_0003198 "798295" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344318", "RXAUI: 2851378", "TUI: T200" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 1150000 UNT/ML" ; rdfs:subClassOf obo:VO_0004822 . obo:VO_0004829 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798289" ; obo:VO_0003198 "798289" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344312", "RXAUI: 2851372", "TUI: T200" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 1400000 UNT/ML" ; rdfs:subClassOf obo:VO_0004823 . obo:VO_0004830 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1182563" ; obo:VO_0003198 "1182563" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3236398", "RXAUI: 3845650", "TUI: T200" ; rdfs:label "RotaTeq Oral Liquid Product" ; rdfs:subClassOf obo:VO_0000097 . obo:VO_0004831 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798298" ; obo:VO_0003198 "798298" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2344321", "RXAUI: 2851381", "TUI: T200" ; rdfs:label "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 1100000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 1400000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 1100000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 1000000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 1150000 UNT/ML [RotaTeq]" ; rdfs:subClassOf obo:VO_0000097, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004821 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004826 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004827 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004828 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004829 ] . obo:VO_0004832 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798300" ; obo:VO_0003198 "798300" ; obo:VO_0003560 "Human-Bovine Reassortant Rotavirus Strain G1 Vaccine 1100000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G2 Vaccine 1400000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G3 Vaccine 1100000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain G4 Vaccine 1000000 UNT/ML / Human-Bovine Reassortant Rotavirus Strain P1A[8] Vaccine 1150000 UNT/ML Oral Suspension [RotaTeq]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1698233", "RXAUI: 8728818, 8728828, 2851383", "TUI: T200" ; rdfs:label "RotaTeq, Rotavirus, live pentavalent (RV5) Oral Vaccine" ; rdfs:subClassOf obo:VO_0004830, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004831 ] . obo:VO_0004833 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1607807" ; obo:VO_0003198 "1607807" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4018289", "RXAUI: 6839906", "TUI: T200" ; rdfs:label "Quadracel Injectable Product" ; rdfs:subClassOf obo:VO_0010736 . obo:VO_0004834 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1988804" ; obo:VO_0003198 "1988804" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4530672", "RXAUI: 9702160", "TUI: T200" ; rdfs:label "Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Quadracel]" ; rdfs:subClassOf obo:VO_0010736, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003204 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003210 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003374 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003385 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003388 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003395 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003843 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003844 ] . obo:VO_0004835 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1607808" ; obo:VO_0003198 "1607808" ; obo:VO_0003560 "0.5 ML Bordetella pertussis filamentous hemagglutinin vaccine, inactivated 0.04 MG/ML / Bordetella pertussis fimbriae 2/3 vaccine, inactivated 0.01 MG/ML / Bordetella pertussis pertactin vaccine, inactivated 0.006 MG/ML / Bordetella pertussis toxoid vaccine, inactivated 0.04 MG/ML / diphtheria toxoid vaccine, inactivated 30 UNT/ML / poliovirus vaccine inactivated, type 1 (Mahoney) 80 UNT/ML / poliovirus vaccine inactivated, type 2 (MEF-1) 16 UNT/ML / poliovirus vaccine inactivated, type 3 (Saukett) 64 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Quadracel]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4018290", "RXAUI: 7253752, 9702161", "TUI: T200" ; rdfs:label "Quadracel vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0004833, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004834 ] . obo:VO_0004836 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901509" ; obo:VO_0003198 "901509" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741588", "RXAUI: 3060734", "TUI: T129, T121" ; rdfs:label "Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001246 ] . obo:VO_0004837 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901507" ; obo:VO_0003198 "901507" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741586", "RXAUI: 3060732", "TUI: T129, T121" ; rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001246 ] . obo:VO_0004838 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901511" ; obo:VO_0003198 "901511" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741590", "RXAUI: 3060736", "TUI: T129, T121" ; rdfs:label "Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001246 ] . obo:VO_0004839 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901505" ; obo:VO_0003198 "901505" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741584", "RXAUI: 3060730", "TUI: T129, T121" ; rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0001246 ] . obo:VO_0004840 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901516" ; obo:VO_0003198 "901516" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741589", "RXAUI: 3060735", "TUI: T200" ; rdfs:label "Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML" ; rdfs:subClassOf obo:VO_0004836 . obo:VO_0004841 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901508" ; obo:VO_0003198 "901508" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741587", "RXAUI: 3060733", "TUI: T200" ; rdfs:label "Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML" ; rdfs:subClassOf obo:VO_0004837 . obo:VO_0004842 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901512" ; obo:VO_0003198 "901512" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741591", "RXAUI: 3060737", "TUI: T200" ; rdfs:label "Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML" ; rdfs:subClassOf obo:VO_0004838 . obo:VO_0004843 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901506" ; obo:VO_0003198 "901506" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741585", "RXAUI: 3060731", "TUI: T200" ; rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML" ; rdfs:subClassOf obo:VO_0004839 . obo:VO_0004844 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1184384" ; obo:VO_0003198 "1184384" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3238199", "RXAUI: 3840481", "TUI: T200" ; rdfs:label "Menveo Injectable Product" ; rdfs:subClassOf obo:VO_0001246 . obo:VO_0004845 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901516" ; obo:VO_0003198 "901516" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741595", "RXAUI: 3060741", "TUI: T200" ; rdfs:label "Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML [Menveo]" ; rdfs:subClassOf obo:VO_0001246, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004840 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004841 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004843 ] . obo:VO_0004846 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/901518" ; obo:VO_0003198 "901518" ; obo:VO_0003560 "0.5 ML Neisseria meningitidis serogroup A oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.02 MG/ML / Neisseria meningitidis serogroup C oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup W-135 oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML / Neisseria meningitidis serogroup Y oligosaccharide diphtheria CRM197 protein conjugate vaccine 0.01 MG/ML Injection [Menveo]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2741597", "RXAUI: 7253602, 7251512, 7250930", "TUI: T200" ; rdfs:label "MENVEO vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0004844, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004845 ] . obo:VO_0004847 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593139" ; obo:VO_0003198 "1593139" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3859502", "RXAUI: 6809461", "TUI: T200" ; rdfs:label "Trumenba Injectable Product" ; rdfs:subClassOf obo:VO_0003081 . obo:VO_0004848 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593137" ; obo:VO_0003198 "1593137" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3859500", "RXAUI: 6809459", "TUI: T200" ; rdfs:label "Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML / Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML [Trumenba]" ; rdfs:subClassOf obo:VO_0003081, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003367 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003369 ] . obo:VO_0004849 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593138" ; obo:VO_0003198 "1593138" ; obo:VO_0003560 "meningococcal group B vaccine Prefilled Syringe [Trumenba]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3859501", "RXAUI: 6809460", "TUI: T200" ; rdfs:label "Trumenba vaccine Prefilled Syringe" ; rdfs:subClassOf obo:VO_0004847 . obo:VO_0004850 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1593140" ; obo:VO_0003198 "1593140" ; obo:VO_0003560 "0.5 ML Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen 0.12 MG/ML / Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen 0.12 MG/ML Prefilled Syringe [Trumenba]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3859503", "RXAUI: 6809462, 6809488, 7253600, 6809470", "TUI: T200" ; rdfs:label "Trumenba vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0004849, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004848 ] . obo:VO_0004851 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601406" ; obo:VO_0003198 "1601406" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3883559", "RXAUI: 6827964", "TUI: T200" ; rdfs:label "Bexsero Injectable Product" ; rdfs:subClassOf obo:VO_0003066 . obo:VO_0004852 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601404" ; obo:VO_0003198 "1601404" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3883499", "RXAUI: 6827962", "TUI: T200" ; rdfs:label "meningococcal group B vaccine 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 0.05 MG/ML [Bexsero]" ; rdfs:subClassOf obo:VO_0003066, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003349 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003361 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003363 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003365 ] . obo:VO_0004853 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1601407" ; obo:VO_0003198 "1601407" ; obo:VO_0003560 "0.5 ML meningococcal group B vaccine 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B recombinant NHBA fusion protein antigen 0.1 MG/ML / Neisseria meningitidis serogroup B strain NZ98/254 outer membrane vesicle 0.05 MG/ML Prefilled Syringe [Bexsero]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3882668", "RXAUI: 7253601, 6827965, 6827966, 6827968, 6827967", "TUI: T200" ; rdfs:label "BEXSERO vaccine 0.5 ML Prefilled Syringe" ; rdfs:subClassOf obo:VO_0003359, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004852 ] . obo:VO_0004854 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/833079" ; obo:VO_0003198 "833079" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2608637", "RXAUI: 2944708", "TUI: T116, T121" ; rdfs:label "smallpox vaccine live vaccinia virus" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000433, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000003 ] . obo:VO_0004855 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/833080" ; obo:VO_0003198 "833080" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2608638", "RXAUI: 2944709", "TUI: T200" ; rdfs:label "smallpox vaccine live vaccinia virus 500000000 UNT/ML" ; rdfs:subClassOf obo:VO_0004854 . obo:VO_0004856 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1165898" ; obo:VO_0003198 "1165898" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3220139", "RXAUI: 3828366", "TUI: T200" ; rdfs:label "ACAM2000 Injectable Product" ; rdfs:subClassOf obo:VO_0000003 . obo:VO_0004857 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/833086" ; obo:VO_0003198 "833086" ; obo:VO_0003560 "smallpox vaccine live vaccinia virus 500000000 UNT/ML Injectable Solution [ACAM2000]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2608644", "RXAUI: 2944716, 2944715, 7252433", "TUI: T200" ; rdfs:label "ACAM2000 smallpox (vaccinia) vaccine, live Injectable Solution" ; rdfs:subClassOf obo:VO_0004856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004858 ] . obo:VO_0004858 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/833084" ; obo:VO_0003198 "833084" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C2608642", "RXAUI: 2944713", "TUI: T200" ; rdfs:label "smallpox vaccine live vaccinia virus 500000000 UNT/ML [ACAM2000]" ; rdfs:subClassOf obo:VO_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004855 ] . obo:VO_0004859 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/29503" ; obo:VO_0003198 "29503" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C0065944", "RXAUI: 436480, 5945194, 6410398", "TUI: T109, T129, T121" ; rdfs:label "meningococcal group C polysaccharide" ; rdfs:subClassOf obo:VO_0000919, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000031 ] . obo:VO_0004860 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/314725" ; obo:VO_0003198 "314725" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0982276", "RXAUI: 1473942", "TUI: T109, T129, T121" ; rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000031 ] . obo:VO_0004861 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1437844" ; obo:VO_0003198 "1437844" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "C3666861", "RXAUI: 5495920", "TUI: T200" ; rdfs:label "meningococcal group C polysaccharide 0.01 MG/ML" ; rdfs:subClassOf obo:VO_0004859 . obo:VO_0004862 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/350967" ; obo:VO_0003198 "350967" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C1167603", "RXAUI: 1545436", "TUI: T200" ; rdfs:label "meningococcal group C polysaccharide 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0004859 . obo:VO_0004863 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1437845" ; obo:VO_0003198 "1437845" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3666862", "RXAUI: 5495921", "TUI: T200" ; rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.01 MG/ML" ; rdfs:subClassOf obo:VO_0004860 . obo:VO_0004864 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/350966" ; obo:VO_0003198 "350966" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1167602", "RXAUI: 1545435", "TUI: T200" ; rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0004860 . obo:VO_0004865 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1437915" ; obo:VO_0003198 "1437915" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3666883", "RXAUI: 5496016", "TUI: T200" ; rdfs:label "MenHibrix Injectable Product" ; rdfs:subClassOf obo:VO_0000031 . obo:VO_0004866 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1437913" ; obo:VO_0003198 "1437913" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3666881", "RXAUI: 5496014", "TUI: T200" ; rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML / meningococcal group C polysaccharide 0.01 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.01 MG/ML [MenHibrix]" ; rdfs:subClassOf obo:VO_0000031, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004861 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004863 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004868 ] . obo:VO_0004867 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000118 "MenHibrix (meningococcal groups C and Y and Haemophilus b tetanus toxoid conjugate vaccine) 0.5 ML Injection" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1437916" ; obo:VO_0003198 "1437916" ; obo:VO_0003560 "0.5 ML Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML / meningococcal group C polysaccharide 0.01 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.01 MG/ML Injection [MenHibrix]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3537927", "RXAUI: 7253596, 7251659, 7250946", "TUI: T200" ; rdfs:label "MENHIBRIX vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0004865, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004866 ] . obo:VO_0004868 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1437843" ; obo:VO_0003198 "1437843" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3666860", "RXAUI: 5495919", "TUI: T200" ; rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.005 MG/ML" ; rdfs:subClassOf obo:VO_0015013 . obo:VO_0004869 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1299785" ; obo:VO_0003198 "1299785" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:comment "CUI: C3159361", "RXAUI: 4624424", "TUI: T129, T121" ; rdfs:label "HUMAN ADENOVIRUS E SEROTYPE 4 STRAIN CL-68578" ; rdfs:subClassOf obo:NCBITaxon_10508 . obo:VO_0004870 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1183840" ; obo:VO_0003198 "1183840" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3237660", "RXAUI: 3840468", "TUI: T200" ; rdfs:label "Menomune A/C/Y/W-135 Injectable Product" ; rdfs:subClassOf obo:VO_0000072 . obo:VO_0004871 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1802483" ; obo:VO_0003198 "1802483" ; oboInOwl:inSubset "organism" ; a owl:Class ; rdfs:comment "CUI: C4083103", "RXAUI: 8240118", "TUI: T129, T121" ; rdfs:label "HUMAN ADENOVIRUS B SEROTYPE 7 STRAIN 55142" ; rdfs:subClassOf obo:NCBITaxon_10508 . obo:VO_0004872 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1153474" ; obo:VO_0003198 "1153474" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3207956", "RXAUI: 3814359", "TUI: T200" ; rdfs:label "Adenovirus Type 4 Vaccine Live Oral Product" ; rdfs:subClassOf obo:VO_0003175 . obo:VO_0004873 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1153475" ; obo:VO_0003198 "1153475" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3207957", "RXAUI: 3814360", "TUI: T200" ; rdfs:label "Adenovirus Type 4 Vaccine Live Pill" ; rdfs:subClassOf obo:VO_0004872 . obo:VO_0004874 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1099935" ; obo:VO_0003198 "1099935" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3153709", "RXAUI: 6337850", "TUI: T200" ; rdfs:label "Adenovirus Type 4 Vaccine Live Delayed Release Oral Tablet" ; rdfs:subClassOf obo:VO_0004873 . obo:VO_0004875 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1099936" ; obo:VO_0003198 "1099936" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3153710", "RXAUI: 6337174, 6364229", "TUI: T200" ; rdfs:label "Adenovirus Type 4 Vaccine Live 32000 UNT Delayed Release Oral Tablet" ; rdfs:subClassOf obo:VO_0004874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004876 ] . obo:VO_0004876 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1099934" ; obo:VO_0003198 "1099934" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3153708", "RXAUI: 3638491", "TUI: T200" ; rdfs:label "Adenovirus Type 4 Vaccine Live 32000 UNT" ; rdfs:subClassOf obo:VO_0003175 . obo:VO_0004877 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1153476" ; obo:VO_0003198 "1153476" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3207958", "RXAUI: 3814361", "TUI: T200" ; rdfs:label "Adenovirus Type 7 Vaccine Live Oral Product" ; rdfs:subClassOf obo:VO_0003176 . obo:VO_0004878 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1153661" ; obo:VO_0003198 "1153661" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3208141", "RXAUI: 3814362", "TUI: T200" ; rdfs:label "Adenovirus Type 7 Vaccine Live Pill" ; rdfs:subClassOf obo:VO_0004877 . obo:VO_0004879 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1099939" ; obo:VO_0003198 "1099939" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3153712", "RXAUI: 6337292", "TUI: T200" ; rdfs:label "Adenovirus Type 7 Vaccine Live Delayed Release Oral Tablet" ; rdfs:subClassOf obo:VO_0004878 . obo:VO_0004880 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1099940" ; obo:VO_0003198 "1099940" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3153713", "RXAUI: 6337842, 6364883", "TUI: T200" ; rdfs:label "Adenovirus Type 7 Vaccine Live 32000 UNT Delayed Release Oral Tablet" ; rdfs:subClassOf obo:VO_0004879, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004881 ] . obo:VO_0004881 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1099938" ; obo:VO_0003198 "1099938" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3153711", "RXAUI: 3638495", "TUI: T200" ; rdfs:label "Adenovirus Type 7 Vaccine Live 32000 UNT" ; rdfs:subClassOf obo:VO_0003176 . obo:VO_0004882 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/568054" ; obo:VO_0003198 "568054" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1600470", "RXAUI: 2283589", "TUI: T200" ; rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.1 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.1 MG/ML [Menomune A/C/Y/W-135]" ; rdfs:subClassOf obo:VO_0000072, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004862 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004864 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004887 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004889 ] . obo:VO_0004883 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658227" ; obo:VO_0003198 "1658227" ; obo:VO_0003560 "meningococcal group A polysaccharide / meningococcal group C polysaccharide / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y Injection [Menomune A/C/Y/W-135]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C4033800", "RXAUI: 7252552", "TUI: T200" ; rdfs:label "Menomune A/C/Y/W-135 Vaccine Injection" ; rdfs:subClassOf obo:VO_0004870 . obo:VO_0004884 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658228" ; obo:VO_0003198 "1658228" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C3887764", "RXAUI: 7253594, 7252562, 7252553", "TUI: T200" ; rdfs:label "Menomune A/C/Y/W-135 Vaccine 0.5 ML Injection" ; rdfs:subClassOf obo:VO_0004883, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004882 ] . obo:VO_0004885 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/207269" ; obo:VO_0003198 "207269" ; obo:VO_0003560 "meningococcal group A polysaccharide 0.1 MG/ML / meningococcal group C polysaccharide 0.1 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.1 MG/ML / MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP Y 0.1 MG/ML Injectable Solution [Menomune A/C/Y/W-135]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0708576", "RXAUI: 3051640, 7253593, 5944304, 1155623", "TUI: T200" ; rdfs:label "Menomune A/C/Y/W-135 Vaccine Injectable Solution" ; rdfs:subClassOf obo:VO_0004870, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004882 ] . obo:VO_0004886 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/314724" ; obo:VO_0003198 "314724" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C0982275", "RXAUI: 1473937", "TUI: T200" ; rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135" ; rdfs:subClassOf obo:VO_0000053 . obo:VO_0004887 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/350965" ; obo:VO_0003198 "350965" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "CUI: C1167601", "RXAUI: 1545434", "TUI: T200" ; rdfs:label "MENINGOCOCCAL POLYSACCHARIDE VACCINE GROUP W-135 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0004886 . obo:VO_0004888 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/29501" ; obo:VO_0003198 "29501" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C0065942", "RXAUI: 436468, 6410396, 2719265, 5945192", "TUI: T200" ; rdfs:label "meningococcal group A polysaccharide" ; rdfs:subClassOf obo:VO_0000919 . obo:VO_0004889 obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/328467" ; obo:VO_0003198 "328467" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "CUI: C1123385", "RXAUI: 1505209", "TUI: T200" ; rdfs:label "meningococcal group A polysaccharide 0.1 MG/ML" ; rdfs:subClassOf obo:VO_0004888 . obo:VO_0004890 obo:IAO_0000115 "The gH1-Qbeta vaccine is a novel pandemic-influenza vaccine produced by covalently linking the globular head domain of haemagglutinin (gH1) from A/California/07/09 produced in E. coli to VLPs from the bacteriophage Qbeta" ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/30573748" ; obo:VO_0003146 "15‚Ä⬵g HA from Influenza A virus (A/California/7/2009(H1N1))" ; obo:VO_0003147 "VLPs from the bacteriophage Qbeta" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "gH1-Qbeta vaccine" ; rdfs:subClassOf obo:VO_0000578, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000200 ] . obo:VO_0004891 obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/29535712" ; obo:VO_0003146 "100‚Ä⬵g CN54gp140" ; obo:VO_0003147 "GLA-AF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "A recombinant uncleaved clade C HIV-1 envelope gp140 protein (CN54gp140)" ; rdfs:label "CN54gp140 + GLA" ; rdfs:subClassOf obo:VO_0000295 . obo:VO_0004892 obo:IAO_0000119 "https://www.advent-gmp.com/about-us/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:comment """ADVENT SRL VIA CRESCENZIO 9 ROMA, ROMA, 00193 Italy +39-0691093692 Company Type: Corporation Subsidiary http://www.hoovers.com/company-information/cs/company-profile.advent_srl.aebb99e74ae57b09.html?aka_re=1""" ; rdfs:label "Advent Srl., Italy" . obo:VO_0004893 obo:IAO_0000115 "Fluenz is a seasonal trivalent live attenuated influenza vaccine (LAIV) administered intranasally. The vaccine contained A/California/07/2009 (H1N1) pdm09-like strain, A/Victoria/361/2011 (H3N2)-like strain, and B/Massachusetts/2/2012-like strain." ; obo:IAO_0000117 "Randi Rita, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/26148331" ; obo:VO_0003146 "Influenza A virus (A/California/7/2009(H1N1)), Influenza A virus (A/Victoria/361/2011(H3N2)), Influenza B virus (B/Massachusetts/02/2012" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluenz" ; rdfs:subClassOf obo:VO_0001178, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0001015 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000694 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004894 obo:IAO_0000115 "quadrivalent seasonal inactivated influenza vaccine 2014 consisting of Influenza A virus (A/California/7/2009(H1N1)), Influenza A virus (A/Texas/50/2012(H3N2)), Influenza B virus (B/Brisbane/60/2008), Influenza B virus (B/Massachusetts/02/2012)" ; obo:IAO_0000117 "Randi Rita, Olilver He" ; obo:IAO_0000119 "Avey et al 2019, paper submitted" ; obo:VO_0003146 "Influenza A virus (A/California/7/2009(H1N1)), Influenza A virus (A/Texas/50/2012(H3N2)), Influenza B virus (B/Brisbane/60/2008), Influenza B virus (B/Massachusetts/02/2012)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "quadrivalent seasonal inactivated influenza vaccine 2014" ; rdfs:subClassOf obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] . obo:VO_0004895 obo:IAO_0000112 "F' (intended to refer to a female biological sex), 'Female', 'Woman', '0' (intended to refer to a female biological sex)" ; obo:IAO_0000115 "A biological sex datum that represents the biological sex of an animal (including human) as being female." ; obo:IAO_0000117 "Paul Fabry, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "female biological sex datum" ; rdfs:subClassOf obo:VO_0001194 . obo:VO_0004896 obo:IAO_0000112 "I' (intended to refer to an intersex biological sex), 'Intersex', 'Hermaphrodite', 'Pseudo-hermaphrodite', '2' (intended to refer to an intersex biological sex)" ; obo:IAO_0000115 "A biological sex datum that represents the biological sex of an animal (including human) as being intersex." ; obo:IAO_0000117 "Paul Fabry, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "intersex biological sex datum" ; rdfs:subClassOf obo:VO_0001194 . obo:VO_0004897 obo:IAO_0000115 "A vaccine against coronavirus infection" ; obo:IAO_0000117 "Hong Yu, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "coronavirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11118 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11118 ] . obo:VO_0004898 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "https://www.fludb.org/brc/fluStrainDetails.spg?strainName=A/Perth/16/2009(H3N2)&decorator=influenza" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment """Recommended by WHO for Vaccines: 2011-2012 Northern Hemisphere 2010 Southern Hemisphere 2011 Southern Hemisphere 2012 Southern Hemisphere 2010-2011 Northern Hemisphere""" ; rdfs:label "Influenza A virus A/Perth/16/2009 (H3N2) antigen" ; rdfs:subClassOf obo:VO_0015085 . obo:VO_0004899 obo:IAO_0000115 "2012-2013 trivalent seasonal inactivated influenza vaccine 2012-2013 Influenza A virus (A/California/7/2009 (H1N1)), Influenza A virus (A/Victoria/361/2011 (H3N2)), and Influenza B virus (B/Wisconsin/1/2010)" ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/?term=30843873" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "2012-2013 seasonal trivalent inactivated influenza vaccine (A/California/7/2009 (H1N1), A/Victoria/361/2011 (H3N2), and B/Wisconsin/1/2010)" ; rdfs:subClassOf obo:VO_0001176, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004901 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ] . obo:VO_0004900 obo:IAO_0000118 "MERS-CoV vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MERS vaccine" ; rdfs:subClassOf obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1335626 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1335626 ] . obo:VO_0004901 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "https://www.drugbank.ca/drugs/DB14396" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus B/Wisconsin/1/2010 antigen" ; rdfs:subClassOf obo:VO_0015086 . obo:VO_0004902 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "https://www.fludb.org/brc/fluStrainDetails.spg?strainName=A/Victoria/361/2011(H3N2)&decorator=influenza" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment """Recommended by WHO for Vaccines: 2013 Southern Hemisphere 2014 Southern Hemisphere 2012-2013 Northern Hemisphere 2013-2014 Northern Hemisphere""" ; rdfs:label "influenza A virus A/Victoria/361/2011 (H3N2) antigen" ; rdfs:subClassOf obo:VO_0015085 . obo:VO_0004903 obo:IAO_0000115 "Inactivated monovalent influenza A/H5N1 (3.75 mcg hemagglutinin [HA] A/Indonesia/05/2005) split-virus (SV) vaccine (Sanofi)" ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/28099485", "https://www.ncbi.nlm.nih.gov/pubmed/30566602" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Inactivated monovalent influenza A/H5N1 (3.75 mcg hemagglutinin [HA] A/Indonesia/05/2005) split-virus (SV) vaccine (Sanofi)" ; rdfs:subClassOf obo:VO_0000065, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004904 ] . obo:VO_0004904 obo:IAO_0000119 "https://www.fludb.org/brc/fluStrainDetails.spg?strainName=A/Indonesia/5/2005(H5N1)&tabName=17535101%20No2&decorator=influenza&context=1544988803656" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Influenza A virus (A/Indonesia/05/2005) antigen" ; rdfs:subClassOf obo:VO_0015085 . obo:VO_0004905 obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884803/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MERS-CoV S protein with alum and CpG adjuvant" ; rdfs:subClassOf obo:VO_0004900, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:VO_0004907 ] . obo:VO_0004906 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "MERS-CoV protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0004907 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "MERS-CoV S protein" ; rdfs:subClassOf obo:VO_0004906 . obo:VO_0004908 obo:IAO_0000115 "A coronavirus vaccine against the infection of SARS-CoV-2 (cause of COVID-19)" ; obo:IAO_0000117 "Oliver He, Philip Huang, Anthony Huffman" ; obo:IAO_0000118 "SARS-CoV-2 vaccine" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/COVID-19_vaccine", "https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/covid-19-vaccines" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 vaccine" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0004909 obo:IAO_0000115 "A shortcut object property that represents a relation between a vaccine and a disease process where the vaccine immunizes a host against a disease process." ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "immunizes against disease process" . obo:VO_0004910 obo:IAO_0000115 "A Plasmodium falciparum vaccine that is composed of aseptic, purified, live (metabolically active), radiation-attenuated, cryopreserved Plasmodium falciparum sporozite." ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000118 "Plasmodium falciparum sporozite Vaccine" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/26469720", "https://www.ncbi.nlm.nih.gov/pubmed/28216244" ; obo:VO_0003159 "Sanaria Inc., Rockville, MD" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PfSPZ Vaccine" ; rdfs:subClassOf obo:VO_0000087 . obo:VO_0004911 obo:IAO_0000115 "The fully infectious PfSPZ are attenuated in vivo by concomitant administration of an anti-malarial drug (chloroquine). Chloroquine kills disease-associated blood stages but does not affect pre-erythrocytic (sporozoite or liver) stages, which are exposed to the host's immune system. Sporozoites-induced protection is mediated by immunity against pre-erythrocytic stages." ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000118 "PfSPZ Chemoprophylaxis Vaccine" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775905/", "https://www.ncbi.nlm.nih.gov/pubmed/26469720", "https://www.ncbi.nlm.nih.gov/pubmed/28199305" ; obo:VO_0003159 "Sanaria Inc., Rockville, MD" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PfSPZ-CVac" ; rdfs:subClassOf obo:VO_0000087 . obo:VO_0004912 obo:IAO_0000115 "Sanaria¬Æ PfSPZ-GA1 consists of purified, aseptic, cryopreserved Pf sporozoites (NF54 strain) genetically attenuated by removal of the b9 and slarp genes to halt development in the early liver stages." ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/26469720" ; obo:VO_0003159 "Sanaria Inc., Rockville, MD" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "The parasite line was generated by the Leiden University Medical Center (LUMC) and RUMC in collaboration with Sanaria. PfŒîb9Œîslarp parasites invade hepatocytes but are incapable of sustaining liver stage development, similar to radiation-attenuated PfSPZ. The potential advantages of PfSPZ-GA1 are that (1) the PfSPZ are homogenous and have a precisely characterized genetic basis for attenuation; (2) manufacturing PfSPZ-GA1 cannot result in accidental exposure of staff to infectious parasites, thereby simplifying the approach to safety of operators and lowering costs. PfSPZ-GA1 also has the potential to induce more efficient protection than the radiation-attenuated PfSPZ Vaccine due to a different pattern of developmental arrest and antigen expression. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077156/" ; rdfs:label "PfSPZ-GA1" ; rdfs:subClassOf obo:VO_0000087 . obo:VO_0004913 obo:IAO_0000115 "a vaccine role that inheres in a vaccine using virus-like particles (VLPs), multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccines." ; obo:IAO_0000117 "Anthony Huffman, Oliver He" ; obo:IAO_0000118 "virus like particle vaccine role" ; obo:IAO_0000119 "https://pubmed.ncbi.nlm.nih.gov/20923267/" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "virus-like particle vaccine role" ; rdfs:subClassOf obo:VO_0000615 . obo:VO_0004914 obo:IAO_0000115 "A vaccine that uses virus-like particles (VLPs), multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome, potentially yielding safer and cheaper vaccines." ; obo:IAO_0000117 "Anthony Huffman, Oliver He" ; obo:IAO_0000118 "virus like particle vaccine" ; obo:IAO_0000119 "https://pubmed.ncbi.nlm.nih.gov/20923267/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "virus-like particle vaccine" ; rdfs:subClassOf obo:VO_0005505, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0004913 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0004913 ] . obo:VO_0004915 obo:IAO_0000115 "vaccine-induced T-helper 1 type immune response that is indicated by the presence of Interferon-gamma production" ; obo:IAO_0000117 "Anthony Huffman, Oliver He" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine specific interferon-γ immune response" ; rdfs:subClassOf obo:VO_0000100 . obo:VO_0004916 obo:IAO_0000115 "vaccine-induced T-helper 1 type immune response that is indicated by the presence of interleukin-2 production" ; obo:IAO_0000117 "Anthony Huffman, Oliver He" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine specific IL-2 immune response" ; rdfs:subClassOf obo:VO_0000100 . obo:VO_0004917 obo:IAO_0000115 "vaccine-induced T-helper 2 type immune response that is indicated by the presence of interleukin-4 production" ; obo:IAO_0000117 "Anthony Huffman, Oliver He" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine specific interleukin-4 response" ; rdfs:subClassOf obo:VO_0000101 . obo:VO_0004918 obo:IAO_0000115 "vaccine-induced T-helper 2 type immune response that is indicated by the presence of interleukin-10 production" ; obo:IAO_0000117 "Anthony Huffman, Oliver He" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine specific interleukin-10 response" ; rdfs:subClassOf obo:VO_0000101 . obo:VO_0004919 obo:IAO_0000115 "vaccine-induced T-helper 1 type immune response that is indicated by the presence of IgG2a production" ; obo:IAO_0000117 "Anthony Huffman, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101669/" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine specific Th1 immune response indicated by IgG2a production" ; rdfs:subClassOf obo:VO_0000100 . obo:VO_0004920 obo:IAO_0000115 "vaccine-induced T-helper 2 type immune response that is indicated by the presence of IgG1 production" ; obo:IAO_0000117 "Anthony Huffman, Oliver He" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101669/" ; oboInOwl:inSubset "vaccine-induced host response" ; a owl:Class ; rdfs:label "vaccine specific Th2 immune response indicated by IgG1 production" ; rdfs:subClassOf obo:VO_0000101 . obo:VO_0004921 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ; rdfs:label "human age" ; rdfs:subClassOf obo:PATO_0000011 . obo:VO_0004922 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ; rdfs:label "child age" ; rdfs:subClassOf obo:VO_0004921 . obo:VO_0004923 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ; rdfs:label "adolescence age" ; rdfs:subClassOf obo:VO_0004921 . obo:VO_0004924 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ; rdfs:label "adult age" ; rdfs:subClassOf obo:VO_0004921 . obo:VO_0004925 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "quality" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ; rdfs:label "senior age" ; rdfs:subClassOf obo:VO_0004921 . obo:VO_0004926 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:label "age range at vaccination" ; rdfs:subClassOf obo:IAO_0000109 . obo:VO_0004927 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ; rdfs:label "human age range at vaccination" ; rdfs:subClassOf obo:VO_0004926 . obo:VO_0004928 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; obo:IAO_0000118 "human age 0 to 12 years at vaccination" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human child age range at vaccination" ; rdfs:subClassOf obo:VO_0004927 . obo:VO_0004929 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; obo:IAO_0000118 "human age 19 to 59 years at vaccination" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human adult age range at vaccination" ; rdfs:subClassOf obo:VO_0004927 . obo:VO_0004930 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; obo:IAO_0000118 "human age 60 and above years at vaccination" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human senior age range at vaccination" ; rdfs:subClassOf obo:VO_0004927 . obo:VO_0004931 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; obo:IAO_0000118 "human age 13 to 18 years at vaccination" ; obo:IAO_0000119 "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855." ; rdfs:label "human adolescence age range at vaccination" ; rdfs:subClassOf obo:VO_0004927 . obo:VO_0004932 obo:IAO_0000115 "A pharmaceutical company that was founded in 1953 by Paul Janssen, is headquartered in Beerse, Belgium, and owned by Johnson & Johnson." ; obo:IAO_0000117 "Oliver He, Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Janssen_Pharmaceutica", "https://www.janssen.com/us/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Janssen Pharmaceutica" . obo:VO_0004933 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 1 to 2 months at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004934 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 4 months at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004935 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 11 to 12 years at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004936 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 4 to 6 years at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004937 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 7 to 11 months at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004938 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 12 to 23 months at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004939 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 2 to 3 years at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004940 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 6 months at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004941 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 7 to 10 years at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004942 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 19 to 26 years at vaccination" ; rdfs:subClassOf obo:VO_0004929 . obo:VO_0004943 obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age 27 to 59 years at vaccination" ; rdfs:subClassOf obo:VO_0004929 . obo:VO_0004944 obo:IAO_0000115 "A human child age range at vaccination with the range from the birth to one month after birth at when a vaccination is taken. HepB vaccination is sometimes taken within 12 hours after birth." ; obo:IAO_0000117 "Anna Maria Masci, Anthony Huffman, Oliver He, Jie Zheng" ; obo:IAO_0000118 "newborn age range at human vaccination" ; obo:IAO_0000119 "https://www.cdc.gov/vaccines/parents/diseases/hepb.html" ; oboInOwl:inSubset "data item" ; a owl:Class ; rdfs:comment "The human age is classified into four categories as Child (0-12 years), Adolescence (13-18 years), Adult (19-59 years) and Senior Adult (60 years and above) which is discussed in the paper. Reference: https://ieeexplore.ieee.org/abstract/document/6416855.", "https://www.cdc.gov/vaccines/vpd/vaccines-age.html" ; rdfs:label "human age within one month at vaccination" ; rdfs:subClassOf obo:VO_0004928 . obo:VO_0004945 obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000118 "康希诺生物"@zh ; obo:IAO_0000119 "http://www.cansinotech.com/", "https://en.wikipedia.org/wiki/CanSino_Biologics" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "CanSino Biologics" . obo:VO_0004946 obo:IAO_0000115 "A German biotechnology company that is dedicated to the development and manufacture of active immunotherapies for a patient-specific approach to the treatment of serious diseases." ; obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/BioNTech" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "BioNTech" . obo:VO_0004947 obo:IAO_0000115 "An American multinational pharmaceutical corporation headquartered in New York City." ; obo:IAO_0000117 "Philip, Oliver" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Pfizer", "https://www.pfizer.com/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Pfizer Inc." . obo:VO_0004948 obo:IAO_0000115 "A British-Swedish multinational pharmaceutical and biopharmaceutical company with its headquarters in Cambridge, United Kingdom and S√∂dert√§lje, Sweden. AstraZeneca makes products for major disease areas including cancer, cardiovascular, gastrointestinal, infection, neuroscience, respiratory and inflammation." ; obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/AstraZeneca" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "AstraZeneca" . obo:VO_0004949 obo:IAO_0000117 "Philip, Oliver" ; obo:IAO_0000119 "https://www.cnbg.com.cn/", "https://www.trialsitenews.com/chinas-beijing-institute-of-biological-products-covid-19-vaccine-reportedly-ready-for-phase-iii/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Beijing Institute of Biological Products" . obo:VO_0004950 obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000118 "Sinopharm"@en, "Sinopharm Group"@en, "国药控股股份有限公司"@zh ; obo:IAO_0000119 "http://www.sinopharm.com/1156.html", "https://en.wikipedia.org/wiki/Sinopharm_Group" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Sinopharm Group Co., Ltd." . obo:VO_0004951 obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000119 "http://www.wibp.com.cn" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Wuhan Institute of Biological Products" . obo:VO_0004952 obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Gamaleya_Research_Institute_of_Epidemiology_and_Microbiology", "https://gamaleya.org/en/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Gamaleya Research Institute" . obo:VO_0004953 obo:IAO_0000117 "Philip, Oliver" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Moderna", "https://www.modernatx.com/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Moderna" . obo:VO_0004954 obo:IAO_0000115 "A biopharmaceutical company headquartered in Beijing, China" ; obo:IAO_0000118 "Sinovac"@en ; obo:IAO_0000119 "http://www.sinovac.com/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Sinovac Biotech Ltd" . obo:VO_0004955 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "AnGes, Inc." . obo:VO_0004956 obo:IAO_0000115 "An American biotech company focused on the discovery, development and commercialization of therapeutics for rare diseases with focus on RNA" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Arcturus_Therapeutics" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Arcturus Therapeutics" . obo:VO_0004957 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Beijing Minhai Biotechnology Co., Ltd." . obo:VO_0004958 obo:IAO_0000117 "Philip Huang, Oliver He" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Vaxxinity" . obo:VO_0004959 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Beijing Wantai Biological Pharmacy" . obo:VO_0004960 obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "FBRI SRC VB VECTOR"@en, "Federal Budgetary Research Institution State Research Center of Virology and Biotechnology"@en, "Vector Institute"@en ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "State Research Center of Virology and Biotechnology VECTOR" . obo:VO_0004961 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Genexine, Inc." . obo:VO_0004962 obo:IAO_0000115 "An American biotechnology company focused on the discovery, development, and commercialization of synthetic DNA products for treating cancers and infectious diseases" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Inovio_Pharmaceuticals" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Inovio Pharmaceuticals, Inc." . obo:VO_0004963 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Kentucky Bioprocessing, Inc." . obo:VO_0004964 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Anhui Zhifei Longcom Biopharmaceutical Co., Ltd." . obo:VO_0004965 obo:IAO_0000115 "A manufacturer of immunobiological drugs including vaccines in India" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Serum_Institute_of_India" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Serum Institute of India" . obo:VO_0004966 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Zydus Cadila" . obo:VO_0004967 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Adimmune Corporation" . obo:VO_0004968 obo:IAO_0000115 "A China-based company principally engaged in the research, development, production and distribution of vaccines, monoclonal antibodies and blood products" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://www.reuters.com/companies/300142.SZ" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Walvax Biotechnology Co., Ltd." . obo:VO_0004969 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Symvivo" . obo:VO_0004970 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Chulalongkorn University" . obo:VO_0004971 obo:IAO_0000115 "A public research university in London" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Imperial_College_London" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Imperial College London" . obo:VO_0004972 obo:IAO_0000115 "A Canadian biotechnology company focused on the discovery, development, and commercialization of virus-like particles using plants as \"bioreactors\" to produce proteins as candidate vaccines and medications" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Medicago_Inc." ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Medicago Inc." . obo:VO_0004973 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Entos Pharmaceuticals" . obo:VO_0004974 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "ReiThera Srl" . obo:VO_0004975 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "ImmunityBio, Inc." . obo:VO_0004976 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "NantKwest, Inc." . obo:VO_0004977 obo:IAO_0000115 "The teaching hospital of the University of Hamburg and one of the largest hospitals in Hamburg, Germany" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/University_Medical_Center_Hamburg-Eppendorf" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "University Medical Center Hamburg-Eppendorf" . obo:VO_0004978 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Medigen, Inc." . obo:VO_0004979 obo:IAO_0000115 "A public research university in Chengdu, Sichuan, China" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "四川大学"@zh ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Sichuan_University" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Sichuan University" . obo:VO_0004980 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Vaxine Pty Ltd." . obo:VO_0004981 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Instituto Finlay de Vacunas" . obo:VO_0004982 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Clover Biopharmaceuticals, Inc." . obo:VO_0004983 obo:IAO_0000115 "A French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "Pasteur Institute"@en ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Pasteur_Institute" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Institut Pasteur" . obo:VO_0004984 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "COVAXX" . obo:VO_0004985 obo:IAO_0000115 "A public research university located primarily in Brisbane, Queensland, Australia" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/University_of_Queensland" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "University of Queensland" . obo:VO_0004986 obo:IAO_0000115 "An American biotechnology company focused on the discovery, development, and commercialization of oral recombinant vaccines" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Vaxart" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Vaxart, Inc." . obo:VO_0004987 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine formed from a lipid nanoparticle-formulated trimerized SARS-CoV-2 receptor-binding domain" ; obo:IAO_0000117 "Philip Huang, Rohit Goru, Oliver He" ; obo:IAO_0000118 "BNT162b2", "PF-07302048", "Tozinameran" ; obo:IAO_0000119 "PubMed: 32839784", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php", "https://en.wikipedia.org/wiki/Tozinameran", "https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/Pfizer-BioNTech.html", "https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/pfizer-biontech-covid-19-vaccine", "https://www.fda.gov/media/144246/download" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Comirnaty" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004947 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004988 obo:IAO_0000117 "Oliver He, Philip Huang" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "SARS-CoV-2 protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0004989 obo:IAO_0000116 "Replaced term with S protein of SARS-CoV-2 Wuhan strain (PR_P0DTC2) for ontology harmonization" ; obo:IAO_0000117 "Anthony Huffman" ; a owl:Class ; rdfs:label "obsolete S protein of SARS-CoV-2" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0004990 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "E protein of SARS-CoV-2" ; rdfs:subClassOf obo:VO_0004988 . obo:VO_0004991 obo:IAO_0000115 "BBV152 (also known as Covaxin) is an inactivated COVID-19 vaccine that is developed by Bharat Biotech in collaboration with the Indian Council of Medical Research." ; obo:IAO_0000117 "Philip Huang, Rohit Guru, Oliver He" ; obo:IAO_0000118 "BBV152" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php", "https://en.wikipedia.org/wiki/BBV152", "https://go.drugbank.com/drugs/DB15847" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVAXIN" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0004992 obo:IAO_0000115 "A recombinant coronavirus-like particle SARS-CoV-2 vaccine developed by Medicago" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04636697" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CoVLP" ; rdfs:subClassOf obo:VO_0005418, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0004993 obo:IAO_0000115 "A P. falciparum malaria vaccine that is formed by tull length CS-expressing replication-deficient recombinant human adenovirus 35." ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000119 "PMID:18455276" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "This is a term requested by Randi for the HIPC/ImmPort work" ; rdfs:label "Ad35.CS.01 malaria vaccine" ; rdfs:subClassOf obo:VO_0000087 . obo:VO_0004994 obo:IAO_0000115 "A SARS-CoV-2 trimeric S protein subunit vaccine." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04405908" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SCB-2019" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003153 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004982 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004995 obo:IAO_0000115 "A SARS-CoV-2 S1-RBD-protein based vaccine developed by Vaxxinity" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04545749" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "UB-612" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004958 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004996 obo:IAO_0000115 "A SARS-CoV-2 replication-defective human adenovirus type 5/35 vector based vaccine expressing the S protein." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04666012" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AdCLD-CoV19" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004997 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0004997 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Cellid Co., Ltd." . obo:VO_0004998 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "University Medical Center Groningen" . obo:VO_0004999 obo:IAO_0000115 "A SARS-CoV-2-RBD-Fc fusion protein designed to induce or boost a Th1/Th2 mixed immune response in patients against the Receptor Binding Domain (RBD) of the novel coronavirus spike protein." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://www.akstonbio.com/programs/covid-19-vaccine/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AKS-452" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004998 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0005000 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCAGGSP7. This plasmid has a polylinker containing KpnI, XhoI, ClaI, EcoRV, SmaI, Not1 and Sac1 sites inserted into the EcoRI site of pCAGGS." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCAGGSP7 DNA vaccine plasmid" ; rdfs:seeAlso "PMID:9711802" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005001 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCAGGS/MCS. This plasmid has a chicken beta-actin promoter, contains a multiple cloning site between the EcoRI and BglII sites of the rabbit beta-globin gene, and has restriction sites for the enzymes SacI, ClaI, NsiI, Asp718, SmaI, SphI, XhoI, and NheI." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCAGGS/MCS DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 9261394" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005002 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pWRG. This plasmid is a eukaryotic expression plasmid that contains the immediate early promoter and intron A of human cytomegalovirus." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pWRG DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 10403592" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005003 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pHW2000. This plasmid is derived from pHW12 and contains part of the human pol I promoter and murine terminator sequences, a CMV promoter, and the polyadenylation signal of the gene encoding bovine growth hormone." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pHW2000 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 10662626" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005004 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCMV/R. This plasmid is a mammalian expression vector with a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV/R DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 20660192" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005005 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label VRC-9123." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "This plasmid was prepared under Good Manufacturing Practices at 4 mg/mL in phosphate buffered saline (PBS)." ; rdfs:label "VRC-9123 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 21975270" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005006 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pPJV7563. This plasmid has a human cytomegalovirus immediate early promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pPJV7563 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 20544035" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005007 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label p188. This plasmid is a replication-defective derivative of pP1/H7." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "p188 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 8212843" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005008 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label VR10551. This plasmid contains a human cytomegalovirus immediate early 1 promoter, a kanamycin resistance gene, intron A and a modified rabbit b-globin terminator." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "VR10551 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 17637571" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005009 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label VCL-1632. This plasmid contains a CMV promoter, kanamycin resistance gene, the murine Œ∫ constant region sequence, a translational enhancer, the murine IgG2a heavy-chain sequence, and a translation terminator. This plasmid is derived from pUC-18." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "VCL-1632 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 12384547" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005010 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSport-B-gal. This plasmid contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSport-B-gal DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 12496961" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005011 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSin-B-gal. This plasmid contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSin-B-gal DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 10646851" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005012 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pLXSHD. This plasmid has a murine leukemia virus enhancer-promoter LTR." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pLXSHD DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 7533183" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005013 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label WRG/BEN. This plasmid is based off of pWRG7077. It contains a CMV promoter and a kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "WRG/BEN DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 9739060" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005014 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pNGVL4a. This plasmid has a CMV promoter and kanamycin and ampicillin resistance genes." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "There is an extra immunostimulatory sequence (450 bp) in pNGVL4a plasmid compared to pNGVL3" ; rdfs:label "pNGVL4a DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 11818167" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005015 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pNGVL3. This plasmid has a CMV promoter and kanamycin and ampicillin resistance genes." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pNGVL3 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 11818167" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005016 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label SINCp B-gal. This plasmid contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "SINCp B-gal DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 17024104" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005017 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label Synchotrope TA2M. This plasmid is 3683 base pairs in length and has two copies of the murine CpG immune stimulatory sequence AACGTT inserted." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "It has been shown that plasmid half-life in human serum in vitro is 20 minutes" ; rdfs:label "Synchotrope TA2M DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 12833467" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005018 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCMV/myc/ER. This plasmid is 5066 base pairs in length and contains a CMV promoter and ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2236/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV/myc/ER DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005019 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pPA63-LAMP1." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pPA63-LAMP1 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 19130551" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005020 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSecTag2B. This plasmid is 5163 base pairs in length and contains a CMV promoter and ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Invitrogen:http://tools.invitrogen.com/content/sfs/manuals/psectag2_man.pdf; Sequence: http://tools.invitrogen.com/content/sfs/vectors/psectag2b_seq.txt" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSecTag2B DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005021 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pTPA-PA63-LAMP1." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pTPA-PA63-LAMP1 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 19130551" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005022 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pTPA-PA63." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pTPA-PA63 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 19130551" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005023 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label VR2210. This plasmid contains a CMV promoter and kanamycin resistance gene. It was created through ligation of fragments of digested plasmid VR1012, hTPA, and B. burgdorferi B31 ospA." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "VR2210 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 8985201" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005024 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCMV-TPA/ZS7. This plasmid contains a CMV promoter and is generated from pCMV-ZS7 by attaching hTPA to ospC ZS7." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV-TPA/ZS7 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 12941385; PMID: 10580194" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005025 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pABB-CRS2. This plasmid is a derivative of pCVD442 and contains a chloramphenicol resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pABB-CRS2 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 11562461" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005026 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pMASIA-tgD. This plasmid is based off of pMASIA and contains a CMV promoter and kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pMASIA-tgD DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 12466473" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005027 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCMVi-UB. This plasmid was built from pCMV-5 and contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMVi-UB DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 10433551" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005028 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCI30. This plasmid contains a CMV promoter, ampicillin resistance gene, T7 RNA polymerase promoter, a multiple cloning region and a 6xHis tag coding sequence." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCI30 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 17239501; PMID: 11567754" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005029 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCP15/60." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCP15/60 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005030 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pUMVC3. This plasmid is 4030 base pairs in length and contains a CMV promoter and kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Aldevron: http://www.aldevron.com/products/dnas/umvc_expression/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pUMVC3 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 12654810" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005031 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pcDNA1. This plasmid is 4000 base pairs in length and contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: https://www.addgene.org/vector-database/2089/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA1 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005032 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCAT. This plasmid is 4364 base pairs in length and contains an ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2051/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCAT DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005033 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pGT36. This plasmid is a derivative of pcDNA3 and contains a CMV promoter and a kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pGT36 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 9569471]" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005034 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label VR1040. This plasmid contains four copies of the mouse immunostimulatory sequence and is similar to VR1012." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "VR1040 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 11883007" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005035 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pcTPA. This plasmid is based on pcDNA3 and contains the hTPA signal sequence." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcTPA DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 16122850" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005036 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pMV10.1. This plasmid contains a CMV promoter and a kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pMV10.1 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 16125280" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005037 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pET11d. This plasmid is 5674 base pairs in length and contains an ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2628/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pET11d DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 16520093" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005038 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pUMVC4b. This plasmid is 4478 base pairs in length and contains a CMV promoter and kanamycin and ampicillin resistance genes." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Aldevron: http://www.aldevron.com/products/dnas/umvc_expression/; Sequence: https://system.netsuite.com/c.606687/pUMVC4a.txt" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pUMVC4b DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005039 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pRC. This plasmid is 7400 base pairs in length and contains CMV and RSV promoters." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRC DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 9879611" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005040 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pAK-4. This plasmid is 6600 base pairs in length and contains a CMV promoter and kanamycin and ampicillin resistance genes." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pAK-4 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 16157425" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005041 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCMVi(-H3)Ubs. This plasmid contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMVi(-H3)Ubs DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 10438054" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005042 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label Auxo-GTU." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "patent applications, PCT/FI02/00379 filed 03.05.2002 and PCT/FI2004/ 000540 filed 15.09.2004" ; rdfs:label "Auxo-GTU DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 16359234" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005043 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCMN160. This plasmid has a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMN160 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 9142121" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005044 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label V1Jns. This plasmid contains the human CMV promoter, enhancer and intron A as well as the polyadenylation sequences of bovine growth hormone." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "V1Jns DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 9127013" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005045 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pND-14. This plasmid contains a CMV promoter, ampicillin resistance gene, a tissue plasminogen activator leader sequence, a bovine growth hormone terminator, and constitutive transport element from simian retrovirus." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pND-14 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 15149785" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005046 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSecTag2A. This plasmid is 5159 base pairs in length and contains a CMV promoter and ampicillin reisistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Invitrogen: http://tools.invitrogen.com/content/sfs/manuals/psectag2_man.pdf; Sequence: http://tools.invitrogen.com/content/sfs/vectors/psectag2a_seq.txt" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSecTag2A DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005047 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pRc/CMV-HBs(S). This plasmid is 5618 base pairs in length and contains a CMV promoter and ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Bioresearch Online: http://www.bioresearchonline.com/doc/pRcCMV-HBsS-0001" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Also known as pCMV-S" ; rdfs:label "pRc/CMV-HBs(S) DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005048 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pcDNA." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 15839423" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005049 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label proVAX. This plasmid contains a CMV promoter and a hCG-Œ≤ leader sequence." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "proVAX DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 17310492" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005050 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label p1012." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "p1012 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 11117750" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005051 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pUSE-. This plasmid is a mammalian expression vector derived from pCI-neo." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pUSE- DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 11507187" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005052 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label APL023." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "APL023 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 17241713" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005053 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pEGFP-N1. This plasmid is 4733 base pairs in length and contains a CMV promoter and kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2491/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pEGFP-N1 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005054 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCDL-SRa296. This plasmid is 3700 base pairs in length and contains a SRalpha promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2084/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCDL-SRa296 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 2827008" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005055 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pUSK." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pUSK DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 15121294" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005056 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pUBIQ. This plasmid is derived from pGEM3 and contains a CMV promoter and an ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pUBIQ DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 12922097" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005057 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/Hygro(-). This plasmid is 5596 base pairs in length and contains a CMV promoter and an ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2105/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Differs from other pcDNA3.1 in drug resistance; +/- refers to orientation of f1 ori" ; rdfs:label "pcDNA3.1/Hygro(-) DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005058 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCMV3ISS. This plasmid is a eukaryotic expression vector." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV3ISS DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 18951941" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005059 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pWRG7079. This plasmid contains a CMV promoter and a kanamycin resistance gene and differs from pWRG7077 by the insertion of a TPA sequence." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pWRG7079 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 12922144" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005060 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pVR1020. This plasmid contains a CMV promoter and kanamycin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVR1020 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 11292786" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005061 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label nkCMVintpolyli. This plasmid contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "nkCMVintpolyli DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 8666931" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005062 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1/V5-His-TOPO. This plasmid is 5523 base pairs in length and contains a CMV promoter and ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/5587/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA3.1/V5-His-TOPO DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005063 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pIRES1neo. This plasmid is 5257 base pairs in length and contains an ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Metalife: http://www.metalife.com/Genbank/1899169" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pIRES1neo DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005064 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pRc/RSV. This plasmid is 5224 base pairs in length and contains a RSV LTR promoter and ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/3908/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRc/RSV DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005065 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCI-TPA. This plasmid contains the N-terminal signal sequence of TPA." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCI-TPA DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 19428891" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005066 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCSIVgag." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCSIVgag DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 18000037" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005067 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pVacc4. This plasmid is a derivative of pVacc1 and contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pVacc4 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 15004179" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005068 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pBC12B1. This plasmid is a eukaryotic expression vector." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pBC12B1 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 10948115" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005069 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pGFP. This plasmid is 3300 base pairs in length and contains a lac promoter and an ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Clontech: http://www.clontech.com/xxclt_ibcGetAttachment.jsp?cItemId=17740" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pGFP DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005070 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pCMV-beta. This plasmid is 7164 base pairs in length and contains a CMV promoter and ampicllin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2245/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pCMV-beta DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005071 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pSW3891. This plasmid contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pSW3891 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 16919703" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005072 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pJW4304. This plasmid is 5132 base pairs in length and contains a CMV promoter." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "NIH AIDS Reagent Program: https://www.aidsreagent.org/reagentdetail.cfm?t=cloning_vectors&id=76" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pJW4304 DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005073 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pGT146-mIL-12." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pGT146-mIL-12 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 18694965" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005074 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pDNAVACC." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pDNAVACC DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 21134447" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005075 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label VR1055. This plasmid is derived from pUC19 and contains a CMV promoter, kanamycin resistance gene, a cloning polylinker, and a transcriptional terminator region derived from the rabbit beta-globin gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "VR1055 DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 9990062" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005076 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pRSC." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pRSC DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 21185849" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005077 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pcDNA3.1(Zeo)+. This plasmid is 5015 base pairs in length and contains a zeocin selectable marker, a CMV promoter, and an ampicillin resistance gene." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; obo:IAO_0000119 "Addgene: http://www.addgene.org/vector-database/2110/" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "pcDNA3.1(Zeo)+ DNA vaccine plasmid" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005078 obo:IAO_0000115 "A DNA vaccine plasmid vector that has the plasmid label pVF." ; obo:IAO_0000117 "Rebecca Racz, Yongqun He" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:comment "Also known as pVAX-Flag" ; rdfs:label "pVF DNA vaccine plasmid" ; rdfs:seeAlso "PMID: 23026687" ; rdfs:subClassOf obo:VO_0000435 . obo:VO_0005079 obo:IAO_0000115 "A SARS-CoV-2 vaccine consisting of autologous dendritic cells previously loaded ex vivo with spike protein." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04386252" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AV-COVID-19" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005080 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "AIVITA Biomedical, Inc." . obo:VO_0005081 obo:IAO_0000115 "A SARS-CoV-2 vaccine that includes a protein antigen, SARS-CoV-2 Spike RBD, adsorbed to the adjuvant Alhydrogel (Alum), in combination with another approved adjuvant, CpG 1018" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://www.biologicale.com/news.html" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Corbevax" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005082 obo:IAO_0000115 "An authorized SARS-CoV-2 protein subunit vaccine based on recombinant RBD subunits manufactured by the Center for Genetic Engineering and Biotechnology (CIGB)." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "CIGB-66" ; obo:IAO_0000119 "https://rpcec.sld.cu/en/trials/RPCEC00000345-En" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Abdala" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005083 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine based on recombinant RBD subunits manufactured by the Center for Genetic Engineering and Biotechnology (CIGB)." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://rpcec.sld.cu/en/trials/RPCEC00000345-En" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CIGB-669" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005084 obo:IAO_0000115 "A SARS-CoV-2 inactivated virus vaccine by Shenzhen Kangtai Biological Products and Beijing Minhai Biotechnology Co." ; obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000119 "NCT04852705", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "KCONVAC" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005085 obo:IAO_0000115 "A stabilised pre-fusion SARS-CoV-2 spike protein vaccine produced in a baculovirus expression system and manufactured by Sanofi Pasteur and GlaxoSmithKline" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "CoV2 preS dTM" ; obo:IAO_0000119 "PubMed ID: 33887209" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VAT00002" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0005086 obo:IAO_0000115 "Sanofi S.A. is a French multinational pharmaceutical company headquartered in Paris, France." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Sanofi" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Sanofi S.A." . obo:VO_0005087 obo:IAO_0000115 "An influenza virus vector SARS-CoV-2 vaccine administered as an intranasal spray manufactured by University of Hong Kong, Xiamen University, and Beijing Wantai Biological Pharmacy." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "http://www.chictr.org.cn/showprojen.aspx?proj=55421" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DelNS1-2019-nCoV-RBD-OPT1" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005088 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine that relies on chemically synthesized peptide antigens of SARS-CoV-2 proteins, conjugated to a carrier protein and adsorbed on an aluminum-containing adjuvant (aluminum hydroxide)." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04527575", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EpiVacCorona" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005089 obo:IAO_0000115 "A SARS-CoV-2 plasmid DNA vaccine developed by GeneOne Life Science." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04673149" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GLS-5310" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005090 obo:IAO_0000115 "A rVSV-SARS-CoV-2-S vaccine¬†developed by the Israel Institute for Biological Research (IIBR)" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "Brilife" ; obo:IAO_0000119 "NCT04608305" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IIBR-100" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005091 obo:IAO_0000115 "A SARS-CoV-2 recombinant vector vaccine by Shenzhen Geno-Immune Medical Institute" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04276896" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LV-SMENP-DC" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005092 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine with recombinant SARS-CoV-2 spike (S) protein and aluminum phosphate adjuvant" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04683484" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Nanocovax" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005093 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine manufactured by the Research Institute for Biological Safety Problems (Republic of Kazakhstan)" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "QazCovid-in" ; obo:IAO_0000119 "NCT04691908", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "QazVac" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005094 obo:IAO_0000115 "A SARS-CoV-2 virus-like particle vaccine that contains the Receptor Binding Domain (RBD) of the SARS-CoV-2 spike (S) protein and is adjuvanted with aluminum." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "ACTRN12620001308987" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RBD-HBsAg VLP" ; rdfs:subClassOf obo:VO_0005205, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005095 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine by West China Hospital" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04640402" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombinant SARS-CoV-2 vaccine (Sf9 cell)" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005096 obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "A SARS-CoV-2 recombinant protein vaccine¬†that uses the Baculovirus expression vector system", "https://www.shionogi.com/content/dam/shionogi/global/news/pdf/2020/12/e-201216.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S-268019" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005097 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine developed by Finlay Vaccine Institute (IFV)" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "FINLAY-FR-2" ; obo:IAO_0000119 "https://rpcec.sld.cu/en/trials/RPCEC00000347-En" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Soberana 02" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005098 obo:IAO_0000115 "A SARS-CoV-2 vaccine candidate that uses a measles virus vector platform, and is made by Merck. Development of the vaccine was discontinued on January 25, 2021." ; obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000119 "https://www.merck.com/news/merck-discontinues-development-of-sars-cov-2-covid-19-vaccine-candidates-continues-development-of-two-investigational-therapeutic-candidates/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V591" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005099 obo:IAO_0000115 "A SARS-CoV-2 inactivated, Vero-cell based vaccine adjuvanted with aluminum and CpG 1018. It uses the manufacturing platform of Valneva‚Äôs commercial Japanese encephalitis (JE) vaccine" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://valneva.com/research-development/covid-19-vla2001/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VLA2001" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005100 obo:IAO_0000115 "'A SARS DNA vaccine that is made from recombinant plasmid containing nucleocapsid protein (N) sequence constructed then expressed and purified from E. coli bacteria‚Äô" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5732" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:16423399" ; rdfs:label "SARS N protein DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5732" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005101 obo:IAO_0000115 "'A SARS DNA combination vaccine that is made from recombinant plasmids‚Äô containing membrane protein (M) and nucleocapsid protein (N) sequences constructed then expressed and purified from E. coli bacteria‚Äô" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5733" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:16423399" ; rdfs:label "SARS N + SARS M DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5733" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005102 obo:IAO_0000115 "'A SARS DNA vaccine that is made from recombinant plasmid containing membrane protein (M) sequence constructed then expressed and purified from E. coli bacteria‚Äô" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5731" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:16423399" ; rdfs:label "SARS M protein DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5731" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005103 obo:IAO_0000115 "'A SARS DNA vaccine that is made from oral live-attenuated auxotrophic S. typhimurium aroA strain SL7207 that contained CTLA4HingeSARS800 with SARS-CoV S protein‚Äò" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5738" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:15993989" ; rdfs:label "Salmonella-CTLA4-S SARS DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5738" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005104 obo:IAO_0000115 "A SARS DNA vaccine that is made from intraperitoneal recombinant spike polypeptide generated by amplififying gene encoding amino acids residues 14-667 of S protein that was cloned BamHI and KpnI sites of vector pQE-31 that was generated by Escherichia coli" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5734" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:15993989" ; rdfs:label "Recombinant SARS spike polypeptide vaccine" ; rdfs:seeAlso "VIOLIN ID: 5734" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ] . obo:VO_0005105 obo:IAO_0000115 "A SARS DNA vaccine that is made from CTLA4HingeSARS800 DNA with SARS-CoV S protein" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5737" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:15993989" ; rdfs:label "SARS CTLA4-S DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5737" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005106 obo:IAO_0000115 "A SARS DNA vaccine that is made from tpa-optimize800 DNA with SARS-CoV S protein" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5736" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:15993989" ; rdfs:label "SARS tPA-S DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5736" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005107 obo:IAO_0000115 "A SARS DNA vaccine made from CTLA4HingeSARS800 DNA with SARS-CoV S protein" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5739" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:15993989" ; rdfs:label "Salmonella-tPA-S SARS DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5739" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005108 obo:IAO_0000115 "A SARS recombinant vector vaccine that is made from of the highly attenuated modified vaccinia virus Ankara (MVA) containing the gene encoding full-length SARS-CoV S" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5729" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:23142821" ; rdfs:label "SARS MA-ExoN vaccine" ; rdfs:seeAlso "VIOLIN ID: 5729" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005109 obo:IAO_0000115 "A SARS recombinant vector vaccine that is made from recombinant MA15 virulent mouse-adapted SARS-CoV (MA15) background of E-deleted vaccine candidate (rMA15-ŒîE)" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5728" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:16423399" ; rdfs:label "SARS rMA15-ΔE vaccine" ; rdfs:seeAlso "VIOLIN ID: 5728" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005110 obo:IAO_0000115 "A SARS recombinant vector vaccine that is made from a recombinant live-attenuated modified vaccinia virus Ankara (MVA) that had a full-length SARS-CoV envelope Spike (S) glycoprotein gene introduced into the deletion III region of the MVA genome." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5726" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:15708987" ; rdfs:label "SARS ADS-MVA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5726" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005111 obo:IAO_0000115 "A MERS subunit vaccine that has a combined adjuvant of aluminum hydroxide and CpG oligodeoxynucleotides." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5714" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:29618723" ; rdfs:label "MERS-CoV S vaccine adjuvanted with CpG and Alum" ; rdfs:seeAlso "VIOLIN ID: 5714" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005112 obo:IAO_0000115 "A MERS inactivated whole virus vaccine that has a combined adjuvant that has a combined adjuvant of aluminum hydroxide and CpG oligodeoxynucleotides." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5721" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:29618723" ; rdfs:label "Inactivated whole MERS-CoV (IV) vaccine with CpG and Alum" ; rdfs:seeAlso "VIOLIN ID: 5721" ; rdfs:subClassOf obo:VO_0004900, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_1335626 ] . obo:VO_0005113 obo:IAO_0000115 "A SARS recombinant vector vaccine made from a recombinant form of the highly attenuated modified vaccinia virus Ankara (MVA) containing the gene encoding full-length SARS-CoV S" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5725" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:15096611" ; rdfs:label "SARS MVA/S vaccine" ; rdfs:seeAlso "VIOLIN ID: 5725" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005114 obo:IAO_0000115 "A SARS inactivated vaccine made from whole killed (inactivated by beta-propiolactone) SARS-CoV" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5730" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:16476986" ; rdfs:label "β-propiolactone-inactivated SARS-CoV vaccine" ; rdfs:seeAlso "VIOLIN ID: 5730" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0005115 obo:IAO_0000115 "A SARS recombinant vector vaccine made of combination of two adenovirus-based vectors, one expressing the nucleocapsid (N) and the other expressing the spike (S) protein" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5727" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:16476986" ; rdfs:label "SARS Ad S/N vaccine" ; rdfs:seeAlso "VIOLIN ID: 5727" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005116 obo:IAO_0000115 "A MERS recombinant vector vaccine made of a recombinant adenoviral vector encoding the the S1 extracellular domain of S protein" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5719" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:25192975" ; rdfs:label "Ad5.MERS-S1 vaccine" ; rdfs:seeAlso "VIOLIN ID: 5719" ; rdfs:subClassOf obo:VO_0004900, [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0001081 ] . obo:VO_0005117 obo:IAO_0000115 "A MERS recombinant vector vaccine made of a recombinant adenoviral vector encoding the full-length MERS-CoV S protein (Ad5.MERS-S)" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5720" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:25192975" ; rdfs:label "Ad5.MERS-S vaccine" ; rdfs:seeAlso "VIOLIN ID: 5720" ; rdfs:subClassOf obo:VO_0004900, [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0001081 ] . obo:VO_0005118 obo:IAO_0000115 "A MERS DNA vaccine made of plasmid that encoded S1 subunit only" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5715" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:26218507" ; rdfs:label "MERS England1 S1 protein subunit Vaccine" ; rdfs:seeAlso "VIOLIN ID: 5715" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005119 obo:IAO_0000115 "A MERS combination vaccine made of made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein and a DNA vaccine that is a plasmid that encoded S1 subunit" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5717" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:26218507" ; rdfs:label "MERS England1 S DNA + England1 S protein subunit vaccine" ; rdfs:seeAlso "VIOLIN ID: 5717" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005120 obo:IAO_0000115 "A MERS DNA vaccine made of the VRC8400 plasmid that encodes the full-length, membrane anchore MERS spike protein" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5716" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:26218507" ; rdfs:label "MERS England1 S DNA Vaccine" ; rdfs:seeAlso "VIOLIN ID: 5716" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005121 obo:IAO_0000115 "A MERS subunit vaccine made of neutralizing monoclonal antibodiesagainst MERS-CoV which bind to the ribosomal binding domain (RBD) of the MERS-CoV S protein that was expressed by baculovirus-insect cell sf9-derived recombinant MERS-CoV." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5723" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:28536429" ; rdfs:label "MERS rRBD plus alum vaccine" ; rdfs:seeAlso "VIOLIN ID: 5723" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005122 obo:IAO_0000115 "A MERS DNA vaccine made of plasmid that encodes the first 725 amino acids of S from MERS-CoV" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5718" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:28314561" ; rdfs:label "MERS-CoV pcDNA3.1-S1 DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5718" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005123 obo:IAO_0000115 "A MERS recombinant vector virus made from chimeric virus based on the vesicular stomatitis virus (VSV) in which the G gene was replaced by MERS-CoV S gene (VSVŒîG-MERS)." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5722" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:29246504" ; rdfs:label "VSVΔG-MERS vaccine" ; rdfs:seeAlso "VIOLIN ID: 5722" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005124 obo:IAO_0000115 "A MERS subunit vaccine made of a neutralizing monoclonal antibodiesagainst MERS-CoV which bind to the N-terminal domain (NTD) of the MERS-CoV S1 subunit that was expressed by baculovirus-insect cell sf9-derived recombinant MERS-CoV." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5724" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:28536429" ; rdfs:label "MERS rNTD vaccine" ; rdfs:seeAlso "VIOLIN ID: 5724" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005125 obo:IAO_0000115 "A SARS inactivated vaccine made from inactivated whole virus by formalin and Ultraviolet radiation, hence Double Inactivated (DI) Vaccine" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5742" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:22536382" ; rdfs:label "inactivated whole (formalin and UV radiation) SARS-CoV vaccine" ; rdfs:seeAlso "VIOLIN ID: 5742" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0005126 obo:IAO_0000115 "A recombinant SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5743" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:22536382" ; rdfs:label "recombinant SARS DNA spike protein vaccine" ; rdfs:seeAlso "VIOLIN ID: 5743" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ] . obo:VO_0005127 obo:IAO_0000115 "A SARS VLP vaccine made from the SARS-CoV spike protein (S) and the Nucleocapsid (N), envelope (E) and membrane (M) proteins from mouse hepatitis coronavirus (MHV)" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5747" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:22536382" ; rdfs:label "Viral-like-particle S-MHV SARS vaccine" ; rdfs:seeAlso "VIOLIN ID: 5747" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005128 obo:IAO_0000115 "A SARS inactivated vaccine made from SARS-CoV inactivated by ultraviolet radiation and a Toll-Like Receptor Agonist Adjuvant is added to prevent eosinophilic immunopathology" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5741" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:22536382" ; rdfs:label "UV-Inactivated SARS + TLR agonist vaccine" ; rdfs:seeAlso "VIOLIN ID: 5741" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0005129 obo:IAO_0000115 "A SARS inactivated vaccine made from SARS-CoV inactivated by ultraviolet radiation" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5740" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:22536382" ; rdfs:label "UV-Inactivated SARS vaccine" ; rdfs:seeAlso "VIOLIN ID: 5740" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0005130 obo:IAO_0000115 "A MERS recombinant vector made from Venezuelan equine encephalitis replicons bearing epitopes of N protein from MERS. Crosslisted as SARS vaccine (VIOLINID:5754). Efficacy higher intranasally than subcutaneously." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5748" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:26954467" ; rdfs:label "VRP-MERS-N vaccine" ; rdfs:seeAlso "VIOLIN ID: 5748" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005131 obo:IAO_0000115 "A SARS recombinant vector vaccine made from Venezuelan equine encephalitis replicons (VRP) encoding a SARS-CoV CD4+ T cell epitope vaccinated intranasally. Crosslisted as MERS vaccine (VIOLINID:5789). Efficacy higher intranasally than subcutaneously." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5749" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:26954467" ; rdfs:label "VRP-SARS-N vaccine" ; rdfs:seeAlso "VIOLIN ID: 5749" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005132 obo:IAO_0000115 "A MERS DNA vaccine made of plasmid vaccines that encoded S1 subunit only" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5750" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:26954467" ; rdfs:label "rVV-SARS vaccine" ; rdfs:seeAlso "VIOLIN ID: 5750" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005133 obo:IAO_0000115 "A MERS recombinant vector vaccine made of live-attenuated measles virus (MV) vaccine encoding the MERS-CoV spike protein (MERS-S)." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5757" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:26355094" ; rdfs:label "MVvac2-MERS-S(H) vaccine" ; rdfs:seeAlso "VIOLIN ID: 5757" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005134 obo:IAO_0000115 "A MERS recombinant vector vaccine made of live-attenuated measles virus (MV) vaccine encoding the MERS-CoV nucleocapsid protein (MERS-N)." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5760" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:29902727" ; rdfs:label "MVvac2-MERS-N vaccine" ; rdfs:seeAlso "VIOLIN ID: 5760" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005135 obo:IAO_0000115 "A MERS recombinant vector made of Chimpanzee adenovirus Oxford 1 vector expressing S protein from MERS-CoV‚Äô" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5751" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:29263883" ; rdfs:label "ChAdOx1-MERS-S vaccine" ; rdfs:seeAlso "VIOLIN ID: 5751" ; rdfs:subClassOf obo:VO_0004900, [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005181 ] . obo:VO_0005136 obo:IAO_0000115 "A MERS recombinant vector made of Adenovirus type 41 used as vector for MERS-CoV S protein.‚Äô" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5760" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:25762305" ; rdfs:label "Ad41.MERS vaccine" ; rdfs:seeAlso "VIOLIN ID: 5760" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005137 obo:IAO_0000115 "A MERS VLP vaccine made from a recombinant baculovirus co-expresssing the spike S, envelope (E), and membrane (M) proteins of MERS." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5758" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:23986586" ; rdfs:label "MVA-MERS vaccine" ; rdfs:seeAlso "VIOLIN ID: 5758" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005138 obo:IAO_0000115 "A SARS DNA vaccine made from encoding calrectulin linked to a SARS-CoV N protein" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5753" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:15078946" ; rdfs:label "CRT-N SARS vaccine" ; rdfs:seeAlso "VIOLIN ID: 5753" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005139 obo:IAO_0000115 "A SARS recombinant vector vaccine made from a line attenuated and recombinant SARS-CoV lacking the E gene" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=3155" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:18463152" ; rdfs:label "rSARS-CoV-ŒîE vaccine" ; rdfs:seeAlso "VIOLIN ID: 3155" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005140 obo:IAO_0000115 "A MERS recombinant vector made of MVvac2 (measle virus) expressing a soluble, truncated version of spike glycoprotein of MERS-CoV in its full length cloned into the MVvac2 genome and rescued." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5759" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:26355094" ; rdfs:label "MVvac2-MERS-solS vaccine" ; rdfs:seeAlso "VIOLIN ID: 5759" ; rdfs:subClassOf obo:VO_0004900 . obo:VO_0005141 obo:IAO_0000115 "A SARS-CoV-2 whole virus vaccine made from a purified inactivated SARS-CoV-2 virus." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang, Rohit Goru, Oliver He" ; obo:IAO_0000118 "PiCoVacc" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5761", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php", "https://en.wikipedia.org/wiki/CoronaVac" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:32376603" ; rdfs:label "CoronaVac" ; rdfs:seeAlso "VIOLIN ID: 5761" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_314146 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005142 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine composed of the SARS-CoV-2 S protein receptor-binding domain produced in Chinese hamster ovary (CHO) cells and adjuvant aluminum hydroxide." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5764", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ZF2001" ; rdfs:seeAlso "VIOLIN ID: 5764" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005143 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine made of self-coding RNA encoding SARS-CoV-2 spike protein encapsulated within a lipid nanoparticle." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5771" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:32647131" ; rdfs:label "LNP-nCoVsaRNA" ; rdfs:seeAlso "VIOLIN ID: 5771" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000728 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005179 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005144 obo:IAO_0000115 "A SARS-CoV-2 vaccine made from a recombinant adinvorius type-5 expressing SARS-CoV-2 S protein." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5768", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:32450106" ; rdfs:label "Ad5-nCoV" ; rdfs:seeAlso "VIOLIN ID: 5768" ; rdfs:subClassOf obo:VO_0005268, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0001081 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005145 obo:IAO_0000115 "A MERS DNA Vaccine that is made of the plasmid pGX9109 expressing MERS S protein." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5769" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:32450106" ; rdfs:label "MERS GLS-5300 vaccine" ; rdfs:seeAlso "VIOLIN ID: 5769" ; rdfs:subClassOf obo:VO_0004900, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_314146 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1335626 ] . obo:VO_0005146 obo:IAO_0000115 "A SARS DNA vaccine made of a single closed plasmid DNA marcromolecule (VRC-8138) that produces a deletion mutant of the SARS Spike glycoprotein" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5770" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:18824060" ; rdfs:label "VRC-SRSDNA015-00-VP vaccine" ; rdfs:seeAlso "VIOLIN ID: 5770" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005147 obo:IAO_0000115 "A SARS-CoV recombinant vector vaccine that is made from the Newcastle disease virus from the mesogenic Beaudette C strainexpressing SARS-CoV S protein." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5766" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:17535926" ; rdfs:label "SARS NDV-BC/S vaccine" ; rdfs:seeAlso "VIOLIN ID: 5766" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9534 ] . obo:VO_0005148 obo:IAO_0000115 "A SARS-CoV recombinant vector vaccine that is made from the Newcastle disease virus from the lentogenic LaSota strain expressing SARS-CoV S protein." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5767" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:17535926" ; rdfs:label "SARS NDV-VF/S vaccine" ; rdfs:seeAlso "VIOLIN ID: 5767" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9534 ] . obo:VO_0005149 obo:IAO_0000115 "A SARS DNA vaccine made from rDNA-expressed ectodomain of the S protein." ; obo:IAO_0000116 "JZ: may be same as VO:0005126" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5745" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:16497416" ; rdfs:label "rDNA-expressed S SARS protein vaccine" ; rdfs:seeAlso "VIOLIN ID: 5745" ; rdfs:subClassOf obo:VO_0012183 . obo:VO_0005150 obo:IAO_0000115 "A SARS DNA vaccine made up of arecombinat vector vaccine made from recombinant measles virus expressing S protein and recombinant measles virus expressing N protein." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5762" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:18346823" ; rdfs:label "rMV-S + rMV-N vaccine" ; rdfs:seeAlso "VIOLIN ID: 5762" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_5762 ] . obo:VO_0005151 obo:IAO_0000115 "A SARS-CoV recombinant vector made from a baculovirus vector expressing SARS-CoV S protein." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5763" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:22536382" ; rdfs:label "SARS-CoV Baculovirus S protein Vaccine" ; rdfs:seeAlso "VIOLIN ID: 5763" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_5763 ] . obo:VO_0005152 obo:IAO_0000115 "A MERS recombinant vector made of recombinant modified vaccinia virus Ankara (rMVA) vaccine vector carrying full MERS-CoV spike glycoprotein." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "VIOLIN: http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=5752" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "PubMed ID:32325037" ; rdfs:label "MVA-MERS-S vaccine" ; rdfs:seeAlso "VIOLIN ID: 5752" ; rdfs:subClassOf obo:VO_0004900, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005153 obo:IAO_0000115 "A SARS-CoV-2 single dose intranasal vaccine manufactured by Altimmune in collaboration with the University of Alabama-Birmingham. This vaccine was discontinued after a Phase 1 trial." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://altimmune.com/adcovid/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AdCOVID" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005154 obo:IAO_0000115 "A plasmid pCI-N, encoding the full-length N gene of SARS-CoV, was constructed and expressed in Escherichia coli DH5alpha" ; obo:IAO_0000119 "[PubMed: 15582659]" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-CoV pCI-N DNA vaccine" ; rdfs:seeAlso "VIOLIN ID: 5735" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0005155 obo:IAO_0000115 "A SARS-CoV 2 (rSARS-CoV-2) subunit vaccine made of nanoparticles composed of a trimeric full-length SARS-CoV-2 spike glycoprotein and Matrix-M1 adjuvant." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000118 "Covovax" ; obo:IAO_0000119 "PubMed:32376603" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NVX-CoV2373" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_314146 ] . obo:VO_0005156 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine that has a lipid nanoparticle (LNP) platform and Spike protein antigen" ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "NCT04758962" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CoV2 SAM" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005157 obo:IAO_0000115 "A SARS-CoV2 RNA vaccine made of lipid nanoparticle with mRNA which encodes the S-2P antigen, made of the SARS-CoV-2 glycoprotein with a transmembrane anchor and intact S1-S2 cleavage site." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang, Rohit Goru, Oliver He" ; obo:IAO_0000118 "COVID-19 Vaccine Moderna", "CX-024414", "mRNA-1273" ; obo:IAO_0000119 "PubMed:32663912", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php", "https://en.wikipedia.org/wiki/MRNA-1273", "https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/Moderna.html", "https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/moderna-covid-19-vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Moderna COVID-19 vaccine" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005179 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005158 obo:IAO_0000115 "A SARS-CoV2 recombinat vector vaccine made of a chimpanzee adenovirus-vectored vaccine expressing the SARS-CoV-2 spike protein" ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000118 "AZD1222", "COVID-19 Vaccine AstraZeneca", "ChAdOx1 nCoV-19" ; obo:IAO_0000119 "PubMed:32702298", "https://en.wikipedia.org/wiki/AZD1222" ; obo:VO_0003099 "Covishield" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Oxford-AstraZeneca COVID-19 vaccine" ; rdfs:seeAlso "violinID:2020-001072-15, 2020-001228-32, ISRCTN89951424" ; rdfs:subClassOf obo:VO_0005268, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005181 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005159 obo:IAO_0000115 "A SARS-CoV-2 recombinant viral vector vaccine composed of Ad26 vector expressing S protein." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang, Oliver He" ; obo:IAO_0000118 "Ad26COVS1", "JNJ-78436735", "Johnson & Johnson COVID-19 vaccine" ; obo:IAO_0000119 "PubMed:32731257", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ad26.COV2.S" ; rdfs:subClassOf obo:VO_0005268, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0005178 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9526 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004932 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0005160 obo:IAO_0000115 "A SARS-CoV-2 inactivated whole virus vaccine that is developed by the Wuhan Institute of Biological Products." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "PubMed:32789505", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "WIBP-CorV" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005161 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine made of lipid nanoparticle-encapsulated mRNA (mRNA-LNP) encoding the receptor binding domain (RBD) of SARS-CoV-2 manufactured by Academy of Military Science (AMS), Walvax Biotechnology, and Suzhou Abogen Biosciences." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "PubMed:32795413" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ARCoV" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005179 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005162 obo:IAO_0000115 "A SARS-CoV-2 plasmid DNA vaccine that encodes the envelope protein." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "PubMed:32800805" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ZyCoV-D" ; rdfs:subClassOf obo:VO_0005323, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC4 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005163 obo:IAO_0000115 "A SARS-CoV-2 recombinant viral vector vaccine composed of Ad26 and Ad5 vectors expressing S protein that lyophilised." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang, Rohit Goru, Oliver He" ; obo:IAO_0000119 "PubMed:32896291", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php", "https://en.wikipedia.org/wiki/Gam-COVID-Vac" ; obo:VO_0003158 "Gam-COVID-Vac" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Sputnik V" ; rdfs:subClassOf obo:VO_0005268, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:VO_0001081 obo:VO_0005178 ) ] ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005164 obo:IAO_0000115 "A SARS-CoV-2 investigational vaccine comprising a self-replicating (replicon) mRNA that encodes for the prefusion spike protein of 2019-nCoV formulated in a lipid nanoparticle" ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "PubMed:32973505" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ARCT-021" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005179 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005165 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine developed by AnGes, named as AG0301-COVID19." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "NCT04463472" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AG0301-COVID19" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005166 obo:IAO_0000115 "A SARS-CoV-2 inactivated whole virus vaccine that produced in Vero cells that is developed by the Beijing Institute of Biological Products." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "ChiCTR2000032459, ChiCTR2000034780", "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php", "https://en.wikipedia.org/wiki/BBIBP-CorV", "https://go.drugbank.com/drugs/DB15807" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BBIBP-CorV" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005167 obo:IAO_0000115 "A SARS-CoV-2 inactivated whole virus vaccine that is developed by the Chinese Academy of Medical Sciences ." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000118 "IMBCAMS COVID-19 vaccine" ; obo:IAO_0000119 "PubMed:32376603" ; obo:VO_0003099 "Covidful" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chinese Academy of Medical Sciences COVID-19 vaccine" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005168 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine developed by CureVac AG and CEPI." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "NCT04449276" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVnCoV" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005169 obo:IAO_0000115 "A SARS-CoV 2 recombinant viral vector using Gorilla Adenovirus that encodes for SARS-CoV-2 Spike protein." ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "https://www.covidx.eu/grad-cov2" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GRAd-COV2" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:VO_0005177 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005170 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine expressing the SARS-CoV-2 S protein" ; obo:IAO_0000117 "Anthony Huffman, Philip Huang" ; obo:IAO_0000119 "NCT04445389" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GX-19" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005171 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine that is made of a protein subunit made of the RBD domain of the S protein." ; obo:IAO_0000117 "Anthony Huffman", "Philip Huang" ; obo:IAO_0000119 "PMID:32973505" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "KBP-COVID-19" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005172 obo:IAO_0000115 "A DNA vaccine that expresses S protein from the pGX9501 vector" ; obo:IAO_0000117 "Anthony Huffman", "Philip Huang" ; obo:IAO_0000119 "PMID:32433465" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "INO-4800" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005173 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine developed by Adimmune Corporation. AdimrSC-2f is a candidate vaccine against COVID-19 developed by Adimmune Corporation (Adimmune). Using the baculovirus-insect cells expression system, the recombinant receptor binding domain (RBD) of SARS-CoV-2 spike (S) protein is amplified and purified. AdimrSC-2f is formulated in the different dosages of Spike (S) protein without/with aluminum content as adjuvant." ; obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000119 "NCT04522089", "https://go.drugbank.com/drugs/DB16436", "https://www.smartpatients.com/trials/NCT04522089" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AdimrSC-2f" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005174 obo:IAO_0000115 "A SARS-CoV-2 oral DNA vaccine that delivers plasmids containing synthetic DNA encoding spike protein from SARS-CoV-2." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04334980", "https://www.symvivo.com/covid-19" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bacTRL-Spike" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000886 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004969 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0005175 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine manufactured by Chulalongkorn University" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04566276" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ChulaCov19" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004970 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0005176 obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "A synthetic modified vaccinia Ankara (MVA)-based SARS-CoV-2 vaccine." ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0005394 ; a owl:Class ; rdfs:label "obsolete COH04S1" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0005177 obo:IAO_0000115 "an adenovirus vaccine vector that uses a gorilla adenovirus." ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "gorilla adenovirus vector" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0005178 obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "adenovirus serotype 26 vaccine vector" ; rdfs:seeAlso "NCBI Taxonomy ID: 46928" ; rdfs:subClassOf obo:VO_0000136 . obo:VO_0005179 obo:IAO_0000115 "A nanoparticle vector composed of lipids." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "PMID: 20402623" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "lipid nanoparticle vector" ; rdfs:subClassOf obo:VO_0005180 . obo:VO_0005180 obo:IAO_0000115 "A vaccine component composed of a synthetic component that is solid and spherical structures ranging to around 100 nm in size and prepared from natural or synthetic polymers." ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000119 "PMID: 22353619" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "nanoparticle vector" ; rdfs:subClassOf obo:VO_0000179 . obo:VO_0005181 obo:IAO_0000115 "A chimpanzee adenovirus vaccine vector that patented by Oxford and derived from ChAd serotype Y25 that exchanges the native E4 orf4, orf6 and orf6/7 genes for those from HAdV-C5" ; obo:IAO_0000119 "PMID: 29527232" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "chimpanzee adenovirus Oxford1 vaccine vector" ; rdfs:seeAlso "ChAdOx1" ; rdfs:subClassOf obo:VO_0001055 . obo:VO_0005182 obo:IAO_0000115 "A chimpanzee adenovirus vaccine vector developed by Oxford by deleting E1/E3 from ChAd68 with a modified E4 region." ; obo:IAO_0000119 "PMID: 29527232" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "chimpanzee adenovirus Oxford2 vaccine vector" ; rdfs:seeAlso "ChAdOx2" ; rdfs:subClassOf obo:VO_0001055 . obo:VO_0005183 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine developed by Providence Health & Services." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04627675" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CORVax12" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005184 obo:IAO_0000115 "A SARS-CoV-2 recombinant vector vaccine employing the lentiviral vector system and developed by Shenzhen Geno-Immune Medical Institute." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04299724" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 aAPC vaccine" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005185 obo:IAO_0000115 "A SARS-CoV-2 refrigerator-stable mRNA vaccine by Moderna that encodes for the portions of the SARS-CoV-2 spike protein critical for neutralization, specifically the Receptor Binding Domain (RBD) and N-terminal Domain (NTD)" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04813796", "https://investors.modernatx.com/news-releases/news-release-details/first-participants-dosed-phase-1-study-evaluating-mrna-1283" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "mRNA-1283" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005186 obo:IAO_0000115 "A prophylactic plasmid DNA Vaccine for SARS CoV-2 by Entos Pharmaceuticals" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04591184" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Covigenix VAX-001" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005187 obo:IAO_0000115 "A SARS-CoV-2 live, attenuated vaccine manufactured by Codagenix, Inc." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04619628" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVI-VAC" ; rdfs:subClassOf obo:VO_0005204, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005188 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine developed by Health Institutes of Turkey" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "ERUCOV-VAC" ; obo:IAO_0000119 "NCT04691947" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Turkovac" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005189 obo:IAO_0000115 "A SARS-CoV-2 human adenovirus serotype 5 (hAd5) vector vaccine with E1/E2b/E3 deletions expressing SARS-CoV-2 viral antigen spike fusion protein and nucleocapsid with an enhanced T-cell stimulation domain." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04591717" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hAd5-COVID-19" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000886 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005190 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine developed by University Hospital Tuebingen" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04546841" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IMP CoVac-1" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005191 obo:IAO_0000115 "A SARS-CoV-2 recombinant vector vaccine that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein (S)" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04569383" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA-SARS-2-S" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005192 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine that contains the Spike (S) protein with CpG 1018 and aluminum content as adjuvant." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04487210" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVC-COV1901" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003153 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0004978 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0005193 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine developed by Vaxine Pty Ltd and CinnaGen Co. and adjuvanted with Advax" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000118 "SpikoGen" ; obo:IAO_0000119 "NCT04453852" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVAX-19" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005194 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine with the S1 component of the SARS-CoV-2 spike (S) protein and SWE adjuvant." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04702178" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVAC" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005195 obo:IAO_0000115 "A SARS-CoV-2 vaccine that uses a recombinant vesicular stomatitis virus (rVSV) platform, and is made by Merck. Development of the vaccine was discontinued on January 25, 2021." ; obo:IAO_0000117 "Philip Huang, Oliver He" ; obo:IAO_0000119 "https://www.merck.com/news/merck-discontinues-development-of-sars-cov-2-covid-19-vaccine-candidates-continues-development-of-two-investigational-therapeutic-candidates/" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V590" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005196 obo:IAO_0000115 "A SARS-CoV-2 adenoviral vector-based oral vaccine by Vaxart expressing a SARS-CoV-2 antigen and dsRNA adjuvant" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04563702" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VXA-CoV2-1" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000886 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005197 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by SK Bioscience Co., Ltd., and equipped with an aluminum hydroxide adjuvant" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04750343" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SKYCovione" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005198 obo:IAO_0000117 "Philip Huang, Rohit Goru, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 RNA vaccine" ; rdfs:subClassOf obo:VO_0000186, obo:VO_0004908, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000728 ] . obo:VO_0005199 obo:IAO_0000117 "Philip Huang, Rohit Goru, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 recombinant vector vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0004908 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000484 obo:VO_0004908 ) ] . obo:VO_0005200 obo:IAO_0000117 "Philip Huang, Rohit Goru, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 recombinant adenoviral vector vaccine" ; rdfs:subClassOf obo:VO_0005199 . obo:VO_0005201 obo:IAO_0000117 "Philip Huang, Rohit Goru, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 inactivated vaccine" ; rdfs:subClassOf obo:VO_0004908 . obo:VO_0005202 obo:IAO_0000117 "Philip Huang" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 subunit vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0004908, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ] . obo:VO_0005203 obo:IAO_0000117 "Philip Huang" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 DNA vaccine" ; rdfs:subClassOf obo:VO_0004908 . obo:VO_0005204 obo:IAO_0000117 "Philip Huang" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 live, attenuated vaccine" ; rdfs:subClassOf obo:VO_0004908 . obo:VO_0005205 obo:IAO_0000117 "Philip Huang" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 virus-like particle vaccine" ; rdfs:subClassOf obo:VO_0004908 . obo:VO_0005206 obo:IAO_0000115 "A saponin vaccine adjuvant comprised of 40 nm nanoparticles composed of Quillaja saponins, cholesterol and phospholipid." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "PMID:22844480" ; a owl:Class ; rdfs:label "Matrix-M vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001267 . obo:VO_0005207 obo:IAO_0000115 "A carbohydrate vaccine adjuvant derived from delta inulin" ; obo:IAO_0000116 """Chemical Nature: Carbohydrate Mechanism of Action: Complement, Dendritic cells (unknown receptor), Other, Unknown Immune profile induced: mixed Th1/Th2 By routes: IM, IN, IP, SQ, inhalation, Point of Contact: Nikolai Petrovsky, Vaxine https://www.ncbi.nlm.nih.gov/pubmed/?term=31009889 https://www.ncbi.nlm.nih.gov/pubmed/?term=25520500 https://www.ncbi.nlm.nih.gov/pubmed/?term=28758637 https://www.ncbi.nlm.nih.gov/pubmed/?term=23864620 https://www.ncbi.nlm.nih.gov/pubmed/?term=24342245 https://www.ncbi.nlm.nih.gov/pubmed/?term=23306367 https://www.ncbi.nlm.nih.gov/pubmed/?term=21147758 https://www.ncbi.nlm.nih.gov/pubmed/?term=15479440 https://www.ncbi.nlm.nih.gov/pubmed/?term=26031451 https://www.ncbi.nlm.nih.gov/pubmed/?term=25659269 https://www.ncbi.nlm.nih.gov/pubmed/?term=33883559 https://www.ncbi.nlm.nih.gov/pubmed/?term=30312742 https://www.ncbi.nlm.nih.gov/pubmed/?term=21736913 https://www.ncbi.nlm.nih.gov/pubmed/?term=30218687 https://www.ncbi.nlm.nih.gov/pubmed/?term=25459531 https://www.ncbi.nlm.nih.gov/pubmed/?term=24958701 https://www.ncbi.nlm.nih.gov/pubmed/?term=25516480 https://www.ncbi.nlm.nih.gov/pubmed/?term=20130134 https://www.ncbi.nlm.nih.gov/pubmed/?term=23388724 https://www.ncbi.nlm.nih.gov/pubmed/?term=21169215 https://www.ncbi.nlm.nih.gov/pubmed/?term=30832356 https://www.ncbi.nlm.nih.gov/pubmed/?term=30322015 https://www.ncbi.nlm.nih.gov/pubmed/?term=28602608 https://www.ncbi.nlm.nih.gov/pubmed/?term=28676380 https://www.ncbi.nlm.nih.gov/pubmed/?term=33542494 https://www.ncbi.nlm.nih.gov/pubmed/?term=26232344 https://www.ncbi.nlm.nih.gov/pubmed/?term=22728225 https://www.ncbi.nlm.nih.gov/pubmed/?term=22728225 https://www.ncbi.nlm.nih.gov/pubmed/?term=25267153 https://www.ncbi.nlm.nih.gov/pubmed/?term=31300280 https://www.ncbi.nlm.nih.gov/pubmed/?term=28301280 https://www.ncbi.nlm.nih.gov/pubmed/?term=22717330 https://www.ncbi.nlm.nih.gov/pubmed/?term=26177480 https://www.ncbi.nlm.nih.gov/pubmed/?term=10000000 https://www.ncbi.nlm.nih.gov/pubmed/?term=27342914 https://www.ncbi.nlm.nih.gov/pubmed/?term=12""" ; obo:IAO_0000117 "Nikolai Petrovsky", "Oliver He", "Philip Huang", "Wolfgang Leitner" ; obo:IAO_0000119 "PMID:22728225", "https://vac.niaid.nih.gov/view?id=37", "https://www.ncbi.nlm.nih.gov/pubmed/?term=10000000", "https://www.ncbi.nlm.nih.gov/pubmed/?term=12", "https://www.ncbi.nlm.nih.gov/pubmed/?term=15479440", "https://www.ncbi.nlm.nih.gov/pubmed/?term=20130134", "https://www.ncbi.nlm.nih.gov/pubmed/?term=21147758", "https://www.ncbi.nlm.nih.gov/pubmed/?term=21169215", "https://www.ncbi.nlm.nih.gov/pubmed/?term=21736913", "https://www.ncbi.nlm.nih.gov/pubmed/?term=22717330", "https://www.ncbi.nlm.nih.gov/pubmed/?term=22728225", "https://www.ncbi.nlm.nih.gov/pubmed/?term=23306367", "https://www.ncbi.nlm.nih.gov/pubmed/?term=23388724", "https://www.ncbi.nlm.nih.gov/pubmed/?term=23864620", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24342245", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24958701", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25267153", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25459531", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25516480", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25520500", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25659269", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26031451", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26177480", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26232344", "https://www.ncbi.nlm.nih.gov/pubmed/?term=27342914", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28301280", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28602608", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28676380", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28758637", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30218687", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30312742", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30322015", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30832356", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31009889", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31300280", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33542494", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33883559" ; obo:VO_0005328 "37" ; a owl:Class ; rdfs:label "Advax vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001359, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005208 obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://www.curevac.com/en/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "CureVac AG" . obo:VO_0005209 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Research Institute for Biological Safety Problems" . obo:VO_0005210 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Bharat Biotech International Limited" . obo:VO_0005211 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "University of Munich (Ludwig-Maximilians)" . obo:VO_0005212 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "West China Hospital" . obo:VO_0005213 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "University Hospital Tuebingen" . obo:VO_0005214 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Shenzhen Geno-Immune Medical Institute" . obo:VO_0005215 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Providence Health & Services" . obo:VO_0005216 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "City of Hope Medical Center" . obo:VO_0005217 obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://codagenix.com/" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Codagenix, Inc." . obo:VO_0005218 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Center for Genetic Engineering and Biotechnology" . obo:VO_0005219 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Biological E. Ltd" . obo:VO_0005220 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "GeneOne Life Science, Inc." . obo:VO_0005221 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Nanogen Pharmaceutical Biotechnology" . obo:VO_0005222 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Shionogi" . obo:VO_0005223 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Altimmune, Inc." . obo:VO_0005224 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Erciyes University" . obo:VO_0005225 obo:IAO_0000117 "Philip Huang" ; a obo:VO_0000299, owl:NamedIndividual ; rdfs:label "Vaccine and Infectious Disease Organization" . obo:VO_0005226 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by the Razi Vaccine and Serum Research Institute with a Spike protein antigen" ; obo:IAO_0000117 "Philip Huang" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Razi Cov Pars" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005227 obo:IAO_0000115 "A SARS-CoV-2 recombinant adenoviral vector vaccine that is manufactured by Bharat Biotech International Ltd. and administered intranasally" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04751682" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "BBV154" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005228 obo:IAO_0000115 "A SARS-CoV-2 Chimpanzee Adenovirus serotype 6 vector vaccine manufactured by Gritstone Oncology and the National Institute of Allergy and Infectious Diseases" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04776317" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ChAdV68-S" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005229 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine by Shifa Pharmed" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.irct.ir/trial/52701" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVIran Barakat" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005230 obo:IAO_0000115 "A SARS-CoV-2 plasmid DNA vaccine manufactured by Takis and Rottapharm Biotech" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://www.clinicaltrialsregister.eu/ctr-search/trial/2020-003734-20/IT" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-eVax" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005231 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine manufactured by University of Sydney, Bionet Co., and Technovalia" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04742842" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVIGEN" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005232 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine by EuBiologics Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04783311" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EuCorVac-19" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005233 obo:IAO_0000115 "A SARS-CoV-2 lipid nanoparticle (LNP)-encapsulated mRNA-based vaccine that encodes for a full-length, prefusion stabilized S protein of the SARS-CoV-2 B.1.351 variant" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04785144" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "mRNA-1273.351" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005234 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine by SK Bioscience" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04760743" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NBP2001" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005235 obo:IAO_0000115 "A SARS-CoV-2 recombinant viral vector vaccine by Mahidol University" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04764422" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NDV-HXP-S" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005236 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine by Providence Therapeutics" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04765436" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PTX-COVID19-B" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005237 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by Walter Reed Army Institute of Research" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04784767" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SpFN" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005238 obo:IAO_0000115 "A SARS-CoV-2 virus-like particle vaccine that expresses a modified version of the SARS-CoV-2 spike (S) glycoprotein and is equipped with an aluminum phosphate adjuvant. It is manufactured by VBI Vaccines Inc. and is delivered intramuscularly." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04773665" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VBI-2902a" ; rdfs:subClassOf obo:VO_0005205, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005239 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine developed by Organization of Defensive Innovation and Research in Iran" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.irct.ir/trial/54133" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "FAKHRAVAC" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005240 obo:IAO_0000115 "A SARS-CoV-2 live, attenuated vaccine manufactured by Meissa Vaccines, Inc. that expresses the spike (S) protein of SARS-CoV-2." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04798001" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MV-014-212" ; rdfs:subClassOf obo:VO_0005204, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005241 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine that is manufactured by Sanofi Pasteur" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04798027" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MRT5500" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005242 obo:IAO_0000115 "An object property that represents a relation between a material entity and biological process" ; obo:IAO_0000117 "Anthony Huffman", "Oliver He" ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000040 ; rdfs:label "up-expressed as immune signature of" ; rdfs:range obo:BFO_0000015 . obo:VO_0005243 obo:IAO_0000115 "A SARS-CoV-2 inactivated whole virus vaccine developed by the Chumakov Centre at the Russian Academy of Sciences" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CoviVac" ; rdfs:subClassOf obo:VO_0005266, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005244 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by Instituto Finlay de Vacunas. It is used as a booster dose for the Soberana 02 COVID-19 vaccine" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://rpcec.sld.cu/trials/RPCEC00000366-En" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Soberana Plus" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005245 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine manufactured by Daiichi Sankyo Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:VO_0003159 "Daiichi Sankyo Co., Ltd." ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DS-5670a" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005246 obo:IAO_0000115 "A SARS-CoV-2 recombinant Newcastle Disease Virus vector vaccine expressing membrane-anchored pre-fusion-stabilized trimeric SARS-CoV-2 S protein" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04830800" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVIVAC" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0001060 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005247 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine developed by Livzon Mabpharm Inc." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "ChiCTR2100045107" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V-01" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005248 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine developed by the National Vaccine and Serum Institute of China" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04869592" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 subunit vaccine by National Vaccine and Serum Institute of China" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005249 obo:IAO_0000115 "A SARS-COV-2 temperature-sensitive self-replicating RNA vaccine expressing the receptor binding domain of the SARS-CoV-2 spike protein." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04863131" ; obo:VO_0003159 "Elixirgen Therapeutics, Inc." ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EXG-5003" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005250 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine developed by KM Biologics Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "jRCT2071200106" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "KD-414" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005251 obo:IAO_0000115 "A COVID-19 virus-like particle vaccine developed by the Scientific and Technological Research Council of Turkey" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04818281" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey" ; rdfs:subClassOf obo:VO_0005205, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005252 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by Jiangsu Rec-Biotechnology Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04818801" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ReCOV" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005253 obo:IAO_0000115 "A SARS-CoV-2 inactivated virus vaccine by Kocak Farma" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04838080" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ko√ßak-19 Inaktif Adjuvanlƒ± COVID-19 Vaccine" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005254 obo:IAO_0000115 "A SARS-CoV-2 recombinant adenoviral vector vaccine by Tetherex Pharmaceutical Corporation" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04839042" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SC-Ad6-1" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005255 obo:IAO_0000115 "A COVID-19 virus-like particle vaccine developed by Radboud University" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04839146" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ABNCoV2" ; rdfs:subClassOf obo:VO_0005205, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005256 obo:IAO_0000115 "A SARS-CoV-2 Lipid-Inorganic Nanoparticle (LION‚Ñ¢) formulated replicating mRNA vaccine that encodes for a full-length spike (S) protein of the SARS-CoV-2 virus" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04844268" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HDT-301" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005257 obo:IAO_0000115 "A SARS-CoV-2 inactivated virus vaccine by the Scientific and Technological Research Council of Turkey adjuvanted by aluminum hydroxide and CpG ODN" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04866069" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 inactivated vaccine by the Scientific and Technological Research Council of Turkey" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005258 obo:IAO_0000115 "An MF59-adjuvanted SARS-CoV-2 subunit vaccine based on recombinant SARS-CoV-2 spike glycoprotein stabilised in a pre-fusion conformation by a novel molecular clamp (spike glycoprotein-clamp [sclamp])" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "PubMed ID: 33887208" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MF59-adjuvanted SARS-CoV-2 Sclamp vaccine" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005259 obo:IAO_0000115 "A recombinant Newcastle Disease Virus vectored vaccine for SARS-CoV-2 by Laboratorio Avi-Mex" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04871737" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 rNDV vector vaccine by Laboratorio Avi-Mex" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005260 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "ChiCTR2100045984" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005261 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by OSE Immunotherapeutics" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04885361" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CoVepiT" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005262 obo:IAO_0000115 "A SARS-CoV-2 recombinant viral vector vaccine by the German Center for Infection Research" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04895449" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MVA-SARS-2-ST" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0001107 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005263 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine that is orally administered and manufactured by Syneos Health" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04893512" ; obo:VO_0003159 "Syneos Health" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CoV2-OGEN1" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000886 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005264 obo:IAO_0000115 "A COVID-19 vaccine that is authorized for emergent use, which is typically authorized based on an Emergency Use Authorization (EUA)." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php", "https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/covid-19-vaccines" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "authorized COVID-19 vaccine" ; rdfs:subClassOf obo:VO_0004908 . obo:VO_0005265 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "authorized COVID-19 RNA vaccine" ; rdfs:subClassOf obo:VO_0005198, obo:VO_0005264 . obo:VO_0005266 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "authorized inactivated COVID-19 vaccine" ; rdfs:subClassOf obo:VO_0005201, obo:VO_0005264 . obo:VO_0005267 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "authorized COVID-19 recombinant vector vaccine" ; rdfs:subClassOf obo:VO_0005199, obo:VO_0005264 . obo:VO_0005268 obo:IAO_0000117 "Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "authorized COVID-19 recombinant adenoviral vector vaccine" ; rdfs:subClassOf obo:VO_0005200, obo:VO_0005267 . obo:VO_0005269 obo:IAO_0000117 "Oliver He, Philip Huang" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "authorized COVID-19 subunit vaccine" ; rdfs:subClassOf obo:VO_0005202, obo:VO_0005264 . obo:VO_0005270 obo:IAO_0000115 "A vaccine adjuvant that includes IV270, which is a low‚Äìmolecular weight TLR7 agonist conjugated to a phospholipid and is a highly potent and stable immune activator." ; obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: TLR7 Mechanism of Action: Activation of innate immune pathways Immune profile induced: Th1-biased Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces CD8 T cells, (3) Induces epitope spreading, (4) Provides innate protection, (5) Promotes antibody affinity maturation, (6) Promotes antibody epitope spreading By routes: intramuscular and intranasal. Point of Contact: Dennis Carson, UCSD""" ; obo:IAO_0000117 "Dennis Carson", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "1V270" ; obo:IAO_0000119 "PMID:25568203", "PMID:28724768", "PMID:32636840/", "https://vac.niaid.nih.gov/view?id=6" ; obo:VO_0005328 "6" ; a owl:Class ; rdfs:label "1V270 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005272 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005271 obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: TLR4 Mechanism of Action: Innate immune activation Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: (1) Induces mucosal immunity, (2) Anti-inflammatory, (3) Promotes antibody epitope spreading. By routes: intramuscular and intranasal. Point of Contact: Dennis Carson, UCSD""" ; obo:IAO_0000117 "Amogh Madireddi", "Dennis Carson", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "2B182C" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=7", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25568203", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28724768", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32636840" ; obo:VO_0005328 "7" ; a owl:Class ; rdfs:label "2B182C vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005272 obo:IAO_0000115 "A role of a material entity that binds to TLR7 and activates the receptor for pathogen recognition and activation of innate immunity." ; obo:IAO_0000116 "TLR7 agonist role" ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000118 "Toll-like receptor 7 agonist role" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/TLR7" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "TLR7 receptor role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005273 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by the Research Institute for Biological Safety Problems in Kazakhstan" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04930003" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "QazCoVac-P" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005274 obo:IAO_0000119 "https://en.wikipedia.org/wiki/T_helper_cell" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "Th1 immunity stimulatory role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005275 obo:IAO_0000119 "https://en.wikipedia.org/wiki/T_helper_cell" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "Th2 immunity stimulatory role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005276 obo:IAO_0000115 "A SARS-CoV-2 self-amplifying RNA vaccine sponsored by MRC/UVRI and LSHTM Uganda Research Unit" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04934111" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LNP-nCOV saRNA-02" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005179 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005277 obo:IAO_0000115 "A multivalent SARS-CoV-2 mRNA booster vaccine which combines mRNA-1273, Moderna‚Äôs authorized vaccine against ancestral strains, and mRNA-1273.351 in a single vaccine at the 50 ¬µg dose level and lower." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://investors.modernatx.com/news-releases/news-release-details/moderna-announces-it-has-shipped-variant-specific-vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "mRNA-1273.211" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005179 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005278 obo:IAO_0000115 "A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5304" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/77" ; obo:VO_0001818 "5304" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "(H115D)VHL35 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005280 obo:IAO_0000115 "An NIAID compendium repository that stores vaccine adjuvants derived from their research studies." ; obo:IAO_0000117 "Oliver He, Amogh Madireddi, Wolfgang Leitner" ; obo:IAO_0000118 "VAC"@en ; obo:IAO_0000119 "https://vac.niaid.nih.gov/" ; a obo:OBI_0000245, owl:NamedIndividual ; rdfs:label "Vaccine Adjuvant Compendium" . obo:VO_0005281 obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: Dendritic cells (unknown receptor) Mechanism of Action: Innate immune activation Immune profile induced: Th1-biased Other Features/Characteristics: Other. Specify: Co-adjuvant for TLR4 ligands Point of Contact: Dennis Carson, UCSD""" ; obo:IAO_0000117 "Amogh Madireddi", "Dennis Carson", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "2E151" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=9" ; obo:VO_0005328 "9" ; a owl:Class ; rdfs:label "2E151 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005282 obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: CLR (Dectin, Mincle) Mechanism of Action: None/Unknown Immune profile induced: Th17-component Other Features/Characteristics: None Point of Contact: Kendal Ryter, U. Montana & Inimmune""" ; obo:IAO_0000117 "Amogh Madireddi", "Kendal Ryter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "UM-1098" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=27" ; a owl:Class ; rdfs:label "UM-1098 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005313 ] . obo:VO_0005283 obo:IAO_0000116 """Chemical Nature: Small molecule and Synthetic derivative of natural compound Receptor: Unknown and NLRP3 Mechanism of Action: Presumably the same as QS-21 in the absence of dose-limiting toxicity Immune profile induced: Th1-biased Other Features/Characteristics: None Point of Contact: Melissa Malhame, Adjuvance Technologies""" ; obo:IAO_0000117 "Amogh Madireddi", "Melissa Malhame", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "TQL-1055" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=36" ; a owl:Class ; rdfs:label "TQL-1055 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005284 obo:IAO_0000116 """Chemical Nature: Emulsion Receptor: TLR2 and TLR4 Mechanism of Action: Activation of mucosal and systemic immunity Immune profile induced: Th1/Th17 Other Features/Characteristics: Promotes antibody affinity maturation Point of Contact: Ali Fattom, BlueWillow Biologics""" ; obo:IAO_0000117 "Ali Fattom", "Amogh Madireddi", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "NanoVax/NE01" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=22", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31495593", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31515143" ; a owl:Class ; rdfs:label "NanoVax/NE01 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005307 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005314 ] . obo:VO_0005285 obo:IAO_0000116 """Chemical Nature: Other Receptor: TLR4 Mechanism of Action: TLR4 agonist Immune profile induced: Th1-biased Other Features/Characteristics: None/Unknown Point of Contact: Darrick Carter, PAI Life Sciences""" ; obo:IAO_0000117 "Amogh Madireddi", "Darrick Carter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "MiT4" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=16" ; a owl:Class ; rdfs:label "MiT4 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005286 obo:IAO_0000116 """Chemical Nature: (1) Natural compound, (2) Carbohydrate, (3) Combination adjuvant Receptor: CLR (Dectin, Mincle) and NAIP Mechanism of Action: Activation of Dectin-2-expressing innate immune cells; dual targeting of injection site and draining lymph node. Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: Promotes antibody epitope spreading Point of Contact: Ivan Zanoni, Boston Children's Hospital""" ; obo:IAO_0000117 "Amogh Madireddi", "Ivan Zanoni", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=14" ; a owl:Class ; rdfs:label "Mannadjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005287 obo:IAO_0000116 """Chemical Nature: Combination Adjuvant Receptor: TLR4 Mechanism of Action: TLR4 agonist plus potential inflammasome Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None/Unknown Point of Contact: Darrick Carter, PAI Life Sciences""" ; obo:IAO_0000117 "Amogh Madireddi", "Darrick Carter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "LiT4" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=20" ; a owl:Class ; rdfs:label "LiT4 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005288 obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: TLR7 and TLR8 Mechanism of Action: None/Unknown Immune profile induced: Th1-biased Other Features/Characteristics: None Point of Contact: Kendal Ryter, U. Montana & Inimmune""" ; obo:IAO_0000117 "Amogh Madireddi", "Kendal Ryter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "INI-4001" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=28" ; a owl:Class ; rdfs:label "INI-4001 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005272 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005306 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005289 obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: TLR4 Mechanism of Action: None/Unknown Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None Point of Contact: Kendal Ryter, U. Montana & Inimmune""" ; obo:IAO_0000117 "Amogh Madireddi", "Kendal Ryter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "INI-2004" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=26" ; a owl:Class ; rdfs:label "INI-2004 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005290 obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: TLR4 Mechanism of Action: None/Unknown Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None Point of Contact: Kendal Ryter, U. Montana & Inimmune""" ; obo:IAO_0000117 "Amogh Madireddi", "Kendal Ryter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "INI-2002" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=29" ; a owl:Class ; rdfs:label "INI-2002 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005291 obo:IAO_0000116 """Chemical Nature: Small molecule and Combination adjuvant Receptor: TLR4 and TLR7 Mechanism of Action: Activation of antigen presenting cells and stimulating B cell proliferation Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces CD8 T cells, (3) Induces epitope spreading, (4) Provides innate protection, (5) Promotes antibody epitope spreading. By routes: intramuscular and intranasal. Point of Contact: Dennis Carson, UCSD""" ; obo:IAO_0000117 "Amogh Madireddi", "Dennis Carson", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "Fos47" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=5", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25568203", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28724768", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32636840" ; a owl:Class ; rdfs:label "Fos47 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005272 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005292 obo:IAO_0000116 """Chemical Nature: Emulsion Receptor: TLR4 Mechanism of Action: Squalene emulsion plus TLR4 Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None Point of Contact: Darrick Carter, PAI Life Sciences""" ; obo:IAO_0000117 "Amogh Madireddi", "Darrick Carter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "EmT4" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=17" ; a owl:Class ; rdfs:label "EmT4 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005293 obo:IAO_0000116 """Chemical Nature: Emulsion Receptor: Unknown Mechanism of Action: Squalene emulsion possibly triggering inflammasome or through extracellular ATP Immune profile induced: None Other Features/Characteristics: None Point of Contact: Darrick Carter, PAI Life Sciences""" ; obo:IAO_0000117 "Amogh Madireddi", "Darrick Carter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "Em" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=18" ; a owl:Class ; rdfs:label "Em vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0005294 obo:IAO_0000116 """Chemical Nature: (1) Synthetic derivative of natural compound, (2) Nucleic acid Receptor: TLR3 Mechanism of Action: TLR3, possibly RIG-I - agonist Immune profile induced: Th1-biased Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces CD8 T cells, (3) Provides innate protection. By routes: SQ, IM. Point of Contact: Carolina Lopez, University of Washington at St Louis""" ; obo:IAO_0000117 "Amogh Madireddi", "Carolina Lopez", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "DDO", "DDO (Defective viral genome-Derived Oligonucleotide)", "Defective viral genome-Derived Oligonucleotide" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=30", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24099876", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29861183" ; a owl:Class ; rdfs:label "DDO (Defective viral genome-Derived Oligonucleotide) vaccine adjuvant" ; rdfs:subClassOf obo:VO_0006102, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005305 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005295 obo:IAO_0000116 """Chemical Nature: Synthetic derivative of natural compound Receptor: Unknown Mechanism of Action: (1) Antigen carrier, (2) Innate immune enhancer/activator Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces CD8 T cells, (3) Provides innate protection, (4) Other, (5) Promotes antibody affinity maturation, (6) High stability. By routes: IM, IN, IP, IN, ID, IVag. Specify: Safe for systemic or mucosal administration Point of Contact: Tulin Morcol, Captivate Pharma""" ; obo:IAO_0000117 "Amogh Madireddi", "Oliver He", "Tulin Morcol", "Wolfgang Leitner" ; obo:IAO_0000118 "CaPNP (CaPtivant)(TM)" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=11", "https://www.ncbi.nlm.nih.gov/pubmed/?term=11063495", "https://www.ncbi.nlm.nih.gov/pubmed/?term=12204953", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28716554", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28933657", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31591662" ; obo:VO_0005328 "11" ; a owl:Class ; rdfs:label "CaPNP (CaPtivant)(TM) vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005296 obo:IAO_0000116 """Chemical Nature: Small molecule, other Receptor: TLR4 Mechanism of Action: None Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: Other Point of Contact: Robert Ernst, University of Maryland - Baltimore""" ; obo:IAO_0000117 "Amogh Madireddi", "Oliver He", "Robert Ernst", "Wolfgang Leitner" ; obo:IAO_0000118 "BECC470b" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=32", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28487429", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29861179", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33309485" ; obo:VO_0005328 "32" ; a owl:Class ; rdfs:label "BECC470b vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005297 obo:IAO_0000116 """Chemical Nature: (1) Synthetic derivative of natural compound, (2) other Receptor: TLR4 Mechanism of Action: None Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None Point of Contact: Robert Ernst, University of Maryland-Baltimore""" ; obo:IAO_0000117 "Amogh Madireddi", "Oliver He", "Robert Ernst", "Wolfgang Leitner" ; obo:IAO_0000118 "BECC438s" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=33" ; obo:VO_0005328 "33" ; a owl:Class ; rdfs:label "BECC438s vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005298 obo:IAO_0000116 """Chemical Nature: Small molecule, other Receptor: TLR4 Mechanism of Action: None Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None Point of Contact: Robert Ernst, University of Maryland Baltimore""" ; obo:IAO_0000117 "Amogh Madireddi", "Oliver He", "Robert Ernst", "Wolfgang Leitner" ; obo:IAO_0000118 "BECC438b" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=31", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28487429", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29861179", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33309485" ; obo:VO_0005328 "31" ; a owl:Class ; rdfs:label "BECC438b vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005299 obo:IAO_0000116 """Chemical Nature: Combination adjuvant Receptor: TLR4 Mechanism of Action: TLR4 and potentially inflammasome Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None Point of Contact: Darrick Carter, PAI Life Services""" ; obo:IAO_0000117 "Amogh Madireddi", "Darrick Carter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "AlT4" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=19" ; obo:VO_0005328 "19" ; a owl:Class ; rdfs:label "AlT4 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005300 obo:IAO_0000116 """Chemical Nature: Combination adjuvant Receptor: TLR3 Mechanism of Action: TLR3 agonist plus potential inflammasome Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None Point of Contact: Darrick Carter, PAI Life Services""" ; obo:IAO_0000117 "Amogh Madireddi", "Darrick Carter", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "AlT3" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=21" ; obo:VO_0005328 "21" ; a owl:Class ; rdfs:label "AlT3 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005305 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005301 obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: (1) TLR7, (2) TLR8 Mechanism of Action: TLR7/8 dual agonist - lymph node delivery Immune profile induced: Th1-biased Other Features/Characteristics: Promotes antibody affinity maturation Point of Contact: Sunil David, Virovax""" ; obo:IAO_0000117 "Amogh Madireddi", "Oliver He", "Sunil David", "Wolfgang Leitner" ; obo:IAO_0000118 "Alhydroxiquim-II" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=12", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33521604", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33654090" ; obo:VO_0005328 "12" ; a owl:Class ; rdfs:label "Alhydroxiquim-II vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005272 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005306 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005302 obo:IAO_0000116 """Chemical Nature: (1) Synthetic derivative of natural compound, (2) Emulsion, (3) Combination adjuvant, (4) Other Receptor: TLR4 Mechanism of Action: Adjuplex enhances cross presentation to CD8 T cells and GLA stimulates TLR4 signaling Immune profile induced: Mixed Th1/Th17 Other Features/Characteristics: None Point of Contact: Marulasiddappa Suresh, UW Madison""" ; obo:IAO_0000117 "Amogh Madireddi", "Marulasiddappa Suresh", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "Adjuplex+GLA" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=15", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32984856", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33444400", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33767689" ; obo:VO_0005328 "15" ; a owl:Class ; rdfs:label "Adjuplex+GLA vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005314 ] . obo:VO_0005303 obo:IAO_0000116 """Chemical Nature: Small molecule Receptor: Dendritic cells (unknown receptor) Mechanism of Action: Innate immune activation/enhancer Immune profile induced: Mixed Th1/Th2 Other Features/Characteristics: None Point of Contact: Dennis Carson, UCSD""" ; obo:IAO_0000117 "Amogh Madireddi", "Dennis Carson", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "2F52" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=8", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29751735" ; obo:VO_0005328 "8" ; a owl:Class ; rdfs:label "2F52 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005304 obo:IAO_0000115 "A role of a material entity that binds to TLR4 and activates the receptor for pathogen recognition and activation of innate immunity." ; obo:IAO_0000116 "TLR4 agonist role" ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000118 "Toll-like receptor 4 agonist role" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/TLR4" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "TLR4 receptor role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005305 obo:IAO_0000115 "A role of a material entity that binds to TLR3 and activates the receptor for pathogen recognition and activation of innate immunity." ; obo:IAO_0000116 "TLR3 agonist role" ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000118 "Toll-like receptor 3 agonist role" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/TLR3" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "TLR3 receptor role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005306 obo:IAO_0000115 "A role of a material entity that binds to TLR8 and activates the receptor for pathogen recognition and activation of innate immunity." ; obo:IAO_0000116 "TLR8 agonist role" ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000118 "Toll-like receptor 8 agonist role" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/TLR8" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "TLR8 receptor role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005307 obo:IAO_0000115 "A role of a material entity that binds to TLR2 and activates the receptor for pathogen recognition and activation of innate immunity." ; obo:IAO_0000116 "TLR2 agonist role" ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000118 "Toll-like receptor 2 agonist role" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/TLR2" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "TLR2 receptor role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005308 oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "immune response profile" ; rdfs:subClassOf obo:BFO_0000144 . obo:VO_0005309 obo:IAO_0000115 "A biased immune profile that is characterized by the presense of T help cells Type 1 T helper (Th1) cells that produce interferon-gamma, interleukin (IL)-2, and tumour necrosis factor (TNF)-beta, which activate macrophages and are responsible for cell-mediated immunity and phagocyte-dependent protective responses." ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/T_helper_cell", "https://pubmed.ncbi.nlm.nih.gov/10579123/" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "Th1-biased immune profile" ; rdfs:subClassOf obo:VO_0005308 . obo:VO_0005310 obo:IAO_0000115 "A baised immune profile that is characterized by the presense of T type 2 Th (Th2) cells that produce IL-4, IL-5, IL-10, and IL-13, which are responsible for strong antibody production, eosinophil activation, and inhibition of several macrophage functions, thus providing phagocyte-independent protective responses." ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/T_helper_cell", "https://pubmed.ncbi.nlm.nih.gov/10579123/" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "Th2-biased immune profile" ; rdfs:subClassOf obo:VO_0005308 . obo:VO_0005311 obo:IAO_0000115 "An immune profile that is characterized by the presense of both Type 1 and Type 2 T helper (Th1 and Th2) cells." ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/T_helper_cell", "https://pubmed.ncbi.nlm.nih.gov/10579123/" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "Th1/Th2 mixed immune profile" ; rdfs:subClassOf obo:VO_0005308 . obo:VO_0005312 obo:IAO_0000115 "An object property that represents a relation between a material entity (such as vaccine or vaccine adjuvant) and an immune profile where the material entity can induce the immune profile in a host." ; obo:IAO_0000117 "Amogh Madireddi", "Oliver He" ; a owl:ObjectProperty ; rdfs:label "induces immune profile" . obo:VO_0005313 obo:IAO_0000115 "An immune profile that is characterized by the presense of T helper 17 cells (Th17) that a subset of pro-inflammatory T helper cells defined by their production of interleukin 17 (IL-17). They are related to T regulatory cells and the signals that cause Th17s to differentiate actually inhibit Treg differentiation." ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/T_helper_17_cell" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "Th17 immune profile" ; rdfs:subClassOf obo:VO_0005308 . obo:VO_0005314 obo:IAO_0000115 "An immune profile that is characterized by the presense of both Type 1 and Type 17 T helper (Th1 and Th17) cells." ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/T_helper_cell" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "Th1/Th17 mixed immune profile" ; rdfs:subClassOf obo:VO_0005308 . obo:VO_0005315 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by Clover Biopharmaceuticals AUS Pty Ltd that contains the S protein from the B.1.351 variant." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04950751" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SCB-2020S" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005316 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by Bagheiat-allah University of Medical Sciences" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "https://en.irct.ir/trial/56987" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Noora" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005317 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by Baiya Phytopharm Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04953078" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Baiya SARS-CoV-2 Vax 1" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005318 obo:IAO_0000115 "A SARS-CoV-2 recombinant vector vaccine manufactured by CyanVac LLC" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04954287" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CVXGA1" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005319 obo:IAO_0000115 "A SARS-CoV-2 recombinant vector vaccine by AstraZeneca and Oxford University against variant strain B.1.351" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04973449" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AZD2816" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005320 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine manufactured by Shanghai Zerun Biotechnology, Walvax Biotechnology, and CEPI" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04990544" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "202-CoV" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005321 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine by Laboratorios HIPRA" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05007509" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 subunit vaccine by HIPRA" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005322 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine developed by AnGes, named as AG0302-COVID19." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04993586" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AG0302-COVID19" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005323 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "authorized COVID-19 DNA vaccine" ; rdfs:subClassOf obo:VO_0005203, obo:VO_0005264 . obo:VO_0005324 obo:IAO_0000115 "An Advax-CpG vaccine adjuvant that includes an inulin-based polysaccharide (Advax) and a CpG oligodeoxynucleotide CpG55.2." ; obo:IAO_0000116 """Pubmed References:Chemical Nature: (1) combination adjuvant Mechanism of Action: (1) complement, (2) dendritic cells, (3) other/unknown, (4) TLR9 Immune profile induced: mixed Th1 Other Features/Characteristics: (1) induces CD8 T cells, (2) provides innate protection, (3) anti-inflammatory, (4) promotes antibody affinity maturation, (5) effective in newborns, (6) high stability By routes: SQ, IM Point of Contact: Nikolai Petrovsky, Vaxine LTD""" ; obo:IAO_0000117 "Nikolai Petrovsky", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "Advax-CpG55.2" ; obo:IAO_0000119 "https://pubmed.ncbi.nlm.nih.gov/32636840/", "https://vac.niaid.nih.gov/view?id=38", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32849580", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33301675", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34069575" ; obo:VO_0005328 "38" ; a owl:Class ; rdfs:label "Advax-CpG55.2 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0005357, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005325 obo:IAO_0000115 "A vaccine adjuvant that is synthesized by derivatizing a natural Momordica saponin in one step. VSA-2 is chemically stable. VSA-2 is much less toxic than QS-21. VSA-2 is more Th1-biased than QS-21. Momordica saponins are isolated from widely available and sustainable sources." ; obo:IAO_0000116 """Pubmed References: Chemical Nature: (1) Synthetic derivative of natural compound Mechanism of Action: unknown Immune profile induced: mixed Th1/Th2 Other Features/Characteristics: (1) synthetic saponin with lower toxicity and higher stability than QS21 By routes: SQ Point of Contact: Pengfei Wang, University of Alabama https://www.ncbi.nlm.nih.gov/pubmed/?term=32101001""" ; obo:IAO_0000117 "Oliver He", "Pengfei Wang", "Wolfgang Leitner" ; obo:IAO_0000118 "VSA-2" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=42", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32101001" ; obo:VO_0005328 "42" ; a owl:Class ; rdfs:label "VSA-2 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005326 obo:IAO_0000115 "A vaccine adjuvant that is prepared by derivatizing a natural Momordica saponin in one chemical step. VSA-1 is chemically more stable than QS-21. VSA-1 is much less toxic than QS-21. The Momordica saponins are from sustainable sources and widely available." ; obo:IAO_0000116 """Pubmed References: Chemical Nature: (1) Synthetic derivative of natural compound Mechanism of Action: unknown Immune profile induced: mixed Th1/Th2 Other Features/Characteristics: (1) synthetic saponin with lower toxicity and higher stability than QS21 By routes: SQ Point of Contact: Pengfei Wang, University of Alabama https://www.ncbi.nlm.nih.gov/pubmed/?term=31657920""" ; obo:IAO_0000117 "Oliver He", "Pengfei Wang", "Wolfgang Leitner" ; obo:IAO_0000118 "VSA-1" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=41", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31657920" ; obo:VO_0005328 "41" ; a owl:Class ; rdfs:label "VSA-1 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005327 obo:IAO_0000115 "A vaccine adjuvant that is a potent adjuvant for antibody and cellular responses to protein, polypeptide and small peptide antigens. rOv-ASP-1 stands for Recombinant Onchocerca volvulus activation-associated secreted protein-1." ; obo:IAO_0000116 """Pubmed References: Chemical Nature: (1) Protein Mechanism of Action: unknown Immune profile induced: Th1 Other Features/Characteristics: (1) Induces CD8 T cells, (2) provides innate protection, (3) promotes antibody affinity maturation. By routes: IM Point of Contact: Sara Lustigman, New York Blood Center""" ; obo:IAO_0000117 "Oliver He", "Sara Lustigman", "Wolfgang Leitner" ; obo:IAO_0000118 "Recombinant O. volvulus activation-associated secreted protein-1", "rOv-ASP-1" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=43", "https://www.ncbi.nlm.nih.gov/pubmed/?term=1583768", "https://www.ncbi.nlm.nih.gov/pubmed/?term=18341617", "https://www.ncbi.nlm.nih.gov/pubmed/?term=18675867", "https://www.ncbi.nlm.nih.gov/pubmed/?term=22615877", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24681229", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25736195", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26795365", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29764680", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32471056" ; obo:VO_0005328 "43" ; a owl:Class ; rdfs:label "rOv-ASP-1 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005328 obo:IAO_0000115 "An identifier assigned by the Vaccine Adjuvant Compendium (VAC: https://vac.niaid.nih.gov/)" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/" ; a owl:AnnotationProperty ; rdfs:label "VAC adjuvant ID" . obo:VO_0005329 obo:IAO_0000115 "A vaccine adjuvant that includes double mutant of heat-labile E. coli toxin (LT) at R192G/L211A or LT(R192G/L211A)" ; obo:IAO_0000116 """Chemical Nature: protein Mechanism of Action: CGM1 ganglioside, cAMP, inflammasome Immune profile induced: mixed Th1/Th17 Other Features/Characteristics: Induces mucosal immunity (IM, ID, SQ, SL, oral, , transcutaneous), Induces epitope spreading, Promotes antibody affinity maturation, Effective in newborns, promotes antibody epitope spreading By routes: IM, ID, SL, oral, SQ, IN, IP, intragastric, transcutaneous, transdermal, buccal, intrarectal Point of Contact: Elizabeth Norton, Tulane University https://www.ncbi.nlm.nih.gov/pubmed/?term=21288994 https://www.ncbi.nlm.nih.gov/pubmed/?term=6803349 https://www.ncbi.nlm.nih.gov/pubmed/?term=26540197 https://www.ncbi.nlm.nih.gov/pubmed/?term=4927082 https://www.ncbi.nlm.nih.gov/pubmed/?term=26305793 https://www.ncbi.nlm.nih.gov/pubmed/?term=25111827 https://www.ncbi.nlm.nih.gov/pubmed/?term=24453241 https://www.ncbi.nlm.nih.gov/pubmed/?term=22202122 https://www.ncbi.nlm.nih.gov/pubmed/?term=25803825 https://www.ncbi.nlm.nih.gov/pubmed/?term=23541621 https://www.ncbi.nlm.nih.gov/pubmed/?term=26018536 https://www.ncbi.nlm.nih.gov/pubmed/?term=5461379 https://www.ncbi.nlm.nih.gov/pubmed/?term=3578125 https://www.ncbi.nlm.nih.gov/pubmed/?term=5216441 https://www.ncbi.nlm.nih.gov/pubmed/?term=19897067 https://www.ncbi.nlm.nih.gov/pubmed/?term=25944298 https://www.ncbi.nlm.nih.gov/pubmed/?term=6424635 https://www.ncbi.nlm.nih.gov/pubmed/?term=3916310 https://www.ncbi.nlm.nih.gov/pubmed/?term=4826740 https://www.ncbi.nlm.nih.gov/pubmed/?term=2884428 https://www.ncbi.nlm.nih.gov/pubmed/?term=30778066 https://www.ncbi.nlm.nih.gov/pubmed/?term=4893257 https://www.ncbi.nlm.nih.gov/pubmed/?term=28063704 https://www.ncbi.nlm.nih.gov/pubmed/?term=4375349 https://www.ncbi.nlm.nih.gov/pubmed/?term=28792004 https://www.ncbi.nlm.nih.gov/pubmed/?term=25765967 https://www.ncbi.nlm.nih.gov/pubmed/?term=25483682 https://www.ncbi.nlm.nih.gov/pubmed/?term=30638799 https://www.ncbi.nlm.nih.gov/pubmed/?term=21326197 https://www.ncbi.nlm.nih.gov/pubmed/?term=31757774 https://www.ncbi.nlm.nih.gov/pubmed/?term=31427449 https://www.ncbi.nlm.nih.gov/pubmed/?term=6957164 https://www.ncbi.nlm.nih.gov/pubmed/?term=33465933 https://www.ncbi.nlm.nih.gov/pubmed/?term=33465933 https://www.ncbi.nlm.nih.gov/pubmed/?term=33465933 https://www.ncbi.nlm.nih.gov/pubmed/?term=31641151 https://www.ncbi.nlm.nih.gov/pubmed/?term=27133878 https://www.ncbi.nlm.nih.gov/pubmed/?term=27676456 https://www.ncbi.nlm.nih.gov/pubmed/?term=27226279 https://www.ncbi.nlm.nih.gov/pubmed/?term=22406456 https://www.ncbi.nlm.nih.gov/pubmed/?term=30787109 https://www.ncbi.nlm.nih.gov/pubmed/?term=24403527 https://www.ncbi.nlm.nih.gov/pubmed/?term=24403527 https://www.ncbi.nlm.nih.gov/pubmed/?term=30563789 https://www.ncbi.nlm.nih.gov/pubmed/?term=31757774 https://www.ncbi.nlm.nih.gov/pubmed/?term=30473185 https://www.ncbi.nlm.nih.gov/pubmed/?term=30248001 https://www.ncbi.nlm.nih.gov/pubmed/?term=24049109 https://www.ncbi.nlm.nih.gov/pubmed/?term=30797634 https://www.ncbi.nlm.nih.gov/pubmed/?term=31482013 https://www.ncbi.nlm.nih.gov/pubmed/?term=29771685 https://www.ncbi.nlm.nih.gov/pubmed/?term=31757774 https://www.ncbi.nlm.nih.gov/pubmed/?term=25444830 Clinical trials: https://clinicaltrials.gov/ct2/show/NCT03922061 https://clinicaltrials.gov/ct2/show/NCT04232943 https://clinicaltrials.gov/ct2/show/NCT02531685 https://clinicaltrials.gov/ct2/show/NCT02052934 https://clinicaltrials.gov/ct2/show/NCT02531802 https://clinicaltrials.gov/ct2/show/NCT01147445 https://clinicaltrials.gov/ct2/show/NCT03548064 https://clinicaltrials.gov/ct2/show/ NCT01739231 https://clinicaltrials.gov/ct2/show/NCT03404674 https://clinicaltrials.gov/ct2/show/NCT03729219 https://clinicaltrials.gov/ct2/show/NCT04826094""" ; obo:IAO_0000117 "Elizabeth Norton", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "dmLT" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=13", "https://www.ncbi.nlm.nih.gov/pubmed/?term=19897067", "https://www.ncbi.nlm.nih.gov/pubmed/?term=21288994", "https://www.ncbi.nlm.nih.gov/pubmed/?term=22202122", "https://www.ncbi.nlm.nih.gov/pubmed/?term=23541621", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24453241", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25111827", "https://www.ncbi.nlm.nih.gov/pubmed/?term=25803825", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26018536", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26305793", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26540197", "https://www.ncbi.nlm.nih.gov/pubmed/?term=3578125", "https://www.ncbi.nlm.nih.gov/pubmed/?term=4927082", "https://www.ncbi.nlm.nih.gov/pubmed/?term=5216441", "https://www.ncbi.nlm.nih.gov/pubmed/?term=5461379", "https://www.ncbi.nlm.nih.gov/pubmed/?term=6803349" ; obo:VO_0005328 "13" ; a owl:Class ; rdfs:label "dmLT vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005314 ] . obo:VO_0005330 obo:IAO_0000116 """Chemical Nature: (1) other (Peptide) Mechanism of Action: C5aR1 on mononuclear phagocytes Immune profile induced: mixed Th1/Th2 Other Features/Characteristics: (1) Induces CD8 T cells, (2) provides innate protection, (3) promotes antibody affinity maturation. By routes: SQ, IP, IV. Point of Contact: Joseph Vetro, University of Nebraska Medical Center https://pubmed.ncbi.nlm.nih.gov/9013982/, https://pubmed.ncbi.nlm.nih.gov/9013982/, https://pubmed.ncbi.nlm.nih.gov/10516626/, https://pubmed.ncbi.nlm.nih.gov/10799917/, https://pubmed.ncbi.nlm.nih.gov/10799917/, https://pubmed.ncbi.nlm.nih.gov/12538044/, https://pubmed.ncbi.nlm.nih.gov/19428909/, https://pubmed.ncbi.nlm.nih.gov/21723901/""" ; obo:IAO_0000117 "Joseph Vetro", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "CPDI-01" ; obo:IAO_0000119 "https://pubmed.ncbi.nlm.nih.gov/10516626/", "https://pubmed.ncbi.nlm.nih.gov/10799917/", "https://pubmed.ncbi.nlm.nih.gov/12538044/", "https://pubmed.ncbi.nlm.nih.gov/19428909/", "https://pubmed.ncbi.nlm.nih.gov/21723901/", "https://pubmed.ncbi.nlm.nih.gov/9013982/", "https://vac.niaid.nih.gov/view?id=39" ; obo:VO_0005328 "39" ; a owl:Class ; rdfs:label "CPDI-01 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005331 obo:IAO_0000115 "A recombiant vector vaccine that is has a viral vector." ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "recombinant viral vector vaccine" ; rdfs:subClassOf obo:VO_0000484 . obo:VO_0005332 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by Arcturus Therapeutics, Inc., named as ARCT-165." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05037097" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ARCT-165" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005179 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005333 obo:IAO_0000115 "A SARS-CoV-2 monovalent protein subunit vaccine by Novavax immunizing against the B.1.351 (Beta) variant and containing the Matrix-M1 adjuvant" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05029856" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SII B.1.351" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005334 obo:IAO_0000115 "A SARS-CoV-2 bivalent protein subunit vaccine by Novavax containing antigen for both the ancestral strain and B.1.351 (Beta) variant." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05029856" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SII Bivalent" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005335 obo:IAO_0000115 "A SARS-CoV-2 monovalent protein subunit vaccine by Novavax immunizing against the B.1.617.2 (Delta) variant and containing the Matrix-M1 adjuvant" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05029856" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SII B.1.617.2" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005336 obo:IAO_0000115 "A SARS-CoV-2 recombinant viral vector vaccine by Biocad" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05037188" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AAV5-RBD-S" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005337 obo:IAO_0000115 "A vaccine adjuvant that includes UM-3005, a small molecule TLR7/8 agonist that can stimulate Th1-biased immune profile." ; obo:IAO_0000116 """Chemical Nature: (1) small molecule Mechanism of Action: TLR7/8 agonist Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Helene Bazin-Lee, InImmune""" ; obo:IAO_0000117 "Ani M. Bernardi", "Helene Bazin-Lee", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "UM-3005" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=47", "https://www.ncbi.nlm.nih.gov/pubmed/32210973" ; obo:VO_0005328 "47" ; a owl:Class ; rdfs:label "UM-3005 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005272 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005306 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005338 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by Sinocelltech Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05043311" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SCTV01C" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005339 obo:IAO_0000115 "A SARS-CoV-2 replication deficient human adenovirus vector vaccine expressing the spike, nucleocapsid and RNA polymerase proteins." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05094609" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ad5-triCoV/Mac" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005340 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine developed by Vaccibody AS encoding the receptor-binding domain" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05069623" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VB10.2129" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005341 obo:IAO_0000115 "A SARS-CoV-2 T-Cell-based DNA vaccine developed by Vaccibody AS" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05069623" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VB10.2210" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005342 obo:IAO_0000115 "A SARS-CoV-2 replication deficient chimpanzee adenovirus 68 vector vaccine expressing the spike, nucleocapsid and RNA polymerase proteins." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05094609" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ChAd-triCoV/Mac" ; rdfs:subClassOf obo:VO_0005200, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000341 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005343 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by PT Bio Farma" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05067894" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 subunit vaccine by PT Bio Farma" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005344 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine developed by Scancell Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05047445" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVIDITY" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005345 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by Yisheng Biopharma" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "ACTRN12621001009808" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PIKA Recombinant COVID-19 Vaccine" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005346 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine developed by University of Hong Kong and Immuno Cure 3 Limited" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05102643" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 DNA vaccine by the University of Hong Kong and Immuno Cure 3 Limited" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005347 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by Arcturus Therapeutics, Inc., named as ARCT-154." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "ISRCTN15779782" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ARCT-154" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:PR_P0DTC2 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000530 ; owl:someValuesFrom obo:VO_0005179 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005348 obo:IAO_0000115 "A COVID-19 virus-like particle vaccine developed by Yantai Patronus Biotech Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05137444" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LYB001" ; rdfs:subClassOf obo:VO_0005205, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005349 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine developed by the National Research Centre of Egypt" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05128721" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Covi Vax" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005350 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine containing a T-cell priming specific cocktail of Coronaviruses peptides mounted on a gold nanoparticle." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05113862" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "naNO-COVID" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005351 obo:IAO_0000115 "A SARS-CoV-2 subunit vaccine by HK inno.N Corporation" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05113849" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IN-B009" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005352 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine manufactured by VLP Therapeutics Japan, LLC" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "jRCT2071210067" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VLPCOV-01" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005353 obo:IAO_0000115 "A vaccine adjuvant that includes UM-3004, a small molecule TLR7/8 agonist that can stimulate Th1-biased immune profile." ; obo:IAO_0000116 """Chemical Nature: (1) small molecule Mechanism of Action: TLR7/8 agonist Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Helene Bazin-Lee, University of Montana""" ; obo:IAO_0000117 "Ani M. Bernardi", "Helene Bazin-Lee", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "UM-3004" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=46", "https://www.ncbi.nlm.nih.gov/pubmed/32210973" ; obo:VO_0005328 "46" ; a owl:Class ; rdfs:label "UM-3004 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005272 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005306 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005354 obo:IAO_0000115 "A vaccine adjuvant that includes UM-3003, a small molecule TLR7/8 agonist that can stimulate Th1-biased immune profile." ; obo:IAO_0000116 """Chemical Nature: (1) small molecule Mechanism of Action: TLR7/8 agonist Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Helene Bazin-Lee, University of Montana""" ; obo:IAO_0000117 "Ani M. Bernardi", "Helene Bazin-Lee", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "UM-3003" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=45", "https://www.ncbi.nlm.nih.gov/pubmed/32210973" ; obo:VO_0005328 "45" ; a owl:Class ; rdfs:label "UM-3003 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005272 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005306 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005355 obo:IAO_0000115 "A vaccine adjuvant made from the A subunit of heat-labile (LT) enterotoxin of Enterotoxigenic Escherichia coli (ETEC). This LTA1 adjuvant is able to induce Th1, Th2, and Th17 immune responses." ; obo:IAO_0000116 """Chemical Nature: (1) Protein Mechanism of Action: cAMP, inflammasome induction Immune profile induced: mixed Th1/Th2/Th17 Other Features/Characteristics: (1) Induces mucosal immunity, (2) Induces epitope spreading, (3) Promotes antibody affinity maturation, (4) Promotes antibody epitope spreading, (5) High stability Route of immunization: IM, IN, SL, ID, IP Point of Contact: Elizabeth Norton, Tulane University""" ; obo:IAO_0000117 "Ani M. Bernardi", "Elizabeth Norton", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "LTA1" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=44", "https://www.ncbi.nlm.nih.gov/pubmed/22526674", "https://www.ncbi.nlm.nih.gov/pubmed/26305793", "https://www.ncbi.nlm.nih.gov/pubmed/31427449", "https://www.ncbi.nlm.nih.gov/pubmed/31641151", "https://www.ncbi.nlm.nih.gov/pubmed/31929548", "https://www.ncbi.nlm.nih.gov/pubmed/33986280", "https://www.ncbi.nlm.nih.gov/pubmed/34516780", "https://www.ncbi.nlm.nih.gov/pubmed/6957164" ; obo:VO_0005328 "44" ; a owl:Class ; rdfs:label "LTA1 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005310 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005313 ] . obo:VO_0005356 obo:IAO_0000115 "A carbohydrate vaccine adjuvant that is a glucan carbohydrate microcapsules with a Œ≤(1-3)/Œ≤(1-6)-linked glucan structure to allow targeting of antigens to macrophages or neutrophils through interactions with the Œ≤-glucan receptor found uniquely on the surface of these cell types. Adjuvax-ligand complexes are formed by physically entrapping or crosslinking the ligand within the Œ≤-glucan." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000119 "DOI: 10.1021" ; a owl:Class ; rdfs:label "Adjuvax vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001359 . obo:VO_0005357 obo:IAO_0000115 "A vaccine adjuvant that includes an inulin-based polysaccharide (Advax) and a CpG oligodeoxynucleotide (ODN)." ; obo:IAO_0000116 """Pubmed References:Chemical Nature: (1) combination adjuvant Mechanism of Action: (1) complement, (2) dendritic cells, (3) other/unknown, (4) TLR9 Immune profile induced: mixed Th1 Other Features/Characteristics: (1) induces CD8 T cells, (2) provides innate protection, (3) anti-inflammatory, (4) promotes antibody affinity maturation, (5) effective in newborns, (6) high stability By routes: SQ, IM Point of Contact: Nikolai Petrovsky, Vaxine LTD""" ; obo:IAO_0000117 "Nikolai Petrovsky", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "Advax-2", "Advax-CpG", "Advax-SM" ; obo:IAO_0000119 "https://pubmed.ncbi.nlm.nih.gov/32636840/", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32849580", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33301675", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34069575" ; a owl:Class ; rdfs:label "Advax-CpG vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005358 obo:IAO_0000115 "A combination vaccine adjuvant includes 3-O-desacyl-4‚Äô-monophosphoryl lipid A (MPL) from Salmonella minnesota and a saponin molecule (QS-21) purified from plant extract Quillaja saponaria Molina, combined in a liposomal formulation consisting of dioleoyl phosphatidylcholine (DOPC) and cholesterol in phosphate-buffered saline solution." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000119 "https://www.fda.gov/media/107538/download#:~:text=The%20AS01B%20adjuvant%20suspension%20is,DOPC)%20and%20cholesterol%20in%20phosphate%2D" ; a owl:Class ; rdfs:label "AS01B vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354 . obo:VO_0005359 obo:IAO_0000115 "An AS02 vaccine adjuvant contains 50 ug MPL and 50ug QS21, 250uL of SB62 (oil/water emulsion) in phosphate buffered saline (PBS) per volume of 0.5 mL." ; obo:IAO_0000118 "As02a" ; obo:IAO_0000119 "https://clinicaltrials.gov/ct2/show/NCT00308061" ; a owl:Class ; rdfs:label "AS02A vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001264 . obo:VO_0005360 obo:IAO_0000115 "A carbohydrate vaccine adjuvant that is aminoglycan consisting of Œ≤-(1->4)-linked¬†D-glucosamine residues." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000119 "CHEBI:16261", "PMID:24346613" ; a owl:Class ; rdfs:label "chitosan vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001359 . obo:VO_0005361 obo:IAO_0000115 "A Montanide vaccine adjuvant that is a water-dispersed liquid IMS 1313 nanoparticle combined with an immuno-stimulating compound." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000118 "IMS 1313 N VGPR", "IMS-1313" ; obo:IAO_0000119 "https://scialert.net/abstract/?doi=ijps.2018.167.174" ; a owl:Class ; rdfs:label "Montanide IMS 1313 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001271 . obo:VO_0005362 obo:IAO_0000115 "A water-dispersed liquid nanoparticle combined with an immuno-stimulating compound." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000118 "ISA-206" ; obo:IAO_0000119 "PMID:8961504" ; a owl:Class ; rdfs:label "Montanide ISA 206 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001271 . obo:VO_0005363 obo:IAO_0000115 "A Montanide vaccine adjuvant that Mannide oleate derivative in a mineral oil solution ( Seppic SA, France)." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000118 "ISA-50" ; obo:IAO_0000119 "http://vetarhiv.vef.unizg.hr/papers/74-2/raman.pdf" ; a owl:Class ; rdfs:label "Montanide ISA 50 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001271 . obo:VO_0005364 obo:IAO_0000115 "A carbohydrate vaccine adjuvant that is tomatidine in which the hydroxy group at position 3 is linked to lycotetraose, a tetrasaccharide composed of two units of D-glucose, one unit of D-xylose, and one unit of D-galactose." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000119 "CHEBI:9630" ; a owl:Class ; rdfs:label "Tomatine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001359 . obo:VO_0005365 obo:IAO_0000115 "A carbohydrate vaccine adjuvant that polysaccharide prepared from the cell wall of Saccaromyces cerevisiae (bakers' yeast)." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000119 "PMID:11380697" ; a owl:Class ; rdfs:label "Zymosan vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001359 . obo:VO_0005366 obo:IAO_0000115 "An emulsion vaccine adjuvant that is oil-based adjuvant (Adjuvant XtendIII®; Grand Laboratories, Larchwood, IA)." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; a owl:Class ; rdfs:label "XtendIII vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355 . obo:VO_0005367 obo:IAO_0000115 "A microbial derivative vaccine adjuvant that is monophosphoryl lipid A (detoxified endotoxin) from S. minnesota (MPL) and synthetic trehalose dicorynomycolate (TDM) in 2% oil (squalene)-Tween 80-water." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000118 "Monophosphoryl-lipid A + Trehalose dicorynomycolate" ; obo:IAO_0000119 "https://www.sigmaaldrich.com/US/en/product/sigma/m6536" ; a owl:Class ; rdfs:label "MPL + TDM vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000118 . obo:VO_0005368 obo:IAO_0000115 "A muramyl dipeptide vaccine adjuvant that muramyl dipeptide derivative (threonyl-MDP) in an oil-in-water (o/w) emulsion vehicle." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000118 "SAF" ; obo:IAO_0000119 "https://link.springer.com/protocol/10.1385/1-59259-083-7:229" ; a owl:Class ; rdfs:label "Syntex Adjuvant Formulation" ; rdfs:subClassOf obo:VO_0000187 . obo:VO_0005369 obo:IAO_0000115 "A vaccine adjuvant that diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000118 "DBP" ; obo:IAO_0000119 "CHEBI:34687", "PMID:26319029" ; a owl:Class ; rdfs:label "dibutyl phthalate vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005313 ] . obo:VO_0005370 obo:IAO_0000115 "A vaccine adjuvant that includes naturally occurring trivalent alcohol." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000118 "glycerine, 1, 2, 3-propanetriol" ; obo:IAO_0000119 "https://academic.oup.com/cid/article/45/10/1277/277413" ; a owl:Class ; rdfs:label "glycerol vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005313 ] . obo:VO_0005371 obo:IAO_0000115 "A vaccine adjuvant includes three palmitic acid groups that are bound in an ester and amide linkage to a cysteine residue." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000118 "Tripalmitoyl-S-glyceryl-cysteine" ; obo:IAO_0000119 "PMID:24130558" ; a owl:Class ; rdfs:label "Pam3Cys vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005313 ] . obo:VO_0005372 obo:IAO_0000115 "A vaccine adjuvant that is equimolar mixture of the cationic lipid GAP-DMORIE [(±)-N-(3-aminopropyl)-N,N-dimethyl-2,3-bis(cis-9-tetradecenyloxy)-1-propanaminium bromide)] and a neutral colipid DPyPE (1,2-diphytanoyl-sn-glydero-3-phosphoethanolamine)." ; obo:IAO_0000117 "Oliver He", "Randi Vita" ; obo:IAO_0000119 "PMID:21118032" ; a owl:Class ; rdfs:label "Vaxfectin vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005313 ] . obo:VO_0005373 obo:IAO_0000115 "A vaccination process that involves adding a vaccine into a host prior to disease." ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000118 "preventive vaccination" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Preventive_healthcare", "preventative vaccination" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "prophylactic vaccination" ; rdfs:subClassOf obo:VO_0000002 . obo:VO_0005374 obo:IAO_0000115 "A vaccination process that involves adding a vaccine into a host after a disease has occurred." ; obo:IAO_0000117 "Randi Vita, Oliver He" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Therapeutic_vaccines" ; oboInOwl:inSubset "vaccination" ; a owl:Class ; rdfs:label "therapeutic vaccination" ; rdfs:subClassOf obo:VO_0000002 . obo:VO_0005375 obo:IAO_0000115 "A vaccine adjuant that is derived from Salmonella enterica serovar typhimurium and is able to induce Th1/Th2/Th17 immune responses through the mechanism of action of TLR4, inflammasome, and DC activation." ; obo:IAO_0000116 """Chemical Nature: other Mechanism of Action: TLR4; inflammasome; DC activation Immune profile induced: Th1/Th2/Th17 Receptor: TLR4, NLRP3 Storage information: -20 or -80C Point of Contact: Lisa Morici, Tulane University""" ; obo:IAO_0000117 "Lisa Morici", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "T-vant" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=61", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33498352", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34069796" ; obo:VO_0005328 "61" ; a owl:Class ; rdfs:label "T-vant vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005378 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005376 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005377 ; owl:someValuesFrom obo:PR_000001155 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005377 ; owl:someValuesFrom obo:PR_000011271 ] . obo:VO_0005376 obo:IAO_0000115 "An immune profile that is characterized by the presense of Type 1 Type 2, and Th17 T helper cells." ; obo:IAO_0000117 "Oliver He, Amogh Madireddi" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/T_helper_cell", "https://pubmed.ncbi.nlm.nih.gov/10579123/" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "Th1/Th2/Th17 mixed immune profile" ; rdfs:subClassOf obo:VO_0005308 . obo:VO_0005377 obo:IAO_0000112 "A vaccine adjuvant T-vant has molecular receptor of TLR4. Reference: https://vac.niaid.nih.gov/view?id=61." ; obo:IAO_0000115 "An object property that represents a relation between a material entity and a molecular entitiy that serves as the molecular receptor to the material entity." ; obo:IAO_0000117 "Oliver He" ; a owl:ObjectProperty ; rdfs:label "has molecular receptor" . obo:VO_0005378 obo:IAO_0000115 "A role of a material entity that binds to NLRP3." ; obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/NLRP3" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "NLRP3 receptor role" ; rdfs:subClassOf obo:BFO_0000023 . obo:VO_0005379 obo:IAO_0000116 """Chemical Nature: Nucleic Acid Mechanism of Action: TLR/RLR-agonist Immune profile induced: Th1/Th2 Route of immunization: IM and IN Point of Contact: Xiaoliang Ren, Yisheng Bio Ongoing clinical trial: https://clinicaltrials.gov/ct2/show/NCT02657161 https://clinicaltrials.gov/ct2/show/NCT02956421""" ; obo:IAO_0000117 "Oliver He", "Wolfgang Leitner", "Xiaoliang Ren" ; obo:IAO_0000118 "PIKA" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=55", "https://www.ncbi.nlm.nih.gov/pubmed/?term=17484805", "https://www.ncbi.nlm.nih.gov/pubmed/?term=20538850", "https://www.ncbi.nlm.nih.gov/pubmed/?term=21468931", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26765968", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28118938", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29174316", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34766005" ; obo:VO_0005328 "55" ; a owl:Class ; rdfs:label "PIKA vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005380 obo:IAO_0000116 """Chemical Nature: peptide Mechanism of Action: activation of mast cells, epithelial cells, macrophages and dendritic cells Immune profile induced: Th2-biased Route of immunization: IM and IN Point of Contact: Herman Staats, Duke University""" ; obo:IAO_0000117 "Herman Staats", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "Mastoparan 7" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=53", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31068425", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32047657", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34566991" ; obo:VO_0005328 "53" ; a owl:Class ; rdfs:label "Mastoparan 7 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005310 ] . obo:VO_0005381 obo:IAO_0000116 """Chemical Nature: small molecule Mechanism of Action: mast cell activation Immune profile induced: Th2-biased Route of immunization: IN Point of Contact: Herman Staats, Duke University""" ; obo:IAO_0000117 "Herman Staats", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "Mast cell activator small molecules" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=54", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34566991" ; obo:VO_0005328 "54" ; a owl:Class ; rdfs:label "Mast cell activator small molecules vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005310 ] . obo:VO_0005382 obo:IAO_0000116 """Chemical Nature: small molecule Mechanism of Action: Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Ofer Levy, Precision Vaccines Program at Boston Children's Hospital""" ; obo:IAO_0000117 "Ofer Levy", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "Precision Vaccines Program (PVP)-037" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=56" ; obo:VO_0005328 "56" ; a owl:Class ; rdfs:label "Precision Vaccines Program (PVP)-037 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005383 obo:IAO_0000116 """Chemical Nature: small molecule Mechanism of Action: TLR4 agonist Immune profile induced: Th1/Th2 Route of immunization: IM and IN Point of Contact: Robert Ernst, University of Maryland - Baltimore""" ; obo:IAO_0000117 "Oliver He", "Robert Ernst", "Wolfgang Leitner" ; obo:IAO_0000118 "BECC470s" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=60" ; obo:VO_0005328 "60" ; a owl:Class ; rdfs:label "BECC470s vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005384 obo:IAO_0000116 """Chemical Nature: small molecule Mechanism of Action: innate immune activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Helene Bazin-Lee, University of Montana""" ; obo:IAO_0000117 "Helene Bazin-Lee", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "TRAC478" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=48" ; obo:VO_0005328 "48" ; a owl:Class ; rdfs:label "TRAC478 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005385 obo:IAO_0000116 """Chemical Nature: small molecule Mechanism of Action: innate immune activation Immune profile induced: Th1/Th17 Route of immunization: IM and IN Point of Contact: Christopher Fox, AAHI""" ; obo:IAO_0000117 "Christopher Fox", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "GLA-3M-052-LS" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=58", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34248966", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34795290" ; obo:VO_0005328 "58" ; a owl:Class ; rdfs:label "GLA-3M-052-LS vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005314 ] . obo:VO_0005386 obo:IAO_0000116 """Chemical Nature: small molecule Mechanism of Action: innate immune activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Christopher Fox, AAHI""" ; obo:IAO_0000117 "Christopher Fox", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "3M-052-SE" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=57", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28429728", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30089691", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32213623", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34131024", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34972105", "https://www.ncbi.nlm.nih.gov/pubmed/?term=35572573" ; obo:VO_0005328 "57" ; a owl:Class ; rdfs:label "3M-052-SE vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005387 obo:IAO_0000116 """Chemical Nature: small molecule Mechanism of Action: innate immune activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Christopher Fox, AAHI Clinical trials: https://clinicaltrials.gov/ct2/show/NCT04177355 https://clinicaltrials.gov/ct2/show/NCT04915768 https://clinicaltrials.gov/ct2/show/NCT05197712""" ; obo:IAO_0000117 "Christopher Fox", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "3M-052-Alum" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=59", "https://www.ncbi.nlm.nih.gov/pubmed/?term=27847326", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32561559", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33971664", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34117252", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34266981" ; obo:VO_0005328 "59" ; a owl:Class ; rdfs:label "3M-052-Alum vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005388 obo:IAO_0000116 """Chemical Nature: (1) emulsion Mechanism of Action: unknown Immune profile induced: Th1/Th17 Route of immunization: IM Point of Contact: Patrice Dubois, Vaccine Formulation Institute Clinical trial: https://clinicaltrials.gov/ct2/show/NCT04702178""" ; obo:IAO_0000117 "Oliver He", "Patrice Dubois", "Wolfgang Leitner" ; obo:IAO_0000118 "SWE" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=50", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30849373", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32411401" ; obo:VO_0005328 "50" ; a owl:Class ; rdfs:label "SWE vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005314 ] . obo:VO_0005389 obo:IAO_0000116 """Chemical Nature: (1) Emulsion (with Saponin) Mechanism of Action: unknown Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Patrice Dubois, Vaccine Formulation Institute""" ; obo:IAO_0000117 "Oliver He", "Patrice Dubois", "Wolfgang Leitner" ; obo:IAO_0000118 "SQ" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=52", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33688647" ; obo:VO_0005328 "52" ; a owl:Class ; rdfs:label "SQ vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005390 obo:IAO_0000116 """Chemical Nature: (1) other (liposome with Saponin) Mechanism of Action: unknown Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Patrice Dubois, Vaccine Formulation Institute""" ; obo:IAO_0000117 "Oliver He", "Patrice Dubois", "Wolfgang Leitner" ; obo:IAO_0000118 "LQ" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=51", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32156809", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33688647" ; obo:VO_0005328 "51" ; a owl:Class ; rdfs:label "LQ vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005391 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by Suzhou Abogen Biosciences Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05434585" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ABO1009-DP" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005392 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by ACM Biolabs." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05385991" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ACM-001" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005393 obo:IAO_0000115 "A SARS-CoV-2 DNA vaccine developed by Imam Abdulrahman Bin Faisal University." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05171946" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Almansour-001" ; rdfs:subClassOf obo:VO_0005203, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005394 obo:IAO_0000115 "A synthetic modified vaccinia Ankara (MVA)-based SARS-CoV-2 vaccine" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT04639466" ; oboInOwl:hasAlternativeId "VO:0005176" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Synthetic MVA-based SARS-CoV-2 Vaccine COH04S1" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005395 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by the University of Melbourne." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05272605" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DoCo-Pro-RBD-1 + MF59" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005396 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine developed by Eva Pharma." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05218070" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EgyVax" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005397 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by Gritstone Bio, Inc." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05435027" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GRT-R912" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005398 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by the University of Melbourne." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05272605" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "MIPSCo-mRNA-RBD-1" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005399 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine developed by Osve Pharmaceutical Company." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "IRCT20210622051670N1" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Osvid-19" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005400 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by Speransa Therapeutics." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05389319" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Prime-2-CoV-Beta" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005401 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by Wuhan Recogen Biotechnology Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05366296" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RH109" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005402 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by Walvax Biotechnology and Shanghai RNACure Biopharma" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05394012" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RQ3013" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005403 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by RVAC Medicines" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05420077" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RVM-V001" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005404 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by Vaxxas Pty Ltd" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "ACTRN12622000597796" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "VXS-1223" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005405 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by ImmunityBio, Inc." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05370040" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "AAHI-SC2" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005406 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by Human Stem Cell Institute" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05270954" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Betuvax-CoV2" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005407 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by CanSino Biologics Inc." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05373472" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "COVID-19 mRNA vaccine by CanSino Biologics" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005408 obo:IAO_0000115 "A SARS-CoV-2 RNA vaccine by EyeGene Inc." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05188469" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "EG-COVID" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005409 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine by Moderna that combines the mRNA-1273 COVID-19 vaccine and the mRNA-1010 influenza vaccine." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05375838" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "mRNA-1073" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005410 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine by CSPC ZhongQi Pharmaceutical Technology Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05439824" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SYS6006" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005411 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine developed by Airlangga University" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05226429" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "UNAIR Inactivated COVID-19 Vaccine" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005412 obo:IAO_0000115 "A SARS-CoV-2 protein subunit vaccine manufactured by Livzon Pharmaceutical Group Inc." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05273528" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V-01-351/V-01D Bivalence Vaccine" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005413 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine by Gennova Biopharmaceuticals Limited" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "CTRI/2022/04/041880" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "GEMCOVAC-19" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005414 obo:IAO_0000115 "A SARS-CoV-2 mRNA vaccine by AIM Vaccine Co., Ltd." ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05428592" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "LVRNA009" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005415 obo:IAO_0000115 "A SARS-CoV-2 bivalent mRNA vaccine by Moderna that contains the mRNA-1273 COVID-19 vaccine and the mRNA-1273.214 Omicron booster" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05436834" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "mRNA-1273.214" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005416 obo:IAO_0000115 "A SARS-CoV-2 mRNA booster vaccine by Moderna that targets the Omicron variant" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05249829" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "mRNA-1273.529" ; rdfs:subClassOf obo:VO_0005198, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005417 obo:IAO_0000115 "A SARS-CoV-2 inactivated vaccine developed by China National Biotec Group Company Limited" ; obo:IAO_0000117 "Philip Huang" ; obo:IAO_0000119 "NCT05374954" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Omicron COVID-19 inactivated vaccine by China National Biotec Group Company Limited" ; rdfs:subClassOf obo:VO_0005201, [ a owl:Restriction ; owl:onProperty obo:VO_0000520 ; owl:someValuesFrom obo:NCBITaxon_2697049 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0005418 obo:IAO_0000117 "Oliver He" ; obo:IAO_0000119 "http://www.violinet.org/cov19vaxkb/authorizedcov19vax.php" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "authorized COVID-19 virus-like particle vaccine" ; rdfs:subClassOf obo:VO_0005205, obo:VO_0005264 . obo:VO_0005419 obo:IAO_0000116 """Chemical Nature: other Mechanism of Action: Activation of APCs, activation of T cells and stimulating B cell proliferation (IgG) Immune profile induced: Th1-biased Route of immunization: IM and SQ Point of Contact: Matthew Heath, Allergy Therapeutics (UK) Ltd""" ; obo:IAO_0000117 "Ani Bernardi", "Ari Joffe", "Matthew Heath", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "MCT", "MCT vaccine adjuvant", "MicroCrystalline Tyrosine" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=25", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28347293", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28468322", "https://www.ncbi.nlm.nih.gov/pubmed/?term=28953265", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29592962" ; obo:VO_0005328 "25" ; a owl:Class ; rdfs:label "MicroCrystalline Tyrosine vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005420 obo:IAO_0000116 """Chemical Nature: other Mechanism of Action: TLR4; Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Christopher Fox, AAHI Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=27142329 https://www.ncbi.nlm.nih.gov/pubmed/?term=21060869 https://www.ncbi.nlm.nih.gov/pubmed/?term=20944089 https://www.ncbi.nlm.nih.gov/pubmed/?term=20944089 https://www.ncbi.nlm.nih.gov/pubmed/?term=20944089 https://www.ncbi.nlm.nih.gov/pubmed/?term=21816196 https://www.ncbi.nlm.nih.gov/pubmed/?term=21690242 https://www.ncbi.nlm.nih.gov/pubmed/?term=21060869 https://www.ncbi.nlm.nih.gov/pubmed/?term=22291184 https://www.ncbi.nlm.nih.gov/pubmed/?term=22291184 https://www.ncbi.nlm.nih.gov/pubmed/?term=23045649 https://www.ncbi.nlm.nih.gov/pubmed/?term=23045649 https://www.ncbi.nlm.nih.gov/pubmed/?term=22509423 https://www.ncbi.nlm.nih.gov/pubmed/?term=22896687 https://www.ncbi.nlm.nih.gov/pubmed/?term=23904160 https://www.ncbi.nlm.nih.gov/pubmed/?term=23954378 https://www.ncbi.nlm.nih.gov/pubmed/?term=22425788 https://www.ncbi.nlm.nih.gov/pubmed/?term=22891286 https://www.ncbi.nlm.nih.gov/pubmed/?term=22891286 https://www.ncbi.nlm.nih.gov/pubmed/?term=23624057 https://www.ncbi.nlm.nih.gov/pubmed/?term=23624057 https://www.ncbi.nlm.nih.gov/pubmed/?term=23228811 https://www.ncbi.nlm.nih.gov/pubmed/?term=25024362 https://www.ncbi.nlm.nih.gov/pubmed/?term=25030053 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https://www.ncbi.nlm.nih.gov/pubmed/?term=33046728 https://www.ncbi.nlm.nih.gov/pubmed/?term=31690678 https://www.ncbi.nlm.nih.gov/pubmed/?term=31174937 https://www.ncbi.nlm.nih.gov/pubmed/?term=30567978 https://www.ncbi.nlm.nih.gov/pubmed/?term=31362695 https://www.ncbi.nlm.nih.gov/pubmed/?term=29769270 https://www.ncbi.nlm.nih.gov/pubmed/?term=31521953 https://www.ncbi.nlm.nih.gov/pubmed/?term=28298421 Ongoing clinical trial: https://clinicaltrials.gov/ct2/show/NCT01484548 https://clinicaltrials.gov/ct2/show/NCT01751048 https://clinicaltrials.gov/ct2/show/NCT02071758 https://clinicaltrials.gov/ct2/show/NCT02465216 https://clinicaltrials.gov/ct2/show/NCT01927159 https://clinicaltrials.gov/ct2/show/NCT01599897 https://clinicaltrials.gov/ct2/show/NCT01154049 https://clinicaltrials.gov/ct2/show/NCT03302897 https://clinicaltrials.gov/ct2/show/NCT02465216 https://clinicaltrials.gov/ct2/show/NCT02508376 https://clinicaltrials.gov/ct2/show/NCT03806686 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"https://vac.niaid.nih.gov/view?id=62", "https://www.ncbi.nlm.nih.gov/pubmed/?term=20944089", "https://www.ncbi.nlm.nih.gov/pubmed/?term=21060869", "https://www.ncbi.nlm.nih.gov/pubmed/?term=27142329" ; obo:VO_0005328 "62" ; a owl:Class ; rdfs:label "GLA-SE vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0005421 obo:IAO_0000116 """Chemical Nature: other Mechanism of Action: TLR4; Innate Immune Activation Immune profile induced: Mixed Th1/Th2 Route of immunization: IM Point of Contact: Christopher Fox, AAHI Ongoing clinical trial: https://clinicaltrials.gov/ct2/show/NCT02508376 https://clinicaltrials.gov/ct2/show/NCT02647489 https://clinicaltrials.gov/ct2/show/NCT04177355 https://clinicaltrials.gov/ct2/show/NCT03589794""" ; obo:IAO_0000117 "Ani Bernardi", "Ari Joffe", "Christopher Fox", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "GLA-SLQ" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=63", "https://www.ncbi.nlm.nih.gov/pubmed/?term=22896687", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24465426", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24551202", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24556505", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26541135", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26862758", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31174937", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31690678", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32636844" ; obo:VO_0005328 "63" ; a owl:Class ; rdfs:label "GLA-SLQ vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005422 obo:IAO_0000116 """Chemical Nature: other Mechanism of Action: TLR4; Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Christopher Fox, AAHI""" ; obo:IAO_0000117 "Ani Bernardi", "Ari Joffe", "Christopher 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"https://www.ncbi.nlm.nih.gov/pubmed/?term=30386348", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31149350", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31891152", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32540272", "https://www.ncbi.nlm.nih.gov/pubmed/?term=35459225" ; obo:VO_0005328 "65" ; a owl:Class ; rdfs:label "SLA-SE vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ] . obo:VO_0005424 obo:IAO_0000116 """Chemical Nature: other Mechanism of Action: TLR4; Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Christopher Fox, AAHI Ongoing clinical trial: https://clinicaltrials.gov/ct2/show/NCT02508376 https://clinicaltrials.gov/ct2/show/NCT02647489 https://clinicaltrials.gov/ct2/show/NCT04177355 https://clinicaltrials.gov/ct2/show/NCT03589794""" ; obo:IAO_0000117 "Ani Bernardi", "Ari Joffe", "Christopher Fox", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "GLA-AF" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=66", "https://www.ncbi.nlm.nih.gov/pubmed/?term=22896687", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24465426", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24551202", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24556505", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26541135", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26862758", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31174937", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31690678", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32636844" ; obo:VO_0005328 "66" ; a owl:Class ; rdfs:label "GLA-AF vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0005304 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005425 obo:IAO_0000115 "A cancer vaccine that is used against prostate cancer." ; obo:IAO_0000117 "Oliver He", "Penny Pan" ; obo:IAO_0000119 "https://www.hopkinsmedicine.org/health/conditions-and-diseases/prostate-cancer/immunotherapy-for-prostate-cancer" ; a owl:Class ; rdfs:label "prostate cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0005426 obo:IAO_0000115 "A cancer vaccine that is used against colorectal cancer" ; obo:IAO_0000117 "Oliver He", "Penny Pan" ; obo:IAO_0000119 "PubMed:35990683" ; a owl:Class ; rdfs:label "colorectal cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9256 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9256 ] . obo:VO_0005427 obo:IAO_0000115 "A cancer vaccine that is used against lymphoma." ; obo:IAO_0000117 "Oliver He", "Penny Pan" ; obo:IAO_0000119 "http://www.cancer.gov/news-events/cancer-currents-blog/2019/in-situ-vaccine-non-hodgkin-lymphoma" ; a owl:Class ; rdfs:label "lymphoma vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ] . obo:VO_0005428 obo:IAO_0000115 "A cancer vaccine that is used against brain canceer." ; obo:IAO_0000117 "Oliver He", "Penny Pan" ; obo:IAO_0000119 "https://www.criver.com/eureka/brain-cancer-vaccine-gliomas-moves-forward-clinic" ; a owl:Class ; rdfs:label "brain cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ] . obo:VO_0005429 obo:IAO_0000115 "A cancer vaccine that is used against liver canceer." ; obo:IAO_0000117 "Oliver He", "Penny Pan" ; obo:IAO_0000119 "https://www.creative-biolabs.com/vaccine/liver-cancer-vaccines.htm" ; a owl:Class ; rdfs:label "liver cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ] . obo:VO_0005430 obo:IAO_0000115 "A cancer vaccine that is used against pancreatic canceer." ; obo:IAO_0000117 "Oliver He", "Penny Pan" ; obo:IAO_0000119 "https://www.hopkinsmedicine.org/health/conditions-and-diseases/pancreatic-cancer/pancreatic-cancer-vaccine" ; a owl:Class ; rdfs:label "pancreatic cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ] . obo:VO_0005431 obo:IAO_0000115 "An annotation property that represents the annotated information about the antigens used for a specific vaccine." ; obo:IAO_0000117 "Oliver He", "Penny Pan" ; obo:IAO_0000119 "https://en.wikipedia.org/wiki/Antigen" ; a owl:AnnotationProperty ; rdfs:label "vaccine antigen annotation" . obo:VO_0005432 a owl:AnnotationProperty ; rdfs:label "vaccine preparation annotation" . obo:VO_0005433 a owl:AnnotationProperty ; rdfs:label "vaccine response annotation" . obo:VO_0005434 obo:IAO_0000115 "A recombinant viral vaccine vector that uses PVSRIPO, a recombinant nonpathogenic polio-rhinovirus chimera. PVSRIPO is an engineerable oncolytic virus whereas its internal ribosomal entry site element can be substituted to demolish its cytopathogenic effect. PVSRIPO has a natural inherent tropism for antigen-presenting cells (including dendritic cells and macrophages) due to the presence of the CD-155 receptor on their cellular surfaces. This enables it of inducing CD8+ T-cell mediate immune responses." ; obo:IAO_0000117 "Mina Ashraf, Oliver He" ; obo:IAO_0000119 "https://journals.aai.org/jimmunol/article/172/7/3994/71825/Cutting-Edge-CD96-Tactile-Promotes-NK-Cell-Target", "https://link.springer.com/article/10.1007/s00109-008-0433-0", "https://pubmed.ncbi.nlm.nih.gov/31988324/", "https://www.pnas.org/doi/abs/10.1073/pnas.93.6.2370", "https://www.pnas.org/doi/full/10.1073/pnas.95.14.8216", "https://www.sciencedirect.com/science/article/pii/B978012810514600009X?via%3Dihub" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "PVSRIPO vaccine vector" ; rdfs:subClassOf obo:VO_0000610 . obo:VO_0005435 obo:IAO_0000115 "A Comirnaty COVID-19 mRNA vaccine produced by Pfizer-BioNTech,which is a bivalent vaccine that is effective against the original strain of COVID-19 as well as the Omicron BA.1 variant.A non-US vaccine product." ; obo:IAO_0000117 "Penny Pan, Oliver He" ; obo:IAO_0000118 "Comirnaty Bivalent" ; obo:IAO_0000119 "PMID: 36541943", "https://secure.medicalletter.org/TML-article-1665f", "https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx" ; obo:VO_0003099 "Comirnaty" ; obo:VO_0005438 "520" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Authorized by WHO 10/19/2022 - Counted toward immunity in US.Ref:https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx" ; rdfs:label "SARS-COV-2 COVID-19 mRNA, bivalent, original/Omicron BA.1, Non-US Vaccine Product (Comirnaty Bivalent), Pfizer-BioNTech" ; rdfs:subClassOf obo:VO_0004987 . obo:VO_0005436 obo:IAO_0000115 "A Comirnaty COVID-19 mRNA vaccine utilizes Lipid Nanoparticle-Self-amplifying RNA technology, available as a bivalent boosters against the original strain of COVID-19 as well as the Omicron BA.1 variant produced by Pfizer (PF) with a dose of 30 mcg/0.3 mL to provide enhanced protection." ; obo:IAO_0000117 "Penny Pan, Oliver He" ; obo:IAO_0000119 "PMID: 36206167", "https://secure.medicalletter.org/TML-article-1660c", "https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx" ; obo:VO_0003099 "Comirnaty" ; obo:VO_0005438 "300" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "EUA authorized Pfizer adult bivalent booster ages 12+ yrs, original strain + omicron BA.4/BA.5. Not Authorized by WHO. Non-US Tradename for same formulation (Comirnaty Bivalent) counted toward immunity in US. Ref:https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx" ; rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, bivalent booster, preservative free, 30 mcg/0.3 mL dose, tris-sucrose formulation" ; rdfs:subClassOf obo:VO_0004987 . obo:VO_0005437 obo:IAO_0000115 "A Comirnaty COVID-19 mRNA vaccine utilizing Lipid Nanoparticle-Self-amplifying RNA technology against the original strain of COVID-19 without preservative ,which is produced by Pfizer (PF) with a dose of 30 mcg/0.3 mL." ; obo:IAO_0000117 "Penny Pan, Oliver He" ; obo:IAO_0000119 "https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx" ; obo:VO_0005438 "208" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine, mRNA, spike protein, LNP, preservative free, 30 mcg/0.3mL dose" ; rdfs:subClassOf obo:VO_0004987 . obo:VO_0005438 obo:IAO_0000115 "An annotation property that refers to a specific CVX ID." ; obo:IAO_0000117 "Oliver He", "Penny Pan" ; obo:IAO_0000119 "https://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cvx" ; a owl:AnnotationProperty ; rdfs:label "CVX code" . obo:VO_0005439 obo:IAO_0000115 "Passive vaccine is a vaccine that is made of immune globulin and used to immulize an individual against some dieases." ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "passive vaccine" ; rdfs:subClassOf obo:VO_0005505 . obo:VO_0005440 obo:IAO_0000118 "anthrax immune globulin" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "anthrax immune globulin passive vaccine" ; rdfs:seeAlso "CVX code:181" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005441 obo:IAO_0000118 "CMVIG" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cytomegalovirus immune globulin passive vaccine, intravenous" ; rdfs:seeAlso "CVX code:29" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005442 obo:IAO_0000115 """Hepatitis A Immune Globulin passive vaccine is a passive vaccine that provides protection against hepatitis A through the passive transfer of an antibody. Hep A, IG provides temporary immunity to the virus for two to three months, if administered prior to exposure or within two weeks after exposure.""" ; obo:IAO_0000118 "Hep A,IG", "Hepatitis A immune globulin" ; obo:IAO_0000119 """Stapleton, Jack T. \"Passive immunization against hepatitis A.\" Vaccine 10 (1992): S45-S47.""" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A immune globulin passive vaccine" ; rdfs:seeAlso "CVX code:154" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005443 obo:IAO_0000118 "HBIG", "hepatitis B immune globulin" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis B immune globulin passive vaccine" ; rdfs:seeAlso "CVX code:30" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005444 obo:IAO_0000118 "IG" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "immune globulin, intramuscular" ; rdfs:seeAlso "CVX code:86" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005445 obo:IAO_0000118 "IGIV" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "immune globulin, intravenous" ; rdfs:seeAlso "CVX code:87" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005446 obo:IAO_0000118 "IG,unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "immune globulin, unspecified formulation" ; rdfs:seeAlso "CVX code:14" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005447 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rabies immune globulin" ; rdfs:seeAlso "CVX code:34" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005448 obo:IAO_0000118 "RSV-IGIV", "respiratory syncytial virus immune globulin, intravenous" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "respiratory syncytial virus immune globulin passive vaccine, intravenous" ; rdfs:seeAlso "CVX code:71" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005449 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rho(D) Immune globulin - IM" ; rdfs:seeAlso "CVX code:157" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005450 obo:IAO_0000118 "Rho(D) Immune globulin- IV or IM" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rho(D) Immune globulin- IV or IM passive vaccine" ; rdfs:seeAlso "CVX code:156" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005451 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rho(D) Unspecified formulation" ; rdfs:seeAlso "CVX code:159" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005452 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus immune globulin" ; rdfs:seeAlso "CVX code:13" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005453 obo:IAO_0000118 "vaccinia immune globulin" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccinia immune globulin passive vaccine" ; rdfs:seeAlso "CVX code:79" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005454 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "varicella zoster immune globulin" ; rdfs:seeAlso "CVX code:36" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005455 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "varicella zoster immune globulin (Investigational New Drug)" ; rdfs:seeAlso "CVX code:117" ; rdfs:subClassOf obo:VO_0005439 . obo:VO_0005456 obo:IAO_0000118 "DTP-hepB-Hib plentavalent Non-US" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria-Pertussis-Tetanus-Haemophilus B-Hepatitis B vaccine,(Pentavalent)" ; rdfs:seeAlso "CVX code:198" ; rdfs:subClassOf obo:VO_0000738, obo:VO_0000746, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_10407 obo:VO_0000741 ) ] ] . obo:VO_0005457 obo:IAO_0000118 "DTP-Hib-Hep B" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DTP--Haemophilus influenzae type b conjugate and hepatitis B vaccine" ; rdfs:seeAlso "CVX code:107" ; rdfs:subClassOf obo:VO_0000738, obo:VO_0000746, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_10407 obo:VO_0000741 ) ] ] . obo:VO_0005458 obo:IAO_0000117 "YY, YH" ; obo:IAO_0000118 "Influenza, injectable, MDCK, quadrivalent, preservative" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza, injectable,Influenza, injectable, Madin Darby Canine Kidney, quadrivalent with preservative Madin Darby Canine Kidney, quadrivalent with preservative" ; rdfs:seeAlso "CVX code:186" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0005459 obo:IAO_0000118 "DTP,unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria, tetanus toxoids and acellular pertussis vaccine, unspecified formulation" ; rdfs:seeAlso "CVX code:107" ; rdfs:subClassOf obo:VO_0000738, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005460 obo:IAO_0000118 "DTP-Hib" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DTP--Haemophilus influenzae type b conjugate vaccine" ; rdfs:seeAlso "CVX code:22" ; rdfs:subClassOf obo:VO_0000662, obo:VO_0000738, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] . obo:VO_0005461 obo:IAO_0000115 "A viral vaccine that protects against infection with influenza virus and with high-dose seasonal,quadrivalent,0.7ml dose,preservative free." ; obo:IAO_0000117 "PY,HY" ; obo:IAO_0000118 "Influenza,high-dose,quadrivalent" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza,high-dose seasonal,quadrivalent,0.7ml dose,preservative free" ; rdfs:seeAlso "CVX code:197" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0005462 obo:IAO_0000117 "YY, YH" ; obo:IAO_0000118 "Influenza, injectable,quadrivalent, preservative free, pediatric" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza, injectable,quadrivalent, preservative free, pediatric" ; rdfs:seeAlso "CVX code:161" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0005463 obo:IAO_0000117 "YY, YH" ; obo:IAO_0000118 "influenza, intradermal, quadrivalent, preservative free" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza, injectable, MDCK, quadrivalent, preservative" ; rdfs:seeAlso "CVX code:166" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0005464 obo:IAO_0000115 "A poliovirus vaccine that contains two types of poliovirus and uses poliovirus particles that have been grown under controlled conditions and then killed to prevent disease caused from the vaccine." ; obo:IAO_0000117 "YY,YH" ; obo:IAO_0000118 "OPV bivalent" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Non-US bivalent oral polio vaccine (types 1 and 3)" ; rdfs:seeAlso "CXX code:178" ; rdfs:subClassOf obo:VO_0000664, [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005465 obo:IAO_0000115 "A poliovirus vaccine that contains one type of poliovirus and uses poliovirus particles that have been grown under controlled conditions and then killed to prevent disease caused from the vaccine." ; obo:IAO_0000117 "YY,YH" ; obo:IAO_0000118 "OPV ,monovalent, unspecified" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Non-US monovalent oral polio vaccine, unspecified formulation" ; rdfs:seeAlso "CXX code:179" ; rdfs:subClassOf obo:VO_0000664, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005466 obo:IAO_0000117 "YH, YY" ; obo:IAO_0000118 "Td (adult), 2 Lf tetanus toxoid, preservative free, adsorbed" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus and diphtheria toxoids, adsorbed, preservative free, for adult use (2 Lf of tetanus toxoid and 2 Lf of diphtheria toxoid)" ; rdfs:seeAlso "CVX code:09" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0005467 obo:IAO_0000117 "YH, YY" ; obo:IAO_0000118 "Td, adsorbed, preservative free, adult use, Lf unspecified" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus and diphtheria toxoids, adsorbed, preservative free, for adult use, Lf unspecified" ; rdfs:seeAlso "CVX code:196" ; rdfs:subClassOf obo:VO_0000732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0005468 obo:IAO_0000117 "YH, YY" ; obo:IAO_0000118 "Td (adult)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus and diphtheria toxoids, not adsorbed, for adult use" ; rdfs:seeAlso "CVX code:138" ; rdfs:subClassOf obo:VO_0000732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005469 obo:IAO_0000115 "A poliovirus vaccine that contains three types of poliovirus and uses poliovirus particles that have been grown under controlled conditions and then killed to prevent disease caused from the vaccine." ; obo:IAO_0000117 "YY,YH" ; obo:IAO_0000118 "OPV" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "trivalent poliovirus vaccine, live, oral" ; rdfs:seeAlso "CXX code:02" ; rdfs:subClassOf obo:VO_0000664, [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0005470 obo:IAO_0000117 "YY,YH" ; obo:IAO_0000118 "DTaP,IPV,Hib,HepB" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus, Haemophilus b Conjugate (Meningococcal Protein Conjugate), and Hepatitis B (Recombinant) Vaccine." ; rdfs:seeAlso "CVX code:146" ; rdfs:subClassOf obo:VO_0000662, obo:VO_0000732, obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_520 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:VO_0000741 [ a owl:Class ; owl:unionOf (obo:NCBITaxon_12080 obo:NCBITaxon_12083 obo:NCBITaxon_12086 ) ] ) ] ] . obo:VO_0005471 obo:IAO_0000115 "A vaccine adjuvant 30:70 (w/w) Water-in-Oil (W/O) emulsion that stimulates a mixed Th1/Th2 response." ; obo:IAO_0000116 """Chemical Nature: emulsion Mechanism of Action: adjuvanted antigen depot at injection site Immune profile induced: Mixed Th1/Th2 Route of immunization: IM and SQ Point of Contact: Peter Blackburn, MerciaPharma Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=23595760 https://www.ncbi.nlm.nih.gov/pubmed/?term=24783964 https://www.ncbi.nlm.nih.gov/pubmed/?term=34429319 https://www.ncbi.nlm.nih.gov/pubmed/?term=34926305 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT02500680 https://clinicaltrials.gov/ct2/show/NCT02500680 https://clinicaltrials.gov/ct2/show/NCT03624062 https://clinicaltrials.gov/ct2/show/NCT02118077""" ; obo:IAO_0000117 "Ari Joffe", "Oliver He", "Peter Blackburn", "Wolfgang Leitner" ; obo:IAO_0000118 "MAS-1" ; obo:IAO_0000119 "https://clinicaltrials.gov/ct2/show/NCT02118077", "https://clinicaltrials.gov/ct2/show/NCT02500680", "https://clinicaltrials.gov/ct2/show/NCT03624062", "https://vac.niaid.nih.gov/view?id=68", "https://www.ncbi.nlm.nih.gov/pubmed/?term=23595760", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24783964", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34429319", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34926305" ; obo:VO_0005328 "68" ; a owl:Class ; rdfs:label "MAS-1 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0005472 obo:IAO_0000115 "A vaccine adjuvant that induces CD8 T cells and provides innate protection." ; obo:IAO_0000116 """Chemical Nature: small molecule Mechanism of Action: Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: SQ Point of Contact: Taegyan Kang, Progeneer Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=36635335 Ongoing clinical trials: n/a""" ; obo:IAO_0000117 "Ari Joffe", "Oliver He", "Taegyan Kang", "Wolfgang Leitner" ; obo:IAO_0000118 "ProLNG-S" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=34", "https://www.ncbi.nlm.nih.gov/pubmed/?term=36635335" ; obo:VO_0005328 "34" ; a owl:Class ; rdfs:label "ProLNG-S vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005473 obo:IAO_0000115 "A vaccine adjuvant that is a lipid-based vaccine adjuvent based on cationic surfactant dimethyl-dioctadecyl ammonium (DDA) combined with C-type lectin agonist monomycoloyl glycerol (MMG) and TLR3 agonist poly I:C. CAF09b is able to induce CD8+ T-cell response." ; obo:IAO_0000116 """Chemical Nature: Liposome Mechanism of Action: n/a Immune profile induced: n/a Route of immunization: IN, IP, IM, Point of Contact: Gabriel Kristian Pedersen, Staten Serum Institute (SSI) Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=35163772 https://www.ncbi.nlm.nih.gov/pubmed/?term=33352684 https://www.ncbi.nlm.nih.gov/pubmed/?term=35036074 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT03715985""" ; obo:IAO_0000117 "Ari Joffe", "Gabriel Kristian Pedersen", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "CAF09b" ; obo:IAO_0000119 "https://clinicaltrials.gov/ct2/show/NCT03715985", "https://vac.niaid.nih.gov/view?id=76", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33352684", "https://www.ncbi.nlm.nih.gov/pubmed/?term=35036074", "https://www.ncbi.nlm.nih.gov/pubmed/?term=35163772" ; obo:VO_0005328 "76" ; a owl:Class ; rdfs:label "CAF09b vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005474 obo:IAO_0000115 "A vaccine adjuvant that is a lipid-based nanosuspension of a synthetic TLR7/8 ligand that facilitates adsorption to aluminum oxyhydroxide via the structural properties of the helper lipid employed." ; obo:IAO_0000116 """Chemical Nature: Small molecule Mechanism of Action: Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Valerie Soza, AAHI Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=27847326 https://www.ncbi.nlm.nih.gov/pubmed/?term=27847326 https://www.ncbi.nlm.nih.gov/pubmed/?term=36274085 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT04177355 https://clinicaltrials.gov/ct2/show/NCT05781542 https://clinicaltrials.gov/ct2/show/NCT05471076 https://clinicaltrials.gov/ct2/show/NCT04915768 https://clinicaltrials.gov/ct2/show/NCT05781542""" ; obo:IAO_0000117 "Ari Joffe", "Oliver He", "Valerie Soza", "Wolfgang Leitner" ; obo:IAO_0000118 "3M-052-AF" ; obo:IAO_0000119 "https://clinicaltrials.gov/ct2/show/NCT04177355", "https://clinicaltrials.gov/ct2/show/NCT04915768", "https://clinicaltrials.gov/ct2/show/NCT05471076", "https://clinicaltrials.gov/ct2/show/NCT05781542", "https://vac.niaid.nih.gov/view?id=69", "https://www.ncbi.nlm.nih.gov/pubmed/?term=27847326", "https://www.ncbi.nlm.nih.gov/pubmed/?term=36274085" ; obo:VO_0005328 "69" ; a owl:Class ; rdfs:label "3M-052-AF vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005475 obo:IAO_0000115 "A vaccine adjuvant that reformulates Alhydrogel as a stable nanoparticle with the anionic polymer polyacrylic acid (PAA), leading to the induction of structure-dependent TH1 response." ; obo:IAO_0000116 """Chemical Nature: Small molecule Mechanism of Action: Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Valerie Soza, AAHI Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=30622742 https://www.ncbi.nlm.nih.gov/pubmed/?term=31930264""" ; obo:IAO_0000117 "Ari Joffe", "Oliver He", "Valerie Soza", "Wolfgang Leitner" ; obo:IAO_0000118 "NanoAlum" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=71", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30622742", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31930264" ; obo:VO_0005328 "71" ; a owl:Class ; rdfs:label "NanoAlum vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005476 obo:IAO_0000115 "A vaccine adjuvant is a small molecule adjuvant that induces Th1-based immune response and is designed for use with self-amplifying RNA antigens." ; obo:IAO_0000116 """Chemical Nature: Small molecule Mechanism of Action: Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Valerie Soza, AAHI Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=35911728 https://www.ncbi.nlm.nih.gov/pubmed/?term=24551202 https://www.ncbi.nlm.nih.gov/pubmed/?term=34058388 https://www.ncbi.nlm.nih.gov/pubmed/?term=35308783 https://www.ncbi.nlm.nih.gov/pubmed/?term=36589712 https://www.ncbi.nlm.nih.gov/pubmed/?term=36323666 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT05370040""" ; obo:IAO_0000117 "Ari Joffe", "Oliver He", "Valerie Soza", "Wolfgang Leitner" ; obo:IAO_0000118 "NLC vaccine adjuvant", "Nanostructured Lipid Carrier", "Nanostructured Lipid Carrier (NLC)" ; obo:IAO_0000119 "https://clinicaltrials.gov/ct2/show/NCT05370040", "https://vac.niaid.nih.gov/view?id=70", "https://www.ncbi.nlm.nih.gov/pubmed/?term=24551202", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34058388", "https://www.ncbi.nlm.nih.gov/pubmed/?term=35308783", "https://www.ncbi.nlm.nih.gov/pubmed/?term=35911728", "https://www.ncbi.nlm.nih.gov/pubmed/?term=36323666", "https://www.ncbi.nlm.nih.gov/pubmed/?term=36589712" ; obo:VO_0005328 "70" ; a owl:Class ; rdfs:label "Nanostructured Lipid Carrier (NLC) vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005477 obo:IAO_0000117 "AH" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Giardia spp. protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0005478 oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PFS25/28 in Matrix M" ; rdfs:subClassOf obo:VO_0000087, obo:VO_0000534, obo:VO_0005502, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000524 ; owl:someValuesFrom obo:VO_0010053 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000249 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005561 ; owl:someValuesFrom obo:NCBITaxon_5833 ], [ a owl:Restriction ; owl:onProperty obo:VO_0005562 ; owl:someValuesFrom obo:NCBITaxon_7164 ] . obo:VO_0005479 obo:IAO_0000115 "a malaria vaccine that protects against malaria caused by Plasmodium knowlesi." ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Plasmodium knowlesi vaccine" ; rdfs:subClassOf obo:VO_0000761 . obo:VO_0005480 obo:IAO_0000115 "a malaria vaccine that protects against malaria caused by Plasmodium chabaudi." ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Plasmodium chabaudi vaccine" ; rdfs:subClassOf obo:VO_0000761 . obo:VO_0005481 obo:IAO_0000115 "A relation between a material entity and a parasite where the material entity causes some processagainst some parasite such that transmitting to additional hosts or vectors." ; a owl:ObjectProperty ; rdfs:label "capable of blocking transmission (of life cycle)" . obo:VO_0005482 obo:IAO_0000115 "A vaccine adjuvant is an oil-in-water emulsion that induces Th1-based immune response." ; obo:IAO_0000116 """Chemical Nature: Small molecule Mechanism of Action: Innate Immune Activation Immune profile induced: n/a Route of immunization: IM Point of Contact: Valerie Soza, AAHI Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=32983577 https://www.ncbi.nlm.nih.gov/pubmed/?term=35459225""" ; obo:IAO_0000117 "Ari Joffe", "Oliver He", "Valerie Soza", "Wolfgang Leitner" ; obo:IAO_0000118 "SLA-AF" ; obo:IAO_0000119 "https://vac.niaid.nih.gov/view?id=72", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32983577", "https://www.ncbi.nlm.nih.gov/pubmed/?term=35459225" ; obo:VO_0005328 "72" ; a owl:Class ; rdfs:label "SLA-AF vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0005483 obo:IAO_0000115 "A vaccine adjuvant is a gadoteridol-loaded cationic adjuvant formulation 01 that induced a Th1/Th17 type of immune response." ; obo:IAO_0000116 """Chemical Nature: Liposome system Mechanism of Action: n/a Immune profile induced: Th1/Th17 Route of immunization: IP, IM, IN, SQ, ID, SC, SL, intratracheal, endotracheal, Fish vaccination Point of Contact: Gabriel Kristian Pedersen, Staten Serum Institute (SSI) Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=31539263 https://www.ncbi.nlm.nih.gov/pubmed/?term=30555488 https://www.ncbi.nlm.nih.gov/pubmed/?term=29699790 https://www.ncbi.nlm.nih.gov/pubmed/?term=34044110 https://www.ncbi.nlm.nih.gov/pubmed/?term=26394776 https://www.ncbi.nlm.nih.gov/pubmed/?term=18776936 https://www.ncbi.nlm.nih.gov/pubmed/?term=30291987 https://www.ncbi.nlm.nih.gov/pubmed/?term=21124731 https://www.ncbi.nlm.nih.gov/pubmed/?term=29358939 https://www.ncbi.nlm.nih.gov/pubmed/?term=33072125 https://www.ncbi.nlm.nih.gov/pubmed/?term=35585969 https://www.ncbi.nlm.nih.gov/pubmed/?term=26494626 https://www.ncbi.nlm.nih.gov/pubmed/?term=26379666 https://www.ncbi.nlm.nih.gov/pubmed/?term=35124896 https://www.ncbi.nlm.nih.gov/pubmed/?term=34358167 https://www.ncbi.nlm.nih.gov/pubmed/?term=29541075 https://www.ncbi.nlm.nih.gov/pubmed/?term=31130946 https://www.ncbi.nlm.nih.gov/pubmed/?term=31906072 https://www.ncbi.nlm.nih.gov/pubmed/?term=32106599 https://www.ncbi.nlm.nih.gov/pubmed/?term=19492047 https://www.ncbi.nlm.nih.gov/pubmed/?term=33422991 https://www.ncbi.nlm.nih.gov/pubmed/?term=28414746 https://www.ncbi.nlm.nih.gov/pubmed/?term=33066267 https://www.ncbi.nlm.nih.gov/pubmed/?term=27958370 https://www.ncbi.nlm.nih.gov/pubmed/?term=23308247 https://www.ncbi.nlm.nih.gov/pubmed/?term=30984200 https://www.ncbi.nlm.nih.gov/pubmed/?term=20505822 https://www.ncbi.nlm.nih.gov/pubmed/?term=27525651 https://www.ncbi.nlm.nih.gov/pubmed/?term=23873630 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT00922363 https://clinicaltrials.gov/ct2/show/NCT01009762 https://clinicaltrials.gov/ct2/show/NCT02787109 https://clinicaltrials.gov/ct2/show/NCT01141205 https://clinicaltrials.gov/ct2/show/NCT03926728""" ; obo:IAO_0000117 "Ari Joffe", "Gabriel Kristian Pedersen", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "CAF01" ; obo:IAO_0000119 "https://clinicaltrials.gov/ct2/show/NCT00922363", "https://clinicaltrials.gov/ct2/show/NCT01009762", "https://clinicaltrials.gov/ct2/show/NCT01141205", "https://clinicaltrials.gov/ct2/show/NCT02787109", "https://clinicaltrials.gov/ct2/show/NCT03926728", "https://vac.niaid.nih.gov/view?id=75", "https://www.ncbi.nlm.nih.gov/pubmed/?term=18776936", "https://www.ncbi.nlm.nih.gov/pubmed/?term=21124731", "https://www.ncbi.nlm.nih.gov/pubmed/?term=26394776", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29358939", "https://www.ncbi.nlm.nih.gov/pubmed/?term=29699790", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30291987", "https://www.ncbi.nlm.nih.gov/pubmed/?term=30555488", "https://www.ncbi.nlm.nih.gov/pubmed/?term=31539263", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34044110" ; obo:VO_0005328 "75" ; a owl:Class ; rdfs:label "CAF01 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005314 ] . obo:VO_0005484 obo:IAO_0000115 "A cancer vaccine that is developed against breast cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "breast cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ] . obo:VO_0005485 obo:IAO_0000115 "A cancer vaccine that is developed against bladder cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "bladder cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ] . obo:VO_0005486 obo:IAO_0000115 "A cancer vaccine that is developed against lung cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "lung cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ] . obo:VO_0005487 obo:IAO_0000115 "A cancer vaccine that is developed against leukemia." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "leukemia cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ] . obo:VO_0005488 obo:IAO_0000115 "A cancer vaccine that is developed against cervical cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "cervical cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ] . obo:VO_0005489 obo:IAO_0000115 "A cancer vaccine that is developed against colon cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "colon cancer vaccine" ; rdfs:subClassOf obo:VO_0005426, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ] . obo:VO_0005490 obo:IAO_0000115 "A cancer vaccine that is developed against gastric cancer" ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "gastric cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10534 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10534 ] . obo:VO_0005491 obo:IAO_0000115 "A cancer vaccine that is developed against mesothelioma cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "mesothelioma cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:MONDO_0005065 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:MONDO_0005065 ] . obo:VO_0005492 obo:IAO_0000115 "A cancer vaccine that is developed against myeloma cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "myeloma cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ] . obo:VO_0005493 obo:IAO_0000115 "A cancer vaccine that is developed against ovarian cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "ovarian cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ] . obo:VO_0005494 obo:IAO_0000115 "A cancer vaccine that is developed against renal cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "renal cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ] . obo:VO_0005495 obo:IAO_0000115 "A cancer vaccine that is developed against sarcoma cancer." ; obo:IAO_0000117 "Oliver He" ; a owl:Class ; rdfs:label "sarcoma cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ] . obo:VO_0005496 obo:IAO_0000115 "A cancer vaccine that is developed against esophageal cancer." ; obo:IAO_0000117 "Jie Zheng", "Oliver He", "Xingxian Li", "Yuying Pan" ; a owl:Class ; rdfs:label "esophageal cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5041 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5041 ] . obo:VO_0005497 obo:IAO_0000115 "A cancer vaccine that is developed against head and neck cancer." ; obo:IAO_0000117 "Jie Zheng", "Oliver He", "Xingxian Li", "Yuying Pan" ; a owl:Class ; rdfs:label "head and neck cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11934 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11934 ] . obo:VO_0005498 obo:IAO_0000115 "A cancer vaccine that is developed against nasopharyngeal cancer." ; obo:IAO_0000117 "Jie Zheng", "Oliver He", "Xingxian Li", "Yuying Pan" ; a owl:Class ; rdfs:label "nasopharyngeal cancer vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9261 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9261 ] . obo:VO_0005499 obo:IAO_0000115 "A cancer vaccine that is developed against hepatocellular carcinoma." ; obo:IAO_0000117 "Jie Zheng", "Oliver He", "Xingxian Li", "Yuying Pan" ; a owl:Class ; rdfs:label "hepatocellular carcinoma vaccine" ; rdfs:subClassOf obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_684 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_684 ] . obo:VO_0005500 obo:IAO_0000115 "An annotation property that shows the status of vaccine developmeint including: clinical trial, research, licensed, or Emergency Use Authorization (EUA)." ; obo:IAO_0000117 "Anthony Huffman", "Jie Zheng", "Oliver He", "Penny Pan" ; a owl:AnnotationProperty ; rdfs:label "status of vaccine development" . obo:VO_0005501 obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum MSA2" ; rdfs:subClassOf obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000130 ] . obo:VO_0005502 obo:IAO_0000115 "A transmision blocking is a vaccine that prevents or reduce the transmission of a disorder within a target host or among a population by inducing or modifying specific adaptive immune responses against the antigens present in the vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "transmission blocking vaccine" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0005503 obo:IAO_0000115 "a grouping class for vaccines for specific diseases" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccine for disease" ; rdfs:subClassOf obo:VO_0000001, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4 ] . obo:VO_0005504 obo:IAO_0000115 "a grouping class for vaccines for specific pathogens" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccine for pathogen" ; rdfs:subClassOf obo:VO_0000001, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OBI_0100026 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000718 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:OBI_0100026 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:OBI_0000718 ] ) ] ] . obo:VO_0005505 obo:IAO_0000115 "a grouping class for vaccines for specific platforms" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccine by platform type" ; rdfs:subClassOf obo:VO_0000001 . obo:VO_0005561 obo:IAO_0000115 "A relation between a vaccine and a parasite where the vaccine immunizes against some parasite such that transmitting to additional hosts or vectors." ; a owl:ObjectProperty ; rdfs:label "blocks transmission of pathogen via vaccine" ; rdfs:subPropertyOf obo:VO_0003355, obo:VO_0005481 . obo:VO_0005562 obo:IAO_0000115 "A relation between a vaccine X and organism Y where the vaccine X generates an immune response in a vaccinated organism and the immune product (e.g., antibody) can be transferred to the organism Y" ; a owl:ObjectProperty ; rdfs:label "vaccine immunity response transferrable to organism" . obo:VO_0005563 obo:IAO_0000115 "A vaccine that targets against a microbial eukaryote caused disease." ; obo:IAO_0000117 "Anthony Huffman, Jie Zheng, Oliver He" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "microbial eukaryotic vaccine" ; rdfs:subClassOf obo:VO_0005504 . obo:VO_0005800 obo:IAO_0000115 "A Inactivated vaccine that immunizes against Neospora caninum protozoa." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:1975" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. caninum Killed Protozoa Vaccine" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_29176 ] . obo:VO_0005801 obo:IAO_0000115 "A Inactivated vaccine that immunizes against Toxoplasma gondii trypmastigote." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:6065" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "CTLVECNS" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0005802 obo:IAO_0000115 "A Live attenuated vaccine encoding a1-giardin and CWP2 that immunizes against Giardi lamblia trophozoite." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:5993" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "G. lamblia bivalent DNA vaccine encoding a1-giardin and CWP2" ; rdfs:subClassOf obo:VO_0001083, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5741 ] . obo:VO_0005803 obo:IAO_0000115 "A Live attenuated vaccine encoding a-enolase that immunizes against Giardi lamblia trophozoite." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:5991" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "G. lamblia vaccine encoding a-enolase" ; rdfs:subClassOf obo:VO_0001083, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5741 ] . obo:VO_0005804 obo:IAO_0000115 "A Live attenuated vaccine encoding a1-giardin that immunizes against Giardi lamblia trophozoite." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:5989" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "G. lamblia vaccine encoding a1-giardin" ; rdfs:subClassOf obo:VO_0001083, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5741 ] . obo:VO_0005805 obo:IAO_0000115 "A Live attenuated vaccine expressing VSPH7 that immunizes against Giardi lamblia trophozoite." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:6004" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "G. lamblia vaccine using attenuated Salmonella vaccine expressing VSPH7" ; rdfs:subClassOf obo:VO_0001083, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5741 ] . obo:VO_0005806 obo:IAO_0000115 "A Live attenuated vaccine p52(-)/p36(-) GAP that immunizes against Plasmodium falciparum sporozoite." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:5952" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "p52(-)/p36(-) GAP" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000137 ] . obo:VO_0005807 obo:IAO_0000115 "A Live attenuated vaccine Pb(PfCS@UIS4) that immunizes against Plasmodium falciparum sporozoite." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:5988" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pb(PfCS@UIS4)" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000137 ] . obo:VO_0005808 obo:IAO_0000115 "A Live attenuated vaccine PfSPZ that immunizes against Plasmodium falciparum sporozoite." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:5950" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PfSPZ" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000137 ] . obo:VO_0005809 obo:IAO_0000115 "A Live attenuated vaccine RH-AMA1KO that immunizes against Toxoplasma gondii trypmastigote." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:6069" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "RH-AMA1KO" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0005810 obo:IAO_0000115 "A Live attenuated vaccine with GRA17 mutant that immunizes against Toxoplasma gondii trypmastigote." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:6082" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii GRA17 mutant vaccine" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0005811 obo:IAO_0000115 "A Live attenuated vaccine irradiated sterilised tachyzoites that immunizes against Toxoplasma gondii trypmastigote." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:6090" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii irradiated sterilised tachyzoites" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0005812 obo:IAO_0000115 "A Live attenuated vaccine with LDH1 and LDH2 mutant that immunizes against Toxoplasma gondii trypmastigote." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:6087" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii LDH1 and LDH2 mutant vaccine" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0005813 obo:IAO_0000115 "A Live attenuated vaccine with DSCG adjuvant that immunizes against Toxoplasma gondii trypmastigote." ; obo:IAO_0000117 "Anthony Huffman" ; obo:VO_0001818 "violinID:6091" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "UV-attenuated Toxoplasma gondii with DSCG adjuvant" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0006000 obo:IAO_0000118 "adenovirus unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "adenovirus vaccine unspecified formulation" ; rdfs:seeAlso "CVX:82" ; rdfs:subClassOf obo:VO_0000037, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10535 ] . obo:VO_0006001 obo:IAO_0000118 "botulinum antitoxin" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "botulinum antitoxin" ; rdfs:seeAlso "CVX:27" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0006002 obo:IAO_0000118 "cholera unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cholera vaccine unspecified formulation" ; rdfs:seeAlso "CVX:26" ; rdfs:subClassOf obo:VO_0000763, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_666 ] . obo:VO_0006003 obo:IAO_0000118 "cholera BivWC" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cholera BivWC" ; rdfs:seeAlso "CVX:173" ; rdfs:subClassOf obo:VO_0000763, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_666 ] . obo:VO_0006004 obo:IAO_0000118 "cholera live attenuated" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "cholera live attenuated" ; rdfs:seeAlso "CVX:174" ; rdfs:subClassOf obo:VO_0000763, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_666 ] . obo:VO_0006005 obo:IAO_0000118 "diphtheria antitoxin" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria antitoxin" ; rdfs:seeAlso "CVX:12" ; rdfs:subClassOf obo:VO_0000508, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1717 ] . obo:VO_0006006 obo:IAO_0000118 "Hib unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b vaccine conjugate unspecified formulation" ; rdfs:seeAlso "CVX:17" ; rdfs:subClassOf obo:VO_0000662, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] . obo:VO_0006007 obo:IAO_0000118 "Hib (PRP-D)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b vaccine PRP-D conjugate" ; rdfs:seeAlso "CVX:46" ; rdfs:subClassOf obo:VO_0000662, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:VO_0000741 ] . obo:VO_0006008 obo:IAO_0000118 "Hep A live attenuated" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hep A live attenuated-IM" ; rdfs:seeAlso "CVX:169" ; rdfs:subClassOf obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ] . obo:VO_0006009 obo:IAO_0000118 "Hep A adult" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis A vaccine adult dosage" ; rdfs:seeAlso "CVX:52" ; rdfs:subClassOf obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ] . obo:VO_0006010 obo:IAO_0000118 "Hep A pediatric unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis A vaccine pediatric dosage unspecified formulation" ; rdfs:seeAlso "CVX:31" ; rdfs:subClassOf obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ] . obo:VO_0006011 obo:IAO_0000118 "Hep A ped/adol 3 dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis A vaccine pediatric/adolescent dosage 3 dose schedule" ; rdfs:seeAlso "CVX:84" ; rdfs:subClassOf obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ] . obo:VO_0006012 obo:IAO_0000118 "Hep A unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis A vaccine unspecified formulation" ; rdfs:seeAlso "CVX:85" ; rdfs:subClassOf obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12092 ] . obo:VO_0006013 obo:IAO_0000118 "HepB recombinant 3-antigen Al(OH)3" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B vaccine (recombinant) 3-antigen Al(OH)3 adjuvanted" ; rdfs:seeAlso "CVX:220" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0006014 obo:IAO_0000118 "Hep B adolescent/high risk infant" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis B vaccine adolescent/high risk infant dosage" ; rdfs:seeAlso "CVX:42" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0006015 obo:IAO_0000118 "Hep B unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis B vaccine unspecified formulation" ; rdfs:seeAlso "CVX:45" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10407 ] . obo:VO_0006016 obo:IAO_0000118 "Hep C" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis C vaccine" ; rdfs:seeAlso "CVX:58" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052230 ] . obo:VO_0006017 obo:IAO_0000118 "Hep E" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "hepatitis E vaccine" ; rdfs:seeAlso "CVX:59" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1678143 ] . obo:VO_0006018 obo:IAO_0000118 "herpes simplex 2" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "herpes simplex virus type 2 vaccine" ; rdfs:seeAlso "CVX:60" ; rdfs:subClassOf obo:VO_0000727, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10310 ] . obo:VO_0006019 obo:IAO_0000118 "typhus historical" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Historical record of a typhus vaccination" ; rdfs:seeAlso "CVX:131" ; rdfs:subClassOf obo:VO_0000767, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_780 ] . obo:VO_0006020 obo:IAO_0000118 "HPV unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "HPV unspecified formulation" ; rdfs:seeAlso "CVX:137" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10566 ] . obo:VO_0006021 obo:IAO_0000118 "Rabies - IM Diploid cell culture" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human Rabies vaccine from human diploid cell culture" ; rdfs:seeAlso "CVX:175" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0006022 obo:IAO_0000118 "influenza nasal unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "influenza nasal unspecified formulation" ; rdfs:seeAlso "CVX:151" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0006023 obo:IAO_0000118 "influenza split (incl. purified surface antigen)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "influenza virus vaccine split virus (incl. purified surface antigen)-retired CODE" ; rdfs:seeAlso "CVX:15" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0006024 obo:IAO_0000118 "influenza unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "influenza virus vaccine unspecified formulation" ; rdfs:seeAlso "CVX:88" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0006025 obo:IAO_0000118 "influenza whole" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "influenza virus vaccine whole virus" ; rdfs:seeAlso "CVX:16" ; rdfs:subClassOf obo:VO_0000642, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11309 ] . obo:VO_0006026 obo:IAO_0000118 "Japanese Encephalitis unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese Encephalitis vaccine unspecified formulation" ; rdfs:seeAlso "CVX:129" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11072 ] . obo:VO_0006027 obo:IAO_0000118 "Junin virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Junin virus vaccine" ; rdfs:seeAlso "CVX:63" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2169991 ] . obo:VO_0006028 obo:IAO_0000118 "leprosy" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "leprosy vaccine" ; rdfs:seeAlso "CVX:65" ; rdfs:subClassOf obo:VO_0000592, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1769 ] . obo:VO_0006029 obo:IAO_0000118 "meningococcal A polysaccharide (non-US)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal A polysaccharide vaccine (non-US)" ; rdfs:seeAlso "CVX:191" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0006030 obo:IAO_0000118 "meningococcal AC polysaccharide (non-US)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal AC polysaccharide vaccine (non-US)" ; rdfs:seeAlso "CVX:192" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0006031 obo:IAO_0000118 "meningococcal ACWY unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal ACWY vaccine unspecified formulation" ; rdfs:seeAlso "CVX:108" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0006032 obo:IAO_0000118 "meningococcal B unspecified" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal B unspecified formulation" ; rdfs:seeAlso "CVX:164" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0006033 obo:IAO_0000118 "meningococcal C conjugate" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal C conjugate vaccine" ; rdfs:seeAlso "CVX:103" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0006034 obo:IAO_0000118 "meningococcal unknown serogroups" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal vaccine of unknown formulation and unknown serogroups" ; rdfs:seeAlso "CVX:167" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0006035 obo:IAO_0000118 "meningococcal polysaccharide (groups A C Y W-135) TT conjugate" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "meningococcal polysaccharide (groups A C Y W-135) tetanus toxoid conjugate vaccine 0.5mL dose preservative free" ; rdfs:seeAlso "CVX:203" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0006036 obo:IAO_0000118 "meningococcal MCV4 unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Meningococcal MCV4 unspecified conjugate formulation(groups A C Y and W-135)" ; rdfs:seeAlso "CVX:147" ; rdfs:subClassOf obo:VO_0000053, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_487 ] . obo:VO_0006037 obo:IAO_0000118 "Novel Influenza-H1N1-09 all formulations" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Novel influenza-H1N1-09 all formulations" ; rdfs:seeAlso "CVX:128" ; rdfs:subClassOf obo:VO_0000578, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ] . obo:VO_0006038 obo:IAO_0000118 "Novel influenza-H1N1-09" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Novel influenza-H1N1-09 injectable" ; rdfs:seeAlso "CVX:127" ; rdfs:subClassOf obo:VO_0000578, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ] . obo:VO_0006039 obo:IAO_0000118 "Novel Influenza-H1N1-09 nasal" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Novel Influenza-H1N1-09 live virus for nasal administration" ; rdfs:seeAlso "CVX:125" ; rdfs:subClassOf obo:VO_0000578, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ] . obo:VO_0006040 obo:IAO_0000118 "Novel influenza-H1N1-09 preservative-free" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Novel influenza-H1N1-09 preservative-free injectable" ; rdfs:seeAlso "CVX:126" ; rdfs:subClassOf obo:VO_0000578, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_114727 ] . obo:VO_0006041 obo:IAO_0000118 "Pneumococcal conjugate PCV15 polysaccharide CRM197 conjugate adjuvant PF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pneumococcal conjugate vaccine 15-valent (PCV15) polysaccharide CRM197 conjugate adjuvant preservative free" ; rdfs:seeAlso "CVX:215" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0006042 obo:IAO_0000118 "c conjugate PCV20 polysaccharide CRM197 conjugate adjuvant PF" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pneumococcal conjugate vaccine 20-valent (PCV20) polysaccharide CRM197 conjugate adjuvant preservative free" ; rdfs:seeAlso "CVX:216" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0006043 obo:IAO_0000118 "PCV10" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "pneumococcal conjugate vaccine 10 valent" ; rdfs:seeAlso "CVX:177" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0006044 obo:IAO_0000118 "Pneumococcal Conjugate unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Pneumococcal Conjugate unspecified formulation" ; rdfs:seeAlso "CVX:152" ; rdfs:subClassOf obo:VO_0000675, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1313 ] . obo:VO_0006045 obo:IAO_0000118 "rabies intradermal injection" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rabies vaccine for intradermal injection" ; rdfs:seeAlso "CVX:40" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0006046 obo:IAO_0000118 "rabies unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rabies vaccine unspecified formulation" ; rdfs:seeAlso "CVX:90" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11292 ] . obo:VO_0006047 obo:IAO_0000118 "RSV-MAb (new)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "respiratory syncytial virus monoclonal antibody (motavizumab) intramuscular" ; rdfs:seeAlso "CVX:145" ; rdfs:subClassOf obo:VO_0000753, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12814 ] . obo:VO_0006048 obo:IAO_0000118 "RSV-MAb" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "respiratory syncytial virus monoclonal antibody (palivizumab) intramuscular" ; rdfs:seeAlso "CVX:93" ; rdfs:subClassOf obo:VO_0000753, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12814 ] . obo:VO_0006049 obo:IAO_0000118 "rheumatic fever" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rheumatic fever vaccine" ; rdfs:seeAlso "CVX:72" ; rdfs:subClassOf obo:VO_0000772, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_36470 ] . obo:VO_0006050 obo:IAO_0000118 "rotavirus unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rotavirus vaccine unspecified formulation" ; rdfs:seeAlso "CVX:122" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] . obo:VO_0006051 obo:IAO_0000118 "rotavirus tetravalent" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "rotavirus live tetravalent vaccine" ; rdfs:seeAlso "CVX:74" ; rdfs:subClassOf obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10912 ] . obo:VO_0006052 obo:IAO_0000118 "COVID-19 D614 recomb preS dTM AS03 adjuvant add PF 10mcg/0.5mL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine D614 prefusion spike recombinant protein subunit (CoV2 preS dTM) AS03 adjuvant added preservative free 10mcg/0.5mL dose" ; rdfs:seeAlso "CVX:226" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006053 obo:IAO_0000118 "COVID-19 D614 recomb preS dTM AS03 adjuvant add PF 5mcg/0.5mL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine D614 prefusion spike recombinant protein subunit (CoV2 preS dTM) AS03 adjuvant added preservative free 5mcg/0.5mL dose" ; rdfs:seeAlso "CVX:225" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006054 obo:IAO_0000118 "COVID-19 mRNA LNP-S bivalent booster PF 10 mcg/0.2 mL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent booster preservative free 10 mcg/0.2 mL dose" ; rdfs:seeAlso "CVX:230" ; rdfs:subClassOf obo:VO_0005269, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006055 obo:IAO_0000118 "COVID-19 mRNA LNP-S bivalent booster PF 10 mcg/0.2 mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent booster preservative free 10 mcg/0.2 mL dose tris-sucrose formulation" ; rdfs:seeAlso "CVX:301" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006056 obo:IAO_0000118 "COVID-19 mRNA LNP-S bivalent booster PF 30 mcg/0.3 mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent booster preservative free 30 mcg/0.3 mL dose tris-sucrose formulation" ; rdfs:seeAlso "CVX:300" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006057 obo:IAO_0000118 "COVID-19 mRNA LNP-S bivalent booster PF 50 mcg/0.5 mL or 25mcg/0.25 mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent booster preservative free 50 mcg/0.5 mL or 25 mcg/0.25 mL dose" ; rdfs:seeAlso "CVX:229" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006058 obo:IAO_0000118 "COVID-19 mRNA LNP-S bivalent PF 3 mcg/0.2 mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP bivalent preservative free 3 mcg/0.2 mL dose tris-sucrose formulation" ; rdfs:seeAlso "CVX:302" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006059 obo:IAO_0000118 "COVID-19 mRNA LNP-S PF 10 mcg/0.2 mL dose tris-sucrose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 10 mcg/0.2mL dose tris-sucrose formulation" ; rdfs:seeAlso "CVX:218" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006060 obo:IAO_0000118 "COVID-19 mRNA LNP-S PF 100 mcg/0.5mL dose or 50 mcg/0.25mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 100 mcg/0.5mL dose or 50 mcg/0.25mL dose" ; rdfs:seeAlso "CVX:207" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006061 obo:IAO_0000118 "COVID-19 mRNA LNP-S PF 3 mcg/0.2 mL dose tris-sucrose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 3 mcg/0.2mL dose tris-sucrose formulation" ; rdfs:seeAlso "CVX:219" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006062 obo:IAO_0000118 "COVID-19 mRNA LNP-S PF 30 mcg/0.3 mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 30 mcg/0.3mL dose" ; rdfs:seeAlso "CVX:208" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006063 obo:IAO_0000118 "COVID-19 mRNA LNP-S PF 30 mcg/0.3 mL dose tris-sucrose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 30 mcg/0.3mL dose tris-sucrose formulation" ; rdfs:seeAlso "CVX:217" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006064 obo:IAO_0000118 "COVID-19 mRNA LNP-S PF 50 mcg/0.5 mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free 50 mcg/0.5 mL dose" ; rdfs:seeAlso "CVX:221" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006065 obo:IAO_0000118 "COVID-19 mRNA LNP-S PF pediatric 25 mcg/0.25 mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free pediatric 25 mcg/0.25 mL dose" ; rdfs:seeAlso "CVX:228" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006066 obo:IAO_0000118 "COVID-19 mRNA LNP-S PF pediatric 50 mcg/0.5 mL dose" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine mRNA spike protein LNP preservative free pediatric 50 mcg/0.5 mL dose" ; rdfs:seeAlso "CVX:227" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006067 obo:IAO_0000118 "SARS-COV-2 (COVID-19) vaccine UNSPECIFIED" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 (COVID-19) vaccine UNSPECIFIED" ; rdfs:seeAlso "CVX:213" ; rdfs:subClassOf obo:VO_0004908, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006068 obo:IAO_0000118 "COVID-19 mRNA bivalent original/Omicron BA.1 Non-US Vaccine (Spikevax Bivalent) Moderna" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 COVID-19 mRNA bivalent original/Omicron BA.1 Non-US Vaccine (Spikevax Bivalent) Moderna" ; rdfs:seeAlso "CVX:519" ; rdfs:subClassOf obo:VO_0004908, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006069 obo:IAO_0000118 "COVID-19 mRNA bivalent original/Omicron BA.1 Non-US Vaccine Product Pfizer-BioNTech" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 COVID-19 mRNA bivalent original/Omicron BA.1 Non-US Vaccine Product (Comirnaty Bivalent) Pfizer-BioNTech" ; rdfs:seeAlso "CVX:520" ; rdfs:subClassOf obo:VO_0005265, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006070 obo:IAO_0000118 "COVID-19 Non-US Vaccine Product Unknown" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 COVID-19 Non-US Vaccine Specific Product Unknown" ; rdfs:seeAlso "CVX:500" ; rdfs:subClassOf obo:VO_0004908, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006071 obo:IAO_0000118 "COVID-19 PS Non-US Vaccine (Jiangsu Province Centers for Disease Control and Prevention)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Jiangsu Province Centers for Disease Control and Prevention)" ; rdfs:seeAlso "CVX:508" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006072 obo:IAO_0000118 "COVID-19 PS Non-US Vaccine (Anhui Zhifei Longcom Biopharm + Inst of Micro Chinese Acad of Sciences)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Anhui Zhifei Longcom Biopharmaceutical + Institute of Microbiology Chinese Academy of Sciences)" ; rdfs:seeAlso "CVX:507" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006073 obo:IAO_0000118 "SARS-COV-2 COVID-19 PS Non-US Vaccine (Anhui Zhifei Longcom Zifivax)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 COVID-19 Protein Subunit Non-US Vaccine Product (Anhui Zhifei Longcom Zifivax)" ; rdfs:seeAlso "CVX:513" ; rdfs:subClassOf obo:VO_0005202, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006074 obo:IAO_0000118 "COVID-19 VVnr Non-US Vaccine (CanSino Biological Inc./Beijing Institute of Biotechnology" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 COVID-19 Viral Vector Non-replicating Non-US Vaccine Product (CONVIDECIA) CanSino Biological Inc./Beijing Institute of Biotechnology" ; rdfs:seeAlso "CVX:506" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006075 obo:IAO_0000118 "COVID-19 VVnr Non-US Vaccine (Sputnik Light)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS-COV-2 COVID-19 Viral Vector Non-replicating Non-US Vaccine Product (Sputnik Light)" ; rdfs:seeAlso "CVX:504" ; rdfs:subClassOf obo:VO_0005199, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_2697049 ] . obo:VO_0006076 obo:IAO_0000118 "tetanus toxoid not adsorbed" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid not adsorbed" ; rdfs:seeAlso "CVX:142" ; rdfs:subClassOf obo:VO_0000640, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1513 ] . obo:VO_0006077 obo:IAO_0000118 "tetanus toxoid unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "tetanus toxoid unspecified formulation" ; rdfs:seeAlso "CVX:112" ; rdfs:subClassOf obo:VO_0000640, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1513 ] . obo:VO_0006078 obo:IAO_0000118 "Tick-borne encephalitis vaccine (non-US)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tick-borne encephalitis vaccine (non-US)" ; rdfs:seeAlso "CVX:77" ; rdfs:subClassOf obo:VO_0000952, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11318 ] . obo:VO_0006079 obo:IAO_0000118 "Tick-borne encephalitis inactivated PF 0.25mL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tick-borne encephalitis vaccine inactivated preservative free 0.25mL dose" ; rdfs:seeAlso "CVX:223" ; rdfs:subClassOf obo:VO_0000952, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11318 ] . obo:VO_0006080 obo:IAO_0000118 "Tick-borne encephalitis inactivated PF 0.5mL" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tick-borne encephalitis vaccine inactivated preservative free 0.5mL dose" ; rdfs:seeAlso "CVX:224" ; rdfs:subClassOf obo:VO_0000952, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11318 ] . obo:VO_0006081 obo:IAO_0000118 "Tick-borne encephalitis unspecified" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tick-borne encephalitis vaccine unspecified" ; rdfs:seeAlso "CVX:222" ; rdfs:subClassOf obo:VO_0000952, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11318 ] . obo:VO_0006082 obo:IAO_0000118 "Typhoid conjugate vaccine (TCV)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Typhoid conjugate vaccine (non-US)" ; rdfs:seeAlso "CVX:190" ; rdfs:subClassOf obo:VO_0000671, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90370 ] . obo:VO_0006083 obo:IAO_0000118 "typhoid parenteral AKD (U.S. military)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "typhoid vaccine parenteral acetone-killed dried (U.S. military)" ; rdfs:seeAlso "CVX:53" ; rdfs:subClassOf obo:VO_0000671, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90370 ] . obo:VO_0006084 obo:IAO_0000118 "typhoid parenteral" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "typhoid vaccine parenteral other than acetone-killed dried" ; rdfs:seeAlso "CVX:41" ; rdfs:subClassOf obo:VO_0000671, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90370 ] . obo:VO_0006085 obo:IAO_0000118 "typhoid unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "typhoid vaccine unspecified formulation" ; rdfs:seeAlso "CVX:91" ; rdfs:subClassOf obo:VO_0000671, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_90370 ] . obo:VO_0006086 obo:IAO_0000118 "vaccinia (smallpox) diluted" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "vaccinia (smallpox) vaccine diluted" ; rdfs:seeAlso "CVX:105" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0006087 obo:IAO_0000118 "Vaccinia smallpox monkeypox vaccine live PF SQ or ID injection" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaccinia smallpox monkeypox vaccine live attenuated preservative free subcutaneous or intradermal injection" ; rdfs:seeAlso "CVX:206" ; rdfs:subClassOf obo:VO_0000651, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10255 ] . obo:VO_0006088 obo:IAO_0000118 "VEE unspecified formulation" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Venezuelan equine encephalitis vaccine unspecified formulation" ; rdfs:seeAlso "CVX:92" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0006089 obo:IAO_0000118 "VEE inactivated" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Venezuelan equine encephalitis inactivated" ; rdfs:seeAlso "CVX:81" ; rdfs:subClassOf obo:VO_0001499, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11036 ] . obo:VO_0006090 obo:IAO_0000118 "dengue fever" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "dengue fever vaccine" ; rdfs:seeAlso "CVX:56" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_12637 ] . obo:VO_0006091 obo:IAO_0000118 "Ebola unspecified" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola unspecified" ; rdfs:seeAlso "CVX:214" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_205488 ] . obo:VO_0006092 obo:IAO_0000115 "A combination vaccine adjuvant that is liposome-based adjuvant of a synthetic TLR agonist and saponin induced a Th1-biased immune response." ; obo:IAO_0000116 """Chemical Nature: Combination adjuvant Mechanism of Action: n/a Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Maria Lawrenz, Vaccine Formulation Institute""" ; obo:IAO_0000117 "Jie Zheng", "Maria Lawrenz", "Nilufer kosar", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "LMQ" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/?term=36119058", "https://www.ncbi.nlm.nih.gov/pubmed/?term=36634821", "https://www.ncbi.nlm.nih.gov/pubmed/?term=37029167" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/614" ; obo:VO_0005328 "78" ; a owl:Class ; rdfs:label "LMQ vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0006093 obo:IAO_0000115 "A vaccine adjuvant that is a peptide which is able to induce Th1/Th2/Th17 immune responses through the mechanism of selectively activates C5aR1 on mononuclear phagocytes vs neutrophils." ; obo:IAO_0000116 """Chemical Nature: Other - Peptide Mechanism of Action: (Primary) Selectively activates C5aR1 on mononuclear phagocytes vs neutrophils Immune profile induced: Th1/Th2/Th17 Route of immunization: IP, IV Point of Contact: Joseph Vetro, University of Nebraska Medical Center""" ; obo:IAO_0000117 "Jie Zheng", "Joseph Vetro", "Nilufer kosar", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "CPDI-02" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/?term=11710544", "https://www.ncbi.nlm.nih.gov/pubmed/?term=19836478", "https://www.ncbi.nlm.nih.gov/pubmed/?term=20965299" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/615" ; obo:VO_0005328 "40" ; a owl:Class ; rdfs:label "CPDI-02 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005376 ] . obo:VO_0006094 obo:IAO_0000115 "A vaccine adjuvant with a Toll-like receptor 9 (TLR9)-active oligonucleotide that is able to induce Th1/Th2 immune responses." ; obo:IAO_0000116 """Chemical Nature: Nucleic acid Mechanism of Action: TLR9 agonist Immune profile induced: Mixed Th1/Th2 Route of immunization: IM, SQ Point of Contact: Nikolai Petrovsky, Vaxine LTD """ ; obo:IAO_0000117 "Jie Zheng", "Nikolai Petrovsky", "Nilufer kosar", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "CpG55.2" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/?term=24554695", "https://www.ncbi.nlm.nih.gov/pubmed/?term=27387453", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32156809", "https://www.ncbi.nlm.nih.gov/pubmed/?term=32418798", "https://www.ncbi.nlm.nih.gov/pubmed/?term=33479242", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34399628", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34420786", "https://www.ncbi.nlm.nih.gov/pubmed/?term=34456075" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/616" ; obo:VO_0005328 "10" ; a owl:Class ; rdfs:label "CpG55.2 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0006095 obo:IAO_0000115 "A combination vaccine adjuvant that includes AS01-mimic, Immune Stimulating Complex (ISCOM) with a TLR4 agonist." ; obo:IAO_0000116 """Chemical Nature: Combination adjuvant Mechanism of Action: Cytokine induction in draining lymph nodes with increased lymph flow and lymph antigen accumulation Immune profile induced: Mixed Th1/Th2 Route of immunization: s.c. / i.m. / i.n. Point of Contact: Katarzyna Kaczmarek Michaels, Massachusetts Institute of Technology Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=34860581 https://www.ncbi.nlm.nih.gov/pubmed/?term=36131022 https://www.ncbi.nlm.nih.gov/pubmed/?term=34878851""" ; obo:IAO_0000117 "Jie Zheng", "Katarzyna Kaczmarek Michaels", "Nilufer kosar", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "SMNP" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/632" ; obo:VO_0005328 "77" ; a owl:Class ; rdfs:label "SMNP vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0006096 obo:IAO_0000115 "A combination vaccine adjuvant that is an AS01-mimic, liposomal adjuvant of a TLR4 agonist and saponin." ; obo:IAO_0000116 """Chemical Nature: - Natural compound - Synthetic derivative of natural compound - Combination adjuvant Mechanism of Action: MPLA: TLR4 agonist QS21: Sugar-lawn likely recog. by lectins to facilitate uptake by M_, DCs, etc Immune profile induced: Mixed Th1/Th2 Route of immunization: ID, IM Point of Contact: Mangala Rao, Walter Reed Army Institute of Research Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=34202178 https://www.ncbi.nlm.nih.gov/pubmed/?term=31827000 https://www.ncbi.nlm.nih.gov/pubmed/?term=34470866 https://www.ncbi.nlm.nih.gov/pubmed/?term=35632473 https://www.ncbi.nlm.nih.gov/pubmed/?term=36417525 https://www.ncbi.nlm.nih.gov/pubmed/?term=34914540 https://www.ncbi.nlm.nih.gov/pubmed/?term=32881968 https://www.ncbi.nlm.nih.gov/pubmed/?term=26372857 https://www.ncbi.nlm.nih.gov/pubmed/?term=36055874 https://www.ncbi.nlm.nih.gov/pubmed/?term=34202178 https://www.ncbi.nlm.nih.gov/pubmed/?term=36679887 https://www.ncbi.nlm.nih.gov/pubmed/?term=36934088 https://www.ncbi.nlm.nih.gov/pubmed/?term=34903722 https://www.ncbi.nlm.nih.gov/pubmed/?term=31775762 https://www.ncbi.nlm.nih.gov/pubmed/?term=28596090 https://www.ncbi.nlm.nih.gov/pubmed/?term=31151801 https://www.ncbi.nlm.nih.gov/pubmed/?term=34711815 https://www.ncbi.nlm.nih.gov/pubmed/?term=34159328 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT04268420 https://clinicaltrials.gov/ct2/show/NCT04296279 https://clinicaltrials.gov/ct2/show/NCT04784767 https://clinicaltrials.gov/ct2/show/NCT05500417 https://clinicaltrials.gov/ct2/show/NCT04826094 https://clinicaltrials.gov/ct2/show/NCT04658667 https://clinicaltrials.gov/ct2/show/NCT05423418""" ; obo:IAO_0000117 "Jie Zheng", "Mangala Rao", "Nilufer kosar", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "ALFQ" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/633" ; obo:VO_0005328 "79" ; a owl:Class ; rdfs:label "ALFQ vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0006097 obo:IAO_0000115 "A vaccine adjuvant which is a small molecule TLR agonist that drives a mixed Th1/Th2 response." ; obo:IAO_0000116 """Chemical Nature: Small molecule Mechanism of Action: Innate immune activation Immune profile induced: Mixed Th1/Th2 Route of immunization: IM Point of Contact: Dennis Carson, UCSD""" ; obo:IAO_0000117 "Dennis Carson", "Jie Zheng", "Nilufer kosar", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "2G023A" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/648" ; obo:VO_0005328 "81" ; a owl:Class ; rdfs:label "2G023A vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0006098 obo:IAO_0000115 "A vaccine adjuvant, a small molecule TLR agonist that drives a mixed Th1/Th2 response." ; obo:IAO_0000116 """Chemical Nature: Small molecule Mechanism of Action: Innate immune activation Immune profile induced: Mixed Th1/Th2 Route of immunization: IM Point of Contact: Dennis Carson, UCSD""" ; obo:IAO_0000117 "Dennis Carson", "Jie Zheng", "Nilufer kosar", "Oliver He", "Wolfgang Leitner" ; obo:IAO_0000118 "2G053" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/649" ; obo:VO_0005328 "80" ; a owl:Class ; rdfs:label "2G053 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0006099 obo:IAO_0000115 "A combination vaccine adjuvant of a synthetic TLR agonist and aluminum salt." ; obo:IAO_0000116 """Chemical Nature: - Synthetic derivative of natural compound - Combination adjuvant - Mineral salt Mechanism of Action: Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: SQ, IM Point of Contact: Valerie Soza, Access to Advanced Health Institute (AAHI) Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=37454145 https://www.ncbi.nlm.nih.gov/pubmed/?term=24556505 https://www.ncbi.nlm.nih.gov/pubmed/?term=28828575 https://www.ncbi.nlm.nih.gov/pubmed/?term=30013570 https://www.ncbi.nlm.nih.gov/pubmed/?term=24211167 https://www.ncbi.nlm.nih.gov/pubmed/?term=23933525 https://www.ncbi.nlm.nih.gov/pubmed/?term=34597297 https://www.ncbi.nlm.nih.gov/pubmed/?term=36996185 https://www.ncbi.nlm.nih.gov/pubmed/?term=28464026 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT03910972 https://clinicaltrials.gov/ct2/show/NCT02126462 https://clinicaltrials.gov/ct2/show/NCT02839161 https://clinicaltrials.gov/ct2/show/NCT03110757 https://clinicaltrials.gov/ct2/show/NCT02337855 https://clinicaltrials.gov/ct2/show/NCT01717950 https://clinicaltrials.gov/ct2/show/NCT02476773 https://clinicaltrials.gov/ct2/show/NCT01261130 https://clinicaltrials.gov/ct2/show/NCT01385189 https://clinicaltrials.gov/ct2/show/NCT03172975""" ; obo:IAO_0000117 "Jie Zheng", "Nilufer kosar", "Oliver He", "Valerie Soza", "Wolfgang Leitner" ; obo:IAO_0000118 "GLA-Alum" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/650" ; obo:VO_0005328 "83" ; a owl:Class ; rdfs:label "GLA-Alum vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0006100 obo:IAO_0000115 "A combination vaccine adjuvant of a synthetic TLR4 agonist and aluminum salt." ; obo:IAO_0000116 """Chemical Nature: - Synthetic derivative of natural compound - Combination adjuvant - Mineral salt Mechanism of Action: Innate Immune Activation Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Valerie Soza, Access to Advanced Health Institute (AAHI) Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=26901122 https://www.ncbi.nlm.nih.gov/pubmed/?term=32983577""" ; obo:IAO_0000117 "Jie Zheng", "Nilufer kosar", "Oliver He", "Valerie Soza", "Wolfgang Leitner" ; obo:IAO_0000118 "SLA-Alum" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/651" ; obo:VO_0005328 "82" ; a owl:Class ; rdfs:label "SLA-Alum vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001354, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0006101 obo:IAO_0000115 "An emulsion vaccine adjuvant that includes squalene-based oil-in-water emulsion." ; obo:IAO_0000116 """Chemical Nature: Emulsion Mechanism of Action: n/a Immune profile induced: Mixed Th1/Th2 Route of immunization: IM, SQ Point of Contact: Valerie Soza, Access to Advanced Health Institute (AAHI) Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=19679214 https://www.ncbi.nlm.nih.gov/pubmed/?term=22896687 https://www.ncbi.nlm.nih.gov/pubmed/?term=28429728 https://www.ncbi.nlm.nih.gov/pubmed/?term=37495191 https://www.ncbi.nlm.nih.gov/pubmed/?term=36256646 https://www.ncbi.nlm.nih.gov/pubmed/?term=28089141 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT03330899 https://clinicaltrials.gov/ct2/show/NCT01612000 https://clinicaltrials.gov/ct2/show/NCT02464163 https://clinicaltrials.gov/ct2/show/NCT02464163""" ; obo:IAO_0000117 "Jie Zheng", "Nilufer kosar", "Oliver He", "Valerie Soza", "Wolfgang Leitner" ; obo:IAO_0000118 "Stable Emulsion (SE)" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/652" ; obo:VO_0005328 "84" ; a owl:Class ; rdfs:label "Stable Emulsion (SE) vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005311 ] . obo:VO_0006102 obo:IAO_0000117 "Jie Zheng" ; a owl:Class ; rdfs:label "oligonucleotide vaccine adjuvant" ; rdfs:subClassOf obo:VO_0000580 . obo:VO_0006103 obo:IAO_0000115 "An emulsion vaccine adjuvant that is squalene-based adjuvant, induces T follicular helper cells and humoral immune responses via alpha-tocopherol component." ; obo:IAO_0000116 """Chemical Nature: Emulsion Mechanism of Action: n/a Immune profile induced: Th1-biased Route of immunization: IM Point of Contact: Maki Hayase, Shionogi &Co., Ltd Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=36372670 https://www.ncbi.nlm.nih.gov/pubmed/?term=36891311 https://www.ncbi.nlm.nih.gov/pubmed/?term=36460696 https://www.ncbi.nlm.nih.gov/pubmed/?term=35691872 Ongoing clinical trials: https://clinicaltrials.gov/ct2/show/NCT05212948""" ; obo:IAO_0000117 "Jie Zheng", "Maki Hayase", "Nilufer kosar" ; obo:IAO_0000118 "A-910823" ; obo:IAO_0000119 "PMID:36891311" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/666" ; obo:VO_0005328 "90" ; a owl:Class ; rdfs:label "A-910823 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0001355, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0006104 obo:IAO_0000115 "An oligonucleotide vaccine adjuvant that is a TLR9-agonistic adjuant containing a CpG oligonucleotide annealed to a complementary strand with an amphiphilic chain unit, acts as a potent cancer vaccine adjuvant by targeting draining lymph nodes." ; obo:IAO_0000116 """Chemical Nature: Oligonucleotide Mechanism of Action: Activation of TLR9 signaling pathway Immune profile induced: Th1-biased Route of immunization: IM, SQ Point of Contact: Maki Hayase, Shionogi &Co., Ltd Pubmed References: https://www.ncbi.nlm.nih.gov/pubmed/?term=35003132 https://www.ncbi.nlm.nih.gov/pubmed/?term=37243234 Ongoing clinical trials: N/A""" ; obo:IAO_0000117 "Jie Zheng", "Maki Hayase", "Nilufer kosar" ; obo:IAO_0000118 "S-540956" ; obo:IAO_0000119 "PMID:35003132", "PMID:37243234" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/667" ; obo:VO_0005328 "91" ; a owl:Class ; rdfs:label "S-540956 vaccine adjuvant" ; rdfs:subClassOf obo:VO_0006102, [ a owl:Restriction ; owl:onProperty obo:VO_0005312 ; owl:someValuesFrom obo:VO_0005309 ] . obo:VO_0007000 obo:IAO_0000115 "A recombinant oncolytic adenovirus encoding the immunohematopoietic cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with potential antineoplastic activity. Upon administration, the oncolytic adenovirus selectively infects and replicates in tumor cells, which may result in tumor cells lysis. Synergistically, GM-CSF (sargramostim) expressed by the oncolytic adenovirus may promote a cytotoxic T cell response against tumor cells harboring the oncolytic adenovirus, resulting in an immune-mediated tumor cell death." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C48412", "NCT: https://clinicaltrials.gov/ct2/show/NCT00109655", "PubMed:28530155", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5475" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/75" ; obo:OGG_0000000006 "1437" ; obo:VO_0001818 "5475" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CSF-2" ; rdfs:label "Oncolytic Adenovirus Encoding GM-CSF Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007001 obo:IAO_0000115 "A non-replicating recombinant adenovirus type 5 (Ad5)-vector encoding the gene for interferon alpha-2b (IFN_2b) and the gene transfer enhancement agent Syn 3, with potential antineoplastic activity. Upon intravesical administration, recombinant adenovirus-interferon with Syn3 transfects both cancerous and normal bladder cells, and the adenovirus secretes interferon (IFN_2b) into the bladder. IFN exerts a direct antitumor killing effect and a bystander effect, thereby killing adjacent, non-transfected cancerous bladder cells. Syn 3 enhances the ability of the adenoviral vector to transfect cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C104743", "NCT: https://clinicaltrials.gov/ct2/show/NCT02773849", "PubMed:28834453", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5047" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/322" ; obo:OGG_0000000006 "3440" ; obo:VO_0001818 "5047" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IFNA2" ; rdfs:label "Recombinant Adenovirus-Interferon/Syn3 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007002 obo:IAO_0000115 "A cancer vaccine adjuvant consisting of a recombinant fowlpox virus encoding human granulocyte-macrophage colony-stimulating factor (GM-CSF). GM-CSF binds to specific cell surface receptors on various immuno-hematopoietic cell types, enhancing their proliferation and differentiation and stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Administration of recombinant fowlpox GM-CSF vaccine adjuvant may induce an immune response against tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2686", "NCT: https://clinicaltrials.gov/ct2/show/NCT00072137", "PubMed:15780740", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4994" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/328" ; obo:OGG_0000000006 "1437" ; obo:VO_0001818 "4994" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM-CSF" ; rdfs:label "Recombinant Fowlpox GM-CSF Vaccine Adjuvant" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007003 obo:IAO_0000115 "A peptide vaccine derived from cytomegalovirus (CMV) antigens with potential immunostimulating activity. Intradermal administration of the PEP-CMV vaccine may stimulate the immune system to mount a specific helper and cytotoxic T-lymphocyte (CTL) response against CMV-infected tumor cells. Infection with the herpesvirus CMV may play a significant role in tumor cell initiation and progression as well as chemoresistance." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C107243", "NCT: https://clinicaltrials.gov/ct2/show/NCT02864368", "PubMed:31806885", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5259" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/118" ; obo:OGG_0000000006 "18826" ; obo:VO_0001818 "5259" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: pp65(Lcp 1)" ; rdfs:label "PEP-CMV Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007004 obo:IAO_0000115 "A cancer vaccine consisting of a human epidermal growth factor receptor variant III (EGFRvIIi)-specific peptide conjugated to the non-specific immunomodulator keyhole limpet hemocyanin (KLH) with potential antineoplastic activity. Vaccination with rindopepimut may elicit a cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing EGFRvIII. EGFRvIII, a functional variant of EGFR that is not expressed in normal tissues, was originally discovered in glioblastoma multiforme (GBM) and has also been found in various other cancers such as breast, ovarian, metastatic prostate, colorectal, and head and neck cancers. EGFRvIII contains an 83 amino acid deletion in its extracellular domain and has been shown to transform NIH/3T3 mouse embryonic fibroblast cells in vitro." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C69076", "NCT: https://clinicaltrials.gov/ct2/show/NCT01498328", "PubMed:28844499", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5032" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/120" ; obo:OGG_0000000006 "1956" ; obo:VO_0001818 "5032" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: EGFR" ; rdfs:label "PF-04948568 Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007005 obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29786", "PubMed:21078216", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5192" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/324" ; obo:OGG_0000000006 "945006" ; obo:VO_0001818 "5192" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: lacZ" ; rdfs:label "Recombinant Adenovirus-LacZ Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007006 obo:IAO_0000115 "A personalized peptide-based cancer vaccine comprised of one or two de novo synthesized patient-specific tumor-mutated peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB mutated tumor-specific peptides vaccine therapy APVAC2 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the selected mutated tumor-associated peptides, which results in decreased GB growth. These peptides are specifically selected and synthesized based on the expression of the patient√ïs own mutated tumor-associated antigens, which were detected during individual tumor genome sequencing." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C116332", "NCT: https://clinicaltrials.gov/ct2/show/NCT02149225", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5086" ; obo:VO_0001818 "5086" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Synthetic Glioblastoma Mutated Tumor-specific Peptides Vaccine Therapy APVAC2" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007007 obo:IAO_0000115 "A personalized peptide-based cancer vaccine comprised of five to ten peptides associated with glioblastoma (GB), with potential immunomodulating and antineoplastic activities. Vaccination with synthetic GB tumor-associated peptides vaccine therapy APVAC1 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the tumor associated peptides, and results in decreased GB growth. The peptides are derived from a glioma actively-personalized vaccine consortium (GAPVAC) warehouse and are specifically selected based on the patient's expression of tumor-associated antigens." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C116331", "NCT: https://clinicaltrials.gov/ct2/show/NCT02149225", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5231" ; obo:OGG_0000000006 "1956" ; obo:VO_0001818 "5231" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: EGFR" ; rdfs:label "Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007008 obo:IAO_0000115 "An orally available DNA cancer vaccine containing an attenuated strain of the bacterium Salmonella typhimurium encoding murine vascular endothelial growth factor receptor 2 (VEGFR-2) (VXM01), with potential immunomodulating, anti-angiogenic and antineoplastic activity. Upon oral administration and successful transduction, VEGFR-2 DNA vaccine VXM01 expresses VEGFR-2 in addition to inducing the expression of T-cell activation markers, such as CD25, interleukin-2, the early T-cell activation antigen CD69 and the lymphocyte function-associated antigen LFA-2. The immune response targets the fast growing VEGFR-2 expressing endothelial cells found in the tumor vasculature, thereby blocking angiogenesis which may ultimately inhibit tumor cell proliferation. VEGFR-2 is a receptor tyrosine kinase overexpressed on proliferating endothelial cells in the tumor vasculature." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C99378", "NCT: https://clinicaltrials.gov/ct2/show/NCT02718443", "PubMed:29632710", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5521" ; obo:OGG_0000000006 "3791" ; obo:VO_0001818 "5521" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KDR" ; rdfs:label "VEGFR-2 DNA Vaccine VXM01" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007009 obo:IAO_0000115 "A cancer peptide vaccine comprised of a human leukocyte antigen (HLA) A2/A3 restricted HER2/neu (ERBB2) peptide from the extracellular domain of the HER2 protein (E75 peptide) and combined with the immunoadjuvant granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunomodulating and antineoplastic activity. Upon intradermal injection, nelipepimut-S plus GM-CSF vaccine may induce a specific cytotoxic T-lymphocyte (CTL) response against HER2/neu-expressing tumor cell types. HER2/neu, a tumor-associated antigen and a member of the epidermal growth factor receptor family of tyrosine kinases, is overexpressed in various tumor cell types. GM-CSF potentiates the antitumor immune response." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C99228", "NCT: https://clinicaltrials.gov/ct2/show/NCT02636582", "PubMed:33485895", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5363" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/54" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5363" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Nelipepimut-S Plus GM-CSF Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007010 obo:IAO_0000115 "A cancer vaccine consisting of one or more long, synthetic peptides derived from patient-specific breast cancer tumor-associated antigens (TAAs), with potential immunomodulating and antineoplastic activities. Upon intramuscular administration of the personalized synthetic long peptide breast cancer vaccine, the peptides stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the TAAs, which results in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C121947", "NCT: https://clinicaltrials.gov/ct2/show/NCT02427581", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5348" ; obo:VO_0001818 "5348" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Personalized Synthetic Long Peptide Breast Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007011 obo:IAO_0000115 "A plasmid DNA cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu proto-oncogene. Upon administration and after cellular uptake by skin or muscle cells, the pNGVL3-hICD vaccine plasmid expresses the HER-2/neu protein, which, after intracellular processing, may elicit both antigen-specific cytotoxic T-lymphocyte (CTL) and humoral immune responses against tumor cells expressing HER-2. The HER-2/neu ICD protein is highly immunogenic and, as a subdominant epitope, may be associated with decreased immune tolerance." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61146", "NCT: https://clinicaltrials.gov/ct2/show/NCT05163223", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5040" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/122" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5040" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "pNGVL3-hICD Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007012 obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29785", "PubMed:11590241", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5530" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/320" ; obo:VO_0001818 "5530" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Recombinant Adenovirus-Cre Recombinase Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007013 obo:IAO_0000115 "An√äimmunotherapeutic√äcomposed of the Wilms tumor 1 (WT1) and an as of yet undisclosed adjuvant, with potential antineoplastic activity. Upon administration, the immune system may be stimulated to exert a cytotoxic T-lymphocyte (CTL) response against√äWT1-expressing tumor cells. The adjuvant stimulates the immune system's response to√äWT1.√äWT1, a tumor-associated antigen (TAA) and transcription factor, is overexpressed in a variety of tumor cell types." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C116880", "NCT: https://clinicaltrials.gov/ct2/show/NCT01220128", "PubMed:30562862", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5297" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/326" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5297" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "Recombinant Anti-WT1 Immunotherapeutic GSK2302024A Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007014 obo:IAO_0000115 "A cancer vaccine consisting of a truncated recombinant HER2 peptide (dHER2) with potential antineoplastic activity. Upon administration, recombinant dHER2 vaccine may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against tumor cells that overexpress the HER2 protein, resulting in tumor cell lysis. The HER2 protein is a tumor-associated antigen (TAA) that is overexpressed in a variety of cancers. dHER2 includes the extracellular domain (ECD) and a part of the intracellular domain (ICD) of the HER2 protein." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C49177", "NCT: https://clinicaltrials.gov/ct2/show/NCT00140738", "PubMed:26975189", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5241" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5241" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Recombinant dHER2 Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007015 obo:IAO_0000115 "A cancer vaccine containing autologous dendritic cells pulsed with a fusion product of an epitope of human tumor-associated epithelial mucin 1 (MUC1) antigen and the vaccine adjuvant mannan (oxidized mannose), with potential antineoplastic activity. When the modified dendritic cells are returned to the patient, they may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the MUC1 antigen, resulting in tumor cell lysis. Addition of manna in this vaccine, enhances immune recognition. MUC1 antigen, a high-molecular-weight transmembrane glycoprotein, is overexpressed on many tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C102782", "NCT: https://clinicaltrials.gov/ct2/show/NCT00004156", "PubMed:9656453", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5077" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5077" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "Recombinant Human MUC1-Oxidized Polymannose-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007016 obo:IAO_0000115 "A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the 5T4 fetal oncoprotein (MVA-h5T4). Vaccination with recombinant modified vaccinia Ankara-5T4 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing 5T4 fetal oncoprotein antigen, resulting in tumor cell lysis. The MVA viral vector, derived from the replication-competent strain Ankara, is a highly attentuated, replication-defective vaccinia strain incapable of virion assembly." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C49087", "NCT: https://clinicaltrials.gov/ct2/show/NCT00227474", "PubMed:18990081", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5058" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/337" ; obo:OGG_0000000006 "7162" ; obo:VO_0001818 "5058" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TPBG" ; rdfs:label "Recombinant Modified Vaccinia Ankara-5T4 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007017 obo:IAO_0000115 "A vaccinia virus based vaccine expressing human tumor associated epithelial mucin (DF3 antigen; MUC1). MUC1 antigen, a membrane bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in various tumors such as breast, prostate, and ovarian cancers. This vaccine could be used in development of immunotherapeutics against cancers expressing MUC1." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2510", "NCT: https://clinicaltrials.gov/ct2/show/NCT00071942", "PubMed:9101412", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5281" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/338" ; obo:OGG_0000000006 "354", "4582" ; obo:VO_0001818 "5281" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1|Gene name: KLK3" ; rdfs:label "Recombinant Vaccinia DF3/MUC1 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007018 obo:IAO_0000115 "A vaccine containing a recombinant vaccinia virus that encodes the gene for human mucin-1, a tumor-associated antigen. Upon administration, recombinant vaccinia-MUC-1 vaccine may elicit a MUC-1-specific cytotoxic T cell response against tumor cells bearing MUC-1." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2732", "NCT: https://clinicaltrials.gov/ct2/show/NCT00071942", "PubMed:12898638", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5321" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/347" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5321" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "Recombinant Vaccinia-MUC-1 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007019 obo:IAO_0000115 "A vaccine containing a pancarcinoma carbohydrate antigen conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Sialylated Tn antigen (sTn) is a monosaccharide glycan usually O-linked to serine or threonine residues of mucins found on most epithelial cancers. Conjugation with KLH, a hapten carrier and an immunostimulant, improves host immune responses. Vaccination with sTn-KLH vaccine may produce antibodies and elicit a cytotoxic T lymphocyte (CTL) response against those tumor cells expressing sTn, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1690", "NCT: https://clinicaltrials.gov/ct2/show/NCT00003638", "PubMed:23983823", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5425" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/361" ; obo:VO_0001818 "5425" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: sialyl-Tn" ; rdfs:label "Sialyl Tn-KLH Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007020 obo:IAO_0000115 "A vaccine comprised of a synthetic Sialyl-Tn antigen linked to the protein carrier, keyhole limpet hemocyanin (KLH), administered with immunostimulant, Detox. Vaccination with STn-KLH plus Detox may elicit an IgG-based anti-STn antibody response and ultimately a cytotoxic T-cell response against STn-expressing cancer cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2501", "NCT: https://clinicaltrials.gov/ct2/show/NCT00003638", "PubMed:7690215", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5061" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/363" ; obo:VO_0001818 "5061" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: sialyl-Tn" ; rdfs:label "STn-KLH plus Detox Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007021 obo:IAO_0000115 "A cancer vaccine comprised of multiple synthetic breast cancer peptides and the adjuvant tetanus toxoid helper peptide emulsified in the adjuvant Montanide ISA-51 with immunopotentiation activity. Vaccination with this cancer vaccine may elicit a specific cytotoxic T-lymphocyte response against breast cancer cells. Synthetic breast cancer peptides may stimulate the immune response against cells that produce breast cancer markers such as erbB2 (HER2/neu) while tetanus toxoid helper peptide binds to class II MHC molecules as a nonspecific vaccine helper epitope, resulting in a long-term immunopotentiation by increasing the helper T-cell response. Montanide ISA-51, also known as incomplete Freund's adjuvant or IFA, is a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant that non-specifically stimulates cell-mediated immune responses to antigens." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61076", "NCT: https://clinicaltrials.gov/ct2/show/NCT00304096", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5271" ; obo:OGG_0000000006 "6007" ; obo:VO_0001818 "5271" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: RHD" ; rdfs:label "Synthetic Breast Cancer Peptides-Tetanus Toxoid-Montanide ISA-51 Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007022 obo:IAO_0000115 "A vaccine containing a clustered pancarcinoma carbohydrate antigen conjugated with keyhole limpet hemocyanin (KLH) with potential antineoplastic activity. Alpha-N-acetylgalactosamine (Tn) is a monosaccharide usually O-linked to serine or threonine residues of mucins found on most epithelial cancers with the highest expression on prostate cancer. This vaccine contains the Tn epitope cluster (c) that is synthesized by linking 3 copies of the Tn epitope on a threonine backbone to achieve the essential immunogenic structure. KLH is a hapten carrier and serves as an immunostimulant to improve immune recognition. Vaccination with Tn(c)-KLH vaccine may produce antibodies and elicit a cytotoxic T lymphocyte (CTL) response against those tumor cells expressing Tn antigen, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2474", "NCT: https://clinicaltrials.gov/ct2/show/NCT00030823", "PubMed:9579798", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5025" ; obo:VO_0001818 "5025" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Tn(c)-KLH Conjugate Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007023 obo:IAO_0000115 "A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma. (NCIT_C85466)." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C85466", "NCT: https://clinicaltrials.gov/ct2/show/NCT00900809", "PubMed:18425107", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5026" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/50" ; obo:OGG_0000000006 "107653060" ; obo:VO_0001818 "5026" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IL12" ; rdfs:label "Natural Killer Cells ZRx101 vaccine" ; rdfs:subClassOf obo:VO_0005427, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007024 obo:IAO_0000115 "A cancer vaccine consisting of an immunogenic peptide derived from the cancer-testis antigen (NY-ESO-1), an antigen found in normal testis and various tumors. Vaccination with NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response to cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2657", "NCT: https://clinicaltrials.gov/ct2/show/NCT05479045", "PubMed:24397899", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5206" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/55" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5206" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B" ; rdfs:label "NY-ESO-1 peptide vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005489, obo:VO_0005493, obo:VO_0005496, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5041 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007025 obo:IAO_0000115 "A√äplasmid√äDNA√äencoding an immunogenic peptide derived from the√äcancer-testis antigen√äNY-ESO-1√äwith potential immunostimulating and antitumor activities. Upon administration,√äNY-ESO-1√äplasmid√äDNA√äcancer√ävaccine√ämay stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the√äNY-ESO-1√äantigen, resulting in tumor cell lysis.√äNY-ESO-1√äis a tumor associated antigen (TAA) found in normal testes and expressed on the surfaces of various tumor cells, including melanoma, breast, bladder, prostate, lung, ovarian, and hepatocellular tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C62452", "NCT: https://clinicaltrials.gov/ct2/show/NCT00199849", "PubMed:15102697", "PubMed:21900253", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5283" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/56", "https://github.com/vaccineontology/VO/issues/58" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5283" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B" ; rdfs:label "NY-ESO-1 plasmid DNA cancer vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0003140, obo:VO_0005425, obo:VO_0005485, obo:VO_0005495, obo:VO_0005496, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3908 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5041 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007026 obo:IAO_0000115 "A cancer vaccine composed of a recombinant form of the tumor antigen NY-ESO-1 and glucopyranosyl lipid adjuvant (GLA)-stable emulsion (GLA-SE), with potential antineoplastic and immunomodulating activities. Upon intramuscular injection, the adjuvant portion of the NY-ESO-1/GLA-SE vaccine ID-G30 binds to toll-like receptor subtype 4 (TLR-4) expressed on dendritic cells (DCs), monocytes, macrophages and B cells. The activated DCs present the NY-ESO-1 antigen to Th1 CD4 T-lymphocytes. This leads to the induction of cytotoxic T lymphocytes (CTLs) and the killing of NY-ESO-1-expressing tumor cells. This vaccine also induces specific antibody responses and increases the production of inflammatory cytokines." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C113432", "NCT: https://clinicaltrials.gov/ct2/show/NCT02015416", "PubMed:31069460", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5445" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/85" ; obo:OGG_0000000006 "1485", "7099" ; obo:VO_0001818 "5445" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B|Gene name: TLR4" ; rdfs:label "NY-ESO-1/GLA-SE vaccine ID-G305AmN" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, obo:VO_0005484, obo:VO_0005486, obo:VO_0005493, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5409 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007027 obo:IAO_0000115 "A recombinant nonapeptide used as an antineoplastic vaccine. NY-ESO-1b peptide vaccine contains the amino acid sequence SLLMWITQC, derived from the cancer-testis tumor antigen (NY-ESO-1), which is expressed on tumor cells of many different types, including melanomas. Vaccination with this peptide vaccine may elicit strong humoral and cellular immune responses to NY-ESO-1-expressing cancers." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C68999", "NCT: https://clinicaltrials.gov/ct2/show/NCT00199836", "PubMed:15501973", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5428" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/112" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5428" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B" ; rdfs:label "NY-ESO-1b peptide vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007028 obo:IAO_0000115 "A tumor-associated antigen belonging to the family of immunogenic testicular proteins that are aberrantly expressed in human cancers in a lineage-nonspecific fashion. Reverse transcription-PCR analysis showed NY-ESO-1 mRNA expression in a variable proportion of a wide array of human cancers, including melanoma, breast cancer, bladder cancer, prostate cancer, and hepatocellular carcinoma; and restricted expression in normal tissues, with high-level mRNA expression found only in testis and ovary tissues. The gene for NY-ESO-1 maps to Xq28 and codes for an 18-kDa protein having no homology with any known protein. NY-ESO-1 elicits a strong, integrated humoral and cellular immune response in a high proportion of patients with NY-ESO-1-expressing tumors and is under investigation as a cancer immunotherapy agent." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26680", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5182" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/76" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5182" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B" ; rdfs:label "NY-ESO-B Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005425, obo:VO_0005429, obo:VO_0005484, obo:VO_0005485, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007029 obo:IAO_0000115 "An E1B-55kDa-deleted adenovirus that is able to selectively replicate in and lyse TP53-deficient human tumor cells. After tumor cell lysis, released viruses infect neighboring tumor cells, tripping a chain of ONYX-015-mediated tumor cell cytotoxicity." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2830", "NCT: https://clinicaltrials.gov/ct2/show/NCT00006106", "PubMed:11892945", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5486" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/73" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "5486" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53" ; rdfs:label "ONYX-015 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005497, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11934 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_8557 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:MONDO_0023644 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007030 obo:IAO_0000115 "A peptide-based cancer vaccine composed of amino acids 264 to 272 of the wild-type protein encoded by the P53 gene. p53 peptide vaccine may elicit an HLA-A2.1-restricted cytotoxic T lymphocyte immune response against tumor cells that overexpress p53 protein." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1986", "NCT: https://clinicaltrials.gov/ct2/show/NCT00001827", "PubMed:24583792", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5255" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "5255" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53" ; rdfs:label "p53 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007031 obo:IAO_0000115 "A peptide-based vaccine containing a pan HLA DR-binding epitope (PADRE) fused to a cytomegalovirus (CMV) peptide epitope, with potential anti-viral and immunomodulating activities. Upon administration, PADRE-CMV fusion peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against CMV in the CMV-infected host. The synthetic peptide PADRE is a universal helper T cell epitope." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C78820", "NCT: https://clinicaltrials.gov/ct2/show/NCT00722839", "PubMed:22402037", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5441" ; obo:VO_0001818 "5441" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "PADRE-CMV Fusion Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007032 obo:IAO_0000115 "A synthetic HIV-1 envelope peptide that was developed for use as a vaccine. Vaccination with PCLUS 3-18MN may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) and T helper cell responses, and induce the production of neutralizing antibodies." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2786", "NCT: https://clinicaltrials.gov/ct2/show/NCT00001386", "PubMed:10546852", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5451" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/115" ; obo:VO_0001818 "5451" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "PCLUS 3-18MN Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007033 obo:IAO_0000115 "A synthetic HIV-1 envelope peptide that was developed for use as a vaccine. Vaccination with PCLUS 6.1-18MN may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) and T helper cell responses, and induce the production of neutralizing antibodies." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2787", "NCT: https://clinicaltrials.gov/ct2/show/NCT00001386", "PubMed:10546852", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5443" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/116" ; obo:VO_0001818 "5443" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "PCLUS 6.1-18MN Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007034 obo:IAO_0000115 "A cancer vaccine consisting of Her2/neu peptides incorporated into microspheres of poly (lactide-co-glycolide) (PLGA), a biodegradable polymer. Poly microsphere encapsulated HER2/neu oral vaccine has been investigated for use in immunotherapy for tumors positive for HER-2/neu, a tumor associated antigen that is overexpressed in various cancers, including breast and ovarian cancer.√ä" ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2718", "NCT: https://clinicaltrials.gov/ct2/show/NCT02795988", "PubMed:29448628", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5176" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5176" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Poly Microsphere Encapsulated HER2/neu Oral Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007035 obo:IAO_0000115 "A cancer vaccine containing a RAS oncogene-encoded peptide with potential antineoplastic activity. RAS peptide cancer vaccine may stimulate a RAS peptide-specific antitumoral T-cell cytotoxic immune response, resulting in an inhibition of tumor cell proliferation and tumor cell death." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2438", "NCT: https://clinicaltrials.gov/ct2/show/NCT00019006", "PubMed:33016924", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5320" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/189" ; obo:OGG_0000000006 "3845" ; obo:VO_0001818 "5320" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KRAS" ; rdfs:label "RAS Peptide Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005430, obo:VO_0005486, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007036 obo:IAO_0000115 "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the stimulatory molecule transgene B7-1. Recombinant fowlpox-B7.1 (rF-B7.1) vaccine may enhance antigen presentation and activate antitumoral cytotoxic T-cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2666", "NCT: https://clinicaltrials.gov/ct2/show/NCT00030693", "PubMed:12969559", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5424" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/329" ; obo:OGG_0000000006 "941" ; obo:VO_0001818 "5424" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD80" ; rdfs:label "Recombinant Fowlpox-B7.1 Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007037 obo:IAO_0000115 "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). This agent may enhance CEA presentation to antigen presenting cells (APC) and activate cytotoxic T-cells against CEA-expressing tumors." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2620", "NCT: https://clinicaltrials.gov/ct2/show/NCT00028496", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5049" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/330" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5049" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5" ; rdfs:label "Recombinant Fowlpox-CEA(6D)/TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007038 obo:IAO_0000115 "A whole, heat-killed, recombinant Saccharomyces cerevisiae yeast-based vaccine genetically altered to express the carcinoembryonic antigen (CEA) peptide 610D with potential immunostimulating and antineoplastic activities. Upon administration, recombinant Saccharomyces cerevisia-CEA(610D) vaccine GI-6207 may stimulate a host cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells, which may result in tumor cell lysis. CEA, a tumor associated antigen, is overexpressed on a wide variety of human cancer cells including colorectal, gastric, lung, breast and pancreatic cancer cells. CEA 610D encodes for 9 amino acids (605-613) in which aspartate is substituted for asparagine at position 610 (610D) in order to strengthen the induction of the CTL response against CEA-expressing tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C82371", "NCT: https://clinicaltrials.gov/ct2/show/NCT00924092", "PubMed:22862954", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5152" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5152" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "Recombinant Saccharomyces Cerevisia-CEA(610D)-Expressing Vaccine GI-6207" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007039 obo:IAO_0000115 "A vaccine consisting of recombinant vaccinia virus encoding the tumor-associated antigen carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1, and LFA-3; also called TRICOM). Vaccination with recombinant vaccinia-CEA(6D)-TRICOM vaccine stimulates the host immune system to mount a T-cell response against tumor cells expressing the CEA antigen. The use of TRICOM in the vaccine may elicit a greater antitumor cytotoxic T lymphocyte (CTL) immune response compared to the use of vaccinia-CEA alone." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2619", "NCT: https://clinicaltrials.gov/ct2/show/NCT00217373", "PubMed:27581603", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5037" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/342" ; obo:OGG_0000000006 "111518" ; obo:VO_0001818 "5037" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Cea-Mouse" ; rdfs:label "Recombinant Vaccinia-CEA(6D)-TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007040 obo:IAO_0000115 "An admixture of√ärecombinant√ävaccinia√ävirus encoding MUC-1 and√ärecombinant√ävaccinia√ävirus encoding the murine T-cell co-stimulatory molecule√äB7.1. MUC-1 is a glycosylated mucin that is overexpressed in breast, lung, pancreatic, prostate, stomach, colon, and ovarian carcinomas. Vaccination with MUC-1 in combination with√äB7.1 may enhance the cytotoxic T cell (CTL) immune response to tumors expressing MUC-1, compared to vaccination with MUC-1 alone." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29409", "PubMed:9101412", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5326" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/348" ; obo:OGG_0000000006 "12519", "4582" ; obo:VO_0001818 "5326" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1|Gene name: Cd80" ; rdfs:label "Recombinant Vaccinia-MUC1-B7 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005430, obo:VO_0005484, obo:VO_0005486, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007041 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant vaccinia viral vector encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1, an antigen found in normal testis and various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with recombinant vaccinia- NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48419", "NCT: https://clinicaltrials.gov/ct2/show/NCT00112957", "PubMed:29773080", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5389" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/349" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5389" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B" ; rdfs:label "Recombinant Vaccinia-NY-ESO-1 Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007042 obo:IAO_0000115 "A replication-incompetent, pathotropic, tumor matrix (collagen)-targeted, retroviral vector encoding an N-terminal deletion mutant form of the cyclin G1 gene with potential antineoplastic activity. Under the control of a hybrid long-terminal repeat/cytomegalovirus (CMV) promoter, retrovector encoding mutant anti-cyclin G expresses the mutant cyclin G1 construct, resulting in disruption of tumor cell cyclin G1 activity and decreased cellular proliferation and angiogenesis. This agent preferentially targets collagen of the tumor matrix because of the incorporation of the collagen-binding domain of von Willebrand factor (vWF) on the retrovector surface. Exploiting the collagen-targeting mechanism of vWF permits delivery of the retrovector to tumor sites where angiogenesis and collagen matrix exposure occur." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C49082", "NCT: https://clinicaltrials.gov/ct2/show/NCT00505271", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5437" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/355" ; obo:OGG_0000000006 "900" ; obo:VO_0001818 "5437" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CCNG1" ; rdfs:label "Retrovector Encoding Mutant Anti-Cyclin G1 Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005430, obo:VO_0005484, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007043 obo:IAO_0000115 "An autologous dendritic cell (DC) vaccine loaded with tumor-associated antigens (TAAs) derived from survivin, p53 and human epidermal growth factor receptor 2 (HER2 or ERBB2), with immunostimulating and antineoplastic activities. Upon administration, this DC vaccine may elicit a potent cytotoxic T-cell (CTL) response against tumor cells expressing these TAAs, resulting in tumor cell death. Survivin, p53 and HER2 are essential in neoplastic growth, and are considered to be universal tumor antigens." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C114285", "NCT: https://clinicaltrials.gov/ct2/show/NCT00978913", "PubMed:16096014", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5180" ; obo:OGG_0000000006 "2064", "373110", "7157" ; obo:VO_0001818 "5180" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Survivin|Gene name: ERBB2|Gene name: p53" ; rdfs:label "Survivin/p53/HER2 Antigen-loaded Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007044 obo:IAO_0000115 "A peptide vaccine containing a 15-mer peptide (DLAQMFFCFKELEGW), with C to M alteration at amino acid position 57, derived from the anti-apoptosis protein survivin, and conjugated with keyhole limpet hemocyanin (KLH), with potential immunopotentiating and antineoplastic activities. Upon subcutaneous administration of SVN53-67/M57-KLH peptide vaccine, this peptide is able to bind both HMC class I and II molecules and may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) as well as a T-helper cell response against survivin-expressing cancer cells. This may result in decreased tumor cell proliferation and ultimately tumor cell death. Survivin, a member of the inhibitor of apoptosis (IAP) family, expressed during embryonic development while absent in most normal adult cells, is upregulated in a variety of human cancers; its expression in tumors is associated with a more aggressive phenotype, decreased survival, and increased resistance to chemotherapy. KLH may enhance immune recognition and may promote an enhanced response. As SVN53-67 is weakly immunogenic in humans, the M57 alteration may lead to greater affinity towards HLA-A*0201 and thus an enhanced antitumor immune response." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C95705", "NCT: https://clinicaltrials.gov/ct2/show/NCT02334865", "PubMed:27576783", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5008" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/405" ; obo:OGG_0000000006 "373110" ; obo:VO_0001818 "5008" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Survivin" ; rdfs:label "SVN53-67/M57-KLH Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007045 obo:IAO_0000115 "A DNA vaccine consisting of a plasmid encoding the full-length sequence of the tumor-associated antigen (TAA) human telomerase reverse transcriptase (hTERT), which is the catalytic subunit of human telomerase and synthesizes telomeric DNA at the chromosome ends, containing two immunogenic mutations, with potential immunostimulating and antineoplastic activities. Upon intradermal vaccination of the hTERT-encoding DNA vaccine INO-1400 in combination with electroporation, hTERT protein is expressed and activates the immune system to mount a cytotoxic T-cell (CTL) response against telomerase-expressing tumor cells, which may result in tumor cell death. Telomerase prolongs the functional lifespan of cells via the restoration and maintenance of telomere length. Abnormally activated in tumorigenesis, telomerase is expressed in the majority of human cancer cells, but its expression is low or non-existent in normal cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C120118", "NCT: https://clinicaltrials.gov/ct2/show/NCT02960594", "PubMed:34230114", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5171" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/409" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5171" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "Synthetic hTERT DNA Vaccine INO-1400" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007046 obo:IAO_0000115 "A cancer vaccine consisting of E-PRA and E-PSM, two synthetic peptide analogs of PRAME (PReferential Antigen MElanoma) and PSMA (Prostate Specific Membrane Antigen), with potential immunostimulating activity. Upon direct administration into lymph nodes, synthetic peptides E-PRA and E-PSM vaccine may sitmulate a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing tumor cells. PRAME and PSMA are tumor-associated antigens upregulated and expressed on the cell surfaces of certain tumor cell types." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C67098", "NCT: https://clinicaltrials.gov/ct2/show/NCT00423254", "PubMed:21760528", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5496" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/412" ; obo:OGG_0000000006 "6277" ; obo:VO_0001818 "5496" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: S100A6" ; rdfs:label "Synthetic Peptides E-PRA And E-PSM Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007047 obo:IAO_0000115 "A peptide-based cancer vaccine, containing amino acid residues 27 through 35 of T cell receptor gamma alternate reading frame protein (TARP), with potential immunostimulatory and antineoplastic activities. Upon administration, TARP 27-35 peptide vaccine may stimulate a host cytotoxic T-cell (CTL) response against TARP-expressing tumor cells, resulting in tumor cell cytotoxicity. The nuclear protein TARP is commonly expressed on prostate and breast cancer cells and is highly immunogenic." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C85462", "NCT: https://clinicaltrials.gov/ct2/show/NCT00972309", "PubMed:27622067", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5448" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/413" ; obo:OGG_0000000006 "445347" ; obo:VO_0001818 "5448" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TARP" ; rdfs:label "TARP 27-35 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007048 obo:IAO_0000115 "A peptide-based cancer vaccine, consisting of amino acid residues 29 through 37 of T cell receptor gamma alternate reading frame protein (TARP) with a leucine-to-valine substitution at position 9, with potential immunostimulatory and antineoplastic activities. Upon administration, TARP 29-37-9V peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against TARP-expressing tumor cells, which may result in decreased tumor cell proliferation. The leucine-to-valine substitution at position 9 of this peptide improves its immunogenicity. The nuclear protein TARP is commonly expressed on prostate and breast cancer cells and is highly immunogenic." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C85463", "NCT: https://clinicaltrials.gov/ct2/show/NCT02362464", "PubMed:27622067", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5242" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/414" ; obo:OGG_0000000006 "445347" ; obo:VO_0001818 "5242" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TARP" ; rdfs:label "TARP 29-37-9V Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007049 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant vector encoding the tumor-associated carcinoembryonic antigen (CEA) that is√äcontaminated√äwith bovine viral diarrhea virus (BVDV). The carcinoembryonic antigen (CEA) is a prevalent tumor marker expressed by a number of different cancers such as colorectal, breast, lung and ovarian carcinomas; vaccination with vaccinia virus genetically engineered to express√äCEA√ämay generate antitumoral T-cell responses.√äBVDV√äis an RNA pestivirus that may contaminate vaccines due to its presence in fetal calf serum used as a growth supplement in the tissue culture of mammalian cells used in vaccine production." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29476", "PubMed:35380920", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5295" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/415" ; obo:OGG_0000000006 "4153" ; obo:VO_0001818 "5295" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MBL2" ; rdfs:label "TBC-CEA-Contaminated W/ BVDV Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007050 obo:IAO_0000115 "A lipid-based multi-peptide cancer vaccine targeted against multiple cancers with immunopotentiating activity. Therapeutic breast/ovarian/prostate peptide cancer vaccine DPX-0907 is a lyophilized liposomal proprietary preparation comprised of 7 tumor-specific HLA-A2-restricted epitopes (TAAs): topoisomerase II alpha, B-cell receptor-associated protein 31 (CDM protein), TNF-alpha-converting enzyme (TACE/ADAM17), Abelson homolog 2 (Abl2), gamma catenin (Junction plakoglobin), epithelial discoidin domain receptor 1 (EDDR1) and integrin beta 8 subunit. Upon vaccination, the lyophilized antigen/adjuvant/liposome complex is re-suspended in Montanide 1SA51 VG to create a depot effect, thereby presenting the TAAs to the immune system for a prolonged period of time. This may stimulate a potent cytotoxic T-lymphocyte (CTL) immune response against cancer cells that express these 7 TAAs and share epitopes with the vaccine epitope peptides, resulting in tumor cell lysis. The 7 TAAs are overexpressed on the surface of breast/ovarian and prostate cancer cells and play an important role in tumor cell growth and survival." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C91077", "NCT: https://clinicaltrials.gov/ct2/show/NCT01095848", "PubMed:22862954", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5458" ; obo:OGG_0000000006 "10134", "27", "3696", "3728", "6868", "7153", "780" ; obo:VO_0001818 "5458" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: BCAP31|Gene name: TOP2A|Gene name: ADAM17|Gene name: ABL2|Gene name: JUP|Gene name: DDR1|Gene name: IGTB8" ; rdfs:label "Therapeutic Breast/Ovarian/Prostate Peptide Cancer Vaccine DPX-0907" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, obo:VO_0005484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007051 obo:IAO_0000115 "A cancer vaccine containing URLC10 (up-regulated lung cancer 10) epitopes with potential immunostimulatory and antineoplastic activities. Upon administration, URL peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against URLC10-expressing tumor cells. Up-regulated in lung and esophageal cancers, the function of URLC10 is unknown." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C74087", "NCT: https://clinicaltrials.gov/ct2/show/NCT00624182", "PubMed:29568993", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5115" ; obo:OGG_0000000006 "54742" ; obo:VO_0001818 "5115" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: LY6K" ; rdfs:label "URLC10 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4606 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007052 obo:IAO_0000115 "A cancer vaccine containing five peptide epitopes with potential immunostimulatory and antitumor activity. Peptide epitopes in this vaccine are derived from: URLC10 (up-regulated lung cancer 10), TTK (TTK protein kinase), KOC1 (IGF II mRNA Binding Protein 3) and VEGFRs (vascular endothelial growth factor receptors) 1 and 2. Upon administration, URLC10-TTK-KOC1-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, TTK, KCO1, VEGFR 1 and 2 peptides, resulting in cell lysis and decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C74088", "NCT: https://clinicaltrials.gov/ct2/show/NCT00632333", "PubMed:24708624", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5001" ; obo:OGG_0000000006 "10643", "54742", "7422" ; obo:VO_0001818 "5001" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: LY6K|Gene name: VEGFA|Gene name: IGF2BP3" ; rdfs:label "URLC10-TTK-KOC1-VEGFR1-VEGFR2 Multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005496, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5041 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007053 obo:IAO_0000115 "A highly tumor-selective vaccinia virus (vv) with an engineered double deletion (DD) of the thymidine kinase (tk) and vaccinia growth factor genes and additions of both a cytosine deaminase (CD) gene and a somatostatin receptor (SR) gene with potential oncolytic viral activity. The tk and vaccinia growth factor gene deletions in intratumorally administered vaccinia virus (vvDD-CDSR) help to restrict its replication and cytolytic activity to tumor cells with large nucleotide pools and tumor cells with activation of the EGFR-Ras pathway. Addition of the CD gene to the viral genome allows control of oncolytic viral infection through the administration of the prodrug 5-fluorocytosine (5-FC), converted by CD to the antimetabolite 5-fluorouracil (5-FU) in cells infected with this agent. Addition of the SR gene allows anatomical localization of vaccinia virus (vvDD-CDSR) through the use of octreotide scintigraphy." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74089", "NCT: https://clinicaltrials.gov/ct2/show/NCT00574977", "PubMed:27203445", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5296" ; obo:OGG_0000000006 "45091589" ; obo:VO_0001818 "5296" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: cdsR" ; rdfs:label "Vaccinia Virus DD-CDSR Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007054 obo:IAO_0000115 "A vaccine consisting of two plasmids encoding the human cytomegalovirus (CMV) tegument phosphoprotein 65 (pp65), a major internal matrix protein, and glycoprotein B (gB), an important CMV component responsible for attachment and entry into cells, with immunostimulatory properties. Vaccination with VCL-CB01 may stimulate the host immune system to mount cellular and humoral immune responses against CMV positive cells, resulting in cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61327", "NCT: https://clinicaltrials.gov/ct2/show/NCT00285259", "PubMed:22237175", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5390" ; obo:OGG_0000000006 "3077579" ; obo:VO_0001818 "5390" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: UL83" ; rdfs:label "VCL-CB01 Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005427, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007055 obo:IAO_0000115 "A live attenuated bacteria injectable vaccine used to prevent typhoid, which is caused by Salmonella typhi." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C97127", "NCT: https://clinicaltrials.gov/ct2/show/NCT03294564", "PubMed:7487253", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5322" ; obo:VO_0001818 "5322" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vi Capsular Polysaccharide Typhoid Vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0000768, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007056 obo:IAO_0000115 "A synthetic peptide vaccine consisting of a HLA-DR15-restricted human Wilms' Tumor protein-1 (WT1) peptide comprised of amino acids 124 through 138, a HLA class II-restricted WT1 peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 124-138 peptide may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. Activated helper T-cells stimulate dendritic cells, and activate the proliferation of other T-lymphoctes and B-lymphocytes. This causes tumor cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing tumor cells. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C104738", "PubMed:16220325", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5430" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5430" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "WT1 124-138 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, obo:VO_0005486, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007057 obo:IAO_0000115 "A synthetic peptide vaccine consisting of the amino acids 126 through 134 of the human Wilms' Tumor protein-1 (WT1) with potential antitumor activity. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. Vaccination with WT1 126-134 peptide vaccine may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61442", "NCT: https://clinicaltrials.gov/ct2/show/NCT01842139", "PubMed:26492414", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5089" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5089" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "WT1 126-134 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005429, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007058 obo:IAO_0000115 "A synthetic peptide vaccine consisting of a HLA-A24-restricted human Wilms' Tumor protein-1 (WT1) peptide comprised of amino acids 235 through 243, a MHC class I-restricted peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 235-243 peptide may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C104734", "PubMed:23225417", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5029" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5029" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "WT1 235-243 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007059 obo:IAO_0000115 "A synthetic peptide vaccine consisting of a HLA-DRw53-restricted human Wilms' Tumor protein-1 (WT1) peptide comprised of amino acids 247 through 261, a HLA class II-restricted WT1 peptide, with potential immunomodulating and antitumor activities. Vaccination with WT1 247-261 peptide may stimulate a CD4-positive helper T-lymphocyte-mediated immune response against WT1 expressing cells. Activated helper T-cells stimulate dendritic cells, and activate the proliferation of other T-lymphoctes and B-lymphocytes. This causes tumor cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing tumor cells. WT1, a zinc finger DNA-binding protein, is overexpressed in most types of leukemia and in a variety of solid cancers." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C104737", "PubMed:16220325", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5468" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5468" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "WT1 247-261 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, obo:VO_0005486, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007060 obo:IAO_0000115 "A cancer vaccine consisting of the DNA plasmid pNGVL4a-A encoding calreticulin (CRT) linked to a detox form of human papillomavirus (HPV) type 16 E7 antigen, with potential immunomodulating and antineoplastic activities. Upon administration, this vaccine may generate a potent cytotoxic T-lymphocyte (CTL) response against E7-expressing tumor cells, resulting in tumor cell death. For E7(detox), the amino acids in E7 at positions 24 (cysteine to glycine) and 26 (glutamic acid to glycine) were substituted. CRT, a 46 kDa protein located in the lumen of the cell's endoplasmic reticulum (ER), may potentiate MHC class I presentation of HPV-16 E7 to E7-specific CD8-positive T cells. In addition, pNGVL4a-A contains two short immunostimulatory DNA sequences (ISS) in the noncoding region, which may elicit the production of IFN- and IL-12 in transfected keratinocytes and dermal antigen presenting cells (APCs), resulting in a potent T helper cell type 1 response." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C88289", "NCT: https://clinicaltrials.gov/ct2/show/NCT00988559", "PubMed:26616223", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5011" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/123" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "5011" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HPV16 E7" ; rdfs:label "pNGVL4a-CRT/E7(detox) DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007061 obo:IAO_0000115 "An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock protein 70 (HSP70). Upon administration, this vaccine may generate potent cytotoxic CD8(+) T-cell responses against E7-expressing tumor cells, resulting in tumor cell death." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48418", "NCT: https://clinicaltrials.gov/ct2/show/NCT00121173", "PubMed:30296681", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5069" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/124" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "5069" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HPV16 E7" ; rdfs:label "pNGVL4a-Sig/E7(detox)/HSP70 DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007062 obo:IAO_0000115 "A non-infectious recombinant, quadrivalent vaccine prepared from the highly purified virus-like particles (VLPs) of the major capsid (L1) protein of human papillomavirus (HPV) Types 6, 11, 16, and 18 with immunoprophylactic activity. The immunoprohylactic efficacy of L1 VLP vaccines, such as recombinant human papillomavirus quadrivalent vaccine, appear to be mediated by the development of humoral immune responses. HPV Types 16 and 18 account for approximately 70% of cervical cancers and HPV Types 6 and 11 account for approximately 90% of genital warts." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C61087", "NCT: https://clinicaltrials.gov/ct2/show/NCT00411749", "PubMed:35997582", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5406" ; obo:OGG_0000000006 "25479185" ; obo:VO_0001818 "5406" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: L1" ; rdfs:label "Quadrivalent Human Papillomavirus (types 6, 11, 16, 18) Recombinant Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007063 obo:IAO_0000115 "A non-infectious, recombinant, nonavalent vaccine prepared from highly purified virus-like particles (VLPs) comprised of the major capsid (L1) proteins from human papillomavirus (HPV) types 6, 11, 16, 18, 31, 33, 45, 52, and 58, with active immunizing activity. Upon administration, the recombinant HPV nonavalent vaccine activates the immune system to produce antibodies against the 9 HPV types. This protects against HPV infection and HPV-related cancers. Altogether, HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58 account for the majority of the HPV types that cause cervical, vulvar, vaginal and anal cancers.√ä" ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C119664", "PubMed:26772631", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5342" ; obo:OGG_0000000006 "25479185", "7162" ; obo:VO_0001818 "5342" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: L1|Gene name: TPBG" ; rdfs:label "Recombinant Human Papillomavirus Nonavalent Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007064 obo:IAO_0000115 "A cancer vaccine comprised of a modified, replication-defective, vaccinia virus Ankara (MVA) strain encoding the tumor-associated antigens (TAAs) human papillomavirus type 16 (HPV16) subtypes E6 and E7, and human interleukin-2 (IL-2), with potential immunostimulating and antineoplastic activities. Vaccination with MVA-HPV16E6/E7-IL2 vaccine TG4001 stimulates the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing HPV16 E6 and E7, resulting in tumor cell lysis. Expression of IL-2 augments the specific CTL response against HPV16 E6- and E7-expressing tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C88326", "NCT: https://clinicaltrials.gov/ct2/show/NCT01022346", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5208" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/340" ; obo:OGG_0000000006 "1489078", "1489079" ; obo:VO_0001818 "5208" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E6|Gene name: E7" ; rdfs:label "Recombinant Vaccinia Viral Vector RO5217790 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007065 obo:IAO_0000115 "A therapeutic peptide vaccine consisting of thirteen synthetic long peptides (SLPs), which are 25-35 amino acids in size, derived from the human papillomavirus (HPV) type 16 oncoproteins E6 and E7, with potential immunostimulating and antitumor activities. Upon administration, synthetic long E6/E7 peptides vaccine HPV-01 is taken up and degraded into small pieces by dendritic cells. The processed viral epitopes are presented by dendritic cells, which may stimulate the host immune system to mount both cytotoxic T-cell lymphocyte (CTL) and helper T cell responses against HPV E6/E7-expressing tumor cells. This results in the destruction of tumor cells and leads to decreased tumor growth. The E6 and E7 oncoproteins are implicated in the tumorigenesis in a variety of cancers. The SLPs allow for optimal presentation by antigen-presenting cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C111037", "NCT: https://clinicaltrials.gov/ct2/show/NCT02128126", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5186" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/410" ; obo:OGG_0000000006 "1489078", "1489079" ; obo:VO_0001818 "5186" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E6|Gene name: E7" ; rdfs:label "Synthetic Long E6/E7 Peptides Vaccine HPV-01" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007066 obo:IAO_0000115 "A recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from Mycobacterium bovis, and the human papilloma viral (HPV) protein E7. Hsp65, similar to other members of its family of proteins, elicits a strong immune response and may be used to design vaccines against a number of different cancers. E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2811", "NCT: https://clinicaltrials.gov/ct2/show/NCT00493545", "PubMed:16691066", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5542" ; obo:OGG_0000000006 "1489079", "3329" ; obo:VO_0001818 "5542" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7|Gene name: HSPD1" ; rdfs:label "Verpasep Caltespen Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007067 obo:IAO_0000115 "A synthetic vaccine used for cancer immunotherapy also known as Ras(cis 12)-Vaccinia Vaccine, RASVAC-C is based on a mutant peptide epitope of the Ras oncoprotein at codon 12 that induces recognition and induction of tumor-specific, cell-mediated immune responses. Ras is an intracellular GTP-binding protein involved in signal transduction and regulation of proliferation and differentiation." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29401", "NCT: https://clinicaltrials.gov/ct2/show/NCT00019591", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5504" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/190" ; obo:OGG_0000000006 "3845" ; obo:VO_0001818 "5504" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KRAS" ; rdfs:label "RASVAC-C Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007068 obo:IAO_0000115 "A synthetic vaccine used for cancer immunotherapy also known as Ras(val 12)-Vaccinia Vaccine,√äRASVAC-C√äis based on a mutant peptide epitope of the Ras oncoprotein at codon 12 (valine instead of glycine) that induces recognition and induction of tumor-specific, cell-mediated immune responses. Ras is an intracellular GTP-binding protein involved in signal transduction and regulation of proliferation and differentiation.√ä" ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29402", "NCT: https://clinicaltrials.gov/ct2/show/NCT00019591", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5497" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/191" ; obo:OGG_0000000006 "3845" ; obo:VO_0001818 "5497" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KRAS" ; rdfs:label "RASVAC-V Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007069 obo:IAO_0000115 "A genetically-engineered adenovirus that contains the gene that encodes the human tumor-suppressor protein p53 with potential antineoplastic activity. Recombinant adenovirus-p53 SCH-58500 delivers p53 into tumor cells, which may result in p53-mediated cell cycle arrest and apoptosis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2423", "NCT: https://clinicaltrials.gov/ct2/show/NCT00002960", "PubMed:16082381", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5470" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/325" ; obo:OGG_0000000006 "4771", "7157", "7490" ; obo:VO_0001818 "5470" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NF2|Gene name: WT1|Gene name: TP53 (P53)" ; rdfs:label "Recombinant Adenovirus-p53 SCH-58500 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007070 obo:IAO_0000115 "An immunocytokine consisting of human pro-inflammatory cytokine tumor necrosis factor alpha (TNFalpha) fused to a human single-chain variable fragment (scFv) directed against the extra-domain B (ED-B) of fibronectin (L19), with potential immunopotentiating and antineoplastic activities. Upon adinistration, the L19 moiety of onfekafusp alfa binds to the ED-B domain of fibronectin on tumor cells in the tumor neovasculature. In turn, the TNFalpha moiety may locally induce an immune response against ED-B fibronectin-expressing tumor cells and may specifically decrease the proliferation of ED-B-expressing tumor cells. ED-B is predominantly expressed during angiogenesis and tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C166939", "NCT: https://clinicaltrials.gov/ct2/show/NCT01253837", "PubMed:12810649", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5219" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/336" ; obo:OGG_0000000006 "100136034" ; obo:VO_0001818 "5219" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: tnf-alpha" ; rdfs:label "Recombinant Human Fusion Protein L19TNFalpha Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007071 obo:IAO_0000115 "A cancer vaccine containing multiple peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from, URLC10 (up-regulated lung cancer 10), CDCA1 (cell division cycle-associated protein 1), KOC1 (IGF II mRNA Binding Protein 3). Upon administration, URLC10-CDCA1-KOC1 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing URLC10, CDCA1, KCO1 peptides, resulting in cell lysis and decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C95212", "NCT: https://clinicaltrials.gov/ct2/show/NCT00681577", "PubMed:27720136", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5350" ; obo:OGG_0000000006 "10643", "54742", "83540" ; obo:VO_0001818 "5350" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: LY6K|Gene name: NUF2|Gene name: IGF2BP3" ; rdfs:label "URLC10-CDCA1-KOC1 Multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005490, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10534 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007072 obo:IAO_0000115 "A fusion DNA vaccine containing the first domain of fragment C (FrC) of tetanus toxin (TT865-1120) (p.DOM) fused to the human Wilms' Tumor gene-1 (WT1)-derived MHC class I-binding epitope WT1.126, with potential antitumor activity. Upon vaccination with p.DOM-WT1-126 DNA and subsequent electroporation, this vaccine may induce a WT1 epitope-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing cancer cells. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. The FrC of tetanus toxin contains the MHC II-binding sequence, p30, which induces T-helper cell activation for long-lasting immunity." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C96738", "NCT: https://clinicaltrials.gov/ct2/show/NCT01334060", "PubMed:27099895", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5165" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/69" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5165" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "p.DOM-WT1-126 DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007073 obo:IAO_0000115 "A fusion DNA vaccine containing the first domain of fragment C (FrC) of tetanus toxin (TT865-1120) (p.DOM) fused to the human Wilms' Tumor gene-1 (WT1)-derived MHC class I-binding epitope WT1.37, with potential antitumor activity. Upon vaccination with p.DOM-WT1-37 DNA and subsequent electroporation, this vaccine may induce a WT1 epitope-specific cytotoxic T-lymphocyte (CTL) response against WT1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation in WT1-overexpressing cancer cells. WT1, a tumor associated antigen, is overexpressed in most types of leukemia and in a variety of solid cancers. The FrC of tetanus toxin contains the MHC II-binding sequence, p30, which induces T-helper cell activation for long-lasting immunity." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C96737", "NCT: https://clinicaltrials.gov/ct2/show/NCT01334060", "PubMed:27099895", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5471" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/61", "https://github.com/vaccineontology/VO/issues/62" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5471" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "p.DOM-WT1-37 DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007074 obo:IAO_0000115 "A cancer vaccine containing PR1, a 9 amino-acid human leukocyte antigen (HLA)-A2 restricted peptide derived from proteinase 3, with potential immunotherapeutic activity. Vaccination with PR1 leukemia peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing proteinase 3, resulting in tumor cell lysis. Often overexpressed in leukemic cells, proteinase 3 is a serine proteinase that activates progelatinase A and is involved in angiogenesis and metastasis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2235", "NCT: https://clinicaltrials.gov/ct2/show/NCT00004918", "PubMed:27654852", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5140" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/139" ; obo:OGG_0000000006 "140738" ; obo:VO_0001818 "5140" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TMEM37" ; rdfs:label "PR1 Leukemia Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007075 obo:IAO_0000115 "A vaccine made of cancer cells, parts of cancer cells, or pure tumor antigens (substances isolated from tumor cells). A tumor antigen vaccine may stimulate the body's immune system to find and kill cancer cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2341", "NCT: https://clinicaltrials.gov/ct2/show/NCT00100971", "PubMed:30348199", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5387" ; obo:VO_0001818 "5387" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Tumor Cell Derivative Vaccine" ; rdfs:subClassOf obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007076 obo:IAO_0000115 "A√äpeptide√äcancer√ävaccine√äcomprised of a√äpeptide√äderived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration,√äWT1√äpeptide√ävaccine√äOCV-501√ämay stimulate a CD4-positive helper T-lymphocyte-mediated immune response against√äWT1√äexpressing cells.√äWT1√äprotein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in some solid tumors." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C106257", "NCT: https://clinicaltrials.gov/ct2/show/NCT01961882", "PubMed:28321480", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5330" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5330" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "WT1 Peptide Vaccine OCV-501" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007077 obo:IAO_0000115 "An immunotherapeutic consisting of the recombinant fusion protein WT1-A10 combined with the adjuvant ASO1B with potential immunostimulating and antineoplastic activities. Upon administration, WT1-A10/AS01B immunotherapeutic GSK2130579AWT1 may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1-expressing tumor cells, resulting in cell lysis and the inhibition of cellular proliferation. The tumor-associated antigen WT1 (Wilms tumor protein-1) is overexpressed in most types of leukemia and in a variety of solid cancers. WT1-A10 is a 292 amino acid recombinant fusion protein consisting of a 12-mer truncated tat sequence (leader sequence) and amino acids number 2-281 of the WT1 sequence; ASO1B consists of a combination of the adjuvants monophosporyl lipd A (MPL) and Q21." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C78865", "NCT: https://clinicaltrials.gov/ct2/show/NCT00725283", "PubMed:16117707", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5354" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5354" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "WT1-A10/AS01B Immunotherapeutic GSK2130579A Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007078 obo:IAO_0000115 "A recombinant vaccinia virus encoding carcinoembryonic antigen (CEA). CEA is overexpressed in several cancer cell types, including gastrointestinal, breast, and non-small cell lung cancers. Attenuated vaccinia virus is a highly effective immunizing agent that evokes both humoral and cell-mediated responses. Vaccination with this agent may evoke a cytotoxic immune response to CEA-expressing cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2809", "NCT: https://clinicaltrials.gov/ct2/show/NCT00081848", "PubMed:7629885", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5401" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/341" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5401" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5" ; rdfs:label "Recombinant Vaccinia-CEA Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007079 obo:IAO_0000115 "Human mesenchymal stem cells (MSCs) harvested from bone marrow of healthy adult donors and expanded ex vivo, with potential immunosuppressive activity. Remestemcel-L cells are hypo-immunogenic due to lack of major histocompatibility II (MHC II) molecule expression, eliciting little, if any, host immune response upon intravenous infusion. Infusion of allogeneic MSCs may result in: a) increased production of anti-inflammatory cytokines, such as interleukin-10, prostaglandin E, and hepatocyte growth factor; b) decreased mononuclear phagocyte expression of indoleamine 2,3,-dioxygenase, which catabolizes L-tryptophan into its pro-inflammatory metabolites; and c) modulated dendritic cell (DC)maturation and disrupted activities of natural killer (NK) cells and CD8+ and CD4+ T cells. In addition, pluripotent MSCs, upon administration, may be recruited to damaged tissue sites, differentiating along specific lineages when stimulated." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C67082", "PubMed:32018062", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4993" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/353" ; obo:VO_0001818 "4993" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Remestemcel-L Vaccine" ; rdfs:subClassOf obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007080 obo:IAO_0000115 "A replication-competent oncolytic, telomerase-specific adenovirus serotype 5 (Ad5), with potential antineoplastic activity. OBP-301 contains the human telomerase reverse transcriptase (hTERT) gene promoter sequence that drives the expression of the E1A and E1B genes, and is linked to an internal ribosomal entry site (IRES). Upon administration, OBP-301 selectively infects and replicates in cancer cells that are expressing telomerase, which causes cell lysis. This adenovirus does not infect or replicate in normal, healthy cells. OBP-301 may also potentially be used as a chemosensitizer. hTERT, which encodes for the catalytic protein subunit of telomerase, is overexpressed in a variety of cancer cell types but not in normal, healthy cells. The insertion of an IRES further improves selectivity towards telomerase-expressing cancer cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C119617", "NCT: https://clinicaltrials.gov/ct2/show/NCT02293850", "PubMed:27673332", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5072" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5072" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "Telomerase-specific Type 5 Adenovirus OBP-301 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007081 obo:IAO_0000115 "A proprietary cancer DNA vaccine that contains multiple natural and modified epitopes derived from the four tumor associated antigens, CEA, HER2/neu, p53, and MAGE 2/3. OSE 2101 also includes CAP1-6D, a heteroclitic CEA analog, and PADRE, a proprietary universal T-cell epitope that serves to enhance the immunogenicity of the epitopes. This agent has been shown to elicit cytotoxic T-lymphocyte responses against tumor cells expressing these multiple epitopes." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26645", "NCT: https://clinicaltrials.gov/ct2/show/NCT02654587", "PubMed:18382135", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5528" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/72" ; obo:OGG_0000000006 "1048", "2064", "4101", "4102", "7157" ; obo:VO_0001818 "5528" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53|Gene name: CEACAM5|Gene name: ERBB2|Gene name: MAGEA2|Gene name: MAGEA3" ; rdfs:label "EP-2101 Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007082 obo:IAO_0000115 "A tumor-specific peptide encoded by patient-specific mutant p53 oncogene with potential immunostimulatory properties. The peptide (LPTGQDL) contains a frame shift mutation at amino acid position 134. It was used to pulse dendritic cells, which are then used in the adoptive immunotherapy setting and may stimulate the host immune system to mount a specific cytotoxic T lymphocyte response against tumor cells expressing the p35 mutation." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38121", "NCT: https://clinicaltrials.gov/ct2/show/NCT00049218", "PubMed:29301826", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5272" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/125", "https://github.com/vaccineontology/VO/issues/193" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "5272" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53" ; rdfs:label "PR-151 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007083 obo:IAO_0000115 "An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C95024", "NCT: https://clinicaltrials.gov/ct2/show/NCT01598454", "PubMed:26903265", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5201" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/188" ; obo:OGG_0000000006 "3265", "3845", "4893" ; obo:VO_0001818 "5201" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HRAS|Gene name: NRAS|Gene name: KRAS" ; rdfs:label "Racotumomab Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007084 obo:IAO_0000115 "A replication-defective adenovirus containing a gene that encodes the human protein L523S with potential antineoplastic activity. Upon administration, recombinant adenovirus-L523S vaccine expresses L523S, which may stimulate antibody and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing L523S. L523S is an RNA-binding protein that belongs to the KOC (K homology domain containing protein over-expressed in cancer) family of proteins. As an oncofetal protein, L523S is normally expressed in early embryonic tissues and certain normal adult tissues such as colon, fallopian tube, gall bladder, and ovary tissues but may be overexpressed in squamous cell cancers of the lung." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C49289", "NCT: https://clinicaltrials.gov/ct2/show/NCT00062907", "PubMed:16581300", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5074" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/323" ; obo:OGG_0000000006 "10643" ; obo:VO_0001818 "5074" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IGF2BP3" ; rdfs:label "Recombinant Adenovirus-L523S Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007085 obo:IAO_0000115 "A plasmid DNA encoding human L523S, an RNA-binding protein that belongs to the KOC (K homology domain containing protein overexpressed in cancer) family, with potential antineoplastic activity. Vaccination with L523S DNA may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells that express the L523S protein. As an oncofetal protein, L523S is normally expressed in early embryonic tissue, but is overexpressed in certain cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C49290", "NCT: https://clinicaltrials.gov/ct2/show/NCT00062907", "PubMed:12750279", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5156" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/327" ; obo:OGG_0000000006 "10643" ; obo:VO_0001818 "5156" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IGF2BP3" ; rdfs:label "Recombinant DNA-L523S Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007086 obo:IAO_0000115 "A peptide vaccine preparation, containing recombinant human epidermal growth factor (rEGF) linked to the Neisseria meningitidis-derived recombinant immunogenic carrier protein P64k (rP64k) and mixed with the immunoadjuvant Montanide ISA 51, with potential active immunotherapy activity. Recombinant human EGF-rP64K/Montanide ISA 51 vaccine may trigger a humoral immune response against vaccine rEGF and rP64K and, so, against endogenous EGF. Antibody-mediated inhibition of endogenous EGF binding to its receptor, epithelial growth factor receptor (EGFR), may result in the inhibition of tumor cell proliferation." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C70674", "NCT: https://clinicaltrials.gov/ct2/show/NCT00516685", "PubMed:29661145", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5190" ; obo:OGG_0000000006 "25003478" ; obo:VO_0001818 "5190" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: LV28_RS26095 transcriptional regulator RegF" ; rdfs:label "Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007087 obo:IAO_0000115 "An allogeneic lung cancer vaccine with potential immunostimulating and antineoplastic activities. Derived from allogeneic lung tumor cells, tergenpumatucel-L is engineered to express the murine alpha-1,3-galactosyltransferase (GalT), an enzyme humans lack. GalT catalyzes the expression of foreign alpha-1,3-galactosyl (alpha-gal) carbohydrate epitopes in glycoproteins and in glycolipids on the cell membranes of the allogeneic lung tumor cells present in the vaccine, essentially producing a 'xenograft'. The hyperacute rejection involves pre-existing human anti-alpha-gal antibodies that bind the foreign alpha-gal epitopes expressed by the vaccine tumor cell xenograft, resulting in complement-mediated cytotoxicity (CMC) and antibody-dependent cell-mediated cytotoxicity (ADCC) towards endogenous lung tumor cells with unmodified carbohydrate epitopes." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C66985", "NCT: https://clinicaltrials.gov/ct2/show/NCT02460367", "PubMed:28238782", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5527" ; obo:VO_0001818 "5527" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Tergenpumatucel-L Vaccine" ; rdfs:subClassOf obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007088 obo:IAO_0000115 "A proprietary, allogeneic tumor cell vaccine expressing a recombinant secretory form of the heat shock protein gp96 fusion (gp96-Ig) with potential antineoplastic activity. Upon administration of viagenpumatucel-L, the irradiated live tumor cells continuously secrete gp96-Ig along with its chaperoned tumor associated antigens (TAAs) into the blood stream, thereby activating antigen presenting cells, natural killer cells and priming potent cytotoxic T lymphocytes (CTLs) to respond against TAAs on the endogenous tumor cells. Furthermore, this vaccine may induce long-lived memory T cells that could fight recurring cancer cells. gp96-Ig is constructed by replacing the KDEL retention sequence of gp96, normally an endoplasmatic reticulum-resident chaperone peptide, with the Fc portion of mouse and human IgG1." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61073", "NCT: https://clinicaltrials.gov/ct2/show/NCT02439450", "PubMed:27364122", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5513" ; obo:OGG_0000000006 "7184" ; obo:VO_0001818 "5513" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HSP90B1" ; rdfs:label "Viagenpumatucel-L Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007089 obo:IAO_0000115 "A cancer vaccine consisting of a mixture of a murine lymphoma-derived idiotype and interleukin-2 (IL-2) encapsulated in dimyristoylphosphatidylcholine liposomes. The use of a liposomal carrier confers immunogenicity to the naturally non-immunogenic idiotype." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2783", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5541" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/74" ; obo:OGG_0000000006 "107653060" ; obo:VO_0001818 "5541" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IL12" ; rdfs:label "Oncovax-ID/IL-2 Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007090 obo:IAO_0000115 "A lipid depot-based therapeutic cancer vaccine composed of survivin epitopes, a universal T Helper peptide and a polynucleotide adjuvant encapsulated in liposomes and then formulated in the hydrophobic carrier Montanide ISA51 VG, with potential immunopotentiating and antineoplastic activities. Upon injection of the maveropepimut-S, a depot is created at the injection site from which the antigens and adjuvant are released. This vaccine may elicit a long lasting cellular response against survivin-expressing cancers, resulting in a decrease in tumor cell proliferation and an induction of tumor cell death. Survivin, a member of the inhibitor of apoptosis (IAP) family expressed during embryonic development, is upregulated in a variety of human cancers while absent in most normal adult cells; its expression in tumors is associated with a more aggressive phenotype, decreased survival, and increased resistance to chemotherapy." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C97951", "NCT: https://clinicaltrials.gov/ct2/show/NCT02323230", "PubMed:26405584", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5371" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/364" ; obo:OGG_0000000006 "373110" ; obo:VO_0001818 "5371" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Survivin" ; rdfs:label "Survivin Antigen Vaccine DPX-Survivac" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007091 obo:IAO_0000115 "A vaccine consisting of lymphoma-specific immunoglobulin that is not conjugated to a carrier molecule. Vaccination with unconjugated lymphoma Ig Id may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against lymphoma cells, resulting in decreased tumor growth.√ä" ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2821", "PubMed:18715553", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5046" ; obo:VO_0001818 "5046" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Unconjugated Lymphoma Ig Id Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007092 obo:IAO_0000115 "A peptide cancer vaccine consisting of peptides derived from the melanoma antigen NA-17, the human leukocyte antigen HLA-A2-restricted human melanoma antigen 3 (MAGE-3.A2) and the cancer-testis antigen (NY-ESO-1), with potential immunostimulating and antineoplastic activities. Upon administration, the NA-17/MAGE-3.A2/NY-ESO-1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing NA-17, MAGE-3.A2 and NY-ESO-1, resulting in tumor cell lysis. The tumor-associated antigens (TAAs) NA-17, MAGE-3.A2 and NY-ESO-1 are overexpressed in a variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C96042", "NCT: https://clinicaltrials.gov/ct2/show/NCT01308294", "PubMed:25941588", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5305" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/48" ; obo:OGG_0000000006 "1485", "4102" ; obo:VO_0001818 "5305" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3|Gene name: CTAG1B" ; rdfs:label "NA-17/MAGE-3.A2/NY-ESO-1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007093 obo:IAO_0000115 "A peptide cancer vaccine comprised of human leukocyte antigen HLA-A2-restricted peptide derived from a metastatic melanoma cell line of patient NA17, with potential immunomodulating and antineoplastic activity. NA17. A2 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumors that express this antigen, which may result in a reduction in tumor size. This NA17 specific antigen, encoded by an intron sequence of N-acetylglucosaminyltransferase V (GnT-V) gene, is expressed in about 50% of melanomas." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2680", "NCT: https://clinicaltrials.gov/ct2/show/NCT01307618", "PubMed:16133111", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5323" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/49" ; obo:OGG_0000000006 "107653060", "2315", "4102", "6490" ; obo:VO_0001818 "5323" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IL12|Gene name: MAGEA3|Gene name: MLANA|Gene name: PMEL" ; rdfs:label "NA17.A2 peptide vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007094 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with a peptide derived from the tumor associated antigen human cancer-testis antigen NY-ESO-1 (NY-ESO-1(157-165)), with potential immunostimulatory and antineoplastic activities. Upon administration, the NY-ESO-1(157-165) peptide-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount both an anti-tumoral cytotoxic T-lymphocyte (CTL) and an antibody-mediated immune response against NY-ESO-1-expressing tumor cells, which may result in tumor cell lysis. NY-ESO-1 is expressed both in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C114380", "NCT: https://clinicaltrials.gov/ct2/show/NCT00313508", "PubMed:16311731", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5100" ; obo:OGG_0000000006 "1485", "2315", "4102", "6490", "7299" ; obo:VO_0001818 "5100" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3|Gene name: MLANA|Gene name: PMEL|Gene name: CTAG1B|Gene name: TYR" ; rdfs:label "NY-ESO-1(157-165) Peptide-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007095 obo:IAO_0000115 "A cell-based cancer vaccine composed of dendritic cells (DC) pulsed with peptides derived from the tumor-associated antigens human cancer/testis antigen NY-ESO-1 and melanoma antigen recognized by T-cells (MART-1/Melan-A), with potential immunostimulatory and antineoplastic activities. Upon administration, the NY-ESO-1/MART-1 peptide-pulsed DC vaccine may stimulate the immune system to mount an anti-tumor cytotoxic T-lymphocyte (CTL) response against NY-ESO-1/MART-1-expressing tumor cells, which may result in tumor cell lysis. NY-ESO-1 is expressed both in normal testes and on the surfaces of various tumor cells. MART-1 is expressed by melanoma cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C120129", "NCT: https://clinicaltrials.gov/ct2/show/NCT00798629", "PubMed:16311731", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5366" ; obo:OGG_0000000006 "1485", "2315" ; obo:VO_0001818 "5366" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B|Gene name: MLANA" ; rdfs:label "NY-ESO-1/MART-1 Peptide-pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007096 obo:IAO_0000115 "A cancer√ävaccine√äconsisting of√äPEP-3, a synthetic peptide encompassing a tumor-specific mutated segment of the epidermal growth factor receptor type vIII (EGFRvIII), conjugated to the naturally-occurring immunoadjuvant keyhole limpet hemocyanin (KLH) with potential immunostimulating and antineoplastic activities. Upon administration,√äPEP-3-KLH√äconjugate√ävaccine√ämay induce a cytotoxic immune response against tumor cells that overexpress EGFRvIII; this antitumoral immune response may involve antibody-dependent cellular cytotoxicity (ADCC)." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C74070", "NCT: https://clinicaltrials.gov/ct2/show/NCT00626015", "PubMed:14519652", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5480" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/117" ; obo:OGG_0000000006 "1956" ; obo:VO_0001818 "5480" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: EGFR" ; rdfs:label "PEP-3-KLH Conjugate Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007097 obo:IAO_0000115 "A whole cell vaccine derived from a distinct subset of dendritic cells (DCs) with a plasma cell-like morphology that exhibits immunomodulating activity. Plasmacytoid dendritic cells (pDCs) express a characteristic set of surface markers, such as CD123 (interleukin-3 receptor alpha chain), BDCA-2 (blood dendritic cell antigen 2; CD303) and BDCA-4 (CD304), as well as intracellular toll-like receptors 7 and 9. Upon stimulation, the activated pDCs produce substantial amounts of interferon (IFN) alpha, and to a lesser degree IFN-beta, as well as other cytokines and chemokines, such as tumor necrosis factor alpha and interleukins 1, 6 and 8. In addition, these pDCs, directly or indirectly stimulate T-cells, B-cells and natural killer cells. This may potentially lead to increased immunity against tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C103192", "NCT: https://clinicaltrials.gov/ct2/show/NCT01690377", "PubMed:30049538", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5006" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/121" ; obo:OGG_0000000006 "170482", "3598", "51284", "54106", "8829" ; obo:VO_0001818 "5006" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IL13RA2|Gene name: CLEC4C|Gene name: NRP1|Gene name: TLR9|Gene name: TLR7" ; rdfs:label "Plasmacytoid Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007098 obo:IAO_0000115 "rime/boost vaccination proved to be of no advantage or even detrimental in therapeutic settings in B16F1 and transgenic adenocarcinoma of the mouse prostate (TRAMP) models, respectively" ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "PubMed:23539449", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4074" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/140" ; obo:VO_0001818 "4074" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "prime/boost DC-TRP-2 melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007099 obo:IAO_0000115 "A viral vaccine comprised of a√ärecombinant√äfowlpox√ävector construct encoding a modified epitope of the melanoma antigen glycoprotein 100 (gp100), ES-2092M(gp100), containing an endoplasmic reticulum signal sequence targeted to the endoplasmic reticulum apparatus. Vaccination with√ärecombinant√äfowlpox-gp100p209√ävaccine may stimulate the host immune system more efficiently to mount a cytotoxic T lymphocyte response against tumor cells expressing the gp100 antigen." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2806", "NCT: https://clinicaltrials.gov/ct2/show/NCT00080353", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5274" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5274" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)" ; rdfs:label "Recombinant Fowlpox-gp100p209 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007100 obo:IAO_0000115 "A√ävaccine√äconsisting of a replication-defective√ärecombinant√äfowlpox√ävirus that encodes for the murine melanoma antigen glycoprotein 100 (mgp100) with potential antineoplastic activity. Vaccination with√ärecombinant√äfowlpox-mgp100√ävaccine√ämay stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2805", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5499" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/332" ; obo:VO_0001818 "5499" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Recombinant Fowlpox-Mgp100 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007101 obo:IAO_0000115 "A recombinant fowlpox virus vaccine with potential antineoplastic activity. Binding to the melanoma antigen tyrosinase, recombinant fowlpox-tyrosinase vaccine generates cellular immune responses against melanoma cells expressing the tyrosinase antigen; this effect is enhanced by the co-administration of interleukin 2 (IL-2). Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2807", "NCT: https://clinicaltrials.gov/ct2/show/NCT00054535", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5518" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/335" ; obo:OGG_0000000006 "7299" ; obo:VO_0001818 "5518" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase" ; rdfs:label "Recombinant Fowlpox-Tyrosinase Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007102 obo:IAO_0000115 "A recombinant chaperone-peptide complex-based vaccine composed of a complex between heat shock protein hsp110 and the human melanoma-associated antigen gp100, with potential antineoplastic activity. Upon vaccination, recombinant hsp110-gp100 chaperone complex activates the immune system to exert a cytotoxic T cell immune response and antigen-specific interferon-gamma production against gp100-overexpressing cancer cells. Gp100, is overexpressed in a variety of cancer cell types. Hsp110, binds to and chaperones full-length proteins during heat shock; as an immunoadjuvant it is able to enhance an immune response against antigen(s) and stimulate T-lymphocyte activation." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C103830", "NCT: https://clinicaltrials.gov/ct2/show/NCT01744171", "PubMed:12750279", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5359" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5359" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)" ; rdfs:label "Recombinant Human Hsp110-gp100 Chaperone Complex Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007103 obo:IAO_0000115 "A recombinant vaccinia virus encoding a modified peptide of the gp100 melanoma-melanocyte antigen with potential use in cancer immunotherapy. gp100 human antigen is a wild type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas. gp100p209 is a fragment epitope of gp100 in which the threonine in position 2 is replaced with methionine; this modification may stimulate tumor infiltrating lymphocytes (TIL) more efficiently.√ä" ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29566", "NCT: https://clinicaltrials.gov/ct2/show/NCT00116597", "PubMed:15133631", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5393" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/344" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5393" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)" ; rdfs:label "Recombinant Vaccinia-gp100:209-217 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007104 obo:IAO_0000115 "A√ärecombinant√ävaccinia√ävirus encoding a modified peptide of the gp100 melanoma-melanocyte antigen with potential use in cancer immunotherapy. gp100 human antigen is a wild type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas. This√ärecombinant√ävaccinia√äMgp100√äencodes a fragment epitope of gp100 bearing 2 amino acids substitution; T->M at position 210 and 288 A ->V at position 210. This modification may stimulate tumor infiltrating lymphocytes (TIL) more efficiently." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C51978", "PubMed:12912944", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5505" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/346" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5505" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)" ; rdfs:label "Recombinant Vaccinia-Mgp100 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007105 obo:IAO_0000115 "A cancer vaccine consisting of an inactivated recombinant vaccinia virus encoding epitope peptides derived from melanoma-related HLA-A2-restricted tumor-associated antigens (TAAs), including Melan-A(27-35), gp100(280-288) and tyrosinase(1-9), and two co-stimulatory B7 proteins, B7.1 (CD80) and B7.2 (CD86). Upon administration, recombinant vaccinia-multiepitope melanoma peptides-B7.1-B7.2 vaccine may stimulate a cytotoxic T-lymphocyte response against melanoma cells that express TAAs which share epitopes with the epitope peptides expressed by the vaccine viral vector, resulting in tumor cell lysis; vaccine viral vector-expressed co-stimulatory proteins B7.1 and B7.2 may enhance the cytotoxic T-lymphocyte immune response to the TAAs." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48638", "PubMed:30626434", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5232" ; obo:OGG_0000000006 "12524", "2315", "6490", "941" ; obo:VO_0001818 "5232" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Cd86|Gene name: MLANA-Dupli|Gene name: CD80|Gene name: gp100 (PMEL)" ; rdfs:label "Recombinant Vaccinia-Multiepitope Melanoma Peptides-B7.1-B7.2 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007106 obo:IAO_0000115 "A recombinant vaccinia virus encoding the melanocyte differentiation antigen tyrosinase-related protein-1 (TRP-1) with potential use in cancer immunotherapy." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29564", "PubMed:19047169", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5063" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/352" ; obo:OGG_0000000006 "22178" ; obo:VO_0001818 "5063" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TRP-1" ; rdfs:label "Recombinant Vaccinia-TRP1 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007107 obo:IAO_0000115 "A vaccine adjuvant consisting of a plasmid DNA encoding sargramostim (a granulocyte macrophage-colony stimulating factor). Upon administration, expressed sargramostim may stimulate a cytotoxic T cell response enhancing the host immune response to a concomitantly administered melanoma vaccine." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2430", "NCT: https://clinicaltrials.gov/ct2/show/NCT01216436", "PubMed:26241951", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5194" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/360" ; obo:OGG_0000000006 "1493", "8784" ; obo:VO_0001818 "5194" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTLA4|Gene name: TNFRSF18" ; rdfs:label "Sargramostim Plasmid DNA Melanoma Vaccine Adjuvant" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007108 obo:IAO_0000115 "A recombinant plasmid DNA vaccine that encodes two peptides, tyrosinase 207√ê216 and tyrosinase 1√ê17, both of which are derived from human tyrosinase." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00023647", "PubMed:12833467", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4002" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/406" ; obo:VO_0001818 "4002" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Synchotrope TA2M Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007109 obo:IAO_0000115 "A recombinant plasmid DNA vaccine encoding epitopes of tyrosinase with potential antineoplastic activity. Synchrotope TA2M vaccine contains a plasmid encoding 2 epitopes, amino acid sequences 207-216 and 1-17 of tyrosinase, a protein frequently expressed by melanoma cells. Vaccination with the TA2M plasmid DNA vaccine may induce the production of anti-tyrosinase antibodies as well as elicit a cytotoxic T-lymphocyte (CTL) response against tyrosinase-expressing tumor cells, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2650", "NCT: https://clinicaltrials.gov/ct2/show/NCT00023647", "PubMed:12833467", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5218" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/407" ; obo:OGG_0000000006 "7299" ; obo:VO_0001818 "5218" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase" ; rdfs:label "Synchrotope TA2M Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007110 obo:IAO_0000115 "A bivalent DNA vaccine encoding epitopes for both Melan-A (MART-1) and tyrosinase with potential antineoplastic activity. Synchrovax SEM plasmid DNA vaccine contains a plasmid pSEM that encodes 4 epitopes: Melan-A (26-35), Melan-A (31-96), tyrosinase (1-9), and tyrosinase (369-377). Both Melan-A and tyrosinase are tumor antigens associated with melanoma. Vaccination with this plasmid DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) responses against cells expressing either or both of these antigens, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28549", "NCT: https://clinicaltrials.gov/ct2/show/NCT00033228", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5506" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/408" ; obo:OGG_0000000006 "2315", "7299" ; obo:VO_0001818 "5506" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MLANA-Dupli|Gene name: Tyrosinase" ; rdfs:label "Synchrovax SEM Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007111 obo:IAO_0000115 "A cancer vaccine containing synthetic epitope peptides derived from melanoma tumor-associated antigens (TAAs), including melanoma-melanocyte antigen gp100(280-288), melanoma-associated antigen tyrosinase(1-9), and melanoma-associated antigen melan-A(27-35). Upon administration, synthetic melanoma-associated antigens vaccine may stimulate a cytotoxic T-lymphocyte immune response against melanoma cells that express TAAs which share epitopes with the vaccine epitope peptides, resulting in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48639", "NCT: https://clinicaltrials.gov/ct2/show/NCT00116597", "PubMed:11874634", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5217" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/411" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5217" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PMEL - obsolete" ; rdfs:label "Synthetic Melanoma-Associated Antigens Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007112 obo:IAO_0000115 "A RNA-lipoplex (RNA-LIP)-based cancer vaccine containing four naked ribonucleic acid (RNA)-drug products (DPs) RBL001.1, RBL002.2, RBL003.1, and RBL004.1 encoding the four melanoma-associated antigens (MAAs), the cancer-testis antigen NY-ESO-1, the human melanoma-associated antigen A3 (MAGE-A3), tyrosinase, and putative tyrosine-protein phosphatase (TPTE), encapsulated in liposomes, with potential antineoplastic activity. Upon intravenous administration of the tetravalent RNA-lipoplex cancer vaccine BNT111, the liposomes protect the RNA from degradation in the bloodstream, travel to the spleen and are taken up by antigen-presenting cells (APCs). The RNA is translocated to the cytoplasm and translated into the four tumor-associated proteins. The expressed proteins are processed and the human leukocyte antigen (HLA)-peptide complexes are presented to the immune system. This results in the production of various pro-inflammatory cytokines and induces antigen-specific CD8+ and CD4+ T-cell responses against the four selected MAAs NY-ESO-1, MAGE-A3, tyrosinase, and TPTE." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C122396", "NCT: https://clinicaltrials.gov/ct2/show/NCT02410733", "PubMed:21093980", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5114" ; obo:OGG_0000000006 "416115" ; obo:VO_0001818 "5114" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MAGE-1" ; rdfs:label "Tetravalent RNA-lipoplex Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007113 obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "PubMed:23090079", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4004" ; obo:OGG_0000000006 "2315", "6409", "7299" ; obo:VO_0001818 "4004" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: MLANA|Gene name: PMEL|Gene name: Tyrosinase" ; rdfs:label "TLR-9/GM Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007114 obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "PubMed:23509826", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4075" ; obo:VO_0001818 "4075" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "TriMixDC-MEL Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007115 obo:IAO_0000115 "A recombinant peptide consisting of amino acid residues 180 to 188 of the tyrosinase-related protein 2 (TRP2). Expressed by cells of melanocyte origin, TRP2 is an enzyme involved in the process that converts tyrosinase to melanin pigments. Vaccination with TRP-2: 180-188 peptide may induce cytotoxic T lymphocyte (CTL) responses to melanoma cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2815", "NCT: https://clinicaltrials.gov/ct2/show/NCT00022438", "PubMed:16906394", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5325" ; obo:OGG_0000000006 "1638" ; obo:VO_0001818 "5325" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TRP-2" ; rdfs:label "TRP-2: 180-188 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007116 obo:IAO_0000115 "A recombinant peptide consisting of amino acid residues 1 to 9 of the tyrosinase-related protein 1 (TRP1). Expressed by cells of melanocyte origin, TRP1 is an enzyme involved in the process that converts tyrosinase to melanin pigments. Vaccination with TRP1(0RF3):1-9 may stimulate cytotoxic T cell responses to melanoma cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2816", "NCT: https://clinicaltrials.gov/ct2/show/NCT00019383", "PubMed:8027058", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5487" ; obo:OGG_0000000006 "22178" ; obo:VO_0001818 "5487" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TRP-1" ; rdfs:label "TRP1(0RF3):1-9 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007117 obo:IAO_0000115 "A peptide vaccine containing a tyrosinase epitope conjugated with keyhole lymphocyte hemocyanin (KLH) with potential antineoplastic activity. Tyrosinase, one of the melanoma differentiation antigens, is the rate-limiting enzyme for melanin synthesis. This tyrosine epitope is conjugated with KLH, which serves as an immunostimulant and a hapten carrier, to enhance immune recognition. Vaccination with tyrosinase-KLH peptide vaccine may produce anti-tyrosinase antibodies as well as elicit a cytotoxic T lymphocyte (CTL) response against cells expressing tyrosinase antigen, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2384", "NCT: https://clinicaltrials.gov/ct2/show/NCT00028431", "PubMed:21143299", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5060" ; obo:OGG_0000000006 "7299" ; obo:VO_0001818 "5060" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase" ; rdfs:label "Tyrosinase-KLH Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007118 obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "PubMed:14581425", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3999", "tyrosinase240-251s, 368-376d vaccine" ; obo:VO_0001818 "3999" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "tyrosinase240-251S, 368-376D Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007119 obo:IAO_0000115 "Immunotherapy with√äVMCL√äwas not associated with a statistically significant improvement in OS or RFS, with CIs not ruling out important gains from such treatment." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "PubMed:12377961", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4007" ; obo:VO_0001818 "4007" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "vaccinia melanoma cell lysates (VMCL) vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007120 obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "PubMed:3155379", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4023" ; obo:VO_0001818 "4023" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Vaccinia Melanoma Oncolysates (VMO) Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007121 obo:IAO_0000115 "A recombinant vaccinia virus that encodes granulocyte-macrophage colony stimulating factor (GM-CSF). By activating T-cells and macrophages, vaccination with recombinant vaccinia GM-CSF may enhance the host immune system response to poorly immunogenic tumors, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2674", "NCT: https://clinicaltrials.gov/ct2/show/NCT00002817", "PubMed:8894677", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5508" ; obo:OGG_0000000006 "12981" ; obo:VO_0001818 "5508" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Csf2-Mouse" ; rdfs:label "Vaccinia-GM-CSF Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007122 obo:IAO_0000115 "A vaccine consisting of recombinant vaccinia virus, based on the modified vaccinia virus Ankara (MVA) that encodes the melanoma-associated antigen tyrosinase. Vaccination with vaccinia-tyrosinase may stimulate the host immune system to mount a cytotoxic T-cell response against tumor cells expressing tyrosinase. Tyrosinase is a melanoma-specific differentiation agent that catalyzes the synthesis of the melanin precursor L-3,4-dihydroxyphenylalanine (L-DOPA)." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2531", "NCT: https://clinicaltrials.gov/ct2/show/NCT00019734", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5223" ; obo:OGG_0000000006 "7299" ; obo:VO_0001818 "5223" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase" ; rdfs:label "Vaccinia-Tyrosinase Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007123 obo:IAO_0000115 "A plasmid DNA vaccine, encoding an epitope of mouse tyrosinase, with potential antineoplastic activity. Administered via intramuscular electroporation, vaccination with xenogeneic tyrosinase DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) immune responses against melanoma cells that express tyrosinase, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C68839", "NCT: https://clinicaltrials.gov/ct2/show/NCT00471133", "PubMed:4019903", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5416" ; obo:OGG_0000000006 "7299" ; obo:VO_0001818 "5416" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase" ; rdfs:label "Xenogeneic Tyrosinase DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007124 obo:IAO_0000115 "A recombinant replication-defective adenovirus which encodes the gene for the cytokine human interferon-beta (IFN-beta). Once inserted into and replicating in host tumor cells, recombinant adenovirus-hIFN-beta expresses human IFN-beta, which may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce caspase-mediated tumor cell apoptosis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C28550", "NCT: https://clinicaltrials.gov/ct2/show/NCT00066404", "PubMed:19893592", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5510" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/321" ; obo:OGG_0000000006 "3456" ; obo:VO_0001818 "5510" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IFNB1" ; rdfs:label "Recombinant Adenovirus-hIFN-beta Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005491, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:MONDO_0005065 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007125 obo:IAO_0000115 "A modified recombinant nonapeptide (LMLGEFLKL) derived from the anti-apoptosis protein survivin with potential immunopotentiating and antineoplastic activities. Upon administration, survivin Sur1M2 peptide vaccine may elicit humoral and cellular immune responses against survivin-expressing cancers, resulting in decreased tumor cell proliferation and tumor cell death. The survivin protein inhibits caspase activation and apoptosis; it is undetectable in normal adult tissues but is expressed by several human cancers including lung, colon, breast, pancreas, and prostate cancer as well as hematopoietic malignancies and skin cancers." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C71741", "NCT: https://clinicaltrials.gov/ct2/show/NCT00499577", "PubMed:29057249", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5265" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/365" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5265" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "Survivin Sur1M2 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007126 obo:IAO_0000115 "A vaccine consisting of myeloma-specific immunoglobulin that is not conjugated to a carrier molecule. Vaccination with unconjugated myeloma Ig Id may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against myeloma cells, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2822", "NCT: https://clinicaltrials.gov/ct2/show/NCT00001561", "PubMed:4108872", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5391" ; obo:VO_0001818 "5391" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Unconjugated Myeloma Ig Id Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007127 obo:IAO_0000115 "A peptide vaccine comprised of an epitope of human Wilms tumor 1 (WT-1) with potential antineoplastic activity. WT-1, a transcription factor, is overexpressed in most types of leukemia and in some solid cancers. Vaccination with the WT-1 analog peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against WT-1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C64635", "NCT: https://clinicaltrials.gov/ct2/show/NCT01827137", "PubMed:25802083", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5341" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5341" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "WT1 Analog Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007128 obo:IAO_0000115 "A peptide cancer vaccine comprised of a peptide derived from Wilms tumor gene 1 (WT1) protein, with potential immunomodulating and antineoplastic activities. Upon administration, WT2725 may induce a specific cytotoxic T-lymphocyte (CTL) response against WT1-overexpressing tumor cells. WT1 protein, a zinc finger DNA-binding protein, is overexpressed in leukemic cells and in a vast number of non-hematological solid tumors." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C102751", "NCT: https://clinicaltrials.gov/ct2/show/NCT01621542", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5027" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5027" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "WT1 Peptide Vaccine WT2725" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007129 obo:IAO_0000115 "A cancer vaccine containing immunogenic, HLA-A2-specific epitopes derived from X-box√êbinding protein 1-unspliced (XBP1-US), XBP1-spliced (SP), syndecan-1 (CD138), and CS1 (CD2 subset 1, CRACC, SLAMF7, CD319) with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, XBP1-US/XBP1-SP/CD138/CS1 multipeptide vaccine PVX-410 may stimulate the immune system to induce a cytotoxic T-lymphocyte response against the four myeloma-specific antigens. The tumor associated antigens (TAAs) XBP1-US, XBP1-SP, CD138 and CS1, are overexpressed on the surface of multiple myeloma (MM) cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C103823", "NCT: https://clinicaltrials.gov/ct2/show/NCT01718899", "PubMed:30128502", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5415" ; obo:OGG_0000000006 "22433", "57823", "6382" ; obo:VO_0001818 "5415" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Xbp1|Gene name: SDC1|Gene name: SLAMF7" ; rdfs:label "XBP1-US/XBP1-SP/CD138/CS1 Multipeptide Vaccine PVX-410" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007130 obo:IAO_0000115 "A cancer vaccine consisting of autologous dendritic cells (DCs) loaded with autologous, lethally irradiated cancer cells and mixed with the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulatory and antineoplastic activities. Upon vaccination, ovapuldencel-T may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against the repertoire of tumor associated antigens (TAAs) found in the irradiated cancer cells. GM-CSF enhances the activation of dendritic cells (DCs) and promotes antigen presentation to both B- and T-lymphocytes." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C113651", "NCT: https://clinicaltrials.gov/ct2/show/NCT02033616", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5481" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/71" ; obo:VO_0001818 "5481" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Ovapuldencel-T Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007131 obo:IAO_0000115 "A cancer vaccine comprised of synthetic peptides corresponding to naturally-occurring peptides derived from ovarian cancer cell antigens. Ovarian cancer peptide vaccine may elicit a cytotoxic T-cell response against tumor cells expressing the related ovarian cancer cell antigens." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C48414", "NCT: https://clinicaltrials.gov/ct2/show/NCT00091273", "PubMed:20445345", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5502" ; obo:VO_0001818 "5502" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Ovarian Cancer Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007132 obo:IAO_0000115 "A cancer vaccine containing autologous dendritic cells (DCs) that are transfected with mRNAs extracted from amplified ovarian cancer stem cells, and mRNAs of the universal tumor antigens human telomerase reverse transcriptase (hTERT) and survivin with potential immunostimulatory and antineoplastic activities. Upon administration, ovarian cancer stem cell/hTERT/survivin mRNAs-loaded autologous DC-006 vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against ovarian cancer cells expressing hTERT, survivin, and specific ovarian cancer stem cell antigens. hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types, playing key roles in tumor cell growth and survival. Ovarian cancer stem cells contain a specific range of antigens that are essential for the neoplastic growth and survival of ovarian cancer cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C96739", "NCT: https://clinicaltrials.gov/ct2/show/NCT01334047", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5403" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5403" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "Ovarian Cancer Stem Cell/hTERT/Survivin mRNAs-loaded Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007133 obo:IAO_0000115 "A dendritic cell (DC)-based cancer vaccine composed of autologous dendritic cells (DCs) activated with an ovarian tumor cell lysate containing tumor-associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, the ovarian tumor antigen-activated autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells expressing ovarian tumor cell-specific antigens, which may result in ovarian tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C115105", "NCT: https://clinicaltrials.gov/ct2/show/NCT02107950", "PubMed:22862954", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5280" ; obo:OGG_0000000006 "3696", "3728", "780" ; obo:VO_0001818 "5280" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ITGB8|Gene name: JUP|Gene name: DDR1" ; rdfs:label "Ovarian Tumor Antigen-activated Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007134 obo:IAO_0000115 "A peptide vaccine consisting of 10 synthetic long peptides (SLPs), 25-30 amino acids in size and derived from the middle portion of p53 (amino acids 70-251), mixed with the adjuvant Montanide ISA-51 with potential immunostimulatory and antitumor activities. Upon administration, p53 synthetic long peptide (70-251) vaccine may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against p53-expressing tumor cells. p53, a tumor associated antigen (TAA), may be overexpressed in variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C82420", "NCT: https://clinicaltrials.gov/ct2/show/NCT00844506", "PubMed:26334096", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5278" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/59" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "5278" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53" ; rdfs:label "P53-Synthetic Long Peptides Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007135 obo:IAO_0000115 "A cell-based cancer vaccine with potential antineoplastic activity. PA-1-STK ovarian carcinoma vaccine is produced by transducing the ovarian cancer cell line, PA-1, with the herpes simplex thymidine kinase (HSV-tk) gene, resulting in a cell line, PA-1-STK, that permanently expresses the HSV tk gene. Upon transfection into malignant cells, this vaccine is capable of sensitizing tumor cells in response to an antiviral drug such as ganciclovir, which is readily phosphorylated by the TK enzyme to its active form. Administration of ganciclovir following PA-1 STK transfection results in enhanced cytotoxicity of the transfected tumor cells. Additionally, adjacent non-transfected cells are also killed by the activated antiviral drug, a phenomenon referred to as the bystander effect that occurs with this type of suicide-gene transfer technique." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2428", "NCT: https://clinicaltrials.gov/ct2/show/NCT00006216", "PubMed:7578411", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5245" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/57" ; obo:OGG_0000000006 "79447" ; obo:VO_0001818 "5245" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PAGR1" ; rdfs:label "PA-1-STK Ovarian Carcinoma Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007136 obo:IAO_0000115 "An oncolytic thymidine kinase (TK)-deleted vaccinia poxvirus expressing human GM-CSF (hGM-CSF) with antineoplastic activity. Upon intratumoral or intravenous administration, pexastimogene devacirepvec selectively infects and lyses tumor cells. While vaccinia displays a natural tumor cell tropism, deletion of the TK gene increases the tumor selectivity of vaccinia by limiting viral replication to cells expressing high levels of TK, such as certain cancer cells. hGM-CSF expression by this agent helps recruit antigen presenting cells (APCs), such as dendritic cells (DCs) and macrophages, to virally infected tumor cells, thereby initiating an antitumoral immune response." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C71533", "NCT: https://clinicaltrials.gov/ct2/show/NCT02562755", "PubMed:31413923", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5078" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/119" ; obo:OGG_0000000006 "1437" ; obo:VO_0001818 "5078" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: hGM-CSF" ; rdfs:label "Pexastimogene-devacirepvec Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007137 obo:IAO_0000115 "A plasmid DNA vaccine containing mammalian expression vector pUMVC3, encoding epitopes of human insulin-like growth factor-binding protein 2 (hIGFBP-2) with potential immunostimulating and antineoplastic activities. Upon vaccination, pUMVC3-hIGFBP-2 multi-epitope plasmid DNA vaccine may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against hIGFBP-2-expressing cells. The tumor associated antigen (TAA) hIGFBP-2, a member of the insulin like growth factor receptor family, is overexpressed in a number of cancer cell types and its expression has been associated with increased invasiveness." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C95727", "NCT: https://clinicaltrials.gov/ct2/show/NCT01322802", "PubMed:17102977", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5365" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/186" ; obo:OGG_0000000006 "3484" ; obo:VO_0001818 "5365" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: hIGFBP-2" ; rdfs:label "pUMVC3-hIGFBP-2 Multi-Epitope Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007138 obo:IAO_0000115 "A recombinant retrovirus containing the modified murine retroviral vector MFG-S encoding a chimeric construct, MOv18-gamma. MOv18 is a murine monoclonal antibody developed against epitope of human folate binding protein, which is overexpressed on more than 90% of non-mucinous epithelial ovarian neoplasms. The chimeric construct (MOv18-gamma) encodes the variable region of MOv18 antibody, and the gamma chain of human T-cell receptor. This virion might be used to transduce autologous T lymphocytes, and reintroduced back to the patient after expansion ex vivo to invoke specific immune response against ovarian cancer cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29192", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5131" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/356" ; obo:OGG_0000000006 "2348" ; obo:VO_0001818 "5131" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: FOLR1" ; rdfs:label "Retroviral Vector MFGS-MOv18-gamma Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007139 obo:IAO_0000115 "A fowlpox vaccine containing the tumor-associated antigen mucin-1 (MUC1), found in pancreatic tumor cells, and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; TRICOM), which is designed to enhance antigen presentation and activation of immune responses critical for tumor destruction. Vaccination with this agent may elicit a host immune response against MUC1-expressing tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29558", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5477" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/357" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5477" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "rF-MUC1(DF3)/TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007140 obo:IAO_0000115 "A whole cell vaccine comprised of irradiated allogenic pancreatic tumor cells transfected with a plasmid DNA encoding human sargramostim (GM-CSF). Vaccination results in expression of GM-CSF, which induces proliferation and differentiation hematopoietic lineage cells as well as stimulating macrophage and dendritic cell functions in antigen presentation and antitumor cell-mediated immunity. Furthermore, administration of this pancreatic tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2445", "NCT: https://clinicaltrials.gov/ct2/show/NCT00389610", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5340" ; obo:OGG_0000000006 "100137216" ; obo:VO_0001818 "5340" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM-CSF" ; rdfs:label "Sargramostim Plasmid DNA Pancreatic Tumor Cell Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007141 obo:IAO_0000115 "A peptide vaccine containing an HLA-A*2402-restricted epitope of vascular endothelial growth factor receptor 1 (VEGFR1 or Flt-1) with potential immunostimulating, antiangiogenic, and antineoplastic activities. Upon vaccination, VEGFR1-1084 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against VEGFR1-expressing endothelial cells of the tumor microvasculature, which may inhibit tumor angiogenesis and tumor cell proliferation. VEGFR1, a receptor tyrosine kinase, may be overexpressed on endothelial cells of the tumor microvasculature and is associated with tumor cell proliferation, invasion and tumor angiogenesis. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenicity." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C77895", "NCT: https://clinicaltrials.gov/ct2/show/NCT00655785", "PubMed:26190488", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5214" ; obo:OGG_0000000006 "2321" ; obo:VO_0001818 "5214" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: FLT1" ; rdfs:label "VEGFR1-1084 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007142 obo:IAO_0000115 "A peptide vaccine containing an HLA-A*2402-restricted epitope of vascular endothelial growth factor receptor (VEGFR) 2 with potential immunostimulatory and antineoplastic activities. Upon administration, VEGFR2-169 peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against VEGFR2-expressing tumor cells. VEGFR2, a receptor tyrosine kinase, is overexpressed by a variety of tumor types; overexpression is associated with tumor cell proliferation and tumor angiogenesis. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenic peptide immunogenicity." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C74090", "NCT: https://clinicaltrials.gov/ct2/show/NCT00639925", "PubMed:15930316", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5419" ; obo:OGG_0000000006 "16542" ; obo:VO_0001818 "5419" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Kdr" ; rdfs:label "VEGFR2-169 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007143 obo:IAO_0000115 "A cancer vaccine containing HLA class I- and II-binding peptides derived from the NY-ESO-1/LAGE-1 cancer/testis antigen with potential immunostimulatory and antineoplastic activities. Upon administration, NY-ESO-1/LAGE-1 HLA class I/II peptide vaccine may induce a cytotoxic immune response against tumor cells that over-express NY-ESO-1/LAGE-1. Rarely expressed by normal cells, the NY-ESO-1/LAGE-1 cancer/testis antigen has been shown to be preferentially expressed on the surface of some cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C74066", "NCT: https://clinicaltrials.gov/ct2/show/NCT00616291", "PubMed:21131422", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5379" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/111" ; obo:OGG_0000000006 "1485", "30848" ; obo:VO_0001818 "5379" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B|Gene name: CTAG2" ; rdfs:label "NY-ESO-1/LAGE-1 peptide vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007144 obo:IAO_0000115 "An autologous dendritic cell (DCs) vaccine targeting prostate cancer with immunostimulating activity. The autologous DC vaccine is prepared via transfecting DCs with mRNAs extracted from primary prostate cancer tissue, and mRNAs of human telomerase reverse transcriptase (hTERT) and survivin. Upon administration, this DC vaccine may elicit a potent cytotoxic T-cell (CTL) response against prostate cancer cells, resulting in tumor cell death. Both hTERT and survivin are essential in neoplastic growth, and are considered to be universal tumor antigens." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C95771", "NCT: https://clinicaltrials.gov/ct2/show/NCT00345293", "PubMed:30505813", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5205" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5205" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "Primary Prostate Cancer Tissue/hTERT/Survivin mRNA-loaded Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007145 obo:IAO_0000115 "This DNA vaccine expressed prostate-specific membrane antigen (PSMA)" ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "PubMed:22729556", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3710" ; obo:VO_0001818 "3710" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Prostate cancer DNA vaccine pDOM-PSMA27 encoding PSMA" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007146 obo:IAO_0000115 "A cell-based vaccine derived from prostate cancer with potential immunopotentiating and antineoplastic activities. Prostate cancer vaccine ONY-P1 is derived from three irradiated allogeneic prostate cancer cell lines that represent different stages of prostate cancer and express a broad range of prostate and prostate cancer antigens. Upon administration, this vaccine may stimulate a host immune response against prostate cancer cells; in the vaccination schedule, the first two vaccinations are co-administered with bacillus Calmette-Guerin (BCG) as an adjuvant." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C71723", "NCT: https://clinicaltrials.gov/ct2/show/NCT00514072", "PubMed:22932804", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5351" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/141" ; obo:OGG_0000000006 "959" ; obo:VO_0001818 "5351" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD40" ; rdfs:label "Prostate Cancer Vaccine ONY-P1" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007147 obo:IAO_0000115 "A dendritic cell (DC)-based cancer vaccine composed of autologous dendritic cells (DCs) activated with a prostate tumor cell lysate containing tumor-associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, the prostate tumor antigen-activated autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against prostate cancer cells expressing prostate tumor cell-specific antigens, which may result in prostate tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C115106", "NCT: https://clinicaltrials.gov/ct2/show/NCT02111577", "PubMed:27683469", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5132" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5132" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "Prostate Tumor Antigen-activated Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007148 obo:IAO_0000115 "A vaccinia virus carrying a copy of the human gene encoding prostate-specific antigen (PSA), contaminated with bovine viral diarrhea virus (BVDV)." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29334", "PubMed:27683469", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5260" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/142" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5260" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "PROSTVAC-Contaminated W/ BVDV vaccine" ; rdfs:subClassOf obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007149 obo:IAO_0000115 "A peptide vaccine containing the prostate specific antigen (PSA) with potential antineoplastic activity. PSA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed in prostate cancer cells and is used as a tumor marker for both diagnosis and treatment evaluation. Vaccination with PSA peptide vaccine may produce anti-PSA antibodies as well as elicit a cytotoxic T-cell (CTL) response against prostate cancer cells expressing this antigen, thereby decreasing tumor cell growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2497", "NCT: https://clinicaltrials.gov/ct2/show/NCT00015977", "PubMed:27683469", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5087" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/143" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5087" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "PSA Prostate Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007150 obo:IAO_0000115 "An autologous dendritic cell vaccine with potential immunostimulatory activity. Dendritic cells harvested from a prostate cancer patient are transfected with the mRNA encoding for prostate specific antigen (PSA), a tumor marker secreted by prostatic epithelial and ductal cells. When reintroduced back to the patient, these PSA RNA pulsed autologous dendritic cells may elicit a cytotoxic T-cell (CTL) response against PSA-positive prostate cancer cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2236", "NCT: https://clinicaltrials.gov/ct2/show/NCT00004211", "PubMed:14711334", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5022" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/144" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5022" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "PSA RNA-Pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007151 obo:IAO_0000115 "A 30-residue prostate specific antigen (PSA) oligoepitope peptide (OP) vaccine with potential antineoplastic activity. PSA-OP peptide vaccine contains the PSA-1 and PSA-3 HLA-A2 epitopes and the PSA-9 HLA-class I-A3 epitope joined by peptide linker sequences. In an animal model, vaccination with this agent has been shown to elicit a cytotoxic T-lymphocyte immune response." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29337", "PubMed:9743387", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5234" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/179" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5234" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "PSA-OP Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007152 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with the prostate-specific tumor associated antigens (TAAs) prostate specific antigen (PSA) and prostate acid phosphatase (PAP), and conjugated to the immunostimulant keyhole limpet hemocyanin (KLH), with potential immunostimulatory and antineoplastic activities. Upon administration, prostate cancer antigen/KLH-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against prostate cancer cells expressing PSA and PAP, which may result in prostate cancer cell lysis. KLH is an immunogenic carrier and serves as an immunostimulant to improve antigenic immune recognition and T-cell responses and can be used to evaluate vaccine efficacy." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C92573", "NCT: https://clinicaltrials.gov/ct2/show/NCT01171729", "PubMed:12487060", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5353" ; obo:OGG_0000000006 "56318" ; obo:VO_0001818 "5353" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Acpp" ; rdfs:label "PSA-PAP/KLH-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007153 obo:IAO_0000115 "A prostate cancer vaccine containing prostate specific antigen (PSA) combined with the cytokines, interleukin-2 (IL-2) and granulocyte macrophage-colony-stimulating factor (GM-CSF), with potential antineoplastic activity. Upon intradermal vaccination, PSA/IL-2/GM-CSF vaccine may activate the immune system to induce a cytotoxic T-cell (CTL) response against prostate cancer cells expressing this antigen, thereby decreasing tumor cell growth. PSA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed by prostate cancer cells. IL-2 stimulates natural killer (NK) cells and cytotoxic T-cells against the PSA-expressing tumor cells. GM-CSF promotes antigen presentation to dendritic cells and further stimulates a tumor-specific cytotoxic T-lymphocyte (CTL) response." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C114289", "NCT: https://clinicaltrials.gov/ct2/show/NCT02058680", "PubMed:12487060", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5109" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/180" ; obo:OGG_0000000006 "1437", "3558" ; obo:VO_0001818 "5109" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IL-2|Gene name: GM-CSF" ; rdfs:label "PSA/IL-2/GM-CSF Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007154 obo:IAO_0000115 "A plasmid DNA vaccine encoding the tumor-associated antigens (TAAs) prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA), with potential immunoactivating and antineoplastic activities. Upon intramuscular delivery and electroporation of the PSA/PSMA DNA plasmid INO-5150, both PSA and PSMA are translated in cells which then activate the immune system. This induces cytotoxic T-lymphocyte (CTL) responses against tumor cells expressing PSA and PSMA. This may result in both immune-mediated tumor cell death and the inhibition of tumor cell proliferation. PSA and PSMA are overexpressed on a variety of cancer cell types. The DNA encoding the TAAs in INO-5150 is based on both human and other primate antigen gene sequences. As the plasmid genes differ from the human gene sequences encoding these antigens, INO-5150 may overcome immune tolerance to human TAAs." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C123283", "NCT: https://clinicaltrials.gov/ct2/show/NCT02514213", "PubMed:32208168", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5252" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/181" ; obo:OGG_0000000006 "2346" ; obo:VO_0001818 "5252" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: FOLH1" ; rdfs:label "PSA/PSMA DNA Plasmid INO-5150 vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007155 obo:IAO_0000115 "A synthetic peptide based on sequence corresponding to positions 154-163 of the amino acids of prostate-specific antigen (PSA), VISNDVCAQV. Upon administration, PSA:154-163 peptide vaccine may elicit a cytotoxic T-cell response against tumor cells that express PSA." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2798", "NCT: https://clinicaltrials.gov/ct2/show/NCT00004156", "PubMed:19483644", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5106" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/182" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5106" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "PSA:154-163 Peptide vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007156 obo:IAO_0000115 "A cancer vaccine comprised of a synthetic peptide with an amino acid sequence corresponding to positions 154-163 of the amino acid sequence for prostate-specific antigen (PSA) with a leucine substitution at position 155. Upon administration, PSA:154-163(155L) peptide vaccine may elicit a cytotoxic T-cell response against tumor cells that express PSA." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29338", "NCT: https://clinicaltrials.gov/ct2/show/NCT00109811", "PubMed:19483644", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5155" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/183" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5155" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "PSA:154-163(155L) Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007157 obo:IAO_0000115 "A peptide-based cancer vaccine containing epitopes of T cell receptor gamma-chain alternate reading frame protein (TARP) and prostate-specific membrane antigen (PSMA) in combination with a Poly IC-LC immunoadjuvant, with potential antineoplastic activity. Upon administration, PSMA/TARP peptide vaccine may stimulate a host cytotoxic T-cell (CTL) response against TARP- and PSMA-expressing tumor cells, resulting in tumor cell cytotoxicity. The nuclear protein TARP and PSMA are commonly expressed in prostate cancer cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C78819", "NCT: https://clinicaltrials.gov/ct2/show/NCT00694551", "PubMed:34494382", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5052" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/184" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5052" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "PSMA/TARP Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007158 obo:IAO_0000115 "A cancer vaccine containing plasmid DNA encoding human prostatic acid phosphatase (PAP) (pTVG-HP) with potential immunostimulatory and antineoplastic activities. Upon administration, pTVG-HP plasmid DNA vaccine may stimulate the host immune system to generate a cytotoxic T lymphocyte (CTL) response against PAP-expressing prostate cancer cells. PAP or prostatic specific acid phosphatase (PSAP) is a tumor associated antigen (TAA) that may be overexpressed in prostate cancer." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C82407", "NCT: https://clinicaltrials.gov/ct2/show/NCT02499835", "PubMed:17102977", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5535" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/185" ; obo:OGG_0000000006 "55" ; obo:VO_0001818 "5535" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ACP3" ; rdfs:label "pTVG-HP Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007159 obo:IAO_0000115 "A cancer√ävaccine√äcontaining xenogenic√äDNA√äfrom rhesus macaque (Macaca mulatta) that encodes prostate specific antigen (PSA) with potential immunostimulating and antineoplastic activities. Upon repeated intradermal administration via electroporation,√äpVAXrcPSAv53l√ävaccine√ämay induce a cytotoxic T-lymphocyte (CTL) response against PSA-expressing prostate cancer cells. Rhesus PSA is 89% homologous to human PSA." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C82352", "NCT: https://clinicaltrials.gov/ct2/show/NCT00859729", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5092" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/187" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5092" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "pVAXrcPSAv53l DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007160 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA). Administration of this agent may stimulate a cytotoxic T cell response against PSA-expressing tumor cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2675", "NCT: https://clinicaltrials.gov/ct2/show/NCT00005039", "PubMed:17707059", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4988" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/333" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "4988" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "Recombinant Fowlpox-Prostate Specific Antigen Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007161 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant fowlpox virus encoding fragment of human prostate-specific antigen (PSA), PSA:154-163 (155L), and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). Administration of this agent may induce a cytotoxic T cell response against PSA-expressing tumor cells. Dendritic cells infected with TRICOM vectors greatly enhance naive T-cell activation and peptide-specific T-cell stimulation. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C38708", "NCT: https://clinicaltrials.gov/ct2/show/NCT00108732", "PubMed:16390546", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5434" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/333" ; obo:OGG_0000000006 "12519", "3383", "354", "965" ; obo:VO_0001818 "5434" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3|Gene name: Cd80|Gene name: ICAM1|Gene name: CD58" ; rdfs:label "Recombinant Fowlpox-PSA(L155)/TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007162 obo:IAO_0000115 "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding TRICOM. TRICOM is comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3) that may enhance antigen presentation and activate cytotoxic T-cells. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2667", "NCT: https://clinicaltrials.gov/ct2/show/NCT00450619", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5253" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/132" ; obo:OGG_0000000006 "12519", "3383", "965" ; obo:VO_0001818 "5253" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Cd80|Gene name: ICAM1|Gene name: CD58" ; rdfs:label "Recombinant Fowlpox-TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007163 obo:IAO_0000115 "A vaccine consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA). Vaccination with recombinant vaccinia prostate-specific antigen vaccine stimulates the host immune system to mount a cytotoxic T-cell response against tumor cells expressing PSA." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2433", "NCT: https://clinicaltrials.gov/ct2/show/NCT02649439", "PubMed:12242725", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5154" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/339" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5154" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "Recombinant Vaccinia PSA Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007164 obo:IAO_0000115 "A recombinant vaccinia virus encoding prostate-specific antigen (PSA). Vaccination with recombinant vaccinia-PSA may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for PSA, which may decrease tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29945", "NCT: https://clinicaltrials.gov/ct2/show/NCT00005039", "PubMed:12242725", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5302" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/350" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5302" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "Recombinant Vaccinia-Prostate Specific Antigen Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007165 obo:IAO_0000115 "A recombinant vaccinia virus encoding prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) with potential use in cancer immunotherapy." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29563", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5307" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/351" ; obo:OGG_0000000006 "2346", "354" ; obo:VO_0001818 "5307" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3|Gene name: Prostate-specific membrane antigen" ; rdfs:label "Recombinant Vaccinia-PSA/PSMA Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007166 obo:IAO_0000115 "A synthetic fowlpox viral vaccine containing the tumor-associated antigens prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; TRICOM). Vaccination with this viral vaccine may enhance antigen presentation and activate cytotoxic T-cells against PSA- or PSMA-expressing tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29559", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5005" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/358" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5005" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "rF-PSA/PSMA/TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007167 obo:IAO_0000115 "A vaccine formulation consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA) and recombinant vaccinia virus encoding three co-stimulatory molecule transgenes B7.1, ICAM-1, and LFA-3 (TRICOM). Vaccination with PSA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells expressing PSA." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38681", "NCT: https://clinicaltrials.gov/ct2/show/NCT02772562", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5183" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/359" ; obo:OGG_0000000006 "12519", "3383", "354", "965" ; obo:VO_0001818 "5183" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ICAM1|Gene name: Cd80|Gene name: KLK3|Gene name: CD58" ; rdfs:label "Rilimogene-galvacirepvec Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007168 obo:IAO_0000115 "A cell-based vaccine composed of autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C1985", "NCT: https://clinicaltrials.gov/ct2/show/NCT02159950", "PubMed:20818862", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5216" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/362" ; obo:OGG_0000000006 "55" ; obo:VO_0001818 "5216" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ACP3" ; rdfs:label "Sipuleucel-T Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007169 obo:IAO_0000115 "A synthetic peptide vaccine, containing 16 amino acid residues (611-626) of the human telomerase reverse transcriptase catalytic subunit (hTERT), with potential antineoplastic activity. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation. Vaccination with tertomotide may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against telomerase-expressing cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C62756", "NCT: https://clinicaltrials.gov/ct2/show/NCT02855892", "PubMed:27941629", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5101" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/416" ; obo:OGG_0000000006 "22059" ; obo:VO_0001818 "5101" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Trp53" ; rdfs:label "Telomerase Peptide Vaccine GV1001" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007170 obo:IAO_0000115 "A synthetic, peptide cancer vaccine directed against the human telomerase reverse transcriptase catalytic subunit (hTERT) with potential immunomodulating activity. Vaccination with the UV1 telomerase peptide may stimulate cytotoxic T-cells to recognize and kill telomerase-expressing cells. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01784913", "PubMed:28391357", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5478" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5478" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "UV1 Telomerase Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007171 obo:IAO_0000115 "An adenovirus type 5 (Ad5) encoding human tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), with potential apoptosis-inducing and antineoplastic activities. Upon administration of recombinant Ad5 encoding TRAIL, the adenovirus selectively infects tumor cells and expresses TRAIL. The virally expressed TRAIL binds to and activates its receptors TRAIL receptor-1 (TRAIL-R1, death receptor 4, DR4) and TRAIL receptor-2 (TRAIL-R2, death receptor 5, DR5), which subsequently activate caspases and induce apoptosis in TRAIL-R1/R2-expressing tumor cells. The pro-apoptotic cell surface receptors TRAIL-R1 and -R2, members of the TNF receptor family, are overexpressed by a variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C116879", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5397" ; obo:OGG_0000000006 "8743" ; obo:VO_0001818 "5397" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TNFSF10" ; rdfs:label "Recombinant Adenovirus 5 Encoding Tumor Necrosis Factor-related Apoptosis-Inducing Ligand Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007172 obo:IAO_0000115 "A multipeptide cancer vaccine targeting renal cell carcinoma with potential immunopotentiating activity. Renal cell carcinoma peptides vaccine IMA901 consists of 10 different synthetic tumor-associated peptide (TUMAP) antigens (9 HLA-class I-binding and 1 HLA class II-binding); endogenously, these TUMAPs are expressed by the majority of renal cell carcinomas. Vaccination with this agent may significantly increase host cytotoxic T-lymphocyte (CTL) immune responses against tumor cells expressing these peptide antigens." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C70968", "NCT: https://clinicaltrials.gov/ct2/show/NCT00523159", "PubMed:23899354", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5013" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/354" ; obo:OGG_0000000006 "3105", "3106" ; obo:VO_0001818 "5013" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HLA-A|Gene name: HLA-B" ; rdfs:label "Renal Cell Carcinoma Peptides Vaccine IMA901" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007173 obo:IAO_0000115 "A cell-based preparation in which autologous, mature dendritic cells (DCs) are electroporated with in vitro transcribed (IVT) RNAs encoding for a synthetic form of T-cell protein CD40 ligand (CD40L) and IVT RNA encoding for autologous tumor-associated antigens (TAAs) derived from patient-specific bladder cell carcinoma (BCC) cells, with potential immunostimulatory and antineoplastic activities. Upon electroporation into autologous DCs, the RNA is translated and processed. BCC-specific antigenic peptides are subsequently presented via major histocompatibility complex (MHC) Class I molecules on the DCs surface. When AGS-003-BLD is reintroduced to the patient, the MHC-presented peptides interact with and activate CD8-positive T cells, which elicits a highly specific cytotoxic T-cell (CTL) response against tumor cells expressing the patient-specific BCC TAAs. The signal cascade initiated by expression of the co-stimulatory molecule CD40L results in the secretion of the inflammatory cytokine IL-12, which further stimulates CTLs." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C129522", "NCT: https://clinicaltrials.gov/ct2/show/NCT02170389", "PubMed:25901286", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5373" ; obo:OGG_0000000006 "958" ; obo:VO_0001818 "5373" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD40" ; rdfs:label "Renal Cell Carcinoma/CD40L RNA-Transfected Autologous Dendritic Cell Vaccine AGS-003" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007174 obo:IAO_0000115 "Peripheral blood lymphocytes (PBL) harvested from the blood of a renal cancer patient and exposed in vitro to renal tumor-associated antigens (TAA). Introducing these renal tumor-reactive autologous peripheral blood lymphocytes back to the same patient target tumor cells expressing these TAAs and could induce a cytotoxic T-cell-mediated immune response against renal cell cancer." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C48816", "PubMed:33408117", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5196" ; obo:VO_0001818 "5196" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Renal Tumor-Reactive Autologous Peripheral Blood Lymphocyte Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007175 obo:IAO_0000115 "A peptide vaccine consisting of amino acids 65 through 76 derived from the tumor suppressor protein Von Hippel-Lindau (VHL) with a glycine substitution at position 74. As a cancer vaccine, VHL-59: 65-76(V74G) may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38122", "PubMed:20109232", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5097" ; obo:OGG_0000000006 "7428" ; obo:VO_0001818 "5097" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VHL" ; rdfs:label "VHL-42: 65-76(V74G) Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007176 obo:IAO_0000115 "A peptide vaccine consisting of amino acids 116 through 128 derived from the tumor suppressor protein Von Hippel-Lindau (VHL) with a frameshift mutation. As a cancer vaccine, VHL-59: 116-128(FrSh116-128) peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38123", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5172" ; obo:OGG_0000000006 "7428" ; obo:VO_0001818 "5172" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VHL" ; rdfs:label "VHL-59: 116-128 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007177 obo:IAO_0000115 "A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL14 peptide is a point mutation variant of the VHL protein; the mutation is in amino acid position 166. It might be used to elicit or boost cellular immunity to cancers that expressing the von Hippel-Lindau mutation." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2741", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5012" ; obo:OGG_0000000006 "7428" ; obo:VO_0001818 "5012" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VHL" ; rdfs:label "VHL14 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007178 obo:IAO_0000115 "A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL16 peptide, also known as S111I, is a point mutation variant of the VHL tumor suppressor protein; the mutation is in amino acid position 111. Vaccination with this agent may stimulate a cytotoxic T-cell response in patients with VHL-associated cancers that express this variant of the VHL tumor suppressor protein." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2740", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5333" ; obo:OGG_0000000006 "7428" ; obo:VO_0001818 "5333" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VHL" ; rdfs:label "VHL16 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007179 obo:IAO_0000115 "A peptide vaccine derived from the von Hippel-Lindau (VHL) tumor suppressor protein, a general transcription factor. VHL2 (Y12M) peptide is a point mutation variant (from tyrosine to methionine at amino acid position 12) of the VHL protein. Vaccination with this peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2824", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5490" ; obo:OGG_0000000006 "7428" ; obo:VO_0001818 "5490" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VHL" ; rdfs:label "VHL2 (Y12M) Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007180 obo:IAO_0000115 "A cancer vaccine composed of peptides derived from a tumor-associated protein encoded by a mutated Von Hippel-Lindau (VHL) oncogene. VHL peptide vaccine may stimulate a cytotoxic T cell response against tumor cells expressing the VHL tumor-associated protein." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2492", "NCT: https://clinicaltrials.gov/ct2/show/NCT00001703", "PubMed:20109232", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5127" ; obo:OGG_0000000006 "7428" ; obo:VO_0001818 "5127" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VHL" ; rdfs:label "Von Hippel-Lindau Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007181 obo:IAO_0000115 "A synthetic peptide vaccine based on the sequences of a translocation mutation of 2 transcriptional factor genes, PAX3 and FKHR. PAX3/FKHR fusion proteins are frequently found in patients with rhabdomyosarcomas. Vaccination with PAX3/FKHR peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this PAX3/FKHR fusion protein." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C49023", "NCT: https://clinicaltrials.gov/ct2/show/NCT00001564", "PubMed:15838707", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5484" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/114" ; obo:OGG_0000000006 "2308", "5077", "7422" ; obo:VO_0001818 "5484" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PAX3|Gene name: FOXO1|Gene name: VEGFA" ; rdfs:label "PAX3/FKHR Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007182 obo:IAO_0000115 "A recombinant retroviral virus derived from SR-A strain of Rous sarcoma virus carrying a constitutively active form of the√äAKT√äGene. The viral vector√äRCAS√äharbors a Replication Competent ALV Splice acceptor. This recombinant virus was use in animal model to study gliomagenesis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29908", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5044" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/192" ; obo:OGG_0000000006 "207" ; obo:VO_0001818 "5044" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: AKT1" ; rdfs:label "RCAS-Akt Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007183 obo:IAO_0000115 "A recombinant retroviral virus derived from SR-A strain of Rous sarcoma virus carrying a human gene encoding the G12D mutant form of K-Ras. The viral vector,√äRCAS√äharbors a Replication Competent ALV Splice acceptor. This recombinant virus was use in animal model to study gliomagenesis." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29910", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5500" ; obo:OGG_0000000006 "3845" ; obo:VO_0001818 "5500" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KRAS" ; rdfs:label "RCAS-Ras Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007184 obo:IAO_0000115 "A recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT). Telomerase expression has been directly linked to tumor development; its catalytic subunit is expressed in the majority of human cancer cells, but infrequently in normal cells. Vaccination with telomerase:540-548 peptide may stimulate cytotoxic T cells to recognize and kill telomerase-expressing cells." ; obo:IAO_0000117 "Jie Zheng", "Jimmy Guo", "Oliver He", "Virginia He" ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C2640", "NCT: https://clinicaltrials.gov/ct2/show/NCT00069940", "PubMed:11536162", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5098" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5098" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "Telomerase: 540-548 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007186 obo:IAO_0000115 "To obtain SOCS1-silenced DCs, DCs derived from mouse bone marrow cells ex vivo were induced to differentiation in the presence of granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-4, and then transduced with Len-SOCS1-shRNA or control Len-GFP lentiviruses. The SOCS1-silenced DCs were loaded by TRP2 peptide to prepare the DC vaccine, which was induced to mature by LPS. The DCs were analyzed by flow cytometry (FCM) for surface expressions of MHCII and CD86 and by real-time PCR for the expressions of SOCS1, IL-10 as well as IL-12p40. B16 or IL-10-silenced B16 (IL-10(-/-);) cells were inoculated into C57BL/6 mice." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:23643168", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4071" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/78" ; obo:VO_0001818 "4071" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "1(SOCS1)-silenced dendritic cell (DC) Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0007187 obo:IAO_0000115 "A fragment of fibroblast growth factor-5 (FGF-5). Originally isolated from a renal cell carcinoma cell line that overexpressed FGF-5, FGF-5:117-126 peptide is recognized by tumor infiltrating cytotoxic T lymphocytes. Overexpressed by several cancer cell types, this peptide is being tested as a potential target for antineoplastic immunotherapies. (NCI04)" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5414" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/79" ; obo:VO_0001818 "5414" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "117-126:FGF-5 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007188 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5418" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/80" ; obo:VO_0001818 "5418" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "12 Melanoma Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007189 obo:IAO_0000115 "2 class major histocompatibility complex√êrestricted melanoma peptides" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:21690475", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3978" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/81" ; obo:VO_0001818 "3978" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "12MP Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007190 obo:IAO_0000115 "4 treatment groups, vaccinated with 12 MHC class I-restricted melanoma peptides to stimulate CTL (12 MP, group A), plus a tetanus peptide (group B), or a mixture of 6 melanoma helper peptides (6 MHP, group C) to stimulate helper T lymphocytes (HTL), or with 6 melanoma helper peptide (6 MHP) alone (group D), in incomplete Freund's adjuvant plus granulocyte macrophage colony-stimulating factor." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:23653149", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4070" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/82" ; obo:VO_0001818 "4070" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "12MP, 12MP/Tet, 12MP/6MHP, or 6MHP Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ] . obo:VO_0007191 obo:IAO_0000115 "A synthetic peptide consisting of amino acids 27 through 35 of the melanoma differentiation antigen MART-1. 27-35(27L) MART-1 has a leucine substitution at amino acid position 27 to improve binding to HLA-A*0201. Vaccination with this agent may stimulate the host immune response to mount a cytotoxic T-lymphocyte response against melanoma cells expressing MART-1." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:22495394", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5290" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/83" ; obo:OGG_0000000006 "2315", "6490", "7299" ; obo:VO_0001818 "5290" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase|Gene name: gp100|Gene name: MLANA" ; rdfs:label "27-35(27L):MART-1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007192 obo:IAO_0000115 "A topical gel containing a peptide derived from the human papillomavirus (HPV). Application of 851B gel may stimulate the host immune system to trigger a cytotoxic T-lymphocyte response to cells that express HPV." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4986" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/84" ; obo:VO_0001818 "4986" ; a owl:Class ; rdfs:label "851B Gel Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ] . obo:VO_0007193 obo:IAO_0000115 "A murine IgG1 monoclonal anti-idiotype antibody, containing a variable antigen-binding region that functionally mimics the three-dimensional structure of a specific epitope on the ovarian cancer tumor-associated antigen CA-125, with potential antineoplastic activity. With a variable antigen-binding region that acts as a surrogate antigen for CA-125, abagovomab may stimulate the host immune system to elicit humoral and cellular immune responses against CA-125-positive tumor cells, resulting in inhibition of tumor cell proliferation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:17000686", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5244" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/86" ; obo:OGG_0000000006 "94025" ; obo:VO_0001818 "5244" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC16" ; rdfs:label "Abagovomab" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007194 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:11860704", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5543" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/87" ; obo:OGG_0000000006 "2875", "7124" ; obo:VO_0001818 "5543" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: TNF|Gene name: GPT" ; rdfs:label "Ad CMV I kappaB alpha Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007195 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant adenoviral vector encoding the tumor-associated antigen (TAA) human MUC-1 (hMUC-1) linked to the extracellular domain (ecd) of the co-stimulatory molecule CD40 ligand (CD40L) and an adenovirus signal sequence that encodes a secretory signal peptide (Ad-sig) with potential immunostimulating and antineoplastic activities. Due to the presence of the secretory signal peptide expressed by Ad-sig in the vaccine construct, transfected cells may secrete a fusion protein composed of hMUC-1 and the CD40L ecd. The CD40L moiety part of the fusion protein binds to CD40 receptors on dendritic cells (DCs). Subsequently, DCs may be activated and migrate, T-cells may expand, and a cytotoxic T lymphocyte (CTL) response against tumor cells that overexpress hMUC-1 may follow. MUC-1 is a hypoglycosylated TAA overexpressed by epithelial cancer cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5179", "https://ascopubs.org/doi/10.1200/JCO.2018.36.15_suppl.3098" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/88" ; obo:OGG_0000000006 "4582", "959" ; obo:VO_0001818 "5179" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1|Gene name: CD40LG" ; rdfs:label "Ad-sig-hMUC-1/ecdCD40L Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, obo:VO_0005484, obo:VO_0005486, obo:VO_0005489, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007196 obo:IAO_0000115 "A replication-competent oncolytic adenovirus encoding the murine pro-inflammatory cytokine interleukin-12 (IL-12) gene and two suicide fusion genes, a yeast cytosine deaminase (yCD) and a mutant form of herpes simplex virus type 1 thymidine kinase (HSV-1 TKSR39), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration of Ad5-yCD/mutTKSR39rep-hIL12, the adenovirus selectively infects and replicates in tumor cells, which results in direct tumor cell lysis. Synergistically, IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells (NKs), inducing secretion of interferon-gamma (IFN-g) and inducing cytotoxic T-lymphocyte (CTL) responses against tumor cells, which may result in immune-mediated tumor cell death, inhibition of tumor cell proliferation and inhibition of tumor angiogenesis. In addition, Ad5-yCD/mutTKSR39rep-hIL12-infected cancer cells express yCD and TKSR39; upon administration of the prodrugs 5-fluorocytosine (5-FC) and valganciclovir (vGCV), the yCD and HSV-1 TKSR39 activate these prodrugs to form 5-fluorouracil (5-FU) and ganciclovir, respectively. 5-FU gets converted to 5-fluoro-uridine monophosphate (5-FUMP) and subsequently to 5-fluoro-deoxyuridine monophosphate (5-FdUMP); 5-FdUMP irreversible inhibits thymidylate synthase, inhibits deoxythymidine triphosphate (dTTP) formation and halts DNA synthesis. Once phosphorylated intracellularly, ganciclovir triphosphate competitively inhibits deoxyguanosine triphosphate (dGTP) incorporation into DNA and inhibits DNA synthesis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5308", "https://www.cell.com/molecular-therapy-family/oncolytics/pdf/S2372-7705(20)30171-6.pdf, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281656/" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/89" ; obo:OGG_0000000006 "3592", "3593" ; obo:VO_0001818 "5308" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IL12B|Gene name: IL12A" ; rdfs:label "Ad5-yCD/mutTKSR39rep-hIL12 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005486, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5409 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_769 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007197 obo:IAO_0000115 "A nonreplicating adenoviral vector (adenovector) encoding the melanoma differentiation-associated 7 gene (MDA7) with potential antineoplastic activity. After intratumoral injection and adenovector-mediated gene transfer of MDA7 into tumor cells, the expressed MDA7 transgene may inhibit tumor cell proliferation and induce tumor cell apoptosis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15300212", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5523" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/92" ; obo:VO_0001818 "5523" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Adenovector Encoding MDA7 Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007198 obo:IAO_0000115 "A genetically-modified, dendritic cell-based (DCs) vaccine in which the autologous cells are transduced with an adenoviral vector expressing the tumor antigen prostate-specific membrane antigen (PSMA) and a fusion protein composed of synthetic ligand inducible adjuvant iMC composed of a drug-inducible costimulatory CD40 receptor (iCD40) and the adaptor protein MyD88, with potential immunomodulating and antineoplastic activities. The iCD40 contains a membrane-localized cytoplasmic CD40 domain fused to the FK506 modified drug-binding protein 12 (FKBP12). Upon intradermal administration of BPX-201, these DCs accumulate in local draining lymph nodes. Twenty-four hours after vaccination, the dimerizing agent AP1903 is administered. AP1903 binds to the drug binding domain, leading to iMC oligomerization and activation of iCD40 and MyD88-mediated signaling in iMC-expressing DCs. This signaling pathway activates the DCs and stimulates a cytotoxic T-lymphocyte (CTL) response against host tumor cells that express PSMA. PSMA, a glycoprotein secreted by prostatic epithelial and ductal cells, is overexpressed in prostate cancer cells and is used as a tumor marker for both diagnosis and treatment evaluation. MyD88 is involved in interleukin 1 receptor (IL1R) and toll-like receptor (TLR) signaling." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4999" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/93" ; obo:OGG_0000000006 "2346" ; obo:VO_0001818 "4999" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Prostate-specific membrane antigen" ; rdfs:label "Adenovector-transduced AP1903-inducible MyD88/CD40-expressing Autologous PSMA-specific Prostate Cancer Vaccine BPX-201" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007199 obo:IAO_0000115 "A replication-defective, E1- and E2b-deleted oncolytic adenoviral serotype 5 (Ad5) encoding an epitope of human carcinoembryonic antigen (CEA) with potential antineoplastic activity. Adenoviral vector Ad5-CEA(6D) vaccine expresses a highly immunogenic analogue of CEA [CAP1-(6D)]. Upon administration, this vaccine may induce both humoral and cellular immune responses against tumor cells expressing the CEA antigen, thereby resulting in the immune-mediated inhibition of tumor cell proliferation and tumor cell death. CEA, a tumor-associated antigen, is overexpressed in various tumor cell types. Deletion of early genes E1 and E2b in Ad5 potentially circumvent pre-existing anti-adenovirus immunity and is capable of inducing strong immune responses." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:25956394", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5137" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/94" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5137" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5" ; rdfs:label "Adenoviral Vector Ad5-CEA(6D) Vaccine" ; rdfs:subClassOf obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007200 obo:IAO_0000115 "An adenovirus vector engineered to produce CD40 ligand. For use as a possible gene therapy agent. May induce apoptosis through the TNF pathway." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15153545", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5529" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/95" ; obo:VO_0001818 "5529" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Adenovirus 5-CD40 Ligand Vaccine" ; rdfs:subClassOf obo:VO_0005485, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0007201 obo:IAO_0000115 "Fibroblast growth factor-2-retargeted adenoviral vectors may be used to increase the transduction of GBM-derived endothelial cells, enabling a new and efficient antiangiogenesis strategy for the treatment of malignant gliomas." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:16709032", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5489" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/96" ; obo:OGG_0000000006 "2247" ; obo:VO_0001818 "5489" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: FGF2" ; rdfs:label "Adenovirus 5-Fibroblast Growth Factor 2 Vaccine" ; rdfs:subClassOf obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ] . obo:VO_0007202 obo:IAO_0000115 "A replication-defective, recombinant adenoviral serotype 5 (Ad5) encoding human guanylyl cyclase C (hGCC) and the synthetic Pan DR epitope (PADRE), with potential antineoplastic and immunomodulating activities. Upon intramuscular administration, the Ad5-hGCC-PADRE vaccine expresses hGCC, which may induce both humoral and cellular immune responses against tumor cells expressing the hGCC antigen. This results in the immune-mediated inhibition of tumor cell proliferation, and leads to tumor death. The hGCC protein is normally restricted to intestinal epithelial cells but is overexpressed by metastatic colorectal tumors. PADRE is a helper T-lymphocyte epitope that is able to augment the magnitude and duration of the cytotoxic T-lymphocyte (CTL) response." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT04111172", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5147" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/97" ; obo:OGG_0000000006 "2984" ; obo:VO_0001818 "5147" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GUCY2C" ; rdfs:label "Adenovirus 5-Human Guanylyl Cyclase C-PADRE Vaccine" ; rdfs:subClassOf obo:VO_0005490, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3717 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007203 obo:IAO_0000115 "A gene-viral vector complex comprised of an adenovirus vector and B7-1 gene targeting the CD80 antigen. Adenovirus B7-1 is used as a component in antineoplastic vaccines to elicit a cytotoxic T-cell response." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5435" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/98" ; obo:OGG_0000000006 "941" ; obo:VO_0001818 "5435" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: CD80" ; rdfs:label "Adenovirus B7-1 Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0007204 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant adenoviral vector encoding HER-2/neu." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00307229", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5388" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/99" ; obo:OGG_0000000006 "24337" ; obo:VO_0001818 "5388" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Erbb2" ; rdfs:label "Adenovirus Encoding Rat HER-2/neu Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007205 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a recombinant adenoviral vector encoding three full length human melanoma associated antigens (MAAs), tyrosinase, melan-A (MART-1) and the melanoma antigen A6 (MAGEA6), with potential antineoplastic activity. Upon intradermal administration, adenovirus encoding tyrosinase/MART-1/MAGEA6-transduced autologous DC vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tyrosinase/MART-1/MAGEA6-positive tumor cells, which may result in tumor cell death and decreased tumor growth. Tyrosinase, a melanoma-specific differentiation antigen, catalyzes the first step of melanin synthesis in melanocytes. Vaccination with multi-antigen modified DC may improve the efficacy of the DC immunotherapy." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:22737604", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5370" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/100" ; obo:OGG_0000000006 "2315", "4105", "7299" ; obo:VO_0001818 "5370" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase|Gene name: MLANA|Gene name: MAGEA6" ; rdfs:label "Adenovirus Encoding Tyrosinase/MART-1/MAGEA6-transduced Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007206 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) transduced with a replication-deficient adenovirus vector encoding HER-2 with potential antineoplastic activity. Upon administration, adenovirus HER2-transduced autologous dendritic cell vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against HER-2-positive tumor cells, which may result in tumor cell death and decreased tumor growth. HER-2, a tyrosine kinase receptor for epidermal growth factor (EGF) (also known as neu and ErbB2), is overexpressed by some breast, ovarian, and gastric cancers." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00197522", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5082" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/101" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5082" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Adenovirus HER2-Transduced Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007207 obo:IAO_0000115 "A gene viral vector complex comprised of a replication-defective adenovirus and a herpes simplex virus thymidine kinase gene that activates ganciclovir, causing inhibition of DNA synthesis and apoptosis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:/8985364", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5122" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/102" ; obo:VO_0001818 "5122" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Adenovirus RSV-TK Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007208 obo:IAO_0000115 "A replication incompetent adenovirus encoding human pro-inflammatory cytokine interleukin-12 (IL-12) (Ad.hIL-12), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration, the adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis. Synergistically, IL-12 expressed by the adenovirus may activate the immune system by promoting the activation of natural killer cells (NKs), inducing secretion of interferon-gamma and inducing cytotoxic T cell responses against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:33575474", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5285" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/103" ; obo:OGG_0000000006 "2346" ; obo:VO_0001818 "5285" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Prostate-specific membrane antigen gene engineering" ; rdfs:label "Adenovirus-mediated Human Interleukin-12 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007209 obo:IAO_0000115 "A cancer vaccine consisting of autologous dendritic cells (DCs) transduced with a recombinant adenovirus encoding p53 peptide, with potential immunomodulating activity. Intradermal vaccination with adenoviral-p53 transduced dendritic cell vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. p53, a tumor suppressor gene, is mutated in many tumor cells, resulting in the loss of apoptosis regulation and abnormal cell proliferation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:20420527", "PubMed:29515795", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5256" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/104" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "5256" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53 (P53)" ; rdfs:label "Adenovirus-p53 Transduced Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007210 obo:IAO_0000115 "A cancer vaccine composed of a genetically engineered, replication-deficient type 5 adenovirus carrying the human prostate-specific antigen (PSA), with potential immunostimulating and antineoplastic activities. Upon subcutaneous vaccination with the adenovirus-PSA prostate cancer vaccine, the adenovirus infects cells and expresses PSA. In turn, PSA may activate the immune system and may induce a cytotoxic T-lymphocyte response against PSA-expressing tumor cells. PSA, a tumor associated antigen, is expressed by prostate epithelial cells and is overexpressed in prostate cancer." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5010" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/105" ; obo:OGG_0000000006 "2346" ; obo:VO_0001818 "5010" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Prostate-specific membrane antigen gene engineering" ; rdfs:label "Adenovirus-PSA Prostate Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007211 obo:IAO_0000115 "A cell-based vaccine comprised of prostate cancer cells transduced with an adenoviral vector encoding human RTVP-1 (AdRTVP-1), with potential antineoplastic and immunostimulating activities. RTVP-1, also referred to as glioma pathogenesis-related protein 1 (GLIP1), is down-regulated in prostate tumors. Regulated by tumor suppressor p53, the expression of RTVP-1 functions as a tumor suppressor, and is abundant in normal human prostate epithelial cells as well as in differentiated macrophages. Administration of this vaccine leads to an induction of apoptosis through the expression of RTVP-1 and results in a reduction in cellular proliferation in prostate cancer cells. In addition, this cancer-cell based vaccine may induce a cytotoxic T lymphocyte (CTL) response against prostate specific tumor associated antigens, resulting in an immune-mediated prostate cancer cell death. Furthermore, RTVP-1 stimulates CTL and natural killer (NK) cell activities." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5203" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/106" ; obo:OGG_0000000006 "11010" ; obo:VO_0001818 "5203" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GLIPR1" ; rdfs:label "AdRTVP-1-Transduced Prostate Cancer Cell-Based Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007212 obo:IAO_0000115 "A vaccine containing HER2/Neu-derived epitope (amino acids 776-790) linked to li-Key peptide (li-Key/HER2/neu hybrid peptide or AE37), and combined with granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential antineoplastic and immunoadjuvant activities. Upon vaccination, AE37 may activate the immune system and stimulate T-helper cells against HER2/Neu expressing cancer cells. GM-CSF may potentiate the immune response against cancer cells expressing the HER2/Neu antigen. The Ii-Key moiety, a 4-amino acid (LRMK) epitope from the MHC class II-associated invariant chain (Ii protein), increases T-helper cell stimulation against HER2/neu antigen when compared to unmodified class II epitopes. HER2/neu, a tumor associated antigen (TAA), is overexpressed in a variety of tumor cell types and is highly immunogenic." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:32323103", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5436" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/107" ; obo:OGG_0000000006 "1437", "2064" ; obo:VO_0001818 "5436" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM-CSF|Gene name: ERBB2" ; rdfs:label "AE37 Peptide/GM-CSF Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007213 obo:IAO_0000115 "A cancer vaccine composed of naked plasmid DNA of the gene for the tumor-associated antigen alpha-fetoprotein (AFP), a macromolecule that acts as a specific immunologic target for hepatocellular carcinoma. This agent exerts an antitumor effect by inducing cytotoxic T-lymphocytes to attack AFP-expressing tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5275" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/108" ; obo:OGG_0000000006 "174" ; obo:VO_0001818 "5275" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: AFP" ; rdfs:label "AFP Gene Hepatocellular Carcinoma Vaccine" ; rdfs:subClassOf obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007214 obo:IAO_0000115 "A cancer vaccine made of a recombinant NY-ESO-1 protein with a TLR7 agonist" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:C5941317", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3991" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/109" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "3991" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "Ag NY-ESO-1 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007215 obo:IAO_0000115 "A cancer vaccine containing the three frame shift peptides (FSP) AIM2(-1), HT001(-1) and TAF1B(-1), with potential immunomodulating activity. Upon administration, the AIM2(-1)/HT001(-1)/TAF1B(-1) FSP vaccine may induce an immune response against microsatellite instability (MSI) colorectal cancer-associated antigens. Frame shift mutations of AIM2 (absent in melanoma 2, an interferon-inducible protein), HT001 (asteroid homolog 1 or ASTE1, with an unknown function) and TAF1B (TATA box-binding protein-associated RNA polymerase I B, a transcription factor) are seen in MSI-positive colorectal cancers and may be associated with malignant transformation, tumor progression and the presence of tumor-infiltrating lymphocytes. These FSPs all have one-base deletions." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01461148", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5402" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/110" ; obo:OGG_0000000006 "28990", "9014", "9447" ; obo:VO_0001818 "5402" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: AIM2|Gene name: TAF1B|Gene name: ASTE1" ; rdfs:label "AIM2(-1)/HT001(-1)/TAF1B(-1) Frameshift Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007216 obo:IAO_0000115 "A cancer vaccine comprised of irradiated allogeneic pancreatic cancer cells transfected to express murine alpha-1,3-galactosyltransferase with potential antitumor activity. Vaccination is associated with the expression of murine alpha-1,3-galactosyl (alpha-gal) carbohydrate residues on cell membrane glycoproteins and glycolipids of the vaccine pancreatic cancer cell allograft; murine alpha-gal epitopes, not present on human cells, then induce a hyperacute rejection of the vaccine pancreatic cancer cell allograft. The hyperacute rejection involves the binding of pre-existing human anti-alpha-gal antibodies (which naturally occur against gut flora) to murine alpha-gal epitopes, resulting in the rapid activation of antibody-dependent cell-mediated cytotoxicity (ADCC) towards allograft cells. The host immune system then attacks endogenous pancreatic cancer cells, resulting in ADCC towards endogenous pancreatic cancer cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:26787078", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5422" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/145" ; obo:OGG_0000000006 "1048", "111518" ; obo:VO_0001818 "5422" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5|CEA" ; rdfs:label "Algenpantucel-L Vaccine" ; rdfs:subClassOf obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007217 obo:IAO_0000115 "A cancer vaccine consisting of allogeneic, immortalized dendritic precursor cells derived from a patient with acute myelogenous leukemia (AML), with potential immunostimulatory and antineoplastic activities. Upon ex vivo stimulation and expansion of the precursor cells into mature, fully functional dendritic cells (DCs) and subsequent administration, the allogeneic AML antigen-expressing DC vaccine may elicit a potent cytotoxic T-cell (CTL) and antibody response against AML antigen-expressing cells, resulting in tumor cell death." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5020" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/146" ; obo:OGG_0000000006 "5788", "945" ; obo:VO_0001818 "5020" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD33|Gene name: PTPRC" ; rdfs:label "Allogeneic AML Antigen-expressing Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007218 obo:IAO_0000115 "An allogeneic whole cell vaccine, derived from irradiated allogenic tumor cells manipulated to express human B7.1 (CD80 antigen) and human leukocyte antigen (HLA) A1, with potential antitumor activity. Vaccination with allogeneic B7.1/HLA-A1 transfected tumor cell vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor cell proliferation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15254047", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4998" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/147" ; obo:OGG_0000000006 "941" ; obo:VO_0001818 "4998" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD80" ; rdfs:label "Allogeneic B7.1/HLA-A1 Transfected Tumor Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007219 obo:IAO_0000115 "A pluripotent, allogeneic, tumor cell vaccine composed of irradiated tumor cells from the non-small cell lung cancer (NSCLC) cell line 1650 and the immunoadjuvant recombinant granulocyte-macrophage colony stimulating factor (GM-CSF) (1650-G), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic cellular vaccine 1650-G may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against tumor-associated antigens (TAAs) expressed on NSCLC cells. GM-CSF potentiates the antitumor immune response. The 1650 cell line is used as a source for TAAs." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5257" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/148" ; obo:OGG_0000000006 "1048", "4101", "7490" ; obo:VO_0001818 "5257" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5|Gene name: WT1|Gene name: MAGEA2" ; rdfs:label "Allogeneic Cellular Vaccine 1650-G" ; rdfs:subClassOf obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007220 obo:IAO_0000115 "A cancer vaccine consisting of allogeneic, immortalized dendritic cells (DCs) loaded with tumor specific antigens and activated, with potential immunostimulatory and antineoplastic activities. Upon intratumoral administration of the allogeneic dendritic cell vaccine COMBIG-DC, these activated DCs attract natural killer (NK) cells, induce an anti-inflammatory response leading to the induction of NK-cell-mediated tumor cell death. Upon release of tumor associated antigens (TAAs) from the lysed tumor cells, these antigens are taken up by antigen presenting cells which activate the immune system to elicit a potent cytotoxic T-cell (CTL) response against the TAAs, resulting in the death of TAAs-expressing tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01525017", "NCT: https://clinicaltrials.gov/ct2/show/NCT01974661", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5446" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/149" ; obo:OGG_0000000006 "3458", "7124" ; obo:VO_0001818 "5446" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IFNG|Gene name: TNF" ; rdfs:label "Allogeneic Dendritic Cell Vaccine COMBIG-DC" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007221 obo:IAO_0000115 "A cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma idiotype with potential antineoplastic activity. Upon administration, allogeneic dendritic cell-myeloma idiotype vaccine may stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against myeloma cells, resulting in cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5102" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/150" ; obo:VO_0001818 "5102" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Allogeneic Dendritic Cell-Myeloma Idiotype Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007222 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from an allogeneic glioblastoma (GBM) stem-like cell line, with potential immunostimulatory and antineoplastic activities. Upon administration allogeneic glioblastoma stem-like cell line lysate-pulsed autologous dendritic cell vaccine exposes the immune system to GBM stem cell antigens, which may result in cytotoxic T lymphocyte (CTL) and antibody responses against GBM cells. This leads to GBM cell lysis. GBM stem-like cells contain a specific range of antigens that are essential for the neoplastic growth and survival of GBM cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5023" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/151" ; obo:OGG_0000000006 "7070" ; obo:VO_0001818 "5023" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD90" ; rdfs:label "Allogeneic Glioblastoma Stem-like Cell Line Lysate-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007223 obo:IAO_0000115 "An allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Upon vaccination, allogeneic GM-CSF-based myeloma cellular vaccine secretes GM-CSF, which may potentiate a tumor-specific cytotoxic T-lymphocyte (CTL) response against myeloma cancer cell-associated antigens." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5327" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/152" ; obo:OGG_0000000006 "1437", "4102", "7490", "9947" ; obo:VO_0001818 "5327" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM-SCF|Gene name: MAGEA3|Gene name: WT1|Gene name: MAGEC1" ; rdfs:label "Allogeneic GM-CSF-Based Myeloma Cell Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007224 obo:IAO_0000115 "An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified cells secrete GM-CSF, thereby potentiating a tumor-specific T cell response against breast cancer cell-asociated antigens.A vaccine that is being studied as a way to help the body's immune system kill breast cancer cells. To make the vaccine, the GM-CSF gene is put into breast cancer cells in the laboratory. The cells are then treated with radiation to stop them from growing and injected into the same or a different patient. The GM-CSF protein made by the changed breast cancer cells may help the immune system kill breast cancer cells in the body." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5059" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/153" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5059" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Allogeneic GM-CSF-Secreting Breast Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007225 obo:IAO_0000115 "An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Allogeneic GM-CSF-secreting tumor vaccine PANC 10.05 pcDNA-1/GM-Neo secretes GM-CSF thereby activating dendritic cells, promoting antigen presentation to B- and T-cells, and promoting a cytotoxic T-lymphocyte (CTL) response. This may eventually kill tumor cells. The pancreatic tumor cells are derived from the PANC 10.05 tumor cell line." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01088789", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5075" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/154" ; obo:VO_0001818 "5075" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Allogeneic GM-CSF-secreting Tumor Vaccine PANC 10.05 pcDNA-1/GM-Neo" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007226 obo:IAO_0000115 "An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Allogeneic GM-CSF-secreting tumor vaccine PANC 6.03 pcDNA-1/GM-Neo secretes GM-CSF thereby activating dendritic cells, promoting antigen presentation to B- and T-cells, and promoting a cytotoxic T-lymphocyte (CTL) response. This may eventually kill tumor cells. The pancreatic tumor cells are derived from the PANC 6.03 tumor cell line." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5515", "https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2010-01868&r=1" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/155" ; obo:VO_0001818 "5515" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Allogeneic GM-CSF-secreting Tumor Vaccine PANC 6.03 pcDNA-1/GM-Neo" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007227 obo:IAO_0000115 "A cancer vaccine, containing human-specific large multivalent immunogens (LMIs) isolated from the membrane fraction of cells from a breast cancer cell line, with potential immunostimulatory and antineoplastic activities. Upon administration, allogeneic large multivalent immunogen breast cancer vaccine may stimulate a cytotoxic T lymphocyte (CTL) immune response against tumor cells that express the breast cancer cell-specific LMIs." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5269" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/156" ; obo:OGG_0000000006 "1493" ; obo:VO_0001818 "5269" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTLA4" ; rdfs:label "Allogeneic Large Multivalent Immunogen Breast Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007228 obo:IAO_0000115 "A cancer vaccine, containing human-specific large multivalent immunogen (LMI) isolated from plasma membrane fractions of the melanoma cell lines MSM-M1 and MSM-M2, with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic large multivalent immunogen melanoma vaccine LP2307 may stimulate a CD8+ cytotoxic T lymphocyte (CTL) response against melanoma tumor cells that express melanoma-specific LMI." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00726739", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5423" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/157" ; obo:OGG_0000000006 "2315", "6490" ; obo:VO_0001818 "5423" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MLANA|Gene name: gp100 (PMEL)" ; rdfs:label "Allogeneic Large Multivalent Immunogen Melanoma Vaccine LP2307" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007229 obo:IAO_0000115 "A cancer vaccine derived from two gentically modified human melanoma cell lines with potential antineoplastic activity. Allogeneic melanoma vaccine AGI-101H consists of a 1:1 mixture of cells from two genetically modified human melanoma cell lines, designated as Mich1H6 and Mich2H6, that have been gamma-irradiated to render the cells non-proliferative. Upon administration, this vaccine may stimulate a cytotoxic immune response against melanoma tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:32002306", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5376" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/158" ; obo:OGG_0000000006 "216" ; obo:VO_0001818 "5376" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ALDH1A1" ; rdfs:label "Allogeneic Melanoma Vaccine AGI-101H" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007230 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with a mixture of lysates from five allogeneic mesothelioma tumor cell lines, with potential immunostimulatory and antineoplastic activities. Upon leukapheresis, DCs are loaded with allogeneic mesothelioma tumor cell lysates. Upon re-administration of the allogeneic mesothelioma tumor lysate-pulsed autologous DC vaccine, the immune system is exposed to an undefined amount of mesothelioma-associated antigens, which stimulates the induction of a specific cytotoxic T-lymphocyte (CTL) response against mesothelioma tumor cells and leads to tumor cell lysis" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5440" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/159" ; obo:OGG_0000000006 "10232" ; obo:VO_0001818 "5440" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MSLN" ; rdfs:label "Allogeneic Mesothelioma Tumor Lysate-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005491, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:MONDO_0005065 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007231 obo:IAO_0000115 "A biologic product that consists of undifferentiated stem cells, obtained from adult bone marrow or other non-embryonic tissue sources, that are expanded in vitro and deposited in master cell banks for \"\"off-the-shelf\"\" use, with potential hematopoiesis-inducing and immunomodulating activities. Allogeneic multipotent adult progenitor cells (MAPCs) are non-immunogenic due to the lack of major histocompatibility (MHC) molecule expression, and so elicit no immune response upon administration. In vivo, bone marrow-derived adult stem cells are capable of maturing into a broad range of cell types and may help restore the immune system by producing multiple therapeutic molecules in response to inflammation and tissue damage." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5054" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/160" ; obo:VO_0001818 "5054" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Allogeneic Multipotent Adult Progenitor Cells Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007232 obo:IAO_0000115 "A whole cell vaccine comprised of irradiated allogeneic renal cell carcinoma (RCC) with potential immunostimulating and antineoplastic activities. Allogeneic renal cell carcinoma vaccine MGN1601 contains two active ingredients: 1) genetically modified allogeneic RCC cells that are transiently transfected with four different MIDGE (Minimalistic Immunogenically Defined Gene Expression) vectors encoding IL-7, GM-CSF, CD80 and CD154 and 2) the synthetic DNA-based immunomodulator dSLIM-30L1, a TLR9 agonist.. Vaccination results in expression of IL-7, GM-CSF, CD80 and CD154, which all contribute to the activation or enhancement of immune responses. Furthermore, administration of this RCC vaccine may elicit a cytotoxic T lymphocyte (CTL) response against similar host tumor cells, resulting in decreased tumor growth. TLR9 is a member of the TLR family, which plays a fundamental role in pathogen recognition and activation of innate immunity." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5358", "https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)36654-0" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/161" ; obo:OGG_0000000006 "941", "959" ; obo:VO_0001818 "5358" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD80|Gene name: CD40LG" ; rdfs:label "Allogeneic Renal Cell Carcinoma Vaccine MGN1601" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007233 obo:IAO_0000115 "A vaccine composed of tumor cells isolated from the tumor of one patient, killed and processed, and administered to another patient to stimulate cytotoxic immune responses to a similar tumor cell type. The cells found in this type of whole-cell vaccine express many cell-surface tumor-associated antigens. This vaccine is frequently administered with an adjuvant immunostimulant." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5339", "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/allogeneic-tumor-cell-vaccine" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/162" ; obo:VO_0001818 "5339" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Allogeneic Tumor Cell Vaccine" ; rdfs:subClassOf obo:VO_0005430, obo:VO_0005484, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007234 obo:IAO_0000115 "A vaccine composed of killed glioma cancer cells from another patient for use in immunotherapy" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:24829761", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5119" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/163" ; obo:VO_0001818 "5119" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Allogenic Glioma Cancer Vaccine" ; rdfs:subClassOf obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007235 obo:IAO_0000115 "A vaccine consisting of a recombinant adenoviral vector encoding alpha fetoprotein. After vaccination, expressed alpha fetoprotein may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells that express alpha fetoprotein, resulting in tumor cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:25041030", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5313" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/164" ; obo:OGG_0000000006 "149" ; obo:VO_0001818 "5313" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: AFP" ; rdfs:label "Alpha Fetoprotein Adenoviral Vector Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007236 obo:IAO_0000115 "An allogeneic renal cell cancer (RCC) vaccine composed of cell line-derived RCCs that are genetically engineered to express the murine alpha-1,3-galactosyltransferase (GalT), with potential immunostimulatory and antineoplastic activities. Not naturally occurring in humans, GalT catalyzes the expression of foreign alpha-1,3-galactosyl (alpha-gal) carbohydrate epitopes on the cell membranes of the allogeneic RCCs present in the vaccine. This induces a hyperacute rejection reaction involving pre-existing human anti-alpha-gal antibodies, which bind to the foreign alpha-gal epitopes expressed by the allogeneic RCCs. This results in complement-mediated cytotoxicity (CMC) and antibody-dependent cell-mediated cytotoxicity (ADCC) towards endogenous RCCs with unmodified carbohydrate epitopes." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5349" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/165" ; obo:OGG_0000000006 "11605" ; obo:VO_0001818 "5349" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Gla" ; rdfs:label "Alpha-1,3-galactosyltransferase-expressing Allogeneic Renal Cell Carcinoma Vaccine" ; rdfs:subClassOf obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007237 obo:IAO_0000115 "A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with four alpha-fetoprotein (AFP) peptides, with potential immunostimulatory and antineoplastic activities. Upon administration, AFP peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against AFP-expressing cancer cells, resulting in tumor cell lysis. AFP is overexpressed in a variety of cancer cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:16675576", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5315" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/166" ; obo:OGG_0000000006 "174" ; obo:VO_0001818 "5315" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: AFP" ; rdfs:label "Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007238 obo:IAO_0000115 "A cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with the marine sponge glycolipid alpha-galactosylceramide (alpha-GalCer) with potential immunostimulatory and antimetastatic activities. Upon administration, alpha-galactosylceramide-pulsed autologous dendritic cells may result in the activation and proliferation of a subset of endogenous natural killer T (NKT) cells, B cells, and CD4+ and CD8+ T cells, and the production of interferon-gamma and interleukin-12; these cascade events may result in a T helper-1 cell-biased proinflammatory antitumor immune response. The NKT cell ligand alpha-GalCer was originally isolated from the marine sponge Agelas mauritianusis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:32188702", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5288" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/167" ; obo:VO_0001818 "5288" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Alpha-Galactosylceramide-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007239 obo:IAO_0000115 "A mature polarized dendritic cell with potent immunostimulating activity. Treating dendritic cells (DCs) with interferon-alpha (IFN-a) and polyinosinic:polycytidylic acid (p-I:C) in addition to a cytokine cocktail (tumor necrosis factor alpha/Interleukin-1beta/IFN-gamma) produces mature but not exhausted alpha type-1 polarized DCs (alphaDC1) that are capable of: 1) high responsiveness to other lymphoid chemokines, and 2) producing high level of interleukin-12p70 (IL-12p70). Therefore, alphaDC1 has a much more significant capability of inducing helper T cell (CD4+ T-cell) responses in comparison with the \"\"gold standard\"\" DCs. When pulsed with specific tumor associated antigens (TAAs), alphaDC1 is able to induce a potent cytotoxic T lymphocyte (CTL) response against TAAs; as a result it can be used as a cancer vaccine." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5198", "https://www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/alpha-type-1-polarized-dendritic-cells" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/168" ; obo:OGG_0000000006 "2315", "6490", "7299" ; obo:VO_0001818 "5198" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MLANA|Gene name: gp100 (PMEL)|Gene name: Tyrosinase" ; rdfs:label "Alpha-type-1 Polarized Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1964 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007240 obo:IAO_0000115 "A derivative of the Canarypox Virus, ALVAC can infect mammalian cells but it can't replicate. Thus, it produces a self-limiting infection which does not produce symptoms or harm the host. When carrying foreign genes it will cause transient expression of protein." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:16061912", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5334" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/169" ; obo:OGG_0000000006 "3458" ; obo:VO_0001818 "5334" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IFNG -Obselete " ; rdfs:label "ALVAC Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007241 obo:IAO_0000115 "A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus. ALVAC-B7-CEA expresses carcinoembryonic antigen (CEA), a protein that is overexpressed by many tumor cells, and B7.1 (also known as CD80), the natural ligand for the T-cell antigen CD28, to augment the host immune response. This agent has been shown to stimulate a host immune response against tumor cells that express CEA. (NCI04)" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:12596363", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5444" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/210" ; obo:OGG_0000000006 "1048", "941" ; obo:VO_0001818 "5444" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD80|Gene name: CEACAM5 (CEA)" ; rdfs:label "ALVAC-B7-CEA Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007242 obo:IAO_0000115 "A replication-defective recombinant canarypox virus (ALVAC) that contains the entire human carcinoembryonic antigen (CEA) gene. Vaccination with ALVAC-CEA (VCP248) may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against CEA-positive tumor cells, thereby decreasing tumor growth. (NCI04)" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5003" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/212" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5003" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "ALVAC-CEA (VCP248) Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007243 obo:IAO_0000115 "A cancer vaccine that uses a viral vector system derived from the canarypox virus engineered to target the carcinoembryonic antigen (CEA). It causes infected cells to temporarily display CEA and activates the immune system to attack the tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:18676757", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5125" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/213" ; obo:OGG_0000000006 "941" ; obo:VO_0001818 "5125" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD80" ; rdfs:label "ALVAC-CEA B7.1 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007244 obo:IAO_0000115 "A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus, encoding for the tumor associated antigen (TAA) carcinoembryonic antigen (CEA), with potential antineoplastic activity. Upon administration, ALVAC-CEA vaccine expresses CEA and may stimulate a host immune response against tumor cells expressing CEA. This may result in the inhibition of tumor growth and/or metastasis. CEA is overexpressed in a variety of tumor cell types." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5051" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/214" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5051" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "ALVAC-CEA Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007245 obo:IAO_0000115 "A cancer vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) encoding the cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon administration, ALVAC-ESO-1 vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against NY-ESO-1-expressing cancer cells, which may result in the inhibition of tumor cell proliferation. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01982487", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5332" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/215" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5332" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "ALVAC-ESO-1 Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007246 obo:IAO_0000115 "A vaccine comprise of a canarypox viral vector that carries the gene for human B7.1 (CD80 antigen) with potential use as an autologous therapeutic cancer vaccine. Tumor cells harvested from a patient are infected with ALVAC-hB7 1, thereby producing an autologous cell line that exhibits increased expression of HLA class I and class II, CD54 (ICAM), and CD80. Increased expression of these proteins by this autologous cell line may activate an antitumor T-cell response when the modified cells are administered to the patient." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00003556", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5181" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/216" ; obo:OGG_0000000006 "1493" ; obo:VO_0001818 "5181" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTLA4" ; rdfs:label "ALVAC-hB7.1 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007247 obo:IAO_0000115 "A cancer vaccine containing a replication-defective recombinant canarypox virus (ALVAC), encoding an epitope of MART-1 (melanoma antigen recognized by T-cells), with potential immunostimulatory and antineoplastic activities. Upon administration, the MART-1 epitope is expressed by the ALVAC vector in ALVAC-MART-1 vaccine; a host cytotoxic T lymphocyte (CTL) response against MART-1-expressing tumor cells may follow, resulting in tumor cell lysis and decreased tumor cell proliferation" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00612222", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5124" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/217" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5124" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MLANA" ; rdfs:label "ALVAC-MART-1 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007249 obo:IAO_0000115 "A therapeutic cancer vaccine, based on a replication-defective recombinant canarypox virus (ALVAC) encoding multiple melanoma antigens, with potential immunostimulatory and antineoplastic activities. Vaccination with ALVAC(2) melanoma multi-antigen therapeutic vaccine may stimulate the host immune system to mount an immune response against antigen-expressing melanoma cells, resulting in inhibition of tumor growth and/or metastasis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5394" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/170" ; obo:OGG_0000000006 "1485", "6490" ; obo:VO_0001818 "5394" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)|Gene name: CTAG1B" ; rdfs:label "ALVAC(2) Melanoma Multi-antigen Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007250 obo:IAO_0000115 "A cancer vaccine consisting of a replication-defective recombinant canarypox virus [ALVAC(2)] encoding the cancer-testis antigen NY-ESO and the TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3; also called TRICOM), with potential immunostimulatory and antineoplastic activities. Upon administration, ALVAC(2)/NY-ESO (M)/TRICOM vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against NY-ESO-expressing cancer cells, which may result in the inhibition of tumor cell proliferation. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cells, including bladder, breast, hepatocellular, melanoma, and prostate tumor cells. TRICOM may enhance antigen presentation and activate cytotoxic T-cells. In addition, ALVAC(2) encodes the vaccinia virus (vv) E3L ad K3L genes, which may potentiate the translation of the NY-ESO and TRICOM genes." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01982487", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5268" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/171" ; obo:OGG_0000000006 "1485", "3383", "941", "965" ; obo:VO_0001818 "5268" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1|Gene name: ICAM1|Gene name: CD80|Gene name: CD58" ; rdfs:label "ALVAC(2)-NY-ESO-1 (M)/TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007251 obo:IAO_0000115 "A cancer vaccine consisting of autologous dendritic cells loaded with separate preparations of acute myelogenous leukemia (AML) cell lysate and AML-specific messenger RNA (mRNA) with potential immunostimulatory and antineoplastic activities. Upon administration, AML mRNA plus lysate loaded autologous dendritic cell vaccine may elicit a potent cytotoxic T-cell (CTL) response against AML cells, resulting in tumor cell death. Autologous dendritic cells doubly-loaded with AML cell lysate and AML-specific mRNA may elicit superior primary, recall, and effector lytic immune responses compared to autologous dendritic cells loaded with tumor lysate or tumor mRNA alone." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5533" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/219" ; obo:VO_0001818 "5533" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "AML mRNA Positive Lysate Loaded Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007252 obo:IAO_0000115 "A plasmid DNA-based vaccine consisting of small biodegradable poly(lactide-co-glicolide) polymer microparticles encapsulating plasmid-DNA vector encoding a chimeric protein comprising epitopes derived from the E6 and E7 oncoproteins of the human papillomavirus (HPV) types 16 and 18, with potential antineoplastic activity. Upon intramuscular vaccination, amolimogene bepiplasmid may elicit the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV-16 and -18 E6 and E7 and may result in a reduction in tumor cell growth. HPV types 16 and 18 oncoproteins E6 and E7 are most commonly involved in cervical cancer." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:19051140", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5243" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/220" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "5243" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7" ; rdfs:label "Amolimogene Bepiplasmid Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007253 obo:IAO_0000115 "A cancer vaccine containing pTVG4 plasmid DNA encoding the human androgen receptor (AR) ligand-binding domain (LBD) (pTVG-AR), with potential immunostimulating and antineoplastic activities. Upon intradermal administration of AR LBD-encoding plasmid DNA vaccine MVI-118, the plasmid DNA vaccine expresses AR LBD and may stimulate the host immune system to generate a cytotoxic T-lymphocyte (CTL) response against AR LBD-expressing prostate cancer cells. This reduces proliferation of AR-expressing tumor cells. AR, a tumor-associated antigen (TAA) overexpressed in prostate cancer cells, plays a key role in the development and progression of prostate cancer; its expression is correlated with poor prognosis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:32513836", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5331" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/221" ; obo:OGG_0000000006 "367" ; obo:VO_0001818 "5331" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: AR" ; rdfs:label "Androgen Receptor Ligand-binding Domain-encoding Plasmid DNA Vaccine MVI-118" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007254 obo:IAO_0000115 "A modified vaccinia Ankara (MVA) encoding 7 melanoma tumor antigen cytotoxic T lymphocyte (CTL) epitopes." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15627214", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3994" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/222" ; obo:VO_0001818 "3994" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Ankara (MVA) Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007255 obo:IAO_0000115 "Recombinant MVA-gp100M and ALVAC(2)-5T4 were constructed to complement existing ALVAC(2)-gp100M and MVA-5T4 vectors. Recombinant TAA expression in chicken embryo fibroblast cells was confirmed by Western blot analysis. 5T4 expression was approximately equal for both viruses, whereas ALVAC-derived gp100 was quickly degraded, at a time point when MVA-derived gp100 was still stable and expressed at high levels" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15627214", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4073" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/223" ; obo:VO_0001818 "4073" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Ankara (MVA) and ALVAC(2) Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007256 obo:IAO_0000115 "An anti-CD19/anti-CD3 bispecific tetravalent antibody with potential immunostimulatory and antineoplastic activities. Anti-CD19/CD3 tetravalent antibody AFM11 possesses two antigen-recognition and binding sites, one for the CD3 complex, a group of T-cell surface glycoproteins that complex with the T-cell receptor (TCR), and one for CD19, a tumor-associated antigen (TAA) overexpressed on the surface of B-cells. Upon bolus infusion of AFM11, this bispecific antibody binds to CD3-expressing T-cells and CD19-expressing cancer cells, thereby crosslinking CD19-expressing tumor B-cells and cytotoxic T-lymphocytes (CTLs). This may result in a potent CTL-mediated cell lysis of CD19-expressing B-lymphocytes. CD19, a B-cell specific membrane antigen, is expressed during both B-cell development and B-cell malignant growth." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5199" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/224" ; obo:VO_0001818 "5199" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Anti-CD19/CD3 Tetravalent Antibody AFM11 Vaccine" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007257 obo:IAO_0000115 "Autologous activated T cells that have been coated with bispecific antibodies (BiAb), with potential antineoplastic and immunomodulating activities. In vitro, T cells are activated through exposure to the anti-CD3 murine monoclonal antibody OKT3 and low-dose interleukin 2 (Il-2) for 6-14 days and then armed with anti-CD3 x anti-CD20 bispecific antibody (CD20Bi). Upon administration, anti-CD3 x anti-CD20 bispecific antibody-armed activated T cells (AATC) attach to CD3-expressing T cells and CD20-expressing tumor cells, selectively cross-linking T cells and tumor cells. This may result in the recruitment and activation of cytotoxic T lymphocyte (CTLs), CTL-mediated specific tumor cell lysis, and the secretion of antitumor cytokines and chemokines. CD20, a cell surface phosphoprotein, is found on normal B cells and most B-cell tumors." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5411", "https://www.targetedonc.com/view/cd20-cd3-bispecific-antibodies-can-revolutionize-b-cell-lymphoma-therapy" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/225" ; obo:OGG_0000000006 "931" ; obo:VO_0001818 "5411" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MS4A1" ; rdfs:label "Anti-CD3 x Anti-CD20 Bispecific Antibody-Armed Activated T Cells Cancer Vaccine" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007258 obo:IAO_0000115 "Autologous human peripheral blood lymphocytes (PBLs), transduced with a retroviral vector encoding both the alpha and beta chains of a T cell receptor (TCR) specific for the carcinoembryonic antigen (CEA), with potential immunostimulating and antineoplastic activities. After transduction, expansion in culture, and reintroduction into the patient, anti-CEA TCR retroviral vector-transduced autologous lymphocytes bind to tumor cells expressing CEA, which may result in cytokine expression, activation and proliferation of T-cells, and a specific cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells. The tumor-associated antigen (TAA) CEA is overexpressed by a variety of cancer cell types, including those of the gastrointestinal tract, lung, and breast." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5536" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/226" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5536" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "Anti-CEA TCR Retroviral Vector-Transduced Autologous Peripheral Blood Lymphocytes" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007259 obo:IAO_0000115 "An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA-transfected autologous DC vaccine is prepared by transfecting DCs with RNAs encoding humanized heavy and light chains of the anti-CTLA4 (cytotoxic T-Lymphocyte-Associated Antigen 4); expression of anti-CTLA4 blocks the inhibitory effect of CTLA4 on the activation of T-lymphocytes. Co-vaccination of this vaccine with melanoma antigen specific vaccine may eliminate the adverse effects associated with systemic administration of immune modulators, while also enhancing vaccine-induced immune responses" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5375" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/227" ; obo:OGG_0000000006 "1493" ; obo:VO_0001818 "5375" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTLA4" ; rdfs:label "Anti-CTLA4 MoAb RNA-transfected Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0007260 obo:IAO_0000115 "An autologous dendritic cell (DC) cancer vaccine with potential immunostimulatory activity. Anti-CTLA4 MoAb RNA/GITRL RNA-transfected DC vaccine is prepared by transfecting DCs with RNAs encoding humanized heavy and light chains of the anti-CTLA4 (cytotoxic T-Lymphocyte-Associated Antigen 4) monoclonal antibody and tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18 or GlTRL); expression of anti-CTLA4 blocks the inhibitory effect of CTLA4 on the activation of T-lymphocytes, while expression of GlTRL modulates T lymphocyte survival in peripheral tissues. Co-vaccination of this vaccine with melanoma antigen specific vaccine may eliminate the adverse effects associated with systemic administration of immune modulators, while also enhancing vaccine-induced immune responses." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5149" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/228" ; obo:OGG_0000000006 "1493" ; obo:VO_0001818 "5149" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTLA4" ; rdfs:label "Anti-CTLA4 MoAb RNA/GITRL RNA-transfected Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007261 obo:IAO_0000115 "A peptide vaccine derived from the synthetic peptide pyroEHWSYGLRPG, corresponding to amino acids 22-31 of mouse gonadotropin releasing hormone (GnRH), with potential immunocastration activity. PEP223 is dimerized and contains a D-lysine (k) substitution at position 6 (pyroEHWSYkLRPG) to increase its immunogenicity. Anti-GnRH vaccine PEP223 may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against GnRH, neutralizing its activity. In turn, testosterone production and tumor cell growth may be inhibited in testosterone-sensitive tumors." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00895466", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5405" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/229" ; obo:OGG_0000000006 "14714" ; obo:VO_0001818 "5405" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Gnhr1" ; rdfs:label "Anti-GnRH Vaccine PEP223" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007262 obo:IAO_0000115 "A monoclonal antibody that functionally mimics MUC-1 antigen, a tumor cell surface antigen. Administration of anti-idiotype MUC-1 monoclonal antibody may elicit an anti-idiotype antibody and corresponding T-cell response against MUC-1 expressing tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15550589", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5175" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/230" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5175" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "Anti-idiotype MUC-1 Monoclonal Antibody Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007263 obo:IAO_0000115 "A synthetic antibody produced by a genetically homogenous population of hybrid cells (hybridoma) against determinant idiotypes (Id) which usually mimic human epitopes. Anti-Id vaccines may be effective in the treatment of B-cell lymphomas, resulting in tumor regression. Anti-idiotype vaccine therapy is less likely to induce autoimmunity if the target antigen is not normally expressed on normal tissues. Monoclonal antibodies have become powerful tools for tumor targeting, recognizing different protein markers on certain cancer cells and may be used alone or as delivery agents for drugs, toxins or radioactive material targeted to tumors." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5301" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/231" ; obo:VO_0001818 "5301" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Anti-Idiotype Specified Monoclonal Antibody Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007264 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:/9816036", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4015" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/232" ; obo:VO_0001818 "4015" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "anti-idiotypic (anti-id) mAb MK2-23 + BCG" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007265 obo:IAO_0000115 "A murine anti-idiotypic monoclonal antibody (anti-Id MoAb) that is directed against an idiotype mimicking a disialoganglioside GD3. GD3 represents a major surface marker on most human melanoma cells. Due to poor immunogenicity of GD3, anti-Id MoAb BEC2 (Ab2) was raised against a mouse anti-GD3 MoAb, R24 (Ab1). This anti-Id MoAb was shown to be functionally mimicking GD3 in stimulating an immune response to produce Ab3 that may be used in combination with other adjuvants for treatment of melanomas." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5433" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/233" ; obo:VO_0001818 "5433" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Anti-idiotypic Monoclonal Antibody BEC2 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007266 obo:IAO_0000115 "An immunotherapeutic agent targeting the tumor-associated antigen (TAA), cancer/testis antigen NY-ESO-1, with potential antineoplastic activity." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5485" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/234" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5485" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "Anti-NY-ESO-1 Immunotherapeutic GSK-2241658A Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007267 obo:IAO_0000115 "Human autologous CD62L-positive T-lymphocytes transduced with a retroviral vector encoding a T cell receptor (TCR) specific for the cancer-testis antigen NY-ESO-1, with potential antineoplastic activity. Following leukapheresis, isolation of lymphocytes, expansion ex vivo, transduction, and reintroduction into the patient, the anti-NY-ESO1 TCR-transduced autologous CD62L+-derived T-Lymphocytes bind to NY-ESO-1-overexpressing tumor cells. This may result in cytotoxic T-lymphocyte (CTL)-mediated elimination of NY-ESO-1-positive cancer cells. NY-ESO-1, a tumor associated antigen (TAA), is found in normal testis and on the surface of various tumor cell types. CD62L, also called L-selectin, is a lymphoid homing receptor and differentiation marker and is expressed on a subset of CD8-positive T-lymphocytes; it is involved in the migration of T-lymphocytes to lymph nodes and may improve the efficacy for ex vivo-expanded T-cells following adoptive cell therapy." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5081" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/235" ; obo:OGG_0000000006 "1485", "30484" ; obo:VO_0001818 "5081" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1|Gene name: CTAG2" ; rdfs:label "Anti-NY-ESO1 TCR-transduced Autologous CD62L+-derived T-Lymphocytes Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007268 obo:IAO_0000115 "Human autologous peripheral blood lymphocytes (PBLs) transduced with an anti-p53 T cell receptor gene with potential antineoplastic activity. PBLs are harvested from a patient and pulsed with a retroviral vector that encodes the T-cell receptor gene specific for a mutated form of p53. The transduced PBLs are then expanded in culture. When reintroduced to the patient, these modified PBLs express the anti-p53 T cell receptor which binds to mutant p53-overexpressing tumor cells; PBL-mediated tumor growth inhibition may follow. Many tumor cell types overexpress mutant p53 proteins, which are associated with the loss of apoptosis regulation and abnormal cell proliferation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00393029", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5447" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/236" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "5447" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53 (P53)" ; rdfs:label "Anti-p53 T-Cell Receptor-Transduced Peripheral Blood Lymphocytes Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007269 obo:IAO_0000115 "An immunotherapeutic agent targeting the tumor-associated antigen (TAA), preferentially expressed antigen of melanoma (PRAME), with potential antineoplastic activity." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01853878", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5361" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/237" ; obo:OGG_0000000006 "23532" ; obo:VO_0001818 "5361" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PRAME" ; rdfs:label "Anti-PRAME Immunotherapeutic GSK2302032A Vaccine" ; rdfs:subClassOf obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007270 obo:IAO_0000115 "An individualized, therapeutic cancer vaccine (IVAC) composed of liposomes containing RNA encoding two or three tumor associated antigens (TAAs) that are specifically expressed in the patient's individual cancer selected from a warehouse (\"\"off the shelf\"\") and p53 RNA, with potential immunostimulatory and antineoplastic activities. Upon administration, the antigen-targeted personalized breast cancer vaccines are translated by antigen presenting cells (APCs) and the expressed protein is presented via major histocompatibility complex (MHC) molecules on the surface of the APCs. This leads to an induction of both cytotoxic T-lymphocyte (CTL) and memory T-cell immune responses against the TAAs. The RNAs in the vaccine are specifically selected for an individual patient after RNA profiling of the patient's tumor." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5138" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/238" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5138" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)" ; rdfs:label "Antigen-targeted Personalized Breast Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007271 obo:IAO_0000115 "A cell-based vaccine composed of previously frozen autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expressing PAP." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01133704", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5420" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/239" ; obo:OGG_0000000006 "2346", "354", "55" ; obo:VO_0001818 "5420" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ACPP|Gene name: Prostate|Gene name: KLK3" ; rdfs:label "APC8015F Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007272 obo:IAO_0000115 "A cell based cancer vaccine composed of mature polarized dendritic cells (DCs) and pulsed with apoptotic autologous tumor cells that has potential immunostimulating and antineoplatic activities. Dendritic cells (DCs) were treated with interleukin-1beta, tumor necrosis factor alpha, interferon-alpha (IFN-a), IFN-gamma and polyinosinic:polycytidylic acid (p-I:C) to produce mature alpha type-1 polarized DCs (alphaDC1) that are capable of producing high levels of interleukin-12p70 (IL-12p70). The alphaDC1 are subsequently pulsed with apoptotic autologous tumor cells. Upon administration, these DCs are able to induce a potent cytotoxic T lymphocyte (CTL) response against tumor associated antigens (TAAs), resulting in tumor cell lysis and inhibition of tumor cell growth. Apoptotic tumor cells contain an array of TAAs" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:21509164", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5222" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/240" ; obo:VO_0001818 "5222" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Apoptotic Autologous Tumor Cells-pulsed Alpha-type-1 Polarized Dendritic Cells Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007274 obo:IAO_0000115 "A vaccine comprised of autologous epithelial ovarian cells infected with ALVAC-hB7.1" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5319", "https://www.clincosm.com/trial/recurrent-ovarian-epithelial-cancer-houston-alvac-hb71-recombinant" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/242" ; obo:OGG_0000000006 "155971" ; obo:VO_0001818 "5319" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: env" ; rdfs:label "AUT-OV-ALVAC-hB7.1 Vaccine" ; rdfs:subClassOf obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007275 obo:IAO_0000115 "An autologous tumor cell vaccine containing chronic lymphocytic leukemia (CLL) B cells transduced with an adenoviral vector carrying chimeric CD154 (ad-CD154) with potential antineoplastic activity. Administration of autologous ad-CD154 transduced CLL B cells may result in increases in the numbers of leukemia-specific CD4+ T cells and high serum-levels of IL-12 and IFN-gamma. Due to ligation of CD154 to CD40 on CLL cells, this agent may induce CLL cells to express the proapoptotic molecule BID and death receptors CD95 (Fas) and DR5, rendering CLL B cells first resistant and then sensitive to Fas-mediated apoptosis. In addition, autologous ad-CD154 transduced CLL B cells may induce MHC class I-dependent cytotoxic T lymphocyte (CTL) responses against autologous leukemia cells. CD154 is a type II membrane glycoprotein and ligand for CD40; both molecules are important in cognate co-stimulatory cell-cell interactions." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00779883", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5053" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/243" ; obo:OGG_0000000006 "959" ; obo:VO_0001818 "5053" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD40LG" ; rdfs:label "Autologous Ad-CD154-Transduced CLL B Cells Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007276 obo:IAO_0000115 "Human autologous peripheral blood lymphocytes (PBLs) transduced with a glycoprotein 100 (gp100) epitope-determined T cell receptor (TCR) gene, with potential antineoplastic activity. PBLs are isolated from a melanoma patient and pulsed with a viral vector encoding the TCR specific for amino acid residues 154-162 of gp100 (KTWGQYWQV). After expansion ex vivo, the transduced autologous PBLs, expressing this specific TCR, are reintroduced into the patient and bind to melanoma cells expressing the gp100 protein, which may result in specific cytotoxic T-lymphocyte (CTL) killing of gp100-expressing melanoma cells. gp100 is a melanocyte lineage-specific antigen overexpressed in melanomas." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00509496", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5507" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/244" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5507" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)" ; rdfs:label "Autologous Anti-gp100:154-162 T-Cell Receptor Gene-Engineered Peripheral Blood Lymphocytes Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007277 obo:IAO_0000115 "Human autologous peripheral blood lymphocytes (PBLs) transduced with a melanoma antigen MART-1 epitope-determined T cell receptor (TCR) gene, with potential antineoplastic activity. PBLs are isolated from a melanoma patient and pulsed with a viral vector that encodes the TCR specific for an epitope of MART-1 (F5 TCR). After expansion ex vivo, the transduced autologous PBLs, expressing this specific TCR, are reintroduced into the patient, and bind to melanoma cells expressing the MART-1 antigen, which may result in specific cytotoxic T-lymphocyte (CTL) killing of MART-1-expressing melanoma cells. MART-1 (melanoma antigen recognized by T cells 1), also known as Melan-A, is a melanocyte lineage-specific transmembrane protein." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00509288", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5293" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/245" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5293" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MLANA" ; rdfs:label "Autologous Anti-MART-1 F5 T-Cell Receptor Gene-Engineered Peripheral Blood Lymphocytes Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007278 obo:IAO_0000115 "A cancer vaccine consisting of autologous dendritic cells (DCs) loaded with CD133-positive autologous brain tumor stem cells (BTSCs) -derived mRNA with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, autologous CD133-positive BTSC mRNA-pulsed autologous dendritic cell vaccine may elicit a cytotoxic T-lymphocyte (CTL) response against the CD133-positive BTSCs from which the autologous tumor mRNA is derived. CD133, a tumor-associated antigen (TAA) and neural stem cell marker, has been found on a specific subset of glioblastoma multiforme (GBM) stem cells; its presence has been correlated with resistance to conventional chemotherapy and radiotherapy." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5463", "https://mhlw-grants.niph.go.jp/system/files/2013/134041/201328051A/201328051A0017.pdf" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/246" ; obo:OGG_0000000006 "8842" ; obo:VO_0001818 "5463" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PROM1" ; rdfs:label "Autologous CD133-Positive BTSC mRNA-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007279 obo:IAO_0000115 "A cancer vaccine consisting of autologous, B-chronic lymphocytic leukemia (B-CLL) cells harvested from a patient and transduced with an adenoviral vector encoding the gene for the human CD40 ligand (CD40L; TRAP; CD154), with potential immunostimulating and antineoplastic activities. Upon reintroduction into the patient, the autologous CD40L-expressing B-CLL vaccine expresses the co-stimulatory molecule CD40L, which binds to its cognate receptor, CD40, on antigen presenting cells (APC). This induces apoptosis, stimulates maturation and proliferation of APCs, and facilitates a cytotoxic T-lymphocyte (CTL) response against tumor cells. CD40L is a type II membrane protein that binds to CD40, which is a cell surface receptor that belongs to the tumor necrosis factor (TNF) receptor superfamily." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5174" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/247" ; obo:OGG_0000000006 "959" ; obo:VO_0001818 "5174" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD40LG" ; rdfs:label "Autologous CD40L-expressing B-CLL Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007280 obo:IAO_0000115 "A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with tumor cell lysates from a colorectal cancer patient containing tumor-associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous colorectal tumor antigen-pulsed DC vaccine exposes the immune system to colorectal tumor cell antigens, which may result in cytotoxic T-lymphocyte (CTL)-mediated immune responses against the colorectal cancer cells. This leads to cancer cell lysis. The tumor cell lysate contains a range of antigens that are essential for the neoplastic growth and survival of the cancer cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5150" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/248" ; obo:OGG_0000000006 "174" ; obo:VO_0001818 "5150" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: AFP" ; rdfs:label "Autologous Colorectal Tumor Antigen-pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007281 obo:IAO_0000115 "An autologous tumor cell vaccine containing CD34+ hematopoietic progenitor cell (HPC)-derived Langerhans-type dendritic cells (LCs) electroporated with mRNA encoding the full-length cancer-testis antigens, CT7 and melanoma-associated antigen 3 (MAGE-A3), and the self-differentiation tumor antigen, Wilms tumor 1 (WT1) with potential immunomodulating and antineoplastic activity. The autologous CT7/MAGE-A3/WT1 mRNA-electroporated Langerhans-type dendritic cells are prepared by drawing a blood sample containing the CD34+ HPCs from a cancer patient. The CD34+ HPCs are treated with a combination of cytokines which specifically support LC development, and the LC population is enriched and expanded ex vivo. The cultured LCs are allowed to mature for one day and then electroporated separately with CT7, MAGE-A3 or WT1 mRNA before final maturation. Upon intradermal administration into the patient, the mature LCs may activate cell-mediated immunity and induce both cytotoxic CD8+ T cells and CD4+ helper T cells against cancer cells expressing CT7, MAGE-A3 and WT1 tumor antigens. This may result in the immune-mediated inhibition of tumor cell proliferation, leading to tumor cell death. CT7 and MAGE-A3 are tumor-specific proteins overexpressed in a number of cancers but not in healthy tissues other than testis and placenta. WT1 is a transcription factor important in development and cancer pathogenesis, which is overexpressed in a variety of cancers, including multiple myeloma, leukemia, ovarian cancer, malignant mesothelioma, neural tumors and renal carcinoma." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01995708", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5128" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/249" ; obo:OGG_0000000006 "7490" ; obo:VO_0001818 "5128" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WT1" ; rdfs:label "Autologous CT7/MAGE-A3/WT1 mRNA-Electroporated Langerhans-Type Dendritic Cells Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007282 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:22774527", "PubMed:31771601", "PubMed:34862245", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3967" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/250" ; obo:VO_0001818 "3967" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "autologous dendritic cell vaccine (DCV)" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3068 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007283 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous, immature dendritic cells (DCs), with potential immunostimulating and antineoplastic activities. Upon leukapheresis, immature DCs are isolated and re-administered intra-tumorally. The immature DCs internalize and process the tumor-associated antigens (TAAs), migrate to the lymphatic system, and then expose the immune system to the TAAs. This induces a specific cytotoxic T-lymphocyte (CTL) response against the cancer cells leading to tumor cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT02649829", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5085" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/251" ; obo:OGG_0000000006 "958" ; obo:VO_0001818 "5085" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:hasAlternativeId "VO:0007576" ; a owl:Class ; rdfs:comment "Gene name: CD40" ; rdfs:label "Autologous Dendritic Cell Vaccine ACT2001" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005491, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:MONDO_0005065 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007284 obo:IAO_0000115 "A cancer vaccine comprised of autologous dendritic cells (DCs) that have been transduced ex vivo with an adenoviral vector containing the CCL21 gene with potential immunostimulatory and antineoplastic activities. Upon intratumoral administration, autologous dendritic cell-adenovirus CCL21 vaccine expresses the chemokine CCL21, which may induce an antitumoral cytotoxic immune response in the tumor microenvironment. CCL21 [chemokine (C-C motif) ligand 21] has been shown to attract antigen presenting cells (APCs), like leukocytes and DCs, and natural killer (NK) cells and their T-cell effectors to induce a cytotoxic immune response." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT03546361", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5030" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/252" ; obo:OGG_0000000006 "6366" ; obo:VO_0001818 "5030" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CCL21" ; rdfs:label "Autologous Dendritic Cell-Adenovirus CCL21 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007285 obo:IAO_0000115 "An autologous vaccine composed of dendritic cells (DC) that have been transduced with a p53 tumor suppressor gene-modified virus. When the autologous dendritic cell-adenovirus p53 vaccine is administered, the host cytotoxic T lymphocytes (CTL) are directed against p53-positive tumor cells, which may result in tumor cell death and decreased tumor growth." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:20420527", "PubMed:29515795", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5088" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/253" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "5088" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53 (P53)" ; rdfs:label "Autologous Dendritic Cell-Adenovirus P53 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5409 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007286 obo:IAO_0000115 "A cell-based vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from heat-treated allogeneic melanoma tumor cells. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T-cell and antibody responses to melanoma cells bearing shared melanoma antigens such as MelanA/MART-1, gp100, MAGE3, resulting in tumor cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5495" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/254" ; obo:OGG_0000000006 "2315", "4102", "6490" ; obo:VO_0001818 "5495" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MLANA|Gene name: gp100 (PMEL)|Gene name: MAGEA3" ; rdfs:label "Autologous Dendritic Cell-Allogeneic Melanoma Tumor Cell Lysate Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007287 obo:IAO_0000115 "cancer vaccine consisting of autologous dendritic cells transfected with autologous tumor mRNA and the human CD40 ligand (CD40L) gene with immunostimulatory and antitumor activities. Vaccination with autologous dendritic cell-autologous tumor mRNA-human CD40L vaccine may elicit a cytotoxic T cell response against tumor cells from which the autologous tumor mRNA was derived. When expressed by dendritic cells, tumor antigens and the co-stimulatory molecule CD40L, which binds to CD40 receptors on antigen presenting cells (APC), facilitate both humoral and cellular immune responses against tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:20884622", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5066" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/255" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5066" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)" ; rdfs:label "Autologous Dendritic Cell-Autologous Tumor mRNA-Human CD40L Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007288 obo:IAO_0000115 "A therapeutic interleukin-12 (IL-12)-expressing dendritic cell (DC)-based vaccine composed of autologous monocyte-derived DCs loaded with autologous tumor cell lysate and exposed to the microbial cell wall component lipopolysaccharide (LPS), with potential immunomodulating and antineoplastic activities. The monocyte-derived immature DCs are loaded with autologous tumor cell lysates and are subsequently exposed to LPS and interferon-gamma (IFN-gamma). Upon administration of autologous DC-based immunotherapeutic AV0113, the mature DCs migrate into the lymph nodes, express the immune stimulatory cytokine interleukin-12 (IL-12) and activate the immune system by promoting the activation of natural killer (NK) cells and induce a cytotoxic T-lymphocyte (CTL)-mediated immune response against tumor cells, which may result in immune-mediated tumor cell death and inhibition of tumor cell proliferation. Exposure to LPS and IFN-gamma allows the maturation of DCs and optimizes the presentation of tumor-associated antigens (TAAs) by DCs to T-lymphocytes." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5284", "https://ascopubs.org/doi/10.1200/jco.2014.32.15_suppl.2052" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/256" ; obo:VO_0001818 "5284" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous Dendritic Cell-based Immunotherapeutic AV0113 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007289 obo:IAO_0000115 "A therapeutic cancer vaccine consisting of autologous dendritic cells (DCs) fused with autologous tumor cells with potential immunostimulatory and antineoplastic activities. Autologous dendritic cell-tumor fusion vaccine is generated in vitro by mixing DCs and irradiated tumor cells harvested from individual patients and treating them with polyethylene glycol (PEG) to produce DC-tumor cell fusion hybrid cells. Upon administration, autologous dendritic cell-tumor fusion vaccine may elicit antitumor humoral and cellular immune responses." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:23685836", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5056" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/257" ; obo:OGG_0000000006 "4582", "6382", "952" ; obo:VO_0001818 "5056" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:hasAlternativeId "VO:0007577" ; a owl:Class ; rdfs:comment "Gene name: MUC1|Gene name: CD38|Gene name: SDC1" ; rdfs:label "Autologous Dendritic Cell-Tumor Fusion Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007290 obo:IAO_0000115 "A vaccine consisting of autologous cancer cells modified with the hapten, Dinitrophenyl. The treatment program consists of multiple intradermal injections of irradiated DNP-modified autologous tumor cells mixed with bacillus Calmette-Guerin." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:/9400626", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5537" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/258" ; obo:VO_0001818 "5537" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous Dinitrophenyl Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007291 obo:IAO_0000115 "A cancer vaccine consisting of autologous ovarian cancer cell peptide antigens conjugated to the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of autologous dinitrophenyl-modified ovarian cancer vaccine may induce a cytotoxic T-lymphocyte (CTL) response against ovarian cancer cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5459" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/259" ; obo:VO_0001818 "5459" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous Dinitrophenyl-Modified Ovarian Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007292 obo:IAO_0000115 "A cell-based vaccine composed of autologous tumor cells with Epstein-Barr virus-transformed B-lymphoblastoid cells. Upon administration, this vaccine may stimulate a cytotoxic T cell response against tumor cells, resulting in tumor cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5118" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/260" ; obo:VO_0001818 "5118" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous EBV-Transformed B Lymphoblastoid-Tumor Fusion Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007293 obo:IAO_0000115 "A cell-based vaccine composed of autologous tumor cells fused with Epstein-Barr virus-transformed B-lymphoblastoid cells. Upon administration, this vaccine may stimulate a cytotoxic T cell response against tumor cells, resulting in tumor cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5225" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/261" ; obo:OGG_0000000006 "1880" ; obo:VO_0001818 "5225" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GPR183" ; rdfs:label "Autologous Epstein-Barr Virus-Transformed B-Lymphoblastoid Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007294 obo:IAO_0000115 "Multipotent self-renewing adherent non-hematopoietic stromal cells harvested from a patient's bone marrow and grown in vitro. When injected back into the patient, autologous expanded mesenchymal stem cells OTI-010 may differentiate into various mesenchyme-derived cell types and, in some instances, may augment bone marrow engraftment after whole-body irradiation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5491" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/262" ; obo:VO_0001818 "5491" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous Expanded Mesenchymal Stem Cells OTI-010 Vaccine" ; rdfs:subClassOf obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007295 obo:IAO_0000115 "An autologous tumor cell vaccine containing irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Autologous breast cancer cells are transduced ex vivo with an adenovirus vector encoding the GM-CSF gene and irradiated and then reintroduced into the patient. Upon repeated subcutaneous administration of the vaccine, autologous GM-CSF-secreting breast cancer cells secrete GM-CSF, which may stimulate a tumor-specific cytotoxic T-lymphocyte (CTL) response." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5250" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/263" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5250" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Autologous GM-CSF-Secreting Breast Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007296 obo:IAO_0000115 "A lethally irradiated, autologous colorectal cancer vaccine consisting of patient-specific colorectal cancer cells genetically modified to secrete the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Upon vaccination, the autologous GM-CSF-secreting lethally irradiated colorectal cancer cell vaccine releases GM-CSF. In turn, GM-CSF may increase the body's immune response against tumor cells by promoting the maturation and activation of dendritic cells (DCs), and enhancing tumor-specific antigen presentation to both B- and T-cells, which leads to better recognition of tumors by the immune system. In addition, GM-CSF promotes antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin-2-mediated lymphokine-activated killer cell function." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5188" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/264" ; obo:OGG_0000000006 "10232" ; obo:VO_0001818 "5188" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MSLN" ; rdfs:label "Autologous GM-CSF-secreting Lethally Irradiated Colorectal Cancer Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007297 obo:IAO_0000115 "An autologous cancer vaccine composed of lethally irradiated leukemia cells that are genetically modified to secrete the immunostimulatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF), with potential immunostimulating and antineoplastic activities. Upon intradermal injection, the autologous GM-CSF-secreting lethally irradiated leukemia cell vaccine secretes GM-CSF. In turn, GM-CSF may stimulate the immune system to attack tumor cells by enhancing the activation of dendritic cells (DCs) and promoting antigen presentation to both B- and T-lymphocytes. In addition, GM-CSF promotes antibody-dependent cellular cytotoxicity (ADCC), and increases interleukin-2-mediated lymphokine-activated killer cell function." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5240" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/265" ; obo:OGG_0000000006 "1437", "7490" ; obo:VO_0001818 "5240" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM-CSF|Gene name: WT1" ; rdfs:label "Autologous GM-CSF-Secreting Lethally Irradiated Leukemia Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007298 obo:IAO_0000115 "A recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5266" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/266" ; obo:OGG_0000000006 "3308" ; obo:VO_0001818 "5266" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HSPA4" ; rdfs:label "Autologous Heat-Shock Protein 70 Peptide Vaccine AG-858" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007299 obo:IAO_0000115 "A vaccine consisting of lethally irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous tumor DNA derived from a head and neck squamous cell carcinoma (HNSCC), with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, the autologous HNSCC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine expresses HNSCC tumor-associated antigens (TAAs), which may activate the immune system to induce a cytotoxic T-lymphocyte (CTL) response against HNSCC cells. The MRC-5 cell line, established in 1966, is a human diploid lung fibroblast cell line derived from the human lung tissue of a 14-week-old male fetus." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT02211027", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5043" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/267" ; obo:OGG_0000000006 "6375" ; obo:VO_0001818 "5043" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: XLC1" ; rdfs:label "Autologous HNSCC DNA-transfected Semi-allogeneic Fibroblasts MRC-5 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005497, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5520 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007300 obo:IAO_0000115 "A cancer vaccine consisting of autologous, B-chronic lymphocytic leukemia (B-CLL) cells harvested from a patient and transduced ex vivo with an adenoviral vector encoding the gene for the human cytokine interleukin-2 (IL-2), with potential immunostimulating and antineoplastic activities. Upon reintroduction into the patient, the autologous IL-2-expressing B-CLL vaccine expresses IL-2, stimulates natural killer (NK) cells, and may enhance the cytotoxic T-lymphocyte (CTL) immune response against the patient's B-CLL cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00458679", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5228" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/268" ; obo:OGG_0000000006 "12519", "3383", "942" ; obo:VO_0001818 "5228" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Cd80|Gene name: CD86|Gene name: ICAM1" ; rdfs:label "Autologous IL-2-expressing B-CLL Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007301 obo:IAO_0000115 "A cancer vaccine composed of tumor-specific idiotype determinants derived from an individual's tumor cells which are conjugated to keyhole limpet hemocyanin, an immunostimulant carrier protein. When injected into the individual from whom the tumor cells were isolated, this vaccine may stimulate an antitumoral cytotoxic T-lymphocytic immune response." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00104819", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5057" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/269" ; obo:OGG_0000000006 "3123" ; obo:VO_0001818 "5057" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:hasAlternativeId "VO:0007579" ; a owl:Class ; rdfs:comment "Gene name: HLA-DRB1" ; rdfs:label "Autologous Immunoglobulin Idiotype-KLH Conjugate Vaccine" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007302 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous lymphoma cells with potential immunostimulatory and antineoplastic activities. Upon intranodal administration, autologous lymphoma cell lysate-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against lymphoma cells, which may result in lymphoma cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5248" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/270" ; obo:VO_0001818 "5248" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous Lymphoma Cell Lysate-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007303 obo:IAO_0000115 "A cell-based cancer vaccine consisting of hybrid cells created by electrofusing allogeneic dendritic cells (DCs) and autologous lymphoma cells with potential immunostimulating and antitumor activities. Upon administration, autologous lymphoma cell/allogeneic dendritic cell electrofusion hybrid vaccine may stimulate the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against specific autologous lymphoma-associated antigens, resulting in lymphoma cell apoptosis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5503" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/272" ; obo:OGG_0000000006 "1638", "2315", "6490", "7299" ; obo:VO_0001818 "5503" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)|Gene name: MLANA|Gene name: DCT|Gene name: Tyrosinase" ; rdfs:label "Autologous Lymphoma Cell/Allogeneic Dendritic Cell Electrofusion Hybrid Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007304 obo:IAO_0000115 "A cell-based cancer vaccine consisting of hybrid cells created by electrofusing autologous dendritic cells (DCs) and autologous lymphoma cells with potential immunostimulating and antitumor activities. Upon administration, autologous lymphoma cell/autologous dendritic cell electrofusion hybrid vaccine may stimulate the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against specific autologous lymphoma-associated antigens, resulting in lymphoma cell apoptosis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5431" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/273" ; obo:VO_0001818 "5431" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous Lymphoma Cell/Autologous Dendritic Cell Electrofusion Hybrid Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007305 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous melanoma cells containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against melanoma cells, which may result in melanoma cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5148" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/274" ; obo:OGG_0000000006 "1485", "2315" ; obo:VO_0001818 "5148" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1|Gene name: MLANA-Dupuli" ; rdfs:label "Autologous Melanoma Lysate-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007306 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysate from autologous melanoma cells containing tumor associated antigens (TAAs) and conjugated to the immunostimulant Keyhole limpet hemocyanin (KLH), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate/KLH-pulsed autologous dendritic cell vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against melanoma cells, which may result in melanoma cell lysis. KLH is an immunogenic carrier and serves as an immunostimulant to improve antigenic immune recognition and T-cell responses and can be used to evaluate vaccine efficacy." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5213" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/275" ; obo:OGG_0000000006 "3123" ; obo:VO_0001818 "5213" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HLA-DRB1" ; rdfs:label "Autologous Melanoma Lysate/KLH-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007307 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with both a lysate from autologous melanoma cells containing tumor associated antigens (TAAs) and a synthetic peptide derived from the tumor associated antigen human cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon administration, autologous melanoma lysate/NY-ESO-1-pulsed autologous DC vaccine may stimulate the immune system to mount anti-tumoral cytotoxic T lymphocyte (CTL) and antibody-mediated immune responses against melanoma cells, which may result in melanoma cell lysis. NY-ESO-1 is expressed in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5158" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/276" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5158" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "Autologous Melanoma Lysate/NY-ESO-1-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007308 obo:IAO_0000115 "A vaccine consisting of irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous non-small cell lung cancer (NSCLC)-derived DNA with potential immunostimulatory and antineoplastic activities. Upon administration, autologous NSCLC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine expresses NSCLC tumor-associated antigens (TAAs) in addition to MHC class I-determinants and the co-stimulatory molecule B7.1, which may induce a cytotoxic T-lymphocyte (CTL) response against NSCLC cells. The MRC-5 cell line is a human diploid lung fibroblast cell line extablished in 1966." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5377" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/277" ; obo:VO_0001818 "5377" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous NSCLC DNA-Transfected Semi-Allogeneic Fibroblasts MRC-5 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007309 obo:IAO_0000115 "A personalized cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with immunogenic peptides derived from autologous non-small cell lung cancer (NSCLC) cells, with potential immunostimulating and antineoplastic activities. During leukapheresis, mature DCs are loaded with autologous NSCLC-derived peptides. Upon re-administration of the NSCLC peptide-specific DC vaccine, the immune system is exposed to NSCLC-associated antigens. This results in the induction of a specific cytotoxic T-lymphocyte (CTL) response against NSCLC cells and tumor cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5311" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/278" ; obo:VO_0001818 "5311" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous NSCLC Peptide-specific Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007310 obo:IAO_0000115 "A cancer vaccine consisting of autologous, mature monocyte-derived dendritic cells (DCs) transfected with oncofetal antigen immature laminin receptor protein (OFA-iLRP) RNA, with potential antineoplastic activity. Upon administration, DCs in the OFA-iLRP RNA-transfected autologous dendritic cell vaccine express, process, and present OFA-iLRP to the host immune system, which may mount a potent cytotoxic T-cell (CTL) response against OFA-iLRP-expressing tumor cells. As a highly conserved protein, OFA-iLRP is preferentially expressed in fetal tissues and in many types of cancer, including hematopoietic malignancies, but is not detectable in normal differentiated adult cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00715832", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5368" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/279" ; obo:OGG_0000000006 "16785" ; obo:VO_0001818 "5368" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Rspa" ; rdfs:label "Autologous OFA-iLRP RNA-Transfected Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007311 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous, irradiated dendritic cells (DCs) pulsed with ovarian tumor cell lysate containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous ovarian tumor cell lysate-pulsed dendritic cell vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against ovarian tumor cells expressing the patients ovarian tumor cell-specific TAAs, which may result in ovarian tumor cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5427" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/280" ; obo:OGG_0000000006 "5427" ; obo:VO_0001818 "5427" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Autologous Ovarian Tumor Cell Lysate-Pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007312 obo:IAO_0000115 "A specific population of autologous, pluripotent bone marrow derived cells that express high levels of the cytosolic enzyme aldehyde dehydrogenase (ALDH) with potential protective and neuro-cognition improving activity. Expression of high levels of ALDH is an indicator of the biological activity in heterogenous early stage stem cells. Upon intravenous administration, these ALDH bright cells may protect normal cells and may repair damaged cells. These cells may also protect brain cells from damage and may improve neurocognition." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5220", "https://discovery.lifemapsc.com/regenerative-medicine/cell-therapy-applications/brain-ald451-bone-marrow-derived-cells-for-malignant-glioma" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/281" ; obo:OGG_0000000006 "216", "217" ; obo:VO_0001818 "5220" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ALDH1A1|Gene name: ALDH2" ; rdfs:label "Autologous Pluripotent ALDHbr Stem Cells ALD-451 Vaccine" ; rdfs:subClassOf obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007313 obo:IAO_0000115 "A genetically-modified autologous dendritic cell-based vaccine expressing a drug-inducible costimulatory CD40 receptor (iCD40) with potential immunomodulating and antineoplastic activities. Autologous dendritic cells (DCs) are genetically modified to express the iCD40 receptor and are pulsed with the tumor antigen prostate-specific membrane antigen (PSMA). Upon intradermal administration, these DCs accumulate in local draining lymph nodes. Twenty-four hours after vaccination, the dimerizer agent AP1903 is administered; AP1903 binds to and activates iCD40 receptors presented on DC surfaces, thus activating the DCs and stimulating a cytotoxic T-lymphocyte (CTL) response against host tumor cells that express PSMA. This delayed activation strategy optimizes DC accumulation in local draining lymph nodes prior to DC activation. iCD40 contains a membrane-localized cytoplasmic CD40 domain fused to a drug-binding domain." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5282" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/282" ; obo:OGG_0000000006 "2346", "928" ; obo:VO_0001818 "5282" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD40|Gene name: Prostate" ; rdfs:label "Autologous Prostate Cancer Antigen-expressing Dendritic Cell Vaccine BPX-101" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007314 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with renal cell carcinoma (RCC) tumor cell lysate containing tumor associated antigens (TAAs) with potential immunostimulatory and antineoplastic activities. Upon administration, autologous renal cell carcinoma tumor lysate-dendritic cell vaccine may stimulate anti-tumoral cytotoxic T-lymphocyte (CTL) and antibody responses against RCC tumor cells expressing RCC TAAs, resulting in RCC tumor cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5018" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/283" ; obo:OGG_0000000006 "2315863", "7015" ; obo:VO_0001818 "5018" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Survivin|Gene name: TERT" ; rdfs:label "Autologous Renal Cell Carcinoma Tumor Lysate-Pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007315 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from sarcoma cells with potential immunostimulatory and antineoplastic activities. Upon administration, the autologous sarcoma lysate-pulsed dendritic cell vaccine exposes the immune system to an undefined amount of sarcoma-type tumor associated antigens (TAA), which may result in the induction of both specific anti-tumoral cytotoxic T lymphocytes (CTL) and antibody-dependent responses against the sarcoma TAA-expressing cells, resulting in sarcoma cell lysis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5189" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/284" ; obo:VO_0001818 "5189" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous Sarcoma Lysate-pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007316 obo:IAO_0000115 "A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with autologous T cell receptor gamma-chain alternate reading frame protein (TARP) peptide with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, autologous TARP peptide-pulsed dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against TARP-expressing cancer cells, resulting in tumor cell lysis. The highly immunogenic nuclear protein TARP is commonly expressed in breast and prostate cancer cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT02362451", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5024" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/285" ; obo:OGG_0000000006 "6862" ; obo:VO_0001818 "5024" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TBXT" ; rdfs:label "Autologous TARP Peptide-Pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007318 obo:IAO_0000115 "An autologous chronic lymphocytic leukemia cancer vaccine consisting of patient-specific membrane proteins directly extracted from patient autologous tumor cells and incorporated into liposomes along with Interleukin 2 (IL-2) to produce membrane-patched proteoliposomes, with potential immunostimulating and antineoplastic activities. After subcutaneous injection of the autologous tumor cell proteoliposomes chronic lymphocytic leukemia vaccine, liposomes deliver the encapsulated tumor antigens into the cytosol of antigen presenting cells (APCs). Subsequently, the APCs process the antigens and present antigen-derived peptides to the immune system. This may enhance recognition of tumors by the immune system, and activate both cytotoxic CD8+ T cells and CD4+ helper T cells against tumor cells. IL-2 is incorporated into the vaccine to leverage its ability to expand activated T cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5108" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/287" ; obo:OGG_0000000006 "3558" ; obo:VO_0001818 "5108" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IL2" ; rdfs:label "Autologous Tumor Cell Proteoliposome Chronic Lymphocytic Leukemia Vaccine" ; rdfs:subClassOf obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007319 obo:IAO_0000115 "A therapeutic agent produced by isolating tumor cells from an individual and processing these tumor cells into a vaccine formulation in vitro; the vaccine is then administered to the individual from whom the tumor cells were isolated. Typically combined with an adjuvant immunostimulant, an autologous cell vaccine may elicit a cytotoxic T-lymphocytic immune response to cell surface-expressed tumor-associated antigens (TAAs), resulting in tumor cell death." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:22854664", "PubMed:32558897", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5396" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/288" ; obo:OGG_0000000006 "942" ; obo:VO_0001818 "5396" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD86" ; rdfs:label "Autologous Tumor Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005427, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0050746 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007320 obo:IAO_0000115 "A dendritic cell (DC)-based cancer vaccine composed of autologous DCs pulsed with specific tumor-associated peptide antigens (TAPA), with potential immunostimulatory and antineoplastic activities. Upon administration, autologous TAPA-pulsed DC vaccine exposes the immune system to the specific TAPAs, which may result in cytotoxic T-lymphocyte (CTL)-mediated immune responses against the TAPA-expressing cancer cells. This leads to cancer cell lysis. This vaccine is specific towards peptides derived from the following proteins: sperm autoantigenic protein 17 (SP17), ropporin, A-kinase anchor protein 4 (AKAP4), pituitary tumor-transforming 1 (PTTG1) and SPANX family member B (SPANX-B)." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:18528294", "PubMed:23482679", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5035" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/289" ; obo:OGG_0000000006 "53340", "54763", "728695", "8852", "9232" ; obo:VO_0001818 "5035" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: SPA17|Gene name: ROPN1|Gene name: AKAP4|Gene name: PTTG1|Gene name: SPANXB1" ; rdfs:label "Autologous Tumor-associated Peptide Antigen-pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007321 obo:IAO_0000115 "An autologous therapeutic vaccine for the treatment of acute myelogenous leukemia. This vaccine is prepared from blood samples of patients following their first relapse. Tumor cells extracted from blood sample are modified with hapten, a process that makes the cells appear foreign to the patient's body and results in stimulating immune response against the cancer." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5404" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/290" ; obo:OGG_0000000006 "2315", "4102" ; obo:VO_0001818 "5404" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3|Gene name: MLANA" ; rdfs:label "Autologous-Cell Leukemia Vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007322 obo:IAO_0000115 "An autologous-cell vaccine for melanoma." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5110" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/291" ; obo:VO_0001818 "5110" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Autologous-Cell Melanoma Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007327 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:21036724", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5230" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/296" ; obo:VO_0001818 "5230" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "BCG, Cell Wall Skeleton Vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0005485, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007328 obo:IAO_0000115 "A vaccine consisting of replication-defective recombinant adenovirus that encodes for Bcl-Xs with potential antineoplastic activity. Vaccination with Bcl-Xs adenovirus vaccine induces apoptosis in Bcl-2 and Bcl-XL positive cancer cells, resulting in decreased tumor growth while leaving normal cells unaffected. Bcl-Xs block the function of the protooncogenes Bcl-2 and Bcl-XL which are overexpressed in a variety of solid tumors and promote cancer cell survival by inhibiting apoptosis. (NCI04)A vaccine consisting of replication-defective recombinant adenovirus that encodes for Bcl-Xs with potential antineoplastic activity. Vaccination with Bcl-Xs adenovirus vaccine induces apoptosis in Bcl-2 and Bcl-XL positive cancer cells, resulting in decreased tumor growth while leaving normal cells unaffected. Bcl-Xs block the function of the protooncogenes Bcl-2 and Bcl-XL which are overexpressed in a variety of solid tumors and promote cancer cell survival by inhibiting apoptosis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:7479929", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5399" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/297" ; obo:OGG_0000000006 "598", "7306" ; obo:VO_0001818 "5399" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:hasAlternativeId "VO:0007589" ; a owl:Class ; rdfs:comment "Gene name: BCL2L1|Gene name: TYRP1" ; rdfs:label "Bcl-Xs Adenovirus Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007329 obo:IAO_0000115 "A transforming growth factor beta2 (TGF-beta2) antisense gene-modified allogeneic tumor cell vaccine with potential immunostimulatory and antineoplastic activities. Belagenpumatucel-L is prepared by transfecting allogeneic non-small cell lung cancer (NSCLC) cells with a plasmid containing a TGF-beta2 antisense transgene, expanding the cells, and then irradiating and freezing them. Upon administration, this agent may elicit a cytotoxic T lymphocyte (CTL) response against host NSCLC cells, resulting in decreased tumor cell proliferation; vaccine immunogenicity may be potentiated by suppression of tumor TGF-beta2 production by antisense RNA expressed by the vaccine plasmid TGF-beta2 antisense transgene. Elevated levels of TGF-beta2 are frequently linked to immunosuppression in cancer patients and may be inversely correlated with prognosis in patients with NSCLC." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:26211534", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5374" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/298" ; obo:OGG_0000000006 "7042" ; obo:VO_0001818 "5374" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TGFB2" ; rdfs:label "Belagenpumatucel-L Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007330 obo:IAO_0000115 "A synthetic vaccine combining the peptide antigens of two proteins, ras oncoprotein and tumor suppressor p53" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15983396", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4992" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/299" ; obo:OGG_0000000006 "7157" ; obo:VO_0001818 "4992" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53 (P53)" ; rdfs:label "Berzofsky Ras/P53 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007331 obo:IAO_0000115 "A cancer vaccine composed of a replication-deficient, attenuated derivative of the vaccinia virus strain Ankara expressing both a CD8+ T-cell epitope from the brachyury protein and a triad of T-cell co-stimulatory molecules (MVA Brachyury-TRICOM), with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration of the brachyury-expressing modified vaccinia Ankara (MVA)-TRICOM vaccine, the expressed brachyury protein induces specific CD8+ and CD4+ T-cell responses against brachyury-expressing tumor cells. This causes both tumor cell lysis and a decrease in the growth of brachyury-expressing tumor cells. Brachyury, a member of the T-box family of transcription factors that is overexpressed in numerous cancer cell types, is correlated with increased epithelial-mesenchymal transition (EMT), cancer resistance and cancer progression. TRICOM, a triad of three human T-cell co-stimulatory molecules, B7.1, ICAM-1 and LFA-3, enhances antigen-specific T-cell activation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5439", "https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2022-05711&r=1" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/310" ; obo:OGG_0000000006 "925" ; obo:VO_0001818 "5439" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD8A" ; rdfs:label "Brachyury-expressing Modified Vaccinia Ankara-TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0000367, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007332 obo:IAO_0000115 "A cell-based cancer vaccine comprised of brain tumor initiating cells (BTICs), with potential immunostimulating and antineoplastic activity. BITCs are from the glioblastoma multiforme (GBM) cell line GBM-6 and contain glioma stem-like cell-associated antigens. Upon administration, the BITC vaccine may stimulate a specific anti-tumoral cytotoxic T-lymphocyte (CTL) response against brain tumor cancer cells and brain tumor stem like cells, resulting in tumor cell lysis. BITC have unique antigenicity and have the ability to self-renew; vaccination against BITC antigens may kill these cells and may prevent tumor recurrences." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5210" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/311" ; obo:OGG_0000000006 "3383", "941", "965" ; obo:VO_0001818 "5210" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD58|Gene name: ICAM1|Gene name: CD80" ; rdfs:label "Brain Tumor Initiating Cell Vaccine" ; rdfs:subClassOf obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007333 obo:IAO_0000115 "A cancer vaccine consisting of recombinant modified vaccinia Ankara (rMVA) encoding the prostate specific antigen (PSA), the prostate-specific membrane antigen (PSMA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). Vaccination with PSA/PSMA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells over-expressing PSA or PSMA." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCI: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C29561", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5309" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/312" ; obo:VO_0001818 "5309" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "rMVA-PSA/PSMA/TRICOM vaccine" ; rdfs:subClassOf obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007334 obo:IAO_0000115 "A vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) that encodes the gene for human interleukin-12 (hIL-12). Produced mainly by B-cells, IL-12 is an endogenous cytokine that activates natural killer (NK) cells, promotes cytotoxic T lymphocyte (CTL) responses, induces the release of interferon-gamma (IFN-gamma), and may exhibit antitumor and anti-angiogenic effects. Vaccination with canarypox-hIL-12 melanoma vaccine may stimulate the host immune system to mount an immune response against tumor cells, thereby inhibiting tumor growth and/or metastasis." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5544" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/313" ; obo:OGG_0000000006 "2521" ; obo:VO_0001818 "5544" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: FUS" ; rdfs:label "Canarypox-hIL-12 Melanoma Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007349 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:/7629885", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5329" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/372" ; obo:VO_0001818 "5329" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "CAP-2 (CEA Peptide 9-mer) Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007350 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5380", "https://link.springer.com/article/10.1007/s11888-014-0250-5" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/373" ; obo:VO_0001818 "5380" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "CAP-3 (CEA Peptide 9-mer) Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007351 obo:IAO_0000115 "9-residue human leukocyte antigen (HLA)-restricted fragment of carcinoembryonic antigen (CEA). Vaccination with carcinoembryonic antigen peptide 1-6D, which has the amino acid sequence YLSGANLNL, may elicit a cytotoxic T lymphocyte (CTL) immune response against tumors expressing CEA." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00203892", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5356" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/374" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5356" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "Carcinoembryonic Antigen Peptide 1-6D Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005430, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007352 obo:IAO_0000115 "A cancer vaccine, consisting of alphavirus vector-derived virus-like replicon particles expressing the 9-amino-acid carcinoembryonic antigen peptide (CAP) 1-6D, with potential antineoplastic activity. Vaccination with this agent may elicit a cytotoxic T lymphocyte (CTL) immune response against CEA-expressing tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:22630596", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5129" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/375" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5129" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "Carcinoembryonic Antigen Peptide 1-6D Virus-Like Replicon Particles Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007353 obo:IAO_0000115 "A cancer vaccine comprised of an epitope from the Carcinoembryonic Antigen obtained from cancer cells that can stimulate an immune response against tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:22630596", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5209" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/376" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5209" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "Carcinoembryonic Antigen Peptide-1 Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007354 obo:IAO_0000115 "A vaccine comprised of autologous dendritic cells pulsed with mRNA-encoded Carcinoembryonic Antigen (CEA) targeting tumor cells expressing CEA. " ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:21187495", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5041" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/377" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5041" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "Carcinoembryonic Antigen RNA-pulsed DC Cancer Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007356 obo:IAO_0000115 "A plasmid DNA vaccine containing the mammalian expression vector pUMVC3 (pNGVL3) encoding epitopes of CD105 (Endoglin), Y-box binding protein 1 (Yb-1), SRY-box 2 (SOX2), cadherin 3 (CDH3), and murine double minute 2 (MDM2) proteins, with potential immunomodulating and antineoplastic activities. Upon intradermal administration of pUMVC3-CD105/Yb-1/SOX2/CDH3/MDM2-epitopes plasmid DNA vaccine, the plasmid transfects cells and the peptides are expressed. This generates a specific memory Th1 (T-helper) cell immune response, stimulates secretion of cytokines by the T cells and leads to a cytotoxic T-lymphocyte (CTL) response against CD105/Yb-1/SOX2/CDH3/MDM2-expressing tumor cells. CD105/Yb-1/SOX2/CDH3/MDM2 proteins are highly immunogenic tumor associated antigens that are overexpressed in breast cancer. Additionally, these antigens are associated with breast cancer stem cells and with epithelial to mesenchymal transformation (EMT)." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5193" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/379" ; obo:OGG_0000000006 "1001", "2022", "4193", "4904", "6657" ; obo:VO_0001818 "5193" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ENG|Gene name: YBX1|Gene name: SOX2|Gene name: CDH3|Gene name: MDM2" ; rdfs:label "CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007357 obo:IAO_0000115 "A cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted peptides derived from the CD133 antigen, with potential antineoplastic activity. Upon intradermal administration, the CD133 antigen peptide-pulsed autologous DC vaccine may stimulate an anti-tumoral cytotoxic T-lymphocyte (CTL) response against CD133-expressing tumor cells, resulting in tumor cell lysis. CD133, a cancer stem cell marker, is expressed on hematopoietic stem and progenitor cells and overexpressed on many types of cancer cells; it is associated with resistance to chemotherapy and increased cancer survival. HLA-A2 is an MHC class I molecule that presents antigenic peptides to CD8+ T-cells. Epitope design that is restricted to those epitopes that bind most efficiently to HLA-A2 may improve antigenic peptide immunogenicity." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT02049489", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5107" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/380" ; obo:OGG_0000000006 "8842" ; obo:VO_0001818 "5107" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PROM1" ; rdfs:label "CD133 Antigen Peptide-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007358 obo:IAO_0000115 "A vaccine comprised of CD80-transfected allogenic breast cancer cells to induce T-cell response." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5476" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/381" ; obo:OGG_0000000006 "2064", "941" ; obo:VO_0001818 "5476" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:hasAlternativeId "VO:0007592" ; a owl:Class ; rdfs:comment "Gene name: CD80|Gene name: ERBB2" ; rdfs:label "CD80 Breast Cancer Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007359 obo:IAO_0000115 "Autologous human dendritic cells pulsed with RNA encoding the carcinoembryonic antigen (CEA) are being studied for possible use in the treatment of cancer expressing CEA." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:21187495", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5045" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/382" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5045" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "CEA RNA-pulsed Autologous Human Cultured Dendritic Cells Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007360 obo:IAO_0000115 "A plasmid vaccine encoding wild type human carcinoembryonic antigen (CEA) fused to a tetanus toxoid T helper epitope, with potential antineoplastic activity. Upon vaccination and subsequent intradermal electroporation, CEA/tetanus toxoid T helper epitope fusion protein-expressing DNA plasmid vaccine may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells. CEA, a tumor associated antigen, is overexpressed in a variety of cancer cell types. The tetanus toxoid helper peptide epitope, obtained from the bacterial Clostridium tetani toxoid, binds to class II MHC molecules and increases the helper T-cell response thereby inducing an increased and long-term immune response." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5367" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/383" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5367" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "CEA/Tetanus Toxoid T Helper Epitope Fusion Protein-Expressing DNA Plasmid Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0007361 obo:IAO_0000115 "A complex, replication-selective, E1B and partial E3 gene deleted, adenovirus type 11p (Ad11p)/Ad3 chimeric oncolytic virus with potential antineoplastic activity. Upon intralesional injection of enadenotucirev, the adenovirus selectively and rapidly replicates in cancer cells; however, it is unable to replicate in normal, healthy cells. This induces a selective adenovirus-mediated cytotoxicity in cancer cells, which leads to cancer cell lysis. Following the lysis of infected cells, the replicated virus is released and can infect adjacent cells, which both induces further tumor cell oncolysis and may activate the immune system to kill the infected tumor cells. The E1B protein causes p53 inactivation in host cells, which promotes viral replication. Deletion of E1B prevents replication in normal, healthy cells that express wild-type p53. The mutation and subsequent inactivation of p53 in cancer cells enables the E1B-deleted adenovirus to selectively replicate in cancer cells. Partial deletion of the E3 gene, which encodes the adenovirus death protein, enhances the safety profile of the administered adenovirus." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5316", "https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(05)00564-2" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/384" ; obo:VO_0001818 "5316" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Chimeric Ad11p/Ad3 Oncolytic Virus Vaccine" ; rdfs:subClassOf obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007362 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with the human cytomegalovirus (CMV) phosphoprotein pp65, with potential immunostimulatory and antineoplastic activities. Upon administration, the CMV pp65 peptide-pulsed autologous DC vaccine exposes the immune system to the CMV pp65 peptide, which may result in a cytotoxic T-lymphocyte (CTL) response against CMV pp65-expressing tumor cells leading to cell lysis. The CMV pp65 protein, also called the 65 kDa lower matrix phosphoprotein, is the primary component of the enveloped subviral particle of CMV and is expressed in certain tumor types, such as glioblastoma" ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4985", "https://academic.oup.com/neuro-oncology/article/22/Supplement_3/iii306/6018727" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/385" ; obo:OGG_0000000006 "3077579" ; obo:VO_0001818 "4985" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: UL83" ; rdfs:label "CMV pp65 Peptide-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007363 obo:IAO_0000115 "A poloxamer-formulated, bivalent DNA vaccine containing two plasmids encoding both the human cytomegaloviral (CMV) tegument phosphoprotein 65 (pp65), a major internal matrix protein, and glycoprotein B (gB), an important CMV component responsible for attachment and entry into cells, with potential immunostimulatory properties. Upon intramuscular injection of CMVpp65/gB plasmid vaccine ASP0113, the expressed proteins may activate the immune system to mount both cellular and humoral immune responses against CMV-positive cells. This results in cell lysis of CMV-infected cells and prevents both viral replication and the development of CMV disease. This vaccine also provides active immunization and protective immunity against CMV infection in CMV-negative patients exposed to infected donor cells or tissues in transplant recipients. CMV infection can cause serious complications in patients receiving either allogeneic hematopoietic cell transplants (HCT) or solid organ transplants. The poloxamer-based delivery system enhances DNA delivery." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5306" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/386" ; obo:OGG_0000000006 "3077579" ; obo:VO_0001818 "5306" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: UL83" ; rdfs:label "CMVpp65/gB Plasmid Vaccine ASP0113" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007365 obo:IAO_0000115 "A vaccine composed of synthetic peptides derived from beta-human chorionic gonadotropin (hCG) conjugated to diphtheria toxoid. Vaccination with this peptide may elicit the host immune response against hCG-producing cancer cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:/9815634", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5372" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/389" ; obo:OGG_0000000006 "11716682" ; obo:VO_0001818 "5372" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: tox1" ; rdfs:label "CTP-37-DT Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007366 obo:IAO_0000115 "A cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with cyclin B1 peptide, with potential immunostimulatory and antineoplastic activities. Upon administration, cyclin B1 peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and anti-cyclin B1 antibody responses against cyclin B1-expressing cancer cells, resulting in tumor cell lysis. Cyclin B1, a key regulator of the cell cycle and cell division, is overexpressed in a variety of cancer cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT01398124", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5139" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/390" ; obo:OGG_0000000006 "931" ; obo:VO_0001818 "5139" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MS4A1" ; rdfs:label "Cyclin B1 Peptide-pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007367 obo:IAO_0000115 "A preparation of autologous lymphocytes with potential immunopotentiating and antineoplastic activities. Cytokine-induced killer (CIK) cells are CD3- and CD56-positive, non-major histocompatibility complex (MHC)-restricted, natural killer (NK)-like T lymphocytes, generated ex-vivo by incubation of peripheral blood lymphocytes (PBLs) with anti-CD3 monoclonal antibody, interleukin (IL)-2, IL-1, and interferon gamma (IFN-gamma) and then expanded. When reintroduced back to patients after autologous stem cell transplantation, CIK cells may recognize and kill tumor cells associated with minimal residual disease (MRD). CIK cells may have enhanced cytotoxic activity compared to lymphokine-activated killer (LAK) cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:23210562", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5070" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/391" ; obo:OGG_0000000006 "174" ; obo:VO_0001818 "5070" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: AFP" ; rdfs:label "Cytokine-Induced Killer Cells Vaccine" ; rdfs:subClassOf obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007368 obo:IAO_0000115 "A vaccine composed of dendritic cells pulsed with tumor cells lysates that stimulate a potent and specific cell mediated anti-tumor immune response." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:15256471", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5163" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/392" ; obo:VO_0001818 "5163" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Dendritic Cell Tumor Cell Lysate Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007369 obo:IAO_0000115 "A cancer vaccine consisting of lymphocytes harvested from a patient with lung cancer and induced to become antigen-presenting cells (APCs) known as dendritic cells. The dendritic cells are transduced with the gene encoding an antigen specific to the patient's cancer and then returned to the patient. In the host, the altered cells stimulate the immune system to mount a primary T cell response against lung tumor cells expressing the target antigen. Dendritic cell-autologous lung tumor vaccines have been investigated for use in cancer immunotherapy." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5161" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/393" ; obo:VO_0001818 "5161" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Dendritic Cell-Autologous Lung Tumor Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007370 obo:IAO_0000115 "A cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced with a peptide fragment of carcinoembryonic antigen (CEA), a tumor-associated antigen expressed by a wide range of cancers. When the altered dendritic cells are returned to the patient, they may stimulate the host immune system to mount a cytotoxic T-lymphocyte immune response against tumor cells expressing CEA." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:21187495", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5417" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/394" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5417" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5 (CEA)" ; rdfs:label "Dendritic Cell-CEA Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007371 obo:IAO_0000115 "An autologous dendritic cells vaccine with antineoplastic property. Dendritic cells harvested from cancer patients are pulsed with human gp100 melanoma antigen and MART-1 (melanoma antigen recognized by T-cells) antigen; both antigens are up-regulated in melanomas. Vaccination with this vaccine may elicit the host immune response against MART-1 or gp100 expressing cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5067" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/395" ; obo:OGG_0000000006 "2315", "6490" ; obo:VO_0001818 "5067" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 (PMEL)|Gene name: MLANA" ; rdfs:label "Dendritic Cell-gp100-MART-1 Antigen Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007372 obo:IAO_0000115 "A cancer vaccine consisting of dendritic cells harvested from a patient with cancer and pulsed or transduced with a peptide fragment of MART-1 (melanoma antigen recognized by T-cells), an antigen expressed by melanoma cells. When the altered dendritic cells are returned to the patient, they stimulate the host immune system to mount a cytotoxic T-lymphocyte immune response against tumor cells expressing MART-1." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5524" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/396" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5524" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MLANA" ; rdfs:label "Dendritic Cell-MART-1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007373 obo:IAO_0000115 "A vaccine comprised of autologous dendritic cells pulsed with a recombinant prostate specific membrane antigen." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5000" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/397" ; obo:OGG_0000000006 "2346" ; obo:VO_0001818 "5000" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Prostate-specific membrane antigen gene engineering:" ; rdfs:label "Dendritic Cell-Recombinant Prostate-Specific Membrane Antigen Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007374 obo:IAO_0000115 "An engineered lentiviral vector targeting dendritic cells (DCs) and containing nucleic acids encoding for the human tumor-associated cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, the DC-targeting lentiviral vector ID-LV305 targets and binds to dermal DCs via the DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) receptor. Upon internalization of the vector, the NY-ESO-1 protein is expressed, stimulates DC maturation and activates the immune system to mount a cytotoxic T-lymphocyte (CTL) response against NY-ESO-1-expressing cells, which may result in tumor cell lysis. NY-ESO-1 is expressed in normal testes and on the surfaces of various tumor cells, and plays a key role in tumor cell proliferation and survival." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5493", "https://www.cancer.gov/about-cancer/treatment/clinical-trials/search/v?id=NCI-2018-00926&r=1" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/398" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5493" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "Dendritic Cell-targeting Lentiviral Vector ID-LV305 Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007375 obo:IAO_0000115 "A cancer vaccine consisting of autologous renal cell carcinoma (RCC) tumor cells modified with the hapten 2,4-dinitrophenol (DNP) with potential immunostimulating and antineoplastic activities. Administration of DNP-modified autologous renal cell carcinoma tumor cell vaccine may induce a cytotoxic T-lymphocyte (CTL) response against renal cell carcinoma tumor cells. DNP conjugation may enhance the immunogenicity of weakly immunogenic antigens." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5338" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/400" ; obo:VO_0001818 "5338" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Dinitrophenyl-Modified Autologous Renal Cell Carcinoma Tumor cell Vaccine" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007376 obo:IAO_0000115 "A plasmid DNA vaccine encoding the human pro-inflammatory cytokine interleukin-12 (IL-12) with potential immunoactivating activity. Upon intramuscular delivery by electroporation of DNA plasmid encoding interleukin-12 INO-9012, IL-12 is translated in cells and activates the immune system by promoting the activation of natural killer cells (NK cells), inducing secretion of interferon-gamma and promoting cytotoxic T-cell responses against tumor cells. This may result in both immune-mediated tumor cell death and the inhibition of tumor cell proliferation." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5016", "https://jitc.bmj.com/content/9/7/e003019" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/401" ; obo:OGG_0000000006 "2902" ; obo:VO_0001818 "5016" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GRIN1" ; rdfs:label "DNA Plasmid Encoding Interleukin-12 INO-9012 Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007377 obo:IAO_0000115 "A DNA-based combination immunotherapeutic, INO-3112, composed of VGX-3100, a preparation of DNA plasmids encoding the E6 and E7 genes of human papillomavirus (HPV) subtypes 16 and 18, combined with INO-9012, a DNA plasmid encoding the immune activator and pro-inflammatory cytokine human interleukin-12 (IL-12) with potential immunoactivating and antineoplastic activities. Upon intramuscular delivery by electroporation of VGX-3100, the HPV E6 and E7 proteins are translated in cells and elicit a cytotoxic T-lymphocyte (CTL) response against cancer cells expressing the E6 and E7 antigens, resulting in tumor cell lysis. HPV type 16 and HPV type 18 are associated with the development of certain types of cancer. Upon intramuscular delivery by electroporation of INO-9012, IL-12 is expressed and activates the immune system by promoting the activation of natural killer cells (NK cells), inducing secretion of interferon-gamma (IFN-g) and promoting CTL responses against tumor cells. This boosts the immune response and results in increased CTL-mediated tumor cell death as compared with the administration of VGX-3100 alone." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT03439085", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5136" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/402" ; obo:OGG_0000000006 "1489078", "1489079" ; obo:VO_0001818 "5136" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7|Gene name: E6" ; rdfs:label "DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007378 obo:IAO_0000115 "A therapeutic DNA vaccine composed of three parts, one encodes the E6/E7 fusion protein of human papillomavirus (HPV) type 16 (HPV16), the second is a dimerization entity and the third part encodes a protein that specifically binds to antigen presenting cells (APCs), with potential immunostimulating and antineoplastic activities. Upon intramuscular administration, the DNA vaccine VB10.16 expresses HPV16 E6/7 and a protein that targets receptors on APCs. Upon binding to APCs and subsequent internalization, the APCs mature and the HPV16 E6/7 antigenic protein is presented by the APCs. This attracts and stimulates B-lymphocytes, CD4-positive T-lymphocytes and elicits a cytotoxic T-lymphocyte (CTL) response against cancer cells expressing HPV16-associated E6 and E7 oncoproteins, which result in tumor cell lysis. HPV16 E6/7, a viral antigen, plays a key role in the development of certain types of cancer." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:36129459", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5207" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/403" ; obo:OGG_0000000006 "1489078", "1489079" ; obo:VO_0001818 "5207" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7|Gene name: E6" ; rdfs:label "DNA Vaccine VB10.16" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007379 obo:IAO_0000115 "A cancer vaccine consisting of a DNA plasmid encoding epitopes of the human preferential antigen of melanoma (PRAME) and the prostate specific membrane antigen (PSMA) with potential immunostimulating activity. Upon direct administration of this vaccine into lymph nodes, peptides expressed by DNA plasmid vector pPRA-PSM may activate the immune system, resulting in a cytotoxic T-lymphocyte (CTL) response against PRAME- and PSMA-expressing cells. PRAME and PSMA are tumor associated antigens upregulated in a number of cancer cell types. As part of the MKC1106-PP regimen exploiting the 'prime-boost strategy', this plasmid is responsible for priming the immune response and is used in conjunction with a peptide vaccine consisting of PRAME and PSMA that boosts the immune system against PRAME- and PSMA-expressing tumor cells." ; obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "NCT: https://clinicaltrials.gov/ct2/show/NCT00423254", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5407" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/404" ; obo:OGG_0000000006 "2346" ; obo:VO_0001818 "5407" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: Prostate-specific membrane antigen" ; rdfs:label "DNA Vector pPRA-PSM Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007380 obo:IAO_0000115 "A cancer vaccine comprised of a recombinant fowlpox viral vector encoding the carcinoembryonic antigen (CEA), MUC-1, a transmembrane glycoprotein secreted by glandular epithelial tissues, and TRICOM, comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3). This agent may enhance CEA and MUC-1 presentation to antigen-presenting cells (APC) and may activate a cytotoxic T-cell response against CEA- and MUC-1-expressing tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5378" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/126" ; obo:OGG_0000000006 " 4582", "1048" ; obo:VO_0001818 "5378" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5|Gene name: MUC1" ; rdfs:label "Falimarev vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007381 obo:IAO_0000115 "A therapeutic cancer vaccine containing a truncated, synthetic peptide mimic of the human angiogenic activator vascular endothelial growth factor (VEGF), consisting of 79 amino acids (amino acids 26-104 of VEGF), and emulsified in the immunoadjuvant RFASE, with potential immunostimulatory and antitumor activities. Upon intramuscular vaccination, the hVEGF26-104 moiety of hVEGF26-104/RFASE acts as an antigen and induces an immune response against VEGF, which results in anti-VEGF antibody binding to and neutralization of endogenous VEGF. This prevents the binding of endogenous VEGF to the VEGF receptor (VEGFR) and blocks VEGFR-mediated endothelial cell signaling, resulting in an inhibition of both angiogenesis and tumor cell proliferation. VEGF plays a key role in angiogenesis, tumor cell proliferation and invasion. RFASE, which belongs to the group of sulpholipopolysaccharides (SLPs), is a synthetic polysaccharide covalently coupled to lipid groups and sulphate groups, and is able to induce a strong humoral immune response upon antigen administration." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5090" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/456" ; obo:OGG_0000000006 "7422" ; obo:VO_0001818 "5090" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VEGFA" ; rdfs:label "hVEGF26-104/RFASE Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007382 obo:IAO_0000115 "A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus subtype 6 (HPV-6), with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV-6-targeting immunotherapeutic vaccine INO-3106 expresses the HPV-6 E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against tumor cells that are expressing those proteins, resulting in tumor cell lysis. HPV-6 infections are associated with aerodigestive malignancies." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5464" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/438" ; obo:OGG_0000000006 "2829163" ; obo:VO_0001818 "5464" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HPV6 E6" ; rdfs:label "HPV-6-targeting Immunotherapeutic Vaccine INO-3106" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007383 obo:IAO_0000115 "A liposome-encapsulated peptide vaccine consisting of a synthetic peptide derived from the mucin 1 (MUC-1) antigen with potential antineoplastic activity. Upon vaccination, MUC-1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against MUC-1-expressing tumor cells, resulting in growth inhibition. MUC-1 antigen is a high-molecular-weight transmembrane glycoprotein that is overexpressed on the cell surfaces of many epithelial tumor cells as well as on the cell surfaces of some B-cell lymphoma cells and multiple myeloma cells. (NCIT_C2195)." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5103" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/65" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5103" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "Emepepimut-S Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007384 obo:IAO_0000115 "An allogeneic urothelial bladder cancer cell vaccine expressing a recombinant secretory form of the immunoadjuvant heat shock protein gp96 fused with an immunoglobulin Fc domain (gp96-Ig) protein, with potential antineoplastic activity. Upon administration of the gp96-Ig-secreting allogeneic bladder cancer cell vaccine HS-410, the live, irradiated tumor cells continuously secrete gp96-Ig along with its chaperoned tumor associated antigens (TAAs). This enhances antigen cross presentation to cytotoxic T-lymphocytes (CTLs) and, upon expansion, leads to the induction of a potent CTL response against the TAAs on the endogenous bladder cancer cells. This vaccine also induces a memory T cell response that could fight recurring cancer cells. gp96-Ig is constructed by replacing the KDEL endoplasmic reticulum (ER) retention sequence of gp96 with the Fc portion of the IgG1 protein. This allows for gp96, normally an ER-resident chaperone peptide, to be released from cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5033" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/209" ; obo:OGG_0000000006 "7184" ; obo:VO_0001818 "5033" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HSP90B1" ; rdfs:label "gp96-secreting Allogeneic Bladder Cancer Cell Vaccine HS-410" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007385 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant fowlpox virus vector encoding an immunogenic peptide derived from the cancer-testis antigen NY-ESO-1, an antigen found in normal testis and various tumors, including bladder, breast, hepatocellular, melanoma, and prostate cancers. Vaccination with NY-ESO-1 peptide vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5300" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/131" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5300" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "Fowlpox-NY-ESO-1 Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005425, obo:VO_0005484, obo:VO_0005485, obo:VO_0005499, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_684 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007386 obo:IAO_0000115 "A cancer vaccine comprised of autologous dendritic cells pulsed with synthetic glioma-associated antigen (GAA) peptides with potential antineoplastic activity. Upon administration, this vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against GAA peptide-expressing glioma cells, resulting in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5096" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/137" ; obo:OGG_0000000006 "2548" ; obo:VO_0001818 "5096" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GAA " ; rdfs:label "Glioma-Associated Antigen Peptide-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007387 obo:IAO_0000115 "A cell-based cancer vaccine comprised of dendritic cells (DCs) pulsed with various, synthetic glioma-associated antigen (GAA) peptides, with potential antineoplastic activity. Upon subcutaneous administration, the glioma-associated peptide-loaded DC vaccine SL-701 exposes the immune system to various GAA peptides. This may stimulate both anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against the GAA-expressing glioma cells, which may result in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5073" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/138" ; obo:OGG_0000000006 "1956" ; obo:VO_0001818 "5073" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: EGFR" ; rdfs:label "Glioma-associated Peptide-loaded Dendritic Cell Vaccine SL-701" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007388 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5202" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/426" ; obo:OGG_0000000006 "55553" ; obo:VO_0001818 "5202" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: SOX6" ; rdfs:label "HLA-A2-Restricted Synthetic Glioma Antigen Peptides Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007389 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5298" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/458" ; obo:OGG_0000000006 "3417" ; obo:VO_0001818 "5298" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IDH1" ; rdfs:label "IDH1R132H Mutation-targeting IDH1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007390 obo:IAO_0000115 "A peptide vaccine consisting of a peptide derived from isocitrate dehydrogenase 1 (IDH1) containing the point mutation R132H (IDH1R132H), with potential antineoplastic activity. Intradermal vaccination with the IDH1R132H-specific peptide vaccine PEPIDH1M may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells that express the IDH1R132H protein. The IDH1 point mutation of amino acid residue 132 is highly expressed in gliomas and is associated with increased production of the oncometabolite R-2-hydroxyglutarate" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5461" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/459" ; obo:OGG_0000000006 "3417" ; obo:VO_0001818 "5461" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IDH1" ; rdfs:label "IDH1R132H-Specific Peptide Vaccine PEPIDH1M" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007391 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from malignant glioma cells with potential immunostimulatory and antineoplastic activities. Upon administration, malignant glioma tumor lysate-pulsed autologous dendritic cell vaccine exposes the immune system to undefined malignant glioma tumor-associated antigens (TAAs), which may result in anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against glioma cells and glioma cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5215" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/494" ; obo:OGG_0000000006 "4100", "6490" ; obo:VO_0001818 "5215" ; a owl:Class ; rdfs:comment "Gene name: MAGEA1|Gene name: gp100" ; rdfs:label "Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ] . obo:VO_0007392 obo:IAO_0000115 "An antineoplastic vaccine directed against a peptide found in the epidermal growth factor receptor class III variant (EGFRvIII), a constitutively activated mutant of the wild-type tyrosine kinase. This protein variant is present in a substantial proportion of malignant gliomas and other human cancers." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5531" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/64" ; obo:OGG_0000000006 "1100818972" ; obo:VO_0001818 "5531" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: EGFR" ; rdfs:label "EGFRvIII Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007393 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5151" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/127" ; obo:VO_0001818 "5151" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Fas-Chimera Transgene-expressing Endothelial Tumor Cell-targeting Adenovector VB-111 Vaccine" ; rdfs:subClassOf obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007394 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with purified peptides derived from the tumor-associated antigen (TAA) CD133, with potential immunostimulatory and antineoplastic activities. Upon leukapheresis, monocytes are differentiated into DCs and are mixed with the CD133 peptides. Upon intradermal re-administration of the ICT-121 DC vaccine, the DCs present the CD133 peptides to the immune system, which stimulates the immune system to induce a specific cytotoxic T-lymphocyte (CTL) response against CD133-expressing tumor cells and leads to tumor cell lysis. CD133 is overexpressed on various types of cancer cells; its overexpression is correlated with increased resistance to chemotherapy." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5277" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/457" ; obo:OGG_0000000006 "8842" ; obo:VO_0001818 "5277" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PROM1" ; rdfs:label "ICT-121 Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007395 obo:IAO_0000115 "A multivalent vaccine againt breast cancer that comprised of the epitope antigens of Globo H hexasaccharide 1 (Globo H), GM2 ganglioside, Lewis-Y, MUC1-32(aa), TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin, with potential antineoplastic activity. The antigens included in this vaccine are associated various cancer cells. Vaccination with this multivalent vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5229" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/174" ; obo:OGG_0000000006 " 4582", "2760" ; obo:VO_0001818 "5229" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM2A|Gene name: MUC1" ; rdfs:label "Globo-H-GM2-Lewis-y-MUC1-32(aa)-sTn(c)-TF(c)-Tn(c)-KLH Conjugate Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007396 obo:IAO_0000115 "A dendritic cell (DC)-based cancer vaccine composed of autologous, type-1 polarized dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted HER-2-derived peptides, with potential immunomodulatory and antineoplastic activities. Autologous DCs were treated with GM-CSF, interleukin-4, interferon-gamma and bacterial lipopolysaccharide (LPS), a toll-like receptor type 4 agonist, to produce highly polarized DCs (alphaDC1) that are capable of producing high levels of interleukin-12p70 (IL-12p70). Upon administration, HER2-pulsed autologous DC vaccine may stimulate a potent cytotoxic T-lymphocyte (CTL) response against HER-2-positive tumor cells, which may result in tumor cell death and decreased tumor growth. HER-2, a tyrosine kinase receptor for epidermal growth factor (EGF) (also known as neu and ErbB2), is overexpressed by a variety of cancers." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5237" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/306" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5237" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "HER2-pulsed Autologous Type-1 Polarized Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007397 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4997" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/447" ; obo:OGG_0000000006 "1442", "7494" ; obo:VO_0001818 "4997" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: XBP1|Gene name: CSH1" ; rdfs:label "hTERT/Survivin/CMV Multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007398 obo:IAO_0000115 "A cancer vaccine containing a plasmid encoding the mammaglobin-A gene with potential immunostimulating and antineoplastic activities. Upon administration, mammaglobin-A DNA vaccine may induce both humoral and cytotoxic T lymphocyte (CTL) immune responses against tumor cells that express mammaglobin-A, which may result in decreased tumor growth. The 10 kiloDalton (kD) glycoprotein mammglobin-A is expressed in over 80% of human breast cancers." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5166" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/495" ; obo:OGG_0000000006 "4582", "634" ; obo:VO_0001818 "5166" ; a owl:Class ; rdfs:comment "Gene name: CEACAM1|Gene name: MUC1" ; rdfs:label "Mammaglobin-A DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ] . obo:VO_0007399 obo:IAO_0000115 "A cancer vaccine consisting of a proprietary, recombinant modified vaccinia Ankara (MVA) viral vector encoding an epitope of human epidermal growth factor receptor 2 (HER2) with potential antineoplastic activity. Upon administration, modified vaccinia Ankara (Bavarian Nordic)-HER2 vaccine may stimulate the host immune system to mount humoral and cytotoxic T lymphocyte responses against HER2-expressing tumor cells, resulting in tumor cell lysis. HER2, also known as ErbB-2, is a tyrosine kinase growth factor receptor and a member of the epidermal growth factor receptor family; it plays a significant role in the pathogenesis of some breast cancers" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5036" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/530" ; obo:OGG_0000000006 "2064", "2315" ; obo:VO_0001818 "5036" ; a owl:Class ; rdfs:comment "Gene name: MLANA-Dupli|Gene name: ERBB2" ; rdfs:label "Modified Vaccinia Ankara (Bavarian Nordic)-HER2 Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ] . obo:VO_0007401 obo:IAO_0000115 "A proprietary lipid emulsion containing five vaccines: diphtheria, pertussis, tetanus (DPT), Bacille Calmette-Guerin (BCG), measles, Serratia marcescens and pneumococcal, with potential immunostimulating activity. Subcutaneous administration of the DPT/BCG/measles/Serratia/pneumococcus vaccine activates the immune system and may both abrogate tumor-induced immune tolerance and induce an antitumor immune response, which may eradicate the tumor. (NCIT_C62801)." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4987" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/51" ; obo:VO_0001818 "4987" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "E1M(184V) Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007402 obo:IAO_0000115 "A cancer vaccine containing autologous dendritic cells (DCs) that are pulsed with mRNA encoding human telomerase reverse transcriptase (hTERT) and survivin peptide, with potential immunostimulatory and antineoplastic activities. Upon administration, hTERT mRNA/survivin peptide-double-loaded autologous dendritic cell vaccine may elicit an immune response against cancer cells expressing hTERT and survivin by activating cytotoxic T-cells (CTLs), natural killer cells (NKs), and B-lymphocytes. The tumor associated antigens (TAAs) hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types and play key roles in tumor cell growth and survival." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5121" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/440" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5121" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "hTERT mRNA/Survivin Peptide-double-loaded Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007403 obo:IAO_0000115 "A therapeutic cancer vaccine consisting of four epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, including hTERT (540-548) acetate, hTERT (611-626) acetate, hTERT (672-686) acetate and hTERT (766-780) acetate, emulsified individually in the adjuvant montanide ISA-51 VG and administered with the immune response modifier (IRM) imiquimod, with potential immunostimulating and antineoplastic activities. Each hTERT peptide emulsion is administered individually by intradermal injection. Subsequently, imiquimod is applied topically to the injection site(s). Vaccination with GX 301 may elicit a cytotoxic T-cell (CTL) response against telomerase-expressing tumor cells. Telomerase is expressed in the majority of human cancer cells, infrequently expressed in normal cells, and is directly linked to tumorigenesis. Imiquimod stimulates cytokine production through the activation of toll-like receptor 7 (TLR-7), and also exhibits antiproliferative effects. Montanide ISA-51, also known as incomplete Freund's adjuvant (IFA), is a stabilized water-in-oil emulsion containing mineral oil with mannide oleate, which contains vegetable-grade (VG) oleic acid derived from olive oil. ISA-51 non-specifically stimulates cell-mediated immune responses to antigens." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5516" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/441" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5516" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "hTERT Multipeptide/Montanide ISA-51 VG/Imiquimod Vaccine GX 301" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007404 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5065" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/445" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5065" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "hTERT Vaccine V934/V935" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007405 obo:IAO_0000115 "A poxvirus made non-infectious by ultraviolet light or other inactivation methods in order to reduce its pathogenicity. In cancer gene therapy, inactivated vaccinia virus may be used as a vector to express a protein that kills tumor cells or elicits specific anti-tumor immunity. In a cancer vaccine application, tumor cells taken from the host may be adsorbed with inactivated vaccinia virus and returned to the host, where the modified tumor cells may stimulate an anti-tumor immune response." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5130" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/465" ; obo:VO_0001818 "5130" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Inactivated Vaccinia Virus Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007406 obo:IAO_0000115 "A cancer vaccine comprised of a recombinant vaccinia viral vector encoding the carcinoembryonic antigen (CEA), MUC-1 (mucin-1), a transmembrane glycoprotein secreted by glandular tissues, and TRICOM, comprised of the three co-stimulatory molecule transgenes B7-1, ICAM-1 and LFA-3. Upon administration, inalimarev may enhance CEA and MUC-1 presentation to antigen presenting cells (APC) and may activate a cytotoxic T lymphocyte (CTL) response against CEA- and MUC-1-expressing tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5099" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/466" ; obo:OGG_0000000006 "1048", "4582" ; obo:VO_0001818 "5099" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5|Gene name: MUC1" ; rdfs:label "Inalimarev Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007407 obo:IAO_0000115 "A proprietary, live-attenuated, double-deleted (LADD) strain of the Gram-positive bacterium Listeria monocytogenes (Lm) encoding multiple, as of yet undisclosed, tumor-associated antigens (TAAs), with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, live-attenuated double-deleted Listeria monocytogenes bacteria JNJ-64041809 is taken up by antigen-presenting cells (APCs), including dendritic cells (DCs). The TAAs are subsequently expressed by the APCs and then processed and presented to the immune system by both major histocompatibility complex (MHC) class I and II molecules. This activates the immune system and leads to the recruitment and activation of cytotoxic T-lymphocytes (CTLs) against the TAA-expressing tumor cells, eventually resulting in tumor cell lysis. Two genes contributing to the virulence of Lm have been removed to minimize the risk of infection." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5258" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/472" ; obo:VO_0001818 "5258" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Live-attenuated Double-deleted Listeria monocytogenes Bacteria JNJ-64041809 Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007408 obo:IAO_0000115 "A conjugate consisting of keyhole-limpet hemocyanin (KLH) and fluorescein isothiocyanate (FITC) with potential immunostimulating activity. Vaccination with KLH-FITC may elicit an immune response against fluorescein and the production of anti-fluorescein IgG antibodies. KLH, a natural protein isolated from the marine mollusk keyhole limpet, is an immunostimulant carrier protein." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5146" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/473" ; obo:VO_0001818 "5146" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "KLH-FITC Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007409 obo:IAO_0000115 "A cell-based vaccine targets tumors expressing the HER2/neu marker. HER-2/neu is a growth factor receptor, and its overexpression has been associated with a number of cancers including breast, ovarian, colon and lung cancers. APC8024 comprise of autologous antigen-presenting peripheral blood mononuclear cells (APCs) that have been exposed to HER2/neu protein and can be administered to the patient. These cells may stimulate an antitumor T-cell response to cancer cells expressing HER2/neu." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5538" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/475" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5538" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Lapuleucel-T Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007410 obo:IAO_0000115 "A cell-based cancer vaccine consisting of autologous dendritic cells (DCs) pulsed with mesothelioma tumor lysate with potential immunostimulating and antineoplastic activities. Upon administration, mesothelioma tumor lysate-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount a specific cytotoxic T lymphocyte (CTL) response against mesothelioma tumor cells, resulting in tumor cell lysis. " ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5187" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/525" ; obo:OGG_0000000006 "1234" ; obo:VO_0001818 "5187" ; a owl:Class ; rdfs:comment "Gene name: CCR5" ; rdfs:label "Mesothelioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007411 obo:IAO_0000115 "A cell wall fraction of bacillus Calmette-Guerin (BCG) obtained by menthol extraction with immunomodulating properties and potential use in cancer immunotherapy." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5235" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/526" ; obo:VO_0001818 "5235" ; a owl:Class ; rdfs:label "Methanol Extraction Residue of BCG" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007412 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5347" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/529" ; obo:VO_0001818 "5347" ; a owl:Class ; rdfs:comment "Gene name: P10" ; rdfs:label "Mimotope-P10s-PADRE Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007413 obo:IAO_0000115 "A vaccine consisting of a monoclonal antibody (MoAb) directed against an idiotype that mimics a human milk fat globule (HMFG) membrane epitope. Vaccination with monoclonal antibody 11D10 anti-idiotype vaccine induces anti-anti-idiotype antibodies (Ab3) that may react with breast cancer cell lines expressing the HMFG membrane epitope." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5286" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/533" ; obo:OGG_0000000006 "4240" ; obo:VO_0001818 "5286" ; a owl:Class ; rdfs:comment "Gene name: MFGE8" ; rdfs:label "Monoclonal Antibody 11D10 Anti-Idiotype Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007414 obo:IAO_0000115 "A recombinant monoclonal antibody in which the heavy and light chain variable domains mimic a specific epitope of the tumor-associated protein carcinoembryonic antigen (CEA). This agent is used as a cancer vaccine against tumors that express CEA." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5452" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/534" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5452" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5" ; rdfs:label "Monoclonal Antibody 3H1 Anti-Idiotype Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005486, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5409 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_769 ] . obo:VO_0007415 obo:IAO_0000115 "An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5308" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/536" ; obo:OGG_0000000006 "2583" ; obo:VO_0001818 "5308" ; a owl:Class ; rdfs:comment "Gene name: B4GALNT1" ; rdfs:label "Monoclonal Antibody A1G4 Anti-Idiotype Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005486, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5409 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_769 ] . obo:VO_0007416 obo:IAO_0000115 "An anti-idiotypic (anti-Id) rat monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma, and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id A1G4 MoAb may elicit cellular and humoral immune responses against GD2 expression tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5469" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/537" ; obo:OGG_0000000006 "6489" ; obo:VO_0001818 "5469" ; a owl:Class ; rdfs:comment "Gene name: ST8SIA1" ; rdfs:label "Monoclonal Antibody GD2 Anti-Idiotype Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005486, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5409 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_769 ] . obo:VO_0007417 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5239" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/538" ; obo:VO_0001818 "5239" ; a owl:Class ; rdfs:label "Montanide ISA-51/Survivin Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007418 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5362" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/544" ; obo:OGG_0000000006 "4255" ; obo:VO_0001818 "5362" ; a owl:Class ; rdfs:comment "Gene name: MGMT" ; rdfs:label "MSCV-MGMT(P140K) Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007419 obo:IAO_0000115 "A cancer vaccine comprised of a synthetic peptide derived from the mucin 1 (MUC1) antigen with potential antineoplastic activity. Upon administration, MUC1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the MUC1 antigen, resulting in decreased tumor growth. Overexpressed on many tumor cells, MUC1 antigen, a mammary-type apomucin, is a high-molecular-weight transmembrane glycoprotein." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5517" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/545" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5517" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "MUC-1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007420 obo:IAO_0000115 "A peptide vaccine containing human mucin 2 (MUC2) protein conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. MUC2, a secretory or gel forming glycoprotein expressed predominantly in goblet cells of the gastrointestinal and respiratory tracts, is overexpressed as an aberrant or deglycosylated form in various tumors such as gastric carcinomas and some hormone-refractory prostate cancers. MUC2 protein is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. Vaccination with MUC2-KLH may result in the production of antibodies as well as elicit a cytotoxic T- lymphocyte (CTL) response against tumor cells expressing MUC2" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5169" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/547" ; obo:OGG_0000000006 "4583" ; obo:VO_0001818 "5169" ; a owl:Class ; rdfs:comment "Gene name: MUC2" ; rdfs:label "MUC-2-KLH Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007421 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5123" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/548" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5123" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "MUC1 Antigen/SB AS-2 Vaccine" ; rdfs:subClassOf obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007422 obo:IAO_0000115 "A peptide vaccine, containing human tumor-associated epithelial mucin (MUC1) conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with MUC1-KLH conjugate vaccine may stimulate humoral and cytotoxic T-lymphocyte (CTL) responses against tumor cells expressing the MUC1 antigen. In this vaccine, MUC1 antigen is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in an aberrant or deglycosylated form in various cancers such as those of the breast, prostate, and ovary." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5251" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/549" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5251" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "MUC1-KLH Conjugate Vaccine" ; rdfs:subClassOf obo:VO_0005425, obo:VO_0005484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ] . obo:VO_0007423 obo:IAO_0000115 "A peptide vaccine containing the human tumor-associated antigen epithelial mucin (MUC1 antigen) conjugated with keyhole limpet hemocyanin (KLH) and combined with the nonspecific immunoadjuvant QS21, with potential antineoplastic activity. MUC1 antigen is linked with KLH, an immunostimulant and a hapten carrier, in order to enhance immune recognition; the co-administration of saponin-derived QS21 potentially amplifies the total immune response to the MUC1 antigen. Administration of MUC1-KLH vaccine/QS21 may result in both the production of antitumor antibodies and the stimulation of a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the MUC1 antigen. MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed as an aberrant or deglycosylated form in various cancers such as breast, prostate and ovarian cancers." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5160" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/550" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5160" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "MUC1-KLH Vaccine/QS21" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007424 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5068" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/551" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5068" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "MUC1-targeted Peptide GO-203-2C Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007425 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5522" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/552" ; obo:OGG_0000000006 "2348" ; obo:VO_0001818 "5522" ; a owl:Class ; rdfs:comment "Gene name: FOLR1" ; rdfs:label "Multi-epitope Folate Receptor Alpha Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ] . obo:VO_0007426 obo:IAO_0000115 "A cancer vaccine composed of a combination of the injectable formulations S-488210, which contains the three HLA-A*02:01-restricted peptides up-regulated lung cancer 10 (lymphocyte antigen 6K; LY6K; URLC10), cell division cycle-associated protein 1 (kinetochore protein Nuf2; NUF2; CDCA1) and insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3; KOC1) and S-488211, which contains the two HLA-A*02:01-restricted peptides DEP domain-containing protein 1A (DEPDC1) and M-phase phosphoprotein 1 (kinesin-like protein KIF20B; MPHOSPH1), with potential immunostimulatory and antitumor activities. Upon administration, multipeptide vaccine S-588210 may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing KOC1, CDCA1, URLC10, DEPDC1 or MPHOSPH1 peptides, resulting in tumor cell lysis and decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5064" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/556" ; obo:OGG_0000000006 "10643", "54742" ; obo:VO_0001818 "5064" ; a owl:Class ; rdfs:comment "Gene name: LY6K |Gene name: IGF2BP3" ; rdfs:label "Multipeptide Vaccine S-588210" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007427 obo:IAO_0000115 "A cancer vaccine consisting of autologous dendritic cells which have been pulsed with a mutant p53 peptide. Vaccination with mutant p53 peptide pulsed dendritic cells may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. Many tumor cells overexpress mutant p53 proteins, resulting in the loss of apoptosis regulation and abnormal cell proliferation." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5364" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/559" ; obo:VO_0001818 "5364" ; a owl:Class ; rdfs:label "Mutant p53 Peptide Pulsed Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007428 obo:IAO_0000115 "A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities. Originally developed for the eradication of smallpox, MVA is a highly attenuated and replication-defective strain incapable of virion assembly and exerts potent immunostimulatory activity against antigens. Vaccination with MVA-MUC1-IL2 vaccine may stimulate the host immune system to mount a humoral and cytotoxic T lymphocyte (CTL) responses against tumor cells expressing MUC1, a tumor associated antigen, resulting in tumor cell lysis. Expression of IL-2 augments the specific CTL response against MUC1 expressing cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5091" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/564" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5091" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "MVA-MUC1-IL2 Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007429 obo:IAO_0000115 "A combination peptide vaccine of 2 chimeric peptides of the promiscuous T cell epitope derived from measles virus fusion protein (MVF; amino acid residues 288-302) co-synthesized with B-cell epitopes derived from the HER-2/neu a.a. 597-626 and HER-2/neu a.a. 266-296, with potential antineoplastic activity. Vaccination with MVF-HER-2(597-626)/MVF-HER-2(266-296) peptide vaccine may be capable of inducing an active specific immune response, mounting a cytotoxic T-lymphocyte (CTL) response and an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells that overexpress the HER-2 protein. The oncogenic protein HER-2, a member of the human epidermal growth factor receptor (EGFR) family of tyrosine kinases, is overexpressed in a variety of cancers and is correlated with increased tumor growth, progression and a poor prognosis. HER-2(597-626) corresponds to the binding site of trastuzumab on the extracellular domain IV of HER-2; HER-2 (266-296) corresponds to the binding site of pertuzumab on the dimerization loop of domain II of HER-2" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5400" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/566" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5400" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "MVF-HER-2(597-626)/MVF-HER-2 (266-296) Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007430 obo:IAO_0000115 "A vaccine formulation consisting of several types of human papillomavirus (HPV)-derived noninfectious virus-like particles (VLPs) with potential immunoprophylactic activity. Upon administration, HPV L1 VLP vaccine V504 may generate humoral immunity against various HPV L. major capsid proteins, thereby preventing cervical infection upon exposure to the associated HPV types. VLPs are composed of self-assembling L. major capsid proteins or functional L. major capsid protein derivatives." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5449" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/450" ; obo:VO_0001818 "5449" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Human Papilloma Virus L1 Virus-Like Particle V504 Vaccine" ; rdfs:subClassOf obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007431 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5408" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/478" ; obo:OGG_0000000006 "1489079", "2829163" ; obo:VO_0001818 "5408" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: HPV6 E6|Gene name: E7" ; rdfs:label "Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_4362 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007432 obo:IAO_0000115 "A cancer vaccine consisting of a humanized monoclonal antibody that mimics a tumor-associated antigen 791Tgp72 (also known as CD55). Vaccination with this agent may stimulate a host cytotoxic T-cell response against tumor cells expressing CD55, resulting in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5195" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/532" ; obo:OGG_0000000006 "1604" ; obo:VO_0001818 "5195" ; a owl:Class ; rdfs:comment "Gene name: CD55" ; rdfs:label "Monoclonal Antibody 105AD7 Anti-idiotype Vaccine" ; rdfs:subClassOf obo:VO_0005426, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3347 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9256 ] . obo:VO_0007433 obo:IAO_0000115 "A multipeptide vaccine consisting of peptides derived from lymphocyte antigen 6 complex locus K (LY6K) and type I and II vascular endothelial growth factor receptors (VEGFRs) with potential antineoplastic activity. Upon administration, LY6K/VEGFR1/VEGFR2 multipeptide vaccine may elicit an antitumor cytotoxic T-lymphocyte (CTL) immune response against LY6K-expressing tumor cells and/or VEGFR-expressing vascular endothelial cells involved in tumor angiogenesis. LY6K is a tumor-associated antigen (TAA) that occurs singly in glycosylphosphatidyl-inositol (GPI)-linked cell-surface glycoproteins or as three-fold repeated domain in the urokinase-type plasminogen activator receptor; VEGFRs are cell surface receptors that stimulate endothelial cell proliferation, invasion, angiogenesis, and vasculogenesis upon ligand binding and receptor activation." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5164" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/486" ; obo:OGG_0000000006 "54742", "7422" ; obo:VO_0001818 "5164" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: LY6K|Gene name: VEGFA" ; rdfs:label "LY6K/VEGFR1/VEGFR2 Multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005496, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5041 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007434 obo:IAO_0000115 "A carbohydrate-based vaccine comprised of the Globo H hexasaccharide 1 (Globo H) antigen conjugated to DT-CRM197, a non-toxic, mutated form of diphtheria toxin (DT), with potential immunostimulating and antineoplastic activities. Upon administration of Globo H-DT vaccine OBI-833, the carbohydrate antigen Globo H may stimulate a cytotoxic T-lymphocyte (CTL) response against Globo H-expressing tumor cells, thereby decreasing tumor cell proliferation. The hexasaccharide Globo H is a tumor-associated antigen (TAA) commonly found on a variety of tumor cells. DT-CRM197, also called diphtheria toxin cross-reacting material 197, is used to increase the immunogenicity of the Globo H carbohydrate antigen." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5055" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/172" ; obo:OGG_0000000006 "11716682" ; obo:VO_0001818 "5055" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: tox1" ; rdfs:label "Globo H-DT Vaccine OBI-833" ; rdfs:subClassOf obo:VO_0005426, obo:VO_0005484, obo:VO_0005486, obo:VO_0005490, obo:VO_0005496, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10534 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5041 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9256 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007435 obo:IAO_0000115 "A synthetic peptide derived from the protein ESW/FLI1 type 2 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-2 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 2 fusion protein. (NCIT_C49064)." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "PubMed:/2753158", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5432" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/63" ; obo:OGG_0000000006 "297374825" ; obo:VO_0001818 "5432" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CD22" ; rdfs:label "EF-2 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3369 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007436 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with six synthetic glioblastoma (GBM) peptides: absent in melanoma 2 (AIM-2), melanoma-associated antigen 1 (MAGE-1), tyrosinase-related protein 2 (TRP-2), glycoprotein 100 (gp100), epidermal growth factor receptor 2 (HER-2), interleukin-13 receptor subunit alpha-2 (IL-13Ra2), with potential immunostimulatory and antineoplastic activities. Mononuclear cells obtained via leukapheresis are differentiated into DCs, and pulsed with the GBM-associated peptides. Upon administration, multi-glioblastoma-peptide-targeting autologous DC vaccine ICT-107 exposes the immune system to GBM-associated antigens, which activates a specific cytotoxic T-lymphocyte (CTL) response against GBM cells. This leads to GBM cell lysis. The six peptides are derived from tumor associated antigens (TAA) expressed on GBM cells and cancer stem cells (CSCs). GBM stem-like cells contain a specific range of antigens that are essential for the neoplastic growth and survival of GBM cells" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5421" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/554" ; obo:OGG_0000000006 "4100", "6490" ; obo:VO_0001818 "5421" ; a owl:Class ; rdfs:comment "Gene name: MAGEA1|Gene name: gp100" ; rdfs:label "Multi-glioblastoma-peptide-targeting Autologous Dendritic Cell Vaccine ICT-107" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3068 ] . obo:VO_0007437 obo:IAO_0000115 "A preparation of allogeneic HLA-matched leukocytes treated with a derivative of placental protein 14 (PP14) with potential immunomodulating activity. PP14 derivative-treated HLA-matched donor mononuclear cell-enriched leukocytes contain at least fifty-five percent early-apoptotic T cells; after infusion and when processed by recipient dendritic cells, early-apoptotic T cells may help induce a decrease in the donor effector T-cell responses against the recipient of an allogeneic hematopoietic stem cell (HSC) transplant, thereby minimizing allogeneic HSC transplant-related graft-versus-host disease (GVHD). PP14, a 162 amino acid glycosylated protein secreted by the late secretory phase endometrium, binds to T cells in a carbohydrate fashion and has been shown to induce T-cell apoptosis; maternal immune tolerance to the fetus and pregnancy-related remissions of autoimmune disease may involve PP14-induced T cell apoptosis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5093" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/427" ; obo:OGG_0000000006 "5047" ; obo:VO_0001818 "5093" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Gene name: PAEP" ; rdfs:label "HLA-Matched Donor Mononuclear Cell-Enriched Leukocytes Apocell vaccine" ; rdfs:subClassOf obo:VO_0000001, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0081267 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007438 obo:IAO_0000115 "Human mesenchymal stem cells (MSCs) transduced with a retroviral vector encoding a modified form of the cytokine interleukin-12 (IL-12), with potential immunomodulating and antineoplastic activities. Upon intratumoral administration, IL-12-expressing MSC vaccine GX-051 secretes IL-12. IL-12 activates the immune system by both promoting the secretion of interferon-gamma, which activates natural killer cells (NKs), and inducing cytotoxic T-cell responses, which may result in both decreased cell proliferation and increased cell death in tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5168" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/461" ; obo:VO_0001818 "5168" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "IL-12-expressing Mesenchymal Stem Cell Vaccine GX-051" ; rdfs:subClassOf obo:VO_0005497, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11934 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007439 obo:IAO_0000115 "A dendritic cell (DC)-based vaccine composed of program death ligands 1 and 2 (PDL1/L2)-silenced DCs and loaded with the recipient's minor histocompatibility antigens (MiHA), with potential use for graft-versus-tumor (GVT) induction following allogeneic stem cell transplantation (allo-SCT). Donor DCs are electroporated ex vivo with MiHA mRNA and small interfering RNAs (siRNAs) designed to silence the expression of PD L1/L2. After allo-SCT and upon intravenous administration of the MiHA-loaded PD-L1/L2-silenced DC vaccine, the DCs induce the expansion and activation of MiHA-specific CD8-positive T-cells. These tumor antigen-reactive T-cells exert their GVT effect by killing miHA-positive tumor cells. PD-L1/L2, co-inhibitory ligands expressed on DCs, play key roles in preventing MiHA-specific CD8-positive T-cell expansion; silencing enhances MiHA-specific CD8-positive T-cell expansion and activity and improves the GVT effect. The MiHA are human leukocyte antigen (HLA)-bound peptides and are exclusively expressed by the recipient's hematopoietic tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5015" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/528" ; obo:OGG_0000000006 "5133" ; obo:VO_0001818 "5015" ; a owl:Class ; rdfs:comment "Gene name: PDCD1" ; rdfs:label "MiHA-loaded PD-L1/L2-silenced Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2531 ] . obo:VO_0007440 obo:IAO_0000115 "A multi-antigen DNA vaccine consisting of plasmids encoding the hepatitis C virus (HCV) nonstructural proteins 3 (NS3), 4A (NS4A), 4B (NS4B) and 5A (NS5A), with potential immunomodulating and cancer preventive activities. Administered via intramuscular injection followed by electroporation, cells transfected with the HCV DNA vaccine INO-8000 express the encoded HCV proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against HCV-infected liver cells expressing the NS3, NS4A, NS4B or NS5A proteins. This results in the eradication of HCV-infected cells. HCV, a small, enveloped, single-stranded RNA virus belonging to the Flaviviridae family, is associated with the development of hepatocellular carcinoma (HCC)" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5002" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/304" ; obo:OGG_0000000006 "3845" ; obo:VO_0001818 "5002" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KRAS" ; rdfs:label "HCV DNA Vaccine INO-8000" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005499, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_684 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007441 obo:IAO_0000115 "A cancer vaccine comprised of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the suicide gene FCU1 with potential antineoplastic activity. FCU1 is a bifunctional yeast cytosine deaminase (CD) / uracil phosphoribosyltransferase (UPRT) fusion gene. Upon intratumoral administration, MVA-FCU1TG4023 enters tumor cells where FCU1 is expressed. Subsequently, the noncytotoxic prodrug 5-fluorocytosine (5-FC) is administered systemically and is deaminated by CD in FCU1- transduced tumor cells into 5-fluorouracil (5-FU), which is then directly metabolized to 5-fluoro-uridine monophosphate (5-FUMP) by UPRT; 5-FUMP may then be further transformed to 5-fluoro-deoxyuridine monophosphate (5-FdUMP), an irreversible inhibitor of thymidylate synthase and, so, DNA synthesis through deprivation of deoxythymidine triphosphate (dTTP). 5-FU and its active metabolites may then selectively kill tumor cells, avoiding toxicity in nonmalignant cells. The MVA viral vector, derived from the replication-competent strain Ankara, is a highly attenuated, replication-defective vaccinia strain incapable of virion assembly" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5312" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/563" ; obo:VO_0001818 "5312" ; a owl:Class ; rdfs:label "MVA-FCU1 TG4023 vaccine" ; rdfs:subClassOf obo:VO_0005499, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_684 ] . obo:VO_0007442 obo:IAO_0000115 "A synthetic HIV vaccine based on a recombinant canary pox virus vector expressing the human immunodeficiency virus (HIV) glycoprotein gp160. HIVgP160 vaccine has been used to generate in vivo primary T lymphocyte response against HIV antigens." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5360" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/308" ; obo:OGG_0000000006 "155971" ; obo:VO_0001818 "5360" ; obo:VO_0005500 "Clinical trial" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Gene name: env" ; rdfs:label "HIVgP160 vaccine" ; rdfs:subClassOf obo:VO_0000295, [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007443 obo:IAO_0000115 "A peptide derived from the oncogenic human papillomavirus (HPV) early gene product E6. The HPV 16 transforming protein E6 is expressed in precancerous and malignant cervical lesions and has a high affinity for the most common human lymphocyte antigen (HLA), HLA-A2. Immunogenic peptides from the HPV 16 E6 may be used to trigger a T-cell-mediated immune response to HPV." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5474" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/429" ; obo:OGG_0000000006 "1489078" ; obo:VO_0001818 "5474" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E6" ; rdfs:label "HPV 16 E6 (18-26) peptide vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007444 obo:IAO_0000115 "A synthetic peptide vaccine consisting of amino acids 86 through 93 (TLGIVCPI) of the viral oncoprotein human papillomavirus (HPV) 16 E7. Vaccination with HPV-16 E7:86-93 peptide, which binds to HLA-A* 0201 molecule, may stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV-16 E7." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5184" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/431" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "5184" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7" ; rdfs:label "HPV 16 E7:86-93 peptide vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007445 obo:IAO_0000115 "A vaccine consisting of human papillomavirus-derived noninfectious virus-like particles (VLPs), containing the L. major capsid protein. Vaccination with HPV 16 L1-VLP results in increases in T cell-proliferative response to HPV 16 L1-VLP, as well as significant increases in cytokine (interferon-gamma, interleukin-5 and -10) responses to L1 VLP. This agent may reduce the incidence of persistent HPV-16 infection, which may be responsible for half of all cases of cervical cancer including high-grade cervical intraepithelial neoplasia." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5520" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/432" ; obo:OGG_0000000006 "25479185" ; obo:VO_0001818 "5520" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: L1" ; rdfs:label "HPV 16 L1-VLP vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007446 obo:IAO_0000115 "A synthetic peptide vaccine consisting of amino acids 13 through 21 of the viral oncoprotein human papillomavirus (HPV) 18 E6. The HPV 18E6 peptide cross-reacts immunologically with both HPV type 16 and HPV type 18, the most common HPV types involved in cervical cancer. Vaccination with HPV-18 E6:13-21 peptide may stimulate the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells positive for HPV 16 and 18." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5159" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/433" ; obo:VO_0001818 "5159" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "HPV 18 E6:13-21 peptide vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007447 obo:IAO_0000115 "Noninfectious, synthetic, virus-like particles (VLP) containing the major viral capsid protein, L1, of the human papillomavirus type 18 with potential immunoprotective activity. Vaccination with HPV 18 L1-VLP may stimulate the host immune system to mount cytotoxic T lymphocyte (CTL) response against cells positive for HPV 18, thereby preventing cervical infection upon exposure to HPV type 18." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5247" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/434" ; obo:VO_0001818 "5247" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "HPV 18 L1-VLP vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007448 obo:IAO_0000115 "A DNA vaccine consisting of plasmids encoding the E6 and E7 genes of human papilloma virus (HPV) subtypes 16 and 18, respectively, with potential immunostimulating and antineoplastic activities. Administered via intramuscular electroporation, HPV DNA plasmids therapeutic vaccine VGX-3100 expresses E6 and E7 proteins, which may elicit a cytotoxic T-lymphocyte (CTL) response against cervical cancer cells expressing E6 and E7 proteins, resulting in tumor cell lysis. HPV type 16 and HPV type 18 are the most common HPV types involved in cervical carcinogenesis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5226" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/435" ; obo:OGG_0000000006 "1489078", "1489079" ; obo:VO_0001818 "5226" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E6|Gene name: E7" ; rdfs:label "HPV DNA plasmids therapeutic vaccine VGX-3100" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007449 obo:IAO_0000115 "A vaccine directed against Human Papillomavirus Type 11 that causes majority of the genital warts and anogenital cancers." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5227" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/437" ; obo:VO_0001818 "5227" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "HPV-11 Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007450 obo:IAO_0000115 "A synthetic agent derived from human papillomavirus (HPV) E7 nuclear protein which is used to produce vaccines against HPV infection and HPV-related neoplasms. HPV E7 oncogenic protein binds the retinoblastoma tumor suppressor protein, pRB, as well as a number of other cellular proteins, and serves as a transcriptional activator. This protein is important in the induction and maintenance of cellular transformation and is co-expressed in the majority of HPV-containing carcinomas. PADRE(R) is a proprietary family of molecules that enhances the immune systems response against an administered immunogen such as the HPV E7 nuclear protein." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5162" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/451" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "5162" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7" ; rdfs:label "human Papillomavirus 16 E7 Peptide/Padre 965.10 Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007451 obo:IAO_0000115 "A recombinant, bivalent, human papillomavirus (HPV) vaccine, containing virus-like particles for HPV types 16 and 18 linked to the adjuvant ASO4, with potential immunoprotective and antineoplastic properties. Upon administration, HPV 16/18 L1 virus-like particle/ASO4 vaccine may generate humoral and cellular immunity against HPV types-16 and -18 antigens, thereby preventing cervical infection upon exposure to HPV types 16 and 18. In addition, this agent may stimulate an antitumoral cellular immune response against cervical cancer associated with HPV infection." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5233" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/452" ; obo:VO_0001818 "5233" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Human Papillomavirus 16/18 L1 virus-like particle/AS04 vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007452 obo:IAO_0000115 "A vaccinia viral based vaccine, encoding epitopes of E6 and E7 proteins from human papillomavirus (HPV) types 16 and 18, with immunostimulatory and antineoplastic activities. HPV types 16 and 18 account for approximately 70% of cervical cancers. Vaccination with this HPV-TA (tumor antigen) vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for E6 and E7 from either type 16 or 18 HPV, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5279" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/453" ; obo:OGG_0000000006 "1489078", "1489079" ; obo:VO_0001818 "5279" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E6|Gene name: E7" ; rdfs:label "Human Papillomavirus Tumor Antigen Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007453 obo:IAO_0000115 "A vaccine consisting of noninfectious, recombinant virus-like particles (VLP) containing the major viral capsid protein L1 of nine strains of human papillomavirus (HPV), with potential immunoprotective activity. Vaccination with HPV V503 may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against cells positive for any of these nine strains of HPV, thereby preventing cervical infection upon exposure to certain HPV subtypes." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5167" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/454" ; obo:VO_0001818 "5167" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: major capsid protein L1" ; rdfs:label "Human Papillomavirus Vaccine V503" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007454 obo:IAO_0000115 "A peptide based vaccine consisting of amino acids 12 through 20 of the E7 gene of the Human Papilloma Virus type 16. HPV-16 E7 12-20 peptide vaccine may elicit a specific CD8 T-cell response to the E7 oncogene protein, thereby inhibiting the abrogation of p53 and pRb function and thus prevent tumorigenesis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5079" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/430" ; obo:OGG_0000000006 "1489079" ; obo:VO_0001818 "5079" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E7" ; rdfs:label "HPV 16 E7:12-20 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007455 obo:IAO_0000115 "A therapeutic DNA vaccine encoding the E6/E7 fusion protein of human papillomavirus (HPV) subtypes 16 and 18, plus the immune-enhancer, Fms-like tyrosine kinase-3 ligand (FLT3L), with potential immunostimulating and antineoplastic activities. DNA vaccine GX-188E is administered using a proprietary delivery system that electroporates the vaccine into cervical cells. Expression of the E6/E7 fusion product may elicit a cytotoxic T-lymphocyte (CTL) response against cervical cancer cells expressing E6 and E7 oncoproteins, resulting in tumor cell lysis. FLT3L is a ligand for the FLT3 tyrosine kinase receptor, which upon activation stimulates the proliferation of hematopoietic progenitor cells. HPV type 16 and 18 are the most common HPV types involved in cervical carcinogenesis" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5083" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/436" ; obo:OGG_0000000006 "1489078", "1489079" ; obo:VO_0001818 "5083" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E6|Gene name: E7" ; rdfs:label "HPV E6/E7 DNA Vaccine GX-188E" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:VO_0007653 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007456 obo:IAO_0000115 "A vaccine consisting of a plasmid DNA encoding the human prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic T cell response against tumor cells that express this antigen, resulting in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5262" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/455" ; obo:OGG_0000000006 "2346" ; obo:VO_0001818 "5262" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Prostate-specific membrane antigen" ; rdfs:label "Human Prostate-Specific Membrane Antigen Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007457 obo:IAO_0000115 "A vaccine consisting of a plasmid DNA encoding the murine prostate-specific membrane antigen (PSMA). Upon administration, expressed PSMA may stimulate a cytotoxic T cell response against tumor cells that express PSMA, resulting in tumor cell lysis" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5105" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/540" ; obo:VO_0001818 "5105" ; a owl:Class ; rdfs:label "Mouse Prostate-Specific Membrane Antigen Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ] . obo:VO_0007458 obo:IAO_0000115 "Early-to late-stage myeloid progenitor cells derived from adult human stem cells with potential hematopoietic activity. Upon infusion, human myeloid progenitor cells CLT-008 proliferate into mature myeloid cells, including granulocytes, macrophages, platelets, and erythrocytes. These myeloid progenitor cells die within forty-five days after a burst of hematopoiesis. This agent cannot create lymphoid cells, including T cells associated with graft-versus-host disease" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5511" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/449" ; obo:VO_0001818 "5511" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Human Myeloid Progenitor Cells CLT-008 vaccine" ; rdfs:subClassOf obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007459 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with corpses of apoptotic leukemic cells, with potential immunostimulatory and antineoplastic activities. Upon vaccination, autologous dendritic cells pulsed with leukemic apoptotic corpse may activate the immune system to mount an anti-tumoral cytotoxic T-lymphocyte (CTL) response against leukemic cells expressing leukemia-associated antigens, which may result in leukemic cell lysis and inhibition of tumor cell growth. Apoptotic tumor cell corpses contain an array of tumor associated antigens" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5004" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/476" ; obo:VO_0001818 "5004" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells Vaccine" ; rdfs:subClassOf obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007460 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5200" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/555" ; obo:OGG_0000000006 "3077513", "3077579" ; obo:VO_0001818 "5200" ; a owl:Class ; rdfs:comment "Gene name: UL83|Gene name: UL123" ; rdfs:label "Multi-peptide CMV-Modified Vaccinia Ankara Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005427, obo:VO_0005487, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1240 ] . obo:VO_0007461 obo:IAO_0000115 "This is an autologous lung cancer vaccine consisting of patient-specific lung cancer cells genetically modified to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), an immunostimulatory cytokine (NCIT_C1979). GM-CSF modulates the proliferation and differentiation of a variety of hematopoietic progenitor cells with some specificity towards stimulation of leukocyte production and may reverse treatment-induced neutropenias." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5453" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/302" ; obo:OGG_0000000006 "1437" ; obo:VO_0001818 "5453" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM-CSF" ; rdfs:label "GVAX Lung Cancer Vaccine" ; rdfs:subClassOf obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007463 obo:IAO_0000115 "A peptide vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. gp100:280-288(288V) peptide has a valine substitution at amino acid position 288 to improve immunogenicity. Vaccination with gp100:280-288(288V) peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5112" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/419" ; obo:OGG_0000000006 "3791" ; obo:VO_0001818 "5112" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KDR" ; rdfs:label "HLA-A*2402-Restricted VEGFR1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005486, obo:VO_0005489, obo:VO_0005490, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10534 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1993 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9256 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007464 obo:IAO_0000115 "A cancer vaccine containing two HLA-A*0201-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from: vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A*0201-restricted VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing VEGFR 1 and 2 peptides, resulting in tumor cell lysis and decreased tumor growth. HLA-A*0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5294" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/420" ; obo:OGG_0000000006 "3791" ; obo:VO_0001818 "5294" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KDR" ; rdfs:label "HLA-A2402-Restricted VEGFR1/2 Multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005486, obo:VO_0005489, obo:VO_0005490, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10534 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1993 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9256 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007465 obo:IAO_0000115 "A cancer vaccine consisting of allogeneic neuroblastoma tumor cells have been genetically modified to secrete the human cytokine interleukin-2 (IL-2) and the human chemokine lymphotactin (Lptn) with potential immunostimulating and antineoplastic activities. Upon administration, IL-2 and Lptn are secreted by the IL-2/Lptn gene-modified allogeneic neuroblastoma tumor cell vaccine, potentially enhancing the cytotoxic T lymphocyte (CTL) response elicited by vaccine neuroblastoma tumor-associated antigens (TAAs) against host neuroblastoma tumor cells. Produced by activated progenitor T cells, Lptn belongs to the C chemokine subfamily and is a potent chemotactic factor for lymphocytes; IL-2 stimulates natural killer (NK) cells and may enhance a vaccine-elicited CTL immune response against tumor cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5173" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/462" ; obo:OGG_0000000006 "6375" ; obo:VO_0001818 "5173" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: XCL1" ; rdfs:label "IL-2/Lptn Gene-Modified Allogeneic Neuroblastoma Tumor Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007466 obo:IAO_0000115 "An immunotherapeutic containing a proprietary adjuvant system combined with a melanoma-associated antigen peptide MAGE-A3 epitope with potential immunomodulating and antineoplastic activities. Intramuscular administration with GSK1572932A may stimulate the immune system to exert both humoral and cellular immune responses against MAGE-A3-expressing tumor cells. MAGE-A3, a tumor associated antigen (TAA), is overexpressed in a variety of tumor cell types, including non-small cell lung cancer (NSCLC), melanoma, head and neck cancer, and bladder cancer." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5343" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/463" ; obo:OGG_0000000006 "4102" ; obo:VO_0001818 "5343" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3" ; rdfs:label "Immunotherapeutic GSK1572932A" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007467 obo:IAO_0000115 "GVAX cancer vaccines are autologous cell vaccines comprised of tumor cells which have been irradiated and genetically modified to secrete granulocyte-macrophage colony stimulating factor (GM-CSF), a hormone which plays a key role in stimulating the body's immune response to vaccines." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5211" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/301" ; obo:OGG_0000000006 "1493", "354" ; obo:VO_0001818 "5211" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTLA4|Gene name: KLK3" ; rdfs:label "GVAX Cancer Vaccine" ; rdfs:subClassOf obo:VO_0005425, obo:VO_0005430, obo:VO_0005486, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1324 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007468 obo:IAO_0000115 "A replication-defective adenoviral serotype 5 vector encoding a recombinant form of the human cytokine interferon-gamma (IFN-g), with potential antineoplastic and immunoregulatory activities. Upon intratumoral administration, the sustained expression of IFN-g by IFN-g-expressing adenovirus vaccine ASN-002 promotes a T-helper type 1 (Th1) immune response and inhibits the Th2-mediated cytokine production observed in many cutaneous lymphomas. IFN-g also mediates interleukin-12 (IL-12) production by antigen-presenting cells (APCs); activates macrophages, cytotoxic T-cells, and natural killer (NK) cells; upregulates major histocompatibility complex (MHC) molecules; and stimulates antibody-dependent cellular cytotoxicity (ADCC). Altogether, these IFN-g-mediated effects may result in both an inhibition of tumor cell proliferation and tumor cell death. Compared to IFN-g injections, the prolonged local production of IFN-g at the tumor site allows for higher efficacy and a reduction of systemic toxicity" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5540" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/470" ; obo:OGG_0000000006 "2546420" ; obo:VO_0001818 "5540" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: WHcAg" ; rdfs:label "Interferon-gamma-expressing Adenovirus Vaccine ASN-002" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007469 obo:IAO_0000115 "A vaccine based on anti-idiotype (Id) monoclonal antibodies combined with interleukin-2 (IL-2). Anti-Id vaccines have been shown to be effective in treatment of B-cell lymphoma in animal models and in clinical trials, resulting in tumor regression; the addition of interleukin-2 (IL-2) may augment the therapeutic effect of anti-Id vaccines." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5352" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/471" ; obo:OGG_0000000006 "5176180" ; obo:VO_0001818 "5352" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp72" ; rdfs:label "Interleukin-2 Anti-Idiotype Vaccine" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007470 obo:IAO_0000115 "A chimeric lymphoma vaccine generated by combining the recipient's Ig idiotype (Id) protein with keyhole limpet hemocyanin (KLH), an immune stimulant, with potential antineoplastic activity. Vaccination with KLH-Lymphoma Ig Vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against lymphoma cells, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5519" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/474" ; obo:VO_0001818 "5519" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "KLH-Lymphoma Ig Vaccine" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007471 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0004398 ; a owl:Class ; rdfs:comment "Gene name: Fragment C from tetanus toxin" ; rdfs:label "obsolete Lymphoma DNA vaccine V_V_V_-FrC" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0007472 obo:IAO_0000115 "A preparation of autologous peripheral blood mononuclear cells (PBMCs) radiolabeled with indium In 111 with radioisotopic activity. Autologous PBMCs are isolated, expanded ex vivo, radiolabeled with indium In 111, and then infused back into the patient. Gamma scintigraphy may then be used to image gamma ray-emitting indium In 111 PBMCs localized in lymphoma tissue." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5212" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/467" ; obo:OGG_0000000006 "1048" ; obo:VO_0001818 "5212" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5" ; rdfs:label "Indium In 111-Labeled Autologous Peripheral Blood Mononuclear Cells Vaccine" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10154 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007473 obo:IAO_0000115 "A preparation of autologous peripheral polymorphonuclear (PMNLs) radiolabeled with indium In 111 with radioisotopic activity. Autologous PMNLs are isolated, expanded ex vivo, radiolabeled with indium In 111, and then infused back into the patient. Gamma scintigraphy may then be used to image gamma ray-emitting indium In 111 PMNLs localized in lymphoma tissue." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5273" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/468" ; obo:VO_0001818 "5273" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Indium In 111-Labeled Autologous Polymorphonuclear Leukocytes Vaccine" ; rdfs:subClassOf obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10154 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007474 obo:IAO_0000115 "Human peripheral blood lymphocytes (PBL) isolated from a patient, exposed to the tumor-associated protein ESO-1 in vitro, and then transferred back to the same patient to target tumor cells expressing ESO-1. ESO-1 is a human self-antigen expressed by melanomas. The ESO-1 gene encodes several MHC class I- and MHC class II-restricted epitopes that may activate cytotoxic T-cell-mediated tumor destruction" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5178", "https://pubmed.ncbi.nlm.nih.gov/?term=ESO-1+Reactive+Autologous+Peripheral+Blood+Lymphocyte" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/67" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5178" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "ESO-1 Reactive Autologous Peripheral Blood Lymphocyte vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007475 obo:IAO_0000115 "A recombinant fowlpox virus-based vaccine vector designed to express various tumor-associated peptide antigens. Strong CD8 cytotoxic T cell responses may be induced after prolonged immunization with fowlpox virus vaccines and have been associated with tumor regression. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5042" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/130" ; obo:OGG_0000000006 " 4582", "1048" ; obo:VO_0001818 "5042" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM5|Gene name: MUC1" ; rdfs:label "Fowlpox Virus Vector Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007476 obo:IAO_0000115 "A cancer vaccine containing of a synthetic form of the renal cell carcinoma (RCC)-associated antigen G250 with potential antineoplastic activity. Vaccination with G250 peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the G250 antigen, resulting in decreased tumor growth. Found in the majority of renal cell carcinomas, G250 is a cell surface tumor-associated antigen (TAA) that contains an HLA-A2.1-restricted epitope that is recognized by CTLs." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5249" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/135" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5249" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MLANA" ; rdfs:label "Gag:267-274 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007477 obo:IAO_0000115 "An autologous dendritic cell (DC) cancer vaccine with GITRL RNA-transfected that has potential immunostimulatory activity. " ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5410" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/136" ; obo:OGG_0000000006 "1493" ; obo:VO_0001818 "5410" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CTLA4" ; rdfs:label "GITRL RNA-transfected Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007478 obo:IAO_0000115 "Used C57BL/6 mice and irradiated B16 tumor cells expressing granulocyte and macrophage colony-stimulating factor (GM-CSF), interleukin-12 (IL-12) or both. Tumor was transplanted by the injection of wild-type B16 cells. Tumor growth and survival were measured to evaluate the efficacy of vaccination. Specific humoral response and immunoglobulin G (IgG) switch were evaluated measuring total IgG and IgG1 and IgG2a subtypes against tumor membrane proteins of B16 cells" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4061" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/176" ; obo:VO_0001818 "4061" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "GM-CSF, IL-12 and GM-CSF+IL-12 genetically modified tumor cell vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007479 obo:IAO_0000115 "A recombinant, oncolytic serotype 5/3 capsid-modified adenovirus encoding the immunostimulatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) with potential antineoplastic activity. Upon administration, the oncolytic adenovirus selectively infects and replicates in tumor cells, which may result in tumor cell lysis. Synergistically, GM-CSF (sargramostim) expressed by the oncolytic adenovirus enhances antigen presentation, promotes natural killer (NK) cell-mediated killing and causes a cytotoxic T cell (CTL) response against tumor cells harboring the oncolytic adenovirus, resulting in an immune-mediated tumor cell death. CGTG-102 is designed to replicate only in cells with defects in the p16/Rb/E2F pathway, attributed to a mutation common in many solid tumors. Replacement of the Ad5 capsid protein knob with a knob domain from serotype 3 causes higher transduction in cancer cells as compared to normal cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5111" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/177" ; obo:VO_0001818 "5111" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "GM-CSF-encoding Oncolytic Adenovirus CGTG-102 vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007481 obo:IAO_0000115 "A vaccine that injected peptides of gp100, MART-1, MAGE-3" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3993" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/196" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "3993" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100 + Mart-1 + Mart-3 vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007482 obo:IAO_0000115 "A vaccine consisting of a replication-defective recombinant adenovirus that encodes the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. Vaccination with gp100 adenovirus vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5133" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/197" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5133" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100 Adenovirus Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007483 obo:IAO_0000115 "A vaccine consisting of microscopic gold particles coated with plasmid DNA encoding the glycoprotein 100 (gp100) melanoma antigen and granulocyte-macrophage colony-stimulating factor (GM-CSF). Vaccination with gp100 and GM-CSF DNA/gold vaccine may stimulate the host immune system to direct cytotoxic T lymphocytes (CTL) against gp100 positive cells, resulting in decreased tumor growth. GM-CSF is thought to increase the induction and activation of antigen-presenting cells (APC), allowing for a reduction in the dose of gp100 administered." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5084" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/198" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5084" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100 and GM-CSF DNA/Gold Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007484 obo:IAO_0000115 "A recombinant peptide derived from the human melanoma antigen glycoprotein 100 (gp100) with potential use in cancer immunotherapy. gp100 protein(184V) has a valine substitution at position 184. Vaccination with this peptide may evoke a cytotoxic T lymphocyte (CTL) response against tumor cells expression the gp100 antigen." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5482" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/199" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5482" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100 Protein (184V) vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007485 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant vaccinia virus encoding the gp100 melanoma-melanocyte antigen. gp100 human antigen is a wild-type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5153" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/200" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5153" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100 Vaccinia Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007486 obo:IAO_0000115 "A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the melanoma antigen glycoprotein 100 (gp 100) with potential antineoplastic activity. The expression of gp100 may generate a cellular immune response to melanoma cells; this effect is enhanced by the co-administration of interleukin 2" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5135" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/201" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5135" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100-Fowlpox Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007487 obo:IAO_0000115 "Peripheral blood lymphocytes (PBL) harvested from host blood and stimulated in vitro with tumor-specific gp 100 antigen. 'Pulsing' PBL with gp100, a tumor associated antigen (TAA) commonly expressed by melanoma cells, may increase melanoma-reactive cytotoxic lymphocytes (CTL) in the PBL cell population. Autologous gp100-pulsed PBL have been administered to melanoma patients in order to augment cytotoxic immune responses to melanoma." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5007" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/202" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5007" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100-Pulsed Peripheral Blood Mononuclear Cell vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007488 obo:IAO_0000115 "Human peripheral blood lymphocytes (PBL) isolated from a patient, exposed to the tumor-associated antigen gp100 in vitro, and then transferred back to the same patient to target tumor sites expressing gp100. gp100 human antigen is a wild-type self-antigen expressed by melanocytes, pigmented retinal cells and most melanomas." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4990" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/203" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "4990" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100-Reactive Autologous Peripheral Blood Lymphocyte vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007489 obo:IAO_0000115 """To understand why cancer vaccine-induced T cells often do not eradicate tumors, we studied immune responses in mice vaccinated with gp100 melanoma peptide in incomplete Freund's adjuvant (peptide/IFA), which is commonly used in clinical cancer vaccine trials (Hailemichael et al., 2013). Immunization Route: Intramuscular injection (i.m.)""" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4078" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/204" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "4078" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100/IFA vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007490 obo:IAO_0000115 "A synthetic peptide vaccine consisting of amino acids 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen with an endoplasmic reticulum signal sequence (ES) to increase binding activity. Vaccination with gp100:ES209-217(210M) may stimulate the host immune system to mount a cytotoxic T lymphocyte response against tumor cells positive for gp100, resulting in decreased tumor growth" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5095" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/205" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5095" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100: ES209-217(210M) Peptide vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007491 obo:IAO_0000115 "A peptide consisting of amino acid residues 154 through 162 of the melanoma-melanocyte antigen gp100. Vaccination with gp100:154-162 peptide may enhance tumor-specific T-cell immunity. gp100 antigen is a self-antigen expressed by melanocytes, pigmented retinal cells, and most melanoma lesions and is recognized via class I and II HLA-restricted mechanisms." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5145" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/206" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5145" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100:154-162 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007492 obo:IAO_0000115 "A synthetic peptide vaccine consisting of amino acids 209 through 217 of the glycoprotein 100 (gp100) melanoma antigen with an endoplasmic reticulum signal sequence (ES) to increase binding activity. Vaccination with gp100:ES209-217(210M) may stimulate the host immune system to mount a cytotoxic T lymphocyte response against tumor cells positive for gp100, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5050" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/207" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5050" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100:209-217 Peptide vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007493 obo:IAO_0000115 "A vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. Vaccination with gp100:280-288 peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5526" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/208" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "5526" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "gp100:280-288 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007494 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3989" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/307" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "3989" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "Hexapeptide melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007495 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A1-binding melanoma-associated antigen peptides MAGE-1 and MAGE-3 with potential immunomodulating and antineoplastic activity. Upon vaccination, HLA-A1-binding MAGE-1/MAGE-3 multipeptide-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount an anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against MAGE1- and MAGE-3-expressing cancer cells, resulting in tumor cell lysis. HLA-A1 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A1 may improve antigenic peptide immunogenicity." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5185" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/423" ; obo:OGG_0000000006 "4100", "4102" ; obo:VO_0001818 "5185" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3|Gene name: MAGEA1" ; rdfs:label "HLA-A1-Binding MAGE-1/MAGE-3 Multipeptide-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007496 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with human leukocyte antigen (HLA)-A2-restricted melanoma-associated antigen peptides tyrosinase (TYR), MART-1(melanoma antigen recognized by T-cells) and melanoma antigen glycoprotein 100 (gp100), with potential immunomodulating and antineoplastic activity. Upon vaccination, HLA-A2-binding TYR/MART-1/gp100 multipeptide-pulsed autologous dendritic cell vaccine may stimulate the host immune system to mount an anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against Tyr-, MART-1 and gp100-expressing cancer cells, resulting in tumor cell lysis. HLA-A2 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A2 may improve antigenic peptide immunogenicity." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5034" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/425" ; obo:OGG_0000000006 "2315", "6490" ; obo:VO_0001818 "5034" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: gp100 |Gene name: MLANA" ; rdfs:label "HLA-A2-Binding TYR/MART-1/gp100 Multipeptide-Pulsed Autologous Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007497 obo:IAO_0000115 "A cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding human telomerase reverse transcriptase (hTERT) and survivin in addition to patient-specific melanoma-derived mRNA with potential immunostimulatory and antineoplastic activities. Upon administration, hTERT/survivin/melanoma tumor cell-derived mRNA-transfected dendritic cell vaccine may elicit a highly specific cytotoxic T-cell (CTL) response against melanoma cells expressing hTERT, survivin, and patient-specific melanoma-associated antigens. hTERT, the catalytic subunit of human telomerase, and survivin, a member of the inhibitor of apoptosis (IAP) family of proteins, may be upregulated in certain tumor cell types, playing key roles in tumor cell growth and survival. " ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5270" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/448" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5270" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "hTERT/Survivin/Melanoma Tumor Cell-Derived mRNA-Transfected Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007498 obo:IAO_0000115 "A peptide vaccine consisting of a combination of seven synthetic long peptides (SLPs), which are each about 30 amino acids in size, and derived from cancer-testis antigens (CTA) and melanocytic differentiation proteins (MDP), with potential immunostimulating and antitumor activities. Upon administration, long peptide vaccine 7 may stimulate the host immune system to mount a cytotoxic T-cell lymphocyte (CTL) response against tumor cells expressing these peptides. CTA and MDP are overexpressed in a variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5143" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/484" ; obo:OGG_0000000006 "3845", "7157" ; obo:VO_0001818 "5143" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TP53|Gene name: KRAS" ; rdfs:label "Long Peptide Vaccine 7" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007499 obo:IAO_0000115 "A synthetic peptide cancer vaccine consisting of human leukocyte antigen HLA-A1-restricted peptide derived from human melanoma antigen 3 (MAGE-3) with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-3.A1 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-3, resulting in tumor cell lysis. MAGE-3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5021" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/489" ; obo:OGG_0000000006 "4102" ; obo:VO_0001818 "5021" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3" ; rdfs:label "MAGE-3.A1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007501 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4003" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/497" ; obo:OGG_0000000006 "6490" ; obo:VO_0001818 "4003" ; a owl:Class ; rdfs:comment "Gene name: gp100" ; rdfs:label "MART-1 Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007502 obo:IAO_0000115 "A vaccine consisting of recombinant adenovirus vector encoding MART-1 (melanoma antigen recognized by T-cells 1), an immunogenic protein of unknown function that is expressed by certain types of melanoma. Vaccination with MART-1 adenovirus vaccine may stimulate the host immune system to direct cytotoxic T lymphocytes (CTL) against MART-1 positive melanoma cells, resulting in an antitumor effect." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5398" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/498" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5398" ; a owl:Class ; rdfs:comment "Gene name: MLANA-Dupli" ; rdfs:label "MART-1 Adenovirus Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007503 obo:IAO_0000115 "A synthetic cancer vaccine derived from a melanoma-associated antigen, MART-1. Antigenic peptides derived from MART-1 are recognized by CD8+ T lymphocytes and have been used to immunize patients with advanced melanomas; prolonged immunization may result in a reduction in tumor size. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5254" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/502" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5254" ; a owl:Class ; rdfs:comment "Gene name: MLANA-Dupli" ; rdfs:label "MART-1 Fowlpox Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007504 obo:IAO_0000115 "A cancer vaccine consisting of an attenuated recombinant vaccinia virus expressing the melanoma-associated antigen MART-1. Vaccination with this agent may stimulate cytotoxic host immune responses to melanoma cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5204" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/503" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5204" ; a owl:Class ; rdfs:comment "Gene name: MLANA-Dupli" ; rdfs:label "MART-1 Vaccinia Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007505 obo:IAO_0000115 "Irradiated allogeneic, HLA-A*0201 positive, plasmacytoid dendritic cells (pDCs) loaded with 4 melanoma peptides derived from the tumor associated antigens (TAAs) MelA/MART-1, gp100/pmel17, tyrosinase, and MAGE-A3, with potential immunostimulating and antineoplastic activities. Upon subcutaneous administration, the irradiated allogeneic pDCs may trigger functional multi-specific T cells from peripheral blood mononuclear cells and tumor-infiltrating lymphocytes, and activate the immune system to mount a cytotoxic T-lymphocyte response against HLA-A*0201 positive melanoma cancer cells expressing the TAAs MelA/MART-1, gp100/pmel17, tyrosinase, and MAGE-A3. These TAAs are upregulated in a variety of tumor cells. The pDCs are derived from a distinct subset of dendritic cells (DCs) with a plasma cell-like morphology and express a characteristic set of surface markers and may increase the anti-tumor immune responses." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5028" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/504" ; obo:OGG_0000000006 "4100", "6490" ; obo:VO_0001818 "5028" ; a owl:Class ; rdfs:comment "Gene name: gp100|Gene name: MAGEA3" ; rdfs:label "MART-1/gp100/Tyrosinase/MAGE-A3 Peptides-loaded Irradiated Allogeneic Plasmacytoid Dendritic Cells Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007506 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5141" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/505" ; obo:OGG_0000000006 "2315", "6490" ; obo:VO_0001818 "5141" ; a owl:Class ; rdfs:comment "Gene name: MLANA|Gene name: gp100" ; rdfs:label "MART-1:26-35(27L) Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007507 obo:IAO_0000115 "A natural or synthetic peptide cancer vaccine consisting of amino acid residues 27 through 35 of the melanoma-associated antigen MART-1 with potential antineoplastic activity. Vaccination with MART-1:27-35 peptide may induce cytotoxic host immune responses against melanoma cells that express this peptide" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5450" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/506" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5450" ; a owl:Class ; rdfs:comment "Gene name: MLANA" ; rdfs:label "MART-1:27-35 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007508 obo:IAO_0000115 "A vaccine consisting of the melanocyte differentiation antigen Melan A (also called MART-1) encapsulated in noninfectious virus-like particles (VLP) with potential immunostimulating and antineoplastic activities. Upon administration, Melan-A VLP vaccine may activate the immune system to exert a specific cytotoxic T lymphocyte (CTL) response against cancer cells expressing the Melan A antigen, resulting in tumor cell lysis. Melan A is an antigen that is upregulated in most melanomas. VLP stimulates the immune system and promotes the CTL response." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5142" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/507" ; obo:OGG_0000000006 "2315" ; obo:VO_0001818 "5142" ; a owl:Class ; rdfs:comment "Gene name: MLANA" ; rdfs:label "Melan-A VLP Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007509 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5318" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/508" ; obo:OGG_0000000006 "2315", "4102" ; obo:VO_0001818 "5318" ; a owl:Class ; rdfs:comment "Gene name: MLANA|Gene name: MAGEA3" ; rdfs:label "Melan-A/MAGE-3.DP4 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007518 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/517" ; obo:OGG_0000000006 "7299" ; a owl:Class ; rdfs:comment "Gene name: Tyrosinase" ; rdfs:label "Melanoma DNA vaccine TA2M(TM) encoding tyrosinase peptides" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007523 obo:IAO_0000115 "A synthetic allogeneic cancer vaccine. Melanoma theraccine typically consists of lysed melanoma cells obtained from several melanoma cell lines combined with an adjuvant (such as DETOX or RIBI). This agent may be combined with immunomodulatory cytokines such as interferon alpha. Melanoma theraccine may induce a rise in the level of cytotoxic T-lymphocyte precursors." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4989" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/522" ; obo:OGG_0000000006 "282617" ; obo:VO_0001818 "4989" ; a owl:Class ; rdfs:comment "Gene name: IFNL3" ; rdfs:label "Melanoma Theraccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007524 obo:IAO_0000115 "A therapeutic melanoma vaccine consisting of autologous dendritic cells (DCs) pulsed with antigens from lethally irradiated autologous tumor cells derived from a patient-specific, continuously proliferating and melanoma-initiating cell line and suspended in a solution containing the cytokine granulocyte-macrophage colony stimulating factor (GM-CSF), with potential immunostimulatory and antineoplastic activities. Upon subcutaneous administration, melapuldencel-T may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL) immune response against the patient's repertoire of melanoma-associated antigens, particularly tumor stem cell antigens, found in the irradiated autologous cancer cells. As an immunostimulant, GM-CSF enhances the activation of dendritic cells (DCs) and promotes antigen presentation to both B- and T-lymphocytes." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5014" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/523" ; obo:VO_0001818 "5014" ; a owl:Class ; rdfs:label "Melapuldencel-T Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007525 obo:IAO_0000115 "A multipeptide cancer vaccine comprised of 12 melanoma peptides restricted by Class I MHC (12MP), plus a tetanus helper peptide" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5261" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/524" ; obo:OGG_0000000006 "22178", "6490" ; obo:VO_0001818 "5261" ; a owl:Class ; rdfs:comment "Gene name: gp100|Gene name: TRP-1" ; rdfs:label "MELITAC 12.1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007527 obo:IAO_0000115 "A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2 with potential immunostimulating and antineoplastic activities. Upon administration, monoclonal antibody 4B5 anti-idiotype vaccine may elicit both cellular and humoral immune responses against GD2- expressing tumor cells. GD2 is a glycosphingolipid (ceramide and oligosaccharide) that may be highly expressed by melanomas and other neuroectodermal tumors, while only minimally expressed by normal tissues." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5039" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/535" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5039" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Monoclonal Antibody 4B5 Anti-Idiotype Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007528 obo:IAO_0000115 "A vaccine consisting of a plasmid DNA encoding the murine melanoma-associated antigen gp100. Upon administration, expressed gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against tumor cells that express the gp100 antigen, resulting in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5386" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/539" ; obo:OGG_0000000006 "20431" ; obo:VO_0001818 "5386" ; a owl:Class ; rdfs:comment "Gene name: Pmel17" ; rdfs:label "Mouse gp100 Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007529 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/543" ; obo:OGG_0000000006 "768" ; a owl:Class ; rdfs:comment "Gene name: CA9" ; rdfs:label "mRNA-Electroporated Dendritic Cells Vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007531 obo:IAO_0000115 "A plasmid DNA vaccine encoding the mouse tumor associated antigen tyrosinase-related protein-2 (TYRP2) with potential immunostimulating and antineoplastic activities. Upon administration, murine TYRP2 plasmid DNA vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing TYRP2; this vaccine may also induce an immune response against tyrosinase-related protein-1 (TYRP1). TYRP2 and TYRP1, melanosomal membrane glycoproteins upregulated in melanoma cells, are involved in melanin synthesis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5310" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/558" ; obo:OGG_0000000006 "1638" ; obo:VO_0001818 "5310" ; a owl:Class ; rdfs:comment "Gene name: DCT" ; rdfs:label "Murine TYRP2 Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007532 obo:IAO_0000115 "A cancer vaccine containing dendritic cells (DCs) that are transfected with messenger RNA (mRNA) encoding human telomerase reverse transcriptase (hTERT) and LAMP. " ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5276" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/446" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5276" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "hTERT-LAMP mRNA-loaded Autologous Dendritic Cell Vaccine GRNVAC1" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007533 obo:IAO_0000115 "A recombinant 19-residue peptide vaccine consisting of amino acids 161 through 180 of the cancer/testis (CT) antigen. ESO-1 (161-180) peptide vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for ESO-1, resulting in decreased tumor growth. ESO-1 is expressed in a variety of cancers, including melanoma, breast, bladder, prostate, and hepatocellular cancers. (NCI04) (NCIT_C28775)." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5264" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/66" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5264" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "ESO-1 (161-180) Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, obo:VO_0005425, obo:VO_0005484, obo:VO_0005485, obo:VO_0005499, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_684 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007534 obo:IAO_0000115 "A 9-residued peptide vaccine consisting of amino acids 157 through 165 of the cancer/testis (CT) antigen ESO-1. Modified at position 165 (cysteine to valine) to improve immunogenicity, ESO-1:157-165(165v) peptide administered as a vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for ESO-1, resulting in decreased tumor growth. ESO-1 is expressed in a variety of cancers, including melanoma, breast, bladder, prostate, and hepatocellular cancers." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5473", "https://pubmed.ncbi.nlm.nih.gov/?term=ESO-1%3A157-165%28165V%29+Peptide" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/68" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "5473" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: NY-ESO-1" ; rdfs:label "ESO-1:157-165(165V) Peptide vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, obo:VO_0005425, obo:VO_0005484, obo:VO_0005485, obo:VO_0005499, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_684 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007535 obo:IAO_0000115 "A recombinant virus-based vaccine that contains various peptide antigens. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues. Strong CD8 T cell responses may be induced after prolonged immunization and have been associated with tumor regression." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "PubMed:15757474", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5031" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/129" ; obo:OGG_0000000006 "354", "634" ; obo:VO_0001818 "5031" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CEACAM1|Gene name: KLK3" ; rdfs:label "Fowlpox Virus Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007536 obo:IAO_0000115 "A peptide vaccine against the immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO), with potential immunomodulating and antineoplastic activities. Vaccination with indoleamine 2,3-dioxygenase peptide vaccine may activate the immune system to induce an immune response against IDO-expressing cells. This may increase and restore the proliferation and activation of various immune cells, including dendritic cells (DCs), natural killer (NK) cells, and T-lymphocytes, and may eradicate IDO-expressing tumor cells. IDO, a cytosolic enzyme responsible for tryptophan catabolism and conversion of tryptophan into kynurenine, is overexpressed by a variety of tumor cell types and antigen presenting cells (APCs) and plays an important role in immunosuppression; Tryptophan depletion inhibits T-lymphocyte proliferation and activation, and suppresses the immune system" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5144" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/469" ; obo:OGG_0000000006 "3620" ; obo:VO_0001818 "5144" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: IDO1" ; rdfs:label "Indoleamine 2,3-dioxygenase Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007537 obo:IAO_0000115 "A conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic activity. Folate-FITC binds to folate receptors, which are overexpressed on the surfaces of many cancer cells including kidney and ovarian cancer cells. Once bound to the cancer cell through the folate moiety of the conjugate, circulating anti-fluorescein antibodies may recognize and bind to the FITC moiety, resulting in antibody-dependent cellular cytotoxicity. " ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "PubMed:22855837", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5317" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/128" ; obo:OGG_0000000006 "2348" ; obo:VO_0001818 "5317" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: FOLR1" ; rdfs:label "Folate-FITC vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007538 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant vaccinia virus encoding the tumor-associated gene MAGE-1 that is contaminated with bovine viral diarrhea virus (BVDV). The MAGE-1 gene is a member of the melanoma antigen-encoding gene family which is expressed in various malignant tumors such as hepatocellular carcinoma and germ cell tumors in addition to melanoma. Vaccination with vaccinia virus expressing human MAGE-1 may generate antitumoral T-cell responses. BVDV is an RNA pestivirus that may contaminate vaccines due to its presence in the fetal calf serum used as a growth supplement in the tissue culture of mammalian cells used in vaccine production." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5157" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/488" ; obo:OGG_0000000006 "4100" ; obo:VO_0001818 "5157" ; a owl:Class ; rdfs:comment "Gene name: MAGEA1" ; rdfs:label "MAGE-1 Vaccinia Contaminated with BVDV" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007539 obo:IAO_0000115 "A peptide cancer vaccine comprised of a peptide derived from the human melanoma antigen A3 (MAGE-A3), with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-A3 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-A3, resulting in tumor cell lysis. MAGE-A3, a tumor-associated antigen (TAA), is overexpressed by a variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5395" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/491" ; obo:OGG_0000000006 "4102" ; obo:VO_0001818 "5395" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3" ; rdfs:label "MAGE-A3 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007540 obo:IAO_0000115 "An oncolytic adenoviral vaccine composed of a replication-defective, E1- and E3-deleted adenovirus serotype 5 (Ad5) with a transgene encoding the human melanoma antigen A3 (MAGE-A3), with potential antineoplastic activity. Upon administration, MAGE-A3-expressing adenovirus type 5 vaccine selectively replicates in cancer cells and expresses MAGE-A3. This induces an immune response against tumor cells expressing the MAGE-A3 antigen, which leads to tumor cell death. The tumor-associated antigen MAGE-A3 is overexpressed by a variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5336" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/492" ; obo:OGG_0000000006 "4102" ; obo:VO_0001818 "5336" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3" ; rdfs:label "MAGE-A3-expressing Adenovirus Type 5 Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007541 obo:IAO_0000115 "A peptide vaccine consisting of multiple epitopes derived from the human telomerase reverse transcriptase (hTERT), the catalytic subunit of human telomerase, with potential immunostimulating and antineoplastic activities. hTERT I540/R572Y/D988Y multipeptide vaccine contains strongly antigenic peptide epitopes I540 (9-mer), R572Y (9-mer) and D988Y (10-mer). Vaccination with this agent may elicit a cytotoxic T cell (CTL) response against telomerase-expressing tumor cells. Directly linked to tumorigenesis, telomerase is expressed in the majority of human cancer cells but is infrequently expressed in normal cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5191" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/439" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "5191" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "hTERT I540/R572Y/D988Y Multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005427, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_6536 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007542 obo:IAO_0000115 "A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with tumor-derived clonal immunoglobulin (Ig) with potential immunostimulatory and antineoplastic activities. Upon administration, idiotype-pulsed autologous dendritic cell vaccine APC8020, containing idiotype (Id) protein structures that can be recognized by antibodies and by CD41 T lymphocytes and CD81 T lymphocytes, may stimulate antitumoral cytotoxic T lymphocyte (CTL) and antibody responses against Id-expressing tumor cells. The Id represents the unique antigenic determinants in the variable regions of the clonal Ig." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5344" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/460" ; obo:VO_0001818 "5344" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Idiotype-Pulsed Autologous Dendritic Cell Vaccine APC8020" ; rdfs:subClassOf obo:VO_0005427, obo:VO_0005492, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_6536 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9538 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007544 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain of the Epstein Barr Virus (EBV) antigen EBNA1 and fused to the full-length of the EBV-associated antigen latent membrane protein 2 (LMP2), with potential immunostimulatory and antineoplastic activities. Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2. Multi-antigen vaccine therapy may be more efficacious than single-antigen therapy vaccine therapy. EBNA1, a sequence-specific DNA binding protein, plays an important role in EBV episomal genome maintenance and gene transactivation." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5460" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/565" ; obo:OGG_0000000006 "354", "55" ; obo:VO_0001818 "5460" ; a owl:Class ; rdfs:comment "Gene name: KLK3|Gene name: ACP3" ; rdfs:label "MVA-PSA/PAP Prostate Cancer Vaccine" ; rdfs:subClassOf obo:VO_0005498, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9261 ] . obo:VO_0007545 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding the gene for the CD4 epitope-rich C-terminal domain of the Epstein Barr Virus (EBV) antigen EBNA1 and fused to the full-length of the EBV-associated antigen latent membrane protein 2 (LMP2), with potential immunostimulatory and antineoplastic activities. Upon administration, MVA EBNA1/LMP2 vaccine may elicit a cytotoxic T-cell immune response against cancer cells expressing EBNA1 and LMP2. Multi-antigen vaccine therapy may be more efficacious than single-antigen therapy vaccine therapy. EBNA1, a sequence-specific DNA binding protein, plays an important role in EBV episomal genome maintenance and gene transactivation. (NCIT_C91076)." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5314" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/560" ; obo:OGG_0000000006 "3783709", "5698" ; obo:VO_0001818 "5314" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: EBNA-1|Gene name: PSMB9" ; rdfs:label "MVA-EBNA1/LMP2 Vaccine" ; rdfs:subClassOf obo:VO_0005498, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9261 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007546 obo:IAO_0000115 "A peptide vaccine containing amino acids residues from 340 through 349 of the latent membrane protein-2 (LMP-2) of the Epstein-Barr virus (EBV) with potential immunostimulating and antineoplastic activities. LMP-2, an EBV transmembrane protein, is expressed in various malignancies including nasopharyngeal cancer and EBV-positive Hodgkin's disease. Vaccination with the LMP-2:340-349 peptide may boost the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against LMP-2 producing cells, resulting in cell lysis and inhibition of cancer cell proliferation" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5466" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/482" ; obo:OGG_0000000006 "5689" ; obo:VO_0001818 "5466" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PSMB9" ; rdfs:label "LMP-2:340-349 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005498, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9261 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007547 obo:IAO_0000115 "A peptide vaccine containing amino acids residues from 419 through 427 of the latent membrane protein-2 (LMP-2) of the Epstein-Barr virus (EBV) with potential immunostimulating and antineoplastic activities. LMP-2, an EBV transmembrane protein, is expressed in various malignancies including nasopharyngeal cancer and EBV-positive Hodgkin's disease. Vaccination with the LMP-2:49-427 peptide may boost the immune system to mount a specific cytotoxic T-lymphocyte response against LMP-2 producing cells, resulting in cell lysis and inhibition of cancer cell proliferation." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5479" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/483" ; obo:OGG_0000000006 "5689" ; obo:VO_0001818 "5479" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PSMB9" ; rdfs:label "LMP-2:419-427 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005498, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9261 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007548 obo:IAO_0000115 "A cancer vaccine comprised of synthetic peptides derived from human melanoma antigen A1 (MAGE-A1), human melanoma antigen A3 (MAGE-A3) and cancer-testis antigen NY-ESO-1 with potential immunostimulating and antineoplastic activities. Upon administration, MAGE-A1/MAGE-A3/NY-ESO-1 peptides vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing MAGE-A1, MAGE-A3 and NY-ESO-1, resulting in tumor cell lysis. The MAGE-A1, MAGE-A3, and NY-ESO-1 tumor-associated antigens (TAAS) are overexpressed by a variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5263" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/490" ; obo:OGG_0000000006 "4100", "4102" ; obo:VO_0001818 "5263" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3|Gene name: MAGEA1" ; rdfs:label "MAGE-A1/MAGE-A3/NY-ESO-1 Peptides Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007549 obo:IAO_0000115 "A trivalent cancer vaccine containing the ganglioside lactones GM2, GD2 and GD3 conjugated with the immunostimulant keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. Vaccination with GM2 lactone/GD2 lactone/GD3 lactone-KLH conjugate trivalent vaccine may elicit antibodies against tumor cells expressing any of these epitopes, resulting in an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cells expressing these gangliosides. GM2, GD2 and GD3 are tumor associated antigens (TAAs) that are overexpressed in a variety of tumor cell membranes." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5532" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/178" ; obo:OGG_0000000006 "117189", "2760" ; obo:VO_0001818 "5532" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM2A|Gene name: GRDX" ; rdfs:label "GM2/GD2/GD3 Lactone-KLH Conjugate Trivalent Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007550 obo:IAO_0000115 "A cancer vaccine containing four HLA-A*2402-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Peptide epitopes in this vaccine are derived from ring finger protein 43 (RNF43); translocase of outer mitochondrial membrane 34 (TOMM34); and vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A*2404-restricted RNF43-TOMM34-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing RNF43, TOMM34, and VEGFR 1 and 2 peptides, resulting in tumor cell lysis and decreased tumor growth. HLA-A*2402 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*2402 may improve antigenic peptide immunogenicity" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5429" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/421" ; obo:OGG_0000000006 "10953", "3791" ; obo:VO_0001818 "5429" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KDR|Gene name: TOMM34" ; rdfs:label "HLA-A*2404-Restricted RNF43-TOMM34-VEGFR1-VEGFR2 Multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007551 obo:IAO_0000115 "A peptide vaccine comprised of synthetic HLA-A1, -A2 and -B35 restricted survivin epitopes combined with the adjuvant Montanide ISA-51 with potential antineoplastic activity. Upon administration, HLA-A1, A2, B35-restricted survivin peptides/Montanide ISA-51 vaccine may stimulate a cytotoxic T cell response against tumor cells that overexpress survivin, resulting in tumor cell lysis. Montanide ISA-51, also known as incomplete Freund's adjuvant or IFA, is a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant that non-specifically stimulates cell-mediated immune responses to antigens." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5120" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/422" ; obo:VO_0001818 "5120" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Survivin" ; rdfs:label "HLA-A1, A2, B35-Restricted Survivin Peptides/Montanide ISA-51 Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007552 obo:IAO_0000115 "A dendritic cell (DC) vaccine containing ex vivo expanded autologous DCs obtained from a patient with leukemia with potential immunostimulating activity. Upon reintroduction into the host, the host dendritic cell vaccine-001 MSSM/BIIR may stimulate the immune system to mount a leukemia-specific cytotoxic T lymphocyte (CTL) response." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5246" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/428" ; obo:OGG_0000000006 "1489078" ; obo:VO_0001818 "5246" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: E6" ; rdfs:label "Host Dendritic Cell Vaccine-001 MSSM/BIIR" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007553 obo:IAO_0000115 "A multi-peptide cancer vaccine with potential immunostimulating and antineoplastic activities. IMT-1012 immunotherapeutic vaccine contains twelve different synthetic peptides or tumor associated antigens (TAAs), including cyclin I (CCNI), cyclin-dependent kinase CDC2, EDDRI and TACE/ADAM17, each of which is involved in a different pathway associated with tumor growth, survival, and metastasis. Each antigen in the vaccine elicits a specific cytotoxic T-lymphocyte (CTL) immune response against tumor cells expressing that antigen. This multi-antigen/multi-pathway targeting strategy provides broad immunotherapeutic coverage with respect to tumor complexity and heterogeneity and may result in enhanced vaccine efficacy." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5048" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/464" ; obo:OGG_0000000006 "10983", "983" ; obo:VO_0001818 "5048" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: CDK1|Gene name: CCNI" ; rdfs:label "IMT-1012 Immunotherapeutic Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007554 obo:IAO_0000115 "A cancer vaccine containing four HLA-A0201-restricted peptide epitopes with potential immunostimulatory and antitumor activities. Vaccine peptide epitopes are derived from the tumor associated antigens (TAAs) tyrosinase-related protein 2 (TRP2), glycoprotein 100 (gp100), Ephrin receptor A2 (EphA2) and human epidermal growth factor receptor 2 (HER2). Upon administration, HLA-A0201-restricted TRp2-gp100-EphA2-HER2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against TRP2-gp100-EphA2-HER2-expressing tumor cells, resulting in tumor cell lysis and decreased tumor cell proliferation. HLA-A0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5355" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/309" ; obo:OGG_0000000006 "2064", "6490" ; obo:VO_0001818 "5355" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: PMEL|Gene name: ERBB2" ; rdfs:label "HLA-A0201-Restricted TRP2-gp100-EphA2-HER2 multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007555 obo:IAO_0000115 "A cancer vaccine containing three HLA-A0201-restricted peptide epitopes with potential immunostimulatory, antiangiogenic, and antitumor activities. Vaccine peptide epitopes are derived from the tumor associated antigen (TAA) URLC (up-regulated in lung cancer 10) and vascular endothelial growth factor receptors (VEGFR) 1 and 2. Upon administration, HLA-A0201-restricted URLC10-VEGFR1-VEGFR2 multipeptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against URLC10-expressing tumor cells and the tumor microvasculature expressing VEGFR 1 and 2 peptides; this may result in tumor cell lysis, the inhibition of tumor angiogenesis, and decreased tumor growth. HLA-A0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5017" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/417" ; obo:OGG_0000000006 "3791", "54742" ; obo:VO_0001818 "5017" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KDR|Gene name: LY6K" ; rdfs:label "HLA-A*0201-Restricted URLC10-VEGFR1-VEGFR2 Multipeptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007556 obo:IAO_0000115 "A live-attenuated, double-deleted strain of the Gram-positive bacterium Listeria monocytogenes (Lm) encoding a mutant form of the tumor associated antigens, epidermal growth factor receptor (EGFRvIII) and the cancer/testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, live-attenuated Listeria monocytogenes encoding EGFRvIII-NY-ESO-1 vaccine targets dendritic cells and expresses EGFRvIII and NY-ESO-1. This promotes both a potent innate immune response and an adaptive immune response involving the recruitment and activation of T lymphocytes against EGFRvIII and NY-ESO-1-expressing tumor cells, which results in tumor cell lysis." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4991" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/480" ; obo:OGG_0000000006 "1485", "1956" ; obo:VO_0001818 "4991" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: EGFR|Gene name: CTAG1B" ; rdfs:label "Live-attenuated Listeria monocytogenes-encoding EGFRvIII-NY-ESO-1 Vaccine ADU-623" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007557 obo:IAO_0000115 "A multivalent vaccine comprised of the epitope antigens of Globo H hexasaccharide 1 (Globo H), GM2 ganglioside, Lewis-Y, MUC1-32-mer, TF(c), and Tn(c) conjugated with keyhole limpet hemocyanin, with potential antineoplastic activity. The antigens included in this vaccine are associated various cancer cells. Vaccination with this multivalent vaccine may induce production of IgG and IgM antibodies as well as an antibody-dependent cell-mediated cytotoxicity (ADCC) against tumors expressing these antigens." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5104" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/173" ; obo:OGG_0000000006 " 4582", "2760" ; obo:VO_0001818 "5104" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: GM2A|Gene name: MUC1" ; rdfs:label "Globo H-GM2-Lewis-y-MUC1-32-mer-TF(c)-Tn(c)-KLH Conjugate Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007558 obo:IAO_0000115 "Peripheral blood lymphocytes (PBL) transfected to express MOv have been designed for possible use in autologous adoptive cellular immunotherapy of ovarian adenocarcinomas that overexpress folate-binding protein. MOv-PBLs express MOv-gamma (MOv), a chimeric receptor gene product derived from a recombinant gene encoding the variable region of murine monoclonal antibody MOv18 against folate-binding protein (FBP), often overexpressed in human ovarian cancer cells, and the human gene encoding the IgG and IgE Fc receptor gamma subunit. Autologous vaccination with these PBLs stimulates a host cytotoxic T lymphocyte response against ovarian cancer cells that overexpress FBP." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5335" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/541" ; obo:OGG_0000000006 "4343" ; obo:VO_0001818 "5335" ; a owl:Class ; rdfs:comment "Gene name: MOV10" ; rdfs:label "MOv-PBL Vaccine" ; rdfs:subClassOf obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ] . obo:VO_0007559 obo:IAO_0000115 "An attenuated oncolytic vaccinia virus encoding the light-emitting fusion protein Renilla luciferase-Aequorea green fluorescent protein (RUC-GFP) with potential bioluminescent and antineoplastic activities. Upon administration, light-emitting oncolytic vaccinia virus GL-ONC1 specifically enters tumor cells due to the permeable nature of the tumor vasculature. Once inside the cell, the virus replicates, resulting in tumor cell lysis and the release of mature viral particles into the tumor microenvironment. Released viral particles may then infect and destroy neighboring tumor cells. In addition, the release of tumor-associated antigens (TAAs) by lysed tumor cells into the bloodstream may activate the immune system to mount a cytotoxic T lymphocyte (CTL) response against the tumor. The expression of RUC-GFP by this agent allows for both detection and monitoring of virally infected tumor cells in vivo and vitro with luciferase-mediated bioluminescence imaging and fluorescence imaging techniques." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5385" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/477" ; obo:VO_0001818 "5385" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: Tumor Associated Antigen" ; rdfs:label "Light-Emitting Oncolytic Vaccinia Virus GL-ONC1 Vaccine" ; rdfs:subClassOf obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1964 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007560 obo:IAO_0000115 "A cancer vaccine containing an HLA-A*0201-restricted vascular endothelial growth factor receptor 1 (VEGFR1) peptide (sequence: TLFWLLLTL) with potential immunostimulatory and antitumor activities. Upon administration, HLA-A*0201-restricted VEGFR1-derived peptide vaccine may stimulate a cytotoxic T lymphocyte (CTL) response against tumor cells expressing VEGFR1, resulting in tumor cell lysis and decreased tumor growth. HLA-A*0201 is an MHC class I molecule that presents antigenic peptides to CD8+ T cells; epitope design restricted to epitopes that bind most efficiently to HLA-A*0201 may improve antigenic peptide immunogenicity." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5413" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/418" ; obo:OGG_0000000006 "3791" ; obo:VO_0001818 "5413" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KDR" ; rdfs:label "HLA-A*0201-Restricted VEGFR1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005430, obo:VO_0005484, obo:VO_0005489, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1993 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_219 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_9256 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007561 obo:IAO_0000115 "A cancer vaccine consisting of a recombinant fowlpox virus encoding human prostate-specific antigen (PSA) and TRICOM, a combination of three immunostimulants (i.e., B7.1, ICAM-1, and LFA-3). Administration of this agent may induce a cytotoxic T cell response against PSA-expressing tumor cells. Dendritic cells infected with TRICOM vectors greatly enhance naive T-cell activation and peptide-specific T-cell stimulation. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it is replication incompetent in mammalian cells." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5038" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/132" ; obo:OGG_0000000006 "354" ; obo:VO_0001818 "5038" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: KLK3" ; rdfs:label "Fowlpox-PSA-TRICOM Vaccine" ; rdfs:subClassOf obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007562 obo:IAO_0000115 "A prostate cancer vaccine containing mRNAs encoding prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), prostate stem cell antigen (PSCA) and six-transmembrane epithelial antigen of the prostate (STEAP), with potential antitumor activity. Upon administration, mRNA-derived prostate cancer vaccine CV9103 may stimulate the immune system to mount a cytotoxic T lymphocyte response (CTL) against PSA-, PSMA-, PSCA- and STEAP-expressing prostate tumor cells. The mRNA used in this vaccine is modified and formulated to have enhanced translational potency and adjuvant activities. PSA, PSMA, PSCA and STEAP may be upregulated in prostate cancer cells; their expression in prostate cancer has been correlated with disease progression." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5369" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/542" ; obo:OGG_0000000006 "26872" ; obo:VO_0001818 "5369" ; a owl:Class ; rdfs:comment "Gene name: STEAP1" ; rdfs:label "mRNA-Derived Prostate Cancer Vaccine CV9103" ; rdfs:subClassOf obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0007563 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5126" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/546" ; obo:OGG_0000000006 "4583" ; obo:VO_0001818 "5126" ; a owl:Class ; rdfs:comment "Gene name: MUC2" ; rdfs:label "MUC-2-Globo H-KLH Conjugate Vaccine" ; rdfs:subClassOf obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0007564 obo:IAO_0000115 "A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/194" ; obo:OGG_0000000006 "7124" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TNF" ; rdfs:label "Golnerminogene Pradenovec Vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0005425, obo:VO_0005426, obo:VO_0005430, obo:VO_0005496, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1793 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1993 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_5041 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007565 obo:IAO_0000115 "A peptide vaccine comprised of synthetic HLA-A2- and HLA-A3-binding peptides, derived from amino acid sequences of fibroblast growth factor-5 (FGF-5), combined with the adjuvant Montanide ISA-51 with potential antineoplastic activity. HLA-A2, A3-restricted FGF-5 peptides contain motifs recognized by the MHC class I molecules HLA-A2 and HLA-A3 and may stimulate a cytotoxic T-cell response against tumor cells that overexpress FGF-5. Montanide ISA-51, a stabilized water-in-oil emulsion adjuvant containing mineral oil with mannide oleate added as a surfactant, non-specifically stimulates cell-mediated immune responses to antigens" ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5465" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/424" ; obo:OGG_0000000006 "2250" ; obo:VO_0001818 "5465" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: FGF5" ; rdfs:label "HLA-A2, A3-Restricted FGF-5 Peptides/Montanide ISA-51 Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007566 obo:IAO_0000115 "A naturally occurring 9-residue peptide of fibroblast growth factor 5 (FGF-5). Recognized by tumor infiltrating cytotoxic T lymphocytes originally isolated from a renal cell carcinoma that overexpressed FGF-5, FGF-5:172-176/217-220 peptide activates various cytotoxic CD8 lymphocytes in an HLA-restricted manner. Overexpressed in several cancer cell lines, FGF-5 is a tumor-associated antigen that may be useful in cancer immunotherapy." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5498" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/134" ; obo:OGG_0000000006 "4108" ; obo:VO_0001818 "5498" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MAGEA9" ; rdfs:label "G250 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007567 obo:IAO_0000115 "A synthetic peptide derived from the protein ESW/FLI1 type 1 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-1 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 1 fusion protein." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5509" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/52" ; obo:OGG_0000000006 " 253970502", "100306940" ; obo:VO_0001818 "5509" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: FL1|Gene name: EWSR1" ; rdfs:label "EF-1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005495, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1115 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007568 obo:IAO_0000115 "A cancer vaccine comprised of a 43 amino acid epitope from glycoprotein MUC1 (mucin 1) and the synthetic Toll-like receptor 4 (TLR-4) agonist PET lipid A encapsulated in cholesterol/dipalmitoylphosphatidylcholine (DPPC)/dimyristoylphosphatidylglycerol (DMPG) liposomes, with potential immunostimulatory and antineoplastic activities. The MUC1 epitope is composed of two 20 amino glycosylated VNTR (various number tandem repeats) from human MUC1A and including 6 glycosylated sites modified by Tn (alfa-N-acetyl-D-galactosamine). Immunization of liposomal MUC1/PET-lipid A vaccine results in an antibody as well as a cytotoxic T-lymphocyte (CTL) response against hypoglycosylated MUC1 expressing tumor cells. The tumor associated antigen MUC1, a type I transmembrane protein, is overexpressed and aberrantly glycosylated in a variety of tumor cells. As a vaccine adjuvant, PET lipid A, also known as penta erythritol lipid A, stimulates both cellular and humoral responses to the vaccine antigen." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5488" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/479" ; obo:OGG_0000000006 "4582" ; obo:VO_0001818 "5488" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: MUC1" ; rdfs:label "Liposomal MUC1/PET-lipid A Vaccine" ; rdfs:subClassOf obo:VO_0005484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007569 obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5345" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/493" ; obo:OGG_0000000006 "4102" ; obo:VO_0001818 "5345" ; a owl:Class ; rdfs:comment "Gene name: MAGEA3" ; rdfs:label "MAGE-A3/HPV 16 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007570 obo:IAO_0000115 "A peptide derived from the tumor suppressor protein Von Hippel-Lindau (VHL). This peptide, sequence: MEAGRPRPCCAR, was constructed based on a frameshift mutation of one of the VHL gene products; the more abundant protein VHLp18(MEA) (where MEA stands for three amino acids, Met-Glu-Ala). Vaccination with FrSh61(MEA)VHL33 peptide may stimulate a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing this VHL mutant protein." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5236" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/133" ; obo:OGG_0000000006 "7428" ; obo:VO_0001818 "5236" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VHL" ; rdfs:label "FrSh61 (MEA) VHL33 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005494, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_263 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007571 obo:IAO_0000115 "A cancer vaccine based on virus-like replicon particles (VRP) packaged with an alphaviral vector encoding the extracellular domain (ECD) and transmembrane (TM) regions of the human epidermal growth factor receptor 2 (EGFR2, NEU or HER2), with potential antineoplastic activity. After immunization with HER2 ECD+TM virus-like replicon particles vaccine AVX901, the VRPs infect cells and express HER2 ECD+TM protein that may activate the immune system to elicit a cytotoxic T-lymphocyte (CTL) response against HER2-expressing tumor cells. The alphaviral replicon of this vaccine is an attenuated strain of the Venezuelan equine encephalitis virus (VEEV) in which 3 of the 7 viral genes were substituted with a truncated HER2 gene to create a self-amplifying replicon RNA. HER2, a tyrosine kinase involved in several cell growth signaling pathways, is dysregulated or overexpressed in a wide variety of cancer cell types." ; obo:IAO_0000117 "Jie Zheng", "Justin Song", "Oliver He", "Penny Pan" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5442" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/305" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "5442" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "HER2 ECD+TM Virus-like Replicon Particles Vaccine AVX901" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0007572 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5303" ; obo:VO_0001818 "5303" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Ad5-yCD/mutTKSR39rep-hIL12 vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007573 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5324" ; obo:VO_0001818 "5324" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Ad5F35-LMP1/LMP2-Transduced Autologous Dendritic Cell vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007574 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5534" ; obo:VO_0001818 "5534" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Alpha Fetoprotein Plasmid DNA Vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007575 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4995" ; obo:VO_0001818 "4995" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "ALVAC-CEA (6D)-B7.1 Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007576 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5085" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0007283 ; a owl:Class ; rdfs:label "obsolete Autologous Dendritic Cell Vaccine ACT2001" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0007577 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0007289 ; a owl:Class ; rdfs:label "obsolete Autologous Dendritic Cell-Tumor Fusion Vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0007578 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4051" ; obo:VO_0001818 "4051" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "autologous dendritic cells (DCs) vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007579 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0007301 ; a owl:Class ; rdfs:label "obsolete Autologous Immunoglobulin Idiotype-KLH Conjugate Vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0007580 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3981" ; obo:VO_0001818 "3981" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "autologous monocyte-derived mature DCs pulsed with p53, survivin and telomerase-derived peptide vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007581 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4029" ; obo:VO_0001818 "4029" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Bacille Calmette Guerin for melanoma of lower extremity vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007582 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4028" ; obo:VO_0001818 "4028" ; obo:VO_0005500 "Licensed" ; a owl:Class ; rdfs:label "Bacillus Calmette-Guerin (BCG) vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007583 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4036" ; obo:VO_0001818 "4036" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Bacillus Calmette-Guerin (BCG), C. parvum vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007584 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4035" ; obo:VO_0001818 "4035" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Bacillus Calmette-Guerin (BCG), dinitrochlorobenzene (DNCB) vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007585 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4034" ; obo:VO_0001818 "4034" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "bacillus Calmette-Guerin (MER) vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007586 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4021" ; obo:VO_0001818 "4021" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "BCG and chemotherapy for malignant melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007587 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4022" ; obo:VO_0001818 "4022" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "BCG and Corynebacterium parvum for malignant melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007588 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4033" ; obo:VO_0001818 "4033" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "BCG treatment after surgical tumor removal vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007589 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5399" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0007328 ; a owl:Class ; rdfs:label "obsolete Bcl-Xs Adenovirus Vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0007590 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4017" ; obo:VO_0001818 "4017" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Biolistic DNA vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007591 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3984" ; obo:VO_0001818 "3984" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Canvaxin" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007592 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5476" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0007358 ; a owl:Class ; rdfs:label "obsolete CD80 Breast Cancer Vaccine" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0007593 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4072" ; obo:VO_0001818 "4072" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "class I HLA-A0201-restricted gp100209-2M peptide vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007594 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5456" ; obo:VO_0001818 "5456" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Contusugene ladenovec vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007595 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3990" ; obo:VO_0001818 "3990" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "CpG 7909/PF3512676 vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007596 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4170" ; obo:VO_0001818 "4170" ; obo:VO_0005500 "Licensed" ; a owl:Class ; rdfs:label "CVB4/p24(73(3)) vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007597 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5494" ; obo:VO_0001818 "5494" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Dendritic Cell-Idiotype-Keyhole Limpet Hemocyanin Vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007598 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5346" ; obo:VO_0001818 "5346" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "DEPDC1/MPHOSH1 Peptide Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005485, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_11054 ] . obo:VO_0007599 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5116" ; obo:VO_0001818 "5116" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "DLK1/EPHA2/HBB/NRP1/RGS5/TEM1 Peptide-pulsed Alpha-type-1 Polarized Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007600 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4060" ; obo:VO_0001818 "4060" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "DNA Vaccine encoding p42.3" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007601 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3998" ; obo:VO_0001818 "3998" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "DNP-modified autologous vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007602 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4076" ; obo:VO_0001818 "4076" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "electroloading of mature dendritic cells with melanoma whole tumor cell lysate vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007603 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4067" ; obo:VO_0001818 "4067" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "ESAT-6-gpi DNA vaccine combined with B16F10-ESAT-6-gpi/IL-21 vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007604 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4081" ; obo:VO_0001818 "4081" ; obo:VO_0005500 "Research" ; 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obo:VO_0001818 "3996" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Melacine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007641 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3985" ; obo:VO_0001818 "3985" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Melan-A/Mart-1 vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007642 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3979" ; obo:VO_0001818 "3979" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Melanoma-specific Melan-A/Mart-1 peptide + virus-like nanoparticles" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007643 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5412" ; obo:VO_0001818 "5412" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Modified Vaccinia Virus Ankara Vaccine Expressing p53" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007644 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4068" ; obo:VO_0001818 "4068" ; obo:VO_0005500 "Licensed" ; a owl:Class ; rdfs:label "mouse/human gp10025-33 peptide plus CpG adjuvant; mouse/human gp100; mouse/human gp10025-33 peptide-pulsed DCs vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007645 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=5224" ; obo:VO_0001818 "5224" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Multi-epitope Folate Receptor Alpha-loaded Dendritic Cell Vaccine" ; rdfs:subClassOf obo:VO_0005484, obo:VO_0005493, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_2394 ] . obo:VO_0007646 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4063" ; obo:VO_0001818 "4063" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "Multipeptide melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007647 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4030" ; obo:VO_0001818 "4030" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Oral Bacille Calmette-Guerin for malignant melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007648 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=3983" ; obo:VO_0001818 "3983" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "OVA-TEXO vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007649 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4032" ; obo:VO_0001818 "4032" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:label "procarbazine, dactinomycin, velba vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007650 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4031" ; obo:VO_0001818 "4031" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "Pulmonary BCG immunotherapy for malignant melanoma vaccine" ; rdfs:subClassOf obo:VO_0000422, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1909 ] . obo:VO_0007651 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=6075" ; obo:VO_0001818 "6075" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "RIPO(H3.3) vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007652 obo:IAO_0000117 "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=4011" ; obo:VO_0001818 "4011" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "alpha-GalCer-loaded tumor-cell vaccine" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0007653 obo:IAO_0000115 "A cancer that is caused by human papillomavirus (HPV). HPV can cause six types of cancer including anal cancer, cervical cancer, oropharyngeal cancer, penile cancer, vaginal cancer, and vulvar cancer." ; obo:IAO_0000116 "placeholder, will send new term requst to DOID" ; obo:IAO_0000117 "Jie Zheng, Xingxian Li" ; oboInOwl:inSubset "disposition" ; a owl:Class ; rdfs:label "HPV associated cancer" ; rdfs:subClassOf obo:DOID_162 . obo:VO_0010000 obo:IAO_0000115 "A Cp12 protein that is part of Crptosporidium parvum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Crptosporidium parvum Cp12" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010842, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010001 obo:IAO_0000115 "A Cp21 protein that is part of Crptosporidium parvum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Crptosporidium parvum Cp21" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010842, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010002 obo:IAO_0000115 "A Cp15 protein that is part of Crptosporidium parvum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Crptosporidium parvum Cp15" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010842, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010003 obo:IAO_0000115 "A CP60 protein that is part of Crptosporidium parvum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Crptosporidium parvum CP60" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010842, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010004 obo:IAO_0000115 "A Cp23 protein that is part of Crptosporidium parvum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Crptosporidium parvum Cp23" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010842, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010005 obo:IAO_0000115 "A CpP2 protein that is part of Crptosporidium parvum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Crptosporidium parvum CpP2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010842, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010006 obo:IAO_0000115 "A 3-1E protein that is part of Eimeria acervulina" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Eimeria acervulina 3-1E" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010822, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010007 obo:IAO_0000115 "A gam56 protein that is part of Eimeria maxima" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Eimeria maxima gam56" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010833, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010009 obo:IAO_0000115 "A a1-giardin protein that is part of Giardia duodenalis" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Giardia duodenalis a1-giardin" ; rdfs:seeAlso "NCBI Gene ID 5697168" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010829, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010010 obo:IAO_0000115 "A a1-giardin protein that is part of Giardia lamblia" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Giardia lamblia a1-giardin" ; rdfs:seeAlso "NCBI Gene ID 5697168" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015483, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010011 obo:IAO_0000115 "A alpha-enolase protein that is part of Giardia lamblia" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Giardia lamblia alpha-enolase" ; rdfs:seeAlso "NCBI Gene ID 2023" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015483, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010012 obo:IAO_0000115 "A CWP2 protein that is part of Giardia lamblia" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Giardia lamblia CWP2" ; rdfs:seeAlso "NCBI Gene ID 5703171" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015483, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010013 obo:IAO_0000115 "A Acen1 protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani Acen1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010014 obo:IAO_0000115 "A Beta-tubulin protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani Beta-tubulin" ; rdfs:seeAlso "NCBI Gene ID 13392307" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010015 obo:IAO_0000115 "A FML protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani FML" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010016 obo:IAO_0000115 "A Gp63 protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani Gp63" ; rdfs:seeAlso "NCBI Gene ID 13389283" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010017 obo:IAO_0000115 "A HASPB1 protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani HASPB1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010018 obo:IAO_0000115 "A KH protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani KH" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010019 obo:IAO_0000115 "A LdyGCS protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani LdyGCS" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010020 obo:IAO_0000115 "A NH36 protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani NH36" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010021 obo:IAO_0000115 "A P1 protein that is part of Leishmania donovani" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani P1" ; rdfs:seeAlso "NCBI Gene ID 13388831" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010022 obo:IAO_0000115 "A A2 protein that is part of Leishmania infantum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania infantum A2" ; rdfs:seeAlso "NCBI Gene ID 13387764" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010836, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010023 obo:IAO_0000115 "A HSP70 II protein that is part of Leishmania infantum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania infantum HSP70 II" ; rdfs:seeAlso "NCBI Gene ID 5073319" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010836, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010024 obo:IAO_0000115 "A KMP-11 protein that is part of Leishmania major" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania major KMP-11" ; rdfs:seeAlso "NCBI Gene ID 13387683" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010025 obo:IAO_0000115 "A LmSTI1 protein that is part of Leishmania major" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania major LmSTI1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010026 obo:IAO_0000115 "A LIPO-A protein that is part of Leishmania major" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania major LIPO-A" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010027 obo:IAO_0000115 "A P36 protein that is part of Leishmania major" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania major P36" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010028 obo:IAO_0000115 "A PEPCK protein that is part of Leishmania major" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania major PEPCK" ; rdfs:seeAlso "NCBI Gene ID 5649768" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010029 obo:IAO_0000115 "A LeIF protein that is part of Leishmania major" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania major LeIF" ; rdfs:seeAlso "NCBI Gene ID 12981542" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010030 obo:IAO_0000115 "A MIC3 protein that is part of Neospora caninum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum MIC3" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0010031 obo:IAO_0000115 "A GRA2 protein that is part of Neospora caninum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum GRA2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0010032 obo:IAO_0000115 "A GRA6 protein that is part of Neospora caninum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum GRA6" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0010033 obo:IAO_0000115 "A SRS2 protein that is part of Neospora caninum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum SRS2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010034 obo:IAO_0000115 "A MIC10 protein that is part of Neospora caninum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum MIC10" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010035 obo:IAO_0000115 "A p24 protein that is part of Neospora caninum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum p24" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0010036 obo:IAO_0000115 "A PDI protein that is part of Neospora caninum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum PDI" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0010037 obo:IAO_0000115 "A SAG1 protein that is part of Neospora caninum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum SAG1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010039 obo:IAO_0000115 "A P36p protein that is part of Plasmodium berghei" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium berghei P36p" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015475, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010040 obo:IAO_0000115 "A ABRA protein that is part of Plasmodium falciparum|An ABRA protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum ABRA" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000137 ] . obo:VO_0010041 obo:IAO_0000115 "A EBA-175 RII protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum EBA-175 RII" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010042 obo:IAO_0000115 "A Hsp90 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum Hsp90" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010043 obo:IAO_0000115 "A MSP1 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum MSP1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000130 ] . obo:VO_0010044 obo:IAO_0000115 "A RESA protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum RESA" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000130 ] . obo:VO_0010045 obo:IAO_0000115 "A MSP2 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum MSP2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000130 ] . obo:VO_0010046 obo:IAO_0000115 "A MSP4 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum MSP4" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000130 ] . obo:VO_0010047 obo:IAO_0000115 "A Pf ribosomal protein P0 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum Pf ribosomal protein P0" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000242 ] . obo:VO_0010048 obo:IAO_0000115 "A PfCelTOS protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum PfCelTOS" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010049 obo:IAO_0000115 "A PfSSP2 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum PfSSP2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000137 ] . obo:VO_0010050 obo:IAO_0000115 "A LSA1 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum LSA1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010051 obo:IAO_0000115 "A Pfen protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum Pfen" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000242 ] . obo:VO_0010052 obo:IAO_0000115 "A Pfs230 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum Pfs230" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000258 ] . obo:VO_0010053 obo:IAO_0000115 "A Pfs25 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum Pfs25" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000258 ] . obo:VO_0010054 obo:IAO_0000115 "A Pfs48 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum Pfs48" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000258 ] . obo:VO_0010055 obo:IAO_0000115 "A RH5 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum RH5" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000130 ] . obo:VO_0010056 obo:IAO_0000115 "A TRAP protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum TRAP" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010057 obo:IAO_0000115 "A Pfs45 protein that is part of Plasmodium falciparum" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum Pfs45" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000258 ] . obo:VO_0010058 obo:IAO_0000115 "A PkCSP protein that is part of Plasmodium knowlesi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium knowlesi PkCSP" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015472, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000393 ] . obo:VO_0010059 obo:IAO_0000115 "A PkSSP2 protein that is part of Plasmodium knowlesi|A SSP2 protein that is part of Plasmodium knowlesi" ; obo:IAO_0000117 "Anthony Huffman" ; obo:IAO_0000118 "Plasmodium vivax Thrombospondin-related apical merozoite protein" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium knowlesi SSP2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015472, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010060 obo:IAO_0000115 "A PkAMA1 protein that is part of Plasmodium knowlesi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium knowlesi PkAMA1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015472, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000393 ] . obo:VO_0010061 obo:IAO_0000115 "A PkMSP1 protein that is part of Plasmodium knowlesi|A PkMSP1p42 protein that is part of Plasmodium knowlesi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium knowlesi PkMSP1p42" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015472, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000394 ] . obo:VO_0010062 obo:IAO_0000115 "A CelTOS protein that is part of Plasmodium vivax|A PvCelTOS protein that is part of Plasmodium vivax" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium vivax CelTOS" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000327 ] . obo:VO_0010063 obo:IAO_0000115 "A CS protein that is part of Plasmodium vivax|A PvCS protein that is part of Plasmodium vivax" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium vivax CS" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000327 ] . obo:VO_0010064 obo:IAO_0000115 "A DBPII protein that is part of Plasmodium vivax|A PvDBPII protein that is part of Plasmodium vivax" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium vivax PvDBPII" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000328 ] . obo:VO_0010065 obo:IAO_0000115 "A TRAP protein that is part of Plasmodium vivax" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium vivax TRAP" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000327 ] . obo:VO_0010066 obo:IAO_0000115 "A HEP17 protein that is part of Plasmodium yoelii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium yoelii HEP17" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010067 obo:IAO_0000115 "A HSP60 protein that is part of Plasmodium yoelii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "PMC98419 citation for occurance in all lifestages" ; rdfs:label "Plasmodium yoelii HSP60" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000385 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000386 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000387 ] . obo:VO_0010068 obo:IAO_0000115 "A SSP2 protein that is part of Plasmodium yoelii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium yoelii SSP2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000385 ] . obo:VO_0010069 obo:IAO_0000115 "A ASP-1 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi ASP-1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010070 obo:IAO_0000115 "A CRP protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi CRP" ; rdfs:seeAlso "NCBI Gene ID 947867" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010071 obo:IAO_0000115 "A G1 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi G1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010072 obo:IAO_0000115 "A PAR3 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi PAR3" ; rdfs:seeAlso "NCBI Gene ID 3540497" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010073 obo:IAO_0000115 "A PFR Ag protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi PFR Ag" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010074 obo:IAO_0000115 "A rTcENO from H8 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi rTcENO from H8" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010075 obo:IAO_0000115 "A Tc24 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi Tc24" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010076 obo:IAO_0000115 "A Tc80 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi Tc80" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010077 obo:IAO_0000115 "A TcENO protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi TcENO" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010078 obo:IAO_0000115 "A TcSSP4 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi TcSSP4" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010079 obo:IAO_0000115 "A TcTASV-C protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi TcTASV-C" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010080 obo:IAO_0000115 "A TCTS-154 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi TCTS-154" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010081 obo:IAO_0000115 "A Trans-salidase protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi Trans-salidase" ; rdfs:seeAlso "NCBI Gene ID 3537653" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010082 obo:IAO_0000115 "A TSA-1 protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi TSA-1" ; rdfs:seeAlso "NCBI Gene ID 3544076" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010083 obo:IAO_0000115 "A TsF protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi TsF" ; rdfs:seeAlso "NCBI Gene ID 3537653" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010084 obo:IAO_0000115 "A TSSA protein that is part of Trypanosoma cruzi" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi TSSA" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0010085 obo:IAO_0000115 "A CDPK1 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii CDPK1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010086 obo:IAO_0000115 "A CDPK6 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii CDPK6" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010087 obo:IAO_0000115 "A ROP18 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii ROP18" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010088 obo:IAO_0000115 "A CST2 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii CST2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010089 obo:IAO_0000115 "A CyP protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii CyP" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010091 obo:IAO_0000115 "A GRA1 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010092 obo:IAO_0000115 "A GRA16 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA16" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010093 obo:IAO_0000115 "A GRA17 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA17" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010094 obo:IAO_0000115 "A GRA24 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA24" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010095 obo:IAO_0000115 "A GRA23 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA23" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010096 obo:IAO_0000115 "A GRA25 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA25" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010097 obo:IAO_0000115 "A GRA41 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA41" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010098 obo:IAO_0000115 "A GRA6 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA6" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010099 obo:IAO_0000115 "A GRA7 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA7" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010100 obo:IAO_0000115 "A GRA8 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii GRA8" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010101 obo:IAO_0000115 "A hsp70 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii hsp70" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010102 obo:IAO_0000115 "A ISP3 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii ISP3" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010103 obo:IAO_0000115 "A MIC1 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii MIC1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010104 obo:IAO_0000115 "A MIC11 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii MIC11" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010105 obo:IAO_0000115 "A MIC13 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii MIC13" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010106 obo:IAO_0000115 "A MIC4 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii MIC4" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010107 obo:IAO_0000115 "A MIC6 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii MIC6" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010108 obo:IAO_0000115 "A MIC8 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii MIC8" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010109 obo:IAO_0000115 "A PGAM2 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii PGAM2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010110 obo:IAO_0000115 "A RACK1 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii RACK1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010111 obo:IAO_0000115 "A ROP16 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii ROP16" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010112 obo:IAO_0000115 "A ROP17 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii ROP17" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010114 obo:IAO_0000115 "A PLP1 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii PLP1" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010115 obo:IAO_0000115 "A ROP38 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii ROP38" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010116 obo:IAO_0000115 "A ROP8 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii ROP8" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010118 obo:IAO_0000115 "A ROP2 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii ROP2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010119 obo:IAO_0000115 "A SAG2 protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii SAG2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010120 obo:IAO_0000115 "A SAG5B protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii SAG5B" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010121 obo:IAO_0000115 "A SAG5C protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii SAG5C" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010122 obo:IAO_0000115 "A TgADF protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii TgADF" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010123 obo:IAO_0000115 "A TgNTPase-II protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii TgNTPase-II" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010124 obo:IAO_0000115 "A TgPF protein that is part of Toxoplasma gondii" ; obo:IAO_0000117 "Anthony Huffman" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii TgPF" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0010632 obo:IAO_0000117 "YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "country" ; rdfs:subClassOf obo:BFO_0000029 . obo:VO_0010633 obo:IAO_0000115 "USA is a country that exists in north America." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "site" ; a owl:Class ; rdfs:label "USA" ; rdfs:subClassOf obo:VO_0010632 . obo:VO_0010637 obo:IAO_0000115 "A viral vaccine that protects against infection with Rubella virus." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rubella virus vaccine" ; rdfs:seeAlso "MeSH: D012411" ; rdfs:subClassOf obo:VO_0003549, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11041 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11041 ] ) ] . obo:VO_0010702 obo:IAO_0000115 "A vaccine regulation for vaccine safety." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "vaccine saftey regulation" ; rdfs:subClassOf obo:VO_0000683 . obo:VO_0010704 obo:IAO_0000115 "A vaccine regulatory process that is for vaccine regulatory agent to review vaccine license application from vaccine producer." ; obo:IAO_0000117 "YH" ; oboInOwl:inSubset "process" ; a owl:Class ; rdfs:label "review of vaccine license application" ; rdfs:subClassOf obo:VO_0000683 . obo:VO_0010705 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Actacel" ; rdfs:label "Actacel" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0003168, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010706 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Avaxim" ; rdfs:label "Avaxim" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010707 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Avaxim - Pediatric" ; rdfs:label "Avaxim - Pediatric" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010708 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: BCG Vaccine (Freeze-Dried)" ; rdfs:label "BCG Vaccine (Freeze-Dried) (by Sanofi Pasteur)" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000771, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010709 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: DT Polio Adsorbed" ; rdfs:label "DT Polio Adsorbed" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010710 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Dukoral" ; rdfs:label "Dukoral" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000944, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000904 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:VO_0000908 ] . obo:VO_0010711 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/biologicsbloodvaccines/vaccines/approvedproducts/ucm110102.htm" ; obo:VO_0003099 "ENGERIX-B" ; obo:VO_0003158 "Hepatitis B Vaccine (Recombinant)" ; obo:VO_0003160 "ENGERIX-B is a vaccine indicated for immunization against infection caused by all known subtypes of hepatitis B virus." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM224503.pdf" ; obo:VO_0003162 "103239" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Engerix-B" ; rdfs:seeAlso "CVX: 08", "CVX: 44" ; rdfs:subClassOf obo:VO_0000644, obo:VO_0001485, obo:VO_0004914, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000940 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0004913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010712 obo:IAO_0000115 "A Measles-Rubella vaccine that is live attenuated and manufactured by GlaxoSmithKline Biologicals." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Eolarix" ; rdfs:label "Eolarix" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000367, obo:VO_0000945, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_52071 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000926 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010713 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Epaxal" ; rdfs:label "Epaxal" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000576 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000687 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010714 obo:IAO_0000116 """todo: assign parent immunogen: TBE""" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: FSME - IMMUN" ; rdfs:label "FSME - IMMUN" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000712, obo:VO_0012190, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000927 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000937 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_17833 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000912 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000916 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000895 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010715 obo:IAO_0000117 "Kallan Roan, Oliver He, ZX" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/683648", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm179527.htm" ; obo:VO_0003099 "HIBERIX" ; obo:VO_0003158 "Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)" ; obo:VO_0003160 "For active immunization for the prevention of invasive disease caused by Haemophilus influenzae type b. HIBERIX is approved for use in children 6 weeks through 4 years of age (prior to fifth birthday)." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM179530.pdf" ; obo:VO_0003198 "683648" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hiberix" ; rdfs:seeAlso "CVX: 48" ; rdfs:subClassOf obo:VO_0000195, obo:VO_0000662, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0015014 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000625 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010716 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Imovax Polio" ; rdfs:label "Imovax Polio" ; rdfs:subClassOf obo:VO_0000664, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000921 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_17076 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010717 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Imovax Rabies" ; rdfs:label "Imovax Rabies (Canada)" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000650, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000926 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010718 obo:IAO_0000115 "A poliovirus vaccine that contains inactivtated Poliomyelitis to prevent disease caused from the vaccine." ; obo:IAO_0000117 "Oliver He, Allen Xiang, Hector Guzman-Orozco" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Inactived Poliomyelitis Vaccine - IPV" ; rdfs:label "Inactivated Poliomyelitis Vaccine - IPV" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000664, obo:VO_0000712, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000921 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010719 obo:IAO_0000115 "A combination vaccine that protects infants from diphtheria, tetanus, pertussis (whooping cough), polio, hepatitis B and Haemophilus influenzae type b (Hib)." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000119 "http://www.immune.org.nz/vaccines/available-vaccines/infanrix-hexa" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Infanrix-hexa" ; rdfs:label "Infanrix-hexa" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000946, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000929 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000940 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010720 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Infanrix/Hib" ; rdfs:label "Infanrix/Hib" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0003168, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010721 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Infanrix-IPV" ; rdfs:label "Infanrix-IPV" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000742, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010722 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Infanrix -IPV/Hib" ; rdfs:label "Infanrix -IPV/Hib" ; rdfs:seeAlso "CVX: 120" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000744, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010723 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Liquid Pedvax HIB" ; rdfs:label "Liquid Pedvax HIB" ; rdfs:subClassOf obo:VO_0000662, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003049 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000695 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000896 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010724 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Meningitec" ; rdfs:label "Meningitec" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000687 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000905 ; owl:onProperty obo:VO_0000908 ] . obo:VO_0010725 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Meningococcal Polysaccharide Vaccine, Groups A & C, Menomune A/C" ; rdfs:label "Meningococcal Polysaccharide Vaccine, Groups A & C, Menomune A/C" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010726 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Menjugate" ; rdfs:label "Menjugate" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000696 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010727 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Menomune A/C/Y/W-135" ; rdfs:label "Menomune A/C/Y/W-135" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001256 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010728 obo:IAO_0000115 "A live attenuated V. cholerae vaccine that is manufactured by Berna Biotech, Ltd. This vaccine uses the V. Cholera strain CVD 103-HGR." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Mutacol" ; rdfs:label "Mutacol" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000763, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_2877 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000939 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000687 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010729 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Neisvac-C" ; rdfs:label "Neisvac-C" ; rdfs:subClassOf obo:VO_0000053, obo:VO_0000363, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000895 ; owl:onProperty obo:OBI_0000304 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:VO_0000908 ] . obo:VO_0010730 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Pediacel" ; rdfs:label "Pediacel" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000744, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000921 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_17076 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010731 obo:IAO_0000115 "A polyvalent pneumococcal vaccine used to protectsagainst serious infection (e.g., meningitis, bacteria in the blood) due to Streptococcus pneumoniae, and it is manufactured by Sanofi Pasteur." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "PNEUMO (PNU-IMUNE)", "Pnu-Imune", "Pnu-Imune 23" ; obo:IAO_0000119 "https://www.webmd.com/drugs/2/drug-5547/pnu-imune-injection/details" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Generic Name: pneumococcal vaccine polyvalent (Intramuscular route, Subcutaneous route)", "Trade Name: Pneumo 23" ; rdfs:label "Pneumo 23" ; rdfs:subClassOf obo:VO_0000424, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000888 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0001254 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010732 obo:IAO_0000117 "Allen Xiang", "Oliver He" ; a owl:Class ; rdfs:comment "Trade Name: Pneumovax 23" ; rdfs:label "obsolete Pneumovax 23 (Canada)" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0010733 obo:IAO_0000117 "Allen Xiang", "Oliver He" ; obo:IAO_0000119 "https://www.prevnar13.com/" ; a owl:Class ; rdfs:comment "Trade Name: Prevnar" ; rdfs:label "obsolete Prevnar (Canada)" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0010734 obo:IAO_0000115 "A MMR vaccine that is manufactured by GlaxoSmithKline Biologicals." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Priorix" ; rdfs:label "Priorix" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000367, obo:VO_0000731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010735 obo:IAO_0000115 "A Measles-Mumps-Rubella-Vericella vaccine that is live attenuated and manufactured by GlaxoSmithKline Biologicals. " ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Priorix-Tetra" ; rdfs:label "Priorix-Tetra" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000737, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010736 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1607804" ; obo:VO_0003198 "1607804" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Quadracel" ; rdfs:label "Quadracel" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000742, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000920 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000924 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003199 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003201 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003202 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003384 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003455 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003835 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003836 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003837 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010737 obo:IAO_0000117 "Kallan Roan, Oliver He" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm110098.htm" ; obo:VO_0003099 "RECOMBIVAX HB" ; obo:VO_0003158 "Hepatitis B Vaccine (Recombinant)" ; obo:VO_0003160 "RECOMBIVAX HB is indicated for vaccination against infection caused by all known subtypes of hepatitis B virus." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM110114.pdf" ; obo:VO_0003162 "BL 101066" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Recombivax HB" ; rdfs:seeAlso "CVX: 08", "CVX: 43", "CVX: 44" ; rdfs:subClassOf obo:VO_0000644, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000940 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000896 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010738 obo:IAO_0000116 """todo: assign parent immunogen: ROT""" ; obo:IAO_0000117 "Kallan Roan, Oliver He, ZX" ; obo:IAO_0000118 "ROTARIX" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm133920.htm" ; obo:VO_0003099 "Rotarix" ; obo:VO_0003158 "Rotavirus Vaccine, Live, Oral" ; obo:VO_0003160 "For the prevention of rotavirus gastroenteritis caused by G1 and non-G1 types (G3, G4, and G9), for use in infants 6 weeks to 24 weeks of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM133539.pdf" ; obo:VO_0003162 "BL 125265" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rotarix" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000367, obo:VO_0000658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_52071 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000934 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0004815 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0003021 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010739 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Td Adsorbed" ; rdfs:label "Td Adsorbed" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010742 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Tripacel" ; rdfs:label "Tripacel" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010743 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Twinrix Junior" ; rdfs:label "Twinrix Junior" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000745, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000929 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000940 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010744 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Typherix" ; rdfs:label "Typherix" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000671, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000888 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010745 obo:IAO_0000117 "Kallan Roan, Oliver He, ZX" ; obo:IAO_0000118 "VAQTA" ; obo:IAO_0000119 "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm110017.htm" ; obo:VO_0003099 "VAQTA" ; obo:VO_0003158 "Hepatitis A Vaccine, Inactivated" ; obo:VO_0003160 "For active immunization against disease caused by hepatitis A virus in persons 12 months of age and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM110049.pdf" ; obo:VO_0003162 "BL 103606" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Vaqta" ; rdfs:label "Vaqta" ; rdfs:subClassOf obo:VO_0000646, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000920 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000931 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000896 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010746 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Varilrix" ; rdfs:label "Varilrix" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000367, obo:VO_0000419, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000926 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000913 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010747 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Varivax III" ; rdfs:label "Varivax III" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000419, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16199 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17992 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000921 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000922 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000931 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000896 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010748 obo:IAO_0000116 "todo: assign parent immunogen: Typh-I + (HA)" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: ViVaxim" ; rdfs:label "ViVaxim" ; rdfs:subClassOf obo:VO_0000363, obo:VO_0000950, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16842 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000891 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000930 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:CHEBI_7507 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000699 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010749 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "Trade Name: Vivotif" ; rdfs:label "Vivotif (Canada)" ; rdfs:subClassOf obo:VO_0003353, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17716 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_2877 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000531 ; owl:someValuesFrom obo:VO_0000915 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000687 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0010751 obo:IAO_0000115 "a protein from a bacterium" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "bacterium protein" ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0010752 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "G+ bacterium protein" ; rdfs:subClassOf obo:VO_0010751 . obo:VO_0010753 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "G- bacterium protein" ; rdfs:subClassOf obo:VO_0010751 . obo:VO_0010754 obo:IAO_0000115 "a protein from a virus" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "virus protein" ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0010755 obo:IAO_0000115 "a protein from a parasite" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "parasite protein" ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0010756 obo:IAO_0000115 "a protein from fungus" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "fungus protein" ; rdfs:subClassOf obo:PR_000000001 . obo:VO_0010757 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Bacillus anthracis protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0010758 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Brucella protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010759 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Yersinia pestis protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010760 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Francisella tularensis protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010761 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Ebola virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010762 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Clostridium botulinum protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0010763 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Lassa Fever Virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010764 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Variola virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010765 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Campylobacter jejuni protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010766 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Escherichia coli protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010767 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Human Immunodeficiency Virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010768 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Hantavirus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010769 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Marburg Virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010770 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Mycobacterium tuberculosis protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0010771 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium spp. protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010772 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Haemophilus influenzae protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010773 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Coxiella burnetii protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010774 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "VEE Virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010775 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Clostridium tetani protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0010776 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Salmonella spp. protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010777 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Shigella protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010778 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neisseria meningitidis protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010779 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Streptococcus pneumoniae protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0010780 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Hepatitis A virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010781 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Hepatitis B virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010782 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Influenza virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010783 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Japanese encephalitis virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010784 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Measles virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010785 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Mumps virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010786 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Human papillomavirus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010787 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Poliovirus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010788 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Rabies virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010789 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Rotavirus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010790 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Rubella virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010791 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Yellow fever virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010792 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Varicella-zoster virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010793 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Tick-borne Encephalitis Virus (TBEV) protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010794 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Chlamydophila pneumoniae protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010795 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Chlamydia muridarum protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010796 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Yersinia pseudotuberculosis protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010797 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Bovine Leukemia virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010798 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Corynebacterium diphtheriae protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0010799 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Porcine circovirus 2 protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010800 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Pseudorabies virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010801 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Classical swine fever virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010802 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010803 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "West Nile virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010804 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Marek's disease virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010805 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Newcastle disease virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010806 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Feline leukemia virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010807 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Canine parvovirus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010808 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Canine coronavirus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010809 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Canine distemper virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010810 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Infectious Hematopoietic Necrosis Virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010811 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Lawsonia intracellularis protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010812 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Porphyromonas gulae protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010813 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Yersinia ruckeri protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010814 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Aeromonas salmonicida protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010815 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Vibrio anguillarum (Listonella anguillarum) protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010816 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Streptococcus equi protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0010817 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Chlamydophila abortus protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010818 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Mycoplasma synoviae protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010819 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Mycoplasma gallisepticum protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010820 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Bordetella avium protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010821 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Actinobacillus pleuropneumoniae protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010822 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Eimeria spp. protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010823 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Eimeria tenella protein" ; rdfs:subClassOf obo:VO_0010822 . obo:VO_0010824 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Theileria parva protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010825 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Theileria annulata protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010826 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Toxoplasma gondii protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010827 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Babesia bovis protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010828 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Neospora caninum protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010829 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Giardia duodenalis protein" ; rdfs:subClassOf obo:VO_0005477 . obo:VO_0010830 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Sarcocystis neurona protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010831 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Babesia canis protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010832 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania donovani protein" ; rdfs:subClassOf obo:VO_0015478 . obo:VO_0010833 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Eimeria maxima protein" ; rdfs:subClassOf obo:VO_0010822 . obo:VO_0010834 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Herpes simplex virus type 1 and 2 protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010835 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania major protein" ; rdfs:subClassOf obo:VO_0015478 . obo:VO_0010836 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania infantum protein" ; rdfs:subClassOf obo:VO_0015478 . obo:VO_0010837 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania amazonensis protein" ; rdfs:subClassOf obo:VO_0015478 . obo:VO_0010838 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma cruzi protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010839 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Chlamydophila psittaci protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010840 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Burkholderia pseudomallei protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010841 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Western equine encephalomyelitis virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010842 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Cryptosporidium parvum protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010843 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Hendra virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010844 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Dengue Virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010845 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Nipah virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010846 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Rickettsia spp protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010847 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Bordetella pertussis protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010848 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Vibrio cholerae protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010849 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Rift Valley Fever virus protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010850 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "SARS-CoV protein" ; rdfs:subClassOf obo:VO_0010754 . obo:VO_0010851 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Yersinia enterocolitica protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010852 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Entamoeba histolytica protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010853 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Coccidioides spp. protein" ; rdfs:subClassOf obo:VO_0010756 . obo:VO_0010854 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Trypanosoma brucei protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0010855 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Helicobacter pylori protein" ; rdfs:subClassOf obo:VO_0010753 . obo:VO_0010856 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """IMMUNOGENICITY: Induces antigen-specific Th1 immune response, as indicated by the specific induction of serum IgG2a, but not IgG1, antibodies and by the secretion of IFN-alpha but not IL-4, by the Cu/Zn SOD-stimulated splenocytes. Has been used for vaccine development [PubMed: 10816475][PubMed: 11953393][PubMed: 12933826]. MUTATION: An isogenic sodC mutant constructed from B abortus 2308 by gene replacement exhibited much greater susceptibility to killing by exogenous O(2)(-) than the parental 2308 strain, supporting a role for SodC in protecting this bacterium from O(2)(-) stress. The B abortus sodC mutant was much more sensitive to killing by cultured resident peritoneal macrophages from C57BL6J mice than 2308, and its attenuation in cultured murine macrophages was enhanced when these phagocytes were treated with gamma interferon. The attenuation of the B abortus sodC mutant in both resting and IFN-gamma-activated macrophages was alleviated in the presence of the NADPH oxidase inhibitor apocynin. Consistently, the B abortus sodC mutant also displayed significant attenuation in infected C57BL6J mice compared to the parental strain. These findings suggest that SodC protects B abortus 2308 from the respiratory burst of host macrophages [PubMed: 15845493].""" ; rdfs:label "SodC from B. abortus strain 2308" ; rdfs:seeAlso "VIOLILN Protegen ID: 3; NCBI Protein GI: 83269434; NCBI Protein Accession: YP_418725.1; NCBITaxon: 234" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010857 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Lef from B. anthracis str. A2012" ; rdfs:seeAlso "Protegen ID: 5; NCBI Gene GI: 1158731; NCBI Protein GI: 40646957; NCBI Protein Accession: AAR88323.1; NCBITaxon: 32630" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010757, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010858 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "EBOV GP" ; rdfs:seeAlso "Protegen ID: 10; NCBI Gene GI: 955190" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010859 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "EBOV NP" ; rdfs:seeAlso "Protegen ID: 11; NCBI Gene GI: 955194; NCBI Protein GI: 22789223; NCBI Protein Accession: NP_690580; NCBITaxon: 186539" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010860 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "VP24 from Reston ebolavirus" ; rdfs:seeAlso "Protegen ID: 12; NCBI Gene GI: 955193; NCBI Protein GI: 22789228; NCBI Protein Accession: NP_690586; NCBITaxon: 186539" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010861 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "VP40 from Reston ebolavirus" ; rdfs:seeAlso "Protegen ID: 13; NCBI Gene GI: 955192; NCBI Protein GI: 22789225; NCBI Protein Accession: NP_690582; NCBITaxon: 186539" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010862 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "VP30 from Reston ebolavirus" ; rdfs:seeAlso "Protegen ID: 14; NCBI Gene GI: 955196; NCBI Protein GI: 22789227; NCBI Protein Accession: NP_690585; NCBITaxon: 186539" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010863 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "VP35 from Reston ebolavirus" ; rdfs:seeAlso "Protegen ID: 15; NCBI Gene GI: 955189; NCBI Protein GI: 22789224; NCBI Protein Accession: NP_690581; NCBITaxon: 186539" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010864 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "VP35 expressed from alphavirus replicons induced a protective immune response in C57BL/6 mice when challenged with Ebola virus Zaire [PubMed: 11485406]." ; rdfs:label "VP35 from Zaire ebolavirus" ; rdfs:seeAlso "Protegen ID: 16; NCBI Gene GI: 911827; NCBI Protein GI: 10313992; NCBI Protein Accession: NP_066244; NCBITaxon: 186538" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010865 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant Tbp1 and Tbp2 proteins were expressed from Escherichia coli and antisera were raised to the purified proteins. In a passive model of bacteraemia, infant rats were protected from challenge with Hib after transfer of anti-rTbp2 antiserum, but not after anti-rTbp1 antiserum [PubMed: 8830248]." ; rdfs:label "Tbp2" ; rdfs:seeAlso "Protegen ID: 277; NCBI Gene GI: 3430457; NCBI Protein GI: 68249580; NCBI Protein Accession: YP_248692; NCBITaxon: 281310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010866 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "VP24 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406]." ; rdfs:label "VP24 from Zaire ebolavirus" ; rdfs:seeAlso "Protegen ID: 17; NCBI Gene GI: 911828; NCBI Protein GI: 10313998; NCBI Protein Accession: NP_066250; NCBITaxon: 186538" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010867 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "VP30 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406]." ; rdfs:label "VP30 from Zaire ebolavirus" ; rdfs:seeAlso "Protegen ID: 18; NCBI Gene GI: 911826; NCBI Protein GI: 10313997; NCBI Protein Accession: NP_066249; NCBITaxon: 186538" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010868 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """Vaccination of BALB/c or C57BL/6 mice with eVLPs, composed of the EBOV glycoprotein and matrix viral protein (VP)40 with a lipid membrane, in conjunction with QS-21 adjuvant resulted in mixed IgG subclass responses, a Th1-like memory cytokine response, and protection from lethal EBOV challenge [PubMed: 16002721]. VP40 expressed from alphavirus replicons induced a protective immune response in BALB/c mice when challenged with Ebola virus Zaire [PubMed: 11485406].""" ; rdfs:label "VP40 from Zaire ebolavirus" ; rdfs:seeAlso "Protegen ID: 19; NCBI Gene GI: 911825; NCBI Protein GI: 10313993; NCBI Protein Accession: NP_066245; NCBITaxon: 186538" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010869 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "HLA-A*0201 mice immunized with either GPC(42-50) from LASVsSgp2 glycoprotein or GPC(60-68) were protected against challenge with a recombinant vaccinia virus that expressed LASV GPC [PubMed: 16912286]." ; rdfs:label "LASVsSgp2 glycoprotein" ; rdfs:seeAlso "Protegen ID: 20; NCBI Gene GI: 956585; NCBI Protein GI: 23343511; NCBI Protein Accession: NP_694870; NCBITaxon: 11620" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010763, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010870 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Caf1 from Y. pestis biovar Microtus str. 91001" ; rdfs:seeAlso "Protegen ID: 23; NCBI Gene GI: 2767670; NCBI Protein GI: 45478667; NCBI Protein Accession: NP_995523; NCBITaxon: 229193" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010871 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "It has previously been shown that a DNA subunit vaccine (4pox) based on four orthopoxvirus immunogens (L1R, B5R, A27L and A33R) can produce protective immunity against lethal orthopoxvirus challenges in mice and nonhuman primates. the immunogenicity of an L1R construct to which a tissue plasminogen activator signal sequence was placed in frame with the full-length L1R gene was tested. When the tPA-L1R construct was substituted for the unmodified L1R gene in the 4pox vaccine, given as a prime and single boost, animals were better protected from lethal challenge with vaccinia virus (VACV) [PubMed: 18485547]." ; rdfs:label "L1R from Monkeypox virus Zaire-96-I-16" ; rdfs:seeAlso "Protegen ID: 28; NCBI Gene GI: 928938; NCBI Protein GI: 17974998; NCBI Protein Accession: NP_536512; NCBITaxon: 619591" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010764, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010872 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "PagA from B. anthracis str. Ames Ancestor" ; rdfs:seeAlso "Protegen ID: 32; NCBI Gene GI: 2820165; NCBI Protein GI: 47566476; NCBI Protein Accession: NC_007322.2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010757, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010873 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Lef from B. anthracis str. Ames Ancestor" ; rdfs:seeAlso "Protegen ID: 38; NCBI Gene GI: 2820148; NCBI Protein GI: 47566484; NCBI Protein Accession: NC_007322.2" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010757, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010874 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "MAb BA5 protected animals against plague, neutralized the Y. pestis type III secretion pathway and promoted opsonophagocytic clearance of bacteria in blood. LcrV residues 196-225 were necessary and sufficient for MAb BA5 binding. These results identify LcrV residues 196-225 as a linear epitope that is recognized by the murine immune system to confer plague protection [PubMed: 20005318]." ; rdfs:label "LcrV from y. pestis CO92" ; rdfs:seeAlso "Protegen ID: 44; NCBI Gene GI: 1172676; NCBI Protein GI: 16082719; NCBI Protein Accession: NP_395165; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010875 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "An LcrV variant lacking amino acid residues 271 to 300 (rV10) elicited immune responses that protected mice against a lethal challenge with Y. pestis [PubMed: 16041032]." ; rdfs:label "LcrV from Y. pestis KIM 10" ; rdfs:seeAlso "Protegen ID: 45; NCBI Gene GI: 1149310; NCBI Protein GI: 31795491; NCBI Protein Accession: NP_857946; NCBITaxon: 187410" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010876 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "V antigen" ; rdfs:seeAlso "Protegen ID: 46; NCBI Gene GI: 4118094" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010877 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study evaluated the humoral immune response of mice that survived lethal Y. pestis aerosol challenge after antibiotic treatment. Results indicated that one of the predominant antibody response of mice surviving pneumonic plague after treatment with antibiotics was to pla [PubMed: 10085037]." ; rdfs:label "Pla" ; rdfs:seeAlso "Protegen ID: 48; NCBI Gene GI: 1172643; NCBI Protein GI: 16082686; NCBI Protein Accession: NP_395233; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010878 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The type III secretion apparatus encoded on the low-calcium response (LCR) virulence plasmid, pCD1 in strain KIM5, of Y. pestis is a conserved virulence mechanism that is absolutely required for virulence of Y. pestis. YscF is a surface localized protein required both to secrete Yops and to translocate toxins into eukaryotic cells. YscF polymerization is possibly required for a YscF needle to puncture eukaryotic cell membranes. It is also likely that YscF and its homologs function to provide a base that a translocon complex is built upon, or that YscF builds a conduit from the bacterium to the eukaryotic membrane - this suggestion seems more likely given that other proteins such as YopB, YopD, and LcrV are also required for translocation into eukaryotic cells. YscF is thought to be a surface-expressed protein in Y. pestis and is required for virulence. YscF has been found to function as a protective antigen against experimental plague infection [PubMed: 15978133]." ; rdfs:label "YopD from Y. pestis CO92" ; rdfs:seeAlso "Protegen ID: 49; NCBI Gene GI: 1172673; NCBI Protein GI: 16082716; NCBI Protein Accession: NP_395162; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010879 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #3, gatA) was found to be protective. Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648]. Note: Part of CP #3 also belongs to gatB""" ; rdfs:label "GatA" ; rdfs:seeAlso "Protegen ID: 422; NCBI Protein GI: 62184918; NCBITaxon: 218497" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010880 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #3, gatB) was found to be protective. Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648]. Note: Part of CP #3 also belongs to gatA""" ; rdfs:label "GatB" ; rdfs:seeAlso "Protegen ID: 424; NCBI Protein GI: 62147986; NCBITaxon: 218497" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010881 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The MOMP (omp1) DNA immunization induced a non-specific and partial protection in OF1 outbred mice fetuses against challenge with C. abortus [PubMed: 12488563]." ; rdfs:label "Omp1" ; rdfs:seeAlso "Protegen ID: 425; NCBI Protein GI: 40601; NCBITaxon: 83555" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010882 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In pregnant mice, the dnaK vaccine induced a non-specific partial protection from abortion after challenge with Chlamydophila abortus [PubMed: 12056482]." ; rdfs:label "DnaK from Chlamydophila abortus" ; rdfs:seeAlso "Protegen ID: 426; NCBI Protein GI: 26006347; NCBITaxon: 83555" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010883 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The immunogenicity and protective effect of recombinant LcrE protein combined either with Freund's or Alum adjuvant were investigated in mice. The immunization with both protocols resulted in a significant reduction of the number of viable C. pneumoniae in the lungs after challenge. Results confirm that LcrE induces protective immunity in mice [PubMed: 19451031]." ; rdfs:label "LcrE" ; rdfs:seeAlso "Protegen ID: 428; NCBI Gene GI: 895078; NCBI Protein GI: 15618244; NCBI Protein Accession: NP_224529; NCBITaxon: 115713" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010794, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010884 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Results of this study showed that intranasal immunization of BALB/c mice with heat-aggregated CopN protein and an Escherichia coli heat-labile toxin (LT) induced a strong immune response. The immunization induced statistically significant protection against intranasal C. pneumoniae challenge, the level of which correlated with the magnitude of CopN-specific lymphocyte proliferation [PubMed: 16949182]." ; rdfs:label "CopN" ; rdfs:seeAlso "Protegen ID: 429; NCBI Protein GI: 33241669; NCBITaxon: 182082" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010794, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010885 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0512 showed significant levels of protection when compared to negative control animals. At 9 days following challenge TC0512 showed a 73% reduction in the number of recoverable Chlamydia compared with vector only immunized controls [PubMed: 17239501]." ; rdfs:label "TC0512 outer membrane protein, putative" ; rdfs:seeAlso "Protegen ID: 430; NCBI Gene GI: 1245872; NCBI Protein GI: 15835130; NCBI Protein Accession: NP_296889; NCBITaxon: 243161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010886 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0757 showed significant levels of protection when compared to negative control animals [PubMed: 17239501]." ; rdfs:label "TC0757 hypothetical protein" ; rdfs:seeAlso "Protegen ID: 431; NCBI Gene GI: 1246122; NCBI Protein GI: 15835371; NCBI Protein Accession: NP_297130; NCBITaxon: 243161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010887 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0439 showed significant levels of protection when compared to negative control animals [PubMed: 17239501]." ; rdfs:label "TC0439 adherence factor" ; rdfs:seeAlso "Protegen ID: 432; NCBI Gene GI: 1245792; NCBI Protein GI: 15835057; NCBI Protein Accession: NP_296816; NCBITaxon: 243161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010888 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0767/768 showed significant levels of protection when compared to negative control animals [PubMed: 17239501]." ; rdfs:label "TC0767 hypothetical protein" ; rdfs:seeAlso "Protegen ID: 433; NCBI Gene GI: 1246132; NCBI Protein GI: 15835381; NCBI Protein Accession: NP_297140; NCBITaxon: 243161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010889 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0767/768 showed significant levels of protection when compared to negative control animals [PubMed: 17239501]." ; rdfs:label "TC0768 hypothetical protein" ; rdfs:seeAlso "Protegen ID: 434; NCBI Gene GI: 1246133; NCBI Protein GI: 15835382; NCBI Protein Accession: NP_297141; NCBITaxon: 243161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010890 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Female BALB/c mice were immunized with chlamydial major outer membrane protein (MOMP) mixed with cholera toxin and CpG oligodeoxynucleotide adjuvants by either the IN or TCI routes. Both intranasal and transcutaneous immunization protected mice against respiratory challenge with Chlamydia [PubMed: 16153755]." ; rdfs:label "MOMP" ; rdfs:seeAlso "Protegen ID: 435; NCBI Protein GI: 1518659; NCBITaxon: 83560" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010891 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection. Overall, vaccination with DCs transfected with PmpG-1(25-500) exhibited the greatest degree of protective immunity among the four Chlamydia Ags tested [PubMed: 19155509]." ; rdfs:label "PmpG-1" ; rdfs:seeAlso "Protegen ID: 436; NCBI Gene GI: 1246433; NCBI Protein GI: 15834883; NCBI Protein Accession: NP_296642; NCBITaxon: 243161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010892 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection. In addition, RplF was able to engender protective immunity against challenge with C. muridarum [PubMed: 19155509]." ; rdfs:label "RplF" ; rdfs:seeAlso "Protegen ID: 437; NCBI Gene GI: 1246168; NCBI Protein GI: 15835415; NCBI Protein Accession: NP_297174; NCBITaxon: 243161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010893 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated with DCs transfected with individual Chlamydia protein PmpG-1(25-500), RplF, or PmpE/F-2(25-575) exhibited significant resistance to challenge infection. In addition, pmpE/F-2 was able to engender protective immunity against challenge with C. muridarum [PubMed: 19155509]." ; rdfs:label "PmpE/F-2" ; rdfs:seeAlso "Protegen ID: 438; NCBI Gene GI: 1246432; NCBI Protein GI: 15834882; NCBI Protein Accession: NP_296641; NCBITaxon: 243161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010795, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010894 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "IM-ID vaccination with CPn0095 (pknD) generated a response that resulted in moderately, but significantly reduced total C. pneumoniae lung loads as compared to control mice vaccinated with a plasmid expressing a non-Chlamydia ORF (p0.019). This resulted in the ability of CPN0095 to mediate a moderate, but statistically significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129]." ; rdfs:label "PknD" ; rdfs:seeAlso "Protegen ID: 439; NCBI Gene GI: 895704; NCBI Protein GI: 161353778; NCBI Protein Accession: NP_224303; NCBITaxon: 115713" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010794, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010895 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "M-ID vaccination with fabD generated a response that resulted in moderately, but significantly reduced total C. pneumoniae lung loads as compared to control mice vaccinated with a plasmid expressing a non-Chlamydia ORF (p 0.019). This resulted in the ability of fabD to mediate a moderate, but statistically significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129]." ; rdfs:label "FabD" ; rdfs:seeAlso "Protegen ID: 440; NCBI Gene GI: 894994; NCBI Protein GI: 15618217; NCBI Protein Accession: NP_224502; NCBITaxon: 115713" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010794, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010896 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated with candidate gene ssb showed significant reduction of spleen chlamydial loads as compared to nave, non-protected control mice (p 0.048). This resulted in the ability of ssb to mediate a modest, but significant level of protection in an inbred A/J mouse respiratory challenge model [PubMed: 16434129]." ; rdfs:label "Ssb" ; rdfs:seeAlso "Protegen ID: 441; NCBI Gene GI: 894901; NCBI Protein GI: 15618301; NCBI Protein Accession: NP_224586; NCBITaxon: 115713" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010794, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010897 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """Pigs were subjected to challenge infection with a dose of 1x10(5)TCID(50) (50% tissue culture infective dose) virulent CSFV strain. At 1 week post challenge infection, all of the yE2-immunized pigs were alive and without symptoms or signs of CSF. The yeast-expressed E2 protein retains correct immunogenicity and is able to induce a protective immune response against CSFV infection [PubMed: 19625145]. In a seperate study, swine vaccinated with VVR expressing E0 and/or E2 resisted a lethal challenge infection with CSFV. Glycoprotein E0 represents a second determinant for the induction of protective immunity against classical swine fever [PubMed: 7666549].""" ; rdfs:label "E2 from Classical swine fever virus" ; rdfs:seeAlso "Protegen ID: 442; NCBI Gene GI: 920146; NCBI Protein GI: 12657942; NCBI Protein Accession: NP_075354; NCBITaxon: 11096" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010801, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010898 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Swine vaccinated with VVR expressing E0 and/or E2 resisted a lethal challenge infection with CSFV. Glycoprotein E0 represents a second determinant for the induction of protective immunity against classical swine fever [PubMed: 7666549]." ; rdfs:label "E0" ; rdfs:seeAlso "Protegen ID: 443; NCBI Protein GI: 115343287; NCBITaxon: 11096" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010801, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010899 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intramuscular vaccination of pigs with immunoaffinity-purified E1 (gp55) in a double water-oil emulsion elicited high titers of neutralizing antibodies between 2 and 4 weeks after vaccination at the lowest dose tested (20 micrograms). The vaccinated pigs were completely protected against intranasal challenge with 100 50% lethal doses of HCV (Classical swine fever virus) strain Brescia [PubMed: 8350404]." ; rdfs:label "Gp55" ; rdfs:seeAlso "Protegen ID: 444; NCBI Protein GI: 1763691; NCBITaxon: 11096" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010801, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010900 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A single dose of ciBoNT/A1 HP provided equivalent or greater protective immunity, not only against the homologous toxin, but also against two distinct toxin subtypes with significant amino acid divergence in mice when challenged with BoNT/A subtypes /A1, /A2, and /A3 from Clostridium botulinum [PubMed: 19450643]." ; rdfs:label "BoNT/A1 from C. botulinum" ; rdfs:seeAlso "Protegen ID: 445; NCBI Protein GI: 241183337; NCBITaxon: 1491" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010762, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010901 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Purified FHc was used to vaccinate mice and evaluate their survival against challenge with active botulinum neurotoxin serotype F (BoNT/F). Mice that received one injection of 5 microg or two injections of >or=0.04 microg of FHc were completely protected [PubMed: 18845829]." ; rdfs:label "FHc" ; rdfs:seeAlso "Protegen ID: 446; NCBI Protein GI: 166236883; NCBITaxon: 32630" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010762, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010902 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A completely synthetic gene encoding fragment C, a approximately 50-kDa fragment, of botulinum neurotoxin serotype A was constructed from oligonucleotides. Mice given three subcutaneous vaccinations were protected against an intraperitoneal administration of 10^6 50% lethal doses (ID50) of serotype A toxin [PubMed: 7790092]." ; rdfs:label "BotA" ; rdfs:seeAlso "Protegen ID: 447; NCBI Protein GI: 733429; NCBITaxon: 32630" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010762, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010903 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice and rabbits were immunized with recombinant HCR/A1 (rHCR/A1) from the classical type A-Hall strain (ATCC 3502) (BoNT/A1) and rHCR/E from BoNT serotype E Beluga (BoNT/E(B)). The protection elicited by rHCR/A1 to BoNT/A1 and BoNT/A2 and by rHCR/E(B) to BoNT/E(A) indicate that immunization with receptor binding domains elicit protection within sub-serotypes of BoNT [PubMed: 16177380]." ; rdfs:label "BoNT/A1 from C. botulinum A str. Hall" ; rdfs:seeAlso "Protegen ID: 448; NCBI Gene GI: 5398487; NCBI Protein GI: 153936924; NCBI Protein Accession: YP_001386738; NCBITaxon: 441771" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010762, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010904 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The DNA replicon vaccine (pSCARSBHc) encoding the Hc domain of BoNT/B (BHc) induced better responses and protection against BoNT/B mouse challenge than conventional DNA vaccine. Recombinant SFV particle VRP-BHc protected mice from high-dose BoNT/B challenge [PubMed: 19712769]." ; rdfs:label "BoNT/B" ; rdfs:seeAlso "Protegen ID: 449; NCBI Gene GI: 6030102; NCBI Protein GI: 169834607; NCBI Protein Accession: YP_001693307; NCBITaxon: 498213" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010762, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010905 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers constructed a replication-incompetent adenovirus encoding a synthesized codon-optimized gene for expression of the heavy chain C-fragment (H(C)50) of botulinum neurotoxin type C (BoNT/C). After a single dose of 2 x 10^7pfu adenoviral vectors in a mouse model, the animals were completely protected against intraperitoneal challenge with 100 x MLD(50) of active BoNT/C [PubMed: 17897756]." ; rdfs:label "BoNT/C(Hc50)" ; rdfs:seeAlso "Protegen ID: 450; NCBI Protein GI: 217781; NCBI Protein Accession: BAA14235.1; NCBITaxon: 12336" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010762, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010906 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A recombinant vaccinia virus containing most of the P1 region of hepatitis A virus (HAV) was constructed bearing epitopes from structural polypeptides VP4, -3 and -2, and the N terminus of VP. Inoculation of tamarin monkeys with the recombinant virus resulted in the development of a specific anti-HAV immune response which was protective against challenge with a virulent strain of HAV [PubMed: 1654376]." ; rdfs:label "HAVgp2" ; rdfs:seeAlso "Protegen ID: 680; NCBI Gene GI: 1493919; NCBI Protein GI: 9626734; NCBI Protein Accession: NP_041008; NCBITaxon: 12092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010780, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010907 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following two intragastric immunizations in BALB/c mice, the Yersinia vectors harboring a DNA vaccine encoding BFR (P39) induced antigen-specific serum immunoglobulin and Th1-type responses among splenocytes. The best protection was conferred by a serotype O:9 strain carrying pCIP39, confirming the importance of the P39 T-cell antigen in this mechanism [PubMed: 11895955]." ; rdfs:label "Bfr from B. abortus S19" ; rdfs:seeAlso "Protegen ID: 681; NCBI Gene GI: 6326162; NCBI Protein GI: 189022832; NCBI Protein Accession: YP_001932573; NCBITaxon: 430066" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010908 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study was designed to evaluate the immunogenicity and the protective efficacy of a divalent fusion DNA vaccine encoding both the Brucella abortus L7/L12 protein (ribosomal protein, rplL) and Omp16 protein (outer membrane lipoprotein). This divalent DNA vaccine induced a significant level of protection against challenge with the virulent B. abortus in BALB/c mice [PubMed: 16622210]." ; rdfs:label "RplL" ; rdfs:seeAlso "Protegen ID: 682; NCBI Gene GI: 3788918; NCBI Protein GI: 82700077; NCBI Protein Accession: YP_414651; NCBITaxon: 359391" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010909 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The fragment C of tetanus toxin was amplified from Clostridium tetani DNA by PCR. Immunization of mice with rTTC resulted in the production of antibodies that were able to protect mice against a challenge with tetanus toxin furthermore, rTTC in vivo appeared to be able to undergo retrograde axonal transport [PubMed: 12075415]." ; rdfs:label "TTC" ; rdfs:seeAlso "Protegen ID: 451; NCBI Protein GI: 157829735; NCBITaxon: 1513" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010775, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010910 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Cynomolgus macaques were immunized with DNA/rAd5 vaccines expressing ZEBOV (GP) and SEBOV glycoprotein (GP) prior to lethal challenge with BEBOV. Vaccinated subjects developed robust, antigen-specific humoral and cellular immune responses against the GP from ZEBOV as well as cellular immunity against BEBOV GP, and immunized macaques were uniformly protected against lethal challenge with BEBOV [PubMed: 20502688]." ; rdfs:label "GP from Zaire ebolavirus" ; rdfs:seeAlso "Protegen ID: 452; NCBI Gene GI: 911829; NCBI Protein GI: 10313995; NCBI Protein Accession: NP_066246; NCBITaxon: 186538" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010911 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Cynomolgus macaques were immunized with DNA/rAd5 vaccines expressing ZEBOV (GP) and SEBOV glycoprotein (GP) prior to lethal challenge with BEBOV. Vaccinated subjects developed robust, antigen-specific humoral and cellular immune responses against the GP from ZEBOV as well as cellular immunity against BEBOV GP, and immunized macaques were uniformly protected against lethal challenge with BEBOV [PubMed: 20502688]." ; rdfs:label "GP from Sudan ebolavirus" ; rdfs:seeAlso "Protegen ID: 453; NCBI Gene GI: 3160774; NCBI Protein GI: 55770812; NCBI Protein Accession: YP_138523; NCBITaxon: 186540" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010912 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Guinea pigs infected with a single intranasal inoculation of HPIV3/EboGP-NP showed no apparent signs of disease yet developed a strong humoral response specific to the EV proteins. When these animals were challenged with an intraperitoneal injection of 10(3) PFU of EV, there were no outward signs of disease, no viremia or detectable EV antigen in the blood, and no evidence of infection in the spleen, liver, and lungs. In contrast, all of the control animals died or developed severe EV disease following challenge [PubMed: 16474134]." ; rdfs:label "NP" ; rdfs:seeAlso "Protegen ID: 454; NCBI Gene GI: 911830; NCBI Protein GI: 10314000; NCBI Protein Accession: NP_066243; NCBITaxon: 186538" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010761, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010913 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Ten mice were inoculated subcutaneously, administered booster injections after one month, and challenged with 130 LD(50) of wild type Y. pestis CO92. The vaccinated animals produced high levels of specific antibodies against YscF as determined by Western blot. The data were statistically significant (P = 0.053 by two-tailed Fisher's test), suggesting that the YscF protein can provide a protective immune response against lethal plague challenge during subcutaneous plague infection [PubMed: 15939303]." ; rdfs:label "YscF from Y. pestis CO92" ; rdfs:seeAlso "Protegen ID: 54; NCBI Gene GI: 1172700; NCBI Protein GI: 16082743; NCBI Protein Accession: NP_395189; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010914 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The P4 protein is an integral outer membrane protein that has a role in acquiring hemin and nucleosides [PubMed: 1715322 ]." ; rdfs:label "P4 from Haemophilus influenzae" ; rdfs:seeAlso "Protegen ID: 100; NCBITaxon: 727" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010915 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant P6 (pal) was capable of eliciting a protective antibody response against live H. influenzae type b challenge in a modified infant rat model of bacteremia [PubMed: 9261944]." ; rdfs:label "Pal" ; rdfs:seeAlso "Protegen ID: 101; NCBI Gene GI: 3429820; NCBI Protein GI: 68248984; NCBI Protein Accession: YP_248096; NCBITaxon: 281310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010916 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "When mice immunized intranasally with recombinant protein corresponding to the C-terminal region of Hap(S) from H. influenzae strains N187, P860295, and TN106 plus mutant cholera toxin CT-E29H were challenged with strain TN106, they were protected against nasopharyngeal colonization [PubMed: 15557618]." ; rdfs:label "Hap from H. influenzae" ; rdfs:seeAlso "Protegen ID: 103; Protegen ID: 102; NCBI Protein GI: 21686508; NCBITaxon: 727" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010917 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0010916 ; a owl:Class ; rdfs:label "obsolete Hap from H. influenzae" ; rdfs:seeAlso "Protegen ID: 103; NCBITaxon: 727" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0010918 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "OMP26 was used to immunize rats via intestinal Peyer's patches, followed by an intratracheal boost. Immunization was found to significantly enhance bacterial clearance following pulmonary challenge with both the homologous NTHI strain and a different NTHI strain [PubMed: 9573117]." ; rdfs:label "Omp26" ; rdfs:seeAlso "Protegen ID: 276; NCBI Nucleotide GI: 4574245; NCBI Protein GI: 4574246; NCBI Protein Accession: AAD23967.1; NCBITaxon: 727" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010919 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The heterologous prime-boost strategy of live Salmonella vaccine expressing Mycobacterium tuberculosis fusion antigen Age5B-ESAT6 (esxA) from the chromosome followed by a systemic boost of antigen and adjuvant reduced the levels of M. tuberculosis bacteria in the lungs and spleen to the same extent as BCG. Additionally, this vaccination regimen was observed to be statistically equivalent in terms of protection to immunisation with BCG [PubMed: 19755145]." ; rdfs:label "EsxA" ; rdfs:seeAlso "Protegen ID: 104; NCBI Gene GI: 886209; NCBI Protein GI: 57117165; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010920 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "TRAP from P. falciparum" ; rdfs:seeAlso "Protegen ID: 138; NCBI Gene GI: 814170; NCBI Protein GI: 124513464; NCBI Protein Accession: XP_001350088; NCBITaxon: 36329" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010921 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "LolC was evaluated as an antigen for a vaccine candidate against B. pseudomallei infection. Nonmembrane regions of the B. pseudomallei protein was expressed and purified from Escherichia coli and then evaluated as a vaccine candidate in an established mouse model of B. pseudomallei infection. When delivered with the monophosphoryl lipid A-trehalose dicorynomycolate adjuvant, the protein stimulated antigen-specific humoral and cellular immune responses. Immunization with the LolC protein domain afforded significant protection against a subsequent challenge with B. pseudomallei. LolC provided a greater level of protection when it was administered with immune-stimulating complexes complexed with CpG oligodeoxynucleotide 10103. Immunization with LolC also protected against a subsequent challenge with a heterologous strain of B. pseudomallei, demonstrating the potential utility of this protein as a vaccine antigen for melioidosis [PubMed: 17517877]." ; rdfs:label "LolC/E" ; rdfs:seeAlso "Protegen ID: 768; NCBI Gene GI: 3093214; NCBI Protein GI: 53719887; NCBI Protein Accession: YP_108873; NCBITaxon: 272560" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010840, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010922 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "PotF was evaluated as an antigen for a vaccine candidate against B. pseudomallei infection. Nonmembrane regions of the B. pseudomallei protein was expressed and purified from Escherichia coli and then evaluated as a vaccine candidate in an established mouse model of B. pseudomallei infection. When delivered with the monophosphoryl lipid A-trehalose dicorynomycolate adjuvant, the protein stimulated antigen-specific humoral and cellular immune responses. Immunization with the PotF protein domain afforded significant protection against a subsequent challenge with B. pseudomallei [PubMed: 17517877]." ; rdfs:label "PotF" ; rdfs:seeAlso "Protegen ID: 769; NCBI Gene GI: 3095748; NCBI Protein GI: 53721504; NCBI Protein Accession: YP_110489; NCBITaxon: 272560" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010840, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010923 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "AMA1 from P. falciparum 3D7" ; rdfs:seeAlso "Protegen ID: 139; NCBI Gene GI: 810891; NCBI Protein GI: 124804478; NCBI Protein Accession: XP_001348015; NCBITaxon: 36329" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000137 ] . obo:VO_0010924 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The ompA codon was adapted to the codon usage in birds, resulting in pcDNA1/MOMP(opt). Researchers examined the capacity of nebulised or intramuscularly (IM) administered brPEI-pcDNA1/MOMP(opt) to induce a significant protective immune response in SPF turkeys experimentally infected with 10^8 TCID(50) of a virulent Cp. psittaci strain. Vaccinated groups were significantly protected against Cp. psittaci challenge [PubMed: 20199760]." ; rdfs:label "OmpA from C. psittaci" ; rdfs:seeAlso "Protegen ID: 766; NCBI Protein GI: 94467392; NCBITaxon: 83554" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010839, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010925 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Plasmid DNA (pcDNA1::MOMP A) expressing the major outer membrane protein (MOMP) of Chlamydophila psittaci genotype A strain 89/1051 has been tested for its ability to induce protective immunity against Cp. psittaci challenge in budgerigars. DNA immunisation significantly reduced clinical signs, macroscopic lesions, pharyngeal and cloacal excretion as well as chlamydial replication, even in the presence of pre-existing serum antibodies, as compared to the placebo-vaccinated controls [PubMed: 19640395]." ; rdfs:label "MOMP from C. psittaci" ; rdfs:seeAlso "Protegen ID: 767; NCBI Nucleotide GI: 144544; NCBI Protein GI: 144545; NCBI Protein Accession: AAA17396.1; NCBITaxon: 83554" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010839, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010926 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 11489167]" ; rdfs:label "ABRA" ; rdfs:seeAlso "Protegen ID: 137; NCBITaxon: 5835" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010771, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:OPL_0000270 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010927 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "This gene was originally isolated from a lambda gt11 expression library probed with sera from Brucella-infected sheep. Sequence analysis of the cloned gene revealed the presence of an open reading frame of 158 amino acids encoding a protein of 17.3 kDa [PubMed: 7664168 ]. It was later identified as a cytoplasmic protein lumazine synthase [PubMed: 10482294 ]. This gene can be used for diagnosis [PubMed: 7664168 ] [PubMed: 10482294 ] and vaccine development [PubMed: 11953389 ]." ; rdfs:label "ORF" ; rdfs:seeAlso "Protegen ID: 113; NCBI Nucleotide GI: 599653; NCBI Protein GI: 599654; NCBI Protein Accession: CAA86936.1; NCBITaxon: 235" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010928 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "B. abortus strain 19 L7/L12" ; rdfs:seeAlso "Protegen ID: 114; NCBI Protein GI: 304271" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010929 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Guinea pigs were vaccinated with recombinant VEE replicons (packaged into VEE-like particles), inoculated with MBGV, and evaluated for viremia and survival after challenge with typical MGBV disease. Results indicated that VP35 afforded incomplete protection [PubMed: 9813200 ]." ; rdfs:label "VP35 from Marburg Virus" ; rdfs:seeAlso "Protegen ID: 167; NCBI Gene GI: 920948; NCBI Protein GI: 13489277; NCBI Protein Accession: NP_042026.1; NCBITaxon: 11269" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010769, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010930 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The purified recombinant proteins, P1, HspB, and P1-HspB, and whole-cell antigen (WCA) of C. burnetii were used to immunize BALB/c mice. Protective immunity against Q fever was induced with a recombinant P1 antigen fused with HspB after Coxiella burnetii challenge [PubMed: 16481504 ]." ; rdfs:label "P1 from Coxiella burnetii" ; rdfs:seeAlso "Protegen ID: 171; NCBI Protein GI: 30025845; NCBITaxon: 777" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010773, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010931 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "NP from Zaire ebolavirus" ; rdfs:seeAlso "Protegen ID: 172; NCBI Gene GI: 911830; NCBI Protein GI: 10314000; NCBI Protein Accession: NP_066243; NCBITaxon: 186538" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010769, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010932 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "GP from Marburg Virus" ; rdfs:seeAlso "Protegen ID: 173; NCBI Protein GI: 21702651; NCBITaxon: 186538" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010769, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010933 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "NP Marburgvirus - Ravn" ; rdfs:seeAlso "Protegen ID: 174; NCBI Protein GI: 91177744; NCBITaxon: 378809" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010769, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010934 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The purified recombinant proteins, P1, HspB, and P1-HspB, and whole-cell antigen (WCA) of C. burnetii were used to immunize BALB/c mice. Protective immunity against Q fever was induced with a recombinant P1 antigen fused with HspB after Coxiella burnetii challenge [PubMed: 16481504 ]." ; rdfs:label "HspB from Coxiella burnetii" ; rdfs:seeAlso "Protegen ID: 175; NCBI Protein GI: 197253489; NCBITaxon: 777" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010773, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010935 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice were immunized with recombinant H3L protein to examine H3L-specific antibody responses in greater detail. H3L-immunized mice developed high-titer vaccinia virus-neutralizing antibodies (mean PRNT50 = 1:3,760). Importantly, H3L-immunized mice were subsequently protected against lethal intranasal challenges with 1 or 5 50% lethal doses (LD50) of pathogenic vaccinia virus strain WR, demonstrating the in vivo value of an anti-H3L response. To formally demonstrate that neutralizing anti-H3L antibodies are protective in vivo, we performed anti-H3L serum passive-transfer experiments. Mice receiving H3L-neutralizing antiserum were protected from a lethal challenge with 3 LD50 of vaccinia virus strain WR (5/10 versus 0/10; P < 0.02) [PubMed: 16140750]." ; rdfs:label "H3L" ; rdfs:seeAlso "Protegen ID: 62; NCBI Gene GI: 3707557; NCBI Protein GI: 66275898; NCBI Protein Accession: YP_232983; NCBITaxon: 10245" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010764, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010936 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Ag85A" ; rdfs:seeAlso "Protegen ID: 154; NCBITaxon: 1773" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010937 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Env Gp160" ; rdfs:seeAlso "Protegen ID: 153; NCBITaxon: 11676" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010767, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010938 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "StxB2" ; rdfs:seeAlso "Protegen ID: 225; NCBI Gene GI: 1262010; NCBI Protein GI: 9632507; NCBI Protein Accession: NP_049501; NCBITaxon: 10730" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010939 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Omp31" ; rdfs:seeAlso "Protegen ID: 231; NCBI Gene GI: 3788834; NCBI Protein GI: 82700421; NCBI Protein Accession: YP_414995; NCBITaxon: 359391" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010940 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Tir" ; rdfs:seeAlso "Protegen ID: 199; NCBI Gene GI: 960860; NCBI Protein GI: 15804222; NCBI Protein Accession: NP_290261.1; NCBITaxon: 562" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010941 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "ETEC also expresses a range of colonisation factor antigens (CFAs), which allow adherence to the mucosal surface and therefore colonisation of the intestine. Some CFAs are sub-divided into coli surface (CS) antigens [PubMed: 17566016]." ; rdfs:label "CS1" ; rdfs:seeAlso "Protegen ID: 79; NCBI Gene GI: 4188469; NCBI Protein GI: 110643341; NCBI Protein Accession: YP_671071; NCBITaxon: 362663" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010942 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "FlaA from C. jejuni NCTC 11168" ; rdfs:seeAlso "Protegen ID: 87; NCBI Gene GI: 905631; NCBI Protein GI: 15792662; NCBI Protein Accession: NP_282485.1; NCBITaxon: 197" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010943 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "LT is a hetero-oligomeric AB5 type enterotoxin composed of a 27 kDa A subunit with toxic ADP ribosyl transferase activity and a stable noncovalent-linked pentamer of 11.6 kDa B subunits. ETEC infection and colonization of the small intestine, and the production of LT, causes acute diarrhea that can be fatal without intervention [PubMed: 17188785]." ; rdfs:label "EltB" ; rdfs:seeAlso "Protegen ID: 92; NCBI Protein GI: 157021162; NCBITaxon: 562" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010944 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "EHEC strains produce intimin, an outer membrane adhesin encoded by the eae gene located in a chromosomal pathogenicity island termed the locus of enterocyte effacement [PubMed: 17258324]." ; rdfs:label "Eae" ; rdfs:seeAlso "Protegen ID: 93; NCBI Gene GI: 960862; NCBI Protein GI: 15804220; NCBI Protein Accession: NP_290259; NCBITaxon: 155864" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010945 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "FimH is a protective antigen [PubMed: 9110982]" ; rdfs:label "FimH from E. coli UTI89" ; rdfs:seeAlso "Protegen ID: 263; NCBI Gene GI: 3992235; NCBI Protein GI: 91213965; NCBI Protein Accession: YP_543951; NCBITaxon: 364106" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010946 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 10710308]." ; rdfs:label "GNA2132" ; rdfs:seeAlso "Protegen ID: 264; NCBI Gene GI: 903357; NCBI Protein GI: 15677945; NCBI Protein Accession: NP_275117; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010947 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 10710308]" ; rdfs:label "GNA2001" ; rdfs:seeAlso "Protegen ID: 265; NCBI Gene GI: 904124; NCBI Protein GI: 15677829; NCBI Protein Accession: NP_274993; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010948 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The 39-kDa protein is immunogenic." ; rdfs:label "B. melitensis M5 P39" ; rdfs:seeAlso "Protegen ID: 110; NCBI Protein GI: 122892474; NCBI Protein Accession: ABM67295" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010949 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A novel primate lentivirus was identified in Mandrillus sphinx. One of the newly isolated SIV strains was intravenously inoculated into two rhesus macaques and resulted in chronic infection. These SIVs do not cluster with SIVmndGB1, the former representative strain of SIVmnd, but form a new, independent lineage. These results indicate that these SIVmnds are a novel type of SIVmnd and have infected Cameroonian mandrills for a long time. To date, M. sphinx is the only primate species other than humans that is naturally infected with two different types of SIV [PubMed: 11522184]." ; rdfs:label "Gag protein from SIV-mnd 2" ; rdfs:seeAlso "Protegen ID: 98; NCBI Gene GI: 956108; NCBITaxon: 159122" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010767, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010950 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination of mice and guinea pigs with a secA2 mutant significantly increased resistance to M. tuberculosis challenge compared with standard M. bovis bacille Calmette-Gurin vaccination [PubMed: 17671656]." ; rdfs:label "SecA2" ; rdfs:seeAlso "Protegen ID: 117; NCBI Gene GI: 885594; NCBI Protein GI: 15608958; NCBI Protein Accession: NP_216337; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010951 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The 10-kDa culture filtrate protein (CFP-10, esxB) and 6-kDa early secretory antigen of T cells (ESAT-6) are secreted in abundance by Mycobacterium tuberculosis. Study demonstrated that protective immunity is induced by CFP-10 DNA vaccination in C3H mice as measured by a CFU reduction in the lung and spleen 4 and 8 weeks after challenge with M. tuberculosis [PubMed: 18332205]." ; rdfs:label "EsxB" ; rdfs:seeAlso "Protegen ID: 121; NCBI Gene GI: 886194; NCBI Protein GI: 15611010; NCBI Protein Accession: NP_218391; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010952 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers have developed DNA vaccines expressing M. tuberculosis antigen 85A (Ag85A, fbpA) and cytokine granulocyte macrophage colony stimulating factor (GM-CSF). The immune strategy of BCG-prime and DNA vaccine boost induced mice to generate efficient immune protection against M. tuberculosis challenge [PubMed: 19450898]." ; rdfs:label "FbpA" ; rdfs:seeAlso "Protegen ID: 122; NCBI Gene GI: 886132; NCBI Protein GI: 15610940; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010953 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "PepA" ; rdfs:seeAlso "Protegen ID: 123; NCBI Gene GI: 886924; NCBI Protein GI: 15607267; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010954 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "PPE18" ; rdfs:seeAlso "Protegen ID: 124; NCBI Gene GI: 886073; NCBI Protein GI: 57116841; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010955 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "CjaA from C. jejuni RM 1221" ; rdfs:seeAlso "Protegen ID: 133; NCBI Gene GI: 3231573; NCBI Protein GI: 57237809; NCBI Protein Accession: YP_179057.1; NCBITaxon: 197" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010956 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A total of 840 Light Sussex chickens were used to evaluate a Salmonella enterica serovar Typhimurium DeltaaroA vaccine expressing the C. jejuni amino acid binding protein CjaA. Chickens were given the vaccine at 1-day-old and two weeks later by oral gavage, then challenged after a further two weeks with C. jejuni. Across six biological replicates, statistically significant reductions in caecal C. jejuni of c. 1.4log(10) colony-forming units/g were observed at three and four weeks post-challenge relative to age-matched unvaccinated birds. Protection was associated with the induction of CjaA-specific serum IgY and biliary IgA [PubMed: 19853682]." ; rdfs:label "CjaA from C. jejuni" ; rdfs:seeAlso "Protegen ID: 134; NCBI Protein GI: 1813949; NCBITaxon: 197" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010957 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Pvs25" ; rdfs:seeAlso "Protegen ID: 141; NCBITaxon: 5855" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010958 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Aotus monkeys were challenged with the virulent Vietnam Oak Knoll (FVO) strain of P. falciparum. Vaccination of A. nancymai with yMSP1(19) induced protective immune responses. Both of the A. nancymai vaccinated with yMSP1(19) self-resolved an otherwise lethal infection [PubMed: 8529111]." ; rdfs:label "MSP1 from P. falciparum" ; rdfs:seeAlso "Protegen ID: 143; NCBI Protein GI: 94420988; NCBITaxon: 5833" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000130 ] . obo:VO_0010959 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "RESA" ; rdfs:seeAlso "Protegen ID: 144" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010771, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010960 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study compared the immunogenicity and protective efficacy of recombinant DOBV nucleocapsid protein (rDOBV N, S) given with Alum or Freund's as adjuvant, or PBS, in C57/BL6 mice. Mice receiving rDOBV N with Freund's adjuvant were protected from challenge (75% protected) [PubMed: 15364453]." ; rdfs:label "S nucleocapsid protein from Dobrava-Belgrade virus" ; rdfs:seeAlso "Protegen ID: 146; NCBI Gene GI: 2656266; NCBI Protein GI: 38505524; NCBI Protein Accession: NP_942553; NCBITaxon: 12506" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010961 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study developed replication-competent vaccines against EBOV and MARV based on attenuated recombinant vesicular stomatitis virus vectors expressing either the EBOV glycoprotein or MARV glycoprotein from Lake Victoria marburgvirus - Musoke. A single intramuscular injection of the EBOV or MARV vaccine elicited completely protective immune responses in nonhuman primates against lethal EBOV or MARV challenges [PubMed: 15937495]." ; rdfs:label "GP from Lake Victoria marburgvirus" ; rdfs:seeAlso "Protegen ID: 150; NCBI Protein GI: 77543430; NCBITaxon: 33727" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010769, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010962 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "This is a protective antigen [PubMed: 17239499]." ; rdfs:label "Bp26" ; rdfs:seeAlso "Protegen ID: 232; NCBI Gene GI: 1196247; NCBI Protein GI: 17986819; NCBI Protein Accession: NP_539453; NCBITaxon: 224914" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010963 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "RpsL" ; rdfs:seeAlso "Protegen ID: 236; NCBI Gene GI: 1196463; NCBI Protein GI: 161511151; NCBI Protein Accession: NP_539669; NCBITaxon: 224914" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010964 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Iss" ; rdfs:seeAlso "Protegen ID: 240; NCBI Gene GI: 5616654; NCBI Protein GI: 157418230; NCBI Protein Accession: YP_001481302; NCBITaxon: 405955" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010965 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "FyuA" ; rdfs:seeAlso "Protegen ID: 247; NCBI Gene GI: 4492541; NCBI Protein GI: 117624167; NCBI Protein Accession: YP_853080; NCBITaxon: 405955" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010966 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Brucella Omp25 is a protective antigen [PubMed: 17049676]." ; rdfs:label "Omp25" ; rdfs:seeAlso "Protegen ID: 253; NCBI Gene GI: 1196960; NCBI Protein GI: 17987532; NCBI Protein Accession: NP_540166; NCBITaxon: 224914" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010967 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Brucella IalB is a protective antigen [PubMed: 17049676]." ; rdfs:label "IalB" ; rdfs:seeAlso "Protegen ID: 254; NCBI Gene GI: 1197295; NCBI Protein GI: 17987867; NCBI Protein Accession: NP_540501; NCBITaxon: 224914" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010968 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Brucella bacterioferritin is a protective antigen [PubMed: 11447155 ]" ; rdfs:label "Bfr from B. melitensis biovar Abortus 2308" ; rdfs:seeAlso "Protegen ID: 255; NCBI Gene GI: 3828133; NCBI Protein GI: 83269559; NCBI Protein Accession: YP_418850; NCBITaxon: 359391" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010969 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "protective antigen [PubMed: 17239499]" ; rdfs:label "Tig" ; rdfs:seeAlso "Protegen ID: 256; NCBI Gene GI: 1196780; NCBI Protein GI: 17987352; NCBI Protein Accession: NP_539986; NCBITaxon: 224914" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010970 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Brucella DnaK is a protective antigen [PubMed: 17686554]." ; rdfs:label "DnaK from Brucella" ; rdfs:seeAlso "Protegen ID: 257; NCBI Gene GI: 3341115; NCBI Protein GI: 62290965; NCBI Protein Accession: YP_222758; NCBITaxon: 262698" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010971 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Brucella SurA is a protective antigen [PubMed: 17686554]." ; rdfs:label "SurA" ; rdfs:seeAlso "Protegen ID: 258; NCBI Gene GI: 3787419; NCBI Protein GI: 82699574; NCBI Protein Accession: YP_414148; NCBITaxon: 359391" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010972 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Brucella Omp19 is a protective antigen [PubMed: 18981242]." ; rdfs:label "Omp19" ; rdfs:seeAlso "Protegen ID: 259; NCBI Gene GI: 3788831; NCBI Protein GI: 82700695; NCBI Protein Accession: YP_415269; NCBITaxon: 359391" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010973 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Brucella Omp16 is a protective antigen [PubMed: 18981242]." ; rdfs:label "Omp16" ; rdfs:seeAlso "Protegen ID: 260; NCBI Gene GI: 3788229; NCBI Protein GI: 82700483; NCBI Protein Accession: YP_415057; NCBITaxon: 359391" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010974 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 10710308]" ; rdfs:label "GNA1946" ; rdfs:seeAlso "Protegen ID: 266; NCBI Gene GI: 904205; NCBI Protein GI: 15677776; NCBI Protein Accession: NP_274940; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010975 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 10710308]" ; rdfs:label "GNA1220" ; rdfs:seeAlso "Protegen ID: 267; NCBI Gene GI: 903642; NCBI Protein GI: 15677093; NCBI Protein Accession: NP_274245; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010976 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen[PubMed: 10710308]" ; rdfs:label "GNA1162" ; rdfs:seeAlso "Protegen ID: 268; NCBI Gene GI: 903582; NCBI Protein GI: 15677037; NCBI Protein Accession: NP_274189; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010977 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 10710308]" ; rdfs:label "GNA992 (hsf)" ; rdfs:seeAlso "Protegen ID: 269; NCBI Gene GI: 903112; NCBI Protein GI: 15676883; NCBI Protein Accession: NP_274028; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010978 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 10710308]" ; rdfs:label "GNA33" ; rdfs:seeAlso "Protegen ID: 270; NCBI Gene GI: 902136; NCBI Protein GI: 15675973; NCBI Protein Accession: NP_273099; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010979 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 9104804]" ; rdfs:label "NspA from N. meningitidis MC58" ; rdfs:seeAlso "Protegen ID: 271; NCBI Gene GI: 902774; NCBI Protein GI: 15676561; NCBI Protein Accession: NP_273705; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010980 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 16825336][PubMed: 12045242] with GeneID: 902509. However, according to sequence analysis, this nadA is not the same NadA that was found to be protective antigen [PubMed: 16825336][PubMed: 12045242]." ; rdfs:label "NadA" ; rdfs:seeAlso "Protegen ID: 272; NCBI Gene GI: 904134; NCBI Protein GI: 15677822; NCBI Protein Accession: NP_274986; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010981 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen [PubMed: 16825336]" ; rdfs:label "GNA1870" ; rdfs:seeAlso "Protegen ID: 273; NCBI Gene GI: 904318; NCBI Protein GI: 15677705; NCBI Protein Accession: NP_274866; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010982 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen as shown in some assays [PubMed: 16825336]" ; rdfs:label "GNA2091" ; rdfs:seeAlso "Protegen ID: 274; NCBI Gene GI: 903958; NCBI Protein GI: 15677911; NCBI Protein Accession: NP_275079; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010983 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective antigen as shown in some assays [PubMed: 16825336]" ; rdfs:label "GNA1030" ; rdfs:seeAlso "Protegen ID: 275; NCBI Gene GI: 903167; NCBI Protein GI: 15676917; NCBI Protein Accession: NP_274064; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010984 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A vaccine made by Hma from E. coli strain CFT073 and 536 induced protection to the infection of virulent strain CFT073 and 536, respectively, in the bladder in the CBA/J mice. [PubMed: 19806177]." ; rdfs:label "Hma" ; rdfs:seeAlso "Protegen ID: 278; NCBI Gene GI: 1037732; NCBI Protein GI: 26248334; NCBI Protein Accession: NP_754374; NCBITaxon: 199310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010985 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with IreA protects against urinary tract colinization by E.coli CFT073 and reduces colinization by E.coli 536 in the bladder of CBA/J mice [PubMed: 19806177]." ; rdfs:label "IreA" ; rdfs:seeAlso "Protegen ID: 279; NCBI Gene GI: 1037614; NCBI Protein GI: 26250982; NCBI Protein Accession: NP_757022; NCBITaxon: 199310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010986 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with IutA protects against urinary tract colinization by E.coli CFT073 in the bladders of CBA/J mice [PubMed: 19806177]." ; rdfs:label "IutA" ; rdfs:seeAlso "Protegen ID: 280; NCBI Gene GI: 1039578; NCBI Protein GI: 26249458; NCBI Protein Accession: NP_755498; NCBITaxon: 199310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010987 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Antibodies directed at the putative binding region of FimH (anti- s-FimH1-25) significantly reduced E. coli bladder infections in the experimental mouse model of urinary tract infections [PubMed: 9276729]." ; rdfs:label "FimH" ; rdfs:seeAlso "Protegen ID: 281; NCBI Gene GI: 948847; NCBI Protein GI: 16132141; NCBI Protein Accession: NP_418740; NCBITaxon: 511145" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010988 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Active immunization of BALB/c mice with IroN antigen in Freund's adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948 ]." ; rdfs:label "IroN from Escherichia coli" ; rdfs:seeAlso "Protegen ID: 282; NCBI Gene GI: 7379404; NCBI Protein GI: 222104801; NCBI Protein Accession: YP_002539290; NCBITaxon: 562" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010989 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Active immunization of BALB/c mice with C0393 antigen in Freund's adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948]." ; rdfs:label "C0393" ; rdfs:seeAlso "Protegen ID: 283; NCBI Gene GI: 1034958; NCBI Protein GI: 26246291; NCBI Protein Accession: NP_752330; NCBITaxon: 199310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010990 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Active immunization of BALB/c mice with C4424 antigen in Freund's adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948]." ; rdfs:label "C4424" ; rdfs:seeAlso "Protegen ID: 284; NCBI Gene GI: 1038067; NCBI Protein GI: 26250246; NCBI Protein Accession: NP_756286; NCBITaxon: 199310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010991 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Active immunization of BALB/c mice with recombinant E. coli protein C3389 antigen in Freund's adjuvant protects mice from lethal challenge with ExPEC strain S26 [PubMed: 17145948]." ; rdfs:label "C3389" ; rdfs:seeAlso "Protegen ID: 285; NCBI Gene GI: 1039252; NCBI Protein GI: 26249224; NCBI Protein Accession: NP_755264; NCBITaxon: 199310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010992 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "S. flexneri M90T is a colonisation-defective mutant with a transposon in fnr, which encodes a regulator of anaerobic metabolism. To establish whether FNR-mediated repression of spa32 and spa33 contributes to increased Shigella entry into cells in an anaerobic cabinet, recombinant M90T strains were constructed which contain spa32 and spa33 under the control of either their native promoters (M90Tp32/33) or promoters with disrupted FNR boxes (M90Tp#32/#33).The presence in M90T of spa32 and spa33 alleles that are not repressed by FNR led to IpaB secretion during anaerobic growth, and loss of the increased entry of Shigella into cells in an anaerobic cabinet [PubMed: 20436458]." ; rdfs:label "Spa32" ; rdfs:seeAlso "Protegen ID: 288; NCBI Gene GI: 876502; NCBI Protein GI: 13449098; NCBI Protein Accession: NP_085314; NCBITaxon: 424718" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010777, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010993 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Oral immunization of FaeG-expressing L. lactis exhibits a protective response against ETEC infection in mice [PubMed: 19277476]." ; rdfs:label "ECSE_P3-0034" ; rdfs:seeAlso "Protegen ID: 289; NCBI Gene GI: 7003192; NCBI Protein GI: 209921909; NCBI Protein Accession: YP_002295988; NCBITaxon: 409438" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010994 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium. Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae. Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex. Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P<0.01 for both animal models) [PubMed: 11083774]." ; rdfs:label "IpaB" ; rdfs:seeAlso "Protegen ID: 307; NCBI Protein GI: 22036246; NCBITaxon: 42897" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010777, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010995 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium. Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae. Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex. Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P<0.01 for both animal models) [PubMed: 11083774]." ; rdfs:label "IpaC" ; rdfs:seeAlso "Protegen ID: 308; NCBI Protein GI: 47056; NCBITaxon: 42897" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010777, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010996 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The invasiveness and virulence of Shigella spp. are largely due to the expression of plasmid-encoded virulence factors, among which are the invasion plasmid antigens (IpaB, IpaC, and IpaD). Recent observations have indicated that the Ipa proteins (IpaB, IpaC, and possibly IpaD) form a multiprotein complex capable of inducing the phagocytic event which internalizes the bacterium. Researchers isolated a complex of invasins and LPS from water-extractable antigens of virulent shigellae. Western blot analysis of the complex indicates that all of the major virulence antigens of Shigella, including IpaB, IpaC, and IpaD, and LPS are components of this macromolecular complex. Guinea pigs (keratoconjunctivitis model) or mice (lethal lung model) immunized intranasally with purivied invasin complex (invaplex) on days 0, 14, and 28 and challenged 3 weeks later with virulent shigellae were protected from disease (P<0.01 for both animal models) [PubMed: 11083774]." ; rdfs:label "IpaD" ; rdfs:seeAlso "Protegen ID: 309; NCBI Protein GI: 22036352; NCBITaxon: 42897" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010777, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010997 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Thirty-day-old chickens were immunized intramuscularly with purified IroN from Salmonella Typhimurium mixed with Freund's incomplete adjuvant; the chickens were then challenged intravenously with Salmonella Enteritidis. The mortality rate of immunized chickens was 10%. On the other hand, that of control chickens was 80% [PubMed: 20095157]." ; rdfs:label "IroN from Salmonella spp." ; rdfs:seeAlso "Protegen ID: 318; NCBI Protein GI: 259475459; NCBITaxon: 90371" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010776, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010998 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers evaluated the immunogenicity and protective efficacy of GroEL of Salmonella enterica serovar Typhi against lethal infection by S. typhi Ty2 in mice with or without adjuvants. Immunization of mice with GroEL-alone, GroEL + alum, and GroEL + CFA provided 70, 50 and 80% protection, respectively, against lethal challenge by S. typhi in mice. The present study shows that GroEL forms an ideal candidate molecule to develop a recombinant protein based vaccine against human typhoid [PubMed: 19851830]." ; rdfs:label "GroEL from Salmonella spp." ; rdfs:seeAlso "Protegen ID: 320; NCBI Gene GI: 1068458; NCBI Protein GI: 29144631; NCBI Protein Accession: NP_807973; NCBITaxon: 209261" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010776, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0010999 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The entire SopB and SifB genes were cloned into DNA vaccine vectors and were administered along with live attenuated Salmonella. It was found that SopB vaccination reduced the bacterial burden of organs by about 5-fold on day 4 and day 8 after challenge with virulent Salmonella and proved to be a more efficient vaccination strategy than live attenuated bacteria alone [PubMed: 19428891]." ; rdfs:label "SopB" ; rdfs:seeAlso "Protegen ID: 321; NCBI Protein GI: 54036439; NCBITaxon: 90371" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010776, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011000 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Oral immunization of mice with ZJ111/pcDNA3-SAG1 elicited specific humoral responses and stimulated proliferation of splenocytes (P<0.05). Mice immunized with ZJ111/pcDNA3-SAG1 displayed significant protection against an intraperitoneally challenge with 500 tachyzoite forms of T. gondii RH strain. Vaccination at 10(7) and 10(8)CFU per mice provided a 20% and 10% survival rate comparing 100% mortality of the non-immunized mice, exhibiting longer living time and better survival rate [PubMed: 18590785]." ; rdfs:label "SAG1 from Toxoplasma gondii" ; rdfs:seeAlso "Protegen ID: 326; NCBI Gene GI: 7900172; NCBI Protein GI: 237839159; NCBI Protein Accession: XP_002368877; NCBITaxon: 508771" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011001 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Modified YscF antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562]." ; rdfs:label "YscF from Y. pestis KIM 10" ; rdfs:seeAlso "Protegen ID: 338; NCBI Gene GI: 1149286; NCBI Protein GI: 31795470; NCBI Protein Accession: NP_857922; NCBITaxon: 187410" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011002 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Modified yopD antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562]." ; rdfs:label "YopD from Y. pestis KIM 10" ; rdfs:seeAlso "Protegen ID: 339; NCBI Gene GI: 1149313; NCBI Protein GI: 31795494; NCBI Protein Accession: NP_857949; NCBITaxon: 187410" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011003 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Modified yopO antigens were able to partially protect immunized mice at various levels against lethal challenge with Y. pestis KIM 1001 strain [PubMed: 18291562]." ; rdfs:label "YopO" ; rdfs:seeAlso "Protegen ID: 340; NCBI Gene GI: 5798322; NCBI Protein GI: 162417777; NCBI Protein Accession: YP_001604502; NCBITaxon: 349746" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011004 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intranasal immunization with flagellin and the F1 antigen was protective against intranasal challenge with virulent Y. pestis CO92, with 93 to 100% survival of immunized mice. Lastly, vaccination of cynomolgus monkeys with flagellin and a fusion of the F1 and V antigens of Y. pestis induced a robust antigen-specific IgG antibody response [PubMed: 16428759]." ; rdfs:label "YPMT1.84 (F1 capsule antigen)" ; rdfs:seeAlso "Protegen ID: 341; NCBI Gene GI: 1172839; NCBI Protein GI: 16082876; NCBI Protein Accession: NP_395430; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011005 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse model, YPO0606 (yapF) partially protected mice from infection with Y. pestis at a high challenge dosage (200x LD(50)) [PubMed: 19651863]." ; rdfs:label "YapF" ; rdfs:seeAlso "Protegen ID: 342; NCBI Gene GI: 1173449; NCBI Protein GI: 218927800; NCBI Protein Accession: YP_002345675; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011006 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse plague model, YPO1914 (irp7) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ; rdfs:label "Irp7" ; rdfs:seeAlso "Protegen ID: 343; NCBI Gene GI: 1174753; NCBI Protein GI: 218929030; NCBI Protein Accession: YP_002346905; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011007 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse plague model, YPO0612 may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ; rdfs:label "YPO0612" ; rdfs:seeAlso "Protegen ID: 344; NCBI Gene GI: 1173455; NCBI Protein GI: 218927806; NCBI Protein Accession: YP_002345681; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011008 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse plague model, YPO3119 (htpG) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ; rdfs:label "HtpG" ; rdfs:seeAlso "Protegen ID: 345; NCBI Gene GI: 1175934; NCBI Protein GI: 218930152; NCBI Protein Accession: YP_002348027; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011009 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse plague model, YPO3047 (ydeN) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ; rdfs:label "YdeN" ; rdfs:seeAlso "Protegen ID: 346; NCBI Gene GI: 1175868; NCBI Protein GI: 218930092; NCBI Protein Accession: YP_002347967; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011010 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse plague model, YPO1377 (lolA) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ; rdfs:label "LolA" ; rdfs:seeAlso "Protegen ID: 347; NCBI Gene GI: 1174218; NCBI Protein GI: 218928525; NCBI Protein Accession: YP_002346400; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011011 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse plague model, YPCD1.05c (yerA) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ; rdfs:label "YerA" ; rdfs:seeAlso "Protegen ID: 348; NCBI Gene GI: 1172650; NCBI Protein GI: 16082696; NCBI Protein Accession: NP_395142; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011012 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse plague model, YPO0420 may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ; rdfs:label "YPO0420" ; rdfs:seeAlso "Protegen ID: 349; NCBI Gene GI: 1173265; NCBI Protein GI: 218927621; NCBI Protein Accession: YP_002345496; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011013 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using a mouse plague model, YPO3720 (hpmB) may provide partial protection against challenge with a low dose (20 times the 50% lethal dose [20x LD(50)]) of Y. pestis [PubMed: 19651863]." ; rdfs:label "HpmB" ; rdfs:seeAlso "Protegen ID: 350; NCBI Gene GI: 1176539; NCBI Protein GI: 218930726; NCBI Protein Accession: YP_002348601; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011014 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study tested the efficacy of 2 proteins, Psn and a portion of LcrV in protecting mice against virulent Yersinia pestis challenge. Results show that the truncated LcrV protein delivered by RASV is sufficient to afford a full protective immune response in a mouse model of bubonic plague and the Psn protein afforded partial protection in a non-optimized system [PubMed: 17966435]." ; rdfs:label "Psn" ; rdfs:seeAlso "Protegen ID: 351; NCBI Gene GI: 1147351; NCBI Protein GI: 22126288; NCBI Protein Accession: NP_669711; NCBITaxon: 187410" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011015 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study evaluated the humoral immune response of mice that survived lethal Y. pestis aerosol challenge after antibiotic treatment. Results indicated that one of the predominant antibody response of mice surviving pneumonic plague after treatment with antibiotics was to yopH [PubMed: 10085037]." ; rdfs:label "YopH from Y. pestis CO92" ; rdfs:seeAlso "Protegen ID: 352; NCBI Gene GI: 1172712; NCBI Protein GI: 16082755; NCBI Protein Accession: NP_395201; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011016 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Complexes of YopB (pYV0055), YopD, and YopE (BDE) secreted by Yersinia pseudotuberculosis were purified by affinity chromatography and used as immunogens to determine if antibodies to the translocon could provide protection against Y. pestis in mice. The YopB protein or a complex of YopB and YopD (BD) was purified and determined by vaccination to be immunogenic in mice. Mice actively vaccinated with BD or passively vaccinated with anti-BD serum were protected against lethal challenge with F1(-) Y. pestis [PubMed: 18765742]." ; rdfs:label "pYV0055" ; rdfs:seeAlso "Protegen ID: 354; NCBI Gene GI: 2952948; NCBI Protein GI: 51593897; NCBI Protein Accession: YP_068464; NCBITaxon: 273123" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010796, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011017 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination of mice with deF1 DNA conferred protection against subcutaneous infection with the virulent Y. pestis Kimberley53 strain, even at challenge amounts as high as 4,000 50% lethal doses [PubMed: 12496187 ]." ; rdfs:label "Caf1 from Y. pestis" ; rdfs:seeAlso "Protegen ID: 355; NCBI Protein GI: 48621; NCBITaxon: 632" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011018 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following passive immunization, antisera partially protected infant rats from bacteremia resulting from intraperitoneal challenge with bacteria. As assessed by immunoblotting, pooled adult human sera contained antibodies reactive with P145. Following passive immunization, these antisera partially protected infant rats from bacteremia resulting from intraperitoneal challenge with bacteria. Antibody to P145 may contribute to protection against Brazilian purpuric fever [PubMed: 1937817]." ; rdfs:label "P145" ; rdfs:seeAlso "Protegen ID: 356" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011019 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The ApxI antigen is an important factor in the protection against Actinobacillus pleuropneumoniae serotype 5 infection; therefore, the protective immunity in mice following oral immunization with Saccharomyces cerevisiae expressing either ApxIA (group C) or ApxIIA (group D) alone or both (group E) was compared with that in two control groups (group A and B). The immunogenicity of the rApxIA antigen derived from the yeast was confirmed by a high survival rate and an ApxIA-specific IgG antibody response (p < 0.01) [PubMed: 17993753]." ; rdfs:label "ApxIA" ; rdfs:seeAlso "Protegen ID: 358; NCBI Protein GI: 312899; NCBITaxon: 715" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011020 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The levels of local and systemic antibodies specific to the Apx antigens were investigated in mice orally immunized with Apx antigen-expressing yeast. Specific IgA responses to ApxIA or ApxIIA in the intestines and lungs from mice immunized with yeast expressing Apx antigens were significantly higher than those in the control groups after the second and third immunizations, respectively (p < 0.05). All mice were monitored for up to 72 h after challenge with the MLD of an A. pleuropneumoniae field isolate. Overall, the final survival rates of the vaccinated groups were higher than those of the control groups at each time point [PubMed: 17993753]." ; rdfs:label "ApxIIA" ; rdfs:seeAlso "Protegen ID: 360; NCBI Protein GI: 52630374; NCBITaxon: 715" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011021 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following a booster vaccination, a significant (P < 0.05) IgG antibody response to the CP (cps5C), LPS, and HP was detected in the vaccinated pigs. The pigs vaccinated with the CP-HP and LPS-HP conjugates exhibited significantly less mortality (P < 0.05) and significantly greater weight gain (P < 0.001) than unvaccinated pigs. Vaccinated pigs exhibited significantly fewer and less extensive gross pulmonary lesions (P < 0.001) when compared with unvaccinated pigs [PubMed: 1455686]." ; rdfs:label "CP" ; rdfs:seeAlso "Protegen ID: 361" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011022 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following a booster vaccination, a significant (P < 0.05) IgG antibody response to the CP, LPS, and HP (APP7_1016) was detected in the vaccinated pigs. The pigs vaccinated with the CP-HP and LPS-HP conjugates exhibited significantly less mortality (P < 0.05) and significantly greater weight gain (P < 0.001) than unvaccinated pigs. Vaccinated pigs exhibited significantly fewer and less extensive gross pulmonary lesions (P < 0.001) when compared with unvaccinated pigs [PubMed: 1455686]." ; rdfs:label "APP7_1016" ; rdfs:seeAlso "Protegen ID: 362; NCBI Gene GI: 6398034; NCBI Protein GI: 190150285; NCBI Protein Accession: YP_001968810; NCBITaxon: 537457" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011024 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The aroA gene of A. salmonicida was cloned in Escherichia coli, and the nucleotide sequence was determined. Vaccination of brown trout with 10(7) CFU of A. salmonicida 644Rb aroA by intraperitoneal injection resulted in a 253-fold increase in the 50% lethal dose (LD50) compared with unvaccinated controls challenged with a virulent clinical isolate 9 weeks later [PubMed: 8478107]." ; rdfs:label "AroA" ; rdfs:seeAlso "Protegen ID: 366; NCBI Protein GI: 512545; NCBITaxon: 645" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010814, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011025 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Passive immunisation of Atlantic salmon with rainbow trout or rabbit anti-AsaP1 antisera conferred significant protection against challenge with a virulent A. salmonicida [Ref1011:Gudmundsdottir et al., 1997]" ; rdfs:label "AsaP1" ; rdfs:seeAlso "Protegen ID: 367; NCBI Gene GI: 4998702; NCBITaxon: 382245" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010814, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011026 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "RAP-1 (21B4) is a candidate for inclusion in a B. bovis vaccine based on its ability to induce partial protection in vaccinates, defined as a significant reduction in parasitemia upon challenge [PubMed: 1441189]." ; rdfs:label "RAP-1" ; rdfs:seeAlso "Protegen ID: 368; NCBI Gene GI: 5479143; NCBI Protein GI: 156087004; NCBI Protein Accession: XP_001610909; NCBITaxon: 484906" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010827, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011027 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Crude extracts of Babesia bovis parasites were systematically fractionated and tested in numerous sequential vaccination/challenge experiments in adult cattle. Two of these, GST-12D3 and GST-11C5, when used in combination were almost as protective as has been previously shown for the commercially available live attenuated vaccine [PubMed: 1441189]." ; rdfs:label "12D3" ; rdfs:seeAlso "Protegen ID: 371; NCBI Gene GI: 5478971; NCBI Protein GI: 156086656; NCBI Protein Accession: XP_001610737; NCBITaxon: 484906" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010827, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011028 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Crude extracts of Babesia bovis parasites were systematically fractionated and tested in numerous sequential vaccination/challenge experiments in adult cattle. A short fragment of the third antigen (21B4) has been shown to be protective [PubMed: 1441189]." ; rdfs:label "21B4" ; rdfs:seeAlso "Protegen ID: 373; NCBI Protein GI: 1246924; NCBITaxon: 5865" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010827, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011029 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study described the construction and evaluation of an adenovirus vaccine expressing domain 4 of Bacillus anthracis protective antigen, Ad.D4. Ad.D4 elicited antibodies to protective antigen 14 days after a single intramuscular injection, which were further increased upon boosting. Furthermore, two doses of Ad.D4 4 weeks apart were sufficient to protect 67% of mice from toxin challenge [PubMed: 16428747]." ; rdfs:label "PagA from B. anthracis" ; rdfs:seeAlso "Protegen ID: 374; NCBI Protein GI: 9280533; NCBITaxon: 1392" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010757, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011030 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A combination of the 69-kDa outer membrane protein and filamentous hemagglutinin (fhaB), both isolated from lymphocytosis promoting factor (LPF; pertussis toxin) minus mutants of Bordetella pertussis, is protective in the mouse intracerebral challenge potency (Kendrick) test [PubMed: 2056199]." ; rdfs:label "FhaB" ; rdfs:seeAlso "Protegen ID: 375; NCBI Protein GI: 3980256; NCBITaxon: 520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011031 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A study demonstrated that passive immunization with specific anti-B. pertussis adenylate cyclase antibodies or active immunization with purified B. pertussis secreted adenylate cyclase (cyaA) protect mice against a lethal respiratory challenge with B. pertussis or B. parapertussis. Results suggest that adenylate cyclase might be the primary cytotoxin responsible for mouse pulmonary lesions during respiratory tract infection with B. pertussis or with the related species B. parapertussis and is a protective antigen of B. pertussis [PubMed: 2622329]." ; rdfs:label "CyaA" ; rdfs:seeAlso "Protegen ID: 376; NCBI Protein GI: 580668; NCBITaxon: 520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011032 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model. These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ; rdfs:label "PtxD" ; rdfs:seeAlso "Protegen ID: 377; NCBI Protein GI: 225311181; NCBITaxon: 520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011033 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers constructed isogenic mutants of B. pertussis Tohama expressing the alleles ptxA1 or ptxA2 and prn1 or prn2 and compared the efficacies of an acellular pertussis vaccine against the mutants in a mouse model. While the vaccine was effective against all of the B. pertussis strains regardless of the allele expression pattern, the strain expressing ptxA1 and prn2 displayed a survival advantage over the other strains [PubMed: 20357056]." ; rdfs:label "Prn" ; rdfs:seeAlso "Protegen ID: 378; NCBI Gene GI: 2664290; NCBI Protein GI: 33592195; NCBI Protein Accession: NP_879839; NCBITaxon: 257313" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011034 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model. These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ; rdfs:label "PtxA" ; rdfs:seeAlso "Protegen ID: 379; NCBI Gene GI: 2665068; NCBI Protein GI: 33594638; NCBI Protein Accession: NP_882282; NCBITaxon: 257313" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011035 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A soluble fraction obtained from Bordetella pertussis was evaluated as adjuvant for the pertussis component of the Diphtheria-Pertussis-Tetanus (DPT) vaccine. High levels of antibodies were induced, and a 78% protection rate of mice challenged with live B. pertussis was observed. Two proteins were identified as the 73 kDa N-terminal alpha-domain of BrkA autotransporter protein and the Cpn60/60 kDa chaperonin. Both stimulated antibodies against pertussis and induced a 42% protection rate against the challenge [PubMed: 17011680]." ; rdfs:label "Cpn60" ; rdfs:seeAlso "Protegen ID: 382; NCBI Protein GI: 968920; NCBITaxon: 520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011036 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A soluble fraction obtained from Bordetella pertussis was evaluated as adjuvant for the pertussis component of the Diphtheria-Pertussis-Tetanus (DPT) vaccine. High levels of antibodies were induced, and a 78% protection rate of mice challenged with live B. pertussis was observed. Two proteins were identified as the 73 kDa N-terminal alpha-domain of BrkA autotransporter protein and the Cpn60/60 kDa chaperonin. Both stimulated antibodies against pertussis and induced a 42% protection rate against the challenge [PubMed: 17011680]." ; rdfs:label "BrkA" ; rdfs:seeAlso "Protegen ID: 383; NCBI Protein GI: 562026; NCBITaxon: 520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011037 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model. These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ; rdfs:label "PtxB" ; rdfs:seeAlso "Protegen ID: 384; NCBI Protein GI: 225311180; NCBITaxon: 520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011038 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model. These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ; rdfs:label "PtxC" ; rdfs:seeAlso "Protegen ID: 385; NCBI Protein GI: 225311183; NCBITaxon: 520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011039 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized with PTx vaccine on day 6 of life and then challenged with B. pertussis using the aerosol challenge model. These primed mice were significantly better protected against leukocytosis, weight loss, and proliferation of B. pertussis in the lungs following aerosol challenge than the nonprimed group. This protection correlated with levels of anti-PT antibody in serum present on the day of aerosol challenge [PubMed: 12117973]." ; rdfs:label "PtxE" ; rdfs:seeAlso "Protegen ID: 386; NCBI Protein GI: 225311182; NCBITaxon: 520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010847, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011040 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protection against a BHV-1 challenge was obtained in calves immunized with the plasmid encoding tgD-VP22 (UL49), as shown by significant reductions in viral excretion [PubMed: 15650221]." ; rdfs:label "UL49 from Bovine herpesvirus 1" ; rdfs:seeAlso "Protegen ID: 389; NCBI Gene GI: 1487397; NCBI Protein GI: 9629826; NCBI Protein Accession: NP_045310; NCBITaxon: 10320" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010802, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011041 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Calves were injected intranasally with either AdCMVgC or AdCMVgD (US6) or a combination of these two recombinants or a commercially available live vaccine for comparison. The highest BHV-1 neutralizing antibody titres were obtained with AdCMVgD (US6) followed by the live vaccine and to a lower extent with the combination of the two recombinants. Calves were protected against intranasal BHV-1 challenge performed 3 weeks after the second immunization [PubMed: 11818166]." ; rdfs:label "US6 from Bovine herpesvirus 1" ; rdfs:seeAlso "Protegen ID: 390; NCBI Gene GI: 1487406; NCBI Protein GI: 9629886; NCBI Protein Accession: NP_045370; NCBITaxon: 10320" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010802, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011042 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization of calves with truncated gpI (US7) protein induced gpI-specific nasal IgA, IgG1, serum neutralizing antibodies and gpI-specific peripheral lymphocyte proliferation. All immunized calves were protected from clinical disease after BHV-1 challenge. Further, nine of ten immunized calves had no intranasal viral shedding [PubMed: 8147097]." ; rdfs:label "US7" ; rdfs:seeAlso "Protegen ID: 392; NCBI Gene GI: 4783432; NCBI Protein GI: 9629887; NCBI Protein Accession: NP_045371; NCBITaxon: 10320" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010802, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011043 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A DNA vaccine expressing glycoprotein C (gC, UL44) of bovine herpesvirus-1 (BHV-1) was evaluated for inducing immunity in bovines. Results indicate that DNA immunization with gC could induce neutralizing antibody and lymphoproliferative responses with BHV-1 responsive memory B cells in bovines. However, the immunity developed sufficient for only partial protection against BHV-1 challenge [PubMed: 11182496]." ; rdfs:label "UL44 from Bovine herpesvirus 1" ; rdfs:seeAlso "Protegen ID: 393; NCBI Gene GI: 4783424; NCBI Protein GI: 9629830; NCBI Protein Accession: NP_045314; NCBITaxon: 10320" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010802, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011044 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively. The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively. The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 [PubMed: 18206008]." ; rdfs:label "CadF" ; rdfs:seeAlso "Protegen ID: 396; NCBI Protein GI: 4704601; NCBITaxon: 197" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011045 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively. The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively. The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 [PubMed: 18206008]." ; rdfs:label "Peb1A" ; rdfs:seeAlso "Protegen ID: 397; NCBI Protein GI: 112360246; NCBITaxon: 192222" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011046 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice were immunized intranasally with two doses of 3 to 50 microgram of MBP-FlaA. The protective efficacies of a 50 microgram of MBP-FlaA plus LT(R192G) dose against disease symptoms and intestinal colonization were 81.1 and 84%, respectively. When mice which had been immunized with 50 microgram of MBP-FlaA plus LT(R192G) intranasally were challenged orally with 8 x 10(10), 8 x 10(9), or 8 x 10(8) cells of strain 81-176, the protective efficacies against intestinal colonization at 7 days postinfection were 71.4, 71.4, and 100%, respectively [PubMed: 10531231]." ; rdfs:label "FlaA from C. jejuni 81-176" ; rdfs:seeAlso "Protegen ID: 398; NCBI Gene GI: 4682159; NCBI Protein GI: 121612545; NCBI Protein Accession: YP_001000997; NCBITaxon: 354242" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011047 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model. Immunization with FspA1 resulted in 57.8% protection without adjuvant or 63.8% protection with adjuvant against homologous challenge with 81-176 [PubMed: 18426878]." ; rdfs:label "FspA1" ; rdfs:seeAlso "Protegen ID: 399; NCBI Protein GI: 116292649; NCBITaxon: 197" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011048 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model. All three proteins were immunogenic, FlaC provided an 18% protection against disease from C. jejuni 81-176 [PubMed: 18426878]." ; rdfs:label "FlaC" ; rdfs:seeAlso "Protegen ID: 400; NCBI Gene GI: 4682885; NCBI Protein GI: 121612344; NCBI Protein Accession: YP_001000416; NCBITaxon: 354242" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011049 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunogenicity and protective efficacy of three Campylobacter jejuni flagellum-secreted proteins, FlaC, FspA1, and FspA2, were compared by use of a mouse model. Immunization with FspA2 provided 38.4% (without adjuvant) or 47.2% (with adjuvant) protection against disease from homologous challenge with CG8486 [PubMed: 18426878]." ; rdfs:label "FspA2" ; rdfs:seeAlso "Protegen ID: 409; NCBI Protein GI: 116292677; NCBITaxon: 197" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010765, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011050 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A DNA vaccination trial was performed on sheep to determine whether vaccination with bovine leukemia virus (BLV) transactivator Tax DNA is effective against BLV infection. Results showed higher levels of virus titers in control sheep than those in Tax-vaccinated sheep. Higher levels of IFN-gamma mRNA expression have been demonstrated in vaccinated sheep after the challenge. These results suggested that Th1 type immune response induced by Tax DNA vaccine inhibited BLV propagation in vaccinated sheep at the early phase of infection [PubMed: 14665749]." ; rdfs:label "Tax" ; rdfs:seeAlso "Protegen ID: 410; NCBI Gene GI: 2760848; NCBI Protein GI: 9626228; NCBI Protein Accession: NP_056895; NCBITaxon: 11901" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010797, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011051 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The bovine leukemia virus (BLV) envelope gene encoding extracellular glycoprotein gp51 (encoded by env gene) and transmembrane glycoprotein gp30 was cloned into a vehicle expression vector under the human cytomegalovirus (CMV) intermediate early promoter. The intramuscular injection of this plasmid vector generated a cellular immune response. Seven out of ten cows vaccinated with the DNA construct resisted a drastic challenge [PubMed: 10824867]." ; rdfs:label "Env/Rex/Tax" ; rdfs:seeAlso "Protegen ID: 411; NCBI Gene GI: 2760849; NCBI Protein GI: 9626230; NCBI Protein Accession: NP_056898; NCBITaxon: 11901" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010797, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011052 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Young mink kits (n=8) were vaccinated with DNA plasmids encoding the viral haemagglutinin protein (H) of a vaccine strain of Canine distemper virus (CDV). The mink were protected against viraemia, lymphopenia, clinical disease and changes in the percentage of IFN-gamma producing peripheral blood leucocytes after challenge inoculation with a recent wild type strain of CDV. Essentially, these results demonstrate that early life DNA vaccination with the H gene of a CDV vaccine strain induced robust protective immunity against a recent wild type CDV [PubMed: 19596418]." ; rdfs:label "CDVgp6 haemagglutinin protein H" ; rdfs:seeAlso "Protegen ID: 412; NCBI Gene GI: 1489792; NCBI Protein GI: 9630651; NCBI Protein Accession: NP_047206; NCBITaxon: 11232" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010809, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011053 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study reports the engineering and the characterization of two replication-competent canine adenovirus type 2 (CAV2)-based vaccines expressing, respectively, the CDV hemagglutinin (HA) and fusion (F) antigens (CDVgp5). We first demonstrated that the intranasal vaccination with a mixture of both recombinant CAV2s provides an excellent level of protection in seronegative puppies, confirming the value of replication-competent adenovirus-based vectors for mucosal vaccination [PubMed: 12297394]." ; rdfs:label "CDVgp5" ; rdfs:seeAlso "Protegen ID: 413; NCBI Gene GI: 1489793; NCBI Protein GI: 9630650; NCBI Protein Accession: NP_047205; NCBITaxon: 11232" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010809, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011054 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A vaccine based upon a recombinant plant virus (CPMV-PARVO1), displaying a peptide derived from the VP2 capsid protein of canine parvovirus (CPV), has previously been described. To date, studies with the vaccine have utilized viable plant chimaeric particles (CVPs). Results show that the inactivated CVP is able to protect dogs from a lethal challenge with CPV following parenteral immunization with the vaccine. Dogs immunized with the inactivated CPMV-PARVO1 in adjuvant displayed no clinical signs of disease and shedding of CPV in faeces was limited following CPV challenge. [PubMed: 11395200]." ; rdfs:label "VP2 from Canine parvovirus" ; rdfs:seeAlso "Protegen ID: 414; NCBI Gene GI: 1489588; NCBITaxon: 10788" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010807, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011055 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "This study shows that a plasmid DNA (pGT36VP1) encoding the full length VP1 region of canine parvovirus (CPV) induces immunity that protects dogs against challenge with virulent virus [PubMed: 9569471]." ; rdfs:label "VP1 from Canine parvovirus" ; rdfs:seeAlso "Protegen ID: 415; NCBI Gene GI: 1489587; NCBITaxon: 10788" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010807, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011056 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. DNA pol III Gamma and Tau (CP #1, dnaX) was found to be protective. CP #1 (dnaX) was more protective than the live-vaccine, positive control. [PubMed: 15811648]." ; rdfs:label "DnaX" ; rdfs:seeAlso "Protegen ID: 416; NCBI Protein GI: 62148024; NCBITaxon: 218497" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011057 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Glu-tRNA Gln Amidotransferase (CP #2, gatC) was found to be protective. Three of the clones (CP #1) elicited protection that was statistically higher than the unvaccinated control, which has high variance [PubMed: 15811648]." ; rdfs:label "GatC" ; rdfs:seeAlso "Protegen ID: 417; NCBI Protein GI: 62184917; NCBITaxon: 218497" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011058 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Protective clone CP #4 (OMP90A, pomp90A) was diluted 1/2000 in a non-protective sublibrary pool of clones. This CP #4-spiked sublibrary conferred protection. Five clones were significantly more protective than the genes encoding fewer than 50 amino acids (CP #1 and 7, p-value of less than 0.05 when comparing lung weights). [PubMed: 15811648]." ; rdfs:label "Pomp90A" ; rdfs:seeAlso "Protegen ID: 418; NCBI Protein GI: 187438939; NCBITaxon: 83555" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011059 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. CP #5 (Transglycolase/transpeptidase, CAB049 putative penicillin-binding protein) was significantly more protective than the genes encoding fewer than 50 amino acids (p-value of less than 0.05 when comparing lung weights). The chlamydial loads generally tracked with protection and the most protective genes were significantly lower than in unvaccinated controls (p < 0.05 in the Mannhitney U-test for genes CP #1, 2, 4, 9, 10) [PubMed: 15811648]." ; rdfs:label "CAB049 putative penicillin-binding protein" ; rdfs:seeAlso "Protegen ID: 419; NCBI Protein GI: 62184696; NCBITaxon: 218497" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011060 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. CP #7 (omlA) was significantly more protective than the genes encoding fewer than 50 amino acids (p-value of less than 0.05 when comparing lung weights). The chlamydial loads generally tracked with protection and the most protective genes were significantly lower than in unvaccinated controls (p < 0.05 in the Mannhitney U-test for genes CP #1, 2, 4, 9, 10) [PubMed: 15811648]." ; rdfs:label "OmlA" ; rdfs:seeAlso "Protegen ID: 420; NCBI Protein GI: 62184824; NCBITaxon: 218497" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011061 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Genetic immunization was used to functionally test the genes of C. abortus as vaccines in a mouse challenge system. Of the 14 individually tested clones, CP #1 through CP #9 had positive relative protection scores. CP #8 (CAB613, Oligopeptidase) was found to confer protection [PubMed: 15811648]." ; rdfs:label "CAB613 putative peptidase" ; rdfs:seeAlso "Protegen ID: 421; NCBI Protein GI: 62185225; NCBITaxon: 218497" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010817, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011062 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Animals vaccinated with Gam82 and challenged with E. maxima showed lower oocyst shedding and reduced intestinal pathology compared with non-vaccinated and parasite-challenged animals. Gam82 vaccination also stimulated the production of antigen-specific serum antibodies and induced greater levels of IL-2 and IL-15 mRNAs compared with non-vaccinated controls. These results demonstrate that the Gam82 recombinant protein protects against E. maxima and augments humoral and cell-mediated immunity [PubMed: 20178868]." ; rdfs:label "Gam82" ; rdfs:seeAlso "Protegen ID: 457; NCBI Protein GI: 38565038; NCBITaxon: 5804" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010833, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011063 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Birds vaccinated with Eimeria tenella microneme recombinant gene (EtMIC2) and encoded protein developed protective immunity against infection by E. tenella as assessed by significantly increased body weight gain and decreased fecal oocyst shedding compared with non-vaccinated controls. Vaccination with the EtMIC2 gene also led to protective immunity against infection by E. acervulina, but not E. maxima [PubMed: 15882535]." ; rdfs:label "MIC2" ; rdfs:seeAlso "Protegen ID: 459; NCBI Protein GI: 225579627; NCBITaxon: 5802" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010823, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011064 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Two recombinant Mycobacterium bovis BCG (rBCG) strains carrying the Eimeria tenella rhomboid gene (Rho) delivered by extrachromosomal vector pMV261 and integrative vector pMV361 were evaluated for their ability to protect chickens against E. tenella challenge. Chickens were immunized intranasal with BCG, rBCG pMV261-Rho, or rBCG pMV361-Rho twice at a 2-week interval. All the recombinant BCG immunized chickens developed specific immune responses, and there was a significant increases of the percentages of CD4(+) and CD8(+) cells compared to the control (P<0.05). Challenge experiments demonstrated that the two rBCG strains could provide significant protection against E. tenella challenge [PubMed: 19117681]." ; rdfs:label "Rho" ; rdfs:seeAlso "Protegen ID: 460; NCBI Protein GI: 84043169; NCBITaxon: 5802" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010823, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011065 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The immunization procedure of DNA vaccine pcDNA-TA4-IL-2 of Eimeria tenella, including route, dose, time of immunization and age of primary immunization of chicken, was optimized. results illustrated that 25 microg was the optimal dose and intramuscular injection was the most effective route to induce protective immunity in Chinese Yellow chickens [PubMed: 19019543]." ; rdfs:label "TA4" ; rdfs:seeAlso "Protegen ID: 461; NCBI Protein GI: 84783094; NCBITaxon: 5802" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010823, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011066 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The Eimeria tenella antigen gene (3-1E) and chicken interferon gamma gene (ChIFN-gamma) were subcloned into the mammalian expression vector proVAX forming the plasmids proE and prol. After challenge the proIE-vaccinated chickens showed protective immunity as demonstrated by significantly reduced oocyst shedding [PubMed: 17274297]." ; rdfs:label "3-1E" ; rdfs:seeAlso "Protegen ID: 463; NCBI Protein GI: 126362934; NCBITaxon: 5802" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010823, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011067 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A cDNA clone derived from sporulated oocysts of Eimeria tenella and encoding the expression product GX3262 was identified using a monoclonal antibody raised against Eimeria acervulina sporozoites. After challenge with an experimental E. tenella infection, the greatest degree of protection in immunized broiler chickens was seen after only a single immunization of 2-day-old birds with a live recombinant E. coli preparation [PubMed: 2659532]." ; rdfs:label "GX3262" ; rdfs:seeAlso "Protegen ID: 464; NCBI Protein GI: 102304; NCBITaxon: 5802" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010823, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011068 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study describes experiments which demonstrate that the vaccine, (EURIFEL FeLV; Merial) that expresses the FeLV env and gag protective genes, is effective against any oronasal FeLV challenge. The protection was shown to be solid against an oronasal challenge one year after the initial vaccination, and was effective against a very severe 'in-contact' challenge [PubMed: 12934796]." ; rdfs:label "Env" ; rdfs:seeAlso "Protegen ID: 465; NCBI Gene GI: 1491868; NCBI Protein GI: 9630709; NCBI Protein Accession: NP_047256; NCBITaxon: 11768" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010806, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011069 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The vaccine, (EURIFEL FeLV; Merial) that expresses the FeLV env and gag protective genes, is effective against any oronasal FeLV challenge. The protection was shown to be solid against an oronasal challenge one year after the initial vaccination, and was effective against a very severe 'in-contact' challenge [PubMed: 12934796]." ; rdfs:label "Gag" ; rdfs:seeAlso "Protegen ID: 466; NCBI Protein GI: 323916; NCBITaxon: 11768" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010806, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011070 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intranasal immunization of HLA-DR4 tg mice with the single antigen FopB from F. tularensis subsp. novicida conferred significant protection against lethal pulmonary challenge with an F. tularensis subsp. holarctica live vaccine strain." ; rdfs:label "FopB" ; rdfs:seeAlso "Protegen ID: 468; NCBI Gene GI: 4547777; NCBI Protein GI: 118496734; NCBI Protein Accession: YP_897784; NCBITaxon: 401614" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011071 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intranasal vaccination with KKF235 (F. tularensis subsp. novicida mutant (DeltaiglB) ) protected mice from subsequent homotypic challenge with U112 as well as heterotypic challenge with F. tularensis subsp. holarctica (LVS). Most significantly, oral immunization with KKF235 protected mice from a highly lethal subsp. tularensis (SCHU S4) pulmonary challenge [PubMed: 20016043]." ; rdfs:label "IglB" ; rdfs:seeAlso "Protegen ID: 469; NCBI Gene GI: 4548125; NCBI Protein GI: 118497903; NCBI Protein Accession: YP_898953; NCBITaxon: 401614" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011072 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with rLm/iglC were protected against lethal challenge with F. tularensis LVS administered by the intranasal route, a route chosen to mimic airborne infection, and, most importantly, against aerosol challenge with the highly virulent Type A F. tularensis SchuS4 strain [PubMed: 19126421]." ; rdfs:label "IglC1" ; rdfs:seeAlso "Protegen ID: 470; NCBI Gene GI: 3191591; NCBI Protein GI: 56708413; NCBI Protein Accession: YP_170309; NCBITaxon: 177416" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011073 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with rLm/iglC were protected against lethal challenge with F. tularensis LVS administered by the intranasal route, a route chosen to mimic airborne infection, and, most importantly, against aerosol challenge with the highly virulent Type A F. tularensis SchuS4 strain [PubMed: 19126421]." ; rdfs:label "IglC2" ; rdfs:seeAlso "Protegen ID: 471; NCBI Gene GI: 3191814; NCBI Protein GI: 56708721; NCBI Protein Accession: YP_170617; NCBITaxon: 177416" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011074 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with WbtI(G191V) protected mice against a relatively low-dose intraperitoneal challenge with LVS (F. tularensis subspecies holarctica live vaccine strain), but was less protective against a high-dose challenge [PubMed: 17768257]." ; rdfs:label "WbtI" ; rdfs:seeAlso "Protegen ID: 472; NCBI Gene GI: 5522688; NCBI Protein GI: 156502002; NCBI Protein Accession: YP_001428067; NCBITaxon: 458234" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011075 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers have shown that mice that had been immunized with purified heat shock protein 60 (Hsp60, groEL) isolated from Francisella tularensis were protected against a subsequent challenge with some strains of the bacterium [PubMed: 15213156]." ; rdfs:label "GroEL from Francisella tularensis" ; rdfs:seeAlso "Protegen ID: 473; NCBI Protein GI: 282159959; NCBITaxon: 510831" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011076 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A 17-kDa lipoprotein, TUL4, of the facultative intracellular bacterium Francisella tularensis is one of several membrane proteins that induce an in vitro response in T cells from F. tularensis-primed humans. When mice were immunized with S. typhimurium chi 4072(pTUL4-15), some animals showed an antibody response and a T-cell response to TUL4. The present study demonstrated that the 17-kDa lipoprotein TUL4 of F. tularensis is involved in a protective immunity to tularemia [PubMed: 1612751]." ; rdfs:label "TUL4" ; rdfs:seeAlso "Protegen ID: 474; NCBI Protein GI: 148688; NCBITaxon: 263" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011077 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "C57BL/6 mice were vaccinated intranasally (i.n.) with the sodB(Ft) mutant and challenged i.n. with lethal doses of F. tularensis SchuS4. SodB(Ft) vaccinated mice following SchuS4 challenge exhibited significantly reduced bacterial burden in lungs, liver and spleen, regulated production of pro-inflammatory cytokines and less severe histopathological lesions compared to the LVS vaccinated mice. The sodB(Ft) vaccination induced a potent humoral immune response and protection against SchuS4 required both CD4 and CD8 T cells in the vaccinated mice [PubMed: 18692537]." ; rdfs:label "SodB from F. tularensis SCHU S4" ; rdfs:seeAlso "Protegen ID: 475; NCBI Gene GI: 3190713; NCBI Protein GI: 56707247; NCBI Protein Accession: YP_169143; NCBITaxon: 177416" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011078 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Anti-FopA MAbs protected 90% of nave C3H/HeN mice from lethal challenge with F. tularensis LVS when administered prophylactically as well as therapeutically [PubMed: 19176692]." ; rdfs:label "FopA" ; rdfs:seeAlso "Protegen ID: 476; NCBI Gene GI: 4306351; NCBI Protein GI: 115315051; NCBI Protein Accession: YP_763774; NCBITaxon: 393011" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011079 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Anti-lpnA MAbs conferred significant, although not complete, protection of nave C3H/HeN mice from lethal challenge with F. tularensis LVS when administered therapeutically [PubMed: 19176692]." ; rdfs:label "LpnA" ; rdfs:seeAlso "Protegen ID: 477; NCBI Gene GI: 3191792; NCBI Protein GI: 56708002; NCBI Protein Accession: YP_169898; NCBITaxon: 177416" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010760, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011080 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The gene encoding the full length cyst wall protein-2 (CWP2) from Giardia lamblia was subcloned into the pCDNA3 mammalian expression vector and stably introduced into S. typhimurium STM1. Challenge infection with live Giardia muris cysts revealed that mice receiving the CWP2-encoding DNA vaccine were able to reduce cyst shedding by approximately 60% compared to control mice [PubMed: 17996337]." ; rdfs:label "CWP2" ; rdfs:seeAlso "Protegen ID: 479; NCBI Gene GI: 5703171; NCBI Protein GI: 159120052; NCBI Protein Accession: XP_001710242; NCBITaxon: 50803" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010829, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011081 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Rats vaccinated with PD (hpd) cleared NT H. influenzae better after middle ear and pulmonary bacterial challenge, and chinchillas vaccinated with PD showed significant protection against NT H. influenzae-dependent acute otitis media. In a clinical trial involving children, PD was used as an antigenically active carrier protein in an 11-valent pneumococcal conjugate investigational vaccine; significant protection was achieved against acute otitis media not only caused by pneumococci but also caused by NT H. influenzae [PubMed: 18230042]." ; rdfs:label "Hpd" ; rdfs:seeAlso "Protegen ID: 480; NCBI Protein GI: 148971; NCBITaxon: 727" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011082 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In a chinchilla model of otitis media, initial screening of P5-fimbrin, delivered singly or in combination with either Freund's adjuvant or alum, indicated that augmented bacterial clearance from the nasopharynx, the middle ears, or both anatomical sites could be induced by parenteral immunization with P5-fimbrin combined with lipoprotein D, lipoprotein D alone, or the synthetic chimeric peptide LB1 (derived from P5-fimbrin), respectively [PubMed: 10338477]." ; rdfs:label "OmpP5" ; rdfs:seeAlso "Protegen ID: 482; NCBI Gene GI: 3430592; NCBI Protein GI: 68249712; NCBI Protein Accession: YP_248824; NCBITaxon: 281310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011083 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Purified rD15 was found to be highly immunogenic in mice, guinea pigs, and rabbits, and passive transfer of anti-rD15 antibodies protected infant rats from challenge with H. influenzae type b or type a in infant rat models of bacteremia [PubMed: 9284140]." ; rdfs:label "D15" ; rdfs:seeAlso "Protegen ID: 483; NCBI Gene GI: 3430379; NCBI Protein GI: 68249503; NCBI Protein Accession: YP_248615; NCBITaxon: 281310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011084 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Rabbit antibody prepared against P2 from one strain was cross-reactive with P2 isolated from the other two heterologous strains by Western blot. This antibody passively protected infant rats against type b Haemophilus infection caused by the homologous organism, but not against challenge by a strain with the heterologous 36,500 mol wt P2 protein [PubMed: 6603479]." ; rdfs:label "OmpP2" ; rdfs:seeAlso "Protegen ID: 485; NCBI Gene GI: 3429565; NCBI Protein GI: 68248747; NCBI Protein Accession: YP_247859; NCBITaxon: 281310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011085 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Seoul virus (SEOV) is one of the four known hantaviruses causing hemorrhagic fever with renal syndrome (HFRS). A replication-competent recombinant canine adenovirus type 2 expressing the Gc protein of SEOV (rCAV-2-Gc) in BALB/c mice induced complete protection against a intensive infectious challenge with ~1,000 50% infective doses (ID50) for SEOV strain CC-2 [PubMed: 20181748]." ; rdfs:label "Gc" ; rdfs:seeAlso "Protegen ID: 486; NCBI Protein GI: 284157806; NCBITaxon: 11608" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011086 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study used a deer mouse infection model to test the protective efficacy of genetic vaccine candidates for Sin Nombre (SN) virus that were known to provoke immunological responses in BALB/c mice. Protective epitopes were localized in each of four overlapping cDNA fragments that encoded portions of the SN virus G1 glycoprotein antigen; the nucleocapsid gene also was protective [PubMed: 12075094]." ; rdfs:label "G1" ; rdfs:seeAlso "Protegen ID: 487; NCBI Protein GI: 1113859; NCBITaxon: 37705" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011087 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study used a deer mouse infection model to test the protective efficacy of genetic vaccine candidates for Sin Nombre (SN) virus that were known to provoke immunological responses in BALB/c mice. Protective epitopes were localized in each of four overlapping cDNA fragments that encoded portions of the SN virus G1 glycoprotein antigen; the nucleocapsid gene (SNVsSgp1) also was protective [PubMed: 12075094]." ; rdfs:label "SNVsSgp1" ; rdfs:seeAlso "Protegen ID: 489; NCBI Gene GI: 2943142; NCBI Protein GI: 38371726; NCBI Protein Accession: NP_941975; NCBITaxon: 37705" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011088 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "To investigate the ability of recombinant N (rN, nucleocapsid proteins) from different hantaviruses to elicit cross-protection, we immunized bank voles with rN from Puumala (PUUV), Topografov (TOPV), Andes (ANDV), and Dobrava (DOBV) viruses and subsequently challenged them with PUUV. All animals immunized with PUUV (PUUVsSgp1) and TOPV rN were completely protected [PubMed: 12050380]." ; rdfs:label "PUUVsSgp1" ; rdfs:seeAlso "Protegen ID: 490; NCBI Gene GI: 2943083; NCBI Protein GI: 38371721; NCBI Protein Accession: NP_941984; NCBITaxon: 11604" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011089 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "To investigate the ability of recombinant N (rN, nucleocapsid proteins) from different hantaviruses to elicit cross-protection, we immunized bank voles with rN from Puumala (PUUV), Topografov (TOPV), Andes (ANDV), and Dobrava (DOBV) viruses and subsequently challenged them with PUUV. All animals immunized with PUUV and TOPV rN were completely protected [PubMed: 12050380]." ; rdfs:label "N protein [Topografov virus]" ; rdfs:seeAlso "Protegen ID: 491; NCBI Protein GI: 4757106; NCBITaxon: 83192" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011090 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers vaccinated hamsters with a vaccinia virus-vectored vaccine expressing the M and the S segments of Hantaan (HTN) virus and challenged them with HTN, Seoul (SEO), or Puumala (PUU) virus. Study found that vaccinated hamsters, challenged with HTN or SEO virus, were neither viremic nor had evidence of virus in their lungs or kidneys [PubMed: 7666542]." ; rdfs:label "M Segment" ; rdfs:seeAlso "Protegen ID: 492; NCBI Protein GI: 1389703; NCBITaxon: 11599" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011091 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Passive transfer of spleen cells from mice immunized with rNP (HTNVsSgp1) conferred partial protection or prolongation of time to death from fatal Hantaan virus infection in suckling mice which were challenged with Hantaan virus at 40 LD50 (survival rate: 43%) or 4 LD50 (survival rate: 43%) [PubMed: 8517793]." ; rdfs:label "HTNVsSgp1" ; rdfs:seeAlso "Protegen ID: 493; NCBI Gene GI: 2943078; NCBI Protein GI: 38371711; NCBI Protein Accession: NP_941977; NCBITaxon: 11599" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011092 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Nonreplicating adenovirus (Ad) vectors that express Andes hantavirus (ANDV) nucleocapsid protein (AdN, ANDVsSgp1) or glycoproteins (AdG(N) and AdG(C)) were constructed . When administered once, all three Ad vectors, individually or in combination, elicited a robust immune response that protected Syrian hamsters from a lethal ANDV infection that mimics the pulmonary disease seen in humans. No vaccinated animal died, and there were no obvious clinical signs of disease [PubMed: 19403663]." ; rdfs:label "ANDVsSgp1" ; rdfs:seeAlso "Protegen ID: 494; NCBI Gene GI: 991232; NCBI Protein GI: 19744950; NCBI Protein Accession: NP_604471; NCBITaxon: 46607" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010768, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011093 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study compared a current HBV vaccine that contains recombinant hepatitis B surface antigen HBsAg) adsorbed to alum in chimpanzees, with two novel vaccine strategies that have proven superior to the current vaccine in mice. All animals receiving either control or CpG-containing subunit vaccines at 0 and 4 weeks attained titers of HBsAg-specific antibody (anti-HBs) considered protective (> or =10 mIU/ml) and were indeed protected from challenge at 8 weeks with 10(3.5) 50% chimp infectious doses (CID(50)) of intravenous HBV [PubMed: 16428890]." ; rdfs:label "Hepatitis B surface antigen" ; rdfs:seeAlso "Protegen ID: 495; NCBI Protein GI: 128168861; NCBITaxon: 10407" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010781, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011094 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The immunological protection of pVAX-PS, a DNA vaccine, was assessed in the tree shrews model. pVAX-PS was constructed by inserting the gene encoding the middle (pre-S2 plus S) envelope protein of HBV into a plasmid vector pVAX1. Results indicated that pVAX-PS immunization could induce remarkable humoral immune response and prevent the experimental tree shrews from infection of HBV [PubMed: 12932306]." ; rdfs:label "PreS2 middle surface protein" ; rdfs:seeAlso "Protegen ID: 496; NCBI Protein GI: 113207330; NCBITaxon: 10407" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010781, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011095 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunisation with a plasmid encoding the DHBV large (L) envelope protein (HBVgp2 pre-S1/pre-S2/S) induced a strong, specific, highly neutralising and long-lasting anti-preS humoral response in uninfected ducks. Importantly, maternal antibodies elicited by such DNA immunisation were vertically transmitted and protected progeny against viral challenge [PubMed: 12531335]." ; rdfs:label "HBVgp2 pre-S1/pre-S2/S" ; rdfs:seeAlso "Protegen ID: 497; NCBI Gene GI: 944569; NCBI Protein GI: 77680739; NCBI Protein Accession: YP_355333; NCBITaxon: 10407" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010781, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011096 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The herpes simplex virus type 2 (HSV-2) glycoprotein D (gD2) gene was inserted into an intergenic site in the unique short region of the Oka VZV genome. Expression of gD2 in cells infected with the recombinant Oka strain VZV (ROka-gD2) was confirmed by antibody staining of fixed cells and by immunoblot analysis. Forty days after the third inoculation, guinea pigs were challenged intravaginally with HSV-2. Inoculation of guinea pigs with ROka-gD2 significantly reduced the severity of primary HSV-2 infection (P < 0.001) [PubMed: 7494331]." ; rdfs:label "US6 from Herpes simplex virus type 1 and 2" ; rdfs:seeAlso "Protegen ID: 499; NCBI Gene GI: 1487358; NCBI Protein GI: 9629336; NCBI Protein Accession: NP_044536; NCBITaxon: 10310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011097 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The present study evaluated the modulatory functions of salbutamol co-administered with DNA vaccine expressing gB (UL27) of herpes simplex virus (HSV) via intranasal (i.n.) route. The enhanced immune responses caused by co-administration of salbutamol provided effective and rapid responses to HSV mucosal challenge, thereby conferring prolonged survival and reduced inflammation against viral infection [PubMed: 19641376]." ; rdfs:label "UL27 from Herpes simplex virus type 2" ; rdfs:seeAlso "Protegen ID: 500; NCBI Protein GI: 1869850; NCBITaxon: 10310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011098 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice receiving a glycoprotein D1 (gD1, US5) DNA vaccine alone were 80% protected against a subsequent HSV-1 challenge. Results also indicate that the administration of NLX as an adjuvant improved protective immunity against HSV-1 [PubMed: 19174474]." ; rdfs:label "US5" ; rdfs:seeAlso "Protegen ID: 501; NCBI Gene GI: 2703406; NCBI Protein GI: 9629447; NCBI Protein Accession: NP_044668; NCBITaxon: 10298" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011099 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study demonstrated that recombinant Listeria monocytogenes (Lm) expressing the H-2K(b) glycoprotein B (gB, UL27)(498-505) peptide from HSV-1 triggers a robust CD8 T cell response to this Ag resulting in protective immunity to HSV infection in mice [PubMed: 17404252]." ; rdfs:label "UL27 from Herpes simplex virus type 1" ; rdfs:seeAlso "Protegen ID: 502; NCBI Gene GI: 2703455; NCBI Protein GI: 9629408; NCBI Protein Accession: NP_044629; NCBITaxon: 10298" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011100 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Particle-mediated DNA vaccination of mice with a DNA plasmid-encoding ICP27 resulted in the induction of ICP27-specific IFN-gamma and TNF-alpha production in Balb/c mice. When the DNA vaccine was supplemented with as little as 50ng of a vector encoding the A and B subunits of the Escherichia coli heat labile enterotoxin (LT), animals were profoundly protected from morbidity and mortality [PubMed: 16621198]." ; rdfs:label "ICP27 from Herpes simplex virus type 2" ; rdfs:seeAlso "Protegen ID: 503; NCBI Protein GI: 124181; NCBITaxon: 10315" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011101 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Epitopes from the ICP27 (H1, H2), glycoprotein B (gB) and glycoprotein D (gD) proteins of HSV-1 were attached to either the J TCBL/ICBL or the G TCBL/ICBL. The JH1, JH2, JgB and JgD vaccines elicited DTH responses without antibody but conferred protection upon lethal challenge with HSV [PubMed: 15569635]." ; rdfs:label "ICP27 from Herpes simplex virus type 1" ; rdfs:seeAlso "Protegen ID: 504; NCBI Protein GI: 75812153; NCBITaxon: 10298" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011102 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In two experiments, mice immunised with phage displaying a single epitope of gG2 (US4) were protected against challenge with a lethal dose of whole HSV-2 [PubMed: 10725197]." ; rdfs:label "US4" ; rdfs:seeAlso "Protegen ID: 505; NCBI Gene GI: 1487356; NCBI Protein GI: 9629334; NCBI Protein Accession: NP_044534; NCBITaxon: 10310" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011103 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protection against a lethal intraperitoneal challenge of HSV-1 (5 x 10(4) pfu) with gC (UL44) or gE plasmid vaccination could be demonstrated if the inoculating dose of DNA was 250 microg. All mice immunized with vaccinia recombinants expressing either gC or gE survived HSV-1 challenge [PubMed: 9728527]." ; rdfs:label "UL44 from Herpes simplex virus type 1 and 2" ; rdfs:seeAlso "Protegen ID: 506; NCBI Gene GI: 2703410; NCBI Protein GI: 9629425; NCBI Protein Accession: NP_044646; NCBITaxon: 10298" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011104 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protection against a lethal intraperitoneal challenge of HSV-1 (5 x 10(4) pfu) with gC or gE (US8) plasmid vaccination could be demonstrated if the inoculating dose of DNA was 250 microg. All mice immunized with vaccinia recombinants expressing either gC or gE survived HSV-1 challenge [PubMed: 9728527]." ; rdfs:label "US8" ; rdfs:seeAlso "Protegen ID: 507; NCBI Gene GI: 2703448; NCBI Protein GI: 9629449; NCBI Protein Accession: NP_044670; NCBITaxon: 10298" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010834, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011105 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "E7" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers combined the HPV16 E7 peptide(38-61) with a murine IgG heavy chain constant region to construct a chimeric protein compound. The chimeric vaccine candidate was able to effectively protect mice against the challenge of HPV16-positive tumor cells, and to eradicate HPV16-expressing tumors in mice [PubMed: 15661238]." ; rdfs:label "HPV E7" ; rdfs:seeAlso "Protegen ID: 509; NCBI Gene GI: 1489079; NCBI Protein GI: 9627105; NCBI Protein Accession: NP_041326; NCBITaxon: 333760" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010786, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011106 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "L2" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Antibody responses of mice (n = 120) and rabbits (n = 23) to vaccination with HPV-16 amino-terminal L2 polypeptides or multitype L2 fusion proteins were compared. 11-200 x 3 formulated in GPI-0100 adjuvant or alum with 1018 ISS protected mice against HPV-16 challenge (reduction in HPV-16 infection vs phosphate-buffered saline control, P < .001) 4 months after vaccination as well as HPV-16 L1 VLPs [PubMed: 19470949]." ; rdfs:label "HPV L2" ; rdfs:seeAlso "Protegen ID: 510; NCBI Gene GI: 1489081; NCBI Protein GI: 9627107; NCBI Protein Accession: NP_041331; NCBITaxon: 333760" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010786, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011107 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "E6" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "C57BL/6 mice vaccinated with pNGVL4a-E6/opt are able to generate potent protective and therapeutic antitumor effects against challenge with E6-expressing tumor cell line, TC-1 of HPV [PubMed: 16649071]." ; rdfs:label "HPV E6" ; rdfs:seeAlso "Protegen ID: 511; NCBI Gene GI: 1489078; NCBI Protein GI: 9627104; NCBI Protein Accession: NP_041325; NCBITaxon: 333760" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010786, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011108 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "L1" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "rAAV5, -8 and -9 vectors expressing an HPV16 L1/E7 fusion gene were generated and applied intranasally for combined prophylactic and therapeutic vaccination of mice. Vaccination with the rAAV vectors led to a significant protection of animals against a challenge with different HPV tumour cell lines [PubMed: 20032542]." ; rdfs:label "HPV L1" ; rdfs:seeAlso "Protegen ID: 512; NCBI Gene GI: 1489082; NCBI Protein GI: 9627108; NCBI Protein Accession: NP_041332; NCBITaxon: 333760" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010786, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011109 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The DNA vaccine pIHNw-G encodes the glycoprotein of the fish rhabdovirus infectious hematopoietic necrosis virus (IHNV). Vaccine performance in rainbow trout was measured 3, 6, 13, 24, and 25 months after vaccination. At three months all fish vaccinated with 0.1 microg pIHNw-G had detectable neutralizing antibody (NAb) and they were completely protected from lethal IHNV challenge with a relative percent survival (RPS) of 100% compared to control fish [PubMed: 16154239]." ; rdfs:label "G glycoprotein from Infectious Hematopoietic Necrosis Virus" ; rdfs:seeAlso "Protegen ID: 513; NCBI Gene GI: 1489848; NCBI Protein GI: 9628086; NCBI Protein Accession: NP_042679; NCBITaxon: 11290" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010810, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011110 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized intranasally with an adjuvant (cholera toxin B subunit containing 0.2% of the whole toxin)-combined with A or B virus recombinant NP. The NP-immune mice, when challenged intranasally with a sublethal dose of the virus 3 wk after immunization, had accelerated virus clearance from the nasal site in both an influenza type-specific and a nonspecific manner, as shown by the protection from high morbidity from the second day after challenge [PubMed: 8621928]." ; rdfs:label "NP from Influenza B virus" ; rdfs:seeAlso "Protegen ID: 514; NCBI Gene GI: 956539; NCBI Protein GI: 8486155; NCBI Protein Accession: NP_056661; NCBITaxon: 11520" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011111 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized intranasally with an adjuvant (cholera toxin B subunit containing 0.2% of the whole toxin)-combined with A or B virus recombinant NP. The NP-immune mice, when challenged intranasally with a sublethal dose of the virus 3 wk after immunization, had accelerated virus clearance from the nasal site in both an influenza type-specific and a nonspecific manner, as shown by the protection from high morbidity from the second day after challenge [PubMed: 8621928]." ; rdfs:label "NP from Influenza A virus H3N2" ; rdfs:seeAlso "Protegen ID: 515; NCBI Protein GI: 3722159; NCBITaxon: 41857" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011112 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Skin and mucosal vaccination provided complete protection from clinical signs of infection with ponies subjected to a challenge infection of Equine influenza virus, while skin vaccination provided partial protection; DNA vaccination provided partial protection from viral shedding [PubMed: 10403592]." ; rdfs:label "HA from Equine influenza virus H3N8" ; rdfs:seeAlso "Protegen ID: 516; NCBI Protein GI: 404517; NCBITaxon: 31660" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011113 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A nonpathogenic vector of the cytoplasmic domain of the VSV G protein and expressing influenza virus HA (derived from Influenza A virus (A/WSN/1933(H1N1))) provides complete protection from lethal influenza virus challenge after intranasal administration. A second vector with VSV G deleted and expressing HA (DeltaG-HA) is also protective and nonpathogenic and has the advantage of not inducing neutralizing antibodies to the vector itself [PubMed: 10196265]." ; rdfs:label "HA from Influenza A virus (A/WSN/1933(H1N1))" ; rdfs:seeAlso "Protegen ID: 518; NCBI Protein GI: 324200; NCBITaxon: 382835" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011114 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A recombinant baculovirus expressing the hemagglutinin gene of the influenza virus, A/PR/8/34 (H1N1), under the control of the chicken beta-actin promoter, was constructed. Protection from a lethal challenge of the influenza virus was achieved by intranasal immunization of the recombinant baculovirus [PubMed: 12874198]." ; rdfs:label "HA from Influenza A virus (A/Puerto Rico/8/1934(H1N1))" ; rdfs:seeAlso "Protegen ID: 519; NCBI Protein GI: 126599271; NCBITaxon: 211044" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011115 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Two cyclic peptide analogues corresponding to residues 139-146 (site A) of influenza A virus haemagglutinin (strain X31) were synthesized. When OF1 mice were immunized with cyclic peptides, approximately 80% of the animals were protected against an intranasal challenge with influenza virus [PubMed: 2396470]." ; rdfs:label "HA from Influenza A virus (A/Aichi/2/1968(H3N2)), (X31)" ; rdfs:seeAlso "Protegen ID: 520; NCBI Protein GI: 324132; NCBITaxon: 387139" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011116 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice and ferrets were immunised with two doses of the split virus vaccine (12-24 microg haemagglutinin derived from Influenza A virus (A/chicken/Italy/13474/99(H7N1))) with or without aluminium hydroxide adjuvant and challenged 3 weeks after second dose with the highly pathogenic A/chicken/Italy/13474/99 (H7N1) virus. The vaccine induced significant protection from disease after challenge with the wild-type virus. In the murine lethal challenge model, vaccination effectively prevented death and, furthermore, formulation with adjuvant reduced excessive weight loss and viral shedding [PubMed: 19453487]." ; rdfs:label "HA from Influenza A virus (A/chicken/Italy/13474/99(H7N1))" ; rdfs:seeAlso "Protegen ID: 521; NCBI Protein GI: 32261025; NCBITaxon: 199442" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011117 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization and challenge experiments in mice indicated that even though vaccination with the recombinant HA vaccinia viruses derived from Influenza B virus (Strain B/England/222/82) induced different levels of cross-reactive neutralizing antibodies, mice vaccinated with either recombinant vaccinia virus were protected from infection with either subpopulation of influenza virus [PubMed: 3318092]." ; rdfs:label "HA from Influenza B virus (Strain B/England/222/82)" ; rdfs:seeAlso "Protegen ID: 522; NCBI Protein GI: 122955; NCBITaxon: 11527" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011118 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated with a recombinant VLP vaccine from both influenza A H5N1 clade 1 and clade 2 isolates (Influenza A virus (A/duck/Badung-Bali/05/2005(H5N1))) with pandemic potential were protected against challenge with lethal reassortant viruses expressing the H5N1 HA and NA, regardless if the H5N1 clade was homologous or heterologous to the vaccine [PubMed: 18231588]." ; rdfs:label "HA from Influenza A virus (A/duck/Badung-Bali/05/2005(H5N1))" ; rdfs:seeAlso "Protegen ID: 523; NCBI Protein GI: 190344179; NCBITaxon: 389226" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011119 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A targeted fusion protein based on the CTA1-DD adjuvant and containing tandem repeats of the matrix protein 2 (M2e) ectodomain epitope derived from Influenza A virus (A/Puerto Rico/8/34(H1N1)), CTA1-3M2e-DD, confers strong protective immunity against a potentially lethal challenge infection with influenza virus in mice. The formulation was highly effective for mucosal immunizations and promoted high M2e-specific serum IgG and mucosal IgA antibody titers and an hitherto unknown anti-M2e CD4 T cell immunity [PubMed: 18243429]." ; rdfs:label "M2 from Influenza A virus (A/Puerto Rico/8/34(H1N1))" ; rdfs:seeAlso "Protegen ID: 524; NCBI Gene GI: 956528; NCBI Protein GI: 56583270; NCBI Protein Accession: NP_040979; NCBITaxon: 211044" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011120 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination with HA-VRP derived from Influenza A virus (A/Hong Kong/1/68(H3N2)) did not strongly stimulate either neutralizing or IgG1 antibodies but did induce IgG2a antibodies. Expression of IgG2a antibodies in this context correlated with clearance of virus and increased protection against lethal influenza challenge [PubMed: 16960108]." ; rdfs:label "HA from Influenza A virus (A/Hong Kong/1/68(H3N2))" ; rdfs:seeAlso "Protegen ID: 525; NCBI Protein GI: 16960108; NCBITaxon: 10090" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011121 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers report that a DNA vaccine encoding hemagglutinin from the index human influenza isolate A/HK/156/97 provides immunity against H5N1 infection of mice [PubMed: 9971791]." ; rdfs:label "HA from Influenza A virus (A/environment/Hong Kong/156/1997(H5N1))" ; rdfs:seeAlso "Protegen ID: 527; NCBI Protein GI: 269826115; NCBITaxon: 680785" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011122 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A simian adenovirus 24 (AdC7) vector expressing the influenza A/Puerto Rico/8/34 NP was tested for its efficacy in protecting BALB/c mice against two H5N1 strains. When tested in a mouse challenge model, there was a significantly improved survival rate following challenge with the Vietnam/1203/04 strain of H5N1 that has caused human outbreaks [PubMed: 17728024]." ; rdfs:label "NP from Influenza A virus (A/Puerto Rico/8/34(H1N1))" ; rdfs:seeAlso "Protegen ID: 528; NCBI Gene GI: 956531; NCBI Protein GI: 8486130; NCBI Protein Accession: NP_040982; NCBITaxon: 211044" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011123 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The protective effect of neuraminidase (NA) was studied in a mouse protection test using isolated neuraminidase of A2/Aichi/68(H3N2) virus and the complete recombinant virus A/eq(Heq-1)-HK(N2) as antigens. Immunized mice were protected against A2/Aichi(H3N2) challenge virus; however, the protection rate was low in comparison to animals immunized with comparable amounts of the complete A2/68(H3N2) virus9 [PubMed: 1126575]." ; rdfs:label "NA from Influenza A virus (A/Aichi/2/1968(H3N2))" ; rdfs:seeAlso "Protegen ID: 530; NCBI Protein GI: 46401580; NCBITaxon: 387139" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011124 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In mouse models of influenza infection, the vaccines derived from Influenza A virus (A/Solomon Islands/3/2006(H1N1)) hemagglutinin elicit robust antibody responses that mitigate disease and protect mice from lethal challenge [PubMed: 18493310]." ; rdfs:label "HA from Influenza A virus (A/Solomon Islands/3/2006(H1N1))" ; rdfs:seeAlso "Protegen ID: 531; NCBI Protein GI: 156123416; NCBITaxon: 464623" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011125 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Results indicated that two doses of 10 microg of pCAGGoptiHA derived from Influenza A virus (A/Goose/Guangdong/1/96(H5N1)) could induce complete protection in chickens against H5 lethal virus challenge [PubMed: 17451817]." ; rdfs:label "HA from Influenza A virus (A/Goose/Guangdong/1/96(H5N1))" ; rdfs:seeAlso "Protegen ID: 532; NCBI Gene GI: 3654620; NCBI Protein GI: 73852955; NCBI Protein Accession: YP_308669; NCBITaxon: 93838" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011126 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The inoculation of HA vaccine prepared from influenza viruses A/Yamagata/120/86 (H1N1) or A/Fukuoka/C29/85 (H3N2) together with CTB provided partial protection against PR-8 infection in Balb/c mice [PubMed: 2781859]." ; rdfs:label "HA from Influenza A virus (A/Yamagata/120/1986(H1N1))" ; rdfs:seeAlso "Protegen ID: 533; NCBI Protein GI: 221344; NCBITaxon: 379740" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011127 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The inoculation of HA vaccine prepared from influenza viruses A/Yamagata/120/86 (H1N1) or A/Fukuoka/C29/85 (H3N2) together with CTB provided partial protection against PR-8 infection in Balb/c mice [PubMed: 2781859]." ; rdfs:label "HA from Influenza A virus (A/Fukuoka/C29/85(H3N2))" ; rdfs:seeAlso "Protegen ID: 534; NCBI Protein GI: 221306; NCBITaxon: 62549" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011128 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protection against a lethal influenza B virus infection was examined in BALB/c mice immunized with plasmid DNAs encoding hemagglutinin (HA), neuraminidase (NA and NB) and nucleoprotein (NP) from the B/Ibaraki/2/85 virus. Both HA and NA DNAs conferred complete protection against the lethal challenge in all the tested mouse strains [PubMed: 11163667]." ; rdfs:label "HA from Influenza B virus (B/Ibaraki/2/85)" ; rdfs:seeAlso "Protegen ID: 535; NCBI Protein GI: 122959; NCBITaxon: 107411" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011129 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protection against a lethal influenza B virus infection was examined in BALB/c mice immunized with plasmid DNAs encoding hemagglutinin (HA), neuraminidase (NA and NB) and nucleoprotein (NP) from the B/Ibaraki/2/85 virus. Both HA and NA DNAs conferred complete protection against the lethal challenge in all the tested mouse strains [PubMed: 11163667]." ; rdfs:label "NA from Influenza B virus (B/Ibaraki/2/85)" ; rdfs:seeAlso "Protegen ID: 536; NCBI Protein GI: 53829726; NCBITaxon: 107411" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011130 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Viral challenge studies showed that live BacHA derived from Influenza A virus (A/Indonesia/CDC669/2006(H5N1)) was able to provide 100% protection against 5 50% mouse lethal doses (MLD(50)) of homologous (clade 2.1) and heterologous (clade 1) H5N1 [PubMed: 20071572]." ; rdfs:label "HA from Influenza A virus (A/Indonesia/CDC669/2006(H5N1))" ; rdfs:seeAlso "Protegen ID: 537; NCBI Protein GI: 113497156; NCBITaxon: 400828" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011131 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Viral challenge studies showed that live BacHA derived from Influenza A virus (A/Indonesia/CDC594/2006(H5N1)) was able to provide 100% protection against 5 50% mouse lethal doses (MLD(50)) of homologous (clade 2.1) and heterologous (clade 1) H5N1 [PubMed: 20071572]." ; rdfs:label "HA from Influenza A virus (A/Indonesia/CDC594/2006(H5N1))" ; rdfs:seeAlso "Protegen ID: 538; NCBI Protein GI: 113495780; NCBITaxon: 400810" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011132 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A DNA vaccine encoding HA (from Influenza A virus (A/Hawaii/01/1991(H3N2))), NP and M1 (from a 1989 strain) protected ferrets better against challenge with the antigenic drift variant A/Georgia/03/93 than did the inactivated vaccine from the 1992-93 influenza season. Researchers report that the same DNA vaccine protected ferrets against a second, further divergent, drift variant (A/Johannesburg/33/94) [PubMed: 9234535]." ; rdfs:label "HA from Influenza A virus (A/Hawaii/01/1991(H3N2))" ; rdfs:seeAlso "Protegen ID: 539; NCBI Protein GI: 110313990; NCBITaxon: 387158" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011133 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with HA plasmid once and the NA plasmid twice survived 100% [PubMed: 19067149]." ; rdfs:label "HA from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ; rdfs:seeAlso "Protegen ID: 540; NCBI Protein GI: 61698018; NCBITaxon: 319102" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011134 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with NP plasmid showed 60-80% survival rate with at least three immunizations. The mixture of M1 and NP plasmids protected 95% of the mice against the homologous virus, and 80% of the mice against a challenge with heterologous H1N1 (PR8) virus [PubMed: 19067149]." ; rdfs:label "NP from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ; rdfs:seeAlso "Protegen ID: 541; NCBI Protein GI: 61698066; NCBITaxon: 319102" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011135 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with HA plasmid once and the NA plasmid twice survived 100% [PubMed: 19067149]." ; rdfs:label "NA from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ; rdfs:seeAlso "Protegen ID: 542; NCBI Protein GI: 61698053; NCBITaxon: 319102" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011136 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Plasmids carrying the HA, NA, NP, M1, and M2 genes, respectively, of the avian influenza virus (AIV) A/Chicken/Henan/12/2004(H5N1) strain were administered to mice, and the mice were challenged with the homologous virus later. The mice immunized with M1 plasmid survived 25% with five immunizations. The mixture of M1 and NP plasmids protected 95% of the mice against the homologous virus, and 80% of the mice against a challenge with heterologous H1N1 (PR8) virus [PubMed: 19067149]." ; rdfs:label "M1 from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ; rdfs:seeAlso "Protegen ID: 543; NCBI Protein GI: 61698034; NCBITaxon: 319102" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011137 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination with ptPAs/NP derived from Influenza A virus (A/chicken/Hubei/489/2004(H5N1)) efficiently cleared the homologous H5N1 influenza virus in the infected lungs and induced partial cross-protection against heterologous, highly pathogenic H5N1 strains in mice [PubMed: 18789973]." ; rdfs:label "NP from Influenza A virus (A/chicken/Hubei/489/2004(H5N1))" ; rdfs:seeAlso "Protegen ID: 544; NCBI Protein GI: 55233233; NCBITaxon: 298603" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011138 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers evaluated the immunogenicity and efficacy of a panel of flagellin-based hemagglutinin (HA) globular head fusion vaccines in inbred mice. The HA globular head of these vaccines was derived from the A/Vietnam/1203/04 (VN04; H5N1) HA molecule. Results show that replacement of domain D3 of flagellin with the VN04 HA globular head creates a highly effective vaccine that elicits protective HAI titers which protect mice against disease and death in a lethal challenge model with H5 VN virus [PubMed: 19654064]." ; rdfs:label "HA from Influenza A virus (A/Viet Nam/1203/2004(H5N1))" ; rdfs:seeAlso "Protegen ID: 545; NCBI Protein GI: 159144921; NCBITaxon: 284218" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011139 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Using reverse genetics, we constructed a recombinant NDV expressing an H9 AIV hemagglutinin (HA) from an H9N2 field isolate, A/Chicken/ Shandong/2/2007. When tested, 90% of chickens were protected from clinical disease, mortality, and virus shedding against challenge with homologous H9N2 AIV [PubMed: 20521648]." ; rdfs:label "HA from Influenza A virus (A/chicken/Guangdong/02/2007(H9N2))" ; rdfs:seeAlso "Protegen ID: 546; NCBI Protein GI: 206812650; NCBITaxon: 563925" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011140 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with DNA/rAd5 vaccines encoding HA derived from Influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1)) conferred protection in ferrets against a stringent virus challenge [PubMed: 20352112]." ; rdfs:label "HA from Influenza A virus (A/Thailand/1(KAN-1)/2004(H5N1))" ; rdfs:seeAlso "Protegen ID: 547; NCBI Nucleotide GI: 46578137; NCBI Protein GI: 46578138; NCBI Protein Accession: AAS65615.2; NCBITaxon: 266827" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011141 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "All specific-pathogen-free chickens immunized with (vFP89) expressing the native hemagglutinin (HA) gene from H5N8 A/turkey/ Ireland/1378/83 were clinically protected from HPAI challenge [PubMed: 20521642]." ; rdfs:label "HA from Influenza A virus (A/turkey/Ireland/1378/1983(H5N8))" ; rdfs:seeAlso "Protegen ID: 549; NCBI Protein GI: 115279333; NCBITaxon: 380285" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011142 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "All specific-pathogen-free chickens immunized with (vFP2211) expressing a modified synthetic HA gene from H5N1 A/chicken/Indonesia/7/2003 were clinically protected from HPAI challenge [PubMed: 20521642]." ; rdfs:label "HA from Influenza A virus (A/chicken/Indonesia/7/2003(H5N1))" ; rdfs:seeAlso "Protegen ID: 550; NCBI Protein GI: 129282887; NCBITaxon: 430432" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011143 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A neutralizing monoclonal antibody (mAb) 9F4 against the hemagglutinin (HA) of the influenza A/chicken/hatay/2004 H5N1 virus was generated. MAb 9F4 was found to be protective, both prophylactically and therapeutically, against lethal viral challenge of mice [PubMed: 20519402]." ; rdfs:label "HA from Influenza A virus (A/Hatay/2004/(H5N1))" ; rdfs:seeAlso "Protegen ID: 551; NCBI Protein GI: 56311402; NCBITaxon: 303316" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011144 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Chickens immunized with attenuated Salmonella strains expressing the hemagglutinin (HA1) gene from a highly pathogenic avian influenza (HPAI) H5N1 (A/whooper swan/Mongolia/3/2005) demonstrated a statistically significant increase in survival compared to control groups [PubMed: 20406663]." ; rdfs:label "HA from Influenza A virus (A/whooper swan/Mongolia/3/05(H5N1))" ; rdfs:seeAlso "Protegen ID: 553; NCBI Protein GI: 81687119; NCBITaxon: 344596" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011145 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers constructed a recombinant pseudotype baculovirus encoding the JEV envelope (E) protein and demonstrated that it could elicit high protective immunity in mice. Intramuscular injections of BV-G-E at various doses into mice produced higher levels of JEV-specific neutralizing antibodies, IFN-gamma and better protective efficacy against a lethal challenge with JEV than that of pc-E. Furthermore, BV-G-E could elicit a higher level of cellular immunity response and provide equal protective efficacy against JEV challenge compared to inactivated vaccine [PubMed: 19006097]." ; rdfs:label "Envelope protein" ; rdfs:seeAlso "Protegen ID: 554; NCBI Protein GI: 16445023; NCBITaxon: 11072" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010783, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011146 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers established a simple and effective method for DNA immunization against Japanese encephalitis virus (JEV) infection with plasmids encoding the viral PrM and E proteins and colloidal gold. After being inoculated twice, BALB/c mice were found to resist challenge with 100,000 times the 50% lethal dose (LD(50)) of JEV (Beijing-1 strain) even when immunized with a relatively small dose of 0.5 micro g of plasmid DNA [PubMed: 12634382]." ; rdfs:label "PrM from Japanese encephalitis virus" ; rdfs:seeAlso "Protegen ID: 555; NCBI Protein GI: 90019439; NCBITaxon: 11072" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010783, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011147 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Balb/c mice and swine vaccinated with TK(-)/gG(-)/NS1(+) expressing NS1 protein of JEV could confer protective immunity against lethal challenge of the virulent PRV Ea strain and develop a good humoral and cellular immune response against JEV [PubMed: 15121294]." ; rdfs:label "NS1 from Japanese encephalitis virus" ; rdfs:seeAlso "Protegen ID: 556; NCBI Protein GI: 18418672; NCBITaxon: 11072" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010783, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011148 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers constructed plasmid DNAs encoding JE virus proteins. Cytotoxic T lymphocytes (CTLs) were induced by NS3 in a mouse model. Three immunizations with pUJENS3 provided a 50% partial protection from a lethal dose of JE virus [PubMed: 12922097]." ; rdfs:label "NS3" ; rdfs:seeAlso "Protegen ID: 557; NCBI Protein GI: 27696332; NCBITaxon: 11072" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010783, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011149 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers constructed plasmid DNAs encoding JE virus proteins. Cytotoxic T lymphocytes (CTLs) were induced by NS5 in a mouse model. Three immunizations with pUJENS5 provided a 57% partial protection from a lethal dose of JE virus [PubMed: 12922097]." ; rdfs:label "NS5" ; rdfs:seeAlso "Protegen ID: 558; NCBI Protein GI: 158702649; NCBITaxon: 11072" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010783, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011150 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A cDNA clone representing the genome of structural proteins of Japanese encephalitis virus (JEV) was inserted into the thymidine kinase gene of vaccinia virus strains LC16mO and WR. Inoculation of rabbits with the infectious recombinant vaccinia virus resulted in rapid production of antiserum specific for the PreM and E glycoproteins of JEV. Mice vaccinated with the recombinant produced JEV-neutralizing antibodies and were resistant to challenge with JEV [PubMed: 2159544]." ; rdfs:label "PreM" ; rdfs:seeAlso "Protegen ID: 559; NCBI Protein GI: 14600066; NCBITaxon: 11072" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010783, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011151 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccine efficacy trials in guinea pigs indicated that the nucleoprotein is capable of eliciting a protective immune response against a lethal dose of Lassa virus. Ninety-four percent of the animals vaccinated with V-LSN survived a Lassa virus challenge in which only 14% of unvaccinated animals and 39% of animals vaccinated with the New York Board of Health (NYBH) strain of vaccinia virus survived [PubMed: 2741340]." ; rdfs:label "LASVsSgp1 nucleoprotein" ; rdfs:seeAlso "Protegen ID: 560; NCBI Gene GI: 956584; NCBI Protein GI: 23343510; NCBI Protein Accession: NP_694869; NCBITaxon: 11620" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010763, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011152 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized with a vaccine expressing the 78kDa (GRP-78) antigen of Leishmania donovani. Challenge infection was given intracardially after 2 weeks of second booster. A significant decrease in parasite burden was seen in vaccinees over the infected controls on all post challenge days and was found that maximum protection was provided by 78kDa+rIL-12 vaccine. It was highly immunogenic as depicted by the reduction in parasite load (71-94.8%) [PubMed: 20093205]." ; rdfs:label "GRP-78" ; rdfs:seeAlso "Protegen ID: 561; NCBI Protein GI: 16797868; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011153 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study results show that a single intraperitoneal administration of the A2-recombinant L. tarentolae strain expressing the Leishmania donovani A2 antigen protects BALB/c mice against L. infantum challenge and that protective immunity is associated with high levels of IFN-gamma production prior and after challenge [PubMed: 19818721]." ; rdfs:label "A2" ; rdfs:seeAlso "Protegen ID: 563; NCBI Protein GI: 30385439; NCBITaxon: 5671" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011154 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD31 (ATP synthase alpha chain) reduced parasite burden by 74%-77% [PubMed: 19503834]." ; rdfs:label "F1-ATPase" ; rdfs:seeAlso "Protegen ID: 564; NCBI Protein GI: 722242; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011155 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD51 (beta-tubulin) reduced parasite burden by 72%-75% [PubMed: 19503834]." ; rdfs:label "Beta-tubulin" ; rdfs:seeAlso "Protegen ID: 565; NCBI Protein GI: 262233287; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011156 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study compared the vaccine efficacy of various L. donovani antigens encapsulated in cationic liposomes in BALB/c mice against challenge infection with L. donovani. Results demonstrated that liposomal LD72 (Hsp70) reduced parasite burden by 65%-67% [PubMed: 19503834]." ; rdfs:label "Hsp70" ; rdfs:seeAlso "Protegen ID: 566; NCBI Protein GI: 281426606; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011157 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "KMP-11 DNA vaccination alone in an experimental BALB/c mice model showed significant potential in terms of resolution of splenic and hepatic parasite burden against virulent LD challenge. KMP-11 DNA immunization significantly protects against L. donovani infection [PubMed: 19162111]." ; rdfs:label "KMP-11" ; rdfs:seeAlso "Protegen ID: 567; NCBI Protein GI: 7579896; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011158 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study showed that cationic distearoyl phosphatidylcholine (DSPC) liposomes, when used as vaccine adjuvant with the immunodominant 63-kDa glycoprotein (gp63, mspC) of Leishmania donovani promastigotes, induced significant protection against progressive visceral leishmaniasis in susceptible BALB/c mice. gp63 used without adjuvant elicited partial protection but in association with liposomes exhibited marked resistance in both the livers and spleens of the mice challenged 10 days after the last vaccination [PubMed: 18195029]." ; rdfs:label "MspC" ; rdfs:seeAlso "Protegen ID: 568; NCBI Protein GI: 21954466; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011159 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "An expression plasmid encoding both p35 and p40 subunits of IL-12 when co-administered with a recombinant open-reading frame (rORFF) gene from the LD1 locus of Leishmania donovani induces significant protection with around 82% protection in both liver and spleen of BALB/c mice when challenged with L. donovani [PubMed: 16413950]." ; rdfs:label "ORFF" ; rdfs:seeAlso "Protegen ID: 569; NCBI Protein GI: 703122; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011160 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization of mice with recombinant BT1 proteins (a biopterin transporter) from multigenic LD1 locus on chromosome 35 of L. donovani conferred partial protection against challenge with Leishmania donovani in a BALB/c mice [PubMed: 15357215]." ; rdfs:label "BT1" ; rdfs:seeAlso "Protegen ID: 570; NCBI Protein GI: 703123; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011161 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Experimental infection of immunized BALB/c mice demonstrated that the VR1012-NH36 DNA vaccine derived from the nucleoside hydrolase gene (NH) of L. donovani induced an 88% reduction in L. chagasi parasite load and a 65% reduction in L. mexicana lesion size [PubMed: 15664920]." ; rdfs:label "NH" ; rdfs:seeAlso "Protegen ID: 571; NCBI Protein GI: 19697561; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011162 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study demonstrated for the first time that a recombinant stage-specific hydrophilic surface protein of Leishmania donovani, recombinant hydrophilic acylated surface protein B1 (HASPB1), is able to confer protection against experimental challenge with L. donovani in BALB/c mice [PubMed: 11120835]." ; rdfs:label "L. donovani HASPB1" ; rdfs:seeAlso "Protegen ID: 572; NCBI Protein GI: 51847753; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010832, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011163 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Nonhuman primates (cynomolgus macaques) were inoculated with VEE replicons expressing MBGV GP and/or NP and challenged with MGBV. MBGV NP afforded incomplete (partial) protection, sufficient to prevent death but not disease in two of three macaques [PubMed: 9813200 ]." ; rdfs:label "NP from Lake Victoria marburgvirus" ; rdfs:seeAlso "Protegen ID: 573; NCBI Protein GI: 332181; NCBITaxon: 11269" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010769, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011164 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant fowl poxviruses (rFPVs) were constructed to express genes from serotype 1 Marek's disease virus (MDV, Gallid herpesvirus 2). rFPV/gB1 expressing MDV040 conferred 42% protection in maternal antibody-positive chickens when challenged with highly virulent MDV isolates [PubMed: 14562881]." ; rdfs:label "MDV040" ; rdfs:seeAlso "Protegen ID: 574; NCBI Gene GI: 4811501; NCBI Protein GI: 125745079; NCBI Protein Accession: YP_001033956; NCBITaxon: 10390" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010804, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011165 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant fowl poxviruses (rFPVs) were constructed to express genes from serotype 1 Marek's disease virus (MDV, Gallid herpesvirus 2). rFPV/gI expressing MDV095 conferred 43% protection in maternal antibody-positive chickens when challenged with highly virulent MDV isolates [PubMed: 14562881]." ; rdfs:label "MDV095" ; rdfs:seeAlso "Protegen ID: 575; NCBI Gene GI: 4811454; NCBI Protein GI: 125745128; NCBI Protein Accession: YP_001034012; NCBITaxon: 10390" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010804, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011166 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Chimeric Venezuelan equine encephalitis/Sindbis virus (VEE/SIN) replicon particles were used to express the hemagglutinin (H) and fusion (F) proteins of measles virus (MV). When challenged with wild-type MV 12 to 17 months after vaccination, all vaccinated juvenile and infant monkeys vaccinated with VEE/SIN-H, VEE/SIN-H+F, and LAV were protected from rash and viremia [PubMed: 20130066]." ; rdfs:label "H hemagglutinin protein" ; rdfs:seeAlso "Protegen ID: 577; NCBI Gene GI: 1489801; NCBI Protein GI: 9626951; NCBI Protein Accession: NP_056923; NCBITaxon: 11234" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010784, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011167 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated with a vaccinia virus recombinant encoding the fusion protein of Measles virus developed measles neutralizing antibodies. The mice also resisted a normally lethal intracerebral inoculation of a cell-associated measles virus subacute sclerosing panencephalitis strain [PubMed: 3422488]." ; rdfs:label "F fusion protein from Measles virus" ; rdfs:seeAlso "Protegen ID: 578; NCBI Gene GI: 1489800; NCBI Protein GI: 9626950; NCBI Protein Accession: NP_056922; NCBITaxon: 11234" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010784, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011168 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVN (Nucleocapsid Protein) -immunized rats survived a MV challenge infection [PubMed: 1833505]." ; rdfs:label "N nucleocapsid protein" ; rdfs:seeAlso "Protegen ID: 579; NCBI Gene GI: 1489804; NCBI Protein GI: 9626946; NCBI Protein Accession: NP_056918; NCBITaxon: 11234" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010784, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011169 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVP (Phosphoprotein) -immunized rats were partially protected from MV challenge [PubMed: 1833505]." ; rdfs:label "P phosphoprotein" ; rdfs:seeAlso "Protegen ID: 580; NCBI Gene GI: 1489805; NCBI Protein GI: 9626947; NCBI Protein Accession: NP_056919; NCBITaxon: 11234" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010784, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011170 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Lewis rats were immunized with recombinant vaccinia virus (VV) expressing various proteins of measles virus (MV). VVM (Matrix Protein) -immunized rats were partially protected from MV challenge [PubMed: 1833505]." ; rdfs:label "M matrix protein" ; rdfs:seeAlso "Protegen ID: 581; NCBI Gene GI: 1489803; NCBI Protein GI: 9626949; NCBI Protein Accession: NP_056921; NCBITaxon: 11234" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010784, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011171 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A novel mumps vaccine with good immunity and safety was developed by selecting an antigen (HN) component of the mumps virus. The clinical and pathological observations after challenge of vaccinated rhesus monkeys indicated further that the immune response induced by this vaccine provided complete protection from wild-type virus infection [PubMed: 18597904]." ; rdfs:label "HN" ; rdfs:seeAlso "Protegen ID: 582; NCBI Gene GI: 1489765; NCBI Protein GI: 9695422; NCBI Protein Accession: NP_054713; NCBITaxon: 11161" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010785, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011172 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with DNA encoding Ag85B (fbpB), a candidate vaccine antigen of Mycobacterium tuberculosis, elicited in mice a low but protective CD4(+) T cell-mediated IFN-gamma response [PubMed: 20544034]." ; rdfs:label "FbpB from M. tuberculosis" ; rdfs:seeAlso "Protegen ID: 583; NCBI Gene GI: 885785; NCBI Protein GI: 15609023; NCBI Protein Accession: NP_216402; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011173 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Our lead construct, Mtb72F, codes for a 72-kDa polyprotein genetically linked in tandem in the linear order Mtb32(C)-Mtb39-Mtb32(N). All forms of Mtb72F immunization tested resulted in the protection of C57BL/6 mice against aerosol challenge with a virulent strain of M. tuberculosis [PubMed: 15187142]." ; rdfs:label "Mtb72F" ; rdfs:seeAlso "Protegen ID: 584; NCBI Protein GI: 283801990; NCBITaxon: 32630" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011174 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protective experiments of DNA vaccine pcDNA3-MIC3 (pMIC3i) in Kumming mice showed that the vaccine could significantly prolong the survival time of the mice challenged by virulent RH strains of T. gondii [PubMed: 19800170]." ; rdfs:label "MIC3" ; rdfs:seeAlso "Protegen ID: 587; NCBI Gene GI: 7901253; NCBI Protein GI: 237841071; NCBI Protein Accession: XP_002369833; NCBITaxon: 508771" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0011175 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "We show that the 50- to 55-kDa Apa protein, specified by the Rv1860 gene of M. tuberculosis, can elicit both lymphoproliferative response and gamma interferon (IFN-gamma) production. A poxvirus recombinant expressing the Apa protein conferred a significant level of protective immunity in guinea pigs against a challenge dose of virulent M. tuberculosis [PubMed: 12654810]." ; rdfs:label "Apa" ; rdfs:seeAlso "Protegen ID: 588; NCBI Gene GI: 885896; NCBI Protein GI: 57116926; NCBI Protein Accession: YP_177849; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011176 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "MPT63 (Rv1926c), a major secreted protein of Mycobacterium tuberculosis, is immunoreactive in antibody assays in humans and animals and provides protection as a combined DNA vaccine in mice [PubMed: 19281533]." ; rdfs:label "Mpt63" ; rdfs:seeAlso "Protegen ID: 589; NCBI Gene GI: 885334; NCBI Protein GI: 15609063; NCBI Protein Accession: NP_216442; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011177 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The immunogenicity and protective efficacy of a recombinant subunit West Nile virus (WNV) vaccine was evaluated in rhesus macaques (Macaca mulatta). The vaccine consisted of a recombinant envelope (E) protein truncated at the C-terminal end, resulting in a polypeptide containing 80% of the N-terminal amino acids of the native WNV protein (WN-80E), mixed with an adjuvant (GPI-0100). Groups of monkeys were immunized with the WN-80E/GPI-0100 vaccine or an adjuvant-only control formulation. Animals were then challenged by inoculation of wild-type WNV, and the level of viremia in each animal was monitored daily for 10 days. The results showed that whereas all animals in the control group had detectable viremia for at least 3 days after challenge, all of the vaccinated animals were negative on all days after challenge. Thus, the WN-80E vaccine was 100% efficacious in protecting monkeys against infection with WNV [PubMed: 19641099]." ; rdfs:label "E protein from West Nile virus" ; rdfs:seeAlso "Protegen ID: 590; NCBI Protein GI: 111145461; NCBITaxon: 11082" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010803, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011178 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "An antiserum raised in chicken against the TM-1 polypeptide, which was produced by recombinant Escherichia coli cells and purified by column chromatography, inhibited growth of M.g. cells in vitro. Moreover, chickens immunized with this 29 kDa polypeptide (TM-1) were partially protected from a challenge with virulent M.g [PubMed: 8212828]." ; rdfs:label "TM-1" ; rdfs:seeAlso "Protegen ID: 591; NCBI Protein GI: 7249262; NCBITaxon: 2096" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010819, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011179 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Starting with a previously designed eukaryotic expression vector, a recombinant plasmid (pCBWN) that expressed the WN virus prM and E proteins was constructed. A single intramuscular injection of pCBWN DNA induced protective immunity, preventing WN virus infection in mice and horses when subjected to challenge with the NY99-6480 strain of WNV [PubMed: 11287553]." ; rdfs:label "PrM from West Nile virus" ; rdfs:seeAlso "Protegen ID: 592; NCBI Gene GI: 5714902; NCBI Protein GI: 158516888; NCBI Protein Accession: YP_001527877; NCBITaxon: 11082" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010803, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011180 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Seventeen monoclonal antibodies to one of three main cell surface antigens of Neisseria meningitidis group B were tested for protective efficacy in the infant rat using as challenge seven strains of different class 2/3 protein serotypes. Survival of the animals was regularly obtained with antibodies to the P1 protein and to LPS [PubMed: 2510417]." ; rdfs:label "P1 from Neisseria meningitidis" ; rdfs:seeAlso "Protegen ID: 594; NCBI Gene GI: 902192; NCBI Protein GI: 15676020; NCBI Protein Accession: NP_273150; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011181 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Sera of the challenge group immunized with CCPS-P64kR showed a three-fold higher bactericidal response than the sera of the group immunized with the plain CCPS and they were able to protect against challenge with Neisseria meningococci in the infant rat protection model [PubMed: 15039094]." ; rdfs:label "LpdA" ; rdfs:seeAlso "Protegen ID: 596; NCBI Protein GI: 1017430; NCBITaxon: 487" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011182 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with purified Tbp2 survived a lethal challenge to a similar degree as animals immunized with the Tbp1-Tbp2 complex, demonstrating that Tbp2 played an important role in the protective activity observed with the complex, eliciting antibodies that are not only bactericidal but also inhibitory for meningococcal growth [PubMed: 7868259]." ; rdfs:label "TBP2" ; rdfs:seeAlso "Protegen ID: 597; NCBI Protein GI: 1017433; NCBITaxon: 487" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011183 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with recombinant forms of a sporozoite surface antigen (r-p67), derived from either bacterial or insect cells, induces high levels of sporozoite neutralizing antibodies in cattle.In vivo immunization studies have shown that approximately 30% of immunized cattle are nonreactors to a needle LD70 sporozoite challenge, 40% experience a mild disease reaction from which they recover, and the remaining 30% suffer severe disease and are clinically indistinguishable from controls. Transient parasitosis and mild clinical reactions are also observed in challenge of cattle immunized by infection and treatment and such responses constitute immunity to ECF. Hence, p67 is able to routinely induce immunity at a level of about 70% [PubMed: 11193661]." ; rdfs:label "P67" ; rdfs:seeAlso "Protegen ID: 598; NCBI Protein GI: 4106806; NCBITaxon: 5875" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010824, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011184 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "NspA-containing outer membrane vesicles conferred protection against otherwise lethal intraperitoneal challenge of mice with N. meningitidis serogroup B, and sera raised against them mediated opsonophagocytosis of meningococcal strains expressing this antigen [PubMed: 15501782]." ; rdfs:label "NspA from N. meningitidis" ; rdfs:seeAlso "Protegen ID: 599; NCBI Protein GI: 5825543; NCBITaxon: 487" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011185 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A total of 11 meningococcal proteins that are necessary for establishing systemic infection were expressed as recombinant antigens and assessed for their ability to protect mice against live bacterial challenge against N. meningitidis; the lactate permease (LctP) elicited protective immunity [PubMed: 15964482]." ; rdfs:label "LctP" ; rdfs:seeAlso "Protegen ID: 600; NCBI Protein GI: 254667969; NCBITaxon: 662598" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011186 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A total of 11 meningococcal proteins that are necessary for establishing systemic infection were expressed as recombinant antigens and assessed for their ability to protect mice against live bacterial challenge against N. meningitidis; ExbB, which is required for iron acquisition, elicited protective immunity [PubMed: 15964482]." ; rdfs:label "ExbB" ; rdfs:seeAlso "Protegen ID: 601; NCBI Gene GI: 903370; NCBI Protein GI: 15677575; NCBI Protein Accession: NP_274732; NCBITaxon: 122586" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011187 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The trial vaccination of cattle against T. annulata using recombinant sporozoite antigens (SPAG-1 and p67) and/or merozoite antigens (TAMS 1-1 and 1-2). The aim of these trials was to try and enhance the levels of protection induced compared with previous trials. Different approaches were tried. SPAG-1 was expressed as a fusion protein with a His6 tag and then either incorporated into ISCOMs, with or without TAMS 1-1 and 1-2, or administered with RWL, a proprietary saponin-based adjuvant. Cross-protection studies were also performed by immunizing cattle with the T. parva sporozoite antigen, p67, and then challenging with a T. annulata sporozoite stabilate.All the data collected from these two trials indicate that SPAG-1 administered with RWL is better at inducing an effective immune response than SPAG-1 incorporated into ISCOMs, with or without the presence of merozoite antigens [PubMed: 9668470]." ; rdfs:label "Spag-1" ; rdfs:seeAlso "Protegen ID: 602; NCBI Protein GI: 161885; NCBITaxon: 5874" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010825, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011188 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "To test the potential of subunit vaccines against T. annulata infection, we immunized four groups of three calves with either recombinant (re-) (Tams1-1 and Tams1-2) proteins or naked DNA encoding these antigens. All calves vaccinated with ISCOMs proved to be protected from T. annulata infection and had generated antibodies against both re-(Tams1-1 and Tams1-2) at the time of challenge [PubMed: 9364686]." ; rdfs:label "TA17050 merozoite-piroplasm surface antigen Tams1" ; rdfs:seeAlso "Protegen ID: 603; NCBI Gene GI: 3864438; NCBI Protein GI: 84997996; NCBI Protein Accession: XP_953719; NCBITaxon: 353154" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010825, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011189 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intraperitoneal application of NcMAG1 suspended in saponin adjuvants lead to protection against disease in 50% of animals vaccinated in a C57Bl/6 mouse cerebral infection model [PubMed: 19835644]." ; rdfs:label "NcMAG1" ; rdfs:seeAlso "Protegen ID: 604; NCBI Protein GI: 147886433; NCBITaxon: 29176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0011190 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination with an RASV synthesizing full-length PsaA induced high titers of anti-PsaA antibodies in both systemic (IgG in serum) and mucosal (IgA in vaginal washes, nasal washes, and lung homogenates) sites. BALB/c (haplotype H2(d)) or C57BL/6 (haplotype H2(b)) mice vaccinated either orally or intranasally exhibited a significant reduction in colonization of nasopharyngeal tissues after intranasal challenge with S. pneumoniae strains compared to controls, although protection was not observed with all challenge strains. None of the vaccine constructs provided protection against intraperitoneal challenge with S. pneumoniae strain WU2 (serotype 3) [PubMed: 20479086]." ; rdfs:label "PsaA" ; rdfs:seeAlso "Protegen ID: 605; NCBI Protein GI: 209867628; NCBITaxon: 1313" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011191 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A 90% protection rate was achieved following intra-nasal vaccination with recNcPDI emulsified in cholera toxin employing the C57Bl/6 mouse cerebral infection model when challenged with Neospora caninum tachyzoites [PubMed: 19835644]." ; rdfs:label "NcPDI" ; rdfs:seeAlso "Protegen ID: 606; NCBI Protein GI: 82568727; NCBITaxon: 29176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0011192 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The protective effects a pneumolysin mutant (DeltaA146 Ply) against pneumococcal infections in mice was evaluated. Vaccinated mice were challenged with pneumococcal strain D39 at 1,500 times the LD50 (1.5 x 105 CFU) and the vaccinated mice survived significantly longer than control mice after challenge [PubMed: 20038538]." ; rdfs:label "Ply" ; rdfs:seeAlso "Protegen ID: 607; NCBI Gene GI: 4441611; NCBI Protein GI: 116515376; NCBI Protein Accession: YP_817150; NCBITaxon: 373153" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011193 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The protective effects of ATP-dependent caseinolytic protease (ClpP) was evaluated. Vaccinated mice were intraperitoneally and/or intranasally challenged with different pneumococcal strains. In intraperitoneal challenge models with pneumococcal strain D39 (serotype 2), clpP elicited some protection in mice [PubMed: 20038538]." ; rdfs:label "ClpP" ; rdfs:seeAlso "Protegen ID: 608; NCBI Gene GI: 4441476; NCBI Protein GI: 116516216; NCBI Protein Accession: YP_816144; NCBITaxon: 373153" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011194 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The production of a recombinant vaccine was achieved following PCR amplification of putative lipoate protein ligase (Lpl), with subsequent cloning and expression of the genes in E. coli. The putative lipoate protein ligase (Lpl) , resulted in a reduced CFU titre and a trend towards reduced mortality in an animal sepsis model [PubMed: 18034862]." ; rdfs:label "LplA" ; rdfs:seeAlso "Protegen ID: 609; NCBI Gene GI: 934072; NCBI Protein GI: 15903091; NCBI Protein Accession: NP_358641; NCBITaxon: 171101" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011195 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "NcSAG1 and NcSRS2, the two major immunodominant tachyzoite surface antigens of the apicomplexan parasite Neospora caninum, were investigated for their potential as vaccine candidates in mice. Results suggest that a combined DNA/recombinant antigen-vaccine, based on NcSAG1 and NcSRS2, respectively, exhibited a highly significant protective effect against experimentally induced cerebral neosporosis in mice [PubMed: 12741509]." ; rdfs:label "NcSRS2" ; rdfs:seeAlso "Protegen ID: 610; NCBI Protein GI: 5579384; NCBITaxon: 29176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0011196 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "NcSAG1 and NcSRS2, the two major immunodominant tachyzoite surface antigens of the apicomplexan parasite Neospora caninum, were investigated for their potential as vaccine candidates in mice. Results suggest that a combined DNA/recombinant antigen-vaccine, based on NcSAG1 and NcSRS2, respectively, exhibited a highly significant protective effect against experimentally induced cerebral neosporosis in mice [PubMed: 12741509]." ; rdfs:label "NcSAG1" ; rdfs:seeAlso "Protegen ID: 611; NCBI Protein GI: 4583447; NCBITaxon: 29176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0011197 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with recombinant (r)PsrP(BR) had significantly less bacteria in their blood and improved survival versus controls following intranasal challenge [PubMed: 19627498]." ; rdfs:label "PsrP" ; rdfs:seeAlso "Protegen ID: 613; NCBI Gene GI: 7329552; NCBI Protein GI: 221232510; NCBI Protein Accession: YP_002511663; NCBITaxon: 561276" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011198 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """This study used an immunisation/challenge model of transplacental transmission, based on the Qs mouse with an Nc-Liverpool challenge to investigate the vaccine potential of a number of formulations based on four recombinant proteins of N. caninum. A mixture of MIC10 and p24B produced partial protection against transplacental transmission of N. caninum in this mouse model [PubMed: 18789996]. Note: MIC10 must be used in conjunction with p24B in order to confer protection against N. caninum.""" ; rdfs:label "MIC10" ; rdfs:seeAlso "Protegen ID: 614; NCBI Protein GI: 11141617; NCBITaxon: 29176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011199 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intraperitoneal immunization with recombinant SrtA was found to have conferred to mice protection against S. pneumoniae intraperitoneal challenge and the passive transfer of immune serum before intraperitoneal challenge was also protective. Moreover, by using the intranasal challenge model, significant reduction of bacteremia when mice were intraperitoneally immunized with SrtA was observed, while a moderate decrease of lung infection was achieved by intranasal immunization, even though no influence on nasopharynx colonization was seen [PubMed: 19433540]." ; rdfs:label "SrtA" ; rdfs:seeAlso "Protegen ID: 615; NCBI Gene GI: 4442999; NCBI Protein GI: 116515518; NCBI Protein Accession: YP_816547; NCBITaxon: 373153" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011200 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study assessed the potential protectivity of NcMIC1-based vaccination against experimental N. caninum infection in mice. Quantitative real-time PCR revealed that the infection intensity was significantly reduced in the group vaccinated with recNcMIC1 antigen. Serological analysis showed that only recNcMIC1-immunized animals generated detectable antibody levels recognizing native NcMIC1. Thus, of all protocols applied, only recNcMIC1 vaccination appears to be suited to reduce cerebral infection in mice challenged with N. caninum tachyzoites [PubMed: 16108562]." ; rdfs:label "NcMIC1" ; rdfs:seeAlso "Protegen ID: 616; NCBI Protein GI: 17226315; NCBITaxon: 29176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0011201 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Glutamyl tRNA synthetase (GtS) has been found to be among the Streptococcus pneumoniae cell wall-derived proteins that have age-dependent immunogenicity in children. Here, GtS was cloned, expressed, and purified and then was used to immunize 7-week-old BALB/c OlaHsd mice. Thirty-nine percent of rGtS-immunized mice survived a lethal bacterial challenge, whereas no control mice survived [PubMed: 17703427]." ; rdfs:label "GltX" ; rdfs:seeAlso "Protegen ID: 617; NCBI Gene GI: 931970; NCBI Protein GI: 15901888; NCBI Protein Accession: NP_346492; NCBITaxon: 170187" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011202 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Separate groups of gerbils were immunized with purified recombinant proteins singly or in combinations and animals were then challenged with N. caninum. The protective efficacy of each vaccination was determined by assessing animal survival rate. The highest protection efficacy was observed for combined vaccination with NcSRS2 and NcDG1 (67.5% survival) compared to control (17.4% survival). Vaccination with NcDG1 alone elicited 62.5% survival in the challenge model [PubMed: 15793355]." ; rdfs:label "NcDG1" ; rdfs:seeAlso "Protegen ID: 618; NCBI Protein GI: 2149142; NCBITaxon: 29176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0011203 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice were actively immunized with a fragment of choline binding protein A (CbpA; also known as PspC, Hic, and SpsA). CbpA was able to protect mice from intraperitoneal challenge with medium to very high doses of a highly virulent capsular type 2 pneumococcal strain, D39 [PubMed: 11553536]." ; rdfs:label "CbpA" ; rdfs:seeAlso "Protegen ID: 619; NCBI Gene GI: 4441159; NCBI Protein GI: 116515359; NCBI Protein Accession: YP_817402; NCBITaxon: 373153" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011204 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Groups of BALB/c mice immunized with choline binding protein PspA were challenged with either D39 or WCH16. PspA elicited protection by using moderate challenge doses of S. pneumoniae [PubMed: 17088353]." ; rdfs:label "PspA" ; rdfs:seeAlso "Protegen ID: 620; NCBI Gene GI: 4441373; NCBI Protein GI: 116515876; NCBI Protein Accession: YP_815641; NCBITaxon: 373153" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011205 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Separate groups of gerbils were immunized with purified recombinant proteins singly or in combinations and animals were then challenged with N. caninum. The protective efficacy of each vaccination was determined by assessing animal survival rate. All experimental groups showed protective effects. Vaccination with NcDG2 alone elicited 50% survival rate compared to a control survival rate of 17.4% [PubMed: 15793355]." ; rdfs:label "NcDG2" ; rdfs:seeAlso "Protegen ID: 621; NCBI Protein GI: 3237325; NCBITaxon: 29176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000332 ] . obo:VO_0011206 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice were immunized with recombinant 6-Phosphogluconate dehydrogenase (r6PGD) and boosted after 3 weeks. Immunized mice were challenged intranasally with a lethal dose of S. pneumoniae. Immunization of mice with r6PGD protected 60% (P < 0.001) of mice for 5 days and 40% (P < 0.05) of the mice for 21 days following intranasal lethal challenge [PubMed: 16634799]." ; rdfs:label "Gnd" ; rdfs:seeAlso "Protegen ID: 622; NCBI Gene GI: 4441177; NCBI Protein GI: 116515453; NCBI Protein Accession: YP_815856; NCBITaxon: 373153" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011207 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with recombinant PiaA were protected against systemic challenge to a degree similar to those immunized with an existing protein vaccine candidate, PdB (a genetically modified pneumolysin toxoid). Immunization with a combination of both PiuA and PiaA resulted in additive protection and was highly protective against systemic infection with S. pneumoniae [PubMed: 11598041]." ; rdfs:label "PiaA" ; rdfs:seeAlso "Protegen ID: 623; NCBI Gene GI: 4442863; NCBI Protein GI: 116515816; NCBI Protein Accession: YP_815744; NCBITaxon: 373153" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011208 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A recombinant fowlpox virus expressing the fusion protein of Newcastle disease virus strain F48E8 protected chickens against virulent NDV challenge. The protective rate was 96.7% [PubMed: 11191764]." ; rdfs:label "F fusion protein from Newcastle disease virus" ; rdfs:seeAlso "Protegen ID: 624; NCBI Gene GI: 912271; NCBI Protein GI: 11545723; NCBI Protein Accession: NP_071469; NCBITaxon: 11176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010805, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011209 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant baculoviruses containing the fusion (F) and hemagglutinin-neuraminidase (HN) glycoprotein gene of the viscerotropic velogenic (vv) Newcastle disease virus (NDV) isolate, Kr-005/00, and a lentogenic La Sota strain of the NDV were constructed. A single dose of rNDHN(V) had a protective effect against mortality (p <0.01) in chickens [PubMed: 18716451]." ; rdfs:label "HN hemagglutinin-neuraminidase" ; rdfs:seeAlso "Protegen ID: 625; NCBI Gene GI: 912270; NCBI Protein GI: 11545724; NCBI Protein Accession: NP_071470; NCBITaxon: 11176" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010805, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011210 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers constructed a new recombinant molecule of SERA5, namely SE36. Vaccination of Squirrel monkeys with SE36 protein and aluminium hydroxyl gel (SE36/AHG) conferred protection against high parasitemia and boosted serum anti-SE36 IgG after P. falciparum parasite challenge [PubMed: 20493274]." ; rdfs:label "SERA-5" ; rdfs:seeAlso "Protegen ID: 626; NCBI Protein GI: 238629807; NCBITaxon: 5833" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011211 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination of mice with EAG (2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein) as a single antigen with EtxB (as an adjuvant) induced protection in mice against bacterial challenge, but was less protective than at affording protection than immunization with FNZ, SFS, EAG, and EtxB [PubMed: 15155624]." ; rdfs:label "binding protein Eag" ; rdfs:seeAlso "Protegen ID: 627; NCBI Gene GI: 7696154; NCBI Protein GI: 225870123; NCBI Protein Accession: YP_002746070; NCBITaxon: 553482" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010816, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011212 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers found that the cysteine-rich, carboxyl-terminal region of the MSP-1 protein from the rodent malarial parasite Plasmodium yoelii yoelii can be expressed in a native configuration as a fusion protein in Escherichia coli. This recombinant polypeptide elicits antibodies in mice which recognize the native parasite MSP-1. Most significantly, both inbred and outbred mice immunized with the fusion protein in Ribi adjuvant are partially and in some cases completely protected against challenge infection with an otherwise lethal parasite strain [PubMed: 8363656]." ; rdfs:label "MSP1 from P. yoelii str. 17XNL" ; rdfs:seeAlso "Protegen ID: 628; NCBI Gene GI: 3791597; NCBI Protein GI: 82596427; NCBI Protein Accession: XP_726257; NCBITaxon: 352914" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000386 ] . obo:VO_0011213 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice were immunised i.n. with collagen-binding protein (CNE) and were subsequently subjected to infection with S. equi subsp. equi. A control group of mice was given only adjuvant. The CNE vaccinated group had a delayed onset of infection compared to the control group. Immunization with CNE led to significant protection from infection [PubMed: 16580099]." ; rdfs:label "collagen binding, ancillary pilus subunit Cne" ; rdfs:seeAlso "Protegen ID: 629; NCBI Gene GI: 7695900; NCBI Protein GI: 225870316; NCBI Protein Accession: YP_002746263; NCBITaxon: 553482" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010816, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011214 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Parts of the three recombinant proteins (FNZ (cell surface-bound fibronectin binding protein), SFS (secreted fibronectin binding protein), and EAG (alpha2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein)) were used to immunize mice, either subcutaneously or intranasally, prior to nasal challenge with S. equi subsp. equi. The adjuvant used was EtxB, a recombinant form of the B subunit of Escherichia coli heat-labile enterotoxin. It was shown that nasal colonization of S. equi subsp. equi and weight loss due to infection were significantly reduced after vaccination compared with a mock-vaccinated control group. This effect was more pronounced after intranasal vaccination than after subcutaneous vaccination; nearly complete eradication of nasal colonization was obtained after intranasal vaccination (P < 0.001) [PubMed: 15155624]." ; rdfs:label "Fnz" ; rdfs:seeAlso "Protegen ID: 630; NCBI Gene GI: 7695217; NCBI Protein GI: 225869227; NCBI Protein Accession: YP_002745175; NCBITaxon: 40041" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010816, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011215 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Parts of the three recombinant proteins (FNZ (cell surface-bound fibronectin binding protein), SFS (secreted fibronectin binding protein), and EAG (alpha2-macroglobulin, albumin, and immunoglobulin G [IgG] binding protein)) were used to immunize mice, either subcutaneously or intranasally, prior to nasal challenge with S. equi subsp. equi. The adjuvant used was EtxB, a recombinant form of the B subunit of Escherichia coli heat-labile enterotoxin. It was shown that nasal colonization of S. equi subsp. equi and weight loss due to infection were significantly reduced after vaccination compared with a mock-vaccinated control group. This effect was more pronounced after intranasal vaccination than after subcutaneous vaccination; nearly complete eradication of nasal colonization was obtained after intranasal vaccination (P < 0.001) [PubMed: 15155624]." ; rdfs:label "Sfs" ; rdfs:seeAlso "Protegen ID: 631; NCBI Gene GI: 7696331; NCBI Protein GI: 225869898; NCBI Protein Accession: YP_002745845; NCBITaxon: 553482" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010816, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011216 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The fibrinogen-binding protein (FgBP) reacted with serum taken from horses recovering from strangles and protected mice against lethal challenge from S. equi subsp. equi [PubMed: 9579073]." ; rdfs:label "Fbp" ; rdfs:seeAlso "Protegen ID: 632; NCBI Gene GI: 7697172; NCBI Protein GI: 225871286; NCBI Protein Accession: YP_002747233; NCBITaxon: 553482" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010816, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011217 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers produced a prototypic malaria vaccine based on a highly versatile self-assembling polypeptide nanoparticle (SAPN) platform that can repetitively display antigenic epitopes. Researchers used this platform to display a tandem repeat of the B cell immunodominant repeat epitope (DPPPPNPN)(2)D of the malaria parasite Plasmodium berghei circumsporozoite (CS) protein. Administered in saline, without the need for a heterologous adjuvant, the SAPN construct P4c-Mal conferred a long-lived, protective immune response to mice with a broad range of genetically distinct immune backgrounds including the H-2(b), H-2(d), and H-2(k) alleles. Mice were protected against an initial challenge of parasites up to 6 mo after the last immunization or for up to 15 mo against a second challenge after an initial challenge of parasites had successfully been cleared. [PubMed: 19915055]." ; rdfs:label "CS from P. berghei str. ANKA" ; rdfs:seeAlso "Protegen ID: 633; NCBI Gene GI: 3428738; NCBI Protein GI: 68076353; NCBI Protein Accession: XP_680096; NCBITaxon: 5823" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015475, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011218 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "CS from P. falciparum", "P. falciparum circumsporozoite protein" ; obo:IAO_0000119 "https://www.ncbi.nlm.nih.gov/pubmed/18159254" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A P. berghei parasite line was used to expresses a heterologous circumsporozoite protein (CSP) from P. falciparum. A sterile immunity was obtained by vaccination with the radiation-attenuated P. berghei parasite [PubMed: 18159254]." ; rdfs:label "P. falciparum CSP" ; rdfs:seeAlso "Protegen ID: 634; NCBI Protein GI: 552191; NCBITaxon: 5833" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011219 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study showed that immunization with irradiated sporozoites (IrrSpz) of a P. berghei line whose endogenous CS was replaced by that of P. yoelii conferred sterile protection against challenge with wild type P. berghei sporozoites [PubMed: 19890387]." ; rdfs:label "CS from P. yoelii str. 17XNL" ; rdfs:seeAlso "Protegen ID: 635; NCBI Gene GI: 3830374; NCBI Protein GI: 83317409; NCBI Protein Accession: XP_731149; NCBITaxon: 352914" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000385 ] . obo:VO_0011220 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with a recombinant yeast-expressed Plasmodium falciparum merozoite surface protein 3 (MSP3) protected Aotus nancymai monkeys against a virulent challenge infection [PubMed: 19073223]." ; rdfs:label "MSP3" ; rdfs:seeAlso "Protegen ID: 636; NCBI Protein GI: 113207288; NCBITaxon: 5833" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000130 ] . obo:VO_0011221 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with Plasmodium yoelii merozoite surface protein (PyMSP)-8 protects mice from lethal malaria but does not prevent infection [PubMed: 18097046]." ; rdfs:label "MSP8" ; rdfs:seeAlso "Protegen ID: 637; NCBI Protein GI: 58197887; NCBITaxon: 5861" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011222 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intranasal or oral delivery of the chimeric rotavirus VP6 protein MBP::VP6 to mice elicited >90% reductions in fecal rotavirus shedding after murine rotavirus challenge [PubMed: 17629371]." ; rdfs:label "VP6 from Murine rotavirus" ; rdfs:seeAlso "Protegen ID: 638; NCBI Protein GI: 268080815; NCBITaxon: 28327" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010789, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011223 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with r-Pfen (recombinant P. falciparum enolase protein) showed protection against a challenge with the 17XL lethal strain of the mouse malarial parasite Plasmodium yoelii [PubMed: 17785475]." ; rdfs:label "PF10_0155 enolase" ; rdfs:seeAlso "Protegen ID: 639; NCBI Gene GI: 810313; NCBI Protein GI: 124802328; NCBI Protein Accession: XP_001347440; NCBITaxon: 36329" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011224 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with recombinant PbAMA-1 were partially protected from the challenge of P. berghei [PubMed: 17639690]." ; rdfs:label "AMA-1 from P. berghei" ; rdfs:seeAlso "Protegen ID: 640; NCBI Protein GI: 1438889; NCBITaxon: 5821" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015475, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000330 ] . obo:VO_0011225 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated with recombinant rMSP1 (rPbMSP1), which was generated from Plasmodium berghei, in alum mounted significant protective immunity against challenge infection (P < 0.01). On day 121 after the booster, three out of ten mice immunized with rPbMSP1 in PBS survived parasite infection (P < 0.05) and eight out of ten mice vaccinated with r MSP1 in alum did (P < 0.01). Hence, immunization with MSP1 in alum obviously has conferred protective effects, which prevented death from P. berghei lethal infection in mice (P < 0.01) [PubMed: 17568385]." ; rdfs:label "MSP1 from P. berghei" ; rdfs:seeAlso "Protegen ID: 641; NCBI Protein GI: 1762646; NCBITaxon: 5821" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015475, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011226 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system. Neonates of animals immunized with virus-like particles composed of VP7 assembled on VP6 spherical particles were protected against challenge with the homotypic virus and significantly protected from a heterotypic challenge. Unassembled VP7 protein provided partial protection against challenge [PubMed: 8382422]." ; rdfs:label "VP7 from Bovine rotavirus" ; rdfs:seeAlso "Protegen ID: 642; NCBI Protein GI: 195661008; NCBITaxon: 10927" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010789, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011227 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system. Challenge of neonates born to animals immunized with VP4 protein on assembled particles or in cell lysates showed protection against challenge with both homologous (bovine C486) and heterologous (SA-11) strains of rotavirus [PubMed: 8382422]." ; rdfs:label "VP4 from Bovine rotavirus" ; rdfs:seeAlso "Protegen ID: 643; NCBI Protein GI: 172054621; NCBITaxon: 10927" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010789, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011228 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization of mice with subunit vaccines based on the Plasmodium yoelii 17kDa hepatocyte erythrocyte protein (PyHEP17), orthologue of Plasmodium falciparum exported protein 1 (PfExp1), induces antigen-specific immune responses and protects against sporozoite challenge [PubMed: 17303242]." ; rdfs:label "HEP17" ; rdfs:seeAlso "Protegen ID: 644; NCBI Protein GI: 1399353; NCBITaxon: 5861" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011229 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunized animals were challenged in vivo with various parasite strains or clones of malaria. Immunization with the PfEMP1-DBL1 alpha domain abolished the PfEMP1-dependent sequestration of the homologous strain in immunized rats and substantially inhibited parasite adhesion in immunized monkeys. Protection against sequestration of heterologous parasite strains was also confirmed by direct or indirect challenge in the rat model [PubMed: 17074852]." ; rdfs:label "EMP1" ; rdfs:seeAlso "Protegen ID: 645; NCBI Protein GI: 2961468; NCBITaxon: 5833" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000242 ] . obo:VO_0011230 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization of BALB/c mice and Aotus monkeys with PvMSP-1 induced IgG antibodies (titer > 10(6)) that cross-reacted with P. vivax parasites. Immunized monkeys displayed partial protection against a challenge with P. vivax blood stages [PubMed: 16291762]." ; rdfs:label "MSP1 from P. vivax" ; rdfs:seeAlso "Protegen ID: 646; NCBI Protein GI: 26985160; NCBITaxon: 5855" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011231 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A DNA vaccine based on lysosome-targeted glycoprotein of the rabies virus was evaluated in BALB/c mice. It imparted partial protection (60%) against challenge with 20 LD(50) of the challenge virus standard (CVS) strain of rabies virus [PubMed: 19741168]." ; rdfs:label "Glycoprotein" ; rdfs:seeAlso "Protegen ID: 647; NCBI Protein GI: 56384945; NCBITaxon: 11292" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010788, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011232 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated intraperitoneally (i.p.) with 10^7 p.f.u. of a vaccinia virus recombinant expressing either the glycoprotein (rVac-G) or nucleoprotein (rVac-N) of rabies virus 3 weeks before challenge were protected against peripheral lethal infection [PubMed: 8207400]." ; rdfs:label "RABVgp1 nucleoprotein N" ; rdfs:seeAlso "Protegen ID: 648; NCBI Gene GI: 1489853; NCBI Protein GI: 9627198; NCBI Protein Accession: NP_056793; NCBITaxon: 11292" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010788, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011233 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Two large fragments of PfKbeta representing the N- and C-terminal halves were expressed in E. coli. The recombinant proteins were highly immunogenic in mice, and also found to be the target for immune response in natural infections of Plasmodium spp. Immunization with recombinant PfKbeta fragments was partially protective against a heterologous challenge infection in mice [PubMed: 15987343]." ; rdfs:label "Kbeta" ; rdfs:seeAlso "Protegen ID: 649; NCBI Gene GI: 813054; NCBI Protein GI: 124506397; NCBI Protein Accession: XP_001351796; NCBITaxon: 36329" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011234 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with one of the constructs of M. vaccae expressing OmpA in combination with booster immunization with the homologous recombinant protein protected a significant portion of mice from lethal challenge [PubMed: 11738766]." ; rdfs:label "OmpA" ; rdfs:seeAlso "Protegen ID: 650; NCBI Protein GI: 112710; NCBITaxon: 783" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010846, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011235 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "R. rickettsii OmpB contain B and T lymphocyte epitopes. Immunizations with each of two fragments from OmpB (rompB1550-2738 and rompB2459-4123) conferred protection against challenge with a lethal dose of R. conorii. Protection appeared to be better achieved among the groups that received both DNA and recombinant protein immunizations, although recombinant protein immunizations alone provided some protection [PubMed: 11693887]." ; rdfs:label "OmpB" ; rdfs:seeAlso "Protegen ID: 651; NCBI Protein GI: 6685726; NCBITaxon: 783" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010846, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011236 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Oral immunization of mice with Escherichia coli-expressed Plasmodium yoelii merozoite surface protein 4/5 or the C-terminal 19-kDa fragment of merozoite surface protein 1 induced systemic antibody responses and protected mice against lethal malaria infection [PubMed: 15385527]." ; rdfs:label "MSP4/5" ; rdfs:seeAlso "Protegen ID: 652; NCBI Protein GI: 49798469; NCBITaxon: 73239" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015474, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011237 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with a refolded, recombinant, Plasmodium chabaudi AMA1 fragment (AMA1B) can withstand subsequent challenge with P. chabaudi adami [PubMed: 10861076]." ; rdfs:label "AMA-1 from P. chabaudi" ; rdfs:seeAlso "Protegen ID: 653; NCBI Protein GI: 1469500; NCBITaxon: 5825" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015476, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000389 ] . obo:VO_0011238 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant adenovirus expressing gB (rAd-gB) was found to induce effective protective immunity against a virulent viral infection, regardless of whether it was administered via the muscular or systemic route [PubMed: 19116444]." ; rdfs:label "GB" ; rdfs:seeAlso "Protegen ID: 654; NCBI Protein GI: 4138504; NCBITaxon: 10345" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010800, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011239 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A trial vaccine containing pseudorabies virus (PRV) glycoprotein gC as the main component showed excellent protection against virulent virus infection in pigs [PubMed: 9300361]." ; rdfs:label "UL44 from Pseudorabies virus" ; rdfs:seeAlso "Protegen ID: 655; NCBI Gene GI: 2952505; NCBI Protein GI: 51557513; NCBI Protein Accession: YP_068347; NCBITaxon: 10345" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010800, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011240 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The pseudorabies virus (PrV) DNA vaccine carrying the glycoprotein D (gD) gene delivered by E. coli was able to induce protective immune responses in mice against a lethal PrV challenge [PubMed: 11312026]. Immunization of mice with affinity-purified gD of Aujeszky's disease virus (ADV, Suid herpesvirus 1) induced a strong humoral immune response and protected mice against lethal ADV challenge [PubMed: 17601050]." ; rdfs:label "US6 from Pseudorabies virus" ; rdfs:seeAlso "Protegen ID: 656; NCBI Gene GI: 2952521; NCBI Protein GI: 51557553; NCBI Protein Accession: YP_068387; NCBITaxon: 10345" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010800, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011241 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A monkey vaccination trial using a Plasmodium falciparum protein fraction containing antigens of 90-110 kDa is reported. Three monkeys out of five resisted a heavy challenge dose of highly virulent parasites. Hsp90 was found in the immunoprecipitates obtained with SERP antisera. Interestingly, the response to hsp90 correlated with protection, high antibody titres being found only in the protected monkeys [PubMed: 8303938]." ; rdfs:label "Hsp90" ; rdfs:seeAlso "Protegen ID: 657; NCBI Protein GI: 1093612; NCBITaxon: 5833" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000242 ] . obo:VO_0011242 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "To examine the response by IE180 more closely, a vaccine trial in mice with a vector DNA construct that contains the gene encoding for IE180, designated pcDNAIE180 was conducted. Seven months after immunization with pcDNAIE180, an overall 25% of BALB/c, C3H/HeJ, and C57BL/6 mice receiving a lethal PrV challenge were protected [PubMed: 9586695]." ; rdfs:label "IE180" ; rdfs:seeAlso "Protegen ID: 658; NCBI Gene GI: 2952540; NCBI Protein GI: 51557548; NCBI Protein Accession: YP_068382; NCBITaxon: 10345" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010800, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011243 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "An open reading frame 2 plasmid (pORF2) and the capsid protein (Cap) of PCV2 were used as DNA and subunit vaccines, respectively. In FCM analysis, although pORF2 and Cap alone showed comparable efficacy in eliciting lymphoproliferative responses and Cap-specific CD4(+) T cells, pORF2 was superior to the Cap protein in triggering CD8(+) T cells. Following virus challenge, real-time PCR and histopathological analysis confirmed that only low viral DNA loads and mild microscopic lesions appeared in pORF2-immunized mice [PubMed: 18632956]." ; rdfs:label "ORF2" ; rdfs:seeAlso "Protegen ID: 659; NCBI Protein GI: 78217439; NCBITaxon: 85708" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010799, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011244 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "To examine the mechanism of immunity in vivo, researchers used poliovirus receptor-transgenic mice on a BALB/c (H-2d) background. Mice immunized with the vaccine strain were protected against a subsequent challenge with wild-type virus. Protection was observed when mice received primed B cells in the presence of a VP4-specific Th1 clone. Findings demonstrate that CD4+ T cells, specific for the internal poliovirus capsid protein, VP4, can provide effective help for a protective antibody response directed against surface capsid proteins [PubMed: 7699320]." ; rdfs:label "VP4 from Poliovirus" ; rdfs:seeAlso "Protegen ID: 660; NCBI Protein GI: 68532656; NCBITaxon: 12080" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010787, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011245 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Series of plasmid constructs encoding different forms of the envelope glycoprotein E of the flavivirus tick-borne encephalitis virus were constructed. These included a secreted recombinant subviral particle, a secreted carboxyl-terminally truncated soluble homodimer, a nonsecreted full-length form, and an inefficiently secreted truncated form. Mice were immunized using both i.m. injection and Gene Gun-mediated application of plasmids. The functional immune response was evaluated by determining specific neutralizing and hemagglutination-inhibiting Ab activities and by challenging the mice with a lethal dose of the virus.The plasmid construct encoding a secreted subviral particle, which carries multiple copies of the protective Ag on its surface, was superior to the other constructs in terms of extent and functionality of the Ab response as well as protection against virus challenge [PubMed: 10586074]." ; rdfs:label "TBEVgp1 polyprotein" ; rdfs:seeAlso "Protegen ID: 661; NCBI Gene GI: 1489719; NCBI Protein GI: 9628432; NCBI Protein Accession: NP_043135; NCBITaxon: 11084" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010793, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011246 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Monoclonal antibodies to gE neutralize VZV in vitro in a complement- dependent manner [PubMed: 9125048]. Guinea pigs immunized with recombinant varicella-zoster virus (VZV) glycoproteins E (gE) and I (gI) developed antigen-specific antibodies in the sera, vitreous, and conjunctival washes. Sera from immunized animals neutralized both cell-free and cell-associated VZV, and peripheral blood lymphocytes proliferated in vitro in response to recombinant gE and gI and to antigens from VZV-infected cells. Immunized guinea pigs were inoculated intravitreally with VZV, which induces chronic uveitis. VZV DNA was more rapidly cleared and infectious VZV was isolated less frequently from the retinas of animals immunized with gE and gI compared with that in controls receiving adjuvant alone [PubMed: 9697709]." ; rdfs:label "ORF68" ; rdfs:seeAlso "Protegen ID: 662; NCBI Gene GI: 1487709; NCBI Protein GI: 9625942; NCBI Protein Accession: NP_040190; NCBITaxon: 10335" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010792, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011247 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Monoclonal antibodies to gI neutralize VZV in vitro in a complement- dependent manner [PubMed: 3021804]. Guinea pigs immunized with recombinant varicella-zoster virus (VZV) glycoproteins E (gE) and I (gI) developed antigen-specific antibodies in the sera, vitreous, and conjunctival washes. Sera from immunized animals neutralized both cell-free and cell-associated VZV, and peripheral blood lymphocytes proliferated in vitro in response to recombinant gE and gI and to antigens from VZV-infected cells. Immunized guinea pigs were inoculated intravitreally with VZV, which induces chronic uveitis. VZV DNA was more rapidly cleared and infectious VZV was isolated less frequently from the retinas of animals immunized with gE and gI compared with that in controls receiving adjuvant alone [PubMed: 9697709]." ; rdfs:label "ORF67" ; rdfs:seeAlso "Protegen ID: 663; NCBI Gene GI: 1487689; NCBI Protein GI: 9625941; NCBI Protein Accession: NP_040189; NCBITaxon: 10335" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010792, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011248 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 was administered to pigs to determine if it would have a greater protective effect than a vector containing the gene for gp50 alone. Both NYVAC vectors protected pigs similarly from virulent pseudorabies virus challenge [PubMed: 8904669]." ; rdfs:label "Gp50" ; rdfs:seeAlso "Protegen ID: 664; NCBI Protein GI: 2440155; NCBITaxon: 10345" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010800, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011249 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 was administered to pigs to determine if it would have a greater protective effect than a vector containing the gene for gp50 alone. Both NYVAC vectors protected pigs similarly from virulent pseudorabies virus challenge [PubMed: 8904669]." ; rdfs:label "GII" ; rdfs:seeAlso "Protegen ID: 665; NCBI Protein GI: 1335775; NCBITaxon: 10345" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010800, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011250 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with either gII, gIII, gVI antigen or a mixture of them were challenged intraperitoneally with 8.5 x 10(3) plaque forming units of PRV. All the mice immunized with 1.5 and 4.5 micrograms of the mixture and 4.5 micrograms of the gIII antigen survived [PubMed: 1322712]." ; rdfs:label "GIII" ; rdfs:seeAlso "Protegen ID: 667; NCBI Protein GI: 334050; NCBITaxon: 10345" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010800, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011251 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination of mice with fusion proteins containing the N terminus of gI from Suid herpesvirus 1 are able to confer protection to mice against a lethal challenge of PRV [PubMed: 1693164]." ; rdfs:label "GI" ; rdfs:seeAlso "Protegen ID: 668; NCBI Protein GI: 255957222; NCBITaxon: 10345" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010800, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011252 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A recombinant, vP869, expressing prM and E induced high titers of neutralizing and hemagglutination inhibiting antibodies in mice and was protective against intracranial challenge with the French neurotropic strain of YFV [PubMed: 1736531]." ; rdfs:label "E (envelope glycoprotein)" ; rdfs:seeAlso "Protegen ID: 669; NCBI Protein GI: 262283879; NCBITaxon: 11089" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010791, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011253 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Horses were vaccinated with adjuvanted recombinant SnSAG1 (rSnSAG1)and 5 control (sham vaccinated) horses were vaccinated with adjuvant only. The effect of vaccination with rSnSAG1 on in vivo infection by S. neurona was evaluated by challenging all the horses with S. neurona merozoites. The study showed that vaccination with rSnSAG-1 produced antibodies in horses that neutralized merozoites when tested by in vitro culture and significantly reduced clinical signs demonstrated by in vivo challenge [PubMed: 19794889]." ; rdfs:label "SAG1 from Sarcocystis neurona" ; rdfs:seeAlso "Protegen ID: 672; NCBI Protein GI: 295682690; NCBITaxon: 42890" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010830, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000336 ] . obo:VO_0011254 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Both inbred BALB/c and outbred CD-1 mice were immunized with rotavirus VP2/6-rVLPs (2/6-VLPs) combined with CT-E29H, orally or intranasally (i.n.), and the comparative efficacy of different formulations was then determined. Two immunizations with 2-6VLPs and CT-E29H were sufficient to protect BALB/c mice, regardless of the route of administration [PubMed: 11270595]." ; rdfs:label "VP2 from Rotavirus" ; rdfs:seeAlso "Protegen ID: 673; NCBI Protein GI: 431460; NCBITaxon: 10970" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010789, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011255 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Plasmid DNA vaccines encoding for murine rotaviral proteins VP4, VP6, and VP7 were tested in adult BALB/c mice for their ability to induce immune responses and provide protection against rotavirus challenge. Vaccines encoding VP4 were effective in protecting mice against infection after rotavirus (100 ID50) challenge [PubMed: 9015117]." ; rdfs:label "VP4 from Murine rotavirus" ; rdfs:seeAlso "Protegen ID: 675; NCBI Protein GI: 475695; NCBITaxon: 28327" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010789, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011256 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Plasmid DNA vaccines encoding for murine rotaviral proteins VP4, VP6, and VP7 were tested in adult BALB/c mice for their ability to induce immune responses and provide protection against rotavirus challenge. Vaccines encoding VP7 were effective in protecting mice against infection after rotavirus (100 ID50) challenge [PubMed: 9015117]." ; rdfs:label "VP7 from Murine rotavirus" ; rdfs:seeAlso "Protegen ID: 676; NCBI Protein GI: 475697; NCBITaxon: 28327" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010789, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011257 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "VP6 derived from Group A rotavirus conferred in vivo partial protection against rotavirus challenge in a neonatal mouse model [PubMed: 18632867]." ; rdfs:label "VP6 from Rotavirus A" ; rdfs:seeAlso "Protegen ID: 677; NCBI Gene GI: 7011372; NCBI Protein GI: 210136699; NCBI Protein Accession: YP_002302229; NCBITaxon: 28875" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010789, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011258 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system. Challenge of neonates born to animals immunized with VP6 protein showed partial protection [PubMed: 8382422]." ; rdfs:label "VP6 from Bovine rotavirus" ; rdfs:seeAlso "Protegen ID: 678; NCBI Protein GI: 195661002; NCBITaxon: 10927" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010789, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011259 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Protection from lethal viral infection has been achieved with passively administered monoclonal antibody specific for flavivirus glycoprotein NS1 [PubMed: 1736531]. Immunization of monkeys with yellow fever virus-specified nonstructural protein NS1 resulted in protection against fatal hepatitis as well as marked reduction in the magnitude of viremia after subcutaneous challenge with yellow fever virus [PubMed: 3783816]." ; rdfs:label "NS1 (non-structural protein 1)" ; rdfs:seeAlso "Protegen ID: 684; NCBITaxon: 11089" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010791, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011260 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge. A truncated portion of the LACK antigen (LACKp24) was able to induce the highest protective effect compared to other constructs. The DNA vaccine encoding LACK was able to induce partial protection in mice [PubMed: 18951941]." ; rdfs:label "LACK" ; rdfs:seeAlso "Protegen ID: 734; NCBI Nucleotide GI: 1276476; NCBI Protein GI: 1276477; NCBI Protein Accession: AAA97577.1; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011261 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study compared the handling of overlapping 24-mer peptides from HIV Nef either mixed or covalently linked in tandem in one protein. With adjuvant, overlapping peptides were capable of protecting Balb/c mice against lethal viral challenge with 3 108 plaque forming units of vv-nef, whereas the intact protein was less protective [PubMed: 19193636]." ; rdfs:label "Nef" ; rdfs:seeAlso "Protegen ID: 707; NCBI Gene GI: 156110; NCBI Protein GI: 28872818; NCBI Protein Accession: NP_057857; NCBITaxon: 11676" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010767, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011262 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "HIV-1 DNA plasmids expressing Env, Gag and Tat, either alone or combined with the corresponding protein immunogens formulated in the MF59 adjuvant, resulted in protection against an experimental HIV-1 infection in C57Bl/6 mice [PubMed: 17707956]." ; rdfs:label "Tat" ; rdfs:seeAlso "Protegen ID: 711; NCBI Gene GI: 155871; NCBI Protein GI: 9629358; NCBI Protein Accession: NP_057853; NCBITaxon: 11676" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010767, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011263 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "HIV-1 DNA plasmids expressing Env, Gag and Tat, either alone or combined with the corresponding protein immunogens formulated in the MF59 adjuvant, resulted in protection against an experimental HIV-1 infection in C57Bl/6 mice [PubMed: 17707956]." ; rdfs:label "Gag from HIV 1" ; rdfs:seeAlso "Protegen ID: 713; NCBI Gene GI: 155030; NCBI Protein GI: 9629360; NCBI Protein Accession: NP_057850; NCBITaxon: 11676" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010767, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011264 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with Recombinant-derived nucleoprotein (rNP) from S. typhimurium expressing the cloned NP gene from A/NT/60/68 (Jones & Brownlee, 1985) were protected against a lethal challenge with Influenza A/Puerto Rico/8/34 (A/PR8) virus but showed considerable morbidity before recovery [PubMed: 2172156]." ; rdfs:label "NP from Influenza A virus (A/nt/60/1968(H3N2))" ; rdfs:seeAlso "Protegen ID: 718; NCBI Protein GI: 324704; NCBITaxon: 384505" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011265 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Since the E2 amino-terminal sequence for all VEE subtype viruses is conserved, we tested the protective capacity in mice of passively transferred mAb 1A2B-10 and found it to protect from both epizootic and enzootic VEE virus challenge. Since horses are an important natural host for VEE virus, pep1-19 was used to immunize horses and was found to be immunogenic and to elicit virus-reactive antibody [PubMed: 7543231]." ; rdfs:label "E2 envelope protein" ; rdfs:seeAlso "Protegen ID: 725; NCBI Protein GI: 25140296; NCBITaxon: 11036" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010774, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011266 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study demonstrated that a recombinant construction of heat-shock protein (hslU) with lypopolysaccharide (rcHSP-LPS) administered 24 hours before inoculation induced resistance to S. typhimurium infection. Protection formed after 3 injections of rcHSP-LPS with 10 mcg in each or single injection with 100 mcg/mouse. Forty to eighty percent of immunized mice survived after challenge while 90% of control animals died. Destruction of the HSP by boiling of the construction led to loss of protective effect [PubMed: 19621817]." ; rdfs:label "HslU" ; rdfs:seeAlso "Protegen ID: 726; NCBI Protein GI: 9650897; NCBITaxon: 90371" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010776, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011267 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The monoclonal antibody against E1 glycoprotein protect outbred albino mice from lethal infection caused by the virulent strain Trd of the VEE virus [PubMed: 7529989]." ; rdfs:label "E1 glycoprotein" ; rdfs:seeAlso "Protegen ID: 727; NCBI Protein GI: 798795; NCBITaxon: 11036" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010774, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011268 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunisation of mice with DnaJ derived from Salmonella enterica subsp. enterica serovar Typhi str. CT18 was found to provide 70% protection against lethal challenge by S. Typhimurium indicating the possible use of DnaJ as vaccine candidate against typhoid [PubMed: 16887241]." ; rdfs:label "DnaJ" ; rdfs:seeAlso "Protegen ID: 728; NCBI Gene GI: 1246524; NCBI Protein GI: 16759006; NCBI Protein Accession: NP_454623; NCBITaxon: 220341" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010776, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011269 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The viaB (tviB) gene coding for the Vi antigen of Salmonella typhi Ty2 was subcloned into expression vector pYA248. The recombinant plasmid was termed SMM202 and transformed into Salmonella typhimurium 4072, an attenuated crp mutant. Immunization of mice with Vi4072 afforded complete protection against fatal infection with virulent S. typhi Ty2 [PubMed: 1612747]." ; rdfs:label "TviB" ; rdfs:seeAlso "Protegen ID: 729; NCBI Gene GI: 1067316; NCBI Protein GI: 29144603; NCBI Protein Accession: NP_807945; NCBITaxon: 209261" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010776, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011270 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The immune sera elicited by CTB DNA vaccine were functional and protective against V. cholerae O1 infection in mice [PubMed: 19443090]." ; rdfs:label "CtxB" ; rdfs:seeAlso "Protegen ID: 731; NCBI Protein GI: 110264635; NCBITaxon: 127906" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010848, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011271 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Antibodies against TCP were able to protect baby mice against challenge with V. cholerae O1 of the classical but not of the El Tor biotype [PubMed: 7911787]." ; rdfs:label "TcpA" ; rdfs:seeAlso "Protegen ID: 732; NCBI Protein GI: 21616882; NCBITaxon: 127906" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010848, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011272 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Antibodies generated against TcpF are protective against experimental V. cholerae infection in the infant mouse cholera model [PubMed: 16040956]." ; rdfs:label "TcpF" ; rdfs:seeAlso "Protegen ID: 733; NCBI Gene GI: 2614504; NCBI Protein GI: 15640854; NCBI Protein Accession: NP_230485; NCBITaxon: 243277" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010848, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011273 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major. Mice inoculated pCMV3ISS-TSA developed significantly smaller lesions in their footpads after challenge with the parasite. The vaccine was able to induce a partially protective effect [PubMed: 18951941]." ; rdfs:label "TSA from Leishmania major" ; rdfs:seeAlso "Protegen ID: 735; NCBI Nucleotide GI: 3411093; NCBI Protein GI: 3411094; NCBI Protein Accession: AAC31146.1; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011274 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major. Mice inoculated pCMV3ISS-LmSTI1 developed significantly smaller lesions in their footpads after challenge with the parasite. The vaccine was able to induce a partially protective effect [PubMed: 18951941]." ; rdfs:label "LmSTI1" ; rdfs:seeAlso "Protegen ID: 736; NCBI Nucleotide GI: 1698879; NCBI Protein GI: 1698880; NCBI Protein Accession: AAB37318.1; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011275 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers evaluated the potency of different DNA vaccine candidates in BALB/c mice using high dose footpad parasite challenge with L. major. Mice inoculated pCMV3ISS-CPa developed significantly smaller lesions in their footpads after challenge with the parasite. The vaccine was able to induce a partially protective effect [PubMed: 18951941]." ; rdfs:label "Cpa" ; rdfs:seeAlso "Protegen ID: 737; NCBI Nucleotide GI: 71084305; NCBI Protein GI: 71084306; NCBI Protein Accession: AAZ23598.1; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011276 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The potential protection of Lmjsp (Leishmania major signal peptidase) was evaluated in three different vaccination strategies (DNA/DNA, Protein/Protein and DNA/Protein), against L. major infection. We demonstrated that vaccination with SPase through all three mentioned strategies induced a parasite specific Th1 response and conferred partial protection against parasite challenge. However, our results indicated that DNA/DNA strategy developed more effective protective responses than the other two approaches and induced 81% reduction in L. major parasite load [PubMed: 16481076]." ; rdfs:label "SP" ; rdfs:seeAlso "Protegen ID: 738; NCBI Protein GI: 23168331; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011277 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers tested the ability of the entire H2B protein of L. major, its divergent or conserved regions to provide protection against virulent L. major challenge. The divergent amino-terminal region of H2B is able to confer potent protection against a virulent challenge in BALB/c mice [PubMed: 16417957]." ; rdfs:label "H2B" ; rdfs:seeAlso "Protegen ID: 739; NCBI Protein GI: 13384083; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011278 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Cell-mediated immunity to Leishmania major (L. major) was induced by injecting BALB/c mice intradermally with plasmid DNA expressing the conserved L. major cell surface glycoprotein gp63 (gp63-pcDNA-3). Challenge studies revealed that gp63-pcDNA-3 vaccination protected 30% of susceptible mice (21 of 70) from Leishmania infection [PubMed: 9741428]." ; rdfs:label "Gp63" ; rdfs:seeAlso "Protegen ID: 741; NCBI Protein GI: 259011719; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011279 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intraperitoneal vaccination of C3H/He mice with PSA-2 with Corynebacterium parvum as an adjuvant resulted in complete protection from lesion development after challenge infection with virulent L. major. Significant protection was also obtained in the genetically susceptible BALB/cH-2k and BALB/c mice [PubMed: 7591056]." ; rdfs:label "PSA-2" ; rdfs:seeAlso "Protegen ID: 742; NCBI Protein GI: 1129058; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011280 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In a murine model of experimental cutaneous leishmaniasis, researchers investigated the protection elicited by injection of histone H1 (SW3.1) isolated from parasites by perchloric extraction, of a H1 recombinant protein produced in E. coli, and of H1 long and short synthetic peptides, against infection by L. major. Partial protection was achieved in most of the animals as shown by reduction in lesion size, upon immunization with histone H1 or its peptides, provided that the region 1-60 was present in the molecule [PubMed: 10580198]." ; rdfs:label "SW3.1" ; rdfs:seeAlso "Protegen ID: 743; NCBI Protein GI: 4008565; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011281 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Together with poloxamer 407 as adjuvant the recombinant type I (rCPB) cysteine proteinase of Leishmania major was screened as a potential vaccines against L. major in a mouse model. Using the footpad thickness increase to monitor the clinical outcome/cutaneous lesion at site of L. major delivery, it was possible to document that rCPB allowed BALB/c mice to mount a partial protective response [PubMed: 12057598]." ; rdfs:label "Cpb" ; rdfs:seeAlso "Protegen ID: 744; NCBI Protein GI: 54287314; NCBITaxon: 5664" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010835, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011282 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Upon challenge with L. infantum, C57BL/6 mice immunized with SMT formulated in MPL-SE adjuvant showed significantly lower parasite burdens in both spleens and livers compared with non-immunized mice or mice injected with adjuvant alone [PubMed: 17804125]." ; rdfs:label "SMT" ; rdfs:seeAlso "Protegen ID: 745; NCBI Protein GI: 146104463; NCBITaxon: 435258" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010836, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011283 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study examined the immunogenic properties of the Leishmania infantum acidic ribosomal protein P0 (LiP0) in the BALB/c mouse model. When mice were immunized with pcDNA3-LiP0, noticeable protection against L. major infection was achieved [PubMed: 14573678]." ; rdfs:label "LIPO-A" ; rdfs:seeAlso "Protegen ID: 746; NCBI Protein GI: 730579; NCBITaxon: 5671" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010836, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011284 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB/c mice immunized with a DNA vector expressing p36/LACK of Leishmania infantum followed by a booster with VVp36/LACK induced significant protection against Leishmania major infection [PubMed: 11489418]." ; rdfs:label "P36/LACK" ; rdfs:seeAlso "Protegen ID: 747; NCBI Protein GI: 134085114; NCBITaxon: 5671" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010836, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011285 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following infection with L. infantum promastigotes, five out of eight beagle dogs immunized with H1 Montanide remained free of clinical signs, compared to two out of eight dogs in the control group. The results demonstrate that H1 antigens with Montanide were able to induce partial protection against canine leishmaniasis, even under extreme experimental challenge conditions [PubMed: 17576026]." ; rdfs:label "H1" ; rdfs:seeAlso "Protegen ID: 748; NCBI Nucleotide GI: 78146499; NCBI Protein GI: 78146500; NCBI Protein Accession: ABB22792.1; NCBITaxon: 5671" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010836, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011286 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following infection with L. infantum promastigotes, four out of eight beagle dogs immunized with HASPB1 Montanide remained free of clinical signs, compared to two out of eight dogs in the control group. The results demonstrate that HASPB1 antigens with Montanide were able to induce partial protection against canine leishmaniasis, even under extreme experimental challenge conditions [PubMed: 17576026]." ; rdfs:label "HASPB1" ; rdfs:seeAlso "Protegen ID: 749; NCBI Nucleotide GI: 3724133; NCBI Protein GI: 3724134; NCBI Protein Accession: CAA09789.1; NCBITaxon: 5661" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010836, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011287 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In 1923, it was discovered that treatment with formalin eliminated the toxicity of diphtheria toxin (DT) without destroying its immunogenicity. Formalinreated DT, now called diphtheria toxoid, rapidly became the preferred vaccine against diphtheria, and diphtheria toxoid (usually in combined vaccines, such as diphtheriaetanus toxoidsertussis vaccine [DTP] or diphtheriaetanus toxoidscellular pertussis vaccine [DTaP] for children and tetanusiphtheria toxoids vaccine for adults [Td]) is still used throughout the world for active immunization against diphtheria [PubMed: 10657208]." ; rdfs:label "Tox" ; rdfs:seeAlso "Protegen ID: 750; NCBI Protein GI: 38199106; NCBITaxon: 1717" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010798, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011288 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Susceptible BALB/c mice were immunized with the DNA encoding P4 alone, P4/IL-12, or P4/HSP70 prior to challenge with L. amazonensis promastigotes. Mice immunized with P4 alone had a delayed onset of lesion development and significantly smaller lesions than the infection control group at 11 weeks postinfection (P < 0.05). P4/IL-12 immunized animals showed no sign of lesion development in three independent experiments (P < 0.01). Our results indicate that different vaccine combinations, including DNA encoding P4, HSP70, or IL-12, can provide significant protection against both Old World and New World cutaneous leishmaniasis [PubMed: 14573646]." ; rdfs:label "P4 from Leishmania amazonensis" ; rdfs:seeAlso "Protegen ID: 751; NCBI Nucleotide GI: 29165286; NCBI Protein GI: 29165287; NCBI Protein Accession: AAO65599.1; NCBITaxon: 5659" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010837, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011289 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "To examine the efficacy of a new mode of recombinant viral vaccine, a vaccine was constructed of two non-transmissible Sendai viruses (rSeV/dF) encoding the full-length parasite antigen amastigote surface protein-2 (ASP2) or ASP2 fused with a mono-ubiquitin on its N-terminus (UASP2). C57BL/6 mice immunized intranasally with rSeV/dF expressing either ASP2 or UASP2 showed significantly suppressed parasitemia and could be protected from lethal T. cruzi challenge [PubMed: 19712768]." ; rdfs:label "T. cruzi amastigote surface protein-2" ; rdfs:seeAlso "Protegen ID: 752; NCBI Protein GI: 284180153; NCBITaxon: 5693" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011290 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "DNA vaccination in BALB/c mice with the LAWD (for Leishmania antigenic WD protein) and IL-12 genes significantly delayed lesion development from challenge with Leishmania amazonensis, which correlated with a dramatic reduction in parasite burdens [PubMed: 15039343]." ; rdfs:label "WD" ; rdfs:seeAlso "Protegen ID: 753; NCBI Nucleotide GI: 38455440; NCBI Protein GI: 38455441; NCBI Protein Accession: AAR20840.1; NCBITaxon: 5659" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010837, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011291 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization of CBA mice with the M-2 glycoprotein of L. amazonensis and C. parvum adjuvant resulted in complete protection against a challenge infection of 10^4 and 10^6 late log-phase promastigotes of L. amazonensis. In the BALB/c strain, complete protection was observed in some of the immunized animals (28 to 50%); in the rest of the mice the onset of infection was significantly delayed. Protective immunity for C57BL/6 mice was observed only at the low infecting dose (10(4) L. amazonensis organisms) [PubMed: 3182080]." ; rdfs:label "M2" ; rdfs:seeAlso "Protegen ID: 754; NCBI Nucleotide GI: 2828562; NCBI Protein GI: 2828563; NCBI Protein Accession: AAC08302.1; NCBITaxon: 5659" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010837, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011292 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "cDNAs encoding L. m. amazonensis gp46 antigen were subcloned into the VR1012 plasmid, and susceptible BALB/c mice were immunised with two i.m. injections of 100 microg of plasmid DNA. Mice were challenged by the injection of 4 x 10^6 L. m. mexicana parasites in the foot pad to evaluate protection. Measurement of lesion size indicated that mice immunised with VR012-GP46 were partially protected against infection [PubMed: 11713811]." ; rdfs:label "Gp46" ; rdfs:seeAlso "Protegen ID: 755; NCBI Nucleotide GI: 159320; NCBI Protein GI: 159321; NCBI Protein Accession: AAA29234.1; NCBITaxon: 5659" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010837, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011293 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "To study the protective effects in vivo of cruzipain-specific Th1 responses against systemic T. cruzi challenges, mice were immunized with recombinant cruzipain plus interleukin 12 (IL-12) and a neutralizing anti-IL-4 MAb. These immunized mice developed potent cruzipain-specific memory Th1 cell responses and were significantly protected against normally lethal systemic T. cruzi challenges. To study whether cruzipain could induce mucosal immune responses relevant for vaccine development, recombinant attenuated Salmonella enterica serovar Typhimurium vaccines expressing cruzipain were prepared. BALB/c mice immunized with salmonella expressing cruzipain were significantly protected against T. cruzi mucosal infection [PubMed: 12183554]." ; rdfs:label "T. cruzi Cruzipain" ; rdfs:seeAlso "Protegen ID: 756; NCBI Protein GI: 1136308; NCBITaxon: 5693" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011294 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "To develop a vaccine strategy taking advantage of activated CD8(+)T cells,a DNA vaccine, designated pGFP-TSA1, encoding a fusion protein linking GFP to a single CTL epitope of TSA1(TS), a leading candidate for vaccine against T. cruzi was constructed. C57BL/6 mice vaccinated with this plasmid showed suppressed parasitemia and prolonged survival. Vaccination with pGFP-TSA1 enhanced epitope-specific cytotoxicity and IFN-gamma secretion by CD8(+)T cells [PubMed: 18321749]." ; rdfs:label "T. cruzi TS" ; rdfs:seeAlso "Protegen ID: 757; NCBI Protein GI: 258547365; NCBITaxon: 5693" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011295 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A 500 bp fragment encoding an isoform of cysteine proteinase (CP) from Leishmania (Leishmania) amazonensis was subcloned and expressed in the pHis vector, resulting in a recombinant protein of 24 kDa, rLacys24. Immunization of BALB/c mice with rLacys24 plus CFA adjuvant resulted in a low but significant decrease of foot lesions after challenge with L. (L.) amazonensis compared to those exhibited by control mice [PubMed: 19735658]." ; rdfs:label "CP cysteine proteinase" ; rdfs:seeAlso "Protegen ID: 758; NCBI Nucleotide GI: 30142041; NCBI Protein GI: 30142042; NCBI Protein Accession: AAN34826.1; NCBITaxon: 5659" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010837, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011296 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Following the intramuscular immunization of H-2(b) and H-2(d) mice with a plasmid DNA encoding an N-terminally truncated TSA-1 lacking or containing the C-terminal nonapeptide tandem repeats, the antibody level, CTL response, and protection against challenge with T. cruzi were assessed. In H-2(b) mice, antiparasite antibodies were induced only by immunization with the DNA construct encoding TSA-1 containing the C-terminal repeats. However, both DNA constructs were efficient in eliciting long-lasting CTL responses against the protective H-2Kb-restricted TSA-1515-522 epitope. In H-2(d) mice, inoculation with either of the two TSA-1-expressing vectors effectively generated antiparasite antibodies and primed CTLs that lysed T. cruzi-infected cells in an antigen-specific, MHC class I-restricted, and CD8(+)-T-cell-dependent manner. When TSA-1 DNA-vaccinated animals were challenged with T. cruzi, 14 of 22 (64%) H-2(b) and 16 of 18 (89%) H-2(d) mice survived the infection [PubMed: 9784506]." ; rdfs:label "T. cruzi TSA-1" ; rdfs:seeAlso "Protegen ID: 759; NCBI Protein GI: 162315; NCBITaxon: 5693" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011297 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A complement regulatory protein (CRP) of Trypanosoma cruzi was evaluated as a vaccine candidate in a murine model of experimental T. cruzi infection. Recombinant CRP derived from an Escherichia coli expression system and a plasmid encoding the full-length crp structural gene under the control of a eukaryotic promoter were used to immunize BALB/c mice. Immunization with both protein and DNA vaccines resulted in a Th1-type T-cell response, comparable antibody titers, and similar immunoglobulin G isotype profiles. Only mice immunized with the crp DNA plasmid produced antibodies capable of lysing the parasites in the presence of complement and were protected against a lethal challenge with T. cruzi trypomastigotes [PubMed: 10948115]." ; rdfs:label "T. cruzi CRP-10" ; rdfs:seeAlso "Protegen ID: 760; NCBI Protein GI: 1389837; NCBITaxon: 5693" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011298 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The vaccine efficacy of a putative candidate antigen against T. cruzi infection and disease in a mouse model. C57BL/6 mice vaccinated with a T. cruzi G4-encoding plasmid and cytokine (interleukin-12 and granulocyte-macrophage colony-stimulating factor) expression plasmids elicited a strong Th1-type antibody response dominated by immunoglobulin G2b (IgG2b)/IgG1 isotypes. The dominant IgG2b/IgG1 antibody response was maintained after a challenge infection and was associated with 90% control of the acute-phase tissue parasite burden and an almost undetectable level of tissue parasites during the chronic phase, as determined by a sensitive T. cruzi 18S rRNA gene-specific real-time PCR approach [PubMed: 18550728]." ; rdfs:label "T. cruzi G4" ; rdfs:seeAlso "Protegen ID: 761; NCBI Protein GI: 52424038; NCBITaxon: 5693" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011299 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The vaccine efficacy of a putative candidate antigen against T. cruzi infection and disease in a mouse model. C57BL/6 mice vaccinated with a T. cruzi G2-encoding plasmid and cytokine (interleukin-12 and granulocyte-macrophage colony-stimulating factor) expression plasmids elicited a strong Th1-type antibody response dominated by immunoglobulin G2b (IgG2b)/IgG1 isotypes. The dominant IgG2b/IgG1 antibody response was maintained after a challenge infection and was associated with 50% control of the acute-phase tissue parasite burden and an almost undetectable level of tissue parasites during the chronic phase, as determined by a sensitive T. cruzi 18S rRNA gene-specific real-time PCR approach [PubMed: 18550728]." ; rdfs:label "T. cruzi G2" ; rdfs:seeAlso "Protegen ID: 762; NCBI Protein GI: 205278890; NCBITaxon: 5693" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011300 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Tc00.1047053434931.10" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "C57BL/6 mice were immunized s.c. with recombinant PFR-2 (PAR2) protein co-adsorbed to alum with rIL-12. rPFR-2 immunized animals were able to successfully resolve parasitemia by day 30 p.i., with the peak parasitemia occurring between days 17 and 21 p.i. [PubMed: 12798650]." ; rdfs:label "T. cruzi PAR2" ; rdfs:seeAlso "Protegen ID: 763; NCBI Gene GI: 3532027; NCBI Protein GI: 71398801; NCBI Protein Accession: XP_802646; NCBITaxon: 353153" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011301 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "C57BL/6 mice were immunized s.c. with recombinant PFR-1 (PAR1) protein co-adsorbed to alum with rIL-12. rPFR-1 immunized animals were able to successfully resolve parasitemia by day 30 p.i., with the peak parasitemia occurring between days 17 and 21 p.i. [PubMed: 12798650]." ; rdfs:label "T. cruzi PAR1" ; rdfs:seeAlso "Protegen ID: 764; NCBI Protein GI: 2209137; NCBITaxon: 5693" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000164 ] . obo:VO_0011302 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Skin and mucosal vaccination of ponies with HA from influenza virus A/equine/Ky/1/81 provided complete protection from clinical signs of infection after challenge, while skin vaccination provided partial protection; DNA vaccination provided partial protection from viral shedding [PubMed: 10403592]." ; rdfs:label "HA from Influenza A virus (A/equine/Kentucky/1/1981(H3N8))" ; rdfs:seeAlso "Protegen ID: 765; NCBI Nucleotide GI: 166079523; NCBI Protein GI: 166079524; NCBI Protein Accession: ABY81481.1; NCBITaxon: 475467" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010782, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011303 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Flagellin encoding plasmid DNA was injected into Balb/c mice intramuscularly and this elicited both a humoral and a cellular immune response. Subsequent intravenous challenge of the vaccinated Balb/c mice with 10^5CFU of B. pseudomallei resulted in the number of bacterial cells detected in liver and/or spleen being significantly reduced in the flagellin plasmid DNA vaccinated mice. At 7 days subsequent to infection of B. pseudomallei, 5/6 (83%) of flagellin plasmid DNA vaccinated mice had survived [PubMed: 16169637]." ; rdfs:label "FliC" ; rdfs:seeAlso "Protegen ID: 770; NCBI Protein GI: 1929918; NCBITaxon: 28450" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010840, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011304 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Transgenic rice immunization expressing the Chlamydophila psittaci (Cp. psittaci) antigen (MOMP) fused to the B subunit of Escherichia coli heat-labile enterotoxin (LTB) induced partial protection (53.3%) against a lethal challenge with the highly virulent Cp. psittaci 6BC strain in a BALB/c mouse model [PubMed: 19146896]." ; rdfs:label "MOMP from C. psittaci 6BC" ; rdfs:seeAlso "Protegen ID: 771; NCBI Nucleotide GI: 40568; NCBI Protein GI: 40569; NCBI Protein Accession: CAA40300.1; NCBITaxon: 331636" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010839, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011305 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "This report describes the successful cloning of the E2 gene of WEEV and expression in Escherichia coli as inclusion bodies. The immunogenicity of the refolded rE2 protein was demonstrated by strong humoral and cell mediated immune (CMI) responses in rE2-immunized BALB/c mice. The current study also demonstrated that rE2-immunized mice could be partially protected from lethal challenge of WEEV [PubMed: 17499379]." ; rdfs:label "E2 from Western equine encephalomyelitis virus" ; rdfs:seeAlso "Protegen ID: 773; NCBI Protein GI: 29611992; NCBITaxon: 11039" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010841, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011306 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain [PubMed: 19923571]. Note: The E1 glycoprotein is part of the 6K-E1 structural protein""" ; rdfs:label "E1" ; rdfs:seeAlso "Protegen ID: 774; NCBI Nucleotide GI: 17148716; NCBI Protein GI: 17148717; NCBI Protein Accession: AAL35792.1; NCBITaxon: 11039" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010841, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011307 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain [PubMed: 19923571]. Note: The 6K protein is part of the 6K-E1 structural protein""" ; rdfs:label "6K" ; rdfs:seeAlso "Protegen ID: 775; NCBI Protein GI: 29611993; NCBITaxon: 11039" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010841, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011308 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In this study, Cp23 antigen was investigated as a vaccine candidate using the DNA vaccine model in adult interleukin-12 (IL-12) knockout (KO) mice, which are susceptible to C. parvum infection. Cp23-DNA vaccination induced a 50-60% reduction in oocysts shedding, indicating a partial protection against C. parvum infection in IL-12 KO mice [PubMed: 17487508]." ; rdfs:label "CP23" ; rdfs:seeAlso "Protegen ID: 776; NCBI Protein GI: 88659549; NCBITaxon: 5807" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010842, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011309 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Preparturient cows were immunized three times over a six-week period with recombinant plasmid DNA encoding the Cryptosporidium parvum CP15/60 antigen by injecting the DNA in the mammary gland. Colostrum from these cows contained Ab specific for C. parvum sporozoites and oocysts as indicated by immunofluorescence Ab (IFA) staining. Mice receiving immune colostrum showed partial protection (about 50% reduction) against intestinal C. parvum development compared to mice receiving control colostrum. This protection was evident at a challenge dose of 10^3 C. parvum oocysts per mouse [PubMed: 10392628]." ; rdfs:label "CP15/60" ; rdfs:seeAlso "Protegen ID: 777; NCBI Nucleotide GI: 170676501; NCBI Protein GI: 170676502; NCBI Protein Accession: ACB30404.1; NCBITaxon: 5807" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010842, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011310 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A subunit vaccine formulation containing only recombinant, soluble, attachment glycoprotein G from HeV (sG(HeV)) and CpG adjuvant was evaluated as a potential NiV vaccine in the cat model. Upon oronasal challenge with NiV (50,000TCID50), all vaccinated cats were protected from disease although virus was detected on day 21 post-challenge in one animal [PubMed: 18556094]." ; rdfs:label "G glycoprotein from Hendra virus" ; rdfs:seeAlso "Protegen ID: 779; NCBI Gene GI: 1446471; NCBI Protein GI: 29468607; NCBI Protein Accession: NP_047112; NCBITaxon: 63330" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010843, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011311 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A recombinant baculovirus encoding a dengue (DEN)-2 virus envelope glycoprotein truncated of 102 amino acids (aa) at its C-terminus (D2EA102) was constructed. Both intracellular and extracellular D2EA102 induced neutralizing antibodies in mice and were thus immunogenic. Sixty eight percent (P < 0.001) of mice vaccinated with 5 gg of extracellular D2EA102 protein were protected against lethal challenge [PubMed: 7826210]." ; rdfs:label "E protein from Dengue virus" ; rdfs:seeAlso "Protegen ID: 780; NCBI Protein GI: 202078796; NCBITaxon: 11060" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010844, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011312 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The protective efficacy and immune responses of mice intramuscularly injected with plasmid encoding DEN-2 non-structural protein 1 (NS1) was evaluated. Intravenously challenged by lethal DEN-2, mice vaccinated with NS1-DNA exhibited a delay onset of paralysis, a marked decrease of morbidity, and a significant enhancement of survival [PubMed: 12922127]." ; rdfs:label "NS1 from Dengue virus" ; rdfs:seeAlso "Protegen ID: 781; NCBI Protein GI: 288848; NCBITaxon: 11060" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010844, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011313 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Hamsters were immunized subcutaneously with either 107 PFU of VV-NiV.G or VV-NiV.F expressing the G and F glycoproteins, respectively, or with the two combined. When the VV-NiV.G-vaccinated animals were challenged with Nipah virus 3 months after the last immunization (1,000 PFU/animal intraperitoneally), there was complete protection against mortality [PubMed: 14694115]." ; rdfs:label "G glycoprotein from Nipah virus" ; rdfs:seeAlso "Protegen ID: 782; NCBI Gene GI: 920955; NCBI Protein GI: 13559814; NCBI Protein Accession: NP_112027; NCBITaxon: 121791" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010845, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011314 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Hamsters were immunized subcutaneously with either 10^7 PFU of VV-NiV.G or VV-NiV.F expressing the G and F glycoproteins, respectively, or with the two combined. When the VV-NiV.F-vaccinated animals were challenged with Nipah virus 3 months after the last immunization (1,000 PFU/animal intraperitoneally), there was complete protection against mortality [PubMed: 14694115]." ; rdfs:label "F fusion protein from Nipah virus" ; rdfs:seeAlso "Protegen ID: 783; NCBI Nucleotide GI: 8164021; NCBI Protein GI: 8164022; NCBI Protein Accession: AAF73956.1; NCBITaxon: 121791" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010845, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011315 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A recombinant vaccinia virus that expressed the pre-M protein of Dengue 4 virus was constructed. Mice immunized with the recombinant virus were protected against subsequent dengue 4 encephalitis challenge [PubMed: 1926792]." ; rdfs:label "PrM from Dengue Virus" ; rdfs:seeAlso "Protegen ID: 784; NCBI Protein GI: 18308086; NCBITaxon: 11070" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010844, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011316 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A recombinant vaccinia virus that expressed the M protein of Dengue 4 virus was constructed. Mice immunized with the recombinant virus were protected against subsequent dengue 4 encephalitis challenge [PubMed: 1926792]." ; rdfs:label "M protein" ; rdfs:seeAlso "Protegen ID: 785; NCBI Protein GI: 73671170; NCBITaxon: 11070" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010844, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011317 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Guinea pigs immunized with different doses of the SPA appear to be protected against challenge with live organisms as compared with nonimmunized controls [PubMed: 2122457]." ; rdfs:label "SpaP" ; rdfs:seeAlso "Protegen ID: 786; NCBI Protein GI: 152498; NCBITaxon: 782" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010846, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011318 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The glycoprotein (GP) and nucleocapsid (NC) genes of Rift Valley fever virus (RVFV) were expressed in different expression systems and were evaluated for their ability to protect mice from virulent challenge using a prime-boost regime. Mice vaccinated with a lumpy skin disease virus-vectored recombinant vaccine (rLSDV-RVFV) expressing the two RVFV glycoproteins (G1 and G2, expressed by the RVFV M Segment) developed neutralising antibodies and were fully protected when challenged, as were those vaccinated with a crude extract of truncated G2 glycoprotein (tG2) [PubMed: 16870311]." ; rdfs:label "RVFVsMgp1 M protein" ; rdfs:seeAlso "Protegen ID: 787; NCBI Gene GI: 956559; NCBI Protein GI: 27881464; NCBI Protein Accession: NP_777376; NCBITaxon: 11588" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010849, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011319 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunisation of mice with cDNA encoding the nucleocapsid protein induced strong humoral and lymphocyte proliferative immune responses. Even though complete protection was not achieved by genetic immunisation, four out of eight mice vaccinated with cDNA encoding the nucleocapsid protein displayed no clinical signs of infection after challenge. In contrast, all fourteen control animals displayed clinical manifestations of Rift Valley Fever after challenge [PubMed: 19149901]." ; rdfs:label "RVFVsSgp2 N protein" ; rdfs:seeAlso "Protegen ID: 788; NCBI Gene GI: 956562; NCBI Protein GI: 9632367; NCBI Protein Accession: NP_049344; NCBITaxon: 11588" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010849, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011320 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The receptor-binding domain (RBD) of SARS-CoV spike (S) protein is an important target in developing safe and effective SARS vaccines. A previous study has demonstrated that vaccination with adeno-associated virus encoding RBD (RBD-rAAV) induces high titer of neutralizing antibodies. The immune responses and protective effect of the immunization with RBD-rAAV prime/RBD-specific T cell peptide boost were assessed. Compared with the RBD-rAAV prime/boost vaccination, RBD-rAAV prime/RBD-peptide (RBD-Pep) boost induced similar levels of Th1 and neutralizing antibody responses that protected the vaccinated mice from subsequent SARS-CoV challenge, but stronger Th2 and CTL responses. No significant immune responses and protective effects were detected in mice vaccinated with RBD-Pep or blank AAV alone [PubMed: 18289745]." ; rdfs:label "S protein of SARS-CoV" ; rdfs:seeAlso "Protegen ID: 789; NCBI Gene GI: 1489668; NCBI Protein GI: 29836496; NCBI Protein Accession: NP_828851; NCBITaxon: 694009" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010850, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011321 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice actively immunized using a recombinant V antigen (rVagHis, encoded by lcrV gene) of Y. enterocolitica were completely protected against challenge with both, Y. enterocolitica 0:8 and Y. pseudotuberculosis serotype III [PubMed: 10089162]." ; rdfs:label "LcrV" ; rdfs:seeAlso "Protegen ID: 790; NCBI Gene GI: 1449458; NCBI Protein GI: 32470278; NCBI Protein Accession: NP_863514; NCBITaxon: 630" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010851, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011322 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "80% of C3H/HeJ mice immunized with Eh29 administered in combination with a subclinical dose of whole cholera toxin, but not as an Eh29-CTxB fusion, showed no evidence of infection in tissue sections harvested following intracecal challenge with virulent E. histolytica trophozoites. These results suggest that Eh29 is capable of inducing protective anti-amoebic immune responses in mice following oral immunization and could be used in the development of oral vaccines against amoebiasis [PubMed: 20303954]." ; rdfs:label "GEh29" ; rdfs:seeAlso "Protegen ID: 791; NCBI Nucleotide GI: 399673; NCBI Protein GI: 399674; NCBI Protein Accession: CAA50324.1; NCBITaxon: 5759" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010852, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011323 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Study tested if vaccination with the E. histolytica Gal/GalNAc lectin could prevent cecal infection in a C3H mouse model of amebic colitis. Vaccination prevented intestinal infection with efficacies of 84 and 100% in the two native lectin trials and 91 and 34% in the two LecA trials. Results show for the first time that immunization with the Gal/GalNAc lectin can prevent intestinal amebiasis in mice [PubMed: 14741152]." ; rdfs:label "Gal/GalNAc lectin" ; rdfs:seeAlso "Protegen ID: 792; NCBI Gene GI: 3404842; NCBI Protein GI: 67469085; NCBI Protein Accession: XP_650534; NCBITaxon: 294381" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010852, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011324 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Report describes a recombinant fusion protein containing the serine-rich Entamoeba histolytica protein (SREHP), a protective antigen derived from virulent amebae, and a bacterially derived maltose-binding protein (MBP) from an attenuated strain of Salmonella typhimurium. Gerbils vaccinated with S typhimurium SREHP-MBP were protected against amebic liver abscess after challenge with E. histolytica, the most common extraintestinal complication of amebiasis [PubMed: 8613356]." ; rdfs:label "SREHP" ; rdfs:seeAlso "Protegen ID: 793; NCBI Gene GI: 3402462; NCBI Protein GI: 67463194; NCBI Protein Accession: XP_648254; NCBITaxon: 294381" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010852, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011325 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Groups of C57BL/6 mice (20 per group) vaccinated with rPep1 (1 mug per dose) plus adjuvant and challenged with an intranasal inoculum began to die at about 14 to 16 days but then showed significantly greater survival than the control mice [PubMed: 16369008]." ; rdfs:label "PEP1" ; rdfs:seeAlso "Protegen ID: 794; NCBI Protein GI: 73915320; NCBITaxon: 199306" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011326 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researcherse tested the ability of the galactose-specific adherence lectin of E. histolytica to elicit a protective immune response in conjunction with Freund's incomplete and complete adjuvants. Four independent trials demonstrated complete protection from amebic liver abscess formation in 67% of lectin-immunized gerbils. The gerbil antilectin antibodies were shown by Western immunoblotting to be directed to the heavy subunit (CEL-170/4) but not the light subunit of the lectin [PubMed: 1987067]." ; rdfs:label "CEL-170/4" ; rdfs:seeAlso "Protegen ID: 795; NCBI Protein GI: 401088; NCBITaxon: 5759" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010852, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011327 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "C57BL/6 mice immunized with rPlb showed a significant reduction of the fungal burden in their lungs at 90 days postchallenge compared to the control mice at 15 days [PubMed: 16369008]." ; rdfs:label "PLB" ; rdfs:seeAlso "Protegen ID: 796; NCBI Protein GI: 74486661; NCBITaxon: 199306" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011328 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "C57BL/6 mice immunized with rAMN1 showed a significant reduction of the fungal burden in their lungs at 90 days postchallenge compared to the control mice at 15 days [PubMed: 16369008]." ; rdfs:label "AMN1" ; rdfs:seeAlso "Protegen ID: 797; NCBI Protein GI: 76786276; NCBITaxon: 199306" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011329 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "ELI-Antigen 1 (ELI-Ag1) was tested for its protective capacity in BALB/c mice against intraperitoneal challenge with 2500 arthroconidia of this dimorphic fungus and was found to be highly protective [PubMed: 14505918]." ; rdfs:label "ELI-Ag1" ; rdfs:seeAlso "Protegen ID: 798; NCBI Protein GI: 37779128; NCBITaxon: 5501" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011330 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The GEL1 mRNA of C. posadasii was detected at the highest level during the endosporulation stage of the parasitic cycle, and the mature protein was immunolocalized to the surface of endospores. BALB/c or C57BL/6 mice were immunized subcutaneously with the bacterium-expressed recombinant protein (rGel1p) to evaluate its protective efficacy against a lethal challenge of C. posadasii by either the intraperitoneal or intranasal route. In both cases, rGel1p-immune mice infected with the pathogen showed a significant reduction in fungal burden and increased survival compared to nonimmune mice [PubMed: 12761077]." ; rdfs:label "GEL1" ; rdfs:seeAlso "Protegen ID: 799; NCBI Protein GI: 14582416; NCBITaxon: 199306" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011331 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant urease (rURE) of C. immitis was expressed in Escherichia coli and tested asa vaccine candidate in BALB/c mice. BALB/c mice immunized subcutaneously with rURE and subsequently challenged by the intraperitoneal (i.p.) route with a lethal inoculum of C. immitis arthroconidia demonstrated a significant reduction in the level of C. immitis infection compared to control animals [PubMed: 11292702]." ; rdfs:label "URE" ; rdfs:seeAlso "Protegen ID: 800; NCBI Protein GI: 73808050; NCBITaxon: 5501" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011332 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant Pmp1 was reactive with serum from individuals with both acute and protracted disease, and evoked protection in two murine models of infection with C. posadasii [PubMed: 16495561]." ; rdfs:label "Pmp1" ; rdfs:seeAlso "Protegen ID: 801; NCBI Protein GI: 78364922; NCBITaxon: 199306" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011333 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "C57BL6 mice were immunized with syngeneic, bone marrow-derived DCs (JAWS II cells) transfected with a cDNA encoding the protective Coccidioides-Ag2/proline-rich Ag (pra). The immunized mice were lethally challenged with C. posadasii through either an i.p. or intranasal route. Upon necropsy after 10 days of infection, fungal burden in lung and spleen of immunized mice was significantly reduced as compared with the control animals. The lung tissue homogenates of immunized animals showed higher levels of IFN-gamma. Histologically, lung tissues of immunized mice were in better condition than the control mice [PubMed: 16148136]." ; rdfs:label "Pra" ; rdfs:seeAlso "Protegen ID: 802; NCBI Protein GI: 42742528; NCBITaxon: 5501" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011334 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The microtubule-associate protein (MAP p15) was tested as a vaccine in mice, and tests showed that p15 (native or recombinant) generated up to 100% protection from an otherwise lethal challenge of a heterologous strain of Trypanosoma brucei [PubMed: 15161078]." ; rdfs:label "MAPP15" ; rdfs:seeAlso "Protegen ID: 803; NCBI Protein GI: 777767; NCBITaxon: 5691" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010854, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000182 ] . obo:VO_0011335 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination with poliovirus vector containing the gene for the B subunit of H. pylori urease provides significant prophylactic and strong therapeutic protection against H. pylori in mice [PubMed: 15603891]." ; rdfs:label "UreB" ; rdfs:seeAlso "Protegen ID: 804; NCBI Protein GI: 40737733; NCBITaxon: 210" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010855, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011336 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Researchers prepared an oral liposome-encapsulated recombinant Helicobacter pylori (Hp) heat shock protein 60 (Hsp60) vaccine and investigate its effect against Hp infection in mice. rHsp60 plus CT (choleratoxin), liposome-encapsulated rHsp60 and liposome-encapsulated rHsp60 plus CT had protective rates against Hp infection of 73.3%, 66.7% and 86.7%, respectively [PubMed: 15897126]." ; rdfs:label "Hsp60" ; rdfs:seeAlso "Protegen ID: 805; NCBI Protein GI: 397869; NCBITaxon: 210" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010855, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011337 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A study shows that vaccination of mice with HP-NAP (H. pylori NAP) induces protection against H. pylori challenge, and that the majority of infected patients produce antibodies specific for HP-NAP, suggesting an important role of this factor in immunity [PubMed: 10790422]." ; rdfs:label "NAP" ; rdfs:seeAlso "Protegen ID: 806; NCBI Protein GI: 8777456; NCBITaxon: 210" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010855, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011338 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "BALB-c mice immunized intramuscularly with a single dose (100 microg) of a plasmid DNA encoding the 5'-terminal region of the trans-sialidase (nTSA) gene of T. brucei brucei are able to produce IgG antibodies that bind to the bloodstream form of T. brucei-protein extract and recognize the recombinant nTSA protein, expressed in Escherichia coli. Furthermore, this DNA vaccination process was able to protect 60% of mice submitted to a challenge assay with the infective form of T. brucei brucei parasites [PubMed: 19582478]." ; rdfs:label "TSA from Trypanosoma brucei" ; rdfs:seeAlso "Protegen ID: 807; NCBI Protein GI: 62175539; NCBITaxon: 5691" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010854, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000182 ] . obo:VO_0011339 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant H. pylori catalase plus CT was used for immunization, and groups of mice were challenged with the Sydney strain of H. pylori. Immunization with recombinant catalase protected a significant proportion (9 of 10) of the mice from H. pylori challenge, indicating that this enzyme should be considered as a candidate for a future vaccine [PubMed: 9353048]." ; rdfs:label "Catalase" ; rdfs:seeAlso "Protegen ID: 808; NCBI Protein GI: 3128145; NCBITaxon: 210" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010855, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011340 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A study to examine the immunostimulatory properties of Leishmania infantum Hsp83 (83) to elicit humoral and cellular response against the Toxoplasma gondii Rop2 protein in an adjuvant-free vaccination system was conducted. Mice immunized with fusion Rop2-83 elicited a stronger humoral and cellular response in comparison to mice immunized with Rop2 alone, or a mix of LiHsp83 and Rop2. The fusion protein induced a Th1 type response, with predominance of specific IgG2a/IgG2c isotype and IFN-gamma secretions, whereas Rop2 alone or mixed with LiHsp83 produced a Th1/Th2 mixed response. Vaccination with fusion protein conferred a remarkable resistance against oral infection with ME49 cysts in C57BL/6 and C3H mice, in comparison to mice immunized with Rop2 alone or the protein mixture. Following lethal challenge, a significant survival rate was observed in Rop2-83 immunized Balb/c and C57BL/6 mice in comparison to control groups [PubMed: 16545504]." ; rdfs:label "Rop2" ; rdfs:seeAlso "Protegen ID: 809; NCBI Protein GI: 115299638; NCBITaxon: 5811" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010826, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000338 ] . obo:VO_0011341 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Treatment of the Helicobacter pylori vacuolating cytotoxin with very low concentrations of formaldehyde resulted in abrogation of toxic activity in both a HeLa cell vacuolation assay and an in vivo assay of gastric epithelial damage. Detoxification had only a minimal effect on the integrity of the oligomeric or monomeric structure. The toxoid retained the ability to bind to target cells and to induce high-titer neutralizing antibodies after immunization of rabbits. Furthermore, oral immunization of mice with the toxoid resulted in protection against infective challenge with mouse-adapted strains of H. pylori [PubMed: 9353041]." ; rdfs:label "VacA" ; rdfs:seeAlso "Protegen ID: 810; NCBI Protein GI: 50313203; NCBITaxon: 210" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010855, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011342 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The immunogenicity of a 48-kDa T-cell-reactive protein (TCRP) was investigated. Immunization of BALB/c and C3H/HeN mice with the rTCRP affords a modest but significant level of protection against an intraperitoneal challenge with C. immitis. It is suggested that the rTCRP may be able to contribute to a multicomponent vaccine designed to stimulate CMI response against the parasitic cycle of C. immitis." ; rdfs:label "TcrP" ; rdfs:seeAlso "Protegen ID: 811; NCBI Protein GI: 13508695; NCBITaxon: 5501" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010853, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011343 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Some of the S. sciureus monkeys immunized with MSP-3(212-380)-AS02 or GLURP(27-500)-alum were able to fully or partially control parasitaemia upon an experimental P. falciparum [Falciparum Uganda Palo Alto (FUP-SP) strain] blood-stage infection, and this protection was related to the prechallenge antibody titres induced. The data are indicative that MSP-3 and GLURP can induce protective immunity against an experimental P. falciparum infection using adjuvants that are acceptable for human use and this should trigger further studies with those new antigens [PubMed: 15049780]." ; rdfs:label "GLURP" ; rdfs:seeAlso "Protegen ID: 812; NCBI Gene GI: 810501; NCBI Protein GI: 124802897; NCBI Protein Accession: XP_001347628; NCBITaxon: 36329" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000242 ] . obo:VO_0011344 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Asian seabass vaccinated with the OMP38 (OmpU) DNA vaccine was challenged with pathogenic V. anguillarum by intramuscular injection. A relative percent survival (RPS) rate of 55.6% was recorded [PubMed: 17337208]." ; rdfs:label "OmpU" ; rdfs:seeAlso "Protegen ID: 813; NCBI Protein GI: 26513901; NCBITaxon: 55601" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010815, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0011345 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus DNA vaccine encoding PrM" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1067" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011146 ] . obo:VO_0011346 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "DeltaFTT0918" ; rdfs:seeAlso "VIOLIN Vaccine ID: 439" ; rdfs:subClassOf obo:VO_0000152 . obo:VO_0011347 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0000233 ; obo:IAO_0100001 obo:VO_0000431 ; a owl:Class ; rdfs:label "obsolete rLm/iglC" ; rdfs:seeAlso "VIOLIN Vaccine ID: 440" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0011348 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "5CVMB" ; rdfs:seeAlso "VIOLIN Vaccine ID: 438" ; rdfs:subClassOf obo:VO_0000053 . obo:VO_0011349 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. amazonensis DNA vaccine encoding WD protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1041" ; rdfs:subClassOf obo:VO_0012158, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011290 ] . obo:VO_0011350 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. infantum H1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1042" ; rdfs:subClassOf obo:VO_0012159, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011285 ] . obo:VO_0011351 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. infantum HASPB1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1043" ; rdfs:subClassOf obo:VO_0012159, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011286 ] . obo:VO_0011352 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus DNA vaccine pUJENS5" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1036" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011149 ] . obo:VO_0011353 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus DNA vaccine encoding E protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1037" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011146 ] . obo:VO_0011354 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. amazonensis DNA vaccine encoding GP46" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1038" ; rdfs:subClassOf obo:VO_0012158, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011292 ] . obo:VO_0011355 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. amazonensis M2 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1039" ; rdfs:subClassOf obo:VO_0012158, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011291 ] . obo:VO_0011356 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "A. pleuropneumoniae ApxIA protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 782" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011019 ] . obo:VO_0011357 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pertussis Cpn60 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 797" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011035 ] . obo:VO_0011359 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pertussis CyaA protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 799" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011031 ] . obo:VO_0011360 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "V. cholerae CTB DNA Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 800" ; rdfs:subClassOf obo:VO_0000763, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011270 ] . obo:VO_0011361 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pertussis PTx protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 801" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011039 ] . obo:VO_0011362 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. parvum DNA vaccine encoding CP23" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1050" ; rdfs:subClassOf obo:VO_0012160 . obo:VO_0011363 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:C7828795", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1051" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/343" ; obo:OGG_0000000006 "2064" ; obo:VO_0001818 "1051" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: ERBB2" ; rdfs:label "Cancer Her-2/neu Protein Subunit Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005484, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1612 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011364 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:17266027", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1052" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/315" ; obo:OGG_0000000006 "6528" ; obo:VO_0001818 "1052" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: SLC5A5" ; rdfs:label "Cancer DNA Vaccine MIDGE/hNIS encoding hNIS protein" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011365 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:19526360", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1053" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/318" ; obo:OGG_0000000006 "2315863" ; obo:VO_0001818 "1053" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: Survivin" ; rdfs:label "Cancer DNA Vaccine pSURV encoding Survivin" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011366 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:21448901", "PubMed:31980914", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1047" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/368" ; obo:OGG_0000000006 "1485" ; obo:VO_0001818 "1047" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: CTAG1B" ; rdfs:label "Cancer Subunit NY-ESO-1 Protein Vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011367 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1048" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/314" ; obo:OGG_0000000006 "13805" ; obo:VO_0001818 "1048" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: Eng" ; rdfs:label "Cancer DNA Vaccine encoding Endoglin Boosted with Recombinant Endoglin Protein" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011368 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:10678354", "PubMed:8363286", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1049" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/345" ; obo:OGG_0000000006 "14972" ; obo:VO_0001818 "1049" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: H2-K1" ; rdfs:label "Cancer recombinant vector vaccine encoding H-2Kb" ; rdfs:subClassOf obo:VO_0000484, obo:VO_0005427, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000636 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_0060058 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ] . obo:VO_0011369 obo:IAO_0000115 "An xenogenic DNA vaccine encoding human TEM8 carried by attenuated Salmonella typhimurium to help reduce tumor growth and suppress angiogenesis in the tumors." ; obo:IAO_0000117 "Allen Xiang", "Oliver He" ; obo:IAO_0000119 "PubMed:19609240", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1046" ; obo:VO_0001818 "1046" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:label "cancer DNA vaccine encoding TEM8" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0011370 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:10881691", "PubMed:19188665", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1064" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/319" ; obo:OGG_0000000006 "4072" ; obo:VO_0001818 "1064" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: EPCAM" ; rdfs:label "Cancer EPCAM protein vaccine" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005429, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_3571 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011371 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:19034678", "PubMed:32164575", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1066" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/371" ; obo:OGG_0000000006 "7422" ; obo:VO_0001818 "1066" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: VEGFA" ; rdfs:label "Cancer VEGFA protein vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005428, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_1319 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011372 obo:IAO_0000117 "Allen Xiang", "Oliver He" ; obo:IAO_0000119 "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1058" ; obo:VO_0001818 "1058" ; a owl:Class ; rdfs:label "cancer Retroviral vector vaccine encoding Cd40lg" ; rdfs:subClassOf obo:VO_0000177, [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000532 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ] . obo:VO_0011373 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:/7533183", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=1059" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/317" ; obo:OGG_0000000006 "12524" ; obo:VO_0001818 "1059" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: Cd86" ; rdfs:label "Cancer DNA Vaccine pLXSHDmB7-2 encoding Cd86" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000344 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011374 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Phleum pratense Allergy Phl p 12 Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1054" ; rdfs:subClassOf obo:VO_0001362, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011280 ] . obo:VO_0011375 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. bovis GST-12D3" ; rdfs:seeAlso "VIOLIN Vaccine ID: 791" ; rdfs:subClassOf obo:VO_0000925, [ a owl:Restriction ; owl:onProperty obo:VO_0000527 ; owl:someValuesFrom obo:VO_0011027 ] . obo:VO_0011377 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pertussis BrkA protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 796" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011036 ] . obo:VO_0011378 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine leukemia virus DNA vaccine encoding Env" ; rdfs:seeAlso "VIOLIN Vaccine ID: 825" ; rdfs:subClassOf obo:VO_0012161, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011051 ] . obo:VO_0011379 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine leukemia virus DNA vaccine encoding Tax" ; rdfs:seeAlso "VIOLIN Vaccine ID: 828" ; rdfs:subClassOf obo:VO_0012161, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011050 ] . obo:VO_0011380 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. abortus DNA vaccine encoding RplL and Omp16" ; rdfs:seeAlso "VIOLIN Vaccine ID: 831" ; rdfs:subClassOf obo:VO_0001225, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010908 ] . obo:VO_0011381 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 DNA vaccine AdCMVgD" ; rdfs:seeAlso "VIOLIN Vaccine ID: 821" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011041 ] . obo:VO_0011382 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 DNA vaccine AdCMVgC" ; rdfs:seeAlso "VIOLIN Vaccine ID: 823" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011043 ] . obo:VO_0011383 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 GPI protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 824" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011042 ] . obo:VO_0011384 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "A. pleuropneumoniae ApxIa and ApxIIa protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 784" ; rdfs:subClassOf obo:VO_0001130, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011020 ] . obo:VO_0011385 obo:IAO_0000117 "Rebecca Racz, Yongqun He", "ZX" ; oboInOwl:hasAlternativeId "VO:0002770" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "In the present study, the gene encoding the ApxII-activating protein, apxIIC, was insertionally inactivated on the chromosome of a serovar 7 strain, HS93. Pigs vaccinated with live HS93C-Ampr via the intranasal route were protected against a cross-serovar challenge with a virulent serovar 1 strain of A. pleuropneumoniae" ; rdfs:label "A. pleuropneumoniae HS93C-Ampr" ; rdfs:seeAlso "VIOLIN Vaccine ID: 786" ; rdfs:subClassOf obo:VO_0001130 . obo:VO_0011386 obo:IAO_0000117 "Rebecca Racz, Yongqun He", "ZX" ; oboInOwl:hasAlternativeId "VO:0002800" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "The aroA gene was inactivated by inserting a fragment expressing kanamycin resistance within the coding sequence and challenged in fish. The LD50 for unvaccinated fish was 71. In contrast, the LD50 was 1.8 x 104 in fish vaccinated once and 3 x 105 in fish vaccinated twice" ; rdfs:label "A. salmonicida live-attenuated vaccine encoding AroA" ; rdfs:seeAlso "VIOLIN Vaccine ID: 788" ; rdfs:subClassOf obo:VO_0000820, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011024 ] . obo:VO_0011387 obo:IAO_0000115 "An Ebola virus vaccine that is composed of VEE replicon particle (VRP) encoding Ebola virus NP protein." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:hasAlternativeId "VO:0000779" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NP-VRP" ; rdfs:seeAlso "VIOLIN Vaccine ID: 443" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010859 ] . obo:VO_0011388 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rickettsia rickettsii vaccine using M. vaccae expressing R. rickettsii OmpA Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1044" ; rdfs:subClassOf obo:VO_0000767, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011234 ] . obo:VO_0011389 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rickettsia DNA Vaccine encoding OmpB Protein boosted with Recombinant OmpB" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1045" ; rdfs:subClassOf obo:VO_0000767, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011235 ] . obo:VO_0011391 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pertussis DNA vaccine encoding Prn" ; rdfs:seeAlso "VIOLIN Vaccine ID: 808" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011033 ] . obo:VO_0011392 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Virus Vaccine rFPV/gI" ; rdfs:seeAlso "VIOLIN Vaccine ID: 993" ; rdfs:subClassOf obo:VO_0012162, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011165 ] . obo:VO_0011393 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's Disease Virus Vaccine rFPV/gB1" ; rdfs:seeAlso "VIOLIN Vaccine ID: 994" ; rdfs:subClassOf obo:VO_0012162, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011164 ] . obo:VO_0011394 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg Virus Nucleoprotein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 997" ; rdfs:subClassOf obo:VO_0012163, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011163 ] . obo:VO_0011395 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus E7 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 986" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011105 ] . obo:VO_0011396 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum Hsp90 Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 987" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011241 ] . obo:VO_0011397 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus L2 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 988" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011106 ] . obo:VO_0011398 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "IHNV DNA vaccine pIHNw-G" ; rdfs:seeAlso "VIOLIN Vaccine ID: 989" ; rdfs:subClassOf obo:VO_0012165, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011109 ] . obo:VO_0011399 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rift Valley Fever Virus DNA Vaccine encoding N Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 990" ; rdfs:subClassOf obo:VO_0012166, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011319 ] . obo:VO_0011400 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Puumala virus PUUVsSgp1 (NP) protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 949" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011088 ] . obo:VO_0011401 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Sin Nombre virus DNA vaccine encoding G1" ; rdfs:seeAlso "VIOLIN Vaccine ID: 950" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011086 ] . obo:VO_0011402 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Seoul virus vaccine rCAV-2-Gc" ; rdfs:seeAlso "VIOLIN Vaccine ID: 951" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011085 ] . obo:VO_0011403 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Topografov virus N protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 952" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011089 ] . obo:VO_0011404 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B virus DNA vaccine pVAX-PS" ; rdfs:seeAlso "VIOLIN Vaccine ID: 968" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011094 ] . obo:VO_0011405 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus type 2 DNA vaccine encoding ICP27" ; rdfs:seeAlso "VIOLIN Vaccine ID: 969" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011100 ] . obo:VO_0011406 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus type 2 DNA vaccine encoding GB" ; rdfs:seeAlso "VIOLIN Vaccine ID: 970" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011097 ] . obo:VO_0011407 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "NIpah Virus G and F Proteins Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 971" ; rdfs:subClassOf obo:VO_0012169, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011314 ] . obo:VO_0011408 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus type 1 DNA vaccine encoding GC" ; rdfs:seeAlso "VIOLIN Vaccine ID: 972" ; rdfs:subClassOf obo:VO_0000958, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011103 ] . obo:VO_0011409 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hendra virus G protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 963" ; rdfs:subClassOf obo:VO_0012170, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011109 ] . obo:VO_0011410 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA Vaccine encoding Ag85B Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 964" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011172 ] . obo:VO_0011411 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B virus DNA vaccine encoding HBVgp2 pre-S1/pre-S2/S" ; rdfs:seeAlso "VIOLIN Vaccine ID: 965" ; rdfs:subClassOf obo:VO_0000644, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011095 ] . obo:VO_0011412 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis Mtb72F protein subunit vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 967" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011173 ] . obo:VO_0011413 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pertussis DNA vaccine encoding TcfA" ; rdfs:seeAlso "VIOLIN Vaccine ID: 813" ; rdfs:subClassOf obo:VO_0000765 . obo:VO_0011414 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. histolytica CEL-170/4 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 918" ; rdfs:subClassOf obo:VO_0012171, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011326 ] . obo:VO_0011415 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum Subunit SE36 Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 919" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011210 ] . obo:VO_0011416 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. histolytica SREHP protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 920" ; rdfs:subClassOf obo:VO_0012171, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011324 ] . obo:VO_0011417 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli C3389 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 921" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010991 ] . obo:VO_0011418 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum Pfen Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 922" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011223 ] . obo:VO_0011419 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Mumps HN Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 973" ; rdfs:subClassOf obo:VO_0000656, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011171 ] . obo:VO_0011420 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus type 2 vaccine using phage displaying GG protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 974" ; rdfs:subClassOf obo:VO_0012168, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011102 ] . obo:VO_0011421 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus type 1 DNA vaccine encoding GD" ; rdfs:seeAlso "VIOLIN Vaccine ID: 975" ; rdfs:subClassOf obo:VO_0000958, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011098 ] . obo:VO_0011422 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles Virus vaccine VEE/SIN-H+F" ; rdfs:seeAlso "VIOLIN Vaccine ID: 976" ; rdfs:subClassOf obo:VO_0000654 . obo:VO_0011423 obo:IAO_0000117 "Rebecca Racz, Yongqun He", "YH, ZX" ; oboInOwl:hasAlternativeId "VO:0002975" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:comment "An HSV-1 gE (Us8) deletion strain, NS-gEnull, was used as a live attenuated vaccine. After HSV-1 challenge, latent virus was recovered by DRG explant cocultures from <10% of vaccinated mice compared with 100% of mock-vaccinated mice" ; rdfs:label "Herpes simplex virus type 1 DNA vaccine encoding GE" ; rdfs:seeAlso "VIOLIN Vaccine ID: 977" ; rdfs:subClassOf obo:VO_0000958, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011104 ] . obo:VO_0011424 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. pneumoniae DNA vaccine encoding PknD" ; rdfs:seeAlso "VIOLIN Vaccine ID: 887" ; rdfs:subClassOf obo:VO_0012173, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010894 ] . obo:VO_0011425 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. pneumoniae DNA vaccine encoding Ssb" ; rdfs:seeAlso "VIOLIN Vaccine ID: 888" ; rdfs:subClassOf obo:VO_0012173, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010896 ] . obo:VO_0011426 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. psittaci DNA vaccine pcDNA1/MOMP" ; rdfs:seeAlso "VIOLIN Vaccine ID: 889" ; rdfs:subClassOf obo:VO_0012174, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010924 ] . obo:VO_0011427 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Classical swine fever virus vaccine VAC-E0" ; rdfs:seeAlso "VIOLIN Vaccine ID: 890" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010898 ] . obo:VO_0011428 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine encoding GatC" ; rdfs:seeAlso "VIOLIN Vaccine ID: 878" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011057 ] . obo:VO_0011429 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine encoding OmlA" ; rdfs:seeAlso "VIOLIN Vaccine ID: 879" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011060 ] . obo:VO_0011430 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine encoding MOMP" ; rdfs:seeAlso "VIOLIN Vaccine ID: 880" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010881 ] . obo:VO_0011431 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine Pomp90A" ; rdfs:seeAlso "VIOLIN Vaccine ID: 881" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011058 ] . obo:VO_0011432 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. pneumoniae CopN protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 882" ; rdfs:subClassOf obo:VO_0012173, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010884 ] . obo:VO_0011433 obo:IAO_0000117 "Allen Xiang", "Oliver He" ; a owl:Class ; rdfs:label "prostate cancer DNA vaccine encoding prostatic acid phosphatase (PAP)" ; rdfs:subClassOf obo:VO_0000032, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000623 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ] . obo:VO_0011434 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. pneumoniae DNA vaccine encoding FabD" ; rdfs:seeAlso "VIOLIN Vaccine ID: 884" ; rdfs:subClassOf obo:VO_0012173, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010895 ] . obo:VO_0011435 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. pneumoniae LcrE protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 885" ; rdfs:subClassOf obo:VO_0012173, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010883 ] . obo:VO_0011436 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pseudomallei Subunit LolC Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 860" ; rdfs:subClassOf obo:VO_0012175, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010921 ] . obo:VO_0011437 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum RplF protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 861" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010892 ] . obo:VO_0011438 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pseudomallei Subunit PotF Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 862" ; rdfs:subClassOf obo:VO_0012175, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010922 ] . obo:VO_0011439 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. yoelii MSP1 and MSP4/5 Proteins Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 984" ; rdfs:subClassOf obo:VO_0002514, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011236 ] . obo:VO_0011440 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. falciparum MSP3 Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 985" ; rdfs:subClassOf obo:VO_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011220 ] . obo:VO_0011441 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lassa Virus Nucleoprotein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1035" ; rdfs:subClassOf obo:VO_0012177, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:VO_0011151 [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] ) ] ] . obo:VO_0011442 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli C4424 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 923" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010990 ] . obo:VO_0011443 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli Hma protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 924" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010984 ] . obo:VO_0011444 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli IreA protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 925" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010985 ] . obo:VO_0011445 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. coli IutA protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 926" ; rdfs:subClassOf obo:VO_0000628, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010986 ] . obo:VO_0011446 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "F. tularensis GroEL protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 928" ; rdfs:subClassOf obo:VO_0000152, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011075 ] . obo:VO_0011447 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "F. tularensis DNA vaccine rLm/iglC" ; rdfs:seeAlso "VIOLIN Vaccine ID: 929" ; rdfs:subClassOf obo:VO_0000152, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011072 ] . obo:VO_0011448 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tenella vaccine rBCG pMV361-Rho" ; rdfs:seeAlso "VIOLIN Vaccine ID: 912" ; rdfs:subClassOf obo:VO_0001137, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011064 ] . obo:VO_0011449 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tenella DNA vaccine pcDNA-TA4-IL-2" ; rdfs:seeAlso "VIOLIN Vaccine ID: 913" ; rdfs:subClassOf obo:VO_0001137, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011065 ] . obo:VO_0011450 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. histolytica Eh29 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 915" ; rdfs:subClassOf obo:VO_0012171, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011322 ] . obo:VO_0011451 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. histolytica Gal/GalNAc lectin protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 916" ; rdfs:subClassOf obo:VO_0012171, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011323 ] . obo:VO_0011452 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue Vaccine using Vaccinia Virus expressing prM Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 853" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011315 ] . obo:VO_0011453 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum MOMP protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 854" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010890 ] . obo:VO_0011454 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue DNA Vaccine encoding NS1 Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 855" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011312 ] . obo:VO_0011455 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue Vaccine using Vaccinia Virus expressing M Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 856" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011316 ] . obo:VO_0011456 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum PmpE/F-2 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 857" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010893 ] . obo:VO_0011457 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dengue Subunit E Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 858" ; rdfs:subClassOf obo:VO_0000725, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011311 ] . obo:VO_0011458 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum PmpG-1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 859" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010891 ] . obo:VO_0011459 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine distemper virus DNA vaccine encoding HA" ; rdfs:seeAlso "VIOLIN Vaccine ID: 847" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011052 ] . obo:VO_0011460 obo:IAO_0000115 "a Coccidioides vaccine that contains C. posadasii PMP1 protein" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. posadasii subunit PMP1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 848" ; rdfs:subClassOf obo:VO_0012179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011332 ] . obo:VO_0011461 obo:IAO_0000115 "a Coccidioides vaccine that contains C. posadasii DNA vaccine encoding PRA protein" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. posadasii DNA Vaccine encoding PRA protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 849" ; rdfs:subClassOf obo:VO_0012179, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011333 ] . obo:VO_0011462 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine parvovirus DNA vaccine pGT36VP1" ; rdfs:seeAlso "VIOLIN Vaccine ID: 850" ; rdfs:subClassOf obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011055 ] . obo:VO_0011463 obo:IAO_0000115 "a Coccidioides vaccine that contains C. immitis subunit URE protein" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. immitis subunit URE protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 851" ; rdfs:subClassOf obo:VO_0012179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011331 ] . obo:VO_0011464 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine parvovirus CPMV-PARVO1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 852" ; rdfs:subClassOf obo:VO_0012180, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011054 ] . obo:VO_0011465 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ebola virus DNA vaccine encoding ZEBOV GP and SEBOV GP" ; rdfs:seeAlso "VIOLIN Vaccine ID: 901" ; rdfs:subClassOf obo:VO_0000726, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010910 ] . obo:VO_0011466 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. flexneri Invaplex 24 Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 902" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010994 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010995 ] . obo:VO_0011467 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. maxima Gam82 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 903" ; rdfs:subClassOf obo:VO_0001125, [ a owl:Restriction ; owl:onProperty obo:VO_0000527 ; owl:someValuesFrom obo:VO_0011062 ] . obo:VO_0011468 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. flexneri Invaplex 50 Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 904" ; rdfs:subClassOf obo:VO_0000680, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010994 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010995 ] . obo:VO_0011469 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tenella DNA vaccine proIE" ; rdfs:seeAlso "VIOLIN Vaccine ID: 905" ; rdfs:subClassOf obo:VO_0001137, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011066 ] . obo:VO_0011470 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tenella GX3262 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 907" ; rdfs:subClassOf obo:VO_0001137, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011067 ] . obo:VO_0011471 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tenella DNA vaccine EtMIC2" ; rdfs:seeAlso "VIOLIN Vaccine ID: 909" ; rdfs:subClassOf obo:VO_0001137, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011063 ] . obo:VO_0011472 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "E. tenella DNA vaccine rBCG pMV261-Rho" ; rdfs:seeAlso "VIOLIN Vaccine ID: 910" ; rdfs:subClassOf obo:VO_0001137, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011064 ] . obo:VO_0011473 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vaxxitek HVT+IBD" ; rdfs:seeAlso "VIOLIN Vaccine ID: 397" ; rdfs:subClassOf obo:VO_0012162 . obo:VO_0011474 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle disease virus vaccine by Dow AgroSciences" ; rdfs:seeAlso "VIOLIN Vaccine ID: 398" ; rdfs:subClassOf obo:VO_0001222 . obo:VO_0011475 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Theileria parva vaccine by Centre for Ticks and Tickborne Disease, Malawi" ; rdfs:seeAlso "VIOLIN Vaccine ID: 427" ; rdfs:subClassOf obo:VO_0001061 . obo:VO_0011476 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Theileria annulata vaccine by Local veterinary institutes" ; rdfs:seeAlso "VIOLIN Vaccine ID: 428" ; rdfs:subClassOf obo:VO_0000909 . obo:VO_0011477 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori DNA vaccine encoding UreB" ; rdfs:seeAlso "VIOLIN Vaccine ID: 960" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011335 ] . obo:VO_0011478 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. tuberculosis DNA Vaccine APADNA priming and APAMVA boosting" ; rdfs:seeAlso "VIOLIN Vaccine ID: 961" ; rdfs:subClassOf obo:VO_0000077, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011175 ] . obo:VO_0011479 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori VacA protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 962" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011341 ] . obo:VO_0011480 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Human papillomavirus DNA vaccine pNGVL4a-E6/opt" ; rdfs:seeAlso "VIOLIN Vaccine ID: 981" ; rdfs:subClassOf obo:VO_0000667, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011107 ] . obo:VO_0011481 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "PCV2 DNA Vaccine encoding ORF2 Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 982" ; rdfs:subClassOf obo:VO_0001524, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011243 ] . obo:VO_0011482 obo:IAO_0000115 "A multivalent vaccine against tetanus, diphtheria, and poliomyelitis." ; obo:IAO_0000117 "YH, ZX, NF" ; obo:IAO_0000118 "Tetanus and Diphtheria Toxoids Adsorbed and Inactivated Poliomyelitis Vaccine" ; obo:IAO_0000119 "WEB: https://www.vaccineshoppecanada.com/document.cfm?file=td_polio_adsorbed_e.pdf" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Td Polio Adsorbed" ; rdfs:seeAlso "ATC Code: J07CA01", "VIOLIN Vaccine ID: 630; VIOLIN Vaccine ID: 629; VIOLIN Vaccine ID: 628" ; rdfs:subClassOf obo:VO_0000586, obo:VO_0000640, obo:VO_0000664, obo:VO_0000735, obo:VO_0003547, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1513 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1717 ], [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:NCBITaxon_12080 obo:NCBITaxon_12083 obo:NCBITaxon_12086 ) ] ] . obo:VO_0011483 obo:IAO_0000117 "Allen Xiang", "Oliver He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0011482 ; a owl:Class ; rdfs:comment "This term is obsolete since there is another term with the same name." ; rdfs:label "obsolete Td Polio Adsorbed" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0011484 obo:IAO_0000117 "Allen Xiang", "Oliver He" ; obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:VO_0011482 ; a owl:Class ; rdfs:comment "This term is obsolete since there is another term with the same name." ; rdfs:label "obsolete Td Polio Adsorbed" ; rdfs:subClassOf owl:Thing ; owl:deprecated true . obo:VO_0011485 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. jejuni FspA1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 841" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011047 ] . obo:VO_0011486 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS Subunit Spike Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 842" ; rdfs:subClassOf obo:VO_0012183, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011320 ] . obo:VO_0011487 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. jejuni FspA2 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 843" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011049 ] . obo:VO_0011488 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. jejuni DNA vaccine pcDNA3.1(+)-peblA" ; rdfs:seeAlso "VIOLIN Vaccine ID: 844" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011045 ] . obo:VO_0011489 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Canine distemper virus DNA vaccine encoding F and HA" ; rdfs:seeAlso "VIOLIN Vaccine ID: 845" ; rdfs:subClassOf obo:VO_0012178, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011053 ] . obo:VO_0011490 obo:IAO_0000115 "a Coccidioides vaccine that contains C. posadasii subunit GEL1 protein" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. posadasii subunit GEL1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 846" ; rdfs:subClassOf obo:VO_0012179, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011330 ] . obo:VO_0011491 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. brucei DNA Vaccine encoding TSA protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 836" ; rdfs:subClassOf obo:VO_0012184, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011338 ] . obo:VO_0011492 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. brucei Subunit p15 Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 837" ; rdfs:subClassOf obo:VO_0012184, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011334 ] . obo:VO_0011493 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. jejuni MBP-FlaA protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 838" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011046 ] . obo:VO_0011494 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. parva Subunit p67 Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 839" ; rdfs:subClassOf obo:VO_0001061, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011183 ] . obo:VO_0011495 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. jejuni FlaC protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 840" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011048 ] . obo:VO_0011498 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pertussis FhaB and 69 kDa OMP protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 805" ; rdfs:subClassOf obo:VO_0000765, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011030 ] . obo:VO_0011499 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. influenzae Hap protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 936" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010916 ] . obo:VO_0011500 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus DNA vaccine encoding NS1 (pUSK-NS1)" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1033" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011147 ] . obo:VO_0011501 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus DNA vaccine pUJENS3" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1034" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011148 ] . obo:VO_0011502 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. parvum DNA vaccine encoding CP15/60" ; rdfs:seeAlso "VIOLIN Vaccine ID: 900" ; rdfs:subClassOf obo:VO_0012160, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011309 ] . obo:VO_0011503 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Y. enterocolititica Subunit V Antigen Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 896" ; rdfs:subClassOf obo:VO_0012186, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011321 ] . obo:VO_0011504 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. botulinum FHc protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 897" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010901 ] . obo:VO_0011505 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "WEEV DNA Vaccine encoding 6K-E1 Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 898" ; rdfs:subClassOf obo:VO_0012188, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011306 ] . obo:VO_0011506 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "WEEV Subunit E2 Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 899" ; rdfs:subClassOf obo:VO_0012188, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010897 ] . obo:VO_0011507 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:C5187854", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=891" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/367" ; obo:OGG_0000000006 "7015" ; obo:VO_0001818 "891" ; obo:VO_0005500 "Clinical trial" ; a owl:Class ; rdfs:comment "Gene name: TERT" ; rdfs:label "Cancer Subunit GV1001 Protein Vaccine" ; rdfs:subClassOf obo:VO_0000534, obo:VO_0005425, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000887 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_10283 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011508 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Classical swine fever virus vaccine VAC-E2" ; rdfs:seeAlso "VIOLIN Vaccine ID: 892" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010897 ] . obo:VO_0011509 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Classical swine fever virus E1 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 893" ; rdfs:subClassOf obo:VO_0001012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010899 ] . obo:VO_0011510 obo:IAO_0000117 "Eliyas Asfaw", "Ibrahim Seleznev", "Jie Zheng", "Oliver He " ; obo:IAO_0000119 "PubMed:wler=tru", "VIOLIN: https://violinet.org/canvaxkb/vaccine_detail.php?c_vaccine_id=894" ; obo:IAO_0000233 "https://github.com/vaccineontology/VO/issues/366" ; obo:OGG_0000000006 "1084" ; obo:VO_0001818 "894" ; obo:VO_0005500 "Research" ; a owl:Class ; rdfs:comment "Gene name: CEACAM3" ; rdfs:label "Cancer Subunit DC (Tat-CEA) vaccine" ; rdfs:subClassOf obo:VO_0000177, obo:VO_0000534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000624 ], [ a owl:Restriction ; owl:onProperty obo:VO_0000547 ; owl:someValuesFrom obo:VO_0000340 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001011 ; owl:someValuesFrom obo:DOID_162 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_10090 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ] . obo:VO_0011511 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. botulinum DNA vaccine pSCARSBHc" ; rdfs:seeAlso "VIOLIN Vaccine ID: 895" ; rdfs:subClassOf obo:VO_0012187, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010904 ] . obo:VO_0011512 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Dobrava-Belgrade virus S nucleocapsid protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 954" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010960 ] . obo:VO_0011513 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori catalase protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 955" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011339 ] . obo:VO_0011514 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. pylori NAP protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 958" ; rdfs:subClassOf obo:VO_0012181, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011337 ] . obo:VO_0011515 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "M. gallisepticum TM-1 Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 959" ; rdfs:subClassOf obo:VO_0000949, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011178 ] . obo:VO_0011516 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Japanese encephalitis virus vaccine BV-G-E" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1027" ; rdfs:subClassOf obo:VO_0000665, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011145 ] . obo:VO_0011517 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. annulata Subunit SPAG-1 Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 873" ; rdfs:subClassOf obo:VO_0000909, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011187 ] . obo:VO_0011518 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine encoding DnaK" ; rdfs:seeAlso "VIOLIN Vaccine ID: 874" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010882 ] . obo:VO_0011519 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine encoding DnaX" ; rdfs:seeAlso "VIOLIN Vaccine ID: 875" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011056 ] . obo:VO_0011520 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine encoding GatA/GatB" ; rdfs:seeAlso "VIOLIN Vaccine ID: 876" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010879 ] . obo:VO_0011521 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii Subunit Rop2-Hsp83 Fusion Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 866" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011340 ] . obo:VO_0011522 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum DNA vaccine encoding TC0757" ; rdfs:seeAlso "VIOLIN Vaccine ID: 867" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010886 ] . obo:VO_0011523 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA vaccine pcDNA3-MIC3" ; rdfs:seeAlso "VIOLIN Vaccine ID: 868" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011174 ] . obo:VO_0011524 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum DNA vaccine encoding TC0767/768" ; rdfs:seeAlso "VIOLIN Vaccine ID: 869" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010888 ] . obo:VO_0011525 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "T. gondii DNA Vaccine encoding SAG1 Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 870" ; rdfs:subClassOf obo:VO_0000994, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011000 ] . obo:VO_0011526 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine encoding CAB049" ; rdfs:seeAlso "VIOLIN Vaccine ID: 871" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011059 ] . obo:VO_0011527 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. abortus DNA vaccine encoding CAB613" ; rdfs:seeAlso "VIOLIN Vaccine ID: 872" ; rdfs:subClassOf obo:VO_0001085, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011061 ] . obo:VO_0011528 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infleunza virus DNA vaccine encoding NP from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1023" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0011529 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding NP from Influenza A virus (A/chicken/Hubei/489/2004(H5N1))" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1024" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0011530 obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000119 "http://www.violinet.org/vaxquery/vaccine_detail.php?c_vaccine_id=1025" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani DNA vaccine encoding KMP-11" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1025" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011157 ] . obo:VO_0011531 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus NP protein vaccine (Influenza A virus (A/nt/60/1968(H3N2)))" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1026" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0011532 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani gp63 Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1022" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011158 ] . obo:VO_0011533 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum DNA vaccine encoding TC0439" ; rdfs:seeAlso "VIOLIN Vaccine ID: 864" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010887 ] . obo:VO_0011534 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. muridarum DNA vaccine encoding TC0512" ; rdfs:seeAlso "VIOLIN Vaccine ID: 865" ; rdfs:subClassOf obo:VO_0012176, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0010885 ] . obo:VO_0011535 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles Virus Vaccine VVN" ; rdfs:seeAlso "VIOLIN Vaccine ID: 978" ; rdfs:subClassOf obo:VO_0000654 . obo:VO_0011536 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles Virus Vaccine VVP" ; rdfs:seeAlso "VIOLIN Vaccine ID: 979" ; rdfs:subClassOf obo:VO_0000654 . obo:VO_0011537 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Measles Virus Vaccine VVM" ; rdfs:seeAlso "VIOLIN Vaccine ID: 980" ; rdfs:subClassOf obo:VO_0000654 . obo:VO_0011538 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "B. pseudomallei DNA vaccine encoding Flagellin Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 863" ; rdfs:subClassOf obo:VO_0012175, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011303 ] . obo:VO_0011539 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani ORFF Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1017" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011159 ] . obo:VO_0011540 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding NA from Influenza B virus (B/Ibaraki/2/85)" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1018" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0011541 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Influenza virus DNA vaccine encoding NA from Influenza A virus (A/chicken/Henan/12/2004(H5N1))" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1019" ; rdfs:subClassOf obo:VO_0000642 . obo:VO_0011542 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "L. donovani DNA Vaccine encoding NH36 Protein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 1020" ; rdfs:subClassOf obo:VO_0001142, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011161 ] . obo:VO_0011543 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Sin Nombre virus DNA vaccine encoding SNVsSgp1 (NP)" ; rdfs:seeAlso "VIOLIN Vaccine ID: 945" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011087 ] . obo:VO_0011544 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. equi Subunit EAG, FNZ and SFS Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 832" ; rdfs:subClassOf obo:VO_0000948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011211 ] . obo:VO_0011545 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "C. jejuni DNA vaccine pcDNA3.1(+)-cadF" ; rdfs:seeAlso "VIOLIN Vaccine ID: 833" ; rdfs:subClassOf obo:VO_0012182, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011044 ] . obo:VO_0011546 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "S. equi Subunit CNE Protein Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 834" ; rdfs:subClassOf obo:VO_0000948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011213 ] . obo:VO_0011548 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "F. tularensis DNA vaccine pTUL4-15" ; rdfs:seeAlso "VIOLIN Vaccine ID: 930" ; rdfs:subClassOf obo:VO_0000152, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011076 ] . obo:VO_0011549 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "P. berghei CS protein subunit vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 931" ; rdfs:subClassOf obo:VO_0002513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011217 ] . obo:VO_0011550 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "G. duodenalis DNA vaccine encoding CWP2" ; rdfs:seeAlso "VIOLIN Vaccine ID: 932" ; rdfs:subClassOf obo:VO_0001083, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011080 ] . obo:VO_0011551 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. influenzae D15 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 933" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011083 ] . obo:VO_0011552 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Newcastle Disease Virus HN Glycoprotein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 934" ; rdfs:subClassOf obo:VO_0001222, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011209 ] . obo:VO_0011553 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies DNA Vaccine encoding Rabies virus Glycoprotein" ; rdfs:seeAlso "VIOLIN Vaccine ID: 816" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011231 ] . obo:VO_0011554 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 DNA vaccine tgD-VP22" ; rdfs:seeAlso "VIOLIN Vaccine ID: 817" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011040 ] . obo:VO_0011555 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rabies vaccine rVac-N" ; rdfs:seeAlso "VIOLIN Vaccine ID: 818" ; rdfs:subClassOf obo:VO_0000650, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011232 ] . obo:VO_0011556 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Vivotif L" ; rdfs:seeAlso "VIOLIN Vaccine ID: 645" ; rdfs:subClassOf obo:VO_0000768 . obo:VO_0011557 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Bovine herpesvirus 1 DNA vaccine pRSV-gC" ; rdfs:seeAlso "VIOLIN Vaccine ID: 815" ; rdfs:subClassOf obo:VO_0000987, obo:VO_0001482, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011043 ] . obo:VO_0011558 obo:IAO_0000117 "Kallan Roan, Oliver He, OT, ZX" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/845529", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm179132.htm" ; obo:VO_0003099 "IXIARO" ; obo:VO_0003158 "Japanese Encephalitis Vaccine, Inactivated, Adsorbed" ; obo:VO_0003160 "For the prevention of disease caused by Japanese encephalitis virus in persons 2 months of age and older." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM142569.pdf" ; obo:VO_0003162 "BL 125280" ; obo:VO_0003198 "845529" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Ixiaro" ; rdfs:seeAlso "CVX: 134", "VIOLIN Vaccine ID: 741" ; rdfs:subClassOf obo:VO_0000665, obo:VO_0000712, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003949 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000086 ; owl:someValuesFrom obo:VO_0000211 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000864 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0003076 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0011559 obo:IAO_0000117 "Kallan Roan, Oliver He, ZX" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/661026", "https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm186957.htm" ; obo:VO_0003099 "Cervarix" ; obo:VO_0003158 "Human Papillomavirus Bivalent (Types 16 and 18) Vaccine, Recombinant" ; obo:VO_0003160 "Prevention of cervical cancer, cervical intraepithelial neoplasia (CIN) grade 2 or worse and adenocarcinoma in situ, and cervical intraepithelial neoplasia (CIN) grade 1, caused by oncogenic human papillomavirus (HPV) types 16 and 18, in females9 through 25 years of age." ; obo:VO_0003161 "https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM186981.pdf" ; obo:VO_0003162 "BL 125259" ; obo:VO_0003198 "661026" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Cervarix" ; rdfs:seeAlso "CVX: 118", "VIOLIN Vaccine ID: 740" ; rdfs:subClassOf obo:VO_0000667, obo:VO_0001485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003940 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003941 ], [ a owl:Restriction ; owl:onProperty obo:OBI_0000295 ; owl:someValuesFrom obo:VO_0001187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000812 ], [ a owl:Restriction ; owl:onProperty obo:VO_0001243 ; owl:someValuesFrom obo:NCBITaxon_9606 ], [ a owl:Restriction ; owl:hasValue obo:VO_0000690 ; owl:onProperty obo:OBI_0000304 ] . obo:VO_0011561 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Andes virus vaccine using adenovirus viral vector expressing ANDV NP" ; rdfs:seeAlso "VIOLIN Vaccine ID: 943" ; rdfs:subClassOf obo:VO_0012167, [ a owl:Restriction ; owl:onProperty obo:RO_0002292 ; owl:someValuesFrom obo:VO_0011092 ] . obo:VO_0011562 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "H. influenzae Omp26 protein vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 938" ; rdfs:subClassOf obo:VO_0012185, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0010918 ] . obo:VO_0011563 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. caninum NcMIC1 Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 939" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011200 ] . obo:VO_0011564 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. caninum NcMAG1 Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 941" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011189 ] . obo:VO_0011565 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "N. caninum NcDG2 Protein Subunit Vaccine" ; rdfs:seeAlso "VIOLIN Vaccine ID: 942" ; rdfs:subClassOf obo:VO_0001065, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0011205 ] . obo:VO_0012158 obo:IAO_0000115 "A vaccine that protects against Leishmania amazonensis." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Leishmania amazonensis" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leishmania amazonensis vaccine" ; rdfs:subClassOf obo:VO_0000762, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5659 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5659 ] . obo:VO_0012159 obo:IAO_0000115 "A vaccine that protects against Leishmania infantum." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Leishmania infantum" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Leishmania infantum vaccine" ; rdfs:subClassOf obo:VO_0000762, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5671 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000762 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5671 ] ) ] . obo:VO_0012160 obo:IAO_0000115 "A vaccine that protects against Cryptosporidium parvum." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Cryptosporidium parvum" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Cryptosporidium parvum vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5807 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5807 ] . obo:VO_0012161 obo:IAO_0000115 "A vaccine that protects against Bovine Leukemia virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "bovine leukemia virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "bovine leukemia virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11901 ] . obo:VO_0012162 obo:IAO_0000115 "A vaccine that protects against Marek's disease virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Marek's; disease virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marek's disease virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10390 ] . obo:VO_0012163 obo:IAO_0000115 "A vaccine that protects against Marburg Virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Marburg Virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Marburg Virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_186537 ] . obo:VO_0012165 obo:IAO_0000115 "A vaccine that protects against Infectious Hematopoietic Necrosis Virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Infectious Hematopoietic Necrosis Virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Infectious Hematopoietic Necrosis Virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11290 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11290 ] ) ] . obo:VO_0012166 obo:IAO_0000115 "A vaccine that protects against Rift Valley Fever virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Rift Valley Fever virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Rift Valley Fever virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11588 ] . obo:VO_0012167 obo:IAO_0000115 "A vaccine that protects against Hantavirus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Hantavirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hantavirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1980442 ] . obo:VO_0012168 obo:IAO_0000115 "A vaccine that protects against Herpes simplex virus type 1 and 2." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Herpes simplex virus type 1 and 2" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Herpes simplex virus type 1 and 2 vaccine" ; rdfs:subClassOf obo:VO_0000727, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10310 ] . obo:VO_0012169 obo:IAO_0000115 "A vaccine that protects against Nipah virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Nipah virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Nipah virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052225 ] . obo:VO_0012170 obo:IAO_0000115 "A vaccine that protects against Hendra virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Hendra virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hendra virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052223 ] . obo:VO_0012171 obo:IAO_0000115 "A vaccine that protects against Entamoeba histolytica." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Entamoeba histolytica" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Entamoeba histolytica vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5759 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5759 ] . obo:VO_0012173 obo:IAO_0000115 "A Chlamydia vaccine that protects against Chlamydophila pneumoniae." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamydophila pneumoniae vaccine" ; rdfs:subClassOf obo:VO_0000573, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83558 ] . obo:VO_0012174 obo:IAO_0000115 "A Chlamydia bacterial vaccine against Chlamydophila psittaci infection" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamydophila psittaci vaccine" ; rdfs:subClassOf obo:VO_0000573, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83554 ] . obo:VO_0012175 obo:IAO_0000115 "A vaccine that protects against Burkholderia pseudomallei." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Burkholderia pseudomallei" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Burkholderia pseudomallei vaccine" ; rdfs:subClassOf obo:VO_0003532, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_28450 ] . obo:VO_0012176 obo:IAO_0000115 "A Chlamydia vaccine that protects against Chlamydia muridarum." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Chlamydia muridarum" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Chlamydia muridarum vaccine" ; rdfs:subClassOf obo:VO_0000573, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_83560 ] . obo:VO_0012177 obo:IAO_0000115 "A vaccine that protects against Lassa Fever Virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Lassa Fever Virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Lassa Fever Virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052310 ] . obo:VO_0012178 obo:IAO_0000115 "A vaccine that protects against Canine distemper virus." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "canine distemper virus vaccine" ; rdfs:subClassOf obo:VO_0003543, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_3052342 ] . obo:VO_0012179 obo:IAO_0000115 "A vaccine that protects against Coccidioides spp." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Coccidioides spp. vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Coccidioides vaccine" ; rdfs:subClassOf obo:VO_0000267, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5500 ] . obo:VO_0012180 obo:IAO_0000115 "A vaccine that protects against Canine parvovirus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Canine parvovirus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "canine parvovirus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_10788 ] . obo:VO_0012181 obo:IAO_0000115 "A vaccine that protects against Helicobacter pylori." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Helicobacter pylori" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Helicobacter pylori vaccine" ; rdfs:subClassOf obo:VO_0000165, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_210 ] . obo:VO_0012182 obo:IAO_0000115 "A Campylobacter vaccine that protects against Campylobacter jejuni." ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Campylobacter jejuni vaccine" ; rdfs:subClassOf obo:VO_0000568, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_197 ] . obo:VO_0012183 obo:IAO_0000115 "A vaccine that protects against SARS-CoV." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "SARS-CoV vaccine" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "SARS vaccine" ; rdfs:subClassOf obo:VO_0004897, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_694009 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_694009 ] . obo:VO_0012184 obo:IAO_0000115 "A vaccine that protects against Trypanosoma brucei." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Trypanosoma brucei" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Trypanosoma brucei vaccine" ; rdfs:subClassOf obo:VO_0000417, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5691 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_5691 ] . obo:VO_0012185 obo:IAO_0000115 "A vaccine that protects against Haemophilus influenzae." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Haemophilus influenzae" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae vaccine" ; rdfs:subClassOf obo:VO_0000661, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_727 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000661 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_727 ] ) ] . obo:VO_0012186 obo:IAO_0000115 "A vaccine that protects against Yersinia enterocolitica." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Yersinia enterocolitica" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Yersinia enterocolitica vaccine" ; rdfs:subClassOf obo:VO_0000601, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_150052 ] . obo:VO_0012187 obo:IAO_0000115 "A vaccine that protects against Clostridium botulinum ." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Clostridium botulinum" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Clostridium botulinum vaccine" ; rdfs:subClassOf obo:VO_0000639, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_1491 ] . obo:VO_0012188 obo:IAO_0000115 "A vaccine that protects against Western equine encephalomyelitis virus." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Western equine encephalomyelitis virus" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Western equine encephalomyelitis virus vaccine" ; rdfs:subClassOf obo:VO_0000609, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11039 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:VO_0000609 [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11039 ] ) ] . obo:VO_0012190 obo:IAO_0000115 "A vaccine that protects against Tick-borne Encephalitis Virus (TBEV)." ; obo:IAO_0000117 "YH, ZX" ; obo:IAO_0000118 "Tick-borne Encephalitis Virus (TBEV)" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tick-borne Encephalitis Virus (TBEV) vaccine" ; rdfs:subClassOf obo:VO_0003546, [ a owl:Restriction ; owl:onProperty obo:VO_0003355 ; owl:someValuesFrom obo:NCBITaxon_11084 ] . obo:VO_0012212 obo:IAO_0000115 "A vaccine preparation that results in the generation of a Cancer vaccine" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:hasAlternativeId "VO:0001236" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "cancer vaccine preparation" ; rdfs:seeAlso "VIOLIN Pathogen ID: 99" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0000177 ] . obo:VO_0012213 obo:IAO_0000115 "A vaccine preparation that results in the generation of a Allergy vaccine" ; obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "vaccine preparation" ; a owl:Class ; rdfs:label "allergy vaccine preparation" ; rdfs:seeAlso "VIOLIN Pathogen ID: 114" ; rdfs:subClassOf obo:VO_0000590, [ a owl:Restriction ; owl:onProperty obo:OBI_0000299 ; owl:someValuesFrom obo:VO_0001362 ] . obo:VO_0012355 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Staphylococcus aureus protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0012356 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Streptococcus agalactiae protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0012357 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Streptococcus pyogenes protein" ; rdfs:subClassOf obo:VO_0010752 . obo:VO_0012358 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Treponema pallidum protein" ; rdfs:subClassOf obo:VO_0010751 . obo:VO_0012359 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "YopH from Y. pestis strain: CO92, biovar: Orientalis" ; rdfs:seeAlso "Protegen ID: 51; NCBI Gene GI: 1172712; NCBI Protein GI: 16082755; NCBI Protein Accession: NP_395201; NCBITaxon: 214092" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010759, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012360 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "The oprF gene was cloned into plasmid vector pVR1020, and the plasmid vaccines were delivered to mice by biolistic (gene gun) intradermal inoculation. Following the initial immunization and two consecutive boosts, each at 2-week intervals, protection was demonstrated in a mouse model of chronic pulmonary infection by P. aeruginosa. Eight days postchallenge, both lungs were removed and examined. A significant reduction in the presence of severe macroscopic lesions, as well as in the number of bacteria present in the lungs, was seen [PubMed: 11292786]." ; rdfs:label "OprF" ; rdfs:seeAlso "Protegen ID: 843; NCBI Gene GI: 878442; NCBI Protein GI: 15596974; NCBI Protein Accession: NP_250468; NCBITaxon: 208964" ; rdfs:subClassOf obo:VO_0012370, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012361 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Burned Pseudomonas aeruginosa-infected mice immunized against PcrV, a type III virulence system translocating protein, showed significantly enhanced survival compared to controls [PubMed: 11500471]." ; rdfs:label "PcrV" ; rdfs:seeAlso "Protegen ID: 844; NCBI Gene GI: 882997; NCBI Protein GI: 15596903; NCBI Protein Accession: NP_250397; NCBITaxon: 208964" ; rdfs:subClassOf obo:VO_0012370, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012362 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant OprI protein was used to immunize mice, and was found to be protective against a challenge with a four- to fivefold 50% lethal dose of P. aeruginosa [PubMed: 2114360]." ; rdfs:label "OprI" ; rdfs:seeAlso "Protegen ID: 845; NCBI Gene GI: 879851; NCBI Protein GI: 15598049; NCBI Protein Accession: NP_251543; NCBITaxon: 208964" ; rdfs:subClassOf obo:VO_0012370, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012363 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "AY243312" ; rdfs:seeAlso "Protegen ID: 68; NCBI Nucleotide GI: 29692106" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010764, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012364 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In mice, a primary vaccination with Ag85B-encoding plasmid DNA (DNA-85B) was protective against Mycobacterium tuberculosis (MTB) infection and associated with Ag85B-specific CD4+ T cells producing IFN-gamma and controlling intramacrophagic MTB growth [PubMed: 17250590]." ; rdfs:label "Ag85B from M. tuberculosis H37Rv" ; rdfs:seeAlso "Protegen ID: 118; NCBI Gene GI: 885785; NCBI Protein GI: 15609023; NCBI Protein Accession: NC_000962.2; NCBITaxon: 1773" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012365 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "znuA" ; rdfs:seeAlso "Protegen ID: 228; NCBI Gene GI: 3341411; NCBI Protein GI: 62317941; NCBI Protein Accession: YP_223794; NCBITaxon: 262698" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012366 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intravenous vaccination with recombinant bacteria carrying expression plasmid for MPB/MPT51 in BALB/c mice elicited significant protective responses, comparable to those evoked by a live Mycobacterium bovis BCG vaccine [PubMed: 15039321]." ; rdfs:label "FbpD" ; rdfs:seeAlso "Protegen ID: 814; NCBI Gene GI: 7562680; NCBI Protein GI: 224992215; NCBI Protein Accession: YP_002646905; NCBITaxon: 561275" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012367 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment """DNA vaccines encoding secreted proteins Ag85B and MPT64 protect mice from the tuberculosis H37Rv strain [PubMed: 15498274]. *Note* MPT64 in combination with Ag85B was protective, DNA vaccine of just MPT64 was mildly protective in mice.""" ; rdfs:label "MPT64" ; rdfs:seeAlso "Protegen ID: 815; NCBI Gene GI: 885925; NCBI Protein GI: 15609117; NCBI Protein Accession: NP_216496; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012368 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In a prophylactic vaccine model, immunization with the Mycobacterium tuberculosis protein ESAT-6 with LANAC adjuvant elicited significant protective immunity against aerosol challenge with virulent M. tuberculosis [PubMed: 16751377]." ; rdfs:label "ESAT-6" ; rdfs:seeAlso "Protegen ID: 816; NCBI Gene GI: 886209; NCBI Protein GI: 57117165; NCBI Protein Accession: YP_178023; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012369 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "DNA vaccines encoding KatG antigen fused to TPA signal sequences evoked a significant protective response in mice aerogenically challenged with low doses of Mycobacterium tuberculosis Erdman 17 to 21 days after the final immunization [PubMed: 10456931]." ; rdfs:label "KatG" ; rdfs:seeAlso "Protegen ID: 817; NCBI Gene GI: 885638; NCBI Protein GI: 15609045; NCBI Protein Accession: NP_216424; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012370 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice vaccinated with PstS-3 DNA demonstrated significant and sustained reduction in bacterial CFU numbers in spleen and lungs for 3 mo after M. tuberculosis challenge, as compared with CFU counts in mice vaccinated with control DNA [PubMed: 9916741]." ; rdfs:label "PstS3" ; rdfs:seeAlso "Protegen ID: 818; NCBI Gene GI: 885366; NCBI Protein GI: 57116798; NCBI Protein Accession: YP_177768; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012371 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A selection of previously identified protective Mycobacterium tuberculosis DNA vaccines were re-formulated as proteins and administered with a Th1-inducing adjuvant to help stimulate the relevant immune responses necessary for protection. One candidate (Rv1806-1807) induced protection in the guinea pig aerosol infection model 30 days post-challenge on the basis of reducing the bacterial burden of M. tuberculosis in the lungs [PubMed: 16520093]." ; rdfs:label "PE20" ; rdfs:seeAlso "Protegen ID: 819; NCBI Gene GI: 885537; NCBI Protein GI: 57116919; NCBI Protein Accession: YP_177843; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012372 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A selection of previously identified protective Mycobacterium tuberculosis DNA vaccines were re-formulated as proteins and administered with a Th1-inducing adjuvant to help stimulate the relevant immune responses necessary for protection. One candidate (Rv1806-1807) induced protection in the guinea pig aerosol infection model 30 days post-challenge on the basis of reducing the bacterial burden of M. tuberculosis in the lungs [PubMed: 16520093]." ; rdfs:label "PPE31" ; rdfs:seeAlso "Protegen ID: 820; NCBI Gene GI: 885072; NCBI Protein GI: 57116920; NCBI Protein Accession: YP_177653; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012373 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Purified preparations of HBHA were emulsified in a dimethyldioctadecylammonium bromide-monophosphoryl lipid A adjuvant and tested for the ability to reduce M. tuberculosis infection in the mouse aerosol challenge model for tuberculosis. The HBHA-containing vaccine gave a approximately 0.7-log reduction in CFU in both mouse lungs and spleens compared to adjuvant controls 28 days following challenge [PubMed: 15557600]." ; rdfs:label "HBHA" ; rdfs:seeAlso "Protegen ID: 821; NCBI Gene GI: 5211814; NCBI Protein GI: 148660242; NCBI Protein Accession: YP_001281765; NCBITaxon: 25177" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012374 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "immunization with the soluble recombinant rMTB41 protein plus adjuvant, a regimen known to generate primarily CD4+ T cells, resulted in induction of protection comparable to BCG in two well-established animal models of tuberculosis (mice and guinea pigs) [PubMed: 15917115]." ; rdfs:label "PPE14" ; rdfs:seeAlso "Protegen ID: 822; NCBI Gene GI: 885069; NCBI Protein GI: 57116795; NCBI Protein Accession: YP_177765; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012375 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "GAPDH (Gap) associated with murine IL-12 gene in a DNA vaccine formulation partially protected mice against experimental infection [PubMed: 12171297]." ; rdfs:label "Gap" ; rdfs:seeAlso "Protegen ID: 823; NCBI Gene GI: 3340207; NCBI Protein GI: 62290600; NCBI Protein Accession: YP_222393; NCBITaxon: 262698" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010758, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012376 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "rHtrA was found to be very immunogenic and partially protective in both the passive infant rat model of bacteremia and the active chinchilla model of otitis media [PubMed: 9488373]." ; rdfs:label "HtrA" ; rdfs:seeAlso "Protegen ID: 824; NCBI Protein GI: 2935168; NCBITaxon: 727" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012377 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Orogastric immunization of mice with recombinant H. pylori HspA proteins protected 80% of animals from a challenge dose of 10^4 Helicobacter felis bacteria [PubMed: 7604021]." ; rdfs:label "HspA" ; rdfs:seeAlso "Protegen ID: 825; NCBI Protein GI: 712830; NCBITaxon: 210" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010855, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012378 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Orogastric immunization of mice with recombinant H. pylori HspB proteins protected 70% of animals from a challenge dose of 10^4 Helicobacter felis bacteria [PubMed: 7604021]." ; rdfs:label "HspB from Helicobacter pylori" ; rdfs:seeAlso "Protegen ID: 826; NCBI Protein GI: 712831; NCBITaxon: 210" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010855, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012379 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice were immunised with the citrate synthase protein by intra-Peyer's patch immunisation. Pre-immunisation with the citrate synthase protein led to a 84-91% reduction in H. pylori infection compared to unimmunised controls [PubMed: 10378424]." ; rdfs:label "GltA" ; rdfs:seeAlso "Protegen ID: 827; NCBI Protein GI: 2493711; NCBITaxon: 210" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010855, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012380 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Recombinant TbpA protein was used in a mouse intraperitoneal-infection model to determine their ability to protect against meningococcal infection and to induce cross-reactive and bactericidal antibodies. TbpA was found to afford protection against meningococcal challenge when administered as the sole immunogen [PubMed: 11179327]." ; rdfs:label "TbpA" ; rdfs:seeAlso "Protegen ID: 833; NCBI Protein GI: 8926211; NCBITaxon: 487" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010778, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012381 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In chimpanzees (Pan troglodytes), the primates most closely related to humans and that share a similar susceptibility to P. falciparum liver-stage infection, immunization with LSA-3 induced protection against successive heterologous challenges with large numbers of P. falciparum sporozoites [PubMed: 11062538]." ; rdfs:label "LSA-3" ; rdfs:seeAlso "Protegen ID: 834; NCBI Gene GI: 812783; NCBI Protein GI: 124801463; NCBI Protein Accession: XP_001349701; NCBITaxon: 36329" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0015471, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:OPL_0000137 ] . obo:VO_0012382 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "1 of 3 Monkeys vaccinated with EBA-175 was protected from challenge of parasitized erythrocytes [PubMed: 11471569]." ; rdfs:label "eba-175" ; rdfs:seeAlso "Protegen ID: 835; NCBI Gene GI: 2654998; NCBI Protein GI: 296004911; NCBI Protein Accession: XP_001349207; NCBITaxon: 36329" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010771, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:OPL_0000242 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012383 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with rPhpA-79 protein adjuvanted with monophosphoryl lipid A (for subcutaneous immunization) or a mutant cholera toxin, CT-E29H (for intranasal immunization), protected CBA/N mice against death and bacteremia, as well as reduced nasopharyngeal colonization, following intranasal challenge with a heterologous pneumococcal strain [PubMed: 11349048]." ; rdfs:label "phpA-79" ; rdfs:seeAlso "Protegen ID: 836; NCBI Protein GI: 13447096; NCBITaxon: 32630" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012384 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with recombinant OspA protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958]." ; rdfs:label "OspA" ; rdfs:seeAlso "Protegen ID: 838; NCBI Gene GI: 1194357; NCBI Protein GI: 11496927; NCBI Protein Accession: NP_045688; NCBITaxon: 224326" ; rdfs:subClassOf obo:VO_0012368, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012385 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with recombinant OspB protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958]." ; rdfs:label "OspB" ; rdfs:seeAlso "Protegen ID: 839; NCBI Gene GI: 1194340; NCBI Protein GI: 11496910; NCBI Protein Accession: NP_045689; NCBITaxon: 224326" ; rdfs:subClassOf obo:VO_0012368, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012386 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with recombinant OspC protein were protected from challenge with Borrelia burgdorferi [PubMed: 8168958]." ; rdfs:label "OspC" ; rdfs:seeAlso "Protegen ID: 840; NCBI Gene GI: 1194415; NCBI Protein GI: 11497024; NCBI Protein Accession: NP_047005; NCBITaxon: 224326" ; rdfs:subClassOf obo:VO_0012368, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012387 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with recombinant DbpA protein are protected against challenge with Borrelia burgdorferi [PubMed: 11035759]." ; rdfs:label "DbpA" ; rdfs:seeAlso "Protegen ID: 841; NCBI Gene GI: 8319341; NCBI Protein GI: 256041910; NCBI Protein Accession: YP_003110629; NCBITaxon: 521009" ; rdfs:subClassOf obo:VO_0012368, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012388 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In an attempt to generate a subunit vaccine in this experimental disease model, eukaryotic plasmid DNA expression vectors containing genes encoding either the wild-type or modified forms of recombinant listeriolysin O (hly) were generated and used for genetic vaccination of naive mice. Results of these studies indicate that the intramuscular immunization of mice with specifically designed plasmid DNA constructs encoding recombinant forms of listeriolysin O (hly) stimulates peptide-specific CD8+ immune T cells that exhibit in vitro cytotoxic activity. More importantly, such immunization can provide protective immunity against a subsequent challenge with viable L. monocytogenes [PubMed: 10384131]." ; rdfs:label "Hly" ; rdfs:seeAlso "Protegen ID: 842; NCBI Gene GI: 987033; NCBI Protein GI: 16802248; NCBI Protein Accession: NP_463733; NCBITaxon: 169963" ; rdfs:subClassOf obo:VO_0012369, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012389 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice were immunized with a recombinant fragment of CNA protein, and were then challenged with the S. aureus clinical isolate strain Phillips. At 14 d after inoculation, mortality in the collagen adhesin-vaccinated group was only 13%, compared with 87% in the control antigen immunized group [PubMed: 9637697]." ; rdfs:label "CNA" ; rdfs:seeAlso "Protegen ID: 846; NCBI Nucleotide GI: 387879; NCBI Protein GI: 387880; NCBI Protein Accession: AAA20874.1; NCBITaxon: 1280" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012355, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012390 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with recombinant ClfA and challenged with S. aureus developed less-severe arthritis than did mice immunized with a control antigen [PubMed: 11740733]." ; rdfs:label "ClfA" ; rdfs:seeAlso "Protegen ID: 847; NCBI Gene GI: 5330438; NCBI Protein GI: 151220968; NCBI Protein Accession: YP_001331790; NCBITaxon: 426430" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012355, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012391 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "An internal region from the transpeptidase domain from the PBP2a (encoded by mecA) was cloned into a mammalian expression vector, to be used as DNA vaccine in a Murine model. After three sets of DNA vaccination, the immune response represented by antibodies against a fragment of PBP2a was evaluated by enzyme linked immunosorbent assay (ELISA), showing a significant antibody response. The antibacterial effect of the DNA vaccine was evaluated by intraperitoneal immunization and challenge with a sublethal dose of MRSA for 7 days in mice. After the challenge, the number of bacteria from kidneys from immunized and non-immunized mice were determined. Kidneys from immunized mice had 1000 times less on bacteria than the positive controls (non-immunized mice) [PubMed: 12744903]." ; rdfs:label "MecA" ; rdfs:seeAlso "Protegen ID: 848; NCBI Gene GI: 2861157; NCBI Protein GI: 49482291; NCBI Protein Accession: YP_039515; NCBITaxon: 282458" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012355, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012392 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice were immunized with fusion proteins encompassing the fibronectin-binding domain of a staphylococcal fibronectin-binding protein (FnBP-A). Vaccination of mice with recombinant FnBP resulted in significant protection against challenge with S. aureus [PubMed: 7975852]." ; rdfs:label "FnbA" ; rdfs:seeAlso "Protegen ID: 849; NCBI Protein GI: 120457; NCBITaxon: 93061" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012355, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012393 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization of mice with recombinant BPS protein by the subcutaneous route produced an efficient antigen-specific response, and immunized animals survived challenge with a lethal dose of a virulent strain [PubMed: 11796614]." ; rdfs:label "BPS" ; rdfs:seeAlso "Protegen ID: 850; NCBI Protein GI: 5327234; NCBITaxon: 1311" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012356, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012394 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Intranasal immunization of mice with either SfbI alone or coupled to cholera toxin B subunit (CTB) triggered efficient SfbI-specific humoral (mainly IgG) and lung mucosal (14% of total IgA) responses. SfbI-vaccinated animals showed 80% and 90% protection against homologous and heterologous challenge, respectively [PubMed: 10068585]." ; rdfs:label "SfbI" ; rdfs:seeAlso "Protegen ID: 851; NCBI Nucleotide GI: 511149; NCBI Protein GI: 511150; NCBI Protein Accession: CAA48133.1; NCBITaxon: 1314" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012357, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012395 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice subcutaneously or orally immunized with FBP54 survived significantly longer following the challenge with S. pyogenes than did nonimmunized mice [PubMed: 11159987]." ; rdfs:label "FBP54" ; rdfs:seeAlso "Protegen ID: 852; NCBI Nucleotide GI: 496254; NCBITaxon: 1314" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012357, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012396 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with FbpA were protected from challenge with group A streptococcus [PubMed: 19254483]." ; rdfs:label "FbaA" ; rdfs:seeAlso "Protegen ID: 853; NCBI Protein GI: 14915682; NCBITaxon: 1314" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012357, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012397 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice were intranasally immunized with diphtheria toxoid (DT) conjugated polypeptides encompassing a conformational-constrained B cell epitope of the M1 protein (J8). Vaccinated mice were challenged 10 days after the last boost by the intranasal route. Animals had 60% protection against challenge [PubMed: 16828529]." ; rdfs:label "Emm1" ; rdfs:seeAlso "Protegen ID: 854; NCBI Nucleotide GI: 311757; NCBI Protein GI: 311758; NCBI Protein Accession: CAA44062.1; NCBITaxon: 1314" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012357, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012398 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with Sib 35 enhanced survival rates in mice challenged with a GAS strain, while exhibiting no toxicity in hosts [PubMed: 15990202]." ; rdfs:label "Sib35" ; rdfs:seeAlso "Protegen ID: 855; NCBI Protein GI: 90567992; NCBITaxon: 342023" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012357, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012399 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with the recombinant GlpQ significantly protected rabbits from subsequent T. pallidum challenge, altering lesion development at the sites of challenge [PubMed: 9826352]." ; rdfs:label "GlpQ" ; rdfs:seeAlso "Protegen ID: 856; NCBI Gene GI: 2611763; NCBI Protein GI: 15639249; NCBI Protein Accession: NP_218698; NCBITaxon: 243276" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012358, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012400 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Treponema pallidum-susceptible guinea pigs of strain C4D were immunized with recombinant T. pallidum antigen TmpB. Guinea pigs receiving TmpB antigen demonstrated protection expressed by the development of significantly (P less than 0.01) smaller, atypical lesions of significantly (P less than 0.01) shorter duration and devoid of or containing fewer T. pallidum organisms than lesions in the remaining immunized and control animals [PubMed: 1937794]." ; rdfs:label "TmpB" ; rdfs:seeAlso "Protegen ID: 857; NCBI Gene GI: 2611387; NCBI Protein GI: 15639756; NCBI Protein Accession: NP_219206; NCBITaxon: 243276" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012358, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012401 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with recombinant Tp92 partially protected rabbits from subsequent T. pallidum challenge [PubMed: 10762571]." ; rdfs:label "Tp92" ; rdfs:seeAlso "Protegen ID: 858; NCBI Protein GI: 159158965; NCBITaxon: 243276" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012358, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012402 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Immunization with the recombinant Sip protein efficiently protected CD-1 mice against deadly challenges with six GBS strains of serotypes Ia/c, Ib, II/R, III, V, and VI [PubMed: 10992461]." ; rdfs:label "Sip" ; rdfs:seeAlso "Protegen ID: 859; NCBI Gene GI: 3685788; NCBI Protein GI: 76788047; NCBI Protein Accession: YP_328758; NCBITaxon: 205921" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012356, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012403 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination of mice with the Rib protein protected against two strains of capsular type III and two strains of type II, and vaccination with the alpha protein protected against one strain of type II and one strain of type Ib [PubMed: 8751893]." ; rdfs:label "Rib" ; rdfs:seeAlso "Protegen ID: 860; NCBI Protein GI: 1620648; NCBITaxon: 1311" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0012356, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012404 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mice immunized with p60 encapsulated in liposomes launched a strong CTL response and were protected against a subsequent challenge with L. monocytogenes [PubMed: 18433404]." ; rdfs:label "p60" ; rdfs:seeAlso "Protegen ID: 862; NCBI Protein GI: 215422507; NCBITaxon: 1639" ; rdfs:subClassOf obo:VO_0012369, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012405 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Mouse antiserum directed against the recombinant NucA protein was reactive on Western immunoblots and whole-cell ELISA with all H. influenzae strains tested including Eagan and was bactericidal for two heterologous strains tested. The antiserum also resulted in a log reduction in bacteremia, in an infant-rat protection study with H. influenzae type b as the challenge strain [PubMed: 10768940]." ; rdfs:label "NucA" ; rdfs:seeAlso "Protegen ID: 863; NCBI Protein GI: 4929317; NCBITaxon: 727" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012406 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "When chinchillas were immunized with recombinant P1 (rP1) obtained from one of these isolates (BCH-3), all animals developed antibodies specific for rP1. Immunized animals were protected against disease when challenged with BCH-3, but not with an ompP1 mutant of BCH-3 or a strain (BCH-2) possessing a heterologous P1 (91% identity). We conclude that (i) while P1 induces protection against NTHI-mediated otitis media, development of a polyvalent vaccine reflecting the variability of P1 would be necessary to construct an efficacious vaccine [PubMed: 10899849]." ; rdfs:label "OmpP1" ; rdfs:seeAlso "Protegen ID: 864; NCBI Protein GI: 9716645; NCBITaxon: 727" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010772, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012407 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "Vaccination with the recombinant PstS-1 antigen and cholera toxin significantly protected against the challenge given 10 days later, but only marginally after 12 weeks [PubMed: 10869767]." ; rdfs:label "PstS1" ; rdfs:seeAlso "Protegen ID: 865; NCBI Gene GI: 885724; NCBI Protein GI: 57116801; NCBI Protein Accession: YP_177770; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012408 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "In an ex vivo transfection approach with a retroviral vector a single antigen (hsp70) could evoke strong protection in mice [PubMed: 9234527]." ; rdfs:label "DnaK from Mycobacterium tuberculosis" ; rdfs:seeAlso "Protegen ID: 866; NCBI Gene GI: 885946; NCBI Protein GI: 15607491; NCBI Protein Accession: NP_214864; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0012409 obo:IAO_0000117 "YH, ZX" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:comment "A single DNA vaccine encoding the MPT-83 tuberculosis antigens evoked partial protection against an aerogenic challenge with M. tuberculosis Erdman in the mouse model of pulmonary tuberculosis [PubMed: 10715531]." ; rdfs:label "MPT83" ; rdfs:seeAlso "Protegen ID: 867; NCBI Gene GI: 887155; NCBI Protein GI: 15610010; NCBI Protein Accession: NP_217389; NCBITaxon: 83332" ; rdfs:subClassOf obo:VO_0001232, obo:VO_0010770, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:VO_0000457 ] . obo:VO_0015001 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/803365" ; obo:VO_0003198 "803365" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML [Twinrix]" ; rdfs:subClassOf obo:VO_0003451 . obo:VO_0015003 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/803371" ; obo:VO_0003198 "803371" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Prefilled Syringe [Twinrix]" ; rdfs:subClassOf obo:VO_0015006 . obo:VO_0015004 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/803367" ; obo:VO_0003198 "803367" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "1 ML Hepatitis A Vaccine (Inactivated) Strain HM175 720 UNT/ML / Hepatitis B Surface Antigen Vaccine 0.02 MG/ML Injection [Twinrix]" ; rdfs:subClassOf obo:VO_0015005 . obo:VO_0015005 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657671" ; obo:VO_0003198 "1657671" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Injection [Twinrix]" ; rdfs:subClassOf obo:VO_0003451 . obo:VO_0015006 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/803370" ; obo:VO_0003198 "803370" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis A Vaccine (Inactivated) Strain HM175 / Hepatitis B Surface Antigen Vaccine Prefilled Syringe [Twinrix]" ; rdfs:subClassOf obo:VO_0003451 . obo:VO_0015008 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300468" ; obo:VO_0003198 "1300468" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML Injection [ActHIB]" ; rdfs:subClassOf obo:VO_0015010 . obo:VO_0015009 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300467" ; obo:VO_0003198 "1300467" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML [ActHIB]" ; rdfs:subClassOf obo:VO_0015011 . obo:VO_0015010 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658093" ; obo:VO_0003198 "1658093" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injection [ActHIB]" ; rdfs:subClassOf obo:VO_0015011 . obo:VO_0015011 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1169156" ; obo:VO_0003198 "1169156" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "ActHIB Injectable Product" ; rdfs:subClassOf obo:VO_0000004 . obo:VO_0015012 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300465" ; obo:VO_0003198 "1300465" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML" ; rdfs:subClassOf obo:VO_0015013 . obo:VO_0015013 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300464" ; obo:VO_0003198 "1300464" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine" ; rdfs:subClassOf obo:VO_0015014, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000031 ] . obo:VO_0015014 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/798279" ; obo:VO_0003198 "798279" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine" ; rdfs:subClassOf obo:VO_0000179, obo:VO_0000627, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:VO_0000084 ] . obo:VO_0015015 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1300466" ; obo:VO_0003198 "1300466" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Haemophilus influenzae type b strain 1482, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine 0.068 MG/ML Injection" ; rdfs:subClassOf obo:VO_0015016 . obo:VO_0015016 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658069" ; obo:VO_0003198 "1658069" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injection" ; rdfs:subClassOf obo:VO_0015017 . obo:VO_0015017 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1160291" ; obo:VO_0003198 "1160291" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Haemophilus influenzae type b, capsular polysaccharide inactivated tetanus toxoid conjugate vaccine Injectable Product" ; rdfs:subClassOf obo:VO_0015014 . obo:VO_0015019 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1166419" ; obo:VO_0003198 "1166419" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Engerix-B Injectable Product" ; rdfs:subClassOf obo:VO_0010711 . obo:VO_0015020 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658143" ; obo:VO_0003198 "1658143" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Hepatitis B Surface Antigen Vaccine Injection [Engerix-B]" ; rdfs:subClassOf obo:VO_0015019 . obo:VO_0015022 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1190916" ; obo:VO_0003198 "1190916" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Injection [Tenivac]" ; rdfs:subClassOf obo:VO_0015025 . obo:VO_0015023 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1190919" ; obo:VO_0003198 "1190919" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML Prefilled Syringe [Tenivac]" ; rdfs:subClassOf obo:VO_0015024 . obo:VO_0015024 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1190918" ; obo:VO_0003198 "1190918" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Prefilled Syringe [Tenivac]" ; rdfs:subClassOf obo:VO_0000102 . obo:VO_0015025 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657592" ; obo:VO_0003198 "1657592" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated / tetanus toxoid vaccine, inactivated Injection [Tenivac]" ; rdfs:subClassOf obo:VO_0000102 . obo:VO_0015026 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1190914" ; obo:VO_0003198 "1190914" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Tenivac Injectable Product" ; rdfs:subClassOf obo:VO_0000102 . obo:VO_0015027 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1190912" ; obo:VO_0003198 "1190912" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "diphtheria toxoid vaccine, inactivated 4 UNT/ML / tetanus toxoid vaccine, inactivated 10 UNT/ML [Tenivac]" ; rdfs:subClassOf obo:VO_0000102 . obo:VO_0015028 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292427" ; obo:VO_0003198 "1292427" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML [Varivax]" ; rdfs:subClassOf obo:VO_0000119 . obo:VO_0015029 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1292459" ; obo:VO_0003198 "1292459" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "0.5 ML Varicella-Zoster Virus Vaccine Live (Oka-Merck) strain 2700 UNT/ML Injection [Varivax]" ; rdfs:subClassOf obo:VO_0015031 . obo:VO_0015030 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; 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obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/797635" ; obo:VO_0003198 "797635" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup Y capsular polysaccharide diphtheria toxoid protein conjugate vaccine" ; rdfs:subClassOf obo:VO_0000053 . obo:VO_0015071 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/797634" ; obo:VO_0003198 "797634" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Neisseria meningitidis serogroup W-135 capsular polysaccharide diphtheria toxoid protein conjugate vaccine 0.104 MG/ML" ; rdfs:subClassOf obo:VO_0015069 . obo:VO_0015080 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658702" ; obo:VO_0003198 "1658702" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluzone 2015-2016" ; rdfs:subClassOf obo:VO_0000047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0000200 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003470 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:VO_0003488 ] . obo:VO_0015081 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1658705" ; obo:VO_0003198 "1658705" ; oboInOwl:inSubset "vaccine" ; a owl:Class ; rdfs:label "Fluzone 2015-2016 Injectable Product" ; rdfs:subClassOf obo:VO_0015080 . obo:VO_0015084 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657128" ; obo:VO_0003198 "1657128" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "Influenza A virus (H1N1) antigen" ; rdfs:subClassOf obo:VO_0000919 . obo:VO_0015085 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657131" ; obo:VO_0003198 "1657131" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza A virus (H3N2) antigen" ; rdfs:subClassOf obo:VO_0000919 . obo:VO_0015086 obo:IAO_0000117 "Khadeejah Khan, Oliver He" ; obo:IAO_0000119 "http://purl.bioontology.org/ontology/RXNORM/1657134" ; obo:VO_0003198 "1657134" ; oboInOwl:inSubset "vaccine component" ; a owl:Class ; rdfs:label "influenza B virus antigen" ; rdfs:subClassOf obo:VO_0000919 . obo:VO_0015471 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium falciparum protein" ; rdfs:subClassOf obo:VO_0010771 . obo:VO_0015472 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium knowlesi protein" ; rdfs:subClassOf obo:VO_0010771 . obo:VO_0015473 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium vivax protein" ; rdfs:subClassOf obo:VO_0010771 . obo:VO_0015474 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium yoelii protein" ; rdfs:subClassOf obo:VO_0010771 . obo:VO_0015475 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium berghei protein" ; rdfs:subClassOf obo:VO_0010771 . obo:VO_0015476 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Plasmodium chabaudi protein" ; rdfs:subClassOf obo:VO_0010771 . obo:VO_0015478 oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Leishmania protein" ; rdfs:subClassOf obo:VO_0010755 . obo:VO_0015483 obo:IAO_0000117 "AH" ; oboInOwl:inSubset "protein" ; a owl:Class ; rdfs:label "Giardia lamblia protein" ; rdfs:subClassOf obo:VO_0010829 . obo:VO_0015978 obo:IAO_0000115 "a role that inheres in a cell line repository organization." ; obo:IAO_0000117 "SS, YH" ; oboInOwl:inSubset "role" ; a owl:Class ; rdfs:label "cell line repository role" ; rdfs:subClassOf obo:BFO_0000023 . chebi:charge a owl:AnnotationProperty . chebi:formula a owl:AnnotationProperty . chebi:inchi a owl:AnnotationProperty . chebi:inchikey a owl:AnnotationProperty . chebi:mass a owl:AnnotationProperty . chebi:monoisotopicmass a owl:AnnotationProperty . chebi:smiles a owl:AnnotationProperty . ncbitaxon:has_rank a owl:AnnotationProperty ; rdfs:label "has_rank" . protege:defaultLanguage "en" ; dc:contributor "Chris mungall", "Erica Marcos", "Ningxian Fan", "Paul Fabry", "Randi Vita", "Ryan R. Brinkman", "Shunzhou Deng" ; dc:creator "Alan Ruttenburg", "Alexander D. Diehl", "Amogh Madireddi", "Anna Maria Masci", "Anthony Huffman", "Barry Smith", "Bjoern Peters", "Edison Ong", "Hong Yu", "Jason Hu", "Jie Zheng", "Kallan Roan", "Khadeejah Khan", "Lindsay Cowell", "Melanie Courtot", "Ningxian Fan", "Omar Tibi", "Philip Huang", "Randi Vita", "Rebecca Racz", "Richard H. Scheuermann", "Rohit Goru", "Ronak Sutariya", "Samantha G. Sayers (SGS)", "Thomas Todd", "Yongqun \"Oliver\" He (YH)", "Yu Lin (YL)", "Yuanyi (Penny) Pan", "Zuoshuang \"Allen\" Xiang" ; dc:description "The Vaccine Ontology (VO) is a community-based biomedical ontology in the domain of vaccine and vaccination. VO aims to standardize vaccine types and annotations, integrate various vaccine data, and support computer-assisted reasoning. The VO supports basic vaccine R&D and clincal vaccine usage. VO is being developed as a community-based ontology with support and collaborations from the vaccine and bio-ontology communities."@en ; dc:format "OWL-DL"@en ; dc:subject "An ontology in the domain of vaccine and vaccination"@en ; dc:title "Vaccine Ontology"@en ; terms:license ; a owl:Ontology ; owl:versionIRI ; owl:versionInfo "2024-01-03" . dc:contributor a owl:AnnotationProperty . dc:coverage a owl:AnnotationProperty . dc:creator a owl:AnnotationProperty . dc:date a owl:AnnotationProperty . dc:description a owl:AnnotationProperty . dc:format a owl:AnnotationProperty . dc:identifier a owl:AnnotationProperty . dc:language a owl:AnnotationProperty . dc:license a owl:AnnotationProperty . dc:member a owl:AnnotationProperty . dc:publisher a owl:AnnotationProperty . dc:relation a owl:AnnotationProperty . dc:rights a owl:AnnotationProperty . dc:source a owl:AnnotationProperty . dc:subject a owl:AnnotationProperty . dc:title a owl:AnnotationProperty . dc:type a owl:AnnotationProperty . terms:contributor a owl:AnnotationProperty . terms:created a owl:AnnotationProperty . terms:description a owl:AnnotationProperty . terms:license a owl:AnnotationProperty . terms:source a owl:AnnotationProperty . oboInOwl:SynonymTypeProperty a owl:AnnotationProperty . oboInOwl:created_by a owl:AnnotationProperty . oboInOwl:creation_date a owl:AnnotationProperty . oboInOwl:hasAlternativeId a owl:AnnotationProperty . oboInOwl:hasBroadSynonym obo:IAO_0000115 "An alternative label for a class or property which has a more general meaning than the preferred name/primary label." ; obo:IAO_0000117 ; obo:IAO_0000233 "https://github.com/information-artifact-ontology/ontology-metadata/issues/18" ; a owl:AnnotationProperty ; rdfs:label "has broad synonym"@en ; rdfs:seeAlso "https://github.com/information-artifact-ontology/ontology-metadata/issues/18" ; rdfs:subPropertyOf obo:IAO_0000118 . oboInOwl:hasDbXref a owl:AnnotationProperty ; rdfs:label "database_cross_reference" . oboInOwl:hasExactSynonym obo:IAO_0000115 "An alternative label for a class or property which has the exact same meaning than the preferred name/primary label." ; obo:IAO_0000117 ; obo:IAO_0000233 "https://github.com/information-artifact-ontology/ontology-metadata/issues/20" ; a owl:AnnotationProperty ; rdfs:label "has exact synonym"@en ; rdfs:seeAlso "https://github.com/information-artifact-ontology/ontology-metadata/issues/20" ; rdfs:subPropertyOf obo:IAO_0000118 . oboInOwl:hasNarrowSynonym obo:IAO_0000115 "An alternative label for a class or property which has a more specific meaning than the preferred name/primary label." ; obo:IAO_0000117 ; obo:IAO_0000233 "https://github.com/information-artifact-ontology/ontology-metadata/issues/19" ; a owl:AnnotationProperty ; rdfs:label "has narrow synonym"@en ; rdfs:seeAlso "https://github.com/information-artifact-ontology/ontology-metadata/issues/19" ; rdfs:subPropertyOf obo:IAO_0000118 . oboInOwl:hasOBONamespace a owl:AnnotationProperty . oboInOwl:hasRelatedSynonym obo:IAO_0000115 "An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct." ; obo:IAO_0000117 ; obo:IAO_0000233 "https://github.com/information-artifact-ontology/ontology-metadata/issues/21" ; a owl:AnnotationProperty ; rdfs:label "has related synonym"@en ; rdfs:seeAlso "https://github.com/information-artifact-ontology/ontology-metadata/issues/21" ; rdfs:subPropertyOf obo:IAO_0000118 . oboInOwl:hasSynonym a owl:AnnotationProperty . oboInOwl:hasURI a owl:AnnotationProperty . oboInOwl:id a owl:AnnotationProperty . oboInOwl:inSubset a owl:AnnotationProperty . rdf:PlainLiteral a rdfs:Datatype . rdfs:Literal a rdfs:Datatype . rdfs:comment a owl:AnnotationProperty . rdfs:isDefinedBy a owl:AnnotationProperty . rdfs:label a owl:AnnotationProperty . rdfs:seeAlso a owl:AnnotationProperty . xsd:date a rdfs:Datatype . xsd:dateTime a rdfs:Datatype . xsd:float a rdfs:Datatype . xsd:integer a rdfs:Datatype . xsd:nonNegativeInteger a rdfs:Datatype . xsd:string a rdfs:Datatype . skos:exactMatch a owl:AnnotationProperty . foaf:depicted_by a owl:AnnotationProperty . foaf:depiction a owl:AnnotationProperty . foaf:homepage a owl:AnnotationProperty . foaf:mbox a owl:AnnotationProperty . a swrl:Variable . a swrl:Variable . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000026 ; owl:annotatedTarget "A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000026 ; owl:annotatedTarget "(forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000027 ; owl:annotatedTarget "An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000027 ; owl:annotatedTarget "An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000119 ; owl:annotatedSource obo:BFO_0000027 ; owl:annotatedTarget "ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158." . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000027 ; owl:annotatedTarget "b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000027 ; owl:annotatedTarget "(forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000028 ; owl:annotatedTarget "A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000028 ; owl:annotatedTarget "(forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000029 ; owl:annotatedTarget "b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000029 ; owl:annotatedTarget "(forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000030 ; owl:annotatedTarget "b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:BFO_0000031 ; owl:annotatedTarget "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000031 ; owl:annotatedTarget "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000034 ; owl:annotatedTarget "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000034 ; owl:annotatedTarget "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:BFO_0000035 ; owl:annotatedTarget "p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000035 ; owl:annotatedTarget "Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000035 ; owl:annotatedTarget "(forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000035 ; owl:annotatedTarget "(iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000038 ; owl:annotatedTarget "A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000038 ; owl:annotatedTarget "(forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000040 ; owl:annotatedTarget "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000040 ; owl:annotatedTarget "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000040 ; owl:annotatedTarget "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])"@en . [] a owl:AllDisjointClasses ; owl:members (obo:VO_0005440 obo:VO_0005441 obo:VO_0005442 obo:VO_0005443 obo:VO_0005444 obo:VO_0005445 obo:VO_0005446 ) . [] a owl:AllDisjointClasses ; owl:members (obo:VO_0005440 obo:VO_0005441 obo:VO_0005442 obo:VO_0005443 obo:VO_0005444 obo:VO_0005445 obo:VO_0005446 obo:VO_0005447 ) . [] a owl:AllDisjointClasses ; owl:members (obo:VO_0005440 obo:VO_0005441 obo:VO_0005442 obo:VO_0005443 obo:VO_0005444 obo:VO_0005445 obo:VO_0005446 obo:VO_0005447 obo:VO_0005448 obo:VO_0005449 obo:VO_0005450 obo:VO_0005451 obo:VO_0005452 obo:VO_0005453 obo:VO_0005454 obo:VO_0005455 ) . [] a owl:AllDifferent ; owl:distinctMembers (obo:IAO_0000120 obo:IAO_0000121 obo:IAO_0000122 obo:IAO_0000123 obo:IAO_0000124 obo:IAO_0000125 obo:IAO_0000423 obo:IAO_0000428 ) . [] a owl:AllDifferent ; owl:distinctMembers (obo:IAO_0000226 obo:IAO_0000227 obo:IAO_0000228 obo:IAO_0000229 ) . [] a swrl:Imp ; swrl:body ([ a swrl:IndividualPropertyAtom ; swrl:argument1 ; swrl:argument2 ; swrl:propertyPredicate obo:RO_0000053 ] [ a swrl:ClassAtom ; swrl:argument1 ; swrl:classPredicate obo:BFO_0000016 ] ) ; swrl:head ([ a swrl:IndividualPropertyAtom ; swrl:argument1 ; swrl:argument2 ; swrl:propertyPredicate obo:RO_0000091 ] ) . [] a swrl:Imp ; swrl:body ([ a swrl:IndividualPropertyAtom ; swrl:argument1 ; swrl:argument2 ; swrl:propertyPredicate obo:RO_0000053 ] [ a swrl:ClassAtom ; swrl:argument1 ; swrl:classPredicate obo:BFO_0000019 ] ) ; swrl:head ([ a swrl:IndividualPropertyAtom ; swrl:argument1 ; swrl:argument2 ; swrl:propertyPredicate obo:RO_0000086 ] ) . [] a swrl:Imp ; swrl:body ([ a swrl:IndividualPropertyAtom ; swrl:argument1 ; swrl:argument2 ; swrl:propertyPredicate obo:RO_0000053 ] [ a swrl:ClassAtom ; swrl:argument1 ; swrl:classPredicate obo:BFO_0000023 ] ) ; swrl:head ([ a swrl:IndividualPropertyAtom ; swrl:argument1 ; swrl:argument2 ; swrl:propertyPredicate obo:RO_0000087 ] ) . [] a swrl:Imp ; swrl:body ([ a swrl:IndividualPropertyAtom ; swrl:argument1 ; swrl:argument2 ; swrl:propertyPredicate obo:RO_0000053 ] [ a swrl:ClassAtom ; swrl:argument1 ; swrl:classPredicate obo:BFO_0000034 ] ) ; swrl:head ([ a swrl:IndividualPropertyAtom ; swrl:argument1 ; swrl:argument2 ; swrl:propertyPredicate obo:RO_0000085 ] ) . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000040 ; owl:annotatedTarget "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000040 ; owl:annotatedTarget "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000040 ; owl:annotatedTarget "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:BFO_0000140 ; owl:annotatedTarget "b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000140 ; owl:annotatedTarget "Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions."@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000140 ; owl:annotatedTarget "(iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000142 ; owl:annotatedTarget "a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000142 ; owl:annotatedTarget "(iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:BFO_0000144 ; owl:annotatedTarget "b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000144 ; owl:annotatedTarget "b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000144 ; owl:annotatedTarget "(forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000144 ; owl:annotatedTarget "(iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:BFO_0000145 ; owl:annotatedTarget "b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000145 ; owl:annotatedTarget "(iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000146 ; owl:annotatedTarget "a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000146 ; owl:annotatedTarget "(iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; rdfs:comment "requested by Melanie Courtot" ; rdfs:seeAlso ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000147 ; owl:annotatedTarget "zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona."@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000147 ; owl:annotatedTarget "a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000147 ; owl:annotatedTarget "(iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000148 ; owl:annotatedTarget "A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000148 ; owl:annotatedTarget "(forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000182 ; owl:annotatedTarget "A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])"@en . [] obo:IAO_0000116 "This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation." ; a owl:Axiom ; owl:annotatedProperty rdfs:domain ; owl:annotatedSource obo:RO_0001025 ; owl:annotatedTarget obo:BFO_0000004 . [] obo:IAO_0000116 "This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation." ; a owl:Axiom ; owl:annotatedProperty rdfs:range ; owl:annotatedSource obo:RO_0001025 ; owl:annotatedTarget obo:BFO_0000004 . [] obo:IAO_0010000 ; a owl:Axiom ; rdfs:comment "per discussion with Barry Smith" ; rdfs:seeAlso ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000001 ; owl:annotatedTarget "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000001 ; owl:annotatedTarget "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000002 ; owl:annotatedTarget "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; rdfs:comment "per discussion with Barry Smith" ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000003 ; owl:annotatedTarget "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process."@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000003 ; owl:annotatedTarget "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000003 ; owl:annotatedTarget "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000003 ; owl:annotatedTarget "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000003 ; owl:annotatedTarget "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000003 ; owl:annotatedTarget "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000003 ; owl:annotatedTarget "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:BFO_0000004 ; owl:annotatedTarget "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000004 ; owl:annotatedTarget "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000004 ; owl:annotatedTarget "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000004 ; owl:annotatedTarget "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000004 ; owl:annotatedTarget "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000004 ; owl:annotatedTarget "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; rdfs:comment "per discussion with Barry Smith" ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000006 ; owl:annotatedTarget "Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional."@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000006 ; owl:annotatedTarget "A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000006 ; owl:annotatedTarget "All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000006 ; owl:annotatedTarget "(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000006 ; owl:annotatedTarget "(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; rdfs:comment "per discussion with Barry Smith" ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000008 ; owl:annotatedTarget "Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000008 ; owl:annotatedTarget "A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000008 ; owl:annotatedTarget "All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000008 ; owl:annotatedTarget "Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000008 ; owl:annotatedTarget "(forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000008 ; owl:annotatedTarget "(forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000008 ; owl:annotatedTarget "(forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000009 ; owl:annotatedTarget "A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000009 ; owl:annotatedTarget "(forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "(forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "(forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "(forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "(forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000011 ; owl:annotatedTarget "(forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:BFO_0000015 ; owl:annotatedTarget "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000015 ; owl:annotatedTarget "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000016 ; owl:annotatedTarget "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000016 ; owl:annotatedTarget "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000016 ; owl:annotatedTarget "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000016 ; owl:annotatedTarget "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000017 ; owl:annotatedTarget "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000017 ; owl:annotatedTarget "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000017 ; owl:annotatedTarget "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000017 ; owl:annotatedTarget "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000018 ; owl:annotatedTarget "A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000018 ; owl:annotatedTarget "(forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000019 ; owl:annotatedTarget "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000601 ; owl:annotatedSource obo:BFO_0000019 ; owl:annotatedTarget "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000019 ; owl:annotatedTarget "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000019 ; owl:annotatedTarget "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:BFO_0000020 ; owl:annotatedTarget "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; rdfs:comment "per discussion with Barry Smith" ; owl:annotatedProperty obo:IAO_0000116 ; owl:annotatedSource obo:BFO_0000020 ; owl:annotatedTarget "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc."@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000020 ; owl:annotatedTarget "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000023 ; owl:annotatedTarget "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000023 ; owl:annotatedTarget "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000600 ; owl:annotatedSource obo:BFO_0000024 ; owl:annotatedTarget "b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])"@en . [] obo:IAO_0010000 ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000602 ; owl:annotatedSource obo:BFO_0000024 ; owl:annotatedTarget "(forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004] " .