@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix : <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-base.owl#> .
@prefix cl: <http://purl.obolibrary.org/obo/cl#> .
@prefix dc: <http://purl.org/dc/elements/1.1/> .
@prefix go: <http://purl.obolibrary.org/obo/go#> .
@prefix pr: <http://purl.obolibrary.org/obo/pr#> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xml: <http://www.w3.org/XML/1998/namespace> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix caro: <http://purl.obolibrary.org/obo/caro#> .
@prefix cito: <http://purl.org/spar/cito/> .
@prefix core: <http://purl.obolibrary.org/obo/uberon/core#> .
@prefix fbbt: <http://purl.obolibrary.org/obo/fbbt#> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix obda: <https://w3id.org/obda/vocabulary#> .
@prefix obo1: <http://www.geneontology.org/formats/oboInOwl#http://purl.obolibrary.org/obo/> .
@prefix pato: <http://purl.obolibrary.org/obo/pato#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix chebi: <http://purl.obolibrary.org/obo/chebi/> .
@prefix core1: <http://purl.obolibrary.org/obo/core#> .
@prefix swrla: <http://swrl.stanford.edu/ontologies/3.3/swrla.owl#> .
@prefix terms: <http://purl.org/dc/terms/> .
@prefix chebi2: <http://purl.obolibrary.org/obo/chebi#2> .
@prefix chebi3: <http://purl.obolibrary.org/obo/chebi#3> .
@prefix chebi4: <http://purl.obolibrary.org/obo/chebi#1> .
@prefix chebi5: <http://purl.obolibrary.org/obo/chebi#> .
@prefix terms2: <http://www.geneontology.org/formats/oboInOwl#http://purl.org/dc/terms/> .
@prefix ubprop: <http://purl.obolibrary.org/obo/ubprop#> .
@prefix subsets: <http://purl.obolibrary.org/obo/ro/subsets#> .
@prefix taxslim: <http://purl.obolibrary.org/obo/ncbitaxon/subsets/taxslim#> .
@prefix oboInOwl: <http://www.geneontology.org/formats/oboInOwl#> .
@prefix ncbitaxon: <http://purl.obolibrary.org/obo/ncbitaxon#> .
@prefix oboInOwl1: <ttp://www.geneontology.org/formats/oboInOwl#> .
@prefix wbphenotype: <http://purl.obolibrary.org/obo/wbphenotype#> .
@prefix caloha-reqs-vetted: <http://purl.obolibrary.org/obo/caloha-reqs-vetted#> .

obo:BFO_0000050
    a owl:ObjectProperty .

obo:BFO_0000051
    a owl:ObjectProperty .

obo:BFO_0000066
    a owl:ObjectProperty .

obo:BFO_0000070
    a owl:ObjectProperty .

obo:CARO_0010004
    a owl:Class .

obo:CHEBI_15347
    a owl:Class .

obo:CHEBI_15355
    a owl:Class .

obo:CHEBI_15422
    a owl:Class .

obo:CHEBI_15837
    a owl:Class .

obo:CHEBI_15854
    a owl:Class .

obo:CHEBI_15858
    a owl:Class .

obo:CHEBI_16133
    a owl:Class .

obo:CHEBI_16136
    a owl:Class .

obo:CHEBI_16236
    a owl:Class .

obo:CHEBI_16240
    a owl:Class .

obo:CHEBI_16382
    a owl:Class .

obo:CHEBI_16526
    a owl:Class .

obo:CHEBI_16583
    a owl:Class .

obo:CHEBI_16856
    a owl:Class .

obo:CHEBI_16865
    a owl:Class .

obo:CHEBI_17051
    a owl:Class .

obo:CHEBI_17134
    a owl:Class .

obo:CHEBI_17489
    a owl:Class .

obo:CHEBI_17688
    a owl:Class .

obo:CHEBI_17996
    a owl:Class .

obo:CHEBI_18059
    a owl:Class .

obo:CHEBI_18099
    a owl:Class .

obo:CHEBI_18243
    a owl:Class .

obo:CHEBI_18248
    a owl:Class .

obo:CHEBI_18291
    a owl:Class .

obo:CHEBI_18723
    a owl:Class .

obo:CHEBI_22633
    a owl:Class .

obo:CHEBI_22698
    a owl:Class .

obo:CHEBI_22951
    a owl:Class .

obo:CHEBI_22977
    a owl:Class .

obo:CHEBI_23359
    a owl:Class .

obo:CHEBI_23447
    a owl:Class .

obo:CHEBI_23888
    a owl:Class .

obo:CHEBI_23994
    a owl:Class .

obo:CHEBI_24431
    a owl:Class .

obo:CHEBI_25016
    a owl:Class .

obo:CHEBI_25094
    a owl:Class .

obo:CHEBI_25107
    a owl:Class .

obo:CHEBI_25195
    a owl:Class .

obo:CHEBI_25212
    a owl:Class .

obo:CHEBI_25255
    a owl:Class .

obo:CHEBI_25435
    a owl:Class .

obo:CHEBI_2555
    a owl:Class .

obo:CHEBI_25579
    a owl:Class .

obo:CHEBI_25805
    a owl:Class .

obo:CHEBI_25944
    a owl:Class .

obo:CHEBI_26034
    a owl:Class .

obo:CHEBI_26216
    a owl:Class .

obo:CHEBI_26523
    a owl:Class .

obo:CHEBI_26708
    a owl:Class .

obo:CHEBI_26710
    a owl:Class .

obo:CHEBI_27363
    a owl:Class .

obo:CHEBI_27563
    a owl:Class .

obo:CHEBI_27638
    a owl:Class .

obo:CHEBI_27682
    a owl:Class .

obo:CHEBI_27732
    a owl:Class .

obo:CHEBI_27780
    a owl:Class .

obo:CHEBI_27882
    a owl:Class .

obo:CHEBI_28087
    a owl:Class .

obo:CHEBI_28112
    a owl:Class .

obo:CHEBI_2814
    a owl:Class .

obo:CHEBI_28260
    a owl:Class .

obo:CHEBI_28694
    a owl:Class .

obo:CHEBI_28790
    a owl:Class .

obo:CHEBI_29108
    a owl:Class .

obo:CHEBI_29222
    a owl:Class .

obo:CHEBI_29699
    a owl:Class .

obo:CHEBI_30052
    a owl:Class .

obo:CHEBI_30145
    a owl:Class .

obo:CHEBI_30185
    a owl:Class .

obo:CHEBI_30297
    a owl:Class .

obo:CHEBI_30413
    a owl:Class .

obo:CHEBI_30512
    a owl:Class .

obo:CHEBI_30513
    a owl:Class .

obo:CHEBI_30953
    a owl:Class .

obo:CHEBI_31206
    a owl:Class .

obo:CHEBI_32954
    a owl:Class .

obo:CHEBI_33083
    a owl:Class .

obo:CHEBI_33216
    a owl:Class .

obo:CHEBI_33252
    a owl:Class .

obo:CHEBI_33290
    a owl:Class .

obo:CHEBI_33521
    a owl:Class .

obo:CHEBI_33699
    a owl:Class .

obo:CHEBI_34905
    a owl:Class .

obo:CHEBI_35366
    a owl:Class .

obo:CHEBI_35623
    a owl:Class .

obo:CHEBI_35702
    a owl:Class .

obo:CHEBI_3638
    a owl:Class .

obo:CHEBI_37415
    a owl:Class .

obo:CHEBI_37532
    a owl:Class .

obo:CHEBI_37868
    a owl:Class .

obo:CHEBI_37887
    a owl:Class .

obo:CHEBI_38324
    a owl:Class .

obo:CHEBI_38366
    a owl:Class .

obo:CHEBI_38462
    a owl:Class .

obo:CHEBI_38808
    a owl:Class .

obo:CHEBI_38867
    a owl:Class .

obo:CHEBI_39214
    a owl:Class .

obo:CHEBI_4046
    a owl:Class .

obo:CHEBI_4290
    a owl:Class .

obo:CHEBI_44423
    a owl:Class .

obo:CHEBI_46345
    a owl:Class .

obo:CHEBI_472805
    a owl:Class .

obo:CHEBI_47499
    a owl:Class .

obo:CHEBI_4781
    a owl:Class .

obo:CHEBI_4792
    a owl:Class .

obo:CHEBI_4887
    a owl:Class .

obo:CHEBI_50826
    a owl:Class .

obo:CHEBI_50949
    a owl:Class .

obo:CHEBI_51137
    a owl:Class .

obo:CHEBI_5118
    a owl:Class .

obo:CHEBI_5615
    a owl:Class .

obo:CHEBI_6015
    a owl:Class .

obo:CHEBI_6078
    a owl:Class .

obo:CHEBI_63510
    a owl:Class .

obo:CHEBI_64203
    a owl:Class .

obo:CHEBI_6432
    a owl:Class .

obo:CHEBI_6835
    a owl:Class .

obo:CHEBI_7035
    a owl:Class .

obo:CHEBI_8081
    a owl:Class .

obo:CHEBI_9727
    a owl:Class .

obo:CL_0000000
    a owl:Class .

obo:CL_0000007
    a owl:Class .

obo:CL_0000023
    a owl:Class .

obo:CL_0000025
    a owl:Class .

obo:CL_0000066
    a owl:Class .

obo:CL_0000086
    a owl:Class .

obo:CL_0000300
    a owl:Class .

obo:CL_0000365
    a owl:Class .

obo:CL_0000411
    a owl:Class .

obo:CL_0000540
    a owl:Class .

obo:CL_0000586
    a owl:Class .

obo:CL_0000618
    a owl:Class .

obo:CL_0002371
    a owl:Class .

obo:GO_0000070
    a owl:Class .

obo:GO_0000077
    a owl:Class .

obo:GO_0000184
    a owl:Class .

obo:GO_0000226
    a owl:Class .

obo:GO_0000278
    a owl:Class .

obo:GO_0000280
    a owl:Class .

obo:GO_0000374
    a owl:Class .

obo:GO_0000398
    a owl:Class .

obo:GO_0000423
    a owl:Class .

obo:GO_0000723
    a owl:Class .

obo:GO_0000768
    a owl:Class .

obo:GO_0000781
    a owl:Class .

obo:GO_0000819
    a owl:Class .

obo:GO_0000910
    a owl:Class .

obo:GO_0000932
    a owl:Class .

obo:GO_0001666
    a owl:Class .

obo:GO_0001708
    a owl:Class .

obo:GO_0001764
    a owl:Class .

obo:GO_0001939
    a owl:Class .

obo:GO_0001940
    a owl:Class .

obo:GO_0001966
    a owl:Class .

obo:GO_0002064
    a owl:Class .

obo:GO_0002164
    a owl:Class .

obo:GO_0003824
    a owl:Class .

obo:GO_0003990
    a owl:Class .

obo:GO_0005102
    a owl:Class .

obo:GO_0005575
    a owl:Class .

obo:GO_0005604
    a owl:Class .

obo:GO_0005623
    a owl:Class .

obo:GO_0005634
    a owl:Class .

obo:GO_0005643
    a owl:Class .

obo:GO_0005694
    a owl:Class .

obo:GO_0005712
    a owl:Class .

obo:GO_0005730
    a owl:Class .

obo:GO_0005737
    a owl:Class .

obo:GO_0005739
    a owl:Class .

obo:GO_0005764
    a owl:Class .

obo:GO_0005768
    a owl:Class .

obo:GO_0005769
    a owl:Class .

obo:GO_0005770
    a owl:Class .

obo:GO_0005777
    a owl:Class .

obo:GO_0005783
    a owl:Class .

obo:GO_0005794
    a owl:Class .

obo:GO_0005818
    a owl:Class .

obo:GO_0005819
    a owl:Class .

obo:GO_0005829
    a owl:Class .

obo:GO_0005863
    a owl:Class .

obo:GO_0005884
    a owl:Class .

obo:GO_0005886
    a owl:Class .

obo:GO_0005911
    a owl:Class .

obo:GO_0005912
    a owl:Class .

obo:GO_0005923
    a owl:Class .

obo:GO_0005929
    a owl:Class .

obo:GO_0005930
    a owl:Class .

obo:GO_0006259
    a owl:Class .

obo:GO_0006260
    a owl:Class .

obo:GO_0006310
    a owl:Class .

obo:GO_0006351
    a owl:Class .

obo:GO_0006396
    a owl:Class .

obo:GO_0006401
    a owl:Class .

obo:GO_0006406
    a owl:Class .

obo:GO_0006412
    a owl:Class .

obo:GO_0006468
    a owl:Class .

obo:GO_0006479
    a owl:Class .

obo:GO_0006611
    a owl:Class .

obo:GO_0006629
    a owl:Class .

obo:GO_0006887
    a owl:Class .

obo:GO_0006897
    a owl:Class .

obo:GO_0006898
    a owl:Class .

obo:GO_0006913
    a owl:Class .

obo:GO_0006914
    a owl:Class .

obo:GO_0006915
    a owl:Class .

obo:GO_0006935
    a owl:Class .

obo:GO_0006936
    a owl:Class .

obo:GO_0006950
    a owl:Class .

obo:GO_0006970
    a owl:Class .

obo:GO_0006979
    a owl:Class .

obo:GO_0006983
    a owl:Class .

obo:GO_0006986
    a owl:Class .

obo:GO_0006996
    a owl:Class .

obo:GO_0007010
    a owl:Class .

obo:GO_0007019
    a owl:Class .

obo:GO_0007020
    a owl:Class .

obo:GO_0007040
    a owl:Class .

obo:GO_0007049
    a owl:Class .

obo:GO_0007051
    a owl:Class .

obo:GO_0007059
    a owl:Class .

obo:GO_0007091
    a owl:Class .

obo:GO_0007097
    a owl:Class .

obo:GO_0007129
    a owl:Class .

obo:GO_0007140
    a owl:Class .

obo:GO_0007155
    a owl:Class .

obo:GO_0007163
    a owl:Class .

obo:GO_0007165
    a owl:Class .

obo:GO_0007267
    a owl:Class .

obo:GO_0007268
    a owl:Class .

obo:GO_0007271
    a owl:Class .

obo:GO_0007274
    a owl:Class .

obo:GO_0007276
    a owl:Class .

obo:GO_0007281
    a owl:Class .

obo:GO_0007283
    a owl:Class .

obo:GO_0007285
    a owl:Class .

obo:GO_0007286
    a owl:Class .

obo:GO_0007289
    a owl:Class .

obo:GO_0007296
    a owl:Class .

obo:GO_0007320
    a owl:Class .

obo:GO_0007369
    a owl:Class .

obo:GO_0007399
    a owl:Class .

obo:GO_0007411
    a owl:Class .

obo:GO_0007413
    a owl:Class .

obo:GO_0007416
    a owl:Class .

obo:GO_0007530
    a owl:Class .

obo:GO_0007549
    a owl:Class .

obo:GO_0007568
    a owl:Class .

obo:GO_0007610
    a owl:Class .

obo:GO_0007613
    a owl:Class .

obo:GO_0007617
    a owl:Class .

obo:GO_0007618
    a owl:Class .

obo:GO_0007620
    a owl:Class .

obo:GO_0007622
    a owl:Class .

obo:GO_0007626
    a owl:Class .

obo:GO_0007631
    a owl:Class .

obo:GO_0007635
    a owl:Class .

obo:GO_0008021
    a owl:Class .

obo:GO_0008150
    a owl:Class .

obo:GO_0008152
    a owl:Class .

obo:GO_0008219
    a owl:Class .

obo:GO_0008283
    a owl:Class .

obo:GO_0008291
    a owl:Class .

obo:GO_0008306
    a owl:Class .

obo:GO_0008354
    a owl:Class .

obo:GO_0008356
    a owl:Class .

obo:GO_0008406
    a owl:Class .

obo:GO_0008584
    a owl:Class .

obo:GO_0008610
    a owl:Class .

obo:GO_0008630
    a owl:Class .

obo:GO_0009058
    a owl:Class .

obo:GO_0009266
    a owl:Class .

obo:GO_0009268
    a owl:Class .

obo:GO_0009269
    a owl:Class .

obo:GO_0009299
    a owl:Class .

obo:GO_0009306
    a owl:Class .

obo:GO_0009408
    a owl:Class .

obo:GO_0009411
    a owl:Class .

obo:GO_0009416
    a owl:Class .

obo:GO_0009566
    a owl:Class .

obo:GO_0009605
    a owl:Class .

obo:GO_0009611
    a owl:Class .

obo:GO_0009629
    a owl:Class .

obo:GO_0009636
    a owl:Class .

obo:GO_0009790
    a owl:Class .

obo:GO_0009791
    a owl:Class .

obo:GO_0010037
    a owl:Class .

obo:GO_0010042
    a owl:Class .

obo:GO_0010044
    a owl:Class .

obo:GO_0010165
    a owl:Class .

obo:GO_0010212
    a owl:Class .

obo:GO_0010260
    a owl:Class .

obo:GO_0010269
    a owl:Class .

obo:GO_0010288
    a owl:Class .

obo:GO_0010332
    a owl:Class .

obo:GO_0010467
    a owl:Class .

obo:GO_0012501
    a owl:Class .

obo:GO_0014076
    a owl:Class .

obo:GO_0016043
    a owl:Class .

obo:GO_0016049
    a owl:Class .

obo:GO_0016050
    a owl:Class .

obo:GO_0016070
    a owl:Class .

obo:GO_0016079
    a owl:Class .

obo:GO_0016192
    a owl:Class .

obo:GO_0016203
    a owl:Class .

obo:GO_0016246
    a owl:Class .

obo:GO_0016358
    a owl:Class .

obo:GO_0016477
    a owl:Class .

obo:GO_0016482
    a owl:Class .

obo:GO_0016757
    a owl:Class .

obo:GO_0018985
    a owl:Class .

obo:GO_0018991
    a owl:Class .

obo:GO_0019538
    a owl:Class .

obo:GO_0019722
    a owl:Class .

obo:GO_0022611
    a owl:Class .

obo:GO_0022618
    a owl:Class .

obo:GO_0030036
    a owl:Class .

obo:GO_0030037
    a owl:Class .

obo:GO_0030054
    a owl:Class .

obo:GO_0030104
    a owl:Class .

obo:GO_0030154
    a owl:Class .

obo:GO_0030163
    a owl:Class .

obo:GO_0030261
    a owl:Class .

obo:GO_0030421
    a owl:Class .

obo:GO_0030424
    a owl:Class .

obo:GO_0030425
    a owl:Class .

obo:GO_0030534
    a owl:Class .

obo:GO_0030537
    a owl:Class .

obo:GO_0030588
    a owl:Class .

obo:GO_0030590
    a owl:Class .

obo:GO_0030728
    a owl:Class .

obo:GO_0030968
    a owl:Class .

obo:GO_0031012
    a owl:Class .

obo:GO_0031129
    a owl:Class .

obo:GO_0031143
    a owl:Class .

obo:GO_0031175
    a owl:Class .

obo:GO_0031430
    a owl:Class .

obo:GO_0031468
    a owl:Class .

obo:GO_0031573
    a owl:Class .

obo:GO_0031577
    a owl:Class .

obo:GO_0031965
    a owl:Class .

obo:GO_0031982
    a owl:Class .

obo:GO_0032094
    a owl:Class .

obo:GO_0032154
    a owl:Class .

obo:GO_0032502
    a owl:Class .

obo:GO_0032940
    a owl:Class .

obo:GO_0032956
    a owl:Class .

obo:GO_0032982
    a owl:Class .

obo:GO_0033059
    a owl:Class .

obo:GO_0033313
    a owl:Class .

obo:GO_0033316
    a owl:Class .

obo:GO_0033363
    a owl:Class .

obo:GO_0033554
    a owl:Class .

obo:GO_0034059
    a owl:Class .

obo:GO_0034599
    a owl:Class .

obo:GO_0034606
    a owl:Class .

obo:GO_0034608
    a owl:Class .

obo:GO_0034609
    a owl:Class .

obo:GO_0034613
    a owl:Class .

obo:GO_0034644
    a owl:Class .

obo:GO_0034976
    a owl:Class .

obo:GO_0035046
    a owl:Class .

obo:GO_0035047
    a owl:Class .

obo:GO_0035176
    a owl:Class .

obo:GO_0035177
    a owl:Class .

obo:GO_0035188
    a owl:Class .

obo:GO_0035825
    a owl:Class .

obo:GO_0035882
    a owl:Class .

obo:GO_0035915
    a owl:Class .

obo:GO_0036194
    a owl:Class .

obo:GO_0036211
    a owl:Class .

obo:GO_0040004
    a owl:Class .

obo:GO_0040007
    a owl:Class .

obo:GO_0040011
    a owl:Class .

obo:GO_0040022
    a owl:Class .

obo:GO_0040024
    a owl:Class .

obo:GO_0040025
    a owl:Class .

obo:GO_0040034
    a owl:Class .

obo:GO_0040038
    a owl:Class .

obo:GO_0040040
    a owl:Class .

obo:GO_0042023
    a owl:Class .

obo:GO_0042048
    a owl:Class .

obo:GO_0042073
    a owl:Class .

obo:GO_0042133
    a owl:Class .

obo:GO_0042221
    a owl:Class .

obo:GO_0042331
    a owl:Class .

obo:GO_0042335
    a owl:Class .

obo:GO_0042416
    a owl:Class .

obo:GO_0042417
    a owl:Class .

obo:GO_0042420
    a owl:Class .

obo:GO_0042427
    a owl:Class .

obo:GO_0042428
    a owl:Class .

obo:GO_0042429
    a owl:Class .

obo:GO_0042493
    a owl:Class .

obo:GO_0042594
    a owl:Class .

obo:GO_0042713
    a owl:Class .

obo:GO_0042810
    a owl:Class .

obo:GO_0043005
    a owl:Class .

obo:GO_0043050
    a owl:Class .

obo:GO_0043052
    a owl:Class .

obo:GO_0043053
    a owl:Class .

obo:GO_0043054
    a owl:Class .

obo:GO_0043057
    a owl:Class .

obo:GO_0043068
    a owl:Class .

obo:GO_0043186
    a owl:Class .

obo:GO_0043226
    a owl:Class .

obo:GO_0043227
    a owl:Class .

obo:GO_0043473
    a owl:Class .

obo:GO_0043652
    a owl:Class .

obo:GO_0044237
    a owl:Class .

obo:GO_0044818
    a owl:Class .

obo:GO_0044819
    a owl:Class .

obo:GO_0044840
    a owl:Class .

obo:GO_0045087
    a owl:Class .

obo:GO_0045120
    a owl:Class .

obo:GO_0045132
    a owl:Class .

obo:GO_0045161
    a owl:Class .

obo:GO_0045202
    a owl:Class .

obo:GO_0046333
    a owl:Class .

obo:GO_0046785
    a owl:Class .

obo:GO_0046903
    a owl:Class .

obo:GO_0046959
    a owl:Class .

obo:GO_0048066
    a owl:Class .

obo:GO_0048284
    a owl:Class .

obo:GO_0048468
    a owl:Class .

obo:GO_0048477
    a owl:Class .

obo:GO_0048488
    a owl:Class .

obo:GO_0048490
    a owl:Class .

obo:GO_0048511
    a owl:Class .

obo:GO_0048512
    a owl:Class .

obo:GO_0048540
    a owl:Class .

obo:GO_0048565
    a owl:Class .

obo:GO_0048589
    a owl:Class .

obo:GO_0048599
    a owl:Class .

obo:GO_0048666
    a owl:Class .

obo:GO_0048786
    a owl:Class .

obo:GO_0048846
    a owl:Class .

obo:GO_0048880
    a owl:Class .

obo:GO_0050821
    a owl:Class .

obo:GO_0050848
    a owl:Class .

obo:GO_0050896
    a owl:Class .

obo:GO_0050918
    a owl:Class .

obo:GO_0050919
    a owl:Class .

obo:GO_0051081
    a owl:Class .

obo:GO_0051168
    a owl:Class .

obo:GO_0051170
    a owl:Class .

obo:GO_0051225
    a owl:Class .

obo:GO_0051231
    a owl:Class .

obo:GO_0051259
    a owl:Class .

obo:GO_0051293
    a owl:Class .

obo:GO_0051294
    a owl:Class .

obo:GO_0051301
    a owl:Class .

obo:GO_0051310
    a owl:Class .

obo:GO_0051318
    a owl:Class .

obo:GO_0051321
    a owl:Class .

obo:GO_0051402
    a owl:Class .

obo:GO_0051452
    a owl:Class .

obo:GO_0051647
    a owl:Class .

obo:GO_0051726
    a owl:Class .

obo:GO_0051932
    a owl:Class .

obo:GO_0051964
    a owl:Class .

obo:GO_0055001
    a owl:Class .

obo:GO_0055037
    a owl:Class .

obo:GO_0060107
    a owl:Class .

obo:GO_0060109
    a owl:Class .

obo:GO_0060179
    a owl:Class .

obo:GO_0060280
    a owl:Class .

obo:GO_0060322
    a owl:Class .

obo:GO_0060465
    a owl:Class .

obo:GO_0060756
    a owl:Class .

obo:GO_0061564
    a owl:Class .

obo:GO_0065003
    a owl:Class .

obo:GO_0065004
    a owl:Class .

obo:GO_0070160
    a owl:Class .

obo:GO_0070265
    a owl:Class .

obo:GO_0071028
    a owl:Class .

obo:GO_0071470
    a owl:Class .

obo:GO_0071479
    a owl:Class .

obo:GO_0071480
    a owl:Class .

obo:GO_0072347
    a owl:Class .

obo:GO_0072686
    a owl:Class .

obo:GO_0072687
    a owl:Class .

obo:GO_0072710
    a owl:Class .

obo:GO_0090664
    a owl:Class .

obo:GO_0097091
    a owl:Class .

obo:GO_0098542
    a owl:Class .

obo:GO_0098609
    a owl:Class .

obo:GO_0098793
    a owl:Class .

obo:GO_0099636
    a owl:Class .

obo:GO_1901530
    a owl:Class .

obo:GO_1901561
    a owl:Class .

obo:GO_1901562
    a owl:Class .

obo:GO_1903046
    a owl:Class .

obo:GO_1903047
    a owl:Class .

obo:GO_1903537
    a owl:Class .

obo:GO_1904145
    a owl:Class .

obo:GO_1904356
    a owl:Class .

obo:GO_1904576
    a owl:Class .

obo:GO_1990840
    a owl:Class .

obo:IAO_0000115
    a owl:AnnotationProperty ;
    rdfs:label "definition" .

obo:IAO_0000231
    a owl:AnnotationProperty .

obo:IAO_0000700
    a owl:AnnotationProperty .

obo:IAO_0100001
    a owl:AnnotationProperty .

obo:PATO_0000001
    a owl:Class .

obo:PATO_0000008
    a owl:Class .

obo:PATO_0000025
    a owl:Class .

obo:PATO_0000033
    a owl:Class .

obo:PATO_0000044
    a owl:Class .

obo:PATO_0000050
    a owl:Class .

obo:PATO_0000051
    a owl:Class .

obo:PATO_0000052
    a owl:Class .

obo:PATO_0000060
    a owl:Class .

obo:PATO_0000070
    a owl:Class .

obo:PATO_0000077
    a owl:Class .

obo:PATO_0000080
    a owl:Class .

obo:PATO_0000082
    a owl:Class .

obo:PATO_0000117
    a owl:Class .

obo:PATO_0000133
    a owl:Class .

obo:PATO_0000140
    a owl:Class .

obo:PATO_0000141
    a owl:Class .

obo:PATO_0000161
    a owl:Class .

obo:PATO_0000188
    a owl:Class .

obo:PATO_0000274
    a owl:Class .

obo:PATO_0000276
    a owl:Class .

obo:PATO_0000279
    a owl:Class .

obo:PATO_0000297
    a owl:Class .

obo:PATO_0000300
    a owl:Class .

obo:PATO_0000303
    a owl:Class .

obo:PATO_0000304
    a owl:Class .

obo:PATO_0000327
    a owl:Class .

obo:PATO_0000328
    a owl:Class .

obo:PATO_0000330
    a owl:Class .

obo:PATO_0000375
    a owl:Class .

obo:PATO_0000381
    a owl:Class .

obo:PATO_0000384
    a owl:Class .

obo:PATO_0000402
    a owl:Class .

obo:PATO_0000404
    a owl:Class .

obo:PATO_0000411
    a owl:Class .

obo:PATO_0000460
    a owl:Class .

obo:PATO_0000462
    a owl:Class .

obo:PATO_0000467
    a owl:Class .

obo:PATO_0000470
    a owl:Class .

obo:PATO_0000488
    a owl:Class .

obo:PATO_0000498
    a owl:Class .

obo:PATO_0000502
    a owl:Class .

obo:PATO_0000513
    a owl:Class .

obo:PATO_0000516
    a owl:Class .

obo:PATO_0000569
    a owl:Class .

obo:PATO_0000573
    a owl:Class .

obo:PATO_0000574
    a owl:Class .

obo:PATO_0000584
    a owl:Class .

obo:PATO_0000585
    a owl:Class .

obo:PATO_0000586
    a owl:Class .

obo:PATO_0000587
    a owl:Class .

obo:PATO_0000592
    a owl:Class .

obo:PATO_0000616
    a owl:Class .

obo:PATO_0000617
    a owl:Class .

obo:PATO_0000625
    a owl:Class .

obo:PATO_0000628
    a owl:Class .

obo:PATO_0000639
    a owl:Class .

obo:PATO_0000642
    a owl:Class .

obo:PATO_0000648
    a owl:Class .

obo:PATO_0000688
    a owl:Class .

obo:PATO_0000689
    a owl:Class .

obo:PATO_0000694
    a owl:Class .

obo:PATO_0000718
    a owl:Class .

obo:PATO_0000760
    a owl:Class .

obo:PATO_0000763
    a owl:Class .

obo:PATO_0000770
    a owl:Class .

obo:PATO_0000911
    a owl:Class .

obo:PATO_0000912
    a owl:Class .

obo:PATO_0000937
    a owl:Class .

obo:PATO_0000956
    oboInOwl:hasAlternativeId "WBPhenotype:0000311" ;
    a owl:Class .

obo:PATO_0000964
    a owl:Class .

obo:PATO_0001005
    a owl:Class .

obo:PATO_0001162
    a owl:Class .

obo:PATO_0001163
    a owl:Class .

obo:PATO_0001178
    a owl:Class .

obo:PATO_0001192
    a owl:Class .

obo:PATO_0001227
    a owl:Class .

obo:PATO_0001236
    a owl:Class .

obo:PATO_0001242
    a owl:Class .

obo:PATO_0001340
    a owl:Class .

obo:PATO_0001362
    a owl:Class .

obo:PATO_0001422
    a owl:Class .

obo:PATO_0001444
    a owl:Class .

obo:PATO_0001453
    a owl:Class .

obo:PATO_0001457
    a owl:Class .

obo:PATO_0001472
    a owl:Class .

obo:PATO_0001477
    a owl:Class .

obo:PATO_0001492
    a owl:Class .

obo:PATO_0001495
    a owl:Class .

obo:PATO_0001511
    a owl:Class .

obo:PATO_0001551
    a owl:Class .

obo:PATO_0001552
    a owl:Class .

obo:PATO_0001555
    a owl:Class .

obo:PATO_0001558
    a owl:Class .

obo:PATO_0001570
    a owl:Class .

obo:PATO_0001597
    a owl:Class .

obo:PATO_0001598
    a owl:Class .

obo:PATO_0001599
    a owl:Class .

obo:PATO_0001603
    a owl:Class .

obo:PATO_0001604
    a owl:Class .

obo:PATO_0001624
    a owl:Class .

obo:PATO_0001632
    a owl:Class .

obo:PATO_0001633
    a owl:Class .

obo:PATO_0001650
    a owl:Class .

obo:PATO_0001651
    a owl:Class .

obo:PATO_0001652
    a owl:Class .

obo:PATO_0001677
    a owl:Class .

obo:PATO_0001754
    a owl:Class .

obo:PATO_0001767
    a owl:Class .

obo:PATO_0001769
    a owl:Class .

obo:PATO_0001780
    a owl:Class .

obo:PATO_0001798
    a owl:Class .

obo:PATO_0001810
    a owl:Class .

obo:PATO_0001818
    a owl:Class .

obo:PATO_0001819
    a owl:Class .

obo:PATO_0001834
    a owl:Class .

obo:PATO_0001836
    a owl:Class .

obo:PATO_0001851
    a owl:Class .

obo:PATO_0001852
    a owl:Class .

obo:PATO_0001873
    a owl:Class .

obo:PATO_0001912
    a owl:Class .

obo:PATO_0001926
    a owl:Class .

obo:PATO_0001928
    a owl:Class .

obo:PATO_0001930
    a owl:Class .

obo:PATO_0001997
    a owl:Class .

obo:PATO_0002000
    a owl:Class .

obo:PATO_0002001
    a owl:Class .

obo:PATO_0002002
    a owl:Class .

obo:PATO_0002017
    a owl:Class .

obo:PATO_0002051
    a owl:Class .

obo:PATO_0002052
    a owl:Class .

obo:PATO_0002112
    a owl:Class .

obo:PATO_0002247
    a owl:Class .

obo:RO_0000052
    a owl:ObjectProperty ;
    rdfs:subPropertyOf obo:RO_0002314 .

obo:RO_0002295
    a owl:ObjectProperty .

obo:RO_0002314
    a owl:ObjectProperty ;
    owl:propertyChainAxiom (obo:RO_0000052
        obo:BFO_0000050
    ) .

obo:RO_0002503
    a owl:ObjectProperty .

obo:RO_0002573
    a owl:ObjectProperty .

obo:UBERON_0000062
    a owl:Class .

obo:UBERON_0002606
    a owl:Class .

obo:WBPhenotype_0000000
    obo:IAO_0000115 "Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000000" ;
    a owl:Class ;
    rdfs:label "chromosome instability" ;
    rdfs:subClassOf obo:WBPhenotype_0000585 .

obo:WBPhenotype_0000001
    obo:IAO_0000115 "Animals exhibit variations in body posture compared to control animals. For example, in C. elegans characteristic sinusoidal body posture is altered." ;
    oboInOwl:hasNarrowSynonym "body posture abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000001" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "body posture variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 .

obo:WBPhenotype_0000002
    obo:IAO_0000115 "The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000002" ;
    a owl:Class ;
    rdfs:label "kinker" ;
    rdfs:subClassOf obo:WBPhenotype_0004017 .

obo:WBPhenotype_0000003
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0001309 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000003" ;
    a owl:Class ;
    rdfs:label "obsolete flattened locomotion path" ;
    owl:deprecated true .

obo:WBPhenotype_0000004
    obo:IAO_0000115 "Eggs are laid under conditions where egg laying is normally inhibited." ;
    oboInOwl:hasBroadSynonym "Egl c" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000004" ;
    a owl:Class ;
    rdfs:comment "Liquid M9." ;
    rdfs:label "constitutive egg laying" ;
    rdfs:subClassOf obo:WBPhenotype_0000005 .

obo:WBPhenotype_0000005
    obo:IAO_0000115 "Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000005" ;
    a owl:Class ;
    rdfs:label "hyperactive egg laying" ;
    rdfs:subClassOf obo:WBPhenotype_0000640 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000006
    obo:IAO_0000115 "Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control." ;
    oboInOwl:hasBroadSynonym "Egl d" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000006" ;
    a owl:Class ;
    rdfs:label "egg laying defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000640 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001558
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000007
    obo:IAO_0000115 "A worm carcass is formed with retained eggs that hatch inside." ;
    oboInOwl:hasBroadSynonym "Bag" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000007" ;
    a owl:Class ;
    rdfs:label "bag of worms" ;
    rdfs:subClassOf obo:WBPhenotype_0000862 .

obo:WBPhenotype_0000008
    obo:IAO_0000115 "Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasExactSynonym "anaesthetic hypersensitive" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000008" ;
    a owl:Class ;
    rdfs:label "anesthetic hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0000627 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_38867
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000009
    obo:IAO_0000115 "Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasExactSynonym "anaesthetic resistant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000009" ;
    a owl:Class ;
    rdfs:label "anesthetic resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0000627 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_38867
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000010
    obo:IAO_0000115 "Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000010" ;
    a owl:Class ;
    rdfs:label "drug hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_23888
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000011
    obo:IAO_0000115 "Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000011" ;
    a owl:Class ;
    rdfs:label "drug resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_23888
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000012
    obo:IAO_0000115 "Formation of dauer larvae under conditions that do not favor dauer formation." ;
    oboInOwl:hasBroadSynonym "Daf c" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000012" ;
    a owl:Class ;
    rdfs:label "dauer constitutive" ;
    rdfs:subClassOf obo:WBPhenotype_0000637 .

obo:WBPhenotype_0000013
    obo:IAO_0000115 "Failure to form dauer larvae under dauer-inducing conditions." ;
    oboInOwl:hasBroadSynonym "Daf d" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000013" ;
    a owl:Class ;
    rdfs:label "dauer defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000637 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001558
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043053
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000014
    obo:IAO_0000115 "Variations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "cord commissures abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000014" ;
    a owl:Class ;
    rdfs:label "cord commissures variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001226 .

obo:WBPhenotype_0000015
    obo:IAO_0000115 "Variations in the movement towards typically attractive chemicals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000015" ;
    a owl:Class ;
    rdfs:label "positive chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000635 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001558
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000016
    obo:IAO_0000115 "Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasBroadSynonym "Hic" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000016" ;
    a owl:Class ;
    rdfs:label "aldicarb hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000500, obo:WBPhenotype_0000680 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_2555
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000017
    obo:IAO_0000115 "Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasBroadSynonym "Ald R", "Ric" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000017" ;
    a owl:Class ;
    rdfs:label "aldicarb resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000680, obo:WBPhenotype_0001289 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_2555
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000018
    obo:IAO_0000115 "The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000018" ;
    a owl:Class ;
    rdfs:label "pharyngeal pumping increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043050
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000019
    obo:IAO_0000115 "Pharyngeal pumping motion occurs at a slower rate than control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000019" ;
    a owl:Class ;
    rdfs:label "pharyngeal pumping reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043050
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000020
    obo:IAO_0000115 "Pharyngeal pumping motion occurs at intervals that vary from control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000020" ;
    a owl:Class ;
    rdfs:label "pharyngeal pumping irregular" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 .

obo:WBPhenotype_0000021
    obo:IAO_0000115 "Squat animals are dumpy as homozygotes, but roll as heterozygotes." ;
    oboInOwl:hasBroadSynonym "Sqt" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000021" ;
    a owl:Class ;
    rdfs:label "squat" ;
    rdfs:subClassOf obo:WBPhenotype_0000231 .

obo:WBPhenotype_0000022
    obo:IAO_0000115 "Animals are longer than control animals at the same developmental stage." ;
    oboInOwl:hasBroadSynonym "Lon" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000022" ;
    a owl:Class ;
    rdfs:label "long" ;
    rdfs:subClassOf obo:WBPhenotype_0001726 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000573
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000023
    obo:IAO_0000115 "Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000023" ;
    a owl:Class ;
    rdfs:label "serotonin hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_28790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000024
    obo:IAO_0000115 "Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000024" ;
    a owl:Class ;
    rdfs:label "serotonin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_28790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000025
    obo:IAO_0000115 "Fluid-filled blisters appear on the cuticle." ;
    oboInOwl:hasBroadSynonym "Bli" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000025" ;
    a owl:Class ;
    rdfs:label "blistered" ;
    rdfs:subClassOf obo:WBPhenotype_0000948 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001928
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005755
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000026
    obo:IAO_0000115 "Animals are unable to take up or store lipids. In C. elegans, this defect results in pale, skinny and arrested larva." ;
    oboInOwl:hasBroadSynonym "Lpd" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "fat depleted" ;
    oboInOwl:id "WBPhenotype:0000026" ;
    a owl:Class ;
    rdfs:label "lipid depleted" ;
    rdfs:subClassOf obo:WBPhenotype_0001183 .

obo:WBPhenotype_0000027
    obo:IAO_0000115 "Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control." ;
    oboInOwl:hasNarrowSynonym "organism metabolism processing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000027" ;
    a owl:Class ;
    rdfs:label "organism metabolism processing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0000028
    obo:IAO_0000115 "Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control." ;
    oboInOwl:hasNarrowSynonym "RNA processing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000028" ;
    a owl:Class ;
    rdfs:label "RNA processing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006396
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000029
    obo:IAO_0000115 "Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding." ;
    oboInOwl:hasNarrowSynonym "systemic RNAi abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Environmental RNAi defective" ;
    oboInOwl:id "WBPhenotype:0000029" ;
    a owl:Class ;
    rdfs:label "systemic RNAi variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 .

obo:WBPhenotype_0000030
    obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals." ;
    oboInOwl:hasNarrowSynonym "growth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000030" ;
    a owl:Class ;
    rdfs:label "growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040007
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000031
    obo:IAO_0000115 "Any variation that causes a reduction in growth rate compared to control." ;
    oboInOwl:hasBroadSynonym "Gro" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000031" ;
    a owl:Class ;
    rdfs:label "slow growth" ;
    rdfs:subClassOf obo:WBPhenotype_0000043, obo:WBPhenotype_0000438, obo:WBPhenotype_0000676 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040007
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000032
    obo:IAO_0000115 "Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc." ;
    oboInOwl:hasBroadSynonym "Sck" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000032" ;
    a owl:Class ;
    rdfs:label "sick" ;
    rdfs:subClassOf obo:WBPhenotype_0000030 .

obo:WBPhenotype_0000033
    obo:IAO_0000115 "The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000437" ;
    oboInOwl:hasExactSynonym "heterochronic defect" ;
    oboInOwl:hasNarrowSynonym "developmental timing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000033" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:comment "Possible XP GO:0040034." ;
    rdfs:label "developmental timing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040034
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000034
    obo:IAO_0000115 "Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals." ;
    oboInOwl:hasNarrowSynonym "embryonic polarity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000034" ;
    a owl:Class ;
    rdfs:label "embryonic polarity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001769
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBls_0000003
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000035
    obo:IAO_0000115 "Any variation in the overall structure or appearance of the animal as it progresses from hatching to adult compared to control animals." ;
    oboInOwl:hasNarrowSynonym "larval body morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "larval morphology abnormal" ;
    oboInOwl:id "WBPhenotype:0000035" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "larval body morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0000934 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000023
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000036
    obo:IAO_0000115 "Any variation in the overall structure or appearance of the animal after it has completed progression through the larval stages compared to control animals." ;
    oboInOwl:hasNarrowSynonym "adult body morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000036" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "adult body morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0000934 .

obo:WBPhenotype_0000037
    obo:IAO_0000115 "Any variation in the overall structure or appearance of fertilized oocytes that are laid compared to those laid by control animals." ;
    oboInOwl:hasNarrowSynonym "egg morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000037" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "egg morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000934 .

obo:WBPhenotype_0000038
    obo:IAO_0000115 "The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture." ;
    oboInOwl:hasBroadSynonym "Rup" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "burst vulva", "gonad eversion", "gonad exploded through vulva", "rupture through vulva" ;
    oboInOwl:id "WBPhenotype:0000038" ;
    a owl:Class ;
    rdfs:label "exploded through vulva" ;
    rdfs:subClassOf obo:WBPhenotype_0000619 .

obo:WBPhenotype_0000039
    obo:IAO_0000115 "Adult life span is either longer or shorter than typical of control animals." ;
    oboInOwl:hasBroadSynonym "Age" ;
    oboInOwl:hasExactSynonym "life span abnormal", "life span variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "longevity abnormal" ;
    oboInOwl:id "WBPhenotype:0000039" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "life span phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000576 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000050
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000040
    obo:IAO_0000115 "Embryos fail to divide and arrest as one-cell embryos." ;
    oboInOwl:hasBroadSynonym "Emb", "Ocs" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "catastrophic one cell arrest" ;
    oboInOwl:id "WBPhenotype:0000040" ;
    a owl:Class ;
    rdfs:label "one cell arrest early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100 .

obo:WBPhenotype_0000041
    obo:IAO_0000115 "Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control." ;
    oboInOwl:hasNarrowSynonym "osmotic integrity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "osmoregulation variant" ;
    oboInOwl:id "WBPhenotype:0000041" ;
    a owl:Class ;
    rdfs:label "osmotic integrity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030104
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000042
    obo:IAO_0000115 "The progression through stages between fertilization to hatching are temporally retarded." ;
    oboInOwl:hasBroadSynonym "Sle" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000042" ;
    a owl:Class ;
    rdfs:label "slow embryonic development" ;
    rdfs:subClassOf obo:WBPhenotype_0000674, obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000043
    obo:IAO_0000115 "Variations in the progression time of an animal from pronuclei meeting to adulthood compared to control animals." ;
    oboInOwl:hasNarrowSynonym "general pace of development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000043" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "general pace of development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000033 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000161
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0032502
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000044
    obo:IAO_0000115 "Egg is smaller or larger compared to eggs of control animals." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000044" ;
    a owl:Class ;
    rdfs:label "egg size defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002407 .

obo:WBPhenotype_0000045
    obo:IAO_0000115 "The developmental progression of an animal after the embryonic stage, over time, from its formation to its mature structure is delayed compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000045" ;
    a owl:Class ;
    rdfs:label "developmental delay postembryonic" ;
    rdfs:subClassOf obo:WBPhenotype_0000049, obo:WBPhenotype_0000848 .

obo:WBPhenotype_0000046
    obo:IAO_0000115 "More than five minutes between AB and P1 divisions." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pace of P lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000046" ;
    a owl:Class ;
    rdfs:label "pace of P lineage defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000746, obo:WBPhenotype_0000824 .

obo:WBPhenotype_0000047
    obo:IAO_0000115 "Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space." ;
    oboInOwl:hasNarrowSynonym "gastrulation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000047" ;
    a owl:Class ;
    rdfs:label "gastrulation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007369
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000048
    obo:IAO_0000115 "Variations in the ability of an animal to emerge from the protective egg shell compared to control animals." ;
    oboInOwl:hasNarrowSynonym "hatching abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000048" ;
    a owl:Class ;
    rdfs:label "hatching variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035188
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000049
    obo:IAO_0000115 "Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." ;
    oboInOwl:hasNarrowSynonym "postembryonic development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000049" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "postembryonic development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009791
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000050
    obo:IAO_0000115 "Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "egg lethal", "embryonic death", "inviable zygote" ;
    oboInOwl:id "WBPhenotype:0000050" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "embryonic lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000062, obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000003
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000051
    obo:IAO_0000115 "The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal." ;
    oboInOwl:hasBroadSynonym "Emb", "Etv" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000051" ;
    a owl:Class ;
    rdfs:label "embryonic terminal arrest variable emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000063, obo:WBPhenotype_0000749 .

obo:WBPhenotype_0000052
    obo:IAO_0000115 "Lethality caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis." ;
    oboInOwl:hasBroadSynonym "Emb", "Mel" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000052" ;
    a owl:Class ;
    rdfs:label "maternal effect lethal emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000050 .

obo:WBPhenotype_0000053
    obo:IAO_0000115 "Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae." ;
    oboInOwl:hasBroadSynonym "Pat" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "active elongation arrest", "two fold arrest" ;
    oboInOwl:id "WBPhenotype:0000053" ;
    a owl:Class ;
    rdfs:label "paralyzed arrested elongation two fold" ;
    rdfs:subClassOf obo:WBPhenotype_0000050, obo:WBPhenotype_0000494 .

obo:WBPhenotype_0000054
    obo:IAO_0000115 "The animal dies at any time between hatching and onset to adulthood." ;
    oboInOwl:hasBroadSynonym "Let", "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "larval death" ;
    oboInOwl:id "WBPhenotype:0000054" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "larval lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000062 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000023
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000055
    obo:IAO_0000115 "Larvae arrest during early larval development. In C. elegans, this occurs during the L1 or L2 stages of larval development." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000055" ;
    a owl:Class ;
    rdfs:label "early larval arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000059 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#ends_during_or_before> ;
                    owl:someValuesFrom obo:WBls_0000027
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#starts_during_or_after> ;
                    owl:someValuesFrom obo:WBls_0000024
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000056
    obo:IAO_0000115 "Larvae arrest during late larval development. In C. elegans, larval arrest occurs during the L3 or L4 stages of larval development." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000056" ;
    a owl:Class ;
    rdfs:label "late larval arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000059 .

obo:WBPhenotype_0000057
    obo:IAO_0000115 "Animals die during early larval development. In C.elegans, this occurs during the L1- L2 larval stages of the life cycle." ;
    oboInOwl:hasBroadSynonym "Let", "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000057" ;
    a owl:Class ;
    rdfs:label "early larval lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000054 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#ends_during_or_before> ;
                    owl:someValuesFrom obo:WBls_0000027
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#starts_during_or_after> ;
                    owl:someValuesFrom obo:WBls_0000024
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000058
    obo:IAO_0000115 "Animals die during late larval development. In C. elegans, this occurs during the L3- L4 larval stages of the life cycle." ;
    oboInOwl:hasBroadSynonym "Let", "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000058" ;
    a owl:Class ;
    rdfs:label "late larval lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000054 .

obo:WBPhenotype_0000059
    obo:IAO_0000115 "The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." ;
    oboInOwl:hasBroadSynonym "Lva" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000059" ;
    a owl:Class ;
    rdfs:label "larval arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000750, obo:WBPhenotype_0001016 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000060
    obo:IAO_0000115 "Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background." ;
    oboInOwl:hasBroadSynonym "Adl", "Let" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000060" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "adult lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000062 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000041
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000061
    obo:IAO_0000115 "The duration of viability in the adult phase of the life-cycle surpasses that of control animals." ;
    oboInOwl:hasBroadSynonym "Age" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "life span increased", "longevity increased" ;
    oboInOwl:id "WBPhenotype:0000061" ;
    a owl:Class ;
    rdfs:label "extended life span" ;
    rdfs:subClassOf obo:WBPhenotype_0000039 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001603
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000062
    obo:IAO_0000115 "Animals die prematurely at any stage of the life cycle." ;
    oboInOwl:hasBroadSynonym "Let" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000062" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000063
    obo:IAO_0000115 "Variations that cause developmental progression to cease at different stages of the lifecycle." ;
    oboInOwl:hasBroadSynonym "Var" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000063" ;
    a owl:Class ;
    rdfs:label "terminal arrest variable" ;
    rdfs:subClassOf obo:WBPhenotype_0000062 .

obo:WBPhenotype_0000064
    obo:IAO_0000115 "Animals die prematurely at any stage of the life cycle in a sex dependent manner." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Let" ;
    oboInOwl:id "WBPhenotype:0000064" ;
    a owl:Class ;
    rdfs:label "sexually dimorphic lethality" ;
    rdfs:subClassOf obo:WBPhenotype_0000062 .

obo:WBPhenotype_0000065
    obo:IAO_0000115 "XO-bearing individuals die preferentially over other animals in the population. In C.elegans, X0 animals die preferentially over XX animals." ;
    oboInOwl:hasBroadSynonym "Let" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "male specific lethality" ;
    oboInOwl:id "WBPhenotype:0000065" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "X0 lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000064 .

obo:WBPhenotype_0000066
    obo:IAO_0000115 "XX-bearing individuals die preferentially over other animals in the population. In C.elegans, XX animals die preferentially over X0 animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "hermaphrodite specific lethality" ;
    oboInOwl:id "WBPhenotype:0000066" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "XX lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000064 .

obo:WBPhenotype_0000067
    obo:IAO_0000115 "Animals exhibit variations in response to stress stimuli compared to control animals." ;
    oboInOwl:hasNarrowSynonym "organism stress response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000067" ;
    a owl:Class ;
    rdfs:label "organism stress response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006950
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000068
    obo:IAO_0000115 "Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control." ;
    oboInOwl:hasNarrowSynonym "oxidative stress response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000068" ;
    a owl:Class ;
    rdfs:label "cellular oxidative stress response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0034599
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000069
    obo:IAO_0000115 "Any variation in the progression of the progeny of an animal at any time from its fertilization to adulthood compared to control." ;
    oboInOwl:hasNarrowSynonym "progeny abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000069" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "progeny variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 .

obo:WBPhenotype_0000070
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in control males. In C. elegans, this region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan." ;
    oboInOwl:hasBroadSynonym "Mab" ;
    oboInOwl:hasNarrowSynonym "male tail morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000070" ;
    a owl:Class ;
    rdfs:label "male tail morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000073, obo:WBPhenotype_0001024 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005741
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0007850
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000071
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any portion of their anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring) compared to control." ;
    oboInOwl:hasNarrowSynonym "head morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000071" ;
    a owl:Class ;
    rdfs:label "head morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000582 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005739
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000072
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000072" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "body morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000582 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005740
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000073
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any portion of the most posterior region of the body compared to control. The anterior bound of the tail is not well defined though it might range from the position of the post-deirids to the opening of the anus (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "tail morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000073" ;
    a owl:Class ;
    rdfs:label "tail morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000582 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005741
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000074
    obo:IAO_0000115 "Any variation in the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control." ;
    oboInOwl:hasNarrowSynonym "genetic pathway abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000074" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "genetic pathway variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000576 .

obo:WBPhenotype_0000075
    obo:IAO_0000115 "Any variation in the attachment of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) to the outer body of an animal compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "cuticle attachment abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000075" ;
    a owl:Class ;
    rdfs:label "cuticle attachment variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000201 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000076
    obo:IAO_0000115 "Variations in the adhesion of the layer of cells that cover the external surface of an organism which serves to protect the animal from external environment compared to control." ;
    oboInOwl:hasNarrowSynonym "epithelial attachment abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "hypodermal attachment abnormal" ;
    oboInOwl:id "WBPhenotype:0000076" ;
    a owl:Class ;
    rdfs:label "epithelial attachment variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000608 .

obo:WBPhenotype_0000077
    obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement." ;
    oboInOwl:hasNarrowSynonym "cuticle shedding abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000077" ;
    a owl:Class ;
    rdfs:label "cuticle shedding defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000638 .

obo:WBPhenotype_0000078
    obo:IAO_0000115 "The hypodermal cells, which lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, are misplaced such that they are stacked along the dorsal-ventral axis rather than forming a continuous row of adjacent cells ." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000078" ;
    a owl:Class ;
    rdfs:label "seam cells stacked" ;
    rdfs:subClassOf obo:WBPhenotype_0000703 .

obo:WBPhenotype_0000079
    obo:IAO_0000115 "The small linear ridges running along the lateral lines of the cuticle of adults are branched as opposed to having an unbiforcated arrangement, lengthwise along the body (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000079" ;
    a owl:Class ;
    rdfs:label "branched adult alae" ;
    rdfs:subClassOf obo:WBPhenotype_0001412 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000402
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007832
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000080
    obo:IAO_0000115 "Animals lack the anterior portion of the pharynx." ;
    oboInOwl:hasBroadSynonym "Aph" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000080" ;
    a owl:Class ;
    rdfs:label "no anterior pharynx" ;
    rdfs:subClassOf obo:WBPhenotype_0000115, obo:WBPhenotype_0001646 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003733
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000081
    obo:IAO_0000115 "The developmental program of the animals does not continue past the first larval stage (L1)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000081" ;
    a owl:Class ;
    rdfs:label "L1 arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000055, obo:WBPhenotype_0000751 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000024
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000082
    obo:IAO_0000115 "The developmental program of the animals does not continue past the second larval stage (L2)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000082" ;
    a owl:Class ;
    rdfs:label "L2 arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000055, obo:WBPhenotype_0000752, obo:WBPhenotype_0001019 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000027
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000083
    obo:IAO_0000115 "The developmental program of the animals does not continue past the third larval stage (L3)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000083" ;
    a owl:Class ;
    rdfs:label "L3 arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000056, obo:WBPhenotype_0000753, obo:WBPhenotype_0001019 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000035
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000084
    obo:IAO_0000115 "The developmental program of the animals does not continue past the fourth larval stage (L4)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000084" ;
    a owl:Class ;
    rdfs:label "L4 arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000056, obo:WBPhenotype_0000754 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000038
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000085
    obo:IAO_0000115 "The intestinal lumen is expanded and can often be shown to be filled with bacteria. This swelling is distinct from distension of the entire intestine (intestinal edema)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000085" ;
    a owl:Class ;
    rdfs:label "swollen intestinal lumen" ;
    rdfs:subClassOf obo:WBPhenotype_0000710 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001851
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005772
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000086
    obo:IAO_0000115 "Intestine is shrunken and may appear constricted." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000086" ;
    a owl:Class ;
    rdfs:label "shrunken intestine" ;
    rdfs:subClassOf obo:WBPhenotype_0000710 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000585
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005772
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000087
    obo:IAO_0000115 "Any variation in the progression of a body wall muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "body wall cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "body wall muscle cell development abnormal" ;
    oboInOwl:id "WBPhenotype:0000087" ;
    a owl:Class ;
    rdfs:label "body wall cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000815 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006804
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000088
    obo:IAO_0000115 "The arrangement of the principal muscle cell type whose contractile activity generates body motion in the nematode differs from that observed in control animals. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "body wall muscle displaced" ;
    oboInOwl:id "WBPhenotype:0000088" ;
    a owl:Class ;
    rdfs:label "body muscle displaced" ;
    rdfs:subClassOf obo:WBPhenotype_0000861 .

obo:WBPhenotype_0000089
    obo:IAO_0000115 "Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000089" ;
    a owl:Class ;
    rdfs:label "alpha amanitin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_37415
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000090
    obo:IAO_0000115 "Animals are deficient in the adhesion of the cuticle to the epidermal surface of the animal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "hypodermis detached from cuticle" ;
    oboInOwl:id "WBPhenotype:0000090" ;
    a owl:Class ;
    rdfs:label "epidermis cuticle detached" ;
    rdfs:subClassOf obo:WBPhenotype_0000075, obo:WBPhenotype_0000076 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001453
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:WBbt_0005755
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005733
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000091
    obo:IAO_0000115 "The cell(s) whose principal function is to provide contractile forces, is separated from the adjacent epidermis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "hypodermis detached from muscle" ;
    oboInOwl:id "WBPhenotype:0000091" ;
    a owl:Class ;
    rdfs:label "epidermis muscle detached" ;
    rdfs:subClassOf obo:WBPhenotype_0000076, obo:WBPhenotype_0000474 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001453
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:WBbt_0003675
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005733
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000092
    obo:IAO_0000115 "Any variation in the processes that govern the expansion of intestinal cell populations compared to control." ;
    oboInOwl:hasNarrowSynonym "intestinal cell proliferation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000092" ;
    a owl:Class ;
    rdfs:label "intestinal cell proliferation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000705 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008283
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005792
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000093
    obo:IAO_0000115 "The descendants of a particular precursor cell exhibit variations in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasBroadSynonym "Lin" ;
    oboInOwl:hasNarrowSynonym "lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000093" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 .

obo:WBPhenotype_0000094
    obo:IAO_0000115 "Any variation in the progression of the caudal opening of the rectum in the tail over time compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "anus development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000094" ;
    a owl:Class ;
    rdfs:label "anus development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000617 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005364
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000095
    obo:IAO_0000115 "The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals.  In C. elegans the M lineage is a postembryonic mesodermal lineage." ;
    oboInOwl:hasNarrowSynonym "M lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000095" ;
    a owl:Class ;
    rdfs:label "M lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0008439
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000096
    obo:IAO_0000115 "Variations in the progression of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) over time compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "cloacal development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000096" ;
    a owl:Class ;
    rdfs:label "cloacal development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000617 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005774
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000097
    obo:IAO_0000115 "The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "AB lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000097" ;
    a owl:Class ;
    rdfs:label "AB lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000824 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0008611
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000098
    obo:IAO_0000115 "Any variation in the progression of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine over time compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "pharyngeal intestinal valve development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000098" ;
    a owl:Class ;
    rdfs:label "pharyngeal intestinal valve development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000617 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005767
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000099
    obo:IAO_0000115 "The descendants of any of the P precursor cells exhibit variations in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "P lineages abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000099" ;
    a owl:Class ;
    rdfs:label "P lineages variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0008590
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000100
    obo:IAO_0000115 "Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "cell UV response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000100" ;
    a owl:Class ;
    rdfs:label "cell UV response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0034644
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000101
    obo:IAO_0000115 "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, UV irradiation, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000101" ;
    a owl:Class ;
    rdfs:label "UV induced apoptosis increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000100, obo:WBPhenotype_0000183 .

obo:WBPhenotype_0000102
    obo:IAO_0000115 "Animals display variations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "presynaptic vesicle cluster abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "synaptic vesicle cluster abnormal" ;
    oboInOwl:id "WBPhenotype:0000102" ;
    a owl:Class ;
    rdfs:label "presynaptic vesicle cluster variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001321 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0097091
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000103
    obo:IAO_0000115 "Any variation in the progression of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes over time compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "gut granule development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000103" ;
    a owl:Class ;
    rdfs:label "gut granule development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000705 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:GO_0044840
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000104
    obo:IAO_0000115 "Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell." ;
    oboInOwl:hasNarrowSynonym "cell polarity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000104" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell polarity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007163
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000105
    obo:IAO_0000115 "Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly." ;
    oboInOwl:hasBroadSynonym "Oma" ;
    oboInOwl:hasNarrowSynonym "oocyte meiotic maturation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000105" ;
    a owl:Class ;
    rdfs:label "oocyte meiotic maturation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000313 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1903537
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000106
    obo:IAO_0000115 "Variations in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal compared to control animals." ;
    oboInOwl:hasNarrowSynonym "inhibition of oocyte maturation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000106" ;
    a owl:Class ;
    rdfs:label "inhibition of oocyte maturation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000105 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1904145
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000107
    obo:IAO_0000115 "Any variation that alters the control mechanisms that inhibit oocyte maturation and release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control." ;
    oboInOwl:hasNarrowSynonym "inhibition of ovulation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000107" ;
    a owl:Class ;
    rdfs:label "inhibition of ovulation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000666 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060280
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000108
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0000583 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000108" ;
    a owl:Class ;
    rdfs:label "obsolete severe dumpy" ;
    owl:deprecated true .

obo:WBPhenotype_0000109
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0000583 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000109" ;
    a owl:Class ;
    rdfs:label "obsolete moderate dumpy" ;
    owl:deprecated true .

obo:WBPhenotype_0000110
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0000583 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000110" ;
    a owl:Class ;
    rdfs:label "obsolete slightly dumpy" ;
    owl:deprecated true .

obo:WBPhenotype_0000111
    obo:IAO_0000115 "Any variation in the cellular or subcellular distribution of a gene product compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "pattern of gene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000111" ;
    a owl:Class ;
    rdfs:label "pattern of gene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0000112
    obo:IAO_0000115 "Variations in the biogenesis and stability of protein molecules compared to control." ;
    oboInOwl:hasNarrowSynonym "protein expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000112" ;
    a owl:Class ;
    rdfs:label "protein expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0000113
    obo:IAO_0000115 "Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control." ;
    oboInOwl:hasNarrowSynonym "RNA expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000113" ;
    a owl:Class ;
    rdfs:label "RNA expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0000114
    obo:IAO_0000115 "Variations in the biogenesis and stability of messenger RNA molecules compared to control." ;
    oboInOwl:hasNarrowSynonym "mRNA expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000114" ;
    a owl:Class ;
    rdfs:label "mRNA expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0000115
    obo:IAO_0000115 "Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb)." ;
    oboInOwl:hasNarrowSynonym "anterior pharynx abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000115" ;
    a owl:Class ;
    rdfs:label "anterior pharynx variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000707 .

obo:WBPhenotype_0000116
    obo:IAO_0000115 "Animals die in between the early and late larval stages. In C. elegans, this occurs during the L2- L3 larval stages of the life cycle." ;
    oboInOwl:hasBroadSynonym "Let", "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000116" ;
    a owl:Class ;
    rdfs:label "mid larval lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000054 .

obo:WBPhenotype_0000117
    obo:IAO_0000115 "Animals die at the L1 stage of the life cycle." ;
    oboInOwl:hasBroadSynonym "Let", "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000117" ;
    a owl:Class ;
    rdfs:label "L1 lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000057 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000024
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000118
    obo:IAO_0000115 "L2 lethal: Animals die at the L2 stage of the life cycle." ;
    oboInOwl:hasBroadSynonym "Let", "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000118" ;
    a owl:Class ;
    rdfs:label "L2 lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000057, obo:WBPhenotype_0000116 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000027
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000119
    obo:IAO_0000115 "Any change that results in higher than normal levels of protein expression compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000119" ;
    a owl:Class ;
    rdfs:label "protein expression increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001400 .

obo:WBPhenotype_0000120
    obo:IAO_0000115 "Any change that results in lower than normal levels of protein expression compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000120" ;
    a owl:Class ;
    rdfs:label "protein expression reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001400 .

obo:WBPhenotype_0000121
    obo:IAO_0000115 "Variations in the chemical reactions and pathways resulting in the formation of a protein, compared to control." ;
    oboInOwl:hasNarrowSynonym "translation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "protein synthesis abnormal" ;
    oboInOwl:id "WBPhenotype:0000121" ;
    a owl:Class ;
    rdfs:label "translation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000112 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006412
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000122
    obo:IAO_0000115 "Any variation in the posttranslational modification of a protein (which may include cleavage of peptide bonds) leading to the attainment of the full functional capacity of the protein compared to control." ;
    oboInOwl:hasNarrowSynonym "post translational processing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "protein processing variant" ;
    oboInOwl:id "WBPhenotype:0000122" ;
    a owl:Class ;
    rdfs:label "post translational processing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0000123
    obo:IAO_0000115 "Variations that cause a decrease in the expression level of a biological catalyst, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000123" ;
    a owl:Class ;
    rdfs:label "enzyme expression level reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000120 .

obo:WBPhenotype_0000124
    obo:IAO_0000115 "Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000124" ;
    a owl:Class ;
    rdfs:label "enzyme activity reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000727 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0003824
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000125
    obo:IAO_0000115 "Any variation that results in an increase in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000125" ;
    a owl:Class ;
    rdfs:label "enzyme activity increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000727 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0003824
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000126
    obo:IAO_0000115 "Variations in the time from pronuclei meeting to furrow initiation during the first cell division compared to control animals." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "general pace of development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000126" ;
    a owl:Class ;
    rdfs:label "general pace of development defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000043 .

obo:WBPhenotype_0000127
    obo:IAO_0000115 "Characteristic exit from the dauer stage is altered compared to control animals." ;
    oboInOwl:hasNarrowSynonym "dauer recovery abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000127" ;
    a owl:Class ;
    rdfs:label "dauer recovery variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000308 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043054
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000128
    obo:IAO_0000115 "Animals are more likely to form dauers at temperatures that do not induce dauer entry in control animals." ;
    oboInOwl:hasBroadSynonym "Hid" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000128" ;
    a owl:Class ;
    rdfs:label "temperature induced dauer formation increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000639 .

obo:WBPhenotype_0000129
    obo:IAO_0000115 "Animals do not enter dauer at a temperature that induces dauer formation in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000129" ;
    a owl:Class ;
    rdfs:label "temperature induced dauer formation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000013, obo:WBPhenotype_0000639 .

obo:WBPhenotype_0000130
    obo:IAO_0000115 "Animals enter the dauer stage when exposed to lower concentrations or shorter exposure times of chemicals that induce dauer formation compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000130" ;
    a owl:Class ;
    rdfs:label "pheromone induced dauer formation enhanced" ;
    rdfs:subClassOf obo:WBPhenotype_0000132 .

obo:WBPhenotype_0000131
    obo:IAO_0000115 "Animals do not enter dauer when exposed to chemicals that induce dauer formation in control animals." ;
    oboInOwl:hasBroadSynonym "Phd" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000131" ;
    a owl:Class ;
    rdfs:label "pheromone induced dauer formation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000013, obo:WBPhenotype_0000132 .

obo:WBPhenotype_0000132
    obo:IAO_0000115 "Animals exhibit variations in the entry into the dauer stage when exposed to concentrations of chemicals that induce dauer formation in control animals." ;
    oboInOwl:hasNarrowSynonym "pheromone induced dauer formation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000132" ;
    a owl:Class ;
    rdfs:label "pheromone induced dauer formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001539 .

obo:WBPhenotype_0000133
    obo:IAO_0000115 "The levels of an enzyme involved in the manufacture of lipids are decreased compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000133" ;
    a owl:Class ;
    rdfs:label "expression lipogenic enzyme reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000123 .

obo:WBPhenotype_0000134
    obo:IAO_0000115 "Animals exhibit a decrease in the intensity of expression of a gene product compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000134" ;
    a owl:Class ;
    rdfs:label "gene expression level reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0002575 .

obo:WBPhenotype_0000135
    obo:IAO_0000115 "Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000135" ;
    a owl:Class ;
    rdfs:label "gene expression level high" ;
    rdfs:subClassOf obo:WBPhenotype_0002575 .

obo:WBPhenotype_0000136
    obo:IAO_0000115 "Animals exhibit elevated levels of messenger RNA compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000136" ;
    a owl:Class ;
    rdfs:label "mRNA levels increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000114 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_33699
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000137
    obo:IAO_0000115 "Animals exhibit decreased levels of messenger RNA compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000137" ;
    a owl:Class ;
    rdfs:label "mRNA levels reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000114 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_33699
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000138
    obo:IAO_0000115 "The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals." ;
    oboInOwl:hasNarrowSynonym "lipid composition abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "fat composition abnormal", "fatty acid composition abnormal" ;
    oboInOwl:id "WBPhenotype:0000138" ;
    a owl:Class ;
    rdfs:label "lipid composition variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000725 .

obo:WBPhenotype_0000139
    obo:IAO_0000115 "Animals exhibit variations in survival when exposed to stress stimuli that induce lethality in control animals." ;
    oboInOwl:hasNarrowSynonym "stress induced lethality abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000139" ;
    a owl:Class ;
    rdfs:label "stress induced lethality variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 .

obo:WBPhenotype_0000140
    obo:IAO_0000115 "Animals exhibit variations in cessation of development when exposed to stress stimuli that induce developmental arrest in control animals." ;
    oboInOwl:hasNarrowSynonym "stress induced arrest abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000140" ;
    a owl:Class ;
    rdfs:label "stress induced arrest variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 .

obo:WBPhenotype_0000141
    obo:IAO_0000115 "Animal populations exhibit a further decrease in survival when exposed to stress stimuli compared to the lethality rate observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000141" ;
    a owl:Class ;
    rdfs:label "stress induced lethality increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000139 .

obo:WBPhenotype_0000142
    obo:IAO_0000115 "Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ;
    oboInOwl:hasNarrowSynonym "cell stress response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000142" ;
    a owl:Class ;
    rdfs:label "cell stress response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000585 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0033554
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000143
    obo:IAO_0000115 "Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism UV response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000143" ;
    a owl:Class ;
    rdfs:label "organism UV response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009411
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000144
    obo:IAO_0000115 "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000144" ;
    a owl:Class ;
    rdfs:label "pathogen induced cell death increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0001269 .

obo:WBPhenotype_0000145
    obo:IAO_0000115 "Animals exhibit variations in the time of onset or duration of the fertile period, or production of new individuals that contain some portion of their genetic material inherited from that organism compared to control." ;
    oboInOwl:hasExactSynonym "fertility variant" ;
    oboInOwl:hasNarrowSynonym "fertility abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000145" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "fertility phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000613 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000274
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000146
    obo:IAO_0000115 "Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins or changes in life span." ;
    oboInOwl:hasNarrowSynonym "organism temperature response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000146" ;
    a owl:Class ;
    rdfs:label "organism temperature response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009266
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000147
    obo:IAO_0000115 "Any variation in the state or activity of an organism as a result of deprivation of nourishment, compared to control." ;
    oboInOwl:hasNarrowSynonym "organism starvation response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000147" ;
    a owl:Class ;
    rdfs:label "organism starvation response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042594
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000148
    obo:IAO_0000115 "Animals exhibit variations in the entry into the dauer stage when exposed to nutrient poor conditions that induce dauer formation in control animals." ;
    oboInOwl:hasNarrowSynonym "starvation induced dauer formation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000148" ;
    a owl:Class ;
    rdfs:label "starvation induced dauer formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000147, obo:WBPhenotype_0001539 .

obo:WBPhenotype_0000149
    obo:IAO_0000115 "Animals are more likely to form dauers under nutrient conditions that do not induce dauer entry in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000149" ;
    a owl:Class ;
    rdfs:label "starvation induced dauer formation increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000148 .

obo:WBPhenotype_0000150
    obo:IAO_0000115 "Animals do not enter dauer under nutrient-poor conditions that induce dauer formation in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000150" ;
    a owl:Class ;
    rdfs:label "starvation induced dauer formation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000013, obo:WBPhenotype_0000148 .

obo:WBPhenotype_0000151
    obo:IAO_0000115 "Embryos generate an excess number of anterior derived pharyngeal cells. In C. elegans, embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere." ;
    oboInOwl:hasBroadSynonym "Apx" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000151" ;
    a owl:Class ;
    rdfs:label "anterior pharynx extra cells" ;
    rdfs:subClassOf obo:WBPhenotype_0000115, obo:WBPhenotype_0002175 .

obo:WBPhenotype_0000152
    obo:IAO_0000115 "One-cell embryos do not form the shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000152" ;
    a owl:Class ;
    rdfs:label "no cleavage furrow first division early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001129 .

obo:WBPhenotype_0000153
    obo:IAO_0000115 "Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals." ;
    oboInOwl:hasExactSynonym "body wall contraction variant" ;
    oboInOwl:hasNarrowSynonym "body wall contraction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000153" ;
    a owl:Class ;
    rdfs:label "body wall muscle contraction abnormal" ;
    rdfs:subClassOf obo:WBPhenotype_0000596 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0006936
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005813
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000154
    obo:IAO_0000115 "The characteristic number of offspring produced is lower compared to that of control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000154" ;
    a owl:Class ;
    rdfs:label "reduced brood size" ;
    rdfs:subClassOf obo:WBPhenotype_0000673 .

obo:WBPhenotype_0000155
    obo:IAO_0000115 "Contents or structures of the cell are oriented on the opposite side of the cell compared to control animals; In C. elegans, this can result in the fate pattern of descendants being flipped." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000155" ;
    a owl:Class ;
    rdfs:label "cell polarity reversed" ;
    rdfs:subClassOf obo:WBPhenotype_0000104 .

obo:WBPhenotype_0000156
    obo:IAO_0000115 "Any variation in the time interval between successive contractions of the body wall muscles during the defecation motor program compared to cantrol." ;
    oboInOwl:hasNarrowSynonym "body wall contraction interval abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "body wall muscle contraction interval abnormal" ;
    oboInOwl:id "WBPhenotype:0000156" ;
    a owl:Class ;
    rdfs:label "body wall muscle contraction interval during defecation abnormal" ;
    rdfs:subClassOf obo:WBPhenotype_0000210 .

obo:WBPhenotype_0000157
    obo:IAO_0000115 "Animals exhibit variations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle compared to control animals." ;
    oboInOwl:hasBroadSynonym "pBoc" ;
    oboInOwl:hasNarrowSynonym "posterior body wall contraction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "posterior body contraction abnormal", "posterior body wall contraction defective" ;
    oboInOwl:id "WBPhenotype:0000157" ;
    a owl:Class ;
    rdfs:label "posterior body wall contraction defecation cycle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000210 .

obo:WBPhenotype_0000158
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000209 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000158" ;
    a owl:Class ;
    rdfs:label "obsolete posterior body wall shortened interval" ;
    owl:deprecated true .

obo:WBPhenotype_0000159
    obo:IAO_0000115 "OBSOLETE: Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas)." ;
    obo:IAO_0100001 obo:WBPhenotype_0000308 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000159" ;
    a owl:Class ;
    rdfs:label "obsolete dauer arrest variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000160
    obo:IAO_0000115 "Embryos do not form a defined shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000160" ;
    a owl:Class ;
    rdfs:label "cleavage furrow not discrete early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001129 .

obo:WBPhenotype_0000161
    obo:IAO_0000115 "Any variation in the rotation of centrosomes and associated pronuclei in one-cell embryo, occurring as a transition between pronuclear migration and pronuclear fusion compared to control." ;
    oboInOwl:hasNarrowSynonym "nuclear rotation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000161" ;
    a owl:Class ;
    rdfs:label "nuclear rotation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001599
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005634
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000162
    obo:IAO_0000115 "Larva show deficiencies in chroma resulting in increased translucency." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "translucent" ;
    oboInOwl:id "WBPhenotype:0000162" ;
    a owl:Class ;
    rdfs:label "pale larva" ;
    rdfs:subClassOf obo:WBPhenotype_0000890, obo:WBPhenotype_0001261 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000328
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000023
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000163
    obo:IAO_0000115 "Larva appear unusually transparent when compared to control." ;
    oboInOwl:hasBroadSynonym "Clr" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "transparent" ;
    oboInOwl:id "WBPhenotype:0000163" ;
    a owl:Class ;
    rdfs:label "clear larva" ;
    rdfs:subClassOf obo:WBPhenotype_0000890, obo:WBPhenotype_0001010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000964
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000023
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000164
    obo:IAO_0000115 "Animals exhibit a reduced girth compared to a control animal of the same developmental stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "decreased girth", "slim" ;
    oboInOwl:id "WBPhenotype:0000164" ;
    a owl:Class ;
    rdfs:label "thin" ;
    rdfs:subClassOf obo:WBPhenotype_0001727 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000592
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000165
    obo:IAO_0000115 "Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing." ;
    oboInOwl:hasNarrowSynonym "cell fusion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000165" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell fusion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000768
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000166
    obo:IAO_0000115 "Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation." ;
    oboInOwl:hasNarrowSynonym "seam cell fusion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000166" ;
    a owl:Class ;
    rdfs:label "seam cell fusion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000165 .

obo:WBPhenotype_0000167
    obo:IAO_0000115 "Seam cells fuse to form a continuous syncytium along the body wall at an earlier stage of development compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000167" ;
    a owl:Class ;
    rdfs:label "precocious seam cell fusion" ;
    rdfs:subClassOf obo:WBPhenotype_0000166, obo:WBPhenotype_0001433 .

obo:WBPhenotype_0000168
    obo:IAO_0000115 "Variations in the regulated release of proteins needed for alae formation by epidermal seam cells compared to control. Alae are small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (WormAtlas)." ;
    oboInOwl:hasNarrowSynonym "alae secretion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "alae formation variant" ;
    oboInOwl:id "WBPhenotype:0000168" ;
    a owl:Class ;
    rdfs:label "alae secretion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000258 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0046903
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0007832
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000169
    obo:IAO_0000115 "Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000169" ;
    a owl:Class ;
    rdfs:label "early exit cell cycle" ;
    rdfs:subClassOf obo:WBPhenotype_0001995 .

obo:WBPhenotype_0000170
    obo:IAO_0000115 "Formation of alae occurs earlier in development compared to control animals; In C. elegans, adult lateral alae are typically generated during the late L4 stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000170" ;
    a owl:Class ;
    rdfs:label "precocious alae" ;
    rdfs:subClassOf obo:WBPhenotype_0000168, obo:WBPhenotype_0000439 .

obo:WBPhenotype_0000171
    obo:IAO_0000115 "Any aberrancy in the processes that govern expansion of cell populations compared to control animals." ;
    oboInOwl:hasNarrowSynonym "cell proliferation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000171" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell proliferation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008283
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000172
    obo:IAO_0000115 "The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are increased." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000172" ;
    a owl:Class ;
    rdfs:label "cell proliferation increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000171 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008283
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000173
    obo:IAO_0000115 "The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000173" ;
    a owl:Class ;
    rdfs:label "cell proliferation reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000171 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002052
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008283
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000174
    obo:IAO_0000115 "Any variation in the progression of the layer of connective tissue over the surface of tissues that serves to separate it from neighboring tissues, from its formation to its mature structure compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "basal lamina development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000174" ;
    a owl:Class ;
    rdfs:label "basal lamina development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000619 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005756
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000175
    obo:IAO_0000115 "Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000175" ;
    a owl:Class ;
    rdfs:label "hypercontracted" ;
    rdfs:subClassOf obo:WBPhenotype_0000001 .

obo:WBPhenotype_0000176
    obo:IAO_0000115 "Any variation in the specific actions or reactions of an animal after completion of feeding, typically after a fast, compared to that observed in control animals. In C. elegans worms become behaviorally quiescent and cease feeding and moving when sated." ;
    oboInOwl:hasNarrowSynonym "satiety behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000176" ;
    a owl:Class ;
    rdfs:label "satiety behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000659 .

obo:WBPhenotype_0000177
    obo:IAO_0000115 "Any variation that results in a decrease of acetylcholine esterase levels, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000177" ;
    a owl:Class ;
    rdfs:label "acetylcholinesterase reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000124 .

obo:WBPhenotype_0000178
    obo:IAO_0000115 "Cells are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000178" ;
    a owl:Class ;
    rdfs:label "cell degeneration" ;
    rdfs:subClassOf obo:WBPhenotype_0000729 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000639
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004017
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000179
    obo:IAO_0000115 "Cells specialized for receiving, conducting and transmitting impulses in the nervous system are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000179" ;
    a owl:Class ;
    rdfs:label "neuron degeneration" ;
    rdfs:subClassOf obo:WBPhenotype_0000178 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000639
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003679
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000180
    obo:IAO_0000115 "Animals display variations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "axon morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000180" ;
    a owl:Class ;
    rdfs:label "axon morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001398 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030424
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000181
    obo:IAO_0000115 "Animals display variations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in control animals." ;
    oboInOwl:hasNarrowSynonym "axon trajectory abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000181" ;
    a owl:Class ;
    rdfs:label "axon trajectory variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000180 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000133
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030424
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000182
    obo:IAO_0000115 "Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000182" ;
    a owl:Class ;
    rdfs:label "apoptosis reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002052
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006915
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000183
    obo:IAO_0000115 "Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000183" ;
    a owl:Class ;
    rdfs:label "apoptosis increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006915
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000184
    obo:IAO_0000115 "Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000184" ;
    a owl:Class ;
    rdfs:label "apoptosis fails to occur" ;
    rdfs:subClassOf obo:WBPhenotype_0000182 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006915
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000185
    obo:IAO_0000115 "Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000185" ;
    a owl:Class ;
    rdfs:label "apoptosis protracted" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBPhenotype_0000186
    obo:IAO_0000115 "Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000896" ;
    oboInOwl:hasExactSynonym "oocyte germ cell differentiation abnormal" ;
    oboInOwl:hasNarrowSynonym "oogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "oocyte development abnormal" ;
    oboInOwl:id "WBPhenotype:0000186" ;
    a owl:Class ;
    rdfs:label "oogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000894 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048599
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000187
    obo:IAO_0000115 "The overall structure or appearance of fertilized oocytes that are laid has every part of their surface equidistant from the center." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000187" ;
    a owl:Class ;
    rdfs:label "egg round" ;
    rdfs:subClassOf obo:WBPhenotype_0000373 .

obo:WBPhenotype_0000188
    obo:IAO_0000115 "Any variation in the 'arm-like' form, structure or composition of the specialized tissue of the reproductive tract that produces gametes compared to control. In C. elegans the reproductive tract in the hermaphrodite has two equivalent gonad 'arms', while the male has a one-armed gonad." ;
    oboInOwl:hasNarrowSynonym "gonad arm morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000188" ;
    a owl:Class ;
    rdfs:label "gonad arm morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000977 .

obo:WBPhenotype_0000189
    obo:IAO_0000115 "Hypodermal cells fail to be organized in the same manner as observed in control animals. In C. elegans, hypodermal cells typically organize into distinct dorsal, lateral and ventral rows and cover the entire body." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000189" ;
    a owl:Class ;
    rdfs:label "hypodermis disorganized" ;
    rdfs:subClassOf obo:WBPhenotype_0000703 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000937
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005733
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000190
    obo:IAO_0000115 "Animals fail to exit from the facultative diapause of the dauer larval stage of nematode development." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000190" ;
    a owl:Class ;
    rdfs:label "no dauer recovery" ;
    rdfs:subClassOf obo:WBPhenotype_0000127 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043054
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000191
    obo:IAO_0000115 "Animals exhibit variations in their response to a situation when there is too high a density of nematodes to be supported by the available amount of food and space compared to that observed in control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "organism crowding response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000191" ;
    a owl:Class ;
    rdfs:label "organism crowding response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0090664
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000192
    obo:IAO_0000115 "Any variation that results in the misregulation of enzymatic activity such that catalysis occurs at a constant rate regardless of physiological demand or the concentration of a substrate." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000192" ;
    a owl:Class ;
    rdfs:label "constitutive enzyme activity" ;
    rdfs:subClassOf obo:WBPhenotype_0000125 .

obo:WBPhenotype_0000193
    obo:IAO_0000115 "Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000193" ;
    a owl:Class ;
    rdfs:label "dominant negative enzyme" ;
    rdfs:subClassOf obo:WBPhenotype_0000727 .

obo:WBPhenotype_0000194
    obo:IAO_0000115 "Variations in the placement of the polar body formed in the first division of meiosis of a primary oocyte, compared to control. A polar body is the by-product of meiosis (destined to degenerate) in female or hermaphrodite animals." ;
    oboInOwl:hasNarrowSynonym "first polar body position abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000194" ;
    a owl:Class ;
    rdfs:label "first polar body position variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000775 .

obo:WBPhenotype_0000195
    obo:IAO_0000115 "Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern." ;
    oboInOwl:hasNarrowSynonym "distal tip cell migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "DTC migration abnormal" ;
    oboInOwl:id "WBPhenotype:0000195" ;
    a owl:Class ;
    rdfs:label "distal tip cell migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000594 .

obo:WBPhenotype_0000196
    obo:IAO_0000115 "The morphological appearance of distal tip cells is varied compared to control animals." ;
    oboInOwl:hasNarrowSynonym "distal tip cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000196" ;
    a owl:Class ;
    rdfs:label "distal tip cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006865
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000197
    obo:IAO_0000115 "Variations in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling)." ;
    oboInOwl:hasNarrowSynonym "cell induction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000197" ;
    a owl:Class ;
    rdfs:label "cell induction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000216 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0031129
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000198
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0001272 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000198" ;
    a owl:Class ;
    rdfs:label "obsolete vulval cell induction abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000199
    obo:IAO_0000115 "Any variation in the progression of the finger-like sensory sensilla that project from the tail and embed in the male fan from its formation to the mature structure when compared to control animals." ;
    oboInOwl:hasNarrowSynonym "male tail sensory ray development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000199" ;
    a owl:Class ;
    rdfs:label "male tail sensory ray development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001008 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006941
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000200
    obo:IAO_0000115 "Variations in the progression of structures/tissues surrounding a cell over time from its initial formation to its mature form compared to control." ;
    oboInOwl:hasNarrowSynonym "pericellular component development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000200" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "pericellular component development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000518 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:GO_0031012
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000201
    obo:IAO_0000115 "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time compared to control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "cuticle development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000201" ;
    a owl:Class ;
    rdfs:label "cuticle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000200 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042335
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000202
    obo:IAO_0000115 "Any variation in the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "alae abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000202" ;
    a owl:Class ;
    rdfs:label "alae variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000201 .

obo:WBPhenotype_0000203
    obo:IAO_0000115 "Animals exhibit variations in the characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner compared to control animals." ;
    oboInOwl:hasNarrowSynonym "odorant adaptation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000203" ;
    a owl:Class ;
    rdfs:label "odorant adaptation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001048 .

obo:WBPhenotype_0000204
    obo:IAO_0000115 "Variations in the anterior body muscle contraction (aBoc) step of the defecation cycle compared to control animals. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step." ;
    oboInOwl:hasBroadSynonym "aBoc" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "anterior body contraction abnormal", "anterior body contraction defective" ;
    oboInOwl:id "WBPhenotype:0000204" ;
    a owl:Class ;
    rdfs:label "anterior body contraction defecation cycle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001476 .

obo:WBPhenotype_0000205
    obo:IAO_0000115 "Any variation in the expulsion of gut contents compared to control. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion." ;
    oboInOwl:hasNarrowSynonym "expulsion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Exp" ;
    oboInOwl:id "WBPhenotype:0000205" ;
    a owl:Class ;
    rdfs:label "expulsion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000210 .

obo:WBPhenotype_0000206
    obo:IAO_0000115 "A non-sex chromosome fails to segregate away from its homologous chromosome, resulting in gametes with no or extra copies of the non-sex homolog." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000206" ;
    a owl:Class ;
    rdfs:label "autosomal nondisjunction meiosis" ;
    rdfs:subClassOf obo:WBPhenotype_0001174 .

obo:WBPhenotype_0000207
    obo:IAO_0000115 "Any variation in the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control ." ;
    oboInOwl:hasNarrowSynonym "defecation cycle abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Dec" ;
    oboInOwl:id "WBPhenotype:0000207" ;
    a owl:Class ;
    rdfs:label "defecation cycle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000650 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035882
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000208
    obo:IAO_0000115 "The mean time between the onset of the defecation motor program is greater than that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Dec-l", "reduced rate of defecation" ;
    oboInOwl:id "WBPhenotype:0000208" ;
    a owl:Class ;
    rdfs:label "long defecation cycle" ;
    rdfs:subClassOf obo:WBPhenotype_0000207 .

obo:WBPhenotype_0000209
    obo:IAO_0000115 "The mean time between the onset of the defecation motor program is shorter than that observed for control animals." ;
    oboInOwl:hasExactSynonym "posterior body wall shortened interval" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Dec-s", "fast Dec", "increased rate of defecation" ;
    oboInOwl:id "WBPhenotype:0000209" ;
    a owl:Class ;
    rdfs:label "short defecation cycle" ;
    rdfs:subClassOf obo:WBPhenotype_0000207 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030421
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000210
    obo:IAO_0000115 "Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp)." ;
    oboInOwl:hasNarrowSynonym "defecation contraction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000210" ;
    a owl:Class ;
    rdfs:label "defecation contraction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000650 .

obo:WBPhenotype_0000211
    obo:IAO_0000115 "The rhythmic contractions of the muscles coordinating the elimination of gut contents are no longer synchronized compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "defecation contraction mistimed" ;
    oboInOwl:id "WBPhenotype:0000211" ;
    a owl:Class ;
    rdfs:label "defecation contraction asynchronous" ;
    rdfs:subClassOf obo:WBPhenotype_0000210 .

obo:WBPhenotype_0000212
    obo:IAO_0000115 "Animals contain body regions that are more narrow or drawn together than adjacent body regions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000212" ;
    a owl:Class ;
    rdfs:label "body constriction" ;
    rdfs:subClassOf obo:WBPhenotype_0000072 .

obo:WBPhenotype_0000213
    obo:IAO_0000115 "Variations in the progression of a zygote from formation (gamete fusion) to just prior to the first cell division compared to control." ;
    oboInOwl:hasNarrowSynonym "zygotic development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000213" ;
    a owl:Class ;
    rdfs:label "zygotic development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0004422
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000214
    obo:IAO_0000115 "Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000214" ;
    a owl:Class ;
    rdfs:label "alpha amanitin hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_37415
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000215
    obo:IAO_0000115 "Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline." ;
    oboInOwl:hasExactSynonym "no germline" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000215" ;
    a owl:Class ;
    rdfs:label "no germ line" ;
    rdfs:subClassOf obo:WBPhenotype_0000812 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005784
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000216
    obo:IAO_0000115 "Any variation in the processes that govern acquisition of particular cell fates compared to control animals." ;
    oboInOwl:hasNarrowSynonym "cell fate specification abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000216" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell fate specification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0001708
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000217
    obo:IAO_0000115 "The time in which a muscle contraction event that controls feeding is increased compared to control. Contractions of the pharynx are necessary for bacterial uptake from the surrounding environment." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000217" ;
    a owl:Class ;
    rdfs:label "prolonged pharyngeal contraction" ;
    rdfs:subClassOf obo:WBPhenotype_0000980 .

obo:WBPhenotype_0000218
    obo:IAO_0000115 "An excess number of vulval precursor cells receive an inductive signal leading to an increased number of VPCs adopting vulval fates compared to control animals." ;
    oboInOwl:hasBroadSynonym "Hin" ;
    oboInOwl:hasNarrowSynonym "overinduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000218" ;
    a owl:Class ;
    rdfs:label "vulval cell induction increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001272 .

obo:WBPhenotype_0000219
    obo:IAO_0000115 "Vulval precursor cells receive a decrease in inductive signal leading to fewer VPCs adopting vulval fates compared to control animals." ;
    oboInOwl:hasNarrowSynonym "underinduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000219" ;
    a owl:Class ;
    rdfs:label "vulval cell induction reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001272 .

obo:WBPhenotype_0000220
    obo:IAO_0000115 "Any aberrancy in the processes that govern acquisition of vulval cell fates compared to control animals." ;
    oboInOwl:hasNarrowSynonym "vulva cell fate specification abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000220" ;
    a owl:Class ;
    rdfs:label "vulva cell fate specification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000216, obo:WBPhenotype_0000699 .

obo:WBPhenotype_0000221
    obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." ;
    oboInOwl:hasNarrowSynonym "neurotransmitter metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000221" ;
    a owl:Class ;
    rdfs:label "neurotransmitter metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042133
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000222
    obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter, compared to control." ;
    oboInOwl:hasNarrowSynonym "serotonin metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000222" ;
    a owl:Class ;
    rdfs:label "serotonin metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000221 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042428
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000223
    obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving acetylcholine, compared to control. Acetylcholine is the acetic acid ester of the organic base choline." ;
    oboInOwl:hasNarrowSynonym "acetylcholine metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000223" ;
    a owl:Class ;
    rdfs:label "acetylcholine metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000221 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008291
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000224
    obo:IAO_0000115 "Animals do not contain or are unable to maintain a perceivable level of serotonin capable of initiating or maintaining serotonin-dependent cell activity." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000224" ;
    a owl:Class ;
    rdfs:label "serotonin deficient" ;
    rdfs:subClassOf obo:WBPhenotype_0000222 .

obo:WBPhenotype_0000225
    obo:IAO_0000115 "Animals are unable to carry out the chemical reactions and pathways resulting in the formation of serotonin." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000225" ;
    a owl:Class ;
    rdfs:label "serotonin synthesis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000222 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042427
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000226
    obo:IAO_0000115 "Animals are unable to carry out any chemical reaction or pathway resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000226" ;
    a owl:Class ;
    rdfs:label "serotonin catabolism defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000222 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042429
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000227
    obo:IAO_0000115 "The inability of a male to properly turn during mating behavior. In C. elegans, males typically turn via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail." ;
    oboInOwl:hasNarrowSynonym "male turning abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000227" ;
    a owl:Class ;
    rdfs:label "male turning defective" ;
    rdfs:subClassOf obo:WBPhenotype_0004006 .

obo:WBPhenotype_0000228
    obo:IAO_0000115 "Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000228" ;
    a owl:Class ;
    rdfs:label "spontaneous mutation rate increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0000229
    obo:IAO_0000115 "Animals are shorter and thinner than control animals at the same developmental stage." ;
    oboInOwl:hasExactSynonym "body size reduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Sma" ;
    oboInOwl:id "WBPhenotype:0000229" ;
    a owl:Class ;
    rdfs:label "small" ;
    rdfs:subClassOf obo:WBPhenotype_0001726, obo:WBPhenotype_0001727 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000587
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000230
    obo:IAO_0000115 "The girth of the region posterior to the vulva is reduced compared to that anterior to the vulva (the Wit phenotype). In C. elegans this phenotype is associated with anteriorward misplacement of the CAN neurons." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Wit" ;
    oboInOwl:id "WBPhenotype:0000230" ;
    a owl:Class ;
    rdfs:label "tail withered" ;
    rdfs:subClassOf obo:WBPhenotype_0000073 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000585
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005741
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000231
    obo:IAO_0000115 "Animals exhibit variations in the physical dimensions of its body compared to control animals of the same developmental stage." ;
    oboInOwl:hasNarrowSynonym "body size abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000231" ;
    a owl:Class ;
    rdfs:comment "PATO:0000117." ;
    rdfs:label "body size variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000072 .

obo:WBPhenotype_0000232
    obo:IAO_0000115 "Variation in the migration pattern of CAN neurons. In C. elegans, CAN neurons move posteriorly from their birthplace in the head to positions near the middle of the embryo." ;
    oboInOwl:hasNarrowSynonym "CAN cell migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000232" ;
    a owl:Class ;
    rdfs:label "CAN cell migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001520 .

obo:WBPhenotype_0000233
    obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline, compared to control." ;
    oboInOwl:hasNarrowSynonym "dopamine metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000233" ;
    a owl:Class ;
    rdfs:label "dopamine metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000221, obo:WBPhenotype_0001518 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042417
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000234
    obo:IAO_0000115 "Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "dopamine levels decreased" ;
    oboInOwl:id "WBPhenotype:0000234" ;
    a owl:Class ;
    rdfs:label "dopamine deficient" ;
    rdfs:subClassOf obo:WBPhenotype_0000233 .

obo:WBPhenotype_0000235
    obo:IAO_0000115 "Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000235" ;
    a owl:Class ;
    rdfs:label "dopamine synthesis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000233 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042416
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000236
    obo:IAO_0000115 "Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000236" ;
    a owl:Class ;
    rdfs:label "dopamine catabolism defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000233 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042420
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000237
    obo:IAO_0000115 "Animals extend intensity of roaming and or dwelling activity compared to control animals. In C. elegans, hyperactivity may include an increase in nose-lifts per minute." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000237" ;
    a owl:Class ;
    rdfs:label "foraging hyperactive" ;
    rdfs:subClassOf obo:WBPhenotype_0000662 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060756
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000238
    obo:IAO_0000115 "Animals decrease intensity or rate of roaming and or dwelling activity compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000238" ;
    a owl:Class ;
    rdfs:label "foraging reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000662 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060756
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000239
    obo:IAO_0000115 "The descendants of a vulval precursor cell exhibit altered developmental programs compared to their counterparts in control animals. In C. elegans, the VPCs are P3.p-P8.p." ;
    oboInOwl:hasNarrowSynonym "vulval cell lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "VPC lineage abnormal" ;
    oboInOwl:id "WBPhenotype:0000239" ;
    a owl:Class ;
    rdfs:label "vulval cell lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000099 .

obo:WBPhenotype_0000240
    obo:IAO_0000115 "The processes governing the expansion of blast cell populations vary, such that cell populations are decreased compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000240" ;
    a owl:Class ;
    rdfs:label "blast cell proliferation reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000173 .

obo:WBPhenotype_0000241
    obo:IAO_0000115 "Animals exhibit an increase in the quantity of cells that have undergone programmed cell death but have not been engulfed." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000241" ;
    a owl:Class ;
    rdfs:label "accumulated cell corpses" ;
    rdfs:subClassOf obo:WBPhenotype_0000590 .

obo:WBPhenotype_0000242
    obo:IAO_0000115 "The epidermal cells of the embryo fail to elongate. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000242" ;
    a owl:Class ;
    rdfs:label "body elongation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001478 .

obo:WBPhenotype_0000243
    obo:IAO_0000115 "Removal of cell corpses through a dedicated engulfment pathway is defective." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "corpse engulfment defective", "persistent cell corpses" ;
    oboInOwl:id "WBPhenotype:0000243" ;
    a owl:Class ;
    rdfs:label "engulfment failure by killer cell" ;
    rdfs:subClassOf obo:WBPhenotype_0000885 .

obo:WBPhenotype_0000244
    obo:IAO_0000115 "Cells fail to complete the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "apoptosis block" ;
    oboInOwl:id "WBPhenotype:0000244" ;
    a owl:Class ;
    rdfs:label "apoptotic arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006915
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000245
    obo:IAO_0000115 "Variations in the movement of sex myoblasts compared to control animals. In C. elegans, the larval SM migrate anteriorly to the precise center of the developing hermaphrodite gonad." ;
    oboInOwl:hasNarrowSynonym "SM migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000245" ;
    a owl:Class ;
    rdfs:label "SM migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001230 .

obo:WBPhenotype_0000246
    obo:IAO_0000115 "Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000246" ;
    a owl:Class ;
    rdfs:label "defecation cycle variable length" ;
    rdfs:subClassOf obo:WBPhenotype_0000207 .

obo:WBPhenotype_0000247
    obo:IAO_0000115 "Failure to execute the characteristic response to sodium as defined by control animals. In C. elegans, sodium is typically an attractant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Na chemotaxis defective", "sodium acetate chemotaxis defective" ;
    oboInOwl:id "WBPhenotype:0000247" ;
    a owl:Class ;
    rdfs:label "sodium chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001440 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_26708
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000248
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000652 ;
    oboInOwl:hasNarrowSynonym "sensory neuroanatomy abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000248" ;
    a owl:Class ;
    rdfs:label "obsolete sensory neuroanatomy variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000249
    obo:IAO_0000115 "Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000249" ;
    a owl:Class ;
    rdfs:label "osmotic avoidance defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000663 .

obo:WBPhenotype_0000250
    obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol, compared to control." ;
    oboInOwl:hasNarrowSynonym "octopamine metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000250" ;
    a owl:Class ;
    rdfs:label "octopamine metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000221, obo:WBPhenotype_0001518 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0046333
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000251
    obo:IAO_0000115 "Animals do not contain or are unable to maintain a perceivable level of octopamine capable of initiating or maintaining dopamine-dependent cell activity." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000251" ;
    a owl:Class ;
    rdfs:label "octopamine deficient" ;
    rdfs:subClassOf obo:WBPhenotype_0000250 .

obo:WBPhenotype_0000252
    obo:IAO_0000115 "Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000252" ;
    a owl:Class ;
    rdfs:label "caffeine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_27732
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000253
    obo:IAO_0000115 "Animals exhibit a lack of consistency, regularity, or uniformity while traveling from one location to another." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "movement irregular" ;
    oboInOwl:id "WBPhenotype:0000253" ;
    a owl:Class ;
    rdfs:label "movement erratic" ;
    rdfs:subClassOf obo:WBPhenotype_0001701 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000330
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007626
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000254
    obo:IAO_0000115 "Failure to execute the characteristic response to chloride. In C. elegans, chloride is typically an attractant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Cl chemotaxis defective" ;
    oboInOwl:id "WBPhenotype:0000254" ;
    a owl:Class ;
    rdfs:label "chloride chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001439, obo:WBPhenotype_0001458 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_17996
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000255
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ;
    oboInOwl:hasNarrowSynonym "amphid phasmid morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000255" ;
    a owl:Class ;
    rdfs:comment "WBbt:0005394, WBbt:0006753." ;
    rdfs:label "amphid phasmid neuron morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001527 .

obo:WBPhenotype_0000256
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ;
    oboInOwl:hasNarrowSynonym "amphid morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000256" ;
    a owl:Class ;
    rdfs:comment "WBbt:0005394." ;
    rdfs:label "amphid neuron morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000255 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005391
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000257
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ;
    oboInOwl:hasNarrowSynonym "phasmid morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000257" ;
    a owl:Class ;
    rdfs:comment "WBbt:0006753." ;
    rdfs:label "phasmid neuron morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000255 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005425
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000258
    obo:IAO_0000115 "Variations in the regulated release of substances by a cell compared to control." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000723" ;
    oboInOwl:hasExactSynonym "cellular secretion abnormal" ;
    oboInOwl:hasNarrowSynonym "cell secretion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000258" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell secretion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0032940
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000259
    obo:IAO_0000115 "Variations in the regulated release of substances by nonneuronal cells that enclose or ensheath the tips of the sensory dendrites compared to control." ;
    oboInOwl:hasNarrowSynonym "sheath cell secretion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000259" ;
    a owl:Class ;
    rdfs:label "sheath cell secretion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000258 .

obo:WBPhenotype_0000260
    obo:IAO_0000115 "The regulated release of materials by sheath cells is disrupted." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000260" ;
    a owl:Class ;
    rdfs:label "sheath cell secretion failure" ;
    rdfs:subClassOf obo:WBPhenotype_0000259 .

obo:WBPhenotype_0000261
    obo:IAO_0000115 "Amphid sheath cells lack the ability to secrete vesicles and their contents within the amphid pocket." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000261" ;
    a owl:Class ;
    rdfs:label "amphid sheath secretion failure" ;
    rdfs:subClassOf obo:WBPhenotype_0000260 .

obo:WBPhenotype_0000262
    obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center." ;
    oboInOwl:hasNarrowSynonym "axoneme morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000262" ;
    a owl:Class ;
    rdfs:label "axoneme morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000615 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005930
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000263
    obo:IAO_0000115 "The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000263" ;
    a owl:Class ;
    rdfs:label "axoneme short" ;
    rdfs:subClassOf obo:WBPhenotype_0000262 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000574
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005930
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000264
    obo:IAO_0000115 "Failure to execute the characteristic response to cAMP as defined by control animals. In C. elegans, cAMP is typically an attractant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000264" ;
    a owl:Class ;
    rdfs:label "cAMP chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001463 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_17489
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000265
    obo:IAO_0000115 "Movement towards typically attractive volatile organic chemicals is altered as defined by control animals. In C. elegans, these odorants are typically sensed by the AWA and AWC neurons." ;
    oboInOwl:hasNarrowSynonym "odorant positive chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000265" ;
    a owl:Class ;
    rdfs:label "odorant positive chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000635, obo:WBPhenotype_0001048 .

obo:WBPhenotype_0000266
    obo:IAO_0000115 "Variations that disrupt stereotypical cleavage patterns (such as cleavage rate, division axes or asymmetric division) compared to control." ;
    oboInOwl:hasNarrowSynonym "cell cleavage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000266" ;
    a owl:Class ;
    rdfs:label "cell cleavage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 .

obo:WBPhenotype_0000267
    obo:IAO_0000115 "Any variation that causes a delay in the stereotypical cleavage event compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000267" ;
    a owl:Class ;
    rdfs:label "cell cleavage delayed" ;
    rdfs:subClassOf obo:WBPhenotype_0000266, obo:WBPhenotype_0000438 .

obo:WBPhenotype_0000268
    obo:IAO_0000115 "Any variation that causes a delay in the stereotypical cleavage pattern of the P cell compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000268" ;
    a owl:Class ;
    rdfs:label "P cell cleavage delayed" ;
    rdfs:subClassOf obo:WBPhenotype_0000267 .

obo:WBPhenotype_0000269
    obo:IAO_0000115 "OBSOLETE. Animals display a phenotype that has not yet been assigned to a current classification." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000269" ;
    a owl:Class ;
    rdfs:label "obsolete unclassified" ;
    owl:deprecated true .

obo:WBPhenotype_0000270
    obo:IAO_0000115 "Seemingly unrelated variations that concurrently occur during early embryonic development compared to control animals. In C. elegans, this can include multiple pronuclei, aberrant cytoplasmic texture, decrease in overall pace of development and osmotic sensitivity." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000270" ;
    a owl:Class ;
    rdfs:label "pleiotropic defects severe early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001007 .

obo:WBPhenotype_0000271
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0000318, obo:WBPhenotype_0001995 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000271" ;
    a owl:Class ;
    rdfs:label "obsolete cell cycle slow" ;
    owl:deprecated true .

obo:WBPhenotype_0000272
    obo:IAO_0000115 "The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate does not conform to the pattern observed in control animals (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000272" ;
    a owl:Class ;
    rdfs:label "egg laying irregular" ;
    rdfs:subClassOf obo:WBPhenotype_0000640 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000044
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000273
    obo:IAO_0000115 "The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000273" ;
    a owl:Class ;
    rdfs:label "thrashing reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001700 .

obo:WBPhenotype_0000274
    obo:IAO_0000115 "Animals lay eggs that are inviable." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000274" ;
    a owl:Class ;
    rdfs:label "dead eggs laid" ;
    rdfs:subClassOf obo:WBPhenotype_0000640, obo:WBPhenotype_0000806 .

obo:WBPhenotype_0000275
    obo:IAO_0000115 "Organisms respond to UV at a lower dose or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000275" ;
    a owl:Class ;
    rdfs:label "organism UV hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000143 .

obo:WBPhenotype_0000276
    obo:IAO_0000115 "Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism X ray response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000276" ;
    a owl:Class ;
    rdfs:label "organism X ray response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000686 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010165
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000277
    obo:IAO_0000115 "The timing of a biological cycle that recurs with regularity is delayed compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000277" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "rhythm slow" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048511
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000278
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency or translucency of a particular body region." ;
    oboInOwl:hasExactSynonym "body region pigmentation abnormal", "body region pigmentation variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000278" ;
    a owl:Class ;
    rdfs:label "body region pigmentation phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000521 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002247
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005738
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000279
    obo:IAO_0000115 "Males exhibit defects in the insertion of the male copulatory spicules into the mating partner. In C. elegan spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000279" ;
    a owl:Class ;
    rdfs:label "spicule insertion defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001414, obo:WBPhenotype_0004006 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0034609
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000280
    obo:IAO_0000115 "The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas)." ;
    oboInOwl:hasExactSynonym "gapped alae" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000280" ;
    a owl:Class ;
    rdfs:label "breaks in alae" ;
    rdfs:subClassOf obo:WBPhenotype_0001412 .

obo:WBPhenotype_0000281
    obo:IAO_0000115 "Variations in the progression of the muscles of the adult male reproductive system over time form their initial formation to their mature structure compared to control." ;
    oboInOwl:hasNarrowSynonym "male sex muscle development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000281" ;
    a owl:Class ;
    rdfs:label "male sex muscle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000669 .

obo:WBPhenotype_0000282
    obo:IAO_0000115 "Variations in the progression of the muscles of the adult hermaphrodite reproductive system over time form their initial formation to their mature structure compared to control." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite sex muscle development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000282" ;
    a owl:Class ;
    rdfs:label "hermaphrodite sex muscle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000669 .

obo:WBPhenotype_0000283
    obo:IAO_0000115 "Animals exhibit defects in the continuity of lumen between the vulva and uterus compared to control animals." ;
    oboInOwl:hasNarrowSynonym "AC block" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000283" ;
    a owl:Class ;
    rdfs:label "vulva uterus connection defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000624 .

obo:WBPhenotype_0000284
    obo:IAO_0000115 "Any defect in the process whereby a male inseminates his partner by introducing sperm into the genital tract." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000284" ;
    a owl:Class ;
    rdfs:label "sperm transfer defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001414, obo:WBPhenotype_0004006 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007320
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000285
    obo:IAO_0000115 "The extreme ends of any of the finger-like sensory sensilla that project from the tail and embed in the male fan appear bloated or distended." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000285" ;
    a owl:Class ;
    rdfs:label "ray tips swollen" ;
    rdfs:subClassOf obo:WBPhenotype_0000505 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001851
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006941
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000286
    obo:IAO_0000115 "Embryos fail to be organized in the same manner as observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000286" ;
    a owl:Class ;
    rdfs:label "embryo disorganized" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000937
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000003
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000287
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000510 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000287" ;
    a owl:Class ;
    rdfs:label "obsolete vulval invagination L4 abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000288
    obo:IAO_0000115 "Variations in the progression of the lineages that gives rise to all germ cells, lying in the region adjacent to the proximal gonad (on the side furthest from the founder cells of the somatic gonad), over time compared to control animals." ;
    oboInOwl:hasNarrowSynonym "distal germline abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "distal germ line abnormal" ;
    oboInOwl:id "WBPhenotype:0000288" ;
    a owl:Class ;
    rdfs:label "distal germline variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000812 .

obo:WBPhenotype_0000289
    obo:IAO_0000115 "Any variation in the form, structure or composition of the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "uterus morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000289" ;
    a owl:Class ;
    rdfs:label "uterus morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001335 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006760
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000290
    obo:IAO_0000115 "Animals lack fully specialized male gametes that are competent for fertilization." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "no sperm" ;
    oboInOwl:id "WBPhenotype:0000290" ;
    a owl:Class ;
    rdfs:label "sperm absent" ;
    rdfs:subClassOf obo:WBPhenotype_0000395 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006798
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000291
    obo:IAO_0000115 "Hermaphrodites lack fully specialized female gametes that are competent for fertilization." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "oocytes absent" ;
    oboInOwl:id "WBPhenotype:0000291" ;
    a owl:Class ;
    rdfs:label "no oocytes" ;
    rdfs:subClassOf obo:WBPhenotype_0000395 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006797
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000292
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a organ system." ;
    oboInOwl:hasExactSynonym "organ system pigmentation abnormal", "organ system pigmentation variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000292" ;
    a owl:Class ;
    rdfs:label "organ system pigmentation phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000521 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002247
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005746
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000293
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the alimentary system." ;
    oboInOwl:hasNarrowSynonym "alimentary system pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000293" ;
    a owl:Class ;
    rdfs:label "alimentary system pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000292 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002247
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005748
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000294
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that decrease the transparency/translucency of the intestine." ;
    oboInOwl:hasBroadSynonym "Din" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000294" ;
    a owl:Class ;
    rdfs:label "intestine dark" ;
    rdfs:subClassOf obo:WBPhenotype_0000293 .

obo:WBPhenotype_0000295
    obo:IAO_0000115 "Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals." ;
    oboInOwl:hasNarrowSynonym "intrinsic thermotolerance increased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000295" ;
    a owl:Class ;
    rdfs:label "thermotolerance increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000146 .

obo:WBPhenotype_0000296
    obo:IAO_0000115 "The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) are deformed. In C. elegans males there are two copulatory spicules." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000296" ;
    a owl:Class ;
    rdfs:label "spicules crumpled" ;
    rdfs:subClassOf obo:WBPhenotype_0000443 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001810
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005312
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000297
    obo:IAO_0000115 "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001241" ;
    oboInOwl:hasExactSynonym "ray fusion" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000297" ;
    a owl:Class ;
    rdfs:label "rays fused" ;
    rdfs:subClassOf obo:WBPhenotype_0000165, obo:WBPhenotype_0000199, obo:WBPhenotype_0000505 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000642
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:WBbt_0006941
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006941
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000298
    obo:IAO_0000115 "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are shifted from their customary place." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000298" ;
    a owl:Class ;
    rdfs:label "rays displaced" ;
    rdfs:subClassOf obo:WBPhenotype_0000505 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001852
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006941
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000299
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "sensillum morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "chemosensory cell morphology abnormal" ;
    oboInOwl:id "WBPhenotype:0000299" ;
    a owl:Class ;
    rdfs:label "sensillum morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000604 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006929
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000300
    obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in control animals. Sheath cells in C.elegans have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures." ;
    oboInOwl:hasNarrowSynonym "amphid sheath cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000300" ;
    a owl:Class ;
    rdfs:label "amphid sheath cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001527 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006754
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000301
    obo:IAO_0000115 "A migrating distal tip cell (DTC) fails to follow the stereotypical path. In C. elegans this path is U-shaped and results in the formation of reflexed gonadal arm." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000301" ;
    a owl:Class ;
    rdfs:label "distal tip cell reflex failure" ;
    rdfs:subClassOf obo:WBPhenotype_0000195 .

obo:WBPhenotype_0000302
    obo:IAO_0000115 "Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000302" ;
    a owl:Class ;
    rdfs:label "benzaldehyde chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001060, obo:WBPhenotype_0001468 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_22698
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000303
    obo:IAO_0000115 "Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000303" ;
    a owl:Class ;
    rdfs:label "diacetyl chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001470 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_16583
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000304
    obo:IAO_0000115 "Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000304" ;
    a owl:Class ;
    rdfs:label "isoamyl alcohol chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001472 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_15837
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000305
    obo:IAO_0000115 "Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that influences behavior in control animals." ;
    oboInOwl:hasNarrowSynonym "pheromone sensation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000305" ;
    a owl:Class ;
    rdfs:label "pheromone sensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 .

obo:WBPhenotype_0000306
    obo:IAO_0000115 "Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals." ;
    oboInOwl:hasNarrowSynonym "transgene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000306" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "transgene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0000307
    obo:IAO_0000115 "Animals fail to detect a pheromone stimulus that induces dauer formation in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000307" ;
    a owl:Class ;
    rdfs:label "dauer pheromone sensation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001479 .

obo:WBPhenotype_0000308
    obo:IAO_0000115 "Any variation in the processes that govern development of the dauer larva, a developmentally arrested, larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions. In C. elegans this is an alternative third larval stage." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000159" ;
    oboInOwl:hasExactSynonym "dauer development abnormal", "dauer development variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "dauer arrest abnormal", "dauer arrest variant", "diapause variant" ;
    oboInOwl:id "WBPhenotype:0000308" ;
    a owl:Class ;
    rdfs:label "dauer development phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000750, obo:WBPhenotype_0002527 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040024
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000309
    obo:IAO_0000115 "Any variation that decreases the ability of dauer larva to tolerate the exposure to sodium dodecyl sulfate (a detergent) compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000309" ;
    a owl:Class ;
    rdfs:label "SDS sensitive dauer" ;
    rdfs:subClassOf obo:WBPhenotype_0001546, obo:WBPhenotype_0001918 .

obo:WBPhenotype_0000310
    obo:IAO_0000115 "Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000310" ;
    a owl:Class ;
    rdfs:label "cilia absent" ;
    rdfs:subClassOf obo:WBPhenotype_0000615 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005929
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000311
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000688 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000311" ;
    a owl:Class ;
    rdfs:label "obsolete semi sterile" ;
    owl:deprecated true .

obo:WBPhenotype_0000312
    obo:IAO_0000115 "Animals are incapable of synthesizing pheromones that induce dauer formation in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000312" ;
    a owl:Class ;
    rdfs:label "dauer pheromone production defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000191, obo:WBPhenotype_0001547 .

obo:WBPhenotype_0000313
    obo:IAO_0000115 "Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis)." ;
    oboInOwl:hasNarrowSynonym "meiotic progression during oogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000313" ;
    a owl:Class ;
    rdfs:label "meiotic progression during oogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000186 .

obo:WBPhenotype_0000314
    obo:IAO_0000115 "Animals are slight or meager in body size compared to control animals at the same developmental stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000314" ;
    a owl:Class ;
    rdfs:label "scrawny" ;
    rdfs:subClassOf obo:WBPhenotype_0000231 .

obo:WBPhenotype_0000315
    obo:IAO_0000115 "Any variation with respect to perception or response to mechanical stimuli compared to control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000513" ;
    oboInOwl:hasBroadSynonym "Mec" ;
    oboInOwl:hasExactSynonym "touch response abnormal" ;
    oboInOwl:hasNarrowSynonym "mechanosensation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000315" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "mechanosensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525, obo:WBPhenotype_0000738 .

obo:WBPhenotype_0000316
    obo:IAO_0000115 "Failure to execute a characteristic response when struck or stroked in the posterior region. In C. elegans, animals move forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail." ;
    oboInOwl:hasBroadSynonym "touch resistant posterior body" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "touch insensitive tail" ;
    oboInOwl:id "WBPhenotype:0000316" ;
    a owl:Class ;
    rdfs:label "touch resistant tail" ;
    rdfs:subClassOf obo:WBPhenotype_0000456 .

obo:WBPhenotype_0000317
    obo:IAO_0000115 "Animals are deficient in the foraging response in which an animal quickly pulls its head away from a stimulus to the nose (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000317" ;
    a owl:Class ;
    rdfs:label "head withdrawal defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0000318
    obo:IAO_0000115 "Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000318" ;
    a owl:Class ;
    rdfs:label "cell cycle delayed" ;
    rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0001995 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000502
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007049
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000319
    obo:IAO_0000115 "Animals have increased girth and increased length compared to control animals at the same developmental stage." ;
    oboInOwl:hasExactSynonym "body size enlarged" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000319" ;
    a owl:Class ;
    rdfs:label "large" ;
    rdfs:subClassOf obo:WBPhenotype_0000231 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000586
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000320
    obo:IAO_0000115 "Animals show a decrease in survivorship after thawing compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000320" ;
    a owl:Class ;
    rdfs:label "reduced viability after freezing" ;
    rdfs:subClassOf obo:WBPhenotype_0000141 .

obo:WBPhenotype_0000321
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control." ;
    oboInOwl:hasNarrowSynonym "nose morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000321" ;
    a owl:Class ;
    rdfs:label "nose morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000071 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0008426
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000322
    obo:IAO_0000115 "The extreme anterior part of the body appears blunted in shape." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000322" ;
    a owl:Class ;
    rdfs:label "nose rounded" ;
    rdfs:subClassOf obo:WBPhenotype_0000321 .

obo:WBPhenotype_0000323
    obo:IAO_0000115 "The most anterior portion of the animal appears bloated or distended." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000323" ;
    a owl:Class ;
    rdfs:label "head swollen" ;
    rdfs:subClassOf obo:WBPhenotype_0000071 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001851
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005739
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000324
    obo:IAO_0000115 "Animals exhibit a decreased body length compared to control animals of the same developmental stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000324" ;
    a owl:Class ;
    rdfs:label "short" ;
    rdfs:subClassOf obo:WBPhenotype_0001726 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000574
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000325
    obo:IAO_0000115 "Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000325" ;
    a owl:Class ;
    rdfs:label "arecoline hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001579 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_2814
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000326
    obo:IAO_0000115 "Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000326" ;
    a owl:Class ;
    rdfs:label "arecoline resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001578 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_2814
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000327
    obo:IAO_0000115 "Any defect in the muscle contractions of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000327" ;
    a owl:Class ;
    rdfs:label "corpus contraction defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000747 .

obo:WBPhenotype_0000328
    obo:IAO_0000115 "Variations in the rhythmic contractions of the posterior pharynx (terminal bulb), such as timing, strength etc. In C. elegans contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine." ;
    oboInOwl:hasNarrowSynonym "terminal bulb contraction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000328" ;
    a owl:Class ;
    rdfs:label "terminal bulb contraction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000980 .

obo:WBPhenotype_0000329
    obo:IAO_0000115 "The rhythmic contractions of pharyngeal compartments are no longer synchronized compared to control. In C. elegans the corpus and terminal bulb normally contract simultaneously." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000329" ;
    a owl:Class ;
    rdfs:label "pumping asynchronous" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 .

obo:WBPhenotype_0000330
    obo:IAO_0000115 "Defects in rhythmic pharyngeal relaxations compared to control animals. In C. elegans pharyngeal relaxation follows a contraction event and facilitates bacterial trapping within the pharynx while expelling liquid." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000330" ;
    a owl:Class ;
    rdfs:label "pharyngeal relaxation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001004 .

obo:WBPhenotype_0000331
    obo:IAO_0000115 "Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasNarrowSynonym "ouabain resistant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000331" ;
    a owl:Class ;
    rdfs:label "inhibitors of na k atpase resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 .

obo:WBPhenotype_0000332
    obo:IAO_0000115 "Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000332" ;
    a owl:Class ;
    rdfs:label "inhibitors of sodium potassium ATPase hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_63510
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000333
    obo:IAO_0000115 "The time interval of the stereotyped sequence of muscle contractions by individual pharyngeal muscles that act to draw food into the pharynx is shorter compared to that observed in control (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000333" ;
    a owl:Class ;
    rdfs:label "pharyngeal pumps brief" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 .

obo:WBPhenotype_0000334
    obo:IAO_0000115 "Failure of muscle contractions in the corpus and isthmus to trap and transport bacteria posteriorly in the pharynx." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000334" ;
    a owl:Class ;
    rdfs:label "isthmus corpus slippery" ;
    rdfs:subClassOf obo:WBPhenotype_0000335 .

obo:WBPhenotype_0000335
    obo:IAO_0000115 "Failure of pharyngeal contractions to trap and transport bacteria posteriorly. In C. elegans this defect results in a distention of the pharyngeal lumen." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000335" ;
    a owl:Class ;
    rdfs:label "pharynx slippery" ;
    rdfs:subClassOf obo:WBPhenotype_0000634 .

obo:WBPhenotype_0000336
    obo:IAO_0000115 "Variations in the rhythmic relaxations of the posterior pharynx (terminal bulb). In C. elegans the relaxation of the terminal bulb returns the grinder to its relaxed forward position." ;
    oboInOwl:hasNarrowSynonym "terminal bulb relaxation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000336" ;
    a owl:Class ;
    rdfs:label "terminal bulb relaxation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000330 .

obo:WBPhenotype_0000337
    obo:IAO_0000115 "Failure of the grinder to come to a full relaxed position between pumps compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000337" ;
    a owl:Class ;
    rdfs:label "grinder relaxation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001480 .

obo:WBPhenotype_0000338
    obo:IAO_0000115 "Swelling in the post anal region compared to control. In C. elegans this swelling can be associated with infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum." ;
    oboInOwl:hasBroadSynonym "Dar" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "deformed anal region" ;
    oboInOwl:id "WBPhenotype:0000338" ;
    a owl:Class ;
    rdfs:label "tail swelling" ;
    rdfs:subClassOf obo:WBPhenotype_0000073 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001851
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005741
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000339
    obo:IAO_0000115 "Worms sporatically appear turgid or swollen as a result of an excess number of eggs being retained in the uterus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000339" ;
    a owl:Class ;
    rdfs:label "transient bloating" ;
    rdfs:subClassOf obo:WBPhenotype_0000862 .

obo:WBPhenotype_0000340
    obo:IAO_0000115 "Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000340" ;
    a owl:Class ;
    rdfs:label "imipramine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001598 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_47499
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000341
    obo:IAO_0000115 "Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000341" ;
    a owl:Class ;
    rdfs:label "imipramine hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_47499
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000342
    obo:IAO_0000115 "Any variation in the form, structure or composition of the adult male tail including the lateral fan and rays compared to control." ;
    oboInOwl:hasNarrowSynonym "bursa morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000342" ;
    a owl:Class ;
    rdfs:label "bursa morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000070 .

obo:WBPhenotype_0000343
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000908 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000343" ;
    a owl:Class ;
    rdfs:label "obsolete cloaca morphology abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000344
    obo:IAO_0000115 "Any of the contents that comprise the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus extend into the external environment through the cloacal opening." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000344" ;
    a owl:Class ;
    rdfs:label "cloacal structures protrude" ;
    rdfs:subClassOf obo:WBPhenotype_0000908 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001598
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005774
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000345
    obo:IAO_0000115 "Any variation that alters the physical partitioning and separation of a vulval precursor cell into daughter cells compared to control." ;
    oboInOwl:hasNarrowSynonym "VPC cell division abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000345" ;
    a owl:Class ;
    rdfs:label "VPC cell division variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 .

obo:WBPhenotype_0000346
    obo:IAO_0000115 "Adult animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals." ;
    oboInOwl:hasNarrowSynonym "adult pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000346" ;
    a owl:Class ;
    rdfs:label "adult pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001009 .

obo:WBPhenotype_0000347
    obo:IAO_0000115 "Any variation in the progression of the cuticle-lined sinus opening on the posterior ventral surface of the animal over time from its formation to its mature structure compared to control (Wormatlas). The function of the rectum is to excrete waste products from the alimentary system." ;
    oboInOwl:hasNarrowSynonym "rectal development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000347" ;
    a owl:Class ;
    rdfs:label "rectal development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000617 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005773
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000348
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0001735 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000348" ;
    a owl:Class ;
    rdfs:label "obsolete muscle activation defective" ;
    owl:deprecated true .

obo:WBPhenotype_0000349
    obo:IAO_0000115 "A semi-paralysed body phenotype in which muscle tone is lost and the animal fails to actively control its body shape (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "floppy", "limp" ;
    oboInOwl:id "WBPhenotype:0000349" ;
    a owl:Class ;
    rdfs:label "flaccid" ;
    rdfs:subClassOf obo:WBPhenotype_0000001 .

obo:WBPhenotype_0000350
    obo:IAO_0000115 "Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the hermaphrodite tail compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000350" ;
    a owl:Class ;
    rdfs:label "hermaphrodite tail spike variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000968 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001340
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006979
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000351
    obo:IAO_0000115 "Animals fail to emerge from an egg shell." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000351" ;
    a owl:Class ;
    rdfs:label "failure to hatch" ;
    rdfs:subClassOf obo:WBPhenotype_0000048, obo:WBPhenotype_0000050 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035188
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000352
    obo:IAO_0000115 "Backward movement is not coordinated as in control. This often causes jerky or spastic backward locomotion." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000352" ;
    a owl:Class ;
    rdfs:label "backing uncoordinated" ;
    rdfs:subClassOf obo:WBPhenotype_0001005 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000770
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043057
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000353
    obo:IAO_0000115 "Animals spend more time backing compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000353" ;
    a owl:Class ;
    rdfs:label "backing increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001005 .

obo:WBPhenotype_0000354
    obo:IAO_0000115 "Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues." ;
    oboInOwl:hasNarrowSynonym "cell differentiation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000354" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell differentiation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030154
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000355
    obo:IAO_0000115 "Specialization of HSN precursor cells to mature HSN neurons occurs at an earlier stage of development compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000355" ;
    a owl:Class ;
    rdfs:label "HSN differentiation precocious" ;
    rdfs:subClassOf obo:WBPhenotype_0000354, obo:WBPhenotype_0000439 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000694
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030154
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0006830
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000356
    obo:IAO_0000115 "The progression of immature germ cells to functional sperm is retarded compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000356" ;
    a owl:Class ;
    rdfs:label "spermatogenesis delayed" ;
    rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0000670 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000502
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007283
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000357
    obo:IAO_0000115 "Animals lay inactivated oocytes. In C elegans this may be due to perturbations that eliminate spermatogenesis or result in the production of defective sperm." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000357" ;
    a owl:Class ;
    rdfs:label "unfertilized oocytes laid" ;
    rdfs:subClassOf obo:WBPhenotype_0000640 .

obo:WBPhenotype_0000358
    obo:IAO_0000115 "Animals execute supernumerary cell divisions post-hatching." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "supernumerary cell divisions" ;
    oboInOwl:id "WBPhenotype:0000358" ;
    a owl:Class ;
    rdfs:label "extra cell division postembryonic" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000359
    obo:IAO_0000115 "Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response." ;
    oboInOwl:hasNarrowSynonym "tunicamycin response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000359" ;
    a owl:Class ;
    rdfs:label "tunicamycin response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1904576
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000360
    obo:IAO_0000115 "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is impaired." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000360" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "cytoplasmic streaming defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002612 .

obo:WBPhenotype_0000361
    obo:IAO_0000115 "Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas)." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "arrest during epiboly" ;
    oboInOwl:id "WBPhenotype:0000361" ;
    a owl:Class ;
    rdfs:label "lima bean arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000867 .

obo:WBPhenotype_0000362
    obo:IAO_0000115 "Any variation in the progression of the fluid-filled compartment inside the developing embryo at the onset of gastrulation over time from its formation to its mature structure compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "blastocoel abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000362" ;
    a owl:Class ;
    rdfs:label "blastocoel variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000047 .

obo:WBPhenotype_0000363
    obo:IAO_0000115 "Any variation that delays the physical partitioning and separation of a cell into daughter cells compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000363" ;
    a owl:Class ;
    rdfs:label "cell division slow" ;
    rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0000746 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051301
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000364
    obo:IAO_0000115 "The birefringent inclusions typically found in the intestinal cytoplasm accumulate extracellularly in the intestinal lumen." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000364" ;
    a owl:Class ;
    rdfs:label "gut granule birefringence misplaced" ;
    rdfs:subClassOf obo:WBPhenotype_0002240 .

obo:WBPhenotype_0000365
    obo:IAO_0000115 "Variations in the ability of an embryo to maintain osmotic balance. In C.elegans this can result in an embryo filling the egg shell and lysing." ;
    oboInOwl:hasBroadSynonym "Emb", "Eos" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000365" ;
    a owl:Class ;
    rdfs:label "embryo osmotic integrity defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001178 .

obo:WBPhenotype_0000366
    obo:IAO_0000115 "Cessation of development that normally occurs in C. elegans 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "active elongation arrest" ;
    oboInOwl:id "WBPhenotype:0000366" ;
    a owl:Class ;
    rdfs:label "three fold arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000779 .

obo:WBPhenotype_0000367
    obo:IAO_0000115 "Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas)." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "end of epiboly arrest" ;
    oboInOwl:id "WBPhenotype:0000367" ;
    a owl:Class ;
    rdfs:label "comma arrest emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000864 .

obo:WBPhenotype_0000368
    obo:IAO_0000115 "Cessation of development that normally occurs in C. elegans 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "arrest beginning elongation" ;
    oboInOwl:id "WBPhenotype:0000368" ;
    a owl:Class ;
    rdfs:label "one point five fold arrest emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000864 .

obo:WBPhenotype_0000369
    obo:IAO_0000115 "Cessation of development during the final two stages in embryogenesis, 'early pretzel' stage and 'late pretzel' stage, just prior to hatching. The animal now is folded into four lengths within the eggshell and resembles a pretzel. By early pretzel stage, the head begins to move independently from the body (Wormatlas)." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "end of elongation arrest" ;
    oboInOwl:id "WBPhenotype:0000369" ;
    a owl:Class ;
    rdfs:label "pretzel arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000779 .

obo:WBPhenotype_0000370
    obo:IAO_0000115 "The fertilized oocytes have a greater than standard length measured end to end compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000370" ;
    a owl:Class ;
    rdfs:label "egg long" ;
    rdfs:subClassOf obo:WBPhenotype_0000373 .

obo:WBPhenotype_0000371
    obo:IAO_0000115 "The physical partitioning and separation of a cell into daughter cells is interupted." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000371" ;
    a owl:Class ;
    rdfs:label "cell division incomplete" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051301
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000372
    obo:IAO_0000115 "Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000372" ;
    a owl:Class ;
    rdfs:label "no polar body formation" ;
    rdfs:subClassOf obo:WBPhenotype_0000775 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0008429
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000373
    obo:IAO_0000115 "The overall structure or appearance of fertilized oocytes that are laid exhibit nonconsistent and significant deviation from that of control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000373" ;
    a owl:Class ;
    rdfs:label "egg shape variable" ;
    rdfs:subClassOf obo:WBPhenotype_0000037 .

obo:WBPhenotype_0000374
    obo:IAO_0000115 "The time interval in which early embryonic cell divisions occur is increased compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000374" ;
    a owl:Class ;
    rdfs:label "early divisions prolonged" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 .

obo:WBPhenotype_0000375
    obo:IAO_0000115 "The time interval in which late embryonic cell divisions occur is increased compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000375" ;
    a owl:Class ;
    rdfs:label "later divisions prolonged" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 .

obo:WBPhenotype_0000376
    obo:IAO_0000115 "Animals lack the inner space of the uterus through which the fertilized egg passes on its way out of the nematode via the vulva (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000376" ;
    a owl:Class ;
    rdfs:label "no uterine cavity" ;
    rdfs:subClassOf obo:WBPhenotype_0000289 .

obo:WBPhenotype_0000377
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the internal space of the excretory canal compared to control animals." ;
    oboInOwl:hasNarrowSynonym "canal lumen morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000377" ;
    a owl:Class ;
    rdfs:label "canal lumen morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000704 .

obo:WBPhenotype_0000378
    obo:IAO_0000115 "Pharyngeal muscle contractions show less displacement than that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000378" ;
    a owl:Class ;
    rdfs:label "pharyngeal pumping shallow" ;
    rdfs:subClassOf obo:WBPhenotype_0000634 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001472
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043050
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000379
    obo:IAO_0000115 "The most anterior portion of the animal contains a V-shaped indentation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000379" ;
    a owl:Class ;
    rdfs:label "head notched" ;
    rdfs:subClassOf obo:WBPhenotype_0000071 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001495
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005739
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000380
    obo:IAO_0000115 "The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step in C. elegans specialized enteric muscles contract to expel the contents of the gut through the anus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000380" ;
    a owl:Class ;
    rdfs:label "expulsion infrequent" ;
    rdfs:subClassOf obo:WBPhenotype_0000996 .

obo:WBPhenotype_0000381
    obo:IAO_0000115 "Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000381" ;
    a owl:Class ;
    rdfs:label "serotonin reuptake inhibitor resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_50949
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000382
    obo:IAO_0000115 "Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000382" ;
    a owl:Class ;
    rdfs:label "serotonin reuptake inhibitor hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_50949
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000383
    obo:IAO_0000115 "The de novo synthesis of any lipid species is reduced compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid synthesis decreased" ;
    oboInOwl:id "WBPhenotype:0000383" ;
    a owl:Class ;
    rdfs:label "lipid synthesis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000725 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008610
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000384
    obo:IAO_0000115 "Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues)." ;
    oboInOwl:hasNarrowSynonym "axon guidance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "axon pathfinding abnormal" ;
    oboInOwl:id "WBPhenotype:0000384" ;
    a owl:Class ;
    rdfs:label "axon guidance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001224 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007411
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000385
    obo:IAO_0000115 "Animals produce an increased sperm population compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000385" ;
    a owl:Class ;
    rdfs:label "sperm excess" ;
    rdfs:subClassOf obo:WBPhenotype_0000670 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006798
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000386
    obo:IAO_0000115 "Programmed cell death of germ cells caused by exposure to DNA-damaging chemical agents does not occur to the same extent as it does in control animals." ;
    oboInOwl:hasNarrowSynonym "genotoxic induced apoptosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "DNA damage induced apoptosis abnormal" ;
    oboInOwl:id "WBPhenotype:0000386" ;
    a owl:Class ;
    rdfs:label "genotoxic chemical induced apoptosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002152 .

obo:WBPhenotype_0000387
    obo:IAO_0000115 "The mature male gametes lack self-propelled movement." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000387" ;
    a owl:Class ;
    rdfs:label "sperm nonmotile" ;
    rdfs:subClassOf obo:WBPhenotype_0000987 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000300
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006798
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000388
    obo:IAO_0000115 "Any variation in the form, structure or composition of the mature male gamete, which merges with an oocyte to create a fertilized embryo copared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "sperm morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000388" ;
    a owl:Class ;
    rdfs:label "sperm morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000900 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006798
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000389
    obo:IAO_0000115 "Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte." ;
    oboInOwl:hasBroadSynonym "Fer", "Spe" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000389" ;
    a owl:Class ;
    rdfs:label "hermaphrodite sperm fertilization defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000694, obo:WBPhenotype_0002440 .

obo:WBPhenotype_0000390
    obo:IAO_0000115 "Spermatids fail to mature into active sperm. In C. elegans round sessile spermatids mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "spermiogenesis defective" ;
    oboInOwl:id "WBPhenotype:0000390" ;
    a owl:Class ;
    rdfs:label "spermatid activation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000670 .

obo:WBPhenotype_0000391
    obo:IAO_0000115 "Animals lack one or more of the stereotyped muscle contractions that result in defecation compared to control. In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000391" ;
    a owl:Class ;
    rdfs:label "defecation missing motor steps" ;
    rdfs:subClassOf obo:WBPhenotype_0000650 .

obo:WBPhenotype_0000392
    obo:IAO_0000115 "Animals exhibit an increase in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000392" ;
    a owl:Class ;
    rdfs:label "intestinal fluorescence increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000293 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001926
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005772
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000393
    obo:IAO_0000115 "Characteristic movement of cells from one site to another is abolished compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000393" ;
    a owl:Class ;
    rdfs:label "cell migration failure" ;
    rdfs:subClassOf obo:WBPhenotype_0000594 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016477
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000394
    obo:IAO_0000115 "Any variation in the movement of a protein through a gel matrix when an electric field is applied compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000394" ;
    a owl:Class ;
    rdfs:label "electrophoretic variant protein" ;
    rdfs:subClassOf obo:WBPhenotype_0000112 .

obo:WBPhenotype_0000395
    obo:IAO_0000115 "Animals are agametic (lack mature germ cells)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000395" ;
    a owl:Class ;
    rdfs:label "no differentiated gametes" ;
    rdfs:subClassOf obo:WBPhenotype_0000894 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CL_0000300
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000396
    obo:IAO_0000115 "Gonadal arms do not bend or curve. In C. elegans gonad arms normally reflex to form a stereotypical U-shaped pattern." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000396" ;
    a owl:Class ;
    rdfs:label "non reflexed gonad arms" ;
    rdfs:subClassOf obo:WBPhenotype_0000399 .

obo:WBPhenotype_0000397
    obo:IAO_0000115 "Animals do not respond to prodding with a fine platinum wire or similar tool compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "harsh body touch insensitive" ;
    oboInOwl:id "WBPhenotype:0000397" ;
    a owl:Class ;
    rdfs:label "harsh body touch resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000456 .

obo:WBPhenotype_0000398
    obo:IAO_0000115 "Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "light body touch insensitive" ;
    oboInOwl:id "WBPhenotype:0000398" ;
    a owl:Class ;
    rdfs:label "light body touch resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000456 .

obo:WBPhenotype_0000399
    obo:IAO_0000115 "Any variation in the progression of the components of the gonad that are separate from the germline proper over time from its formation to its mature structure compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "somatic gonad development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000399" ;
    a owl:Class ;
    rdfs:label "somatic gonad development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000691 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005785
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000400
    obo:IAO_0000115 "The developmental progression of the set of precursor cells that later give rise to the somatic tissues of the gonadal tract is impaired (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000400" ;
    a owl:Class ;
    rdfs:label "somatic gonad primordium development defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000399 .

obo:WBPhenotype_0000401
    obo:IAO_0000115 "Animals lack the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000401" ;
    a owl:Class ;
    rdfs:label "no uterus" ;
    rdfs:subClassOf obo:WBPhenotype_0000624 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006760
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000402
    obo:IAO_0000115 "Lawn avoidance refers to behavior in which animals initially enter the bacterial lawn but later exit and remain near the edge of the bacteria. Lawn avoidance is often a response to bacterial food, that is pathogenic or low quality to the animal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000402" ;
    a owl:Class ;
    rdfs:label "avoids bacterial lawn" ;
    rdfs:subClassOf obo:WBPhenotype_0000659, obo:WBPhenotype_0002545 .

obo:WBPhenotype_0000403
    obo:IAO_0000115 "Any defect in the movement of sperm out of the seminal vesicle and into the vas deferens following tonic insertion of spicules into the mating partner compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000403" ;
    a owl:Class ;
    rdfs:label "sperm transfer initiation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000284 .

obo:WBPhenotype_0000404
    obo:IAO_0000115 "The emergence of larvae from their protective egg shells is retarded compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000404" ;
    a owl:Class ;
    rdfs:label "delayed hatching" ;
    rdfs:subClassOf obo:WBPhenotype_0000048, obo:WBPhenotype_0000438 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000502
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035188
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000405
    obo:IAO_0000115 "The size of haploid female germ cells (oocytes) are significantly larger compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "oocytes large" ;
    oboInOwl:id "WBPhenotype:0000405" ;
    a owl:Class ;
    rdfs:label "giant oocytes" ;
    rdfs:subClassOf obo:WBPhenotype_0001260 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000586
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006797
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000406
    obo:IAO_0000115 "Animals have protrusions or bumps on their exterior which are not characteristic of control animals." ;
    oboInOwl:hasBroadSynonym "Lpy" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000406" ;
    a owl:Class ;
    rdfs:label "lumpy" ;
    rdfs:subClassOf obo:WBPhenotype_0000535 .

obo:WBPhenotype_0000407
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0001509 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000407" ;
    a owl:Class ;
    rdfs:label "obsolete ray loss" ;
    owl:deprecated true .

obo:WBPhenotype_0000408
    obo:IAO_0000115 "The process through which a dauer larva reverts to normal developmental programs is blocked." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000408" ;
    a owl:Class ;
    rdfs:label "dauer recovery inhibited" ;
    rdfs:subClassOf obo:WBPhenotype_0000127 .

obo:WBPhenotype_0000409
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any of its parts at different stages of the lifecycle, compared to control animals." ;
    oboInOwl:hasBroadSynonym "Vab" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000409" ;
    a owl:Class ;
    rdfs:label "organism morphology variable" ;
    rdfs:subClassOf obo:WBPhenotype_0000535 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#has_quality> ;
                    owl:someValuesFrom obo:PATO_0001227
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000410
    obo:IAO_0000115 "Animals lack the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000410" ;
    a owl:Class ;
    rdfs:label "no defecation cycle" ;
    rdfs:subClassOf obo:WBPhenotype_0000207 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035882
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000411
    obo:IAO_0000115 "Animals die as rigid, rod-like larva. In C. elegans this defect is often caused by the misspecification of the excretory duct cell." ;
    oboInOwl:hasBroadSynonym "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Let" ;
    oboInOwl:id "WBPhenotype:0000411" ;
    a owl:Class ;
    rdfs:label "rod like larval lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000035, obo:WBPhenotype_0000054 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000051 ;
                    owl:someValuesFrom obo:PATO_0001873
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000023
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000412
    obo:IAO_0000115 "Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000412" ;
    a owl:Class ;
    rdfs:label "octanol chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001448, obo:WBPhenotype_0001452 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050919
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_37868
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000413
    obo:IAO_0000115 "Pharyngeal muscle is immobilized resulting in lack of pumping or lack of response to external stimulation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000413" ;
    a owl:Class ;
    rdfs:label "pharyngeal muscle paralyzed" ;
    rdfs:subClassOf obo:WBPhenotype_0000980 .

obo:WBPhenotype_0000414
    obo:IAO_0000115 "The cell takes on a different identity from which it was initially committed." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000414" ;
    a owl:Class ;
    rdfs:label "cell fate transformation" ;
    rdfs:subClassOf obo:WBPhenotype_0000216 .

obo:WBPhenotype_0000415
    obo:IAO_0000115 "Animals exhibit variations in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control." ;
    oboInOwl:hasNarrowSynonym "necrotic cell death abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000415" ;
    a owl:Class ;
    rdfs:label "necrotic cell death variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000729 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0070265
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000416
    obo:IAO_0000115 "Variations in the generation of the nutrient protein produced by intestinal cells and secreted by them into the pseudocoelom, from which it can be shared with other tissues in the body compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "yolk synthesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "vitellogenin synthesis abnormal" ;
    oboInOwl:id "WBPhenotype:0000416" ;
    a owl:Class ;
    rdfs:label "yolk synthesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001093 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007296
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000417
    obo:IAO_0000115 "The process of physical partitioning and separation of a cell into daughter cells is abolished." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000417" ;
    a owl:Class ;
    rdfs:label "cell division failure" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051301
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000418
    obo:IAO_0000115 "The physical partitioning and separation of an intestinal cell into daughter cells is abolished." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000418" ;
    a owl:Class ;
    rdfs:label "intestinal cell division failure" ;
    rdfs:subClassOf obo:WBPhenotype_0000417 .

obo:WBPhenotype_0000419
    obo:IAO_0000115 "Animals die at the L3 stage of the life cycle." ;
    oboInOwl:hasBroadSynonym "Let", "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000419" ;
    a owl:Class ;
    rdfs:label "L3 lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000058, obo:WBPhenotype_0000116 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000035
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000420
    obo:IAO_0000115 "Animals respond to levamisole at a lower concentration or a shorter exposure compared to control animals. Levamisole is a cholinergic agonist." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "tetramisole hypersensitive" ;
    oboInOwl:id "WBPhenotype:0000420" ;
    a owl:Class ;
    rdfs:label "levamisole hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000845, obo:WBPhenotype_0001579 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_6432
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000421
    obo:IAO_0000115 "Animals fail to respond to the concentration of levamisole that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc." ;
    oboInOwl:hasBroadSynonym "Lev R" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "tetramisole resistant" ;
    oboInOwl:id "WBPhenotype:0000421" ;
    a owl:Class ;
    rdfs:label "levamisole resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000845, obo:WBPhenotype_0001578 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_6432
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000422
    obo:IAO_0000115 "Animals exhibit spasmodic muscle twitching superimposed on normal sinusoidal motion." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000422" ;
    a owl:Class ;
    rdfs:label "twitcher" ;
    rdfs:subClassOf obo:WBPhenotype_0001701 .

obo:WBPhenotype_0000423
    obo:IAO_0000115 "Any variation in the contractions of the muscles in the most anterior body region of the animal compared to control." ;
    oboInOwl:hasNarrowSynonym "head muscle contraction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000423" ;
    a owl:Class ;
    rdfs:label "head muscle contraction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000611 .

obo:WBPhenotype_0000424
    obo:IAO_0000115 "Any variation in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "antibody staining abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000424" ;
    a owl:Class ;
    rdfs:label "antibody staining variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000112 .

obo:WBPhenotype_0000425
    obo:IAO_0000115 "Any variation that results in a decrease in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000425" ;
    a owl:Class ;
    rdfs:label "antibody staining reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000424 .

obo:WBPhenotype_0000426
    obo:IAO_0000115 "Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000426" ;
    a owl:Class ;
    rdfs:label "antibody staining increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000424 .

obo:WBPhenotype_0000427
    obo:IAO_0000115 "Animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000427" ;
    a owl:Class ;
    rdfs:label "no cuticle" ;
    rdfs:subClassOf obo:WBPhenotype_0000201 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005755
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000428
    obo:IAO_0000115 "Adult animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000428" ;
    a owl:Class ;
    rdfs:label "no adult cuticle" ;
    rdfs:subClassOf obo:WBPhenotype_0000427 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002000
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:WBbt_0005755
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000429
    obo:IAO_0000115 "Any variation in the progression of the specialized structures of the animal which allow the successful transfer of sperm from one organism to another, compared to control." ;
    oboInOwl:hasNarrowSynonym "copulatory structure development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000429" ;
    a owl:Class ;
    rdfs:label "copulatory structure development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000624 .

obo:WBPhenotype_0000430
    obo:IAO_0000115 "Any variation in the progression of the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm over time from its formation to its mature structure compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "male copulatory structure development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000430" ;
    a owl:Class ;
    rdfs:label "male copulatory structure development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000429 .

obo:WBPhenotype_0000431
    obo:IAO_0000115 "Any variation in the progression of the specialized structures of a hermaphrodite which allow the successful transfer of sperm from a male, compared to control." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite copulatory structure development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000431" ;
    a owl:Class ;
    rdfs:label "hermaphrodite copulatory structure development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000429 .

obo:WBPhenotype_0000432
    obo:IAO_0000115 "Animals lack the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000432" ;
    a owl:Class ;
    rdfs:label "male copulatory structure absent" ;
    rdfs:subClassOf obo:WBPhenotype_0000430 .

obo:WBPhenotype_0000433
    obo:IAO_0000115 "Variations in the processes involving the production of new DNA strands compared to control." ;
    oboInOwl:hasNarrowSynonym "DNA synthesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000433" ;
    a owl:Class ;
    rdfs:label "DNA synthesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000732 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006260
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000434
    obo:IAO_0000115 "The developmental process by which a progressive change in the state of some part of an organism specifically contributing to its ability to form offspring is impaired." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000434" ;
    a owl:Class ;
    rdfs:label "sexual maturation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000624 .

obo:WBPhenotype_0000435
    obo:IAO_0000115 "OBSOLETE. Any change in the subcellular localization of a protein." ;
    obo:IAO_0100001 obo:WBPhenotype_0000436 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000435" ;
    a owl:Class ;
    rdfs:label "obsolete protein localization abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000436
    obo:IAO_0000115 "Any variation in the placement of a protein within in a cell or cellular compartment compared to control." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000435" ;
    oboInOwl:hasExactSynonym "protein localization abnormal" ;
    oboInOwl:hasNarrowSynonym "protein subcellular localization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000436" ;
    a owl:Class ;
    rdfs:label "protein subcellular localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001408 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0034613
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000437
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000033 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000437" ;
    a owl:Class ;
    rdfs:label "obsolete heterochronic defect" ;
    owl:deprecated true .

obo:WBPhenotype_0000438
    obo:IAO_0000115 "Variations that result in the deceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000438" ;
    a owl:Class ;
    rdfs:label "retarded heterochronic variations" ;
    rdfs:subClassOf obo:WBPhenotype_0000033 .

obo:WBPhenotype_0000439
    obo:IAO_0000115 "Variations that result in the acceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000439" ;
    a owl:Class ;
    rdfs:label "precocious heterochronic variations" ;
    rdfs:subClassOf obo:WBPhenotype_0000033 .

obo:WBPhenotype_0000440
    obo:IAO_0000115 "The structure made by the processes of the excretory canal cell is increased in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "long excretory canals" ;
    oboInOwl:id "WBPhenotype:0000440" ;
    a owl:Class ;
    rdfs:label "excretory canals long" ;
    rdfs:subClassOf obo:WBPhenotype_0000704 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000573
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005775
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000441
    obo:IAO_0000115 "Tails change shape and undergo retraction thereby forming a 'peloderan' or 'rounded' adult tail." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000441" ;
    a owl:Class ;
    rdfs:label "tail rounded" ;
    rdfs:subClassOf obo:WBPhenotype_0000073 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000411
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005741
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000442
    obo:IAO_0000115 "The developmental progression of a larva over time, from its formation to its mature structure is delayed compared to control. The larva is the early, immature form of an animal between hatching and adulthood." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000442" ;
    a owl:Class ;
    rdfs:label "larval development retarded" ;
    rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0000750 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000502
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000443
    obo:IAO_0000115 "Any variation in the appearance of the elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control." ;
    oboInOwl:hasNarrowSynonym "spicule morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000443" ;
    a owl:Class ;
    rdfs:label "spicule morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001024 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005312
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000444
    obo:IAO_0000115 "The length of the adult male tail, including the lateral fan and rays, is extended compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000444" ;
    a owl:Class ;
    rdfs:label "bursa elongated" ;
    rdfs:subClassOf obo:WBPhenotype_0000342 .

obo:WBPhenotype_0000445
    obo:IAO_0000115 "Males generate yolk, the nutrient protein, normally produced and secreted by hermaphrodite or female intestinal cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "vitellogenin synthesis in males" ;
    oboInOwl:id "WBPhenotype:0000445" ;
    a owl:Class ;
    rdfs:label "yolk synthesis in males" ;
    rdfs:subClassOf obo:WBPhenotype_0000416 .

obo:WBPhenotype_0000446
    obo:IAO_0000115 "Animals execute extra larval molts compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000446" ;
    a owl:Class ;
    rdfs:label "supernumerary molt" ;
    rdfs:subClassOf obo:WBPhenotype_0002041 .

obo:WBPhenotype_0000447
    obo:IAO_0000115 "Variations in the progression of an animal over time from the end of larval stage to a mature adult compared to control animals." ;
    oboInOwl:hasNarrowSynonym "adult development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000447" ;
    a owl:Class ;
    rdfs:label "adult development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000049 .

obo:WBPhenotype_0000448
    obo:IAO_0000115 "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time in adults compared to control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "adult cuticle development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000448" ;
    a owl:Class ;
    rdfs:label "adult cuticle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000447 .

obo:WBPhenotype_0000449
    obo:IAO_0000115 "A duplication of the developmental program that forms the adult-type rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000449" ;
    a owl:Class ;
    rdfs:label "second adult cuticle" ;
    rdfs:subClassOf obo:WBPhenotype_0000448 .

obo:WBPhenotype_0000450
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000506 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000450" ;
    a owl:Class ;
    rdfs:label "obsolete swollen male tail" ;
    owl:deprecated true .

obo:WBPhenotype_0000451
    obo:IAO_0000115 "Any irregular swelling in discrete regions of the head." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000451" ;
    a owl:Class ;
    rdfs:label "head protrusion" ;
    rdfs:subClassOf obo:WBPhenotype_0000071 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001598
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005739
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000452
    obo:IAO_0000115 "Any irregular swelling in discrete regions of the tail, usually caused by a local defect in the normal smooth tapering of the hypodermis and/or cuticle (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000452" ;
    a owl:Class ;
    rdfs:label "tail protrusions" ;
    rdfs:subClassOf obo:WBPhenotype_0000073 .

obo:WBPhenotype_0000453
    obo:IAO_0000115 "Any irregular swelling in discrete regions of the body region between the head and the tail." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000453" ;
    a owl:Class ;
    rdfs:label "body protrusions" ;
    rdfs:subClassOf obo:WBPhenotype_0000072 .

obo:WBPhenotype_0000454
    obo:IAO_0000115 "The anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring)of the body appears distorted, usually due to uncharacteristic winding." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000454" ;
    a owl:Class ;
    rdfs:label "head twisted" ;
    rdfs:subClassOf obo:WBPhenotype_0000071 .

obo:WBPhenotype_0000455
    obo:IAO_0000115 "Animals exhibit abrupt transitions while traveling from one location to another." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000455" ;
    a owl:Class ;
    rdfs:label "jerky movement" ;
    rdfs:subClassOf obo:WBPhenotype_0001701 .

obo:WBPhenotype_0000456
    obo:IAO_0000115 "Variations in characteristic response with respect to perception or transmission of a touch stimulus compared to responses in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "touch insensitive" ;
    oboInOwl:id "WBPhenotype:0000456" ;
    a owl:Class ;
    rdfs:label "touch resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0000457
    obo:IAO_0000115 "Animals show enhanced suceptibility to deprivation of nourishment, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000457" ;
    a owl:Class ;
    rdfs:label "organism starvation hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000147 .

obo:WBPhenotype_0000458
    obo:IAO_0000115 "Animals show enhanced tolerance to deprivation of nourishment, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000458" ;
    a owl:Class ;
    rdfs:label "starvation resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000147 .

obo:WBPhenotype_0000459
    obo:IAO_0000115 "Animals exhibit variations in their response to any chemical substance that is used for killing pests, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "pesticide response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000459" ;
    a owl:Class ;
    rdfs:label "pesticide response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_25944
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000460
    obo:IAO_0000115 "Animals exhibit variations in their response to paraquat compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "paraquat response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "methyl viologen response abnormal" ;
    oboInOwl:id "WBPhenotype:0000460" ;
    a owl:Class ;
    rdfs:label "paraquat response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000459, obo:WBPhenotype_0001620 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1901562
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000461
    obo:IAO_0000115 "Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000461" ;
    a owl:Class ;
    rdfs:label "paraquat resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000460 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_34905
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000462
    obo:IAO_0000115 "Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasBroadSynonym "reactive oxygen species hypersensitive" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000462" ;
    a owl:Class ;
    rdfs:label "paraquat hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000460 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_34905
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000463
    obo:IAO_0000115 "Animals exhibit variations in processes that are responsible for chemical changes compared to control animals. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." ;
    oboInOwl:hasNarrowSynonym "metabolic pathway abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000463" ;
    a owl:Class ;
    rdfs:label "metabolic pathway variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0000464
    obo:IAO_0000115 "Animals exhibit variations in their response to oxygen compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "oxygen response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000464" ;
    a owl:Class ;
    rdfs:label "oxygen response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_25805
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000465
    obo:IAO_0000115 "Animals fail to respond to the high concentrations of oxygen that elicit a response in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000465" ;
    a owl:Class ;
    rdfs:label "high oxygen resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000464 .

obo:WBPhenotype_0000466
    obo:IAO_0000115 "Animals respond to hyperoxic (high oxygen tension) conditions after a shorter exposure time compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000466" ;
    a owl:Class ;
    rdfs:label "high oxygen hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000464 .

obo:WBPhenotype_0000467
    obo:IAO_0000115 "Animals exhibit an increase in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000467" ;
    a owl:Class ;
    rdfs:label "age associated fluorescence increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001009 .

obo:WBPhenotype_0000468
    obo:IAO_0000115 "Animals exhibit a decrease in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000468" ;
    a owl:Class ;
    rdfs:label "age associated fluorescence reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001009 .

obo:WBPhenotype_0000469
    obo:IAO_0000115 "The daughters of the Q neuroblasts exhibit variation in their characteristic movements compared to control animals." ;
    oboInOwl:hasNarrowSynonym "Q neuroblast lineage migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000469" ;
    a owl:Class ;
    rdfs:label "Q neuroblast lineage migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001140 .

obo:WBPhenotype_0000470
    obo:IAO_0000115 "Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo compared to control animals." ;
    oboInOwl:hasNarrowSynonym "HSN migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000470" ;
    a owl:Class ;
    rdfs:label "HSN migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001229 .

obo:WBPhenotype_0000471
    obo:IAO_0000115 "Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo compared to control animals." ;
    oboInOwl:hasNarrowSynonym "ALM migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000471" ;
    a owl:Class ;
    rdfs:label "ALM migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001520 .

obo:WBPhenotype_0000472
    obo:IAO_0000115 "Animals lack the early blast cells that give rise to the gut tissue (Wormatlas)." ;
    oboInOwl:hasExactSynonym "gutless" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000472" ;
    a owl:Class ;
    rdfs:label "endoderm absent" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 .

obo:WBPhenotype_0000473
    obo:IAO_0000115 "Animals become increasingly sluggish/immobilized as they age." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000473" ;
    a owl:Class ;
    rdfs:label "progressive paralysis" ;
    rdfs:subClassOf obo:WBPhenotype_0000644 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000763
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#has_quality> ;
                    owl:someValuesFrom obo:PATO_0001818
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000474
    obo:IAO_0000115 "Any variation in the connection of the cell(s) whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control." ;
    oboInOwl:hasBroadSynonym "Mua" ;
    oboInOwl:hasNarrowSynonym "muscle attachment abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000474" ;
    a owl:Class ;
    rdfs:label "muscle attachment variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000622 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016203
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000475
    obo:IAO_0000115 "Animals fail to establish or maintain the connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000475" ;
    a owl:Class ;
    rdfs:label "muscle detached" ;
    rdfs:subClassOf obo:WBPhenotype_0000474 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001453
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:WBbt_0003675
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000476
    obo:IAO_0000115 "The connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues diminishes over time." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000476" ;
    a owl:Class ;
    rdfs:label "progressive muscle detachment" ;
    rdfs:subClassOf obo:WBPhenotype_0000474 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001453
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:WBbt_0003675
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#has_quality> ;
                    owl:someValuesFrom obo:PATO_0001818
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000477
    obo:IAO_0000115 "Any variation in the change in direction of a wave of light after passage through the nucleolus compared to control. The nucleolus is a small dense body in the nucleus." ;
    oboInOwl:hasNarrowSynonym "nucleolus refraction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000477" ;
    a owl:Class ;
    rdfs:label "nucleolus refraction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000722 .

obo:WBPhenotype_0000478
    obo:IAO_0000115 "Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature." ;
    oboInOwl:hasNarrowSynonym "isothermal tracking behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "thermotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0000478" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "isothermal tracking behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002513 .

obo:WBPhenotype_0000479
    obo:IAO_0000115 "Eggs show deficiencies in chroma resulting in increased translucency." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000479" ;
    a owl:Class ;
    rdfs:label "egg pale" ;
    rdfs:subClassOf obo:WBPhenotype_0000970, obo:WBPhenotype_0001261 .

obo:WBPhenotype_0000480
    obo:IAO_0000115 "Failure to execute the characteristic response to pyrazine as defined by control animals. In C. elegans pyrazine is typically an attractant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000480" ;
    a owl:Class ;
    rdfs:label "pyrazine chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001474 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_30953
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000481
    obo:IAO_0000115 "Any variation in the directed movement of an animal in response to chemical repellants as defined by control animals." ;
    oboInOwl:hasNarrowSynonym "negative chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "chemical avoidance abnormal", "chemoaversion abnormal" ;
    oboInOwl:id "WBPhenotype:0000481" ;
    a owl:Class ;
    rdfs:label "negative chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001434 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050919
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000482
    obo:IAO_0000115 "Failure to execute the characteristic response to garlic as defined by control animals. In C. elegans, garlic is typically a repellent." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000482" ;
    a owl:Class ;
    rdfs:label "garlic chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001449, obo:WBPhenotype_0001451 .

obo:WBPhenotype_0000483
    obo:IAO_0000115 "Animals lack the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000483" ;
    a owl:Class ;
    rdfs:label "no gut granules" ;
    rdfs:subClassOf obo:WBPhenotype_0000103 .

obo:WBPhenotype_0000484
    obo:IAO_0000115 "The organism's size during the embryonic developmental stage is decreased compared to that observed in control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000484" ;
    a owl:Class ;
    rdfs:label "embryo small" ;
    rdfs:subClassOf obo:WBPhenotype_0001136 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000587
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000003
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000485
    obo:IAO_0000115 "The survival of animals in the alternative larval stage which they enter when placed under conditions of environmental stress is reduced." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "reduced dauer survival" ;
    oboInOwl:id "WBPhenotype:0000485" ;
    a owl:Class ;
    rdfs:label "dauer death increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002527 .

obo:WBPhenotype_0000486
    obo:IAO_0000115 "Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000486" ;
    a owl:Class ;
    rdfs:label "colchicine hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_23359
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000487
    obo:IAO_0000115 "Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000487" ;
    a owl:Class ;
    rdfs:label "colchicine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_23359
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000488
    obo:IAO_0000115 "Animals respond to chloroquine at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000488" ;
    a owl:Class ;
    rdfs:label "chloroquine hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_3638
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000489
    obo:IAO_0000115 "Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000489" ;
    a owl:Class ;
    rdfs:label "chloroquine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_3638
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000490
    obo:IAO_0000115 "The components of the feeding organ fail to be arranged in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000490" ;
    a owl:Class ;
    rdfs:label "pharynx disorganized" ;
    rdfs:subClassOf obo:WBPhenotype_0000707 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000937
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003681
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000491
    obo:IAO_0000115 "Any observed morphological defects of the isthmus." ;
    oboInOwl:hasNarrowSynonym "isthmus morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "isthmus malformed" ;
    oboInOwl:id "WBPhenotype:0000491" ;
    a owl:Class ;
    rdfs:label "isthmus morphology defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000709 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003734
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000492
    obo:IAO_0000115 "Any variation in the form, structure or composition of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "corpus morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "corpus malformed" ;
    oboInOwl:id "WBPhenotype:0000492" ;
    a owl:Class ;
    rdfs:label "corpus morphology defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000709 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003733
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000493
    obo:IAO_0000115 "Any variation in the form, structure or composition of the first pharyngeal bulb compared to control." ;
    oboInOwl:hasNarrowSynonym "metacorpus morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "metacarpas malformed" ;
    oboInOwl:id "WBPhenotype:0000493" ;
    a owl:Class ;
    rdfs:label "metacorpus morphology defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000709 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003711
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000494
    obo:IAO_0000115 "Cessation of development that normally occurs in C. elegans 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000494" ;
    a owl:Class ;
    rdfs:label "two fold arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000779 .

obo:WBPhenotype_0000495
    obo:IAO_0000115 "Animals have finger-like sensory sensilla (rays) that are present in places they are normally not found, when compared to the location in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000495" ;
    a owl:Class ;
    rdfs:label "ray ectopic" ;
    rdfs:subClassOf obo:WBPhenotype_0000199, obo:WBPhenotype_0002498 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006941
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000496
    obo:IAO_0000115 "Males lack the specialized sensory papillae that lie along the posterior half of the body." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000496" ;
    a owl:Class ;
    rdfs:label "male postdeirid sensilla absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001008 .

obo:WBPhenotype_0000497
    obo:IAO_0000115 "Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism gamma ray response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000497" ;
    a owl:Class ;
    rdfs:label "organism gamma ray response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000686 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010332
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000498
    obo:IAO_0000115 "Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "methyl methanesulfonate response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "MMS response abnormal" ;
    oboInOwl:id "WBPhenotype:0000498" ;
    a owl:Class ;
    rdfs:label "methyl methanesulfonate response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_25255
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000499
    obo:IAO_0000115 "Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "ethyl methanesulfonate response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "EMS response abnormal" ;
    oboInOwl:id "WBPhenotype:0000499" ;
    a owl:Class ;
    rdfs:label "ethyl methanesulfonate response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_23994
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000500
    obo:IAO_0000115 "Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000500" ;
    a owl:Class ;
    rdfs:label "acetylcholinesterase inhibitor hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001290 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_38462
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000501
    obo:IAO_0000115 "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the left-handed direction. In liquid media, wave propogation is helical rather than planar." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Rol" ;
    oboInOwl:id "WBPhenotype:0000501" ;
    a owl:Class ;
    rdfs:label "left handed roller" ;
    rdfs:subClassOf obo:WBPhenotype_0000645 .

obo:WBPhenotype_0000502
    obo:IAO_0000115 "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the right-handed direction. In liquid media, wave propogation is helical rather than planar." ;
    oboInOwl:hasBroadSynonym "Rol" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000502" ;
    a owl:Class ;
    rdfs:label "right handed roller" ;
    rdfs:subClassOf obo:WBPhenotype_0000645 .

obo:WBPhenotype_0000503
    obo:IAO_0000115 "Any variation in the multiple rounds of DNA replication that take place without chromosome condensation, segregation or cytokinesis compared to control. In C. elegans this process is normally seen in intestinal nuclei during each larval lethargus which results in adult intestinal nuclei with 32 copies (32C) of each chromosome(Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "endoreduplication abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000503" ;
    a owl:Class ;
    rdfs:label "endoreduplication variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000732 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042023
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000504
    obo:IAO_0000115 "Any variation in the process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei, compared to control." ;
    oboInOwl:hasNarrowSynonym "nuclear division abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "karyokinesis abnormal" ;
    oboInOwl:id "WBPhenotype:0000504" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "nuclear division variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000280
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000505
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of any of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control animals. In C. elegans, nine bilateral rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye." ;
    oboInOwl:hasBroadSynonym "Ram" ;
    oboInOwl:hasNarrowSynonym "male ray morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000505" ;
    a owl:Class ;
    rdfs:label "male ray morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000299, obo:WBPhenotype_0001358 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006941
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000506
    obo:IAO_0000115 "The adult male tail, including the lateral fan and rays, appears bloated or distended." ;
    oboInOwl:hasExactSynonym "swollen male tail" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000506" ;
    a owl:Class ;
    rdfs:label "bursa swollen" ;
    rdfs:subClassOf obo:WBPhenotype_0000342 .

obo:WBPhenotype_0000507
    obo:IAO_0000115 "Animals exhibit variations in the amount of acetylcholine compared to control animals at a defined stage. Acetylcholine is the acetic acid ester of the organic base choline." ;
    oboInOwl:hasNarrowSynonym "acetylcholine levels abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000507" ;
    a owl:Class ;
    rdfs:label "acetylcholine levels variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_15355
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000508
    obo:IAO_0000115 "Animals exhibit a decrease in the regulated breakdown of mRNA transcripts in which an amino-acid codon has changed to a premature stop codon and the 3 prime end is not protected by a poly(A) tail." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000508" ;
    a owl:Class ;
    rdfs:label "nonsense mRNA accumulation" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000184
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000509
    obo:IAO_0000115 "Variation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa." ;
    oboInOwl:hasNarrowSynonym "sperm pseudopod abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000509" ;
    a owl:Class ;
    rdfs:label "sperm pseudopod variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000388 .

obo:WBPhenotype_0000510
    obo:IAO_0000115 "The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000287" ;
    oboInOwl:hasNarrowSynonym "vulval invagination L4 abnormal", "vulval invagination abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "vulval invagination L4 variant" ;
    oboInOwl:id "WBPhenotype:0000510" ;
    a owl:Class ;
    rdfs:label "vulval invagination variant L4" ;
    rdfs:subClassOf obo:WBPhenotype_0000695, obo:WBPhenotype_0000699 .

obo:WBPhenotype_0000511
    obo:IAO_0000115 "Variations in the directed movement of the nucleus to a specific location within a cell compared to control." ;
    oboInOwl:hasNarrowSynonym "nuclear positioning abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "nuclear migration variant" ;
    oboInOwl:id "WBPhenotype:0000511" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "nuclear positioning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0001344 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007097
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000512
    obo:IAO_0000115 "Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position." ;
    oboInOwl:hasNarrowSynonym "VNC nuclear positioning abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "VNC nuclear migration variant" ;
    oboInOwl:id "WBPhenotype:0000512" ;
    a owl:Class ;
    rdfs:label "VNC nuclear positioning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000511 .

obo:WBPhenotype_0000513
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000315 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000513" ;
    a owl:Class ;
    rdfs:label "obsolete touch response abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000514
    obo:IAO_0000115 "When prodded on the head, worm contracts and then relaxes along its entire body without moving backwards, compared to a control worm which contracts its anterior end and backs away in response to prodding." ;
    oboInOwl:hasBroadSynonym "Rbr" ;
    oboInOwl:hasExactSynonym "rubberband" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000514" ;
    a owl:Class ;
    rdfs:label "rubber band" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0000515
    obo:IAO_0000115 "Variations in any process whose specific outcome is the development and/or maintenance of the ventral nerve cord." ;
    oboInOwl:hasNarrowSynonym "ventral nerve cord development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000515" ;
    a owl:Class ;
    rdfs:label "ventral nerve cord development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000945 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005829
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000516
    obo:IAO_0000115 "The longitudinal nerve cord of the midbody region, connecting the nerve ring and tail ganglia, is not arranged in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000516" ;
    a owl:Class ;
    rdfs:label "ventral cord disorganized" ;
    rdfs:subClassOf obo:WBPhenotype_0000976 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000937
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005829
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000517
    obo:IAO_0000115 "Variations in the specific actions or reactions in response to external or internal stimuli compared to that observed in control animals." ;
    oboInOwl:hasExactSynonym "behavior abnormal", "behavior variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000517" ;
    a owl:Class ;
    rdfs:label "behavior phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007610
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000518
    obo:IAO_0000115 "Variations in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasExactSynonym "development abnormal", "development variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000518" ;
    a owl:Class ;
    rdfs:label "development phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0032502
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000519
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals." ;
    oboInOwl:hasExactSynonym "physiology abnormal", "physiology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000519" ;
    a owl:Class ;
    rdfs:label "physiology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008150
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000520
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any of its parts compared to control animals." ;
    oboInOwl:hasExactSynonym "morphology abnormal", "morphology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000520" ;
    a owl:Class ;
    rdfs:label "morphology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000521
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency." ;
    oboInOwl:hasExactSynonym "pigmentation abnormal", "pigmentation variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000521" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "pigmentation phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002247
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000522
    obo:IAO_0000115 "Variations in the specific actions or reactions of a certain defined body area of an animal in response to external or internal stimuli compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism region behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000522" ;
    a owl:Class ;
    rdfs:label "organism region behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 .

obo:WBPhenotype_0000523
    obo:IAO_0000115 "Animals exhibit variations in their response to a specific chemical compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "chemical response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000523" ;
    a owl:Class ;
    rdfs:label "chemical response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042221
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000524
    obo:IAO_0000115 "Animals exhibit variations in their response to bleach compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "bleach response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000524" ;
    a owl:Class ;
    rdfs:label "bleach response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001379 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1901530
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000525
    obo:IAO_0000115 "Variations in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in control organisms." ;
    oboInOwl:hasNarrowSynonym "organism behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000525" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organism behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000517 .

obo:WBPhenotype_0000526
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a cell." ;
    oboInOwl:hasExactSynonym "cell pigmentation abnormal", "cell pigmentation variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000526" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell pigmentation phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000521 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002247
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004017
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000527
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism." ;
    oboInOwl:hasExactSynonym "organism pigmentation abnormal", "organism pigmentation variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Abnormal Coloration" ;
    oboInOwl:id "WBPhenotype:0000527" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organism pigmentation phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000521 .

obo:WBPhenotype_0000528
    obo:IAO_0000115 "Variations in the progression of the overall structure or appearance of a discrete region of an animal's anatomy over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body region development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000528" ;
    a owl:Class ;
    rdfs:label "body region development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005738
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000529
    obo:IAO_0000115 "Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals." ;
    oboInOwl:hasNarrowSynonym "cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000529" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000518 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048468
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000530
    obo:IAO_0000115 "Any variation in the progression of an organismal system from its formation to the mature structure when compared to control animals." ;
    oboInOwl:hasNarrowSynonym "organ system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000530" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organ system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000518 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005746
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000531
    obo:IAO_0000115 "Any variation in the progression of a worm at any time from its fertilization to adulthood compared to control." ;
    oboInOwl:hasNarrowSynonym "organism development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000531" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organism development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000518 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0007833
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000532
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a discrete region of their anatomy compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body region morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000532" ;
    a owl:Class ;
    rdfs:label "body region morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000535 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005738
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000533
    obo:IAO_0000115 "Any variation in the form or composition of the basic structural and functional unit of all organisms compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
    oboInOwl:hasNarrowSynonym "cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000533" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000520 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004017
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000534
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system." ;
    oboInOwl:hasNarrowSynonym "organ system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000534" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organ system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000520 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005746
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000535
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." ;
    oboInOwl:hasBroadSynonym "Bmd" ;
    oboInOwl:hasNarrowSynonym "organism morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "body morphology defects" ;
    oboInOwl:id "WBPhenotype:0000535" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organism morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000520 .

obo:WBPhenotype_0000536
    obo:IAO_0000115 "Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasExactSynonym "cell physiology abnormal", "cell physiology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000536" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell physiology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000519 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0004017
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000537
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000584 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000537" ;
    a owl:Class ;
    rdfs:label "obsolete synaptic input abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000538
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000584 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000538" ;
    a owl:Class ;
    rdfs:label "obsolete synaptic output abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000539
    obo:IAO_0000115 "Variations in the progression of the anatomical structures that consist of processes of ventral cord motor neurons that send commissures to the dorsal side, as well as processes of certain head and tail neurons, over time from initial formation to mature structure compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "dorsal nerve cord development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000539" ;
    a owl:Class ;
    rdfs:label "dorsal nerve cord development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000945 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006750
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000540
    obo:IAO_0000115 "Variations in the progression of the process extension from the muscle belly by which the muscle cells reach to the nerve cords to obtain innervation over time from initial formation to mature structure compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "muscle arm development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "muscle arm extension variant" ;
    oboInOwl:id "WBPhenotype:0000540" ;
    a owl:Class ;
    rdfs:label "muscle arm development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000087 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:GO_0036194
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000541
    obo:IAO_0000115 "Axon tracts fail to complete the connection between nerve cords. In C. elegans, these tracts grow circumferentially around the animal, completing the connection between the ventral and dorsal nerve cords." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000541" ;
    a owl:Class ;
    rdfs:label "cord commissures fail to reach target" ;
    rdfs:subClassOf obo:WBPhenotype_0000014 .

obo:WBPhenotype_0000542
    obo:IAO_0000115 "Animals exhibit an increased girth compared to a control animal of the same developmental stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "increased girth", "thick" ;
    oboInOwl:id "WBPhenotype:0000542" ;
    a owl:Class ;
    rdfs:label "fat" ;
    rdfs:subClassOf obo:WBPhenotype_0001727 .

obo:WBPhenotype_0000543
    obo:IAO_0000115 "Forward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves forward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000543" ;
    a owl:Class ;
    rdfs:label "forward kinker" ;
    rdfs:subClassOf obo:WBPhenotype_0000002 .

obo:WBPhenotype_0000544
    obo:IAO_0000115 "Backward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves backward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000544" ;
    a owl:Class ;
    rdfs:label "backward kinker" ;
    rdfs:subClassOf obo:WBPhenotype_0000002 .

obo:WBPhenotype_0000545
    obo:IAO_0000115 "Eggs are retained in the uterus at a later stage when compared with control animals." ;
    oboInOwl:hasBroadSynonym "Ret" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "late eggs laid" ;
    oboInOwl:id "WBPhenotype:0000545" ;
    a owl:Class ;
    rdfs:label "egg retention" ;
    rdfs:subClassOf obo:WBPhenotype_0000006 .

obo:WBPhenotype_0000546
    obo:IAO_0000115 "Eggs are laid at an earlier stage of development when compared with control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000546" ;
    a owl:Class ;
    rdfs:label "early eggs laid" ;
    rdfs:subClassOf obo:WBPhenotype_0000005, obo:WBPhenotype_0000439 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000694
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000547
    obo:IAO_0000115 "Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Eat" ;
    oboInOwl:id "WBPhenotype:0000547" ;
    a owl:Class ;
    rdfs:label "starved" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0000548
    obo:IAO_0000115 "Progressive degeneration of muscle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000548" ;
    a owl:Class ;
    rdfs:label "muscle dystrophy" ;
    rdfs:subClassOf obo:WBPhenotype_0000611 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001780
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003675
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000549
    obo:IAO_0000115 "Progressive degeneration of the head muscle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000549" ;
    a owl:Class ;
    rdfs:label "head muscle dystrophy" ;
    rdfs:subClassOf obo:WBPhenotype_0000548, obo:WBPhenotype_0001002 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001780
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006761
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000550
    obo:IAO_0000115 "Progressive degeneration of muscle along the body wall." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "body wall muscle dystrophy" ;
    oboInOwl:id "WBPhenotype:0000550" ;
    a owl:Class ;
    rdfs:label "body muscle dystrophy" ;
    rdfs:subClassOf obo:WBPhenotype_0000548, obo:WBPhenotype_0000596 .

obo:WBPhenotype_0000551
    obo:IAO_0000115 "Animals exhibit variations in the rate of sharp head to tail turns compared to control animals." ;
    oboInOwl:hasNarrowSynonym "omega turns abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000551" ;
    a owl:Class ;
    rdfs:label "omega turns variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002311 .

obo:WBPhenotype_0000552
    obo:IAO_0000115 "Animals exhibit variations in the amount of GABA compared to control animals at a defined stage." ;
    oboInOwl:hasNarrowSynonym "GABA levels abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000552" ;
    a owl:Class ;
    rdfs:label "GABA levels variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_16865
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000553
    obo:IAO_0000115 "Animals exhibit a weak and abnormal birefringency pattern in muscle fibers when examined using polarized optics." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000714" ;
    oboInOwl:hasExactSynonym "Dim", "disorganized muscle" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "muscle birefringence abnormal" ;
    oboInOwl:id "WBPhenotype:0000553" ;
    a owl:Class ;
    rdfs:comment "Disorganized muscle fibers display a weak and abnormal birefringency pattern when examined using polarized optics." ;
    rdfs:label "muscle birefringence variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000926 .

obo:WBPhenotype_0000554
    obo:IAO_0000115 "Any variation in the ability to adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000554" ;
    a owl:Class ;
    rdfs:label "hypoosmotic shock hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000041 .

obo:WBPhenotype_0000555
    obo:IAO_0000115 "Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control." ;
    oboInOwl:hasNarrowSynonym "drug adaptation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000555" ;
    a owl:Class ;
    rdfs:label "drug adaptation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0000556
    obo:IAO_0000115 "Animals show variations in their decreased responsiveness after prolonged or repeated exposure to dopamine compared to that in control." ;
    oboInOwl:hasNarrowSynonym "dopamine adaptation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000556" ;
    a owl:Class ;
    rdfs:label "dopamine adaptation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000555 .

obo:WBPhenotype_0000557
    obo:IAO_0000115 "Animals do not exhibit decreased responsiveness after prolonged or repeated exposure to dopamine." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000557" ;
    a owl:Class ;
    rdfs:label "dopamine adaptation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000556 .

obo:WBPhenotype_0000558
    obo:IAO_0000115 "Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "calcium channel modulator response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000558" ;
    a owl:Class ;
    rdfs:label "calcium channel modulator response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0001833, obo:WBPhenotype_0002170 .

obo:WBPhenotype_0000559
    obo:IAO_0000115 "Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000559" ;
    a owl:Class ;
    rdfs:label "calcium channel modulator hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0000558 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_38808
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000560
    obo:IAO_0000115 "Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000560" ;
    a owl:Class ;
    rdfs:label "calcium channel modulator resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0000558 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_38808
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000561
    obo:IAO_0000115 "The heads of animals fail to respond to the concentration of levamisole that elicits a response in control animals. In C. elegans, heads contract at >10uM for intact animals and >1uM for cut animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "head tetramisole resistant" ;
    oboInOwl:id "WBPhenotype:0000561" ;
    a owl:Class ;
    rdfs:label "head levamisole resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000421 .

obo:WBPhenotype_0000562
    obo:IAO_0000115 "The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "body tetramisole resistant" ;
    oboInOwl:id "WBPhenotype:0000562" ;
    a owl:Class ;
    rdfs:label "body levamisole resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000421 .

obo:WBPhenotype_0000563
    obo:IAO_0000115 "The whole body undergoes longitudinal shortening in response to head touch or tail touch (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000563" ;
    a owl:Class ;
    rdfs:label "shrinker" ;
    rdfs:subClassOf obo:WBPhenotype_0001701 .

obo:WBPhenotype_0000564
    obo:IAO_0000115 "Muscle contractions that make up the defecation motor program are repeated before the onset of the next cycle unlike in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000564" ;
    a owl:Class ;
    rdfs:label "echo defecation cycle" ;
    rdfs:subClassOf obo:WBPhenotype_0000207 .

obo:WBPhenotype_0000565
    obo:IAO_0000115 "The body of an animal assumes a coil-like shape when it attempts to move." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "curler" ;
    oboInOwl:id "WBPhenotype:0000565" ;
    a owl:Class ;
    rdfs:label "coiler" ;
    rdfs:subClassOf obo:WBPhenotype_0002297, obo:WBPhenotype_0004017 .

obo:WBPhenotype_0000566
    obo:IAO_0000115 "A coiling body that bends ventrally." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ventral curler" ;
    oboInOwl:id "WBPhenotype:0000566" ;
    a owl:Class ;
    rdfs:label "ventral coiler" ;
    rdfs:subClassOf obo:WBPhenotype_0000565 .

obo:WBPhenotype_0000567
    obo:IAO_0000115 "A coiling body that bends dorsally." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "dorsal curler" ;
    oboInOwl:id "WBPhenotype:0000567" ;
    a owl:Class ;
    rdfs:label "dorsal coiler" ;
    rdfs:subClassOf obo:WBPhenotype_0000565 .

obo:WBPhenotype_0000568
    obo:IAO_0000115 "Animals display variations in the structure or organization of the components of the axon, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "axon ultrastructure abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000568" ;
    a owl:Class ;
    rdfs:label "axon ultrastructure variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000180 .

obo:WBPhenotype_0000569
    obo:IAO_0000115 "Animals display markedly swollen areas along their axons, which are larger than synaptic varicosities in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000569" ;
    a owl:Class ;
    rdfs:label "axon varicosities" ;
    rdfs:subClassOf obo:WBPhenotype_0000568 .

obo:WBPhenotype_0000570
    obo:IAO_0000115 "Axons of animals contain flattened membrane-bound compartments. In C. elegans, these cisternae-like structures are typically absent." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000570" ;
    a owl:Class ;
    rdfs:label "axon cisternae" ;
    rdfs:subClassOf obo:WBPhenotype_0000568 .

obo:WBPhenotype_0000571
    obo:IAO_0000115 "Axons of animals exhibit variations in the gross structure or organization of its spherical, membrane-bound, fluid-filled organelles, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "abnormal axon vesicle" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000571" ;
    a owl:Class ;
    rdfs:label "axon vesicle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000568 .

obo:WBPhenotype_0000572
    obo:IAO_0000115 "Any variation in the processes that govern the extension of neuronal projections." ;
    oboInOwl:hasNarrowSynonym "neuronal outgrowth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000572" ;
    a owl:Class ;
    rdfs:label "neuronal outgrowth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000816 .

obo:WBPhenotype_0000573
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0000633, obo:WBPhenotype_0001398 ;
    oboInOwl:hasNarrowSynonym "neuronal branching abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000573" ;
    a owl:Class ;
    rdfs:label "obsolete neuronal branching variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000574
    obo:IAO_0000115 "The structure made by the processes of the excretory canal cell is reduced in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000574" ;
    a owl:Class ;
    rdfs:label "excretory canal short" ;
    rdfs:subClassOf obo:WBPhenotype_0000704 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000574
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005775
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000575
    obo:IAO_0000115 "Animals exhibit variations in a physical or chemical process required for organs or tissues to carry out their normal functions or for their ability to perceive and respond to stimuli compared to control." ;
    oboInOwl:hasExactSynonym "organ system physiology abnormal", "organ system physiology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000575" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organ system physiology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000519 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005746
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000576
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli." ;
    oboInOwl:hasExactSynonym "organism physiology abnormal", "organism physiology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000576" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organism physiology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000519 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0007833
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000577
    obo:IAO_0000115 "Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control." ;
    oboInOwl:hasNarrowSynonym "organism homeostasis metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000577" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organism homeostasis metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000576 .

obo:WBPhenotype_0000578
    obo:IAO_0000115 "Variations in the progression of a discrete axis of an animal's anatomy over time, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body axis development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000578" ;
    a owl:Class ;
    rdfs:label "body axis development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000528 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005768
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000579
    obo:IAO_0000115 "Variations in the progression of the overall structure or appearance of any anterior/posterior section of an animal's anatomy over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "organism segment development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000579" ;
    a owl:Class ;
    rdfs:label "organism segment development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 .

obo:WBPhenotype_0000580
    obo:IAO_0000115 "Variations in the specific actions or reactions of a certain body region of an animal in response to external or internal stimuli compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism segment behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000580" ;
    a owl:Class ;
    rdfs:label "organism segment behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000522 .

obo:WBPhenotype_0000581
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a discrete axis (dorsal/ventral/anterior/posterior/transverse) of their anatomy, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body axis morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000581" ;
    a owl:Class ;
    rdfs:label "body axis morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000532 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005768
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000582
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any anterior/posterior section of their anatomy compared to control animals." ;
    oboInOwl:hasNarrowSynonym "organism segment morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000582" ;
    a owl:Class ;
    rdfs:label "organism segment morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000535 .

obo:WBPhenotype_0000583
    obo:IAO_0000115 "Worms are shorter and stouter than control animals at the same developmental stage." ;
    oboInOwl:hasBroadSynonym "Dpy" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000583" ;
    a owl:Class ;
    rdfs:label "dumpy" ;
    rdfs:subClassOf obo:WBPhenotype_0001726, obo:WBPhenotype_0001727 .

obo:WBPhenotype_0000584
    obo:IAO_0000115 "Any variation in the process of communication across a synapse between a neuron and a target cell (neuron, muscle, or secretory cell) compared to control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000537", "WBPhenotype:0000538" ;
    oboInOwl:hasExactSynonym "synaptic input variant", "synaptic output variant" ;
    oboInOwl:hasNarrowSynonym "synaptic input abnormal", "synaptic output abnormal", "synaptic transmission abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000584" ;
    a owl:Class ;
    rdfs:label "synaptic transmission variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002020 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007268
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000585
    obo:IAO_0000115 "Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control." ;
    oboInOwl:hasNarrowSynonym "cell homeostasis metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000585" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell homeostasis metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0000586
    obo:IAO_0000115 "Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000586" ;
    a owl:Class ;
    rdfs:label "bleach hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000524 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_29222
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000587
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0002072 ;
    oboInOwl:hasNarrowSynonym "lectin staining abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000587" ;
    a owl:Class ;
    rdfs:label "obsolete lectin staining variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000588
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:hasNarrowSynonym "no male abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000588" ;
    a owl:Class ;
    rdfs:comment "This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype." ;
    rdfs:label "obsolete no male variantity scored" ;
    owl:deprecated true .

obo:WBPhenotype_0000589
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:hasNarrowSynonym "no hermaphrodite abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000589" ;
    a owl:Class ;
    rdfs:comment "This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype." ;
    rdfs:label "obsolete no hermaphrodite variantity scored" ;
    owl:deprecated true .

obo:WBPhenotype_0000590
    obo:IAO_0000115 "Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage." ;
    oboInOwl:hasNarrowSynonym "cell corpse number abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000590" ;
    a owl:Class ;
    rdfs:label "cell corpse number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBPhenotype_0000591
    obo:IAO_0000115 "Animals exhibit variations in their response to a specific metal compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "metal response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000591" ;
    a owl:Class ;
    rdfs:label "metal response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_33521
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000592
    obo:IAO_0000115 "Animals exhibit variations in their response to copper compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "copper response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000592" ;
    a owl:Class ;
    rdfs:label "copper response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_30052
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000593
    obo:IAO_0000115 "Animals respond to copper at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000593" ;
    a owl:Class ;
    rdfs:label "copper hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000592 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_28694
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000594
    obo:IAO_0000115 "Any variation in the orderly movement of a cell from one site to another." ;
    oboInOwl:hasBroadSynonym "Mig" ;
    oboInOwl:hasNarrowSynonym "cell migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "migration of cells abnormal" ;
    oboInOwl:id "WBPhenotype:0000594" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016477
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000595
    obo:IAO_0000115 "Variations in the specific actions or reactions of the head in response to external or internal stimuli compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "head behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000595" ;
    a owl:Class ;
    rdfs:label "head behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000580 .

obo:WBPhenotype_0000596
    obo:IAO_0000115 "Activity characteristic of the body is altered compared to control." ;
    oboInOwl:hasNarrowSynonym "body behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000596" ;
    a owl:Class ;
    rdfs:label "body behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000580 .

obo:WBPhenotype_0000597
    obo:IAO_0000115 "Variations in the specific actions or reactions of the tail in response to external or internal stimuli compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "tail behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000597" ;
    a owl:Class ;
    rdfs:label "tail behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000580 .

obo:WBPhenotype_0000598
    obo:IAO_0000115 "Variations in the form, structure or composition of the series of related tissues lying within the body cavity and devoted to feeding and digestion compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "alimentary system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000598" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "alimentary system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000534 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005748
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000599
    obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the coelomic system, compared to control. The coelom is the fluid compartment that is in contact with internal organ." ;
    oboInOwl:hasNarrowSynonym "coelomic system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000599" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "coelomic system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000534 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005749
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000600
    obo:IAO_0000115 "Variations in the form, composition or structure of the epithelial system that serves to protect the organism from the external environment compared to control." ;
    oboInOwl:hasNarrowSynonym "epithelial system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000600" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "epithelial system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000534 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005730
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000601
    obo:IAO_0000115 "Variations in the form, structure or composition of related tissues that allow the animal to secrete saline fluid and maintain a proper salt balance compared to control. In C. elegans, four cell types (1 pore cell, 1 duct cell, 1 canal cell and a fused pair of gland cells) make up the excretory system (Wormatlas)." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000602" ;
    oboInOwl:hasExactSynonym "excretory system morphology variant" ;
    oboInOwl:hasNarrowSynonym "excretory secretory system morphology abnormal", "excretory system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000601" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "excretory secretory system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000534 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005736
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000602
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000601 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000602" ;
    a owl:Class ;
    rdfs:label "obsolete excretory system morphology abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000603
    obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work." ;
    oboInOwl:hasNarrowSynonym "muscle system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000603" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "muscle system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000534 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005737
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000604
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals." ;
    oboInOwl:hasNarrowSynonym "nervous system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "neuroanatomical defective" ;
    oboInOwl:id "WBPhenotype:0000604" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:comment "WB:WBbt:0005735." ;
    rdfs:label "nervous system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000534 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005735
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000605
    obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ;
    oboInOwl:hasNarrowSynonym "reproductive system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000605" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "reproductive system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000534 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005747
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000606
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the alimentary system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "alimentary system physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000606" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "alimentary system physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000575 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005748
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000607
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the coelomic system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "coelomic system physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000607" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "coelomic system physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000575 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005749
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000608
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the epithelial system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "epithelial system physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000608" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "epithelial system physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000575 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005730
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000609
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the excretory/secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "excretory secretory system physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000609" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "excretory secretory system physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000575 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006850
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000610
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "excretory system physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000610" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "excretory system physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000575 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005736
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000611
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "muscle system physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000611" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "muscle system physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000575 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005737
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000612
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "nervous system physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000612" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "nervous system physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000575 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005735
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000613
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the reproductive system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "reproductive system physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000613" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "reproductive system physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000575 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005747
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000614
    obo:IAO_0000115 "Any variation in the progression of the GLR accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "GLR development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000614" ;
    a owl:Class ;
    rdfs:label "GLR development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000942 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005176
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000615
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside." ;
    oboInOwl:hasNarrowSynonym "cilia morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "defective dye filling of cilia" ;
    oboInOwl:id "WBPhenotype:0000615" ;
    a owl:Class ;
    rdfs:label "cilia morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001526 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005929
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000616
    obo:IAO_0000115 "Animals display variations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly opposite the post-synaptic target and separated by a synaptic cleft." ;
    oboInOwl:hasNarrowSynonym "synapse morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000616" ;
    a owl:Class ;
    rdfs:label "synapse morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000604 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0045202
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000617
    obo:IAO_0000115 "Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products." ;
    oboInOwl:hasNarrowSynonym "alimentary system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000617" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "alimentary system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005748
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000618
    obo:IAO_0000115 "Any variation in the progression of the coelomic system over time, from its formation to its mature state compared to control." ;
    oboInOwl:hasNarrowSynonym "coelomic system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000618" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "coelomic system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005749
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000619
    obo:IAO_0000115 "Any variation in the progression of the epithelial system over time, from its formation to its mature state compared to control." ;
    oboInOwl:hasNarrowSynonym "epithelial system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000619" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "epithelial system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005730
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000620
    obo:IAO_0000115 "Any variation in the progression of the excretory secretory system over time, from its formation to its mature state compared to control. The excretory secretory system consists of the excretory system and its associated glands." ;
    oboInOwl:hasNarrowSynonym "excretory secretory system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000620" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "excretory secretory system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006850
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000621
    obo:IAO_0000115 "Variations in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste. In C. elegans, the excretory system is comprised of the excretory cell, excretory duct cell and excretory socket cell." ;
    oboInOwl:hasNarrowSynonym "excretory system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000621" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "excretory system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000620 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005736
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000622
    obo:IAO_0000115 "Any variation in the progression of the muscle system over time, from its formation to its mature state compared to control." ;
    oboInOwl:hasNarrowSynonym "muscle system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000622" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "muscle system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005737
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000623
    obo:IAO_0000115 "Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control." ;
    oboInOwl:hasNarrowSynonym "nervous system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000623" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "nervous system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007399
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000624
    obo:IAO_0000115 "Any variation in the progression of the reproductive system over time, from its formation to its mature state compared to control." ;
    oboInOwl:hasNarrowSynonym "reproductive system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "reproductive defect" ;
    oboInOwl:id "WBPhenotype:0000624" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "reproductive system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005747
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000625
    obo:IAO_0000115 "Any variation in the biosynthesis of a synapse compared to control." ;
    oboInOwl:hasExactSynonym "synapse development variant" ;
    oboInOwl:hasNarrowSynonym "synaptogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000625" ;
    a owl:Class ;
    rdfs:label "synaptogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000623 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007416
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000626
    obo:IAO_0000115 "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control." ;
    oboInOwl:hasNarrowSynonym "habituation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "non associative learning variant" ;
    oboInOwl:id "WBPhenotype:0000626" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "habituation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525, obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0046959
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000627
    obo:IAO_0000115 "Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals." ;
    oboInOwl:hasExactSynonym "anaesthetic response variant" ;
    oboInOwl:hasNarrowSynonym "anesthetic response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000627" ;
    a owl:Class ;
    rdfs:label "anesthetic response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0072347
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000628
    obo:IAO_0000115 "Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000628" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "spindle assembly defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001102, obo:WBPhenotype_0002415 .

obo:WBPhenotype_0000629
    obo:IAO_0000115 "Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000629" ;
    a owl:Class ;
    rdfs:label "excess neurite outgrowth" ;
    rdfs:subClassOf obo:WBPhenotype_0000572 .

obo:WBPhenotype_0000630
    obo:IAO_0000115 "Failure to execute the characteristic response to the bitter tastant quinine, as defined by control animals. In C. elegans, quinine is typically repellent." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000630" ;
    a owl:Class ;
    rdfs:label "quinine chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001449, obo:WBPhenotype_0001454 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050919
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_15854
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000631
    obo:IAO_0000115 "Any variation in the characteristic response(s) to drug(s) as defined by control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "drug response abnormal" ;
    oboInOwl:id "WBPhenotype:0000631" ;
    a owl:Class ;
    rdfs:label "drug response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000523 .

obo:WBPhenotype_0000632
    obo:IAO_0000115 "The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised." ;
    oboInOwl:hasNarrowSynonym "axon fasciculation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000632" ;
    a owl:Class ;
    rdfs:label "axon fasciculation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000880 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007413
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000633
    obo:IAO_0000115 "Animals display variations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "axon branching abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000633" ;
    a owl:Class ;
    rdfs:label "axon branching variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000180, obo:WBPhenotype_0001224 .

obo:WBPhenotype_0000634
    obo:IAO_0000115 "Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to control." ;
    oboInOwl:hasNarrowSynonym "pharyngeal pumping abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000634" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "pharyngeal pumping variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002056 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043050
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000635
    obo:IAO_0000115 "Any variation in the directed movement of an animal in response to chemical attractants as defined by control animals." ;
    oboInOwl:hasNarrowSynonym "positive chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000635" ;
    a owl:Class ;
    rdfs:label "positive chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001434 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000636
    obo:IAO_0000115 "Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals." ;
    oboInOwl:hasNarrowSynonym "neuron degeneration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000636" ;
    a owl:Class ;
    rdfs:label "neuron degeneration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000612 .

obo:WBPhenotype_0000637
    obo:IAO_0000115 "Characteristic entry into the dauer stage is altered compared to control animals." ;
    oboInOwl:hasBroadSynonym "Daf" ;
    oboInOwl:hasNarrowSynonym "dauer formation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000637" ;
    a owl:Class ;
    rdfs:label "dauer formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000308 .

obo:WBPhenotype_0000638
    obo:IAO_0000115 "Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage." ;
    oboInOwl:hasBroadSynonym "Mlt", "Mult" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000638" ;
    a owl:Class ;
    rdfs:label "molt defect" ;
    rdfs:subClassOf obo:WBPhenotype_0002041 .

obo:WBPhenotype_0000639
    obo:IAO_0000115 "Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C." ;
    oboInOwl:hasNarrowSynonym "temperature induced dauer formation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Hid" ;
    oboInOwl:id "WBPhenotype:0000639" ;
    a owl:Class ;
    rdfs:label "temperature induced dauer formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000146, obo:WBPhenotype_0001539 .

obo:WBPhenotype_0000640
    obo:IAO_0000115 "Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control." ;
    oboInOwl:hasBroadSynonym "Egl" ;
    oboInOwl:hasNarrowSynonym "egg laying abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "oviposition abnormal" ;
    oboInOwl:id "WBPhenotype:0000640" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:comment "Visual inspection." ;
    rdfs:label "egg laying variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000641
    obo:IAO_0000115 "Any variation in the degree of movement compared to control animals." ;
    oboInOwl:hasNarrowSynonym "activity level abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000641" ;
    a owl:Class ;
    rdfs:label "activity level variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000643 .

obo:WBPhenotype_0000642
    obo:IAO_0000115 "Worms move forward or backward with an increased rate of body bends per minute compared to control animals." ;
    oboInOwl:hasBroadSynonym "Hya" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000642" ;
    a owl:Class ;
    rdfs:label "hyperactive" ;
    rdfs:subClassOf obo:WBPhenotype_0000641 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040011
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000643
    obo:IAO_0000115 "Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals." ;
    oboInOwl:hasBroadSynonym "Unc" ;
    oboInOwl:hasNarrowSynonym "locomotion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "movement defect", "uncoordinated" ;
    oboInOwl:id "WBPhenotype:0000643" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "locomotion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001206 .

obo:WBPhenotype_0000644
    obo:IAO_0000115 "Animals do not move and are not responsive to external mechanical stimulation." ;
    oboInOwl:hasBroadSynonym "Prl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Prz" ;
    oboInOwl:id "WBPhenotype:0000644" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "paralyzed" ;
    rdfs:subClassOf obo:WBPhenotype_0001213 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000763
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000645
    obo:IAO_0000115 "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar." ;
    oboInOwl:hasBroadSynonym "Rol" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000645" ;
    a owl:Class ;
    rdfs:label "roller" ;
    rdfs:subClassOf obo:WBPhenotype_0004017 .

obo:WBPhenotype_0000646
    obo:IAO_0000115 "Animals move more slowly compared with control animals." ;
    oboInOwl:hasBroadSynonym "Slu" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lethargic", "slow" ;
    oboInOwl:id "WBPhenotype:0000646" ;
    a owl:Class ;
    rdfs:label "sluggish" ;
    rdfs:subClassOf obo:WBPhenotype_0001213 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040011
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000647
    obo:IAO_0000115 "Animals exhibit variations in any processes that lead to the successful transfer of sperm from one organism to another." ;
    oboInOwl:hasNarrowSynonym "copulation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000647" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "copulation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007620
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000648
    obo:IAO_0000115 "Any variation in the specific actions or reactions of the male that are associated with reproduction compared to control." ;
    oboInOwl:hasBroadSynonym "Cod" ;
    oboInOwl:hasNarrowSynonym "male mating abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000648" ;
    a owl:Class ;
    rdfs:label "male mating variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000647, obo:WBPhenotype_0000888 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060179
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000649
    obo:IAO_0000115 "Any variation in the male's ability to locate his partner's vulva when backing along the ventral side of the partner during mating compared to control. In C. elegans the male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." ;
    oboInOwl:hasNarrowSynonym "vulva location abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Lov" ;
    oboInOwl:id "WBPhenotype:0000649" ;
    a owl:Class ;
    rdfs:label "vulva location variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004006 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0034608
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000650
    obo:IAO_0000115 "Animals exhibit variations in the processes involved in eliminating gut contents compared to control animals. In C. elegans the sequence of events during defecation includes posterior body contraction (pBoc), relaxation, anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp), and intercycle period (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "defecation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000650" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "defecation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030421
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000651
    obo:IAO_0000115 "Animals exhibit delayed or infrequent passage and/or expulsion of fecal matter." ;
    oboInOwl:hasBroadSynonym "Con" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000651" ;
    a owl:Class ;
    rdfs:label "constipated" ;
    rdfs:subClassOf obo:WBPhenotype_0000650 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000502
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030421
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000652
    obo:IAO_0000115 "Variations in the progression of a set of interacting or interdependent entities forming the sensory system over time from an initial condition to a later condition compared to control animals. The sensory system is involved in the perception of a stimuli, its conversion into a signal and the recognition and characterization of the resulting signal." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000248" ;
    oboInOwl:hasNarrowSynonym "sensory system abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000652" ;
    a owl:Class ;
    rdfs:label "sensory system variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000612 .

obo:WBPhenotype_0000653
    obo:IAO_0000115 "Variations in the progression of a set of interacting or interdependent entities forming the mechanosensory system over time from an initial condition to a later condition compared to control animals. The mechanosensory system is involved in the perception of a mechanical stimuli, its conversion into a signal and the recognition and characterization of the resulting signal." ;
    oboInOwl:hasNarrowSynonym "mechanosensory system abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000653" ;
    a owl:Class ;
    rdfs:label "mechanosensory system variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000652 .

obo:WBPhenotype_0000654
    obo:IAO_0000115 "Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control." ;
    oboInOwl:hasNarrowSynonym "synaptic vesicle exocytosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000654" ;
    a owl:Class ;
    rdfs:label "synaptic vesicle exocytosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000728, obo:WBPhenotype_0001684 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016079
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000655
    obo:IAO_0000115 "Animals exhibit variations in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control." ;
    oboInOwl:hasNarrowSynonym "GABA synaptic transmission abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000655" ;
    a owl:Class ;
    rdfs:label "GABA synaptic transmission variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000584 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051932
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000656
    obo:IAO_0000115 "Animals exhibit variations in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control." ;
    oboInOwl:hasNarrowSynonym "acetylcholine synaptic transmission abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000656" ;
    a owl:Class ;
    rdfs:label "acetylcholine synaptic transmission variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000584 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007271
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000657
    obo:IAO_0000115 "Any variation in the process of information transfer between two neurons; usually in reference to chemical synapses, but can also be used to refer to electrical synapses compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "neuronal synaptic transmission abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000657" ;
    a owl:Class ;
    rdfs:label "neuronal synaptic transmission variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000584 .

obo:WBPhenotype_0000658
    obo:IAO_0000115 "Any variation in the process of communication across a synapse between a neuron and a target muscle cell compared to control animals." ;
    oboInOwl:hasNarrowSynonym "neuromuscular synaptic transmission abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000658" ;
    a owl:Class ;
    rdfs:label "neuromuscular synaptic transmission variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000584 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007274
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000659
    obo:IAO_0000115 "Behavior associated with the intake of food is altered compared to control." ;
    oboInOwl:hasNarrowSynonym "feeding behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000659" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "feeding behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007631
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000660
    obo:IAO_0000115 "Worms are found in clumps and/or crowded at the border of the bacterial lawn more frequently than control animals. This behavior is not due to mobility defects." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "bordering increased", "social behavior enhanced" ;
    oboInOwl:id "WBPhenotype:0000660" ;
    a owl:Class ;
    rdfs:label "social feeding increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000659, obo:WBPhenotype_0001291 .

obo:WBPhenotype_0000661
    obo:IAO_0000115 "Animals disperse across a bacterial lawn and feed alone. When food is limiting, they can aggregate into swarms or clumps, but disperse once again when food is absent." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "solitary behavior enhanced", "solitary forager on food" ;
    oboInOwl:id "WBPhenotype:0000661" ;
    a owl:Class ;
    rdfs:label "solitary feeding increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000659, obo:WBPhenotype_0001291 .

obo:WBPhenotype_0000662
    obo:IAO_0000115 "Variations in the behavior by which an organism locates food compared to control animals. In C. elegans roaming or dwelling activity on food are two examples of parameters used to assess this behavior. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region." ;
    oboInOwl:hasBroadSynonym "Fab" ;
    oboInOwl:hasNarrowSynonym "foraging behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000662" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "foraging behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060756
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000663
    obo:IAO_0000115 "Animals exhibit variations in the avoidance response to solutions of a particular osmotic strength compared to control. In C. elegans, animals typically avoid solutions of high osmotic strength." ;
    oboInOwl:hasNarrowSynonym "osmotic avoidance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Osm" ;
    oboInOwl:id "WBPhenotype:0000663" ;
    a owl:Class ;
    rdfs:label "osmotic avoidance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000481 .

obo:WBPhenotype_0000664
    obo:IAO_0000115 "The maximum ventral and dorsal flex of the animal is greater than that observed for control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0004021" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "loopy" ;
    oboInOwl:id "WBPhenotype:0000664" ;
    a owl:Class ;
    rdfs:label "exaggerated body bends" ;
    rdfs:subClassOf obo:WBPhenotype_0001703 .

obo:WBPhenotype_0000665
    obo:IAO_0000115 "Any variation that disrupts the connectivity between the somatic gonad and the adjoining tissues compared to control. In C. elegans this connnection is between the somatic gonad and the vulva in hermaphrodites and between the somatic gonad and proctodeum in males." ;
    oboInOwl:hasNarrowSynonym "connection of gonad abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Cog" ;
    oboInOwl:id "WBPhenotype:0000665" ;
    a owl:Class ;
    rdfs:label "connection of gonad variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000605 .

obo:WBPhenotype_0000666
    obo:IAO_0000115 "Any variation that disrupts the release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control." ;
    oboInOwl:hasNarrowSynonym "ovulation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000666" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "ovulation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030728
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000667
    obo:IAO_0000115 "The specialized tissue of the reproductive tract that produces gamete is shifted from its customary place as defined by control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ectopic gonad" ;
    oboInOwl:id "WBPhenotype:0000667" ;
    a owl:Class ;
    rdfs:label "gonad displaced" ;
    rdfs:subClassOf obo:WBPhenotype_0000977 .

obo:WBPhenotype_0000668
    obo:IAO_0000115 "Any variation that results in the presence of mature oocytes with distended polyploid nuclei. In C. elegans, such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized." ;
    oboInOwl:hasBroadSynonym "Emo" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "arrest in meiosis I" ;
    oboInOwl:id "WBPhenotype:0000668" ;
    a owl:Class ;
    rdfs:label "endomitotic oocytes" ;
    rdfs:subClassOf obo:WBPhenotype_0001260 .

obo:WBPhenotype_0000669
    obo:IAO_0000115 "Variations in the progression of the muscles of the adult reproductive system over time form their initial formation to their mature structure compared to control." ;
    oboInOwl:hasNarrowSynonym "sex muscle development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000669" ;
    a owl:Class ;
    rdfs:label "sex muscle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000624, obo:WBPhenotype_0000860 .

obo:WBPhenotype_0000670
    obo:IAO_0000115 "Any variation in the processes that influence the generation and maturation of spermatozoa (motile sperm) compared to control." ;
    oboInOwl:hasBroadSynonym "Spe" ;
    oboInOwl:hasExactSynonym "spermatocyte germ cell differentiation abnormal" ;
    oboInOwl:hasNarrowSynonym "spermatogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000670" ;
    a owl:Class ;
    rdfs:label "spermatogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000894 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007283
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000671
    obo:IAO_0000115 "Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to copper to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000671" ;
    a owl:Class ;
    rdfs:label "resistant to copper" ;
    rdfs:subClassOf obo:WBPhenotype_0000592 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_28694
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000672
    obo:IAO_0000115 "Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "presynaptic vesicle cluster localization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "synaptic vesicle cluster localization abnormal" ;
    oboInOwl:id "WBPhenotype:0000672" ;
    a owl:Class ;
    rdfs:label "presynaptic vesicle cluster localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000102 .

obo:WBPhenotype_0000673
    obo:IAO_0000115 "The number of offspring produced is altered compared to that of control animals." ;
    oboInOwl:hasNarrowSynonym "brood size abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000673" ;
    a owl:Class ;
    rdfs:label "brood size variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000806 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000276
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000674
    obo:IAO_0000115 "The developmental progression of an animal, from its formation to its mature structure occurs over a longer time period compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "retarded development" ;
    oboInOwl:id "WBPhenotype:0000674" ;
    a owl:Class ;
    rdfs:label "slow development" ;
    rdfs:subClassOf obo:WBPhenotype_0000438 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0032502
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000675
    obo:IAO_0000115 "Animals die after fusion of gametes without dividing." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Emb" ;
    oboInOwl:id "WBPhenotype:0000675" ;
    a owl:Class ;
    rdfs:label "zygotic lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000213 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CL_0000365
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000676
    obo:IAO_0000115 "The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "growth rate abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000676" ;
    a owl:Class ;
    rdfs:label "growth rate variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000030 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001492
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000677
    obo:IAO_0000115 "Animals fail to receive, process or recognize a sensory chemical stimulus in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000677" ;
    a owl:Class ;
    rdfs:label "chemosensation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001050 .

obo:WBPhenotype_0000678
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000678" ;
    a owl:Class ;
    rdfs:comment "This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype." ;
    rdfs:label "obsolete no copper sensitivity" ;
    owl:deprecated true .

obo:WBPhenotype_0000679
    obo:IAO_0000115 "Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals." ;
    oboInOwl:hasNarrowSynonym "transgene subcellular localization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000679" ;
    a owl:Class ;
    rdfs:label "transgene subcellular localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000961 .

obo:WBPhenotype_0000680
    obo:IAO_0000115 "Animals exhibit variations in their response to aldicarb compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "aldicarb response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000680" ;
    a owl:Class ;
    rdfs:label "aldicarb response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001290 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_2555
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000681
    obo:IAO_0000115 "Animals exhibit variations in their response to DMPP compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "DMPP response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000681" ;
    a owl:Class ;
    rdfs:label "DMPP response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0000682
    obo:IAO_0000115 "Hermaphrodites are transformed into fertile females; In C. elegans, XO fog animals are somatically male but produce oocytes instead of, or in addition to, sperm." ;
    oboInOwl:hasBroadSynonym "Fog" ;
    oboInOwl:hasExactSynonym "feminization of germ line" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000682" ;
    a owl:Class ;
    rdfs:label "feminization of germline" ;
    rdfs:subClassOf obo:WBPhenotype_0000687, obo:WBPhenotype_0000812 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000467
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040022
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000683
    obo:IAO_0000115 "The germ line is sexually transformed from hermaphrodite to male. In C. elegans, XX mog animals are somatically hermaphrodite, but germ cells that normally would become oocytes are transformed into sperm." ;
    oboInOwl:hasBroadSynonym "Mog" ;
    oboInOwl:hasExactSynonym "masculinization of germ line" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000683" ;
    a owl:Class ;
    rdfs:label "masculinization of germline" ;
    rdfs:subClassOf obo:WBPhenotype_0000812, obo:WBPhenotype_0001572 .

obo:WBPhenotype_0000684
    obo:IAO_0000115 "Germ cell populations are reduced compared to control animals." ;
    oboInOwl:hasBroadSynonym "Fgc" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "germline underproliferation" ;
    oboInOwl:id "WBPhenotype:0000684" ;
    a owl:Class ;
    rdfs:label "fewer germ cells" ;
    rdfs:subClassOf obo:WBPhenotype_0000823, obo:WBPhenotype_0002174 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006796
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000685
    obo:IAO_0000115 "Any variation that causes a reduction in growth rate during larval stages compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000685" ;
    a owl:Class ;
    rdfs:label "larval growth slow" ;
    rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0000676, obo:WBPhenotype_0001016 .

obo:WBPhenotype_0000686
    obo:IAO_0000115 "Animals exhibit variations in their response ionizing radiation compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism ionizing radiation response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000686" ;
    a owl:Class ;
    rdfs:label "organism ionizing radiation response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010212
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000687
    obo:IAO_0000115 "Both hermaphrodites and males develop into fertile females." ;
    oboInOwl:hasBroadSynonym "Fem" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000687" ;
    a owl:Class ;
    rdfs:label "feminization of XX and XO animals" ;
    rdfs:subClassOf obo:WBPhenotype_0000049, obo:WBPhenotype_0000624, obo:WBPhenotype_0000822 .

obo:WBPhenotype_0000688
    obo:IAO_0000115 "Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce." ;
    oboInOwl:hasBroadSynonym "Ste" ;
    oboInOwl:hasExactSynonym "semi sterile" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000688" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "sterile" ;
    rdfs:subClassOf obo:WBPhenotype_0001384 .

obo:WBPhenotype_0000689
    obo:IAO_0000115 "Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." ;
    oboInOwl:hasBroadSynonym "Ste" ;
    oboInOwl:hasExactSynonym "Reduced fecundity of injected worm" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "sterile F0 fertility problems" ;
    oboInOwl:id "WBPhenotype:0000689" ;
    a owl:Class ;
    rdfs:label "maternal sterile" ;
    rdfs:subClassOf obo:WBPhenotype_0000694 .

obo:WBPhenotype_0000690
    obo:IAO_0000115 "Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas)." ;
    oboInOwl:hasBroadSynonym "Gom" ;
    oboInOwl:hasNarrowSynonym "gonad migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000690" ;
    a owl:Class ;
    rdfs:label "gonad migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000624 .

obo:WBPhenotype_0000691
    obo:IAO_0000115 "Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control." ;
    oboInOwl:hasNarrowSynonym "gonad development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Gon", "gonadogenesis abnormal" ;
    oboInOwl:id "WBPhenotype:0000691" ;
    a owl:Class ;
    rdfs:label "gonad development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000624 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008406
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000692
    obo:IAO_0000115 "X0 animals fail to generate viable cross-progeny." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000692" ;
    a owl:Class ;
    rdfs:label "male sterile" ;
    rdfs:subClassOf obo:WBPhenotype_0000688, obo:WBPhenotype_0000863 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000956
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000056
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000693
    obo:IAO_0000115 "Any perturbation that renders male derived sperm ineffective at fertilizing an oocyte." ;
    oboInOwl:hasBroadSynonym "Fer" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000693" ;
    a owl:Class ;
    rdfs:label "male sperm fertilization defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000692 .

obo:WBPhenotype_0000694
    obo:IAO_0000115 "Hermaphrodites fail to generate viable self-progeny and/or cross-progeny." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000694" ;
    a owl:Class ;
    rdfs:label "hermaphrodite sterile" ;
    rdfs:subClassOf obo:WBPhenotype_0000688, obo:WBPhenotype_0001259 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000956
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007849
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000695
    obo:IAO_0000115 "Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control." ;
    oboInOwl:hasNarrowSynonym "vulva morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000695" ;
    a owl:Class ;
    rdfs:label "vulva morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001335 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006748
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000696
    obo:IAO_0000115 "The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva)." ;
    oboInOwl:hasBroadSynonym "Evl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000696" ;
    a owl:Class ;
    rdfs:label "everted vulva" ;
    rdfs:subClassOf obo:WBPhenotype_0000695 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001597
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006748
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000697
    obo:IAO_0000115 "Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva." ;
    oboInOwl:hasBroadSynonym "Pvl", "Pvu" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000697" ;
    a owl:Class ;
    rdfs:label "protruding vulva" ;
    rdfs:subClassOf obo:WBPhenotype_0000695 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001598
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006748
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000698
    obo:IAO_0000115 "No vulval tissue is produced. In C. elegans, this is usually a result of all six vulval precursor cells adopting a tertiary fate." ;
    oboInOwl:hasBroadSynonym "Vul" ;
    oboInOwl:hasExactSynonym "underinduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000698" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "vulvaless" ;
    rdfs:subClassOf obo:WBPhenotype_0000219 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006748
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000699
    obo:IAO_0000115 "Variations in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure compared to control. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ;
    oboInOwl:hasNarrowSynonym "vulva development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000699" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "vulva development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000624 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040025
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000700
    obo:IAO_0000115 "Multiple vulva-like protrusions are present along the ventral side of the animal. In C. elegans, this is usually a result of all six vulval precursor cells adopting primary or secondary vulval fates." ;
    oboInOwl:hasBroadSynonym "Muv" ;
    oboInOwl:hasExactSynonym "overinduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000700" ;
    a owl:Class ;
    rdfs:label "multivulva" ;
    rdfs:subClassOf obo:WBPhenotype_0000218 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006748
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000701
    obo:IAO_0000115 "Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation." ;
    oboInOwl:hasNarrowSynonym "epithelial development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "epidermal morphogenesis variant" ;
    oboInOwl:id "WBPhenotype:0000701" ;
    a owl:Class ;
    rdfs:label "epithelial development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000619 .

obo:WBPhenotype_0000702
    obo:IAO_0000115 "Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development." ;
    oboInOwl:hasDbXref "PMID:15341747" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000702" ;
    a owl:Class ;
    rdfs:label "epithelial cell fusion failure" ;
    rdfs:subClassOf obo:WBPhenotype_0000165, obo:WBPhenotype_0000701 .

obo:WBPhenotype_0000703
    obo:IAO_0000115 "Variations in the form, composition or structure of the layer of cells that cover the external surface of an organism and form the inner lining between the tissues and organs of that organism and the external environment compared to control. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "epithelial morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "hypodermal morphology abnormal" ;
    oboInOwl:id "WBPhenotype:0000703" ;
    a owl:Class ;
    rdfs:label "epithelial morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000600 .

obo:WBPhenotype_0000704
    obo:IAO_0000115 "Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "excretory canal morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000704" ;
    a owl:Class ;
    rdfs:label "excretory canal morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000916 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005775
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000705
    obo:IAO_0000115 "Any variation in the progression of an intestinal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "intestinal cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000705" ;
    a owl:Class ;
    rdfs:label "intestinal cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000708 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005792
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000706
    obo:IAO_0000115 "Animals lack birefringent containing compartments in embryonic intestinal cells; however, these compartments appear in adult stages." ;
    oboInOwl:hasBroadSynonym "Glo" ;
    oboInOwl:hasDbXref "PMID:15843430" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "gut granule loss" ;
    oboInOwl:id "WBPhenotype:0000706" ;
    a owl:Class ;
    rdfs:label "gut granule biogenesis reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000103, obo:WBPhenotype_0001430 .

obo:WBPhenotype_0000707
    obo:IAO_0000115 "Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb)." ;
    oboInOwl:hasNarrowSynonym "pharyngeal development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000707" ;
    a owl:Class ;
    rdfs:label "pharyngeal development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000617 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060465
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000708
    obo:IAO_0000115 "Variations in the progression of the intestine over time from its initial formation to its mature structure compared to control." ;
    oboInOwl:hasNarrowSynonym "intestinal development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "endoderm development abnormal", "gut development abnormal" ;
    oboInOwl:id "WBPhenotype:0000708" ;
    a owl:Class ;
    rdfs:label "intestinal development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000617 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048565
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000709
    obo:IAO_0000115 "Variations in the form or composition of the mouthparts at the anterior end of the digestive tract which contain a series of radial muscles, related neurons and epithelial cells, and several gland cells which may aid in digestion compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "pharyngeal morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000709" ;
    a owl:Class ;
    rdfs:label "pharyngeal morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000598 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003681
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000710
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "intestinal morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000710" ;
    a owl:Class ;
    rdfs:label "intestinal morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000598 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005772
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000711
    obo:IAO_0000115 "Animals exhibit increased sensitivity to the effects of ion producing radiation compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000711" ;
    a owl:Class ;
    rdfs:label "organism hypersensitive ionizing radiation" ;
    rdfs:subClassOf obo:WBPhenotype_0000686 .

obo:WBPhenotype_0000712
    obo:IAO_0000115 "Germ cells exhibit variations in their response to ionizing radiation compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "germ cell ionizing radiation response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000712" ;
    a owl:Class ;
    rdfs:label "germ cell ionizing radiation response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000987 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0071479
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006796
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000713
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000981 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000713" ;
    a owl:Class ;
    rdfs:label "obsolete spermatocyte division abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000714
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000553 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000714" ;
    a owl:Class ;
    rdfs:label "obsolete disorganized muscle" ;
    owl:deprecated true .

obo:WBPhenotype_0000715
    obo:IAO_0000115 "Animals exhibit a greater number of embryonic muscle cells compared to control." ;
    oboInOwl:hasBroadSynonym "Mex" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000715" ;
    a owl:Class ;
    rdfs:label "muscle excess" ;
    rdfs:subClassOf obo:WBPhenotype_0000622, obo:WBPhenotype_0002175 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003675
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000716
    obo:IAO_0000115 "Any variation in the connection of a cell whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control." ;
    oboInOwl:hasNarrowSynonym "muscle cell attachment abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000716" ;
    a owl:Class ;
    rdfs:label "muscle cell attachment variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000990 .

obo:WBPhenotype_0000717
    obo:IAO_0000115 "Variations in the processes that convert a gene's sequence into a mature gene product or products (proteins or RNA), compared to control." ;
    oboInOwl:hasNarrowSynonym "gene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000717" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "gene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010467
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000718
    obo:IAO_0000115 "Variations in the process of normalizing the expression level of X-linked genes between XX and XO animals compared to control." ;
    oboInOwl:hasNarrowSynonym "dosage compensation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000718" ;
    a owl:Class ;
    rdfs:comment "Possible XP GO:0007549." ;
    rdfs:label "dosage compensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000717 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007549
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000719
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0000306, obo:WBPhenotype_0000717 ;
    oboInOwl:hasNarrowSynonym "reporter gene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000719" ;
    a owl:Class ;
    rdfs:label "obsolete reporter gene expression variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000720
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0000111, obo:WBPhenotype_0000961 ;
    oboInOwl:hasNarrowSynonym "pattern of reporter gene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000720" ;
    a owl:Class ;
    rdfs:label "obsolete pattern of reporter gene expression variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000721
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0000962 ;
    oboInOwl:hasExactSynonym "level of reporter gene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000721" ;
    a owl:Class ;
    rdfs:label "obsolete level of reporter gene expression variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000722
    obo:IAO_0000115 "Animals exhibit variations in the appearance of nucleoli compared to control animals." ;
    oboInOwl:hasNarrowSynonym "nucleolus abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000722" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "nucleolus variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001028 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005730
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000723
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000258 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000723" ;
    a owl:Class ;
    rdfs:label "obsolete cellular secretion abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000724
    obo:IAO_0000115 "Variations in the regulated release of proteins from a cell or group of cells compared to control." ;
    oboInOwl:hasNarrowSynonym "protein secretion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000724" ;
    a owl:Class ;
    rdfs:label "protein secretion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000258 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009306
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000725
    obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of lipid within the organism or cell compared to control." ;
    oboInOwl:hasNarrowSynonym "lipid metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000725" ;
    a owl:Class ;
    rdfs:label "lipid metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006629
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000726
    obo:IAO_0000115 "Any variation of the specific binding of a molecule to its partner, which typically results in a change in cell activity, compared to control." ;
    oboInOwl:hasNarrowSynonym "ligand binding abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000726" ;
    a owl:Class ;
    rdfs:label "ligand binding variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000727 .

obo:WBPhenotype_0000727
    obo:IAO_0000115 "Any variation in the function of naturally occurring macromolecular substances known as enzymes compared to control. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ;
    oboInOwl:hasNarrowSynonym "enzyme activity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000727" ;
    a owl:Class ;
    rdfs:label "enzyme activity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0003824
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000728
    obo:IAO_0000115 "Variations in the process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, compared to control." ;
    oboInOwl:hasNarrowSynonym "exocytosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000728" ;
    a owl:Class ;
    rdfs:label "exocytosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000258 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006887
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000729
    obo:IAO_0000115 "Animals exhibit variations in any of the processes that lead to the termination of vital functions of a cell." ;
    oboInOwl:hasBroadSynonym "Ced" ;
    oboInOwl:hasNarrowSynonym "cell death abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000729" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell death variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008219
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000730
    obo:IAO_0000115 "Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell." ;
    oboInOwl:hasBroadSynonym "Ced" ;
    oboInOwl:hasNarrowSynonym "apoptosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000730" ;
    a owl:Class ;
    rdfs:label "apoptosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001172 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006915
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000731
    obo:IAO_0000115 "Germ cells exhibit increased sensitivity to the effects of ion producing radiation compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000731" ;
    a owl:Class ;
    rdfs:label "germ cell hypersensitive ionizing radiation" ;
    rdfs:subClassOf obo:WBPhenotype_0000712, obo:WBPhenotype_0001324 .

obo:WBPhenotype_0000732
    obo:IAO_0000115 "Variations in any process that involves the maintenance, biosynthesis or accumulation of DNA in the organism compared to control." ;
    oboInOwl:hasNarrowSynonym "DNA metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000732" ;
    a owl:Class ;
    rdfs:label "DNA metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000463, obo:WBPhenotype_0000585 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006259
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000733
    obo:IAO_0000115 "Any variation in the catalysis of a biochemical reaction compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ;
    oboInOwl:hasNarrowSynonym "catalysis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000733" ;
    a owl:Class ;
    rdfs:label "catalysis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000727 .

obo:WBPhenotype_0000734
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the hypodermal system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "hypodermal cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000734" ;
    a owl:Class ;
    rdfs:label "hypodermal cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000608 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0007846
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000735
    obo:IAO_0000115 "Any variation in the regulated re-replication of DNA in the hypodermal cells during a single cell cycle, compared to control." ;
    oboInOwl:hasNarrowSynonym "endoreduplication of hypodermal nuclei abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000735" ;
    a owl:Class ;
    rdfs:label "endoreduplication of hypodermal nuclei variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000734 .

obo:WBPhenotype_0000736
    obo:IAO_0000115 "Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control." ;
    oboInOwl:hasExactSynonym "autophagy abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000736" ;
    a owl:Class ;
    rdfs:label "autophagy variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000585 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006914
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000737
    obo:IAO_0000115 "Germ cells fail to respond to the dosage of ion producing radiation that elicits a response in control animals. Alternatively, germ cells require a higher dosage or a longer exposure to ion producing radiation to elicit the same response as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000737" ;
    a owl:Class ;
    rdfs:label "germ cell resistant ionizing radiation" ;
    rdfs:subClassOf obo:WBPhenotype_0000712, obo:WBPhenotype_0001324 .

obo:WBPhenotype_0000738
    obo:IAO_0000115 "The response to a change in the environment is altered compared to control." ;
    oboInOwl:hasNarrowSynonym "organism environmental stimulus response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000738" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "organism environmental stimulus response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009605
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000739
    obo:IAO_0000115 "Variations in the activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism, compared to control." ;
    oboInOwl:hasNarrowSynonym "DNA damage response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000739" ;
    a owl:Class ;
    rdfs:label "DNA damage response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142 .

obo:WBPhenotype_0000740
    obo:IAO_0000115 "Cells of the animals exhibit variations in the initiation, progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "cell cycle abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000740" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell cycle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007049
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000741
    obo:IAO_0000115 "Mitotic cells exhibit variations in the execution of cell-cycle arrest in response to DNA damage." ;
    oboInOwl:hasNarrowSynonym "DNA damage checkpoint abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000741" ;
    a owl:Class ;
    rdfs:label "DNA damage checkpoint variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000740 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000077
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000742
    obo:IAO_0000115 "Variations in the process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents, compared to control." ;
    oboInOwl:hasNarrowSynonym "DNA recombination abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000742" ;
    a owl:Class ;
    rdfs:label "DNA recombination variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000732 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006310
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000743
    obo:IAO_0000115 "Animals exhibit variations in their response to gene silencing triggered by double stranded RNA (RNAi), compared to control." ;
    oboInOwl:hasBroadSynonym "Rde" ;
    oboInOwl:hasNarrowSynonym "RNAi response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000743" ;
    a owl:Class ;
    rdfs:label "RNAi response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0016246
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000744
    obo:IAO_0000115 "Animals exhibit variations in the silencing of endogenous genes after introduction of repetitive exogenous cognate DNA compared to control." ;
    oboInOwl:hasNarrowSynonym "transgene induced cosuppression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000744" ;
    a owl:Class ;
    rdfs:label "transgene induced cosuppression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002063 .

obo:WBPhenotype_0000745
    obo:IAO_0000115 "Animals exhibit variations in the activity of endogenous transposons compared to control. In C. elegans transposon activity is often measured by the rate of reversion of mutations induced by transposon insertions." ;
    oboInOwl:hasNarrowSynonym "transposon silencing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000745" ;
    a owl:Class ;
    rdfs:label "transposon silencing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002063 .

obo:WBPhenotype_0000746
    obo:IAO_0000115 "Any variation that alters the physical partitioning and separation of a cell into daughter cells compared to control." ;
    oboInOwl:hasNarrowSynonym "cell division abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000746" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell division variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051301
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000747
    obo:IAO_0000115 "Any defects in the muscle contractions that control feeding. Contractions are necessary for bacterial uptake from the surrounding environment." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000747" ;
    a owl:Class ;
    rdfs:label "pharyngeal contraction defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000980 .

obo:WBPhenotype_0000748
    obo:IAO_0000115 "Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes)." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000748" ;
    a owl:Class ;
    rdfs:label "asymmetric cell division defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001585 .

obo:WBPhenotype_0000749
    obo:IAO_0000115 "Variations in the progression of an embryo over time, from zygote formation to hatching compared to control." ;
    oboInOwl:hasNarrowSynonym "embryonic development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "developmental defects detected in embryos" ;
    oboInOwl:id "WBPhenotype:0000749" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "embryonic development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000750
    obo:IAO_0000115 "Variations in the progression of a larva over time, from its formation to the mature structure compared to control. The larva is the early, immature form of an animal between hatching and adulthood." ;
    oboInOwl:hasNarrowSynonym "larval development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000750" ;
    a owl:Class ;
    rdfs:label "larval development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000049 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000751
    obo:IAO_0000115 "Variations in the progression of a newly hatched animal through the first larval molt compared to control." ;
    oboInOwl:hasNarrowSynonym "L1 larval development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000751" ;
    a owl:Class ;
    rdfs:label "L1 larval development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000750 .

obo:WBPhenotype_0000752
    obo:IAO_0000115 "Variations in the progression of the second larval stage compared to control." ;
    oboInOwl:hasNarrowSynonym "L2 larval development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000752" ;
    a owl:Class ;
    rdfs:label "L2 larval development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000750 .

obo:WBPhenotype_0000753
    obo:IAO_0000115 "Variations in the progression of the third larval stage compared to control." ;
    oboInOwl:hasNarrowSynonym "L3 larval development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000753" ;
    a owl:Class ;
    rdfs:label "L3 larval development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000750 .

obo:WBPhenotype_0000754
    obo:IAO_0000115 "Variations in the progression of the fourth larval stage compared to control." ;
    oboInOwl:hasNarrowSynonym "L4 larval development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000754" ;
    a owl:Class ;
    rdfs:label "L4 larval development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000750 .

obo:WBPhenotype_0000755
    obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L1 to L2 transition." ;
    oboInOwl:hasNarrowSynonym "L1 L2 molt abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "L1 molt" ;
    oboInOwl:id "WBPhenotype:0000755" ;
    a owl:Class ;
    rdfs:label "L1 L2 molt defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000638 .

obo:WBPhenotype_0000756
    obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L2 to L3 transition." ;
    oboInOwl:hasNarrowSynonym "L2 L3 molt abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "L2 molt" ;
    oboInOwl:id "WBPhenotype:0000756" ;
    a owl:Class ;
    rdfs:label "L2 L3 molt defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000638 .

obo:WBPhenotype_0000757
    obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L3 to L4 transition." ;
    oboInOwl:hasNarrowSynonym "L3 L4 molt abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "L3 molt" ;
    oboInOwl:id "WBPhenotype:0000757" ;
    a owl:Class ;
    rdfs:label "L3 L4 molt defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000638 .

obo:WBPhenotype_0000758
    obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L4 to adult transition." ;
    oboInOwl:hasNarrowSynonym "L4 adult molt abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "L4 molt" ;
    oboInOwl:id "WBPhenotype:0000758" ;
    a owl:Class ;
    rdfs:label "L4 adult molt defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000638 .

obo:WBPhenotype_0000759
    obo:IAO_0000115 "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle." ;
    oboInOwl:hasBroadSynonym "Emb", "Spd" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000759" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "spindle defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000764, obo:WBPhenotype_0001100, obo:WBPhenotype_0002414 .

obo:WBPhenotype_0000760
    obo:IAO_0000115 "The alignment of the spindle relative to other cellular structures in the cells of an embryo varies from that observed in control animals." ;
    oboInOwl:hasBroadSynonym "Emb", "Spn" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000760" ;
    a owl:Class ;
    rdfs:label "spindle orientation defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000761, obo:WBPhenotype_0001681 .

obo:WBPhenotype_0000761
    obo:IAO_0000115 "Early embryos exhibit defects in the placement or the alignment of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ;
    oboInOwl:hasBroadSynonym "Emb", "Spo" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Spi" ;
    oboInOwl:id "WBPhenotype:0000761" ;
    a owl:Class ;
    rdfs:label "spindle position orientation defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001102 .

obo:WBPhenotype_0000762
    obo:IAO_0000115 "Early embryos exhibit defects in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ;
    oboInOwl:hasBroadSynonym "Abs", "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000762" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "spindle position defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000761, obo:WBPhenotype_0002416 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000140
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0005819
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000763
    obo:IAO_0000115 "Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for an embryonic cell to carry out its normal function and activities or be able to perceive and respond to stimuli." ;
    oboInOwl:hasNarrowSynonym "embryonic cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000763" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "embryonic cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0007028
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000764
    obo:IAO_0000115 "Variations in the processes that are carried out at in the embryo which results in its formation or the arrangement of constituent parts, compared to control." ;
    oboInOwl:hasNarrowSynonym "embryonic cell organization biogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000764" ;
    a owl:Class ;
    rdfs:label "embryonic cell organization biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000749, obo:WBPhenotype_0000763, obo:WBPhenotype_0010002 .

obo:WBPhenotype_0000765
    obo:IAO_0000115 "The embryos exhibit defects in the cell cycle process whereby the distance is lengthened between poles of the spindle." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000765" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "spindle elongation integrity defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001102 .

obo:WBPhenotype_0000766
    obo:IAO_0000115 "Any variation in the rotation of the centrosome-pronuclear complex after its migration toward the center of the embryo, compared to control." ;
    oboInOwl:hasBroadSynonym "Rot" ;
    oboInOwl:hasNarrowSynonym "centrosome pair and associated pronuclear rotation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000766" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "centrosome pair and associated pronuclear rotation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000764 .

obo:WBPhenotype_0000767
    obo:IAO_0000115 "Sparse or enlarged yolk granules." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000767" ;
    a owl:Class ;
    rdfs:label "integrity of membranous organelles defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000585, obo:WBPhenotype_0001100 .

obo:WBPhenotype_0000768
    obo:IAO_0000115 "Areas devoid of yolk granules throughout the embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "cytoplasmic structure abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Aberrant Cytoplasmic Structure", "cellular structure disorganized" ;
    oboInOwl:id "WBPhenotype:0000768" ;
    a owl:Class ;
    rdfs:label "cytoplasmic structure defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001081 .

obo:WBPhenotype_0000769
    obo:IAO_0000115 "Embryos exhibit defects in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control embryos." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000769" ;
    a owl:Class ;
    rdfs:label "cytoplasmic appearance defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001427 .

obo:WBPhenotype_0000770
    obo:IAO_0000115 "Animals exhibit variations in the appearance of embryonic cells compared to control." ;
    oboInOwl:hasNarrowSynonym "embryonic cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000770" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "embryonic cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007028
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000771
    obo:IAO_0000115 "Centrosomes detach from the male pronucleus." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000771" ;
    a owl:Class ;
    rdfs:label "centrosome attachment defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000770, obo:WBPhenotype_0001100, obo:WBPhenotype_0001903 .

obo:WBPhenotype_0000772
    obo:IAO_0000115 "Daughter nuclei are deformed and stay close to central cortex, cytokinesis defects." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000772" ;
    a owl:Class ;
    rdfs:label "sister chromatid segregation defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000773, obo:WBPhenotype_0001078 .

obo:WBPhenotype_0000773
    obo:IAO_0000115 "Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control." ;
    oboInOwl:hasNarrowSynonym "chromosome segregation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000773" ;
    a owl:Class ;
    rdfs:label "chromosome segregation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000585 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007059
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000774
    obo:IAO_0000115 "Any variation in the processes that govern the generation and maintenance of gametes compared to control." ;
    oboInOwl:hasNarrowSynonym "gametogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000774" ;
    a owl:Class ;
    rdfs:label "gametogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000624 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007276
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000775
    obo:IAO_0000115 "Variations in the specialized nuclear and cytoplasmic divisions of a single diploid cell, whose specific outcome is the formation of four haploid daughter cells compared to control. Meiosis occurs during the formation of gametes." ;
    oboInOwl:hasNarrowSynonym "meiosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Mei", "germ cell meiosis abnormal", "germ cell meiosis variant" ;
    oboInOwl:id "WBPhenotype:0000775" ;
    a owl:Class ;
    rdfs:label "meiosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746, obo:WBPhenotype_0000812 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051321
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000776
    obo:IAO_0000115 "Male and female PNs not visible; embryo often fills egg shell completely." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "passage through meiosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000776" ;
    a owl:Class ;
    rdfs:label "passage through meiosis defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001041 .

obo:WBPhenotype_0000777
    obo:IAO_0000115 "Unextruded or resorbed polar body(ies) leading to an extra PNs in P0 and/or extra karyomeres in AB/P1." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "polar body extrusion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000777" ;
    a owl:Class ;
    rdfs:label "polar body extrusion defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0001147 .

obo:WBPhenotype_0000778
    obo:IAO_0000115 "Animals are unable to ingest nutrients at a rate similar to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000778" ;
    a owl:Class ;
    rdfs:label "feeding inefficient" ;
    rdfs:subClassOf obo:WBPhenotype_0000659 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001677
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007631
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000779
    obo:IAO_0000115 "Cessation of development during the final stages of embryogenesis. In C. elegans, this stage normally occurs 620-800 min after the first cleavage at 20C and is the stage after elongation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000779" ;
    a owl:Class ;
    rdfs:label "late embryonic arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000867 .

obo:WBPhenotype_0000780
    obo:IAO_0000115 "Animals rotate back and forth around their longitudinal axes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000780" ;
    a owl:Class ;
    rdfs:label "shaker" ;
    rdfs:subClassOf obo:WBPhenotype_0001701 .

obo:WBPhenotype_0000781
    obo:IAO_0000115 "Any variation in the extremely thin elongated cytoplasmic filament, usually composed principally of actin protein to form a myofilament lattice, as in muscle cells compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "thin filament abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "thin filament variant" ;
    oboInOwl:id "WBPhenotype:0000781" ;
    a owl:Class ;
    rdfs:label "body wall muscle thin filament variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001889 .

obo:WBPhenotype_0000782
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a robust elongated cytoplasmic filament composed principally of myosin protein compared to control animals. In C. elegans, thick filaments also contain paramyosin and twitchin (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "thick filament abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "thick filament variant" ;
    oboInOwl:id "WBPhenotype:0000782" ;
    a owl:Class ;
    rdfs:label "body wall muscle thick filament variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001889 .

obo:WBPhenotype_0000783
    obo:IAO_0000115 "Animals lack the planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000783" ;
    a owl:Class ;
    rdfs:label "M line absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001891 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002000
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0031430
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005863
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000784
    obo:IAO_0000115 "Males exhibit variations in the time of onset or duration of the fertile period owing to differences in sperm competence and/or function compared to control animals." ;
    oboInOwl:hasNarrowSynonym "male fertility abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000784" ;
    a owl:Class ;
    rdfs:label "male fertility variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000145 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000279
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000056
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000785
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular body part compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body part pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000785" ;
    a owl:Class ;
    rdfs:label "body part pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000278 .

obo:WBPhenotype_0000786
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency along a particular body axis compared to control." ;
    oboInOwl:hasNarrowSynonym "body axis pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000786" ;
    a owl:Class ;
    rdfs:label "body axis pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000278 .

obo:WBPhenotype_0000787
    obo:IAO_0000115 "Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the posterior body axis compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000787" ;
    a owl:Class ;
    rdfs:label "posterior pale" ;
    rdfs:subClassOf obo:WBPhenotype_0000984, obo:WBPhenotype_0001261 .

obo:WBPhenotype_0000788
    obo:IAO_0000115 "Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the anterior body axis compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000788" ;
    a owl:Class ;
    rdfs:label "anterior pale" ;
    rdfs:subClassOf obo:WBPhenotype_0000971, obo:WBPhenotype_0001261 .

obo:WBPhenotype_0000789
    obo:IAO_0000115 "Animals respond to fluoxetine at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000789" ;
    a owl:Class ;
    rdfs:label "fluoxetine hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_5118
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000790
    obo:IAO_0000115 "Animals fail to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000790" ;
    a owl:Class ;
    rdfs:label "fluoxetine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_5118
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000791
    obo:IAO_0000115 "The nose of an animal fails to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000791" ;
    a owl:Class ;
    rdfs:label "nose resistant to fluoxetine" ;
    rdfs:subClassOf obo:WBPhenotype_0000790 .

obo:WBPhenotype_0000792
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the anatomy contained in the anterior region, compared to control animals." ;
    oboInOwl:hasExactSynonym "anterior region morphology variant" ;
    oboInOwl:hasNarrowSynonym "anterior body morphology abnormal", "anterior region morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000792" ;
    a owl:Class ;
    rdfs:label "anterior body morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0000581 .

obo:WBPhenotype_0000793
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the anatomy contained in the posterior region, compared to control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001490" ;
    oboInOwl:hasExactSynonym "posterior region morphology variant" ;
    oboInOwl:hasNarrowSynonym "posterior body morphology abnormal", "posterior region morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000793" ;
    a owl:Class ;
    rdfs:label "posterior body morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0000581 .

obo:WBPhenotype_0000794
    obo:IAO_0000115 "The posterior part of the worm exhibits a reduced girth compared to a control animal of the same developmental stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000794" ;
    a owl:Class ;
    rdfs:label "posterior body thin" ;
    rdfs:subClassOf obo:WBPhenotype_0000793 .

obo:WBPhenotype_0000795
    obo:IAO_0000115 "Variations in the specific actions or reactions of one of the longitudinal axes of the extended body of the worm in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "body axis behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000795" ;
    a owl:Class ;
    rdfs:label "body axis behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000522 .

obo:WBPhenotype_0000796
    obo:IAO_0000115 "The movement of the posterior part of the worm is not coordinated with the rest of the body." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000796" ;
    a owl:Class ;
    rdfs:label "posterior body uncoordinated" ;
    rdfs:subClassOf obo:WBPhenotype_0000797 .

obo:WBPhenotype_0000797
    obo:IAO_0000115 "Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the tail of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "posterior body behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000797" ;
    a owl:Class ;
    rdfs:label "posterior body behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000795 .

obo:WBPhenotype_0000798
    obo:IAO_0000115 "Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the head of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "anterior body behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000798" ;
    a owl:Class ;
    rdfs:label "anterior body behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000795 .

obo:WBPhenotype_0000799
    obo:IAO_0000115 "Variations in the progression of an animal's anatomy contained in the anterior region over time, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "anterior region development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000799" ;
    a owl:Class ;
    rdfs:label "anterior region development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000578 .

obo:WBPhenotype_0000800
    obo:IAO_0000115 "Variations in the progression of an animal's anatomy contained in the posterior region over time, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "posterior region development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000800" ;
    a owl:Class ;
    rdfs:label "posterior region development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000578 .

obo:WBPhenotype_0000801
    obo:IAO_0000115 "Variations in the progression of an animal's anatomy contained in the ventral region over time, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "ventral region development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000801" ;
    a owl:Class ;
    rdfs:label "ventral region development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000578 .

obo:WBPhenotype_0000802
    obo:IAO_0000115 "Variations in the progression of an animal's anatomy contained in the dorsal region over time, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "dorsal region development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000802" ;
    a owl:Class ;
    rdfs:label "dorsal region development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000578 .

obo:WBPhenotype_0000803
    obo:IAO_0000115 "Variations in the progression of the anterior end of the animal over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "head development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000803" ;
    a owl:Class ;
    rdfs:label "head development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000579 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001227
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060322
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000804
    obo:IAO_0000115 "Variations in the progression of the overall structure or appearance of the animal over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000804" ;
    a owl:Class ;
    rdfs:label "body development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000579 .

obo:WBPhenotype_0000805
    obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the tail over time, from its formation to the mature structure, compared to control. The tail includes the posterior region that spans from the rectum to the end." ;
    oboInOwl:hasNarrowSynonym "tail development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000805" ;
    a owl:Class ;
    rdfs:label "tail development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000579 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005741
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000806
    obo:IAO_0000115 "Hermaphrodites exhibit variations in the time of onset or duration of the fertile period, or variations in the production of viable offspring, including number and state of fertilized eggs laid, compared to controls." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite fertility abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000806" ;
    a owl:Class ;
    rdfs:label "hermaphrodite fertility variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000145 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000274
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007849
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000807
    obo:IAO_0000115 "The descendants of the G1 or G2 exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "G lineages abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000807" ;
    a owl:Class ;
    rdfs:label "G lineages variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000808
    obo:IAO_0000115 "The descendants of the K precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "K lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000808" ;
    a owl:Class ;
    rdfs:label "K lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000809
    obo:IAO_0000115 "The descendants of a male specific precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "male specific lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000809" ;
    a owl:Class ;
    rdfs:label "male specific lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000810
    obo:IAO_0000115 "Any variation in the progression of a blast cell (precursor cell) over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "blast cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000810" ;
    a owl:Class ;
    rdfs:label "blast cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006783
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000811
    obo:IAO_0000115 "Any variation in the progression of an epithelial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "epithelial cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000811" ;
    a owl:Class ;
    rdfs:label "epithelial cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002064
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000812
    obo:IAO_0000115 "Variations in the progression of the immature germ cell over time, from its formation from precursors to the mature structure (gamete) compared to control." ;
    oboInOwl:hasNarrowSynonym "germ cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "germline development abnormal" ;
    oboInOwl:id "WBPhenotype:0000812" ;
    a owl:Class ;
    rdfs:label "germ cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000774 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007281
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000813
    obo:IAO_0000115 "Any variation in the progression of a gland cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "gland cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000813" ;
    a owl:Class ;
    rdfs:label "gland cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0003670
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000814
    obo:IAO_0000115 "Any variation in the progression of a marginal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A marginal cell is a pharyngeal cell that connects the basement membrane to the apices of the triangle-shaped pharyngeal lumen." ;
    oboInOwl:hasNarrowSynonym "marginal cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000814" ;
    a owl:Class ;
    rdfs:label "marginal cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000619, obo:WBPhenotype_0000707 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0003673
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000815
    obo:IAO_0000115 "Any variation in the progression of a muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "muscle cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000815" ;
    a owl:Class ;
    rdfs:label "muscle cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000622 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0055001
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000816
    obo:IAO_0000115 "Variations in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "neuron development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000816" ;
    a owl:Class ;
    rdfs:label "neuron development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000623 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048666
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000817
    obo:IAO_0000115 "Variations in the progression of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) over time from an initial condition to a later condition compared to control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "uterine vulval cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000817" ;
    a owl:Class ;
    rdfs:label "uterine vulval cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000624 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006790
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000818
    obo:IAO_0000115 "Activity characteristic of an adult worm is altered compared to control." ;
    oboInOwl:hasNarrowSynonym "adult behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000818" ;
    a owl:Class ;
    rdfs:label "adult behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000819 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030534
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000819
    obo:IAO_0000115 "Behavior characteristic of postembryonic stage(s) is altered compared to control." ;
    oboInOwl:hasNarrowSynonym "postembryonic behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000819" ;
    a owl:Class ;
    rdfs:label "postembryonic behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001000 .

obo:WBPhenotype_0000820
    obo:IAO_0000115 "Activity characteristic of an embryo is altered compared to control." ;
    oboInOwl:hasNarrowSynonym "embryonic behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000820" ;
    a owl:Class ;
    rdfs:label "embryonic behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001000 .

obo:WBPhenotype_0000821
    obo:IAO_0000115 "Animals exhibit variations in sex-specific behaviors compared to control." ;
    oboInOwl:hasNarrowSynonym "sexually dimorphic behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000821" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "sexually dimorphic behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 .

obo:WBPhenotype_0000822
    obo:IAO_0000115 "Any variation in the processes that govern the sexually dimorphic development of germline or somatic tissue compared to control." ;
    oboInOwl:hasNarrowSynonym "sex determination abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "sex specific development abnormal" ;
    oboInOwl:id "WBPhenotype:0000822" ;
    a owl:Class ;
    rdfs:label "sex determination variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000930 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007530
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000823
    obo:IAO_0000115 "Nuclear divisions in the germ line are either expanded are reduced compared to control." ;
    oboInOwl:hasBroadSynonym "Glp" ;
    oboInOwl:hasExactSynonym "germ line proliferation abnormal" ;
    oboInOwl:hasNarrowSynonym "germline proliferation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "germ cell proliferation abnormal" ;
    oboInOwl:id "WBPhenotype:0000823" ;
    a owl:Class ;
    rdfs:label "germline proliferation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000812 .

obo:WBPhenotype_0000824
    obo:IAO_0000115 "The descendants of an embryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "embryonic cell lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000824" ;
    a owl:Class ;
    rdfs:label "embryonic cell lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000093 .

obo:WBPhenotype_0000825
    obo:IAO_0000115 "The descendants of a postembryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "postembryonic cell lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000825" ;
    a owl:Class ;
    rdfs:label "postembryonic cell lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000093 .

obo:WBPhenotype_0000826
    obo:IAO_0000115 "The descendants of H1 or H2 cells exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "H lineages abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000826" ;
    a owl:Class ;
    rdfs:label "H lineages variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000827
    obo:IAO_0000115 "The descendants of any of the V precursor cells (V1-V6) exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "V lineages abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000827" ;
    a owl:Class ;
    rdfs:label "V lineages variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000828
    obo:IAO_0000115 "The descendants of TL or TR cells exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "T lineages abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000828" ;
    a owl:Class ;
    rdfs:label "T lineages variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000829
    obo:IAO_0000115 "The descendants of Q L or QR cells exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "Q lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000829" ;
    a owl:Class ;
    rdfs:label "Q lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0008593
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000830
    obo:IAO_0000115 "The descendants of the B cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "B lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000830" ;
    a owl:Class ;
    rdfs:label "B lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0008608
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000831
    obo:IAO_0000115 "The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "Y lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000831" ;
    a owl:Class ;
    rdfs:label "Y lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809 .

obo:WBPhenotype_0000832
    obo:IAO_0000115 "The descendants of the C blastomere exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "C lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000832" ;
    a owl:Class ;
    rdfs:label "C lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000824 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0008588
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000833
    obo:IAO_0000115 "The descendants of the U cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "U lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000833" ;
    a owl:Class ;
    rdfs:label "U lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809 .

obo:WBPhenotype_0000834
    obo:IAO_0000115 "The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "E lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000834" ;
    a owl:Class ;
    rdfs:label "E lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000824 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005208
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000835
    obo:IAO_0000115 "The descendants of the F cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "F lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000835" ;
    a owl:Class ;
    rdfs:label "F lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809 .

obo:WBPhenotype_0000836
    obo:IAO_0000115 "The descendants of a gonadal precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "gonadal lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000836" ;
    a owl:Class ;
    rdfs:label "gonadal lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000837
    obo:IAO_0000115 "The descendants of a gonadal precursor cell exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite gonadal lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000837" ;
    a owl:Class ;
    rdfs:label "hermaphrodite gonadal lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000836 .

obo:WBPhenotype_0000838
    obo:IAO_0000115 "The descendants of a gonadal precursor cell exhibit altered developmental programs in the male compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "male gonadal lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000838" ;
    a owl:Class ;
    rdfs:label "male gonadal lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809, obo:WBPhenotype_0000836 .

obo:WBPhenotype_0000839
    obo:IAO_0000115 "Z1 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "Z1 hermaphrodite lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000839" ;
    a owl:Class ;
    rdfs:label "Z1 hermaphrodite lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000837 .

obo:WBPhenotype_0000840
    obo:IAO_0000115 "Z4 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "Z4 hermaphrodite lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000840" ;
    a owl:Class ;
    rdfs:label "Z4 hermaphrodite lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000837 .

obo:WBPhenotype_0000841
    obo:IAO_0000115 "Z1 descendents exhibit altered developmental programs in the male compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "Z1 male lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000841" ;
    a owl:Class ;
    rdfs:label "Z1 male lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000838 .

obo:WBPhenotype_0000842
    obo:IAO_0000115 "Z4 descendants exhibit altered developmental programs in the male compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "Z4 male lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000842" ;
    a owl:Class ;
    rdfs:label "Z4 male lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000838 .

obo:WBPhenotype_0000843
    obo:IAO_0000115 "The number of cross progeny sired by males is reduced compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000843" ;
    a owl:Class ;
    rdfs:label "male mating efficiency reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000648 .

obo:WBPhenotype_0000844
    obo:IAO_0000115 "Pharyngeal pumping is not influenced by serotonin treatment in the same manner as control animals." ;
    oboInOwl:hasNarrowSynonym "serotonin induced pumping abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000844" ;
    a owl:Class ;
    rdfs:label "serotonin induced pumping variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001232, obo:WBPhenotype_0001285 .

obo:WBPhenotype_0000845
    obo:IAO_0000115 "Animals exhibit variations in the response to the addition of levamisole compared to that observed in control animals. Levamisole is a cholinergic agonist." ;
    oboInOwl:hasNarrowSynonym "levamisole response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "tetramisole response abnormal" ;
    oboInOwl:id "WBPhenotype:0000845" ;
    a owl:Class ;
    rdfs:label "levamisole response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0000846
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process in the region of the vesicle-filled varicosities of the synapse compared to control." ;
    oboInOwl:hasNarrowSynonym "presynaptic region physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000846" ;
    a owl:Class ;
    rdfs:label "presynaptic region physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000584 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:GO_0098793
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000847
    obo:IAO_0000115 "Animals display variations in the distribution of the constituents that make up the synaptic machinery such as those required for priming, docking or fusion of vesicles at the active zone, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "presynaptic component localization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "synaptic component localization abnormal", "synaptic machinery localization abnormal" ;
    oboInOwl:id "WBPhenotype:0000847" ;
    a owl:Class ;
    rdfs:label "presynaptic component localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001321 .

obo:WBPhenotype_0000848
    obo:IAO_0000115 "The developmental progression of an animal over time, from its formation to its mature structure is delayed compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000848" ;
    a owl:Class ;
    rdfs:label "developmental delay" ;
    rdfs:subClassOf obo:WBPhenotype_0000438 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000502
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0032502
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000849
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for an amphid to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "amphid physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000849" ;
    a owl:Class ;
    rdfs:label "amphid physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000652 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005391
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000850
    obo:IAO_0000115 "Animal does not respond to stroking in the anterior body region with a hair or similar fiber compared to control. In C. elegans, the anterior region is defined as the body region that lies between the posterior bulb of the pharynx and the vulva." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "touch insensitive anterior body" ;
    oboInOwl:id "WBPhenotype:0000850" ;
    a owl:Class ;
    rdfs:label "touch resistant anterior body" ;
    rdfs:subClassOf obo:WBPhenotype_0000456 .

obo:WBPhenotype_0000851
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the ciliated neuron to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "ciliated neuron physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000851" ;
    a owl:Class ;
    rdfs:label "ciliated neuron physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006816
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000852
    obo:IAO_0000115 "Variations in the progression of a free-floating spherical cell lying in the pseudocoelomic cavity of animals that can endocytose many compounds, possibly for immune surveillance, over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "coelomocyte development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000852" ;
    a owl:Class ;
    rdfs:label "coelomocyte development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000618 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005751
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000853
    obo:IAO_0000115 "Variations in the bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum, compared to control." ;
    oboInOwl:hasNarrowSynonym "intraflagellar transport abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "IFT abnormal" ;
    oboInOwl:id "WBPhenotype:0000853" ;
    a owl:Class ;
    rdfs:label "intraflagellar transport variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000851 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042073
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000854
    obo:IAO_0000115 "Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is disrupted." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ift defective" ;
    oboInOwl:id "WBPhenotype:0000854" ;
    a owl:Class ;
    rdfs:label "intraflagellar transport defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000853 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042073
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000855
    obo:IAO_0000115 "Variations in the progression of the fluid-filled space which separates the body wall from internal organs over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "pseudocoelom development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000855" ;
    a owl:Class ;
    rdfs:label "pseudocoelom development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000200 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005745
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000856
    obo:IAO_0000115 "Any variation in the progression of a gland cell of the secretory-excretory system over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "excretory gland cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000856" ;
    a owl:Class ;
    rdfs:label "excretory gland cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000620, obo:WBPhenotype_0000813 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005776
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000857
    obo:IAO_0000115 "Variations in the progression of a protokidney cell with an internal lumen that is suggested to collect and secrete salt solutions outward via the excretory sinus, over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "excretory cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "excretory canal cell development abnormal" ;
    oboInOwl:id "WBPhenotype:0000857" ;
    a owl:Class ;
    rdfs:label "excretory cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000621 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005812
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000858
    obo:IAO_0000115 "Variations in the progression of an interfacial epithelial cell which forms a lumen to receive the outflow of the excretory gland and excretory canal cells, over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "excretory duct cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000858" ;
    a owl:Class ;
    rdfs:label "excretory duct cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000621 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0004540
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000859
    obo:IAO_0000115 "Variations in the progression of an interfacial epithelial cell which links excretory duct to hypodermis, over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "excretory socket cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "excretory pore cell development abnormal" ;
    oboInOwl:id "WBPhenotype:0000859" ;
    a owl:Class ;
    rdfs:label "excretory socket cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000621 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0004534
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000860
    obo:IAO_0000115 "Variations in the progression of muscle cells that lack transverse striations in its constituent fibers and are almost always involuntary, over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "nonstriated muscle development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000860" ;
    a owl:Class ;
    rdfs:label "nonstriated muscle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000622 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005780
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000861
    obo:IAO_0000115 "Any variation in the progression of the principal muscle cell type whose contractile activity generates body motion in the nematode over time compared to control. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas)." ;
    oboInOwl:hasExactSynonym "body wall muscle development abnormal" ;
    oboInOwl:hasNarrowSynonym "body wall muscle cell development abnormal", "body wall muscle cell development variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "muscle belly development abnormal", "somatic muscle development abnormal", "striated muscle development abnormal" ;
    oboInOwl:id "WBPhenotype:0000861" ;
    a owl:Class ;
    rdfs:label "body wall muscle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000921 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006804
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000862
    obo:IAO_0000115 "Worms appears turgid or swollen as a result of an excess number of eggs being retained in the uterus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000862" ;
    a owl:Class ;
    rdfs:label "bloated" ;
    rdfs:subClassOf obo:WBPhenotype_0000545 .

obo:WBPhenotype_0000863
    obo:IAO_0000115 "Males exhibit a reduction in the production of new individuals owing to defects in sperm competence and/or function compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000863" ;
    a owl:Class ;
    rdfs:label "male fertility reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000784 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001834
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000056
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000864
    obo:IAO_0000115 "Cessation of development during the initial period of elongation. In C. elegans, this period refers to the conversion of the bean-shaped embryo into the two-fold- shaped embryo." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000864" ;
    a owl:Class ;
    rdfs:label "early elongation arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000867 .

obo:WBPhenotype_0000865
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for a amphid sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "amphid sheath cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000865" ;
    a owl:Class ;
    rdfs:label "amphid sheath cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000849 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006754
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000866
    obo:IAO_0000115 "Germ cells fail to undergo meiotic differentiation to form mature gametes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000866" ;
    a owl:Class ;
    rdfs:label "germ cell arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000823 .

obo:WBPhenotype_0000867
    obo:IAO_0000115 "Cessation of development during any stage occurring after fertilization and until hatching compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000867" ;
    a owl:Class ;
    rdfs:label "embryonic arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000868
    obo:IAO_0000115 "All parts of the animal are immobilized except for the head." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000868" ;
    a owl:Class ;
    rdfs:label "paralyzed body" ;
    rdfs:subClassOf obo:WBPhenotype_0000644 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000763
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005738
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000869
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0001401 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000869" ;
    a owl:Class ;
    rdfs:label "obsolete mitochondria morphology variant muscle" ;
    owl:deprecated true .

obo:WBPhenotype_0000870
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0001401 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000870" ;
    a owl:Class ;
    rdfs:label "obsolete mitochondria morphology variant epithelial" ;
    owl:deprecated true .

obo:WBPhenotype_0000871
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0001402 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000871" ;
    a owl:Class ;
    rdfs:label "obsolete connected mitochondria epithelial" ;
    owl:deprecated true .

obo:WBPhenotype_0000872
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0001402 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000872" ;
    a owl:Class ;
    rdfs:label "obsolete connected mitochodria muscle" ;
    owl:deprecated true .

obo:WBPhenotype_0000873
    obo:IAO_0000115 "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G1 phase of the mitotic cell cycle just before entry into S phase, compared to control cells." ;
    oboInOwl:hasNarrowSynonym "G1 checkpoint abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000873" ;
    a owl:Class ;
    rdfs:label "G1 checkpoint variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000741 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0044819
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000874
    obo:IAO_0000115 "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G2 phase of the mitotic cell cycle just before entry into M phase, nuclear division, compared to control cells." ;
    oboInOwl:hasNarrowSynonym "G2 checkpoint abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000874" ;
    a owl:Class ;
    rdfs:label "G2 checkpoint variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000741 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0044818
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000875
    obo:IAO_0000115 "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the S phase of the mitotic cell cycle, which ensures DNA replication is complete, compared to control cells." ;
    oboInOwl:hasNarrowSynonym "S phase checkpoint abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000875" ;
    a owl:Class ;
    rdfs:label "S phase checkpoint variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000741 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0031573
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000876
    obo:IAO_0000115 "Animals exhibit variations in their response to osmotic stress compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism osmotic stress response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000876" ;
    a owl:Class ;
    rdfs:label "organism osmotic stress response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006970
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000877
    obo:IAO_0000115 "Any variation in the progression of a sheath cell of the amphid sensillum over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "amphid sheath cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000877" ;
    a owl:Class ;
    rdfs:label "amphid sheath cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000950 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006754
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000878
    obo:IAO_0000115 "Any variation in the progression of a chemosensory neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "chemosensory neuron development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000878" ;
    a owl:Class ;
    rdfs:label "chemosensory neuron development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000816 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005837
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000879
    obo:IAO_0000115 "Animals exhibit variations in the processes that are required to maintain the length of telomeric DNA from generation to generation compared to control." ;
    oboInOwl:hasNarrowSynonym "telomere length regulation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000879" ;
    a owl:Class ;
    rdfs:label "telomere length regulation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001673 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1904356
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000880
    obo:IAO_0000115 "Any variation in the processes that influence the generation of neuronal extensions, that carry efferent (outgoing) action potentials from the cell body towards target cells compared to control." ;
    oboInOwl:hasNarrowSynonym "axon development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "axonogenesis abnormal" ;
    oboInOwl:id "WBPhenotype:0000880" ;
    a owl:Class ;
    rdfs:label "axon development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000944 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0061564
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000881
    obo:IAO_0000115 "Animals exhibit variations in the placement of the microtuble-based dendritic projections in relation to the sensillum neuron, from that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000881" ;
    a owl:Class ;
    rdfs:label "cilia mislocalized" ;
    rdfs:subClassOf obo:WBPhenotype_0001526 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006816
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000882
    obo:IAO_0000115 "Any variation in the processes that influence the generation of neuronal extensions, that carry afferent (incoming) action potentials towards the cell body compared to control." ;
    oboInOwl:hasNarrowSynonym "dendrite development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000882" ;
    a owl:Class ;
    rdfs:label "dendrite development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000944 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016358
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000883
    obo:IAO_0000115 "Variations in the progression of the major zone of overlapping axons in the head, which encircles the isthmus of the pharynx to form a tightly packed ring-like structure on the outside of the pharynx, over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "nerve ring development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000883" ;
    a owl:Class ;
    rdfs:label "nerve ring development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000945 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006749
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000884
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of either of a set of two ciliated wing neurons, AWBL or AWBR, of the amphid sensilla, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "AWB morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000884" ;
    a owl:Class ;
    rdfs:comment "WBbt:0005671." ;
    rdfs:label "AWB morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000256 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005671
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000885
    obo:IAO_0000115 "Any variation in the removal of a cell corpse, by a neighboring cell or a phagocyte compared to control." ;
    oboInOwl:hasNarrowSynonym "engulfment abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "phagocytosis abnormal" ;
    oboInOwl:id "WBPhenotype:0000885" ;
    a owl:Class ;
    rdfs:label "engulfment variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043652
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000886
    obo:IAO_0000115 "Animals exhibit variations compared to a given control." ;
    oboInOwl:hasExactSynonym "Abnormal", "variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "not WT", "not wildtype" ;
    oboInOwl:id "WBPhenotype:0000886" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "nematode phenotype" .

obo:WBPhenotype_0000887
    obo:IAO_0000115 "Animals exhibit variations in hermaphrodite-specific behaviors compared to control." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000887" ;
    a owl:Class ;
    rdfs:label "hermaphrodite behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000821 .

obo:WBPhenotype_0000888
    obo:IAO_0000115 "Animals exhibit variations in male-specific behaviors compared to control." ;
    oboInOwl:hasNarrowSynonym "male behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000888" ;
    a owl:Class ;
    rdfs:label "male behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000821 .

obo:WBPhenotype_0000889
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required to carry out sex-specific activities or to be able to perceive and respond to sex-specific stimuli compared to control." ;
    oboInOwl:hasNarrowSynonym "sexually dimorphic physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000889" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "sexually dimorphic physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000576 .

obo:WBPhenotype_0000890
    obo:IAO_0000115 "Larva exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals." ;
    oboInOwl:hasNarrowSynonym "larval pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000890" ;
    a owl:Class ;
    rdfs:label "larval pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001009 .

obo:WBPhenotype_0000891
    obo:IAO_0000115 "Adult animals appear unusually transparent when compared to control." ;
    oboInOwl:hasBroadSynonym "Clr" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000891" ;
    a owl:Class ;
    rdfs:label "clear adult" ;
    rdfs:subClassOf obo:WBPhenotype_0000346, obo:WBPhenotype_0001010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000964
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000041
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000892
    obo:IAO_0000115 "Nuclear divisions in the germ line of hermaphrodites are either expanded are reduced compared to control." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite germline proliferation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "hermaphrodite germ cell proliferation abnormal", "hermaphrodite germ line proliferation abnormal" ;
    oboInOwl:id "WBPhenotype:0000892" ;
    a owl:Class ;
    rdfs:label "hermaphrodite germline proliferation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000823 .

obo:WBPhenotype_0000893
    obo:IAO_0000115 "Nuclear divisions in the germ line of male animals are either expanded are reduced compared to control." ;
    oboInOwl:hasNarrowSynonym "male germline proliferation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "male germ cell proliferation abnormal", "male germ line proliferation abnormal" ;
    oboInOwl:id "WBPhenotype:0000893" ;
    a owl:Class ;
    rdfs:label "male germline proliferation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000823 .

obo:WBPhenotype_0000894
    obo:IAO_0000115 "Variations in the ability of a relatively unspecialized cell to acquire the specialized features of a mature gamete compared to control." ;
    oboInOwl:hasNarrowSynonym "germ cell differentiation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000894" ;
    a owl:Class ;
    rdfs:label "germ cell differentiation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000774 .

obo:WBPhenotype_0000895
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000670 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000895" ;
    a owl:Class ;
    rdfs:label "obsolete spermatocyte germ cell differentiation abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000896
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000186 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000896" ;
    a owl:Class ;
    rdfs:label "obsolete oocyte germ cell differentiation abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0000897
    obo:IAO_0000115 "Variations in the material made up of fibers forming a framework and support structure for body tissues and organs compared to control." ;
    oboInOwl:hasNarrowSynonym "connective tissue abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000897" ;
    a owl:Class ;
    rdfs:label "connective tissue development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000200 .

obo:WBPhenotype_0000898
    obo:IAO_0000115 "Any variation in the morphological appearance of blast cells compared to control animals." ;
    oboInOwl:hasNarrowSynonym "blast cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000898" ;
    a owl:Class ;
    rdfs:label "blast cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006783
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000899
    obo:IAO_0000115 "Any variation in the morphological appearance of epithelial cells compared to control animals." ;
    oboInOwl:hasNarrowSynonym "epithelial cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000899" ;
    a owl:Class ;
    rdfs:label "epithelial cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003672
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000900
    obo:IAO_0000115 "Any variation in the morphological appearance of germ cells compared to control animals." ;
    oboInOwl:hasNarrowSynonym "germ cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000900" ;
    a owl:Class ;
    rdfs:label "germ cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006796
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000901
    obo:IAO_0000115 "Any variation in the morphological appearance of gland cells compared to control animals." ;
    oboInOwl:hasNarrowSynonym "gland cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000901" ;
    a owl:Class ;
    rdfs:label "gland cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003670
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000902
    obo:IAO_0000115 "Any variation in the morphological appearance of intestinal cells compared to control animals." ;
    oboInOwl:hasNarrowSynonym "intestinal cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000902" ;
    a owl:Class ;
    rdfs:label "intestinal cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000710, obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005792
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000903
    obo:IAO_0000115 "Any variation in the morphological appearance of marginal cells compared to control animals." ;
    oboInOwl:hasNarrowSynonym "marginal cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000903" ;
    a owl:Class ;
    rdfs:label "marginal cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003673
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000904
    obo:IAO_0000115 "Any variation in the morphological appearance of muscle cells compared to control animals." ;
    oboInOwl:hasNarrowSynonym "muscle cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000904" ;
    a owl:Class ;
    rdfs:label "muscle cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000603, obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003675
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000905
    obo:IAO_0000115 "Animals display variations in the structure or organization of components of the neuronal cell internal to the cell itself or in relation to the cellular environment compared to control. A neuron is a major cell type of nervous tissue specialized for transmission of information in the form of patterns of impulses." ;
    oboInOwl:hasNarrowSynonym "neuron morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000905" ;
    a owl:Class ;
    rdfs:comment "WBbt:0003679." ;
    rdfs:label "neuron morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000604, obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003679
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000906
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) compared to control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "uterine vulval cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000906" ;
    a owl:Class ;
    rdfs:label "uterine vulval cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 .

obo:WBPhenotype_0000907
    obo:IAO_0000115 "Any variation in the structural appearance of the caudal opening of the rectum in the tail compared to control animals." ;
    oboInOwl:hasNarrowSynonym "anus morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000907" ;
    a owl:Class ;
    rdfs:label "anus morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000598 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005364
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000908
    obo:IAO_0000115 "Any variation in the structural appearance of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) compared to control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000343" ;
    oboInOwl:hasExactSynonym "cloaca morphology abnormal" ;
    oboInOwl:hasNarrowSynonym "cloacal morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000908" ;
    a owl:Class ;
    rdfs:label "cloacal morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000598, obo:WBPhenotype_0000605 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005774
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000909
    obo:IAO_0000115 "Any variation in the structure or appearance of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "pharyngeal intestinal valve morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000909" ;
    a owl:Class ;
    rdfs:label "pharyngeal intestinal valve morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000598 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005767
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000910
    obo:IAO_0000115 "Any variation in the morphological appearance of the rectum compared to control animals." ;
    oboInOwl:hasNarrowSynonym "rectal morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000910" ;
    a owl:Class ;
    rdfs:label "rectal morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000598 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005773
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000911
    obo:IAO_0000115 "Any variation in the morphological appearance of coelomocytes compared to control animals." ;
    oboInOwl:hasNarrowSynonym "coelomocyte morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000911" ;
    a owl:Class ;
    rdfs:label "coelomocyte morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000599 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005751
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000912
    obo:IAO_0000115 "Any variation in the morphological appearance of pericellular components compared to control animals." ;
    oboInOwl:hasNarrowSynonym "pericellular component morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000912" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "pericellular component morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000520 .

obo:WBPhenotype_0000913
    obo:IAO_0000115 "Any variation in the morphological appearance of the basal lamina compared to control animals." ;
    oboInOwl:hasNarrowSynonym "basal lamina morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000913" ;
    a owl:Class ;
    rdfs:label "basal lamina morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000600 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005604
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000914
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "excretory gland cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000914" ;
    a owl:Class ;
    rdfs:label "excretory gland cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000601 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005776
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000915
    obo:IAO_0000115 "Adults show deficiencies in chroma resulting in increased translucency." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000915" ;
    a owl:Class ;
    rdfs:label "pale adult" ;
    rdfs:subClassOf obo:WBPhenotype_0000346, obo:WBPhenotype_0001261 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000328
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000041
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000916
    obo:IAO_0000115 "Any variation in the morphological appearance of the excretory cell compared to control animals." ;
    oboInOwl:hasNarrowSynonym "excretory cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "excretory canal cell morphology abnormal" ;
    oboInOwl:id "WBPhenotype:0000916" ;
    a owl:Class ;
    rdfs:label "excretory cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000601 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005812
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000917
    obo:IAO_0000115 "Any variation in the morphological appearance of the excretory duct cell compared to control animals." ;
    oboInOwl:hasNarrowSynonym "excretory duct cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000917" ;
    a owl:Class ;
    rdfs:label "excretory duct cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000601 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004540
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000918
    obo:IAO_0000115 "Any variation in the morphological appearance of the excretory socket cell compared to control animals." ;
    oboInOwl:hasNarrowSynonym "excretory socket cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000918" ;
    a owl:Class ;
    rdfs:label "excretory socket cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000601 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004534
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000919
    obo:IAO_0000115 "Any variation in the progression of the region of a body wall muscle cell that contains the myofilament lattice (adjacent to the hypodermis) over time, from its initial state to the fully differentiated state compared to control." ;
    oboInOwl:hasNarrowSynonym "spindle body wall muscle cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "filament lattice body wall muscle cell development abnormal", "spindle body wall muscle cell development variant" ;
    oboInOwl:id "WBPhenotype:0000919" ;
    a owl:Class ;
    rdfs:label "body wall muscle cell spindle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000087 .

obo:WBPhenotype_0000920
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000861 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000920" ;
    a owl:Class ;
    rdfs:label "obsolete body wall muscle cell development variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000921
    obo:IAO_0000115 "Variations in the progression of muscle cells that contain fibers that are divided by transverse bands into striations, over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "striated muscle development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000921" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "striated muscle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000622 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005779
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000922
    obo:IAO_0000115 "Any variation in the progression of somatic (striated) muscles that run longitudinally in males over time from its initial formation to its mature form compared to control. In C. elegans males have 3 additional sets of sex-specific longitudinal muscles (anterior and posterior outer, anterior and posterior inner, and caudal) that contribute to the body wall musculature (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "male longitudinal muscle development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000922" ;
    a owl:Class ;
    rdfs:label "male longitudinal muscle development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000921 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006909
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000923
    obo:IAO_0000115 "Any variation in the morphological appearance of the nonstriated muscle compared to control animals." ;
    oboInOwl:hasNarrowSynonym "nonstriated muscle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000923" ;
    a owl:Class ;
    rdfs:label "nonstriated muscle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000603 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005780
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000924
    obo:IAO_0000115 "Any variation in the morphological appearance of the striated muscle compared to control animals." ;
    oboInOwl:hasNarrowSynonym "striated muscle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000924" ;
    a owl:Class ;
    rdfs:label "striated muscle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000603 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005779
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000925
    obo:IAO_0000115 "Any variation in the morphological appearance of the sex muscles compared to control animals." ;
    oboInOwl:hasNarrowSynonym "sex muscle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000925" ;
    a owl:Class ;
    rdfs:label "sex muscle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000923 .

obo:WBPhenotype_0000926
    obo:IAO_0000115 "Any variation in the morphological appearance of the body wall muscle compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body wall muscle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Dim" ;
    oboInOwl:id "WBPhenotype:0000926" ;
    a owl:Class ;
    rdfs:label "body wall muscle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000924 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005813
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000927
    obo:IAO_0000115 "Any variation in the morphological appearance of the male longitudinal muscle compared to control animals." ;
    oboInOwl:hasNarrowSynonym "male longitudinal muscle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000927" ;
    a owl:Class ;
    rdfs:label "male longitudinal muscle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000924 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006909
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000928
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required to carry out male-specific activities or to be able to perceive and respond to male-specific stimuli compared to control." ;
    oboInOwl:hasNarrowSynonym "male physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000928" ;
    a owl:Class ;
    rdfs:label "male physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000889 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0007850
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000929
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required to carry out hermaphrodite-specific activities or to be able to perceive and respond to hermaphrodite-specific stimuli compared to control." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000929" ;
    a owl:Class ;
    rdfs:label "hermaphrodite physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000889 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0007849
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000930
    obo:IAO_0000115 "Variations in the progression of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "sexually dimorphic development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000930" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "sexually dimorphic development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005752
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000931
    obo:IAO_0000115 "Animals exhibit variations in their response to bisphenol A compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "bisphenol A response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000931" ;
    a owl:Class ;
    rdfs:label "bisphenol A response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000523 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_33216
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042221
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000932
    obo:IAO_0000115 "Animals respond to bisphenol A at a lower concentration or a shorter exposure time compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000932" ;
    a owl:Class ;
    rdfs:label "bisphenol A hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000931 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_33216
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000933
    obo:IAO_0000115 "The descendants of the MS blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "MS lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000933" ;
    a owl:Class ;
    rdfs:label "MS lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000824 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0008627
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000934
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any of its parts during a given developmental stage compared to control animals." ;
    oboInOwl:hasNarrowSynonym "developmental morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000934" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "developmental morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000535 .

obo:WBPhenotype_0000935
    obo:IAO_0000115 "The descendants of the D blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "D lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000935" ;
    a owl:Class ;
    rdfs:label "D lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000824 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0008589
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000936
    obo:IAO_0000115 "The descendants of the P4 blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "P4 lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000936" ;
    a owl:Class ;
    rdfs:label "P4 lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000824 .

obo:WBPhenotype_0000937
    obo:IAO_0000115 "The descendants of the W precursor cell exhibit any variation in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "W lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000937" ;
    a owl:Class ;
    rdfs:label "W lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000825 .

obo:WBPhenotype_0000938
    obo:IAO_0000115 "The descendants of any of the V precursor cells (V1-V6) in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "male V lineages abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000938" ;
    a owl:Class ;
    rdfs:label "male V lineages variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809 .

obo:WBPhenotype_0000939
    obo:IAO_0000115 "The descendants of TL or TR cells in male animals exhibit any variation in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "male T lineages abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000939" ;
    a owl:Class ;
    rdfs:label "male T lineages variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809 .

obo:WBPhenotype_0000940
    obo:IAO_0000115 "The descendants of any of the P precursor cells (P1-P12) in male animals exhibit any variation in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "male P lineages abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000940" ;
    a owl:Class ;
    rdfs:label "male P lineages variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809 .

obo:WBPhenotype_0000941
    obo:IAO_0000115 "The descendants of the M precursor cell in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals." ;
    oboInOwl:hasNarrowSynonym "male M lineage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000941" ;
    a owl:Class ;
    rdfs:label "male M lineage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000809 .

obo:WBPhenotype_0000942
    obo:IAO_0000115 "Any variation in the progression of an accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. An accessory cell supports sensory neurons." ;
    oboInOwl:hasNarrowSynonym "accessory cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000942" ;
    a owl:Class ;
    rdfs:label "accessory cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000623 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005762
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000943
    obo:IAO_0000115 "Any variation in the progression of a cluster of neuron cell bodies (somata) over time from its initial formation to its mature form compared to control." ;
    oboInOwl:hasNarrowSynonym "ganglion development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000943" ;
    a owl:Class ;
    rdfs:label "ganglion development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000623 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005189
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000944
    obo:IAO_0000115 "Variations in the progression of a neuronal extension (such as axons or dendrites) over time, from its formation to the mature structure compared to control." ;
    oboInOwl:hasNarrowSynonym "neurite development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000944" ;
    a owl:Class ;
    rdfs:label "neurite development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000816 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0031175
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000945
    obo:IAO_0000115 "Any variation in the progression of a dense feltwork of interwoven cytoplasmic processes of nerve cells (dendrites and axons) and support cells, over time from an initial condition to a later condition, compared to control." ;
    oboInOwl:hasNarrowSynonym "neuropil development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000945" ;
    a owl:Class ;
    rdfs:label "neuropil development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000623 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:UBERON_0002606
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000946
    obo:IAO_0000115 "Variations in the progression of a set of interacting or interdependent entities forming the pharyngeal nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses." ;
    oboInOwl:hasNarrowSynonym "pharyngeal nervous system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000946" ;
    a owl:Class ;
    rdfs:label "pharyngeal nervous system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000623 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005440
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000947
    obo:IAO_0000115 "Variations in the form, structure or composition of the material made up of fibers forming a framework and support structure for body tissues and organs compared to control." ;
    oboInOwl:hasNarrowSynonym "connective tissue morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000947" ;
    a owl:Class ;
    rdfs:label "connective tissue morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000912 .

obo:WBPhenotype_0000948
    obo:IAO_0000115 "Any variation in the appearance or structure of the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "cuticle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000948" ;
    a owl:Class ;
    rdfs:label "cuticle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000912 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005755
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000949
    obo:IAO_0000115 "Any variation in the appearance of the body cavity compared to control. In C. elegans , an aberrancy in the psedocoelom can involve an accumulation of fluids or fluorescent reporters." ;
    oboInOwl:hasNarrowSynonym "pseudocoelom morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000949" ;
    a owl:Class ;
    rdfs:label "pseudocoelom morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000912 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005745
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000950
    obo:IAO_0000115 "Any variation in the progression of a neuronal sheath cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A neuronal sheath cell is a structural cell that forms a specialized environment surrounding the sensory endings of a neuron." ;
    oboInOwl:hasNarrowSynonym "neuronal sheath cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000950" ;
    a owl:Class ;
    rdfs:label "neuronal sheath cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000942 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005811
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000951
    obo:IAO_0000115 "Any variation in the progression of a socket cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ;
    oboInOwl:hasNarrowSynonym "socket cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000951" ;
    a owl:Class ;
    rdfs:label "socket cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000942 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005750
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000952
    obo:IAO_0000115 "Any variation in the progression of a cluster of neuron somata located close to the nerve ring over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "anterior ganglion development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000952" ;
    a owl:Class ;
    rdfs:label "anterior ganglion development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005375
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000953
    obo:IAO_0000115 "Any variation in the progression of the ganglion that lies dorsally beside the nerve ring in the head over time from its initial formation to its mature form compared to control. In C. elegans, It contains neuron cell bodies that send their neuronal processes into the ring and longitudinal nerves, but form no local neuropil separate from the nerve ring. The dorsal ganglion is in close contact with the dorsal hypodermal cord (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "dorsal ganglion development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000953" ;
    a owl:Class ;
    rdfs:label "dorsal ganglion development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005214
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000954
    obo:IAO_0000115 "Any variation in the progression of the ganglion which lies above and behind the rectum in the tail, in close continuity with the anal hypodermal ridge over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "dorsorectal ganglia development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000954" ;
    a owl:Class ;
    rdfs:label "dorsorectal ganglia development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005212
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000955
    obo:IAO_0000115 "Any variation in the progression of the left and right lateral ganglia which lie beside the nerve ring in the head over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "lateral ganglia development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000955" ;
    a owl:Class ;
    rdfs:label "lateral ganglia development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005105
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000956
    obo:IAO_0000115 "Any variation in the progression of the left and right lumbar ganglia which lie behind the pre-anal ganglion in the tail, in lateral positions over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "lumbar ganglia development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000956" ;
    a owl:Class ;
    rdfs:label "lumbar ganglia development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005830
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000957
    obo:IAO_0000115 "Any variation in the progression of the neuron somata associated with the post-deirid over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "posterior lateral ganglion development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000957" ;
    a owl:Class ;
    rdfs:label "posterior lateral ganglion development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005465
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000958
    obo:IAO_0000115 "Any variation in the progression of the ganglion which lies at the posterior limit of the ventral nerve cord in the tail over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "preanal ganglion development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000958" ;
    a owl:Class ;
    rdfs:label "preanal ganglion development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005448
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000959
    obo:IAO_0000115 "Any variation in the progression of the ganglion which lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "retrovesicular ganglion development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000959" ;
    a owl:Class ;
    rdfs:label "retrovesicular ganglion development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005656
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000960
    obo:IAO_0000115 "Any variation in the progression of the ganglion which lies ventrally beside the nerve ring in the head, just anterior of the retrovesicular ganglion over time from its initial formation to its mature form compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "ventral ganglion development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000960" ;
    a owl:Class ;
    rdfs:label "ventral ganglion development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000943 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005298
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000961
    obo:IAO_0000115 "Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ;
    oboInOwl:hasNarrowSynonym "pattern of transgene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000961" ;
    a owl:Class ;
    rdfs:label "pattern of transgene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000111, obo:WBPhenotype_0000306 .

obo:WBPhenotype_0000962
    obo:IAO_0000115 "Any variation in the measured expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ;
    oboInOwl:hasNarrowSynonym "level of transgene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000962" ;
    a owl:Class ;
    rdfs:label "level of transgene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000306, obo:WBPhenotype_0002575 .

obo:WBPhenotype_0000963
    obo:IAO_0000115 "Males exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism compared to control animals." ;
    oboInOwl:hasNarrowSynonym "male pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000963" ;
    a owl:Class ;
    rdfs:label "male pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000527 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002247
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007850
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000964
    obo:IAO_0000115 "Animals fail to respond to the concentration of DMPP that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000964" ;
    a owl:Class ;
    rdfs:label "DMPP resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000681 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_4290
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000965
    obo:IAO_0000115 "Animals exhibit variations in the programmed cell death pathway that is triggered in cells other than germ cells and that is not subject to upstream checkpoint regulation." ;
    oboInOwl:hasNarrowSynonym "somatic cell death abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000965" ;
    a owl:Class ;
    rdfs:label "somatic cell death variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001172 .

obo:WBPhenotype_0000966
    obo:IAO_0000115 "Progressive decrease in brood size culminating, over generations, in the loss of reproductive ability and thus becoming effectively sterile." ;
    oboInOwl:hasBroadSynonym "Mrt" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000966" ;
    a owl:Class ;
    rdfs:label "germline mortal" ;
    rdfs:subClassOf obo:WBPhenotype_0000987 .

obo:WBPhenotype_0000967
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0001431 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000967" ;
    a owl:Class ;
    rdfs:comment "In the WS193 and WS200 versions of WormBase WBPhenotype:0000967 has term name \"male tail spike\"; In some older records the term ID WBPhenotype:0000967 had the term name \"male distal tip cell behavior abnormal\", which may reflect an earlier (now deprecated) usage of the term ID." ;
    rdfs:label "obsolete male tail spike" ;
    owl:deprecated true .

obo:WBPhenotype_0000968
    obo:IAO_0000115 "Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the tail compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000968" ;
    a owl:Class ;
    rdfs:label "tail spike variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000073 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006979
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000969
    obo:IAO_0000115 "Animals exhibit variations in the structure, organization or placement of the cells that support sensory neurons, compared to that observed in control animals. In C. elegans, this category collectively refers to socket cells, sheath cells, and structural cells, or their processes." ;
    oboInOwl:hasNarrowSynonym "accessory cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000969" ;
    a owl:Class ;
    rdfs:comment "WBbt:0005762." ;
    rdfs:label "accessory cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000604 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005762
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000970
    obo:IAO_0000115 "Embryos exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals ." ;
    oboInOwl:hasNarrowSynonym "embryonic pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000970" ;
    a owl:Class ;
    rdfs:label "embryonic pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001009 .

obo:WBPhenotype_0000971
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the anterior body axis compared to control." ;
    oboInOwl:hasNarrowSynonym "anterior pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000971" ;
    a owl:Class ;
    rdfs:label "anterior pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000786 .

obo:WBPhenotype_0000972
    obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the glia-like support cell of neuronal sensilla that ensheathes the dendrite tips and or processes of neurons, from that observed in control animals. In C. elegans, sheath cells have highly invaginated and vesiculated surfaces, which provide a specialized environment for dendritic structures." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001529" ;
    oboInOwl:hasExactSynonym "sensilium sheath cell morphology variant" ;
    oboInOwl:hasNarrowSynonym "neuronal sheath cell morphology abnormal", "sensilium sheath cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000972" ;
    a owl:Class ;
    rdfs:label "neuronal sheath cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000969, obo:WBPhenotype_0001528 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005811
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000973
    obo:IAO_0000115 "Animals exhibit an increased frequency of exchange of genetic material between non-sister chromatids of a pair of homologues." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000973" ;
    a owl:Class ;
    rdfs:label "homologous recombination increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000742 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035825
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000974
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required by a subset of interfacial cells to carry out its normal function or be able to perceive and respond to stimuli, compared to control. It can refer to socket cells, sheath cells and structural cells or their processes (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "accessory cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000974" ;
    a owl:Class ;
    rdfs:label "accessory cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000612 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005762
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000975
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for a neuronal sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "neuronal sheath cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000975" ;
    a owl:Class ;
    rdfs:label "neuronal sheath cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000974 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005811
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000976
    obo:IAO_0000115 "Any variation in the developmental process that results in the creation of defined areas or spaces within the ventral cord to which cells respond and eventually are instructed to differentiate compared to control." ;
    oboInOwl:hasNarrowSynonym "ventral cord patterning abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000976" ;
    a owl:Class ;
    rdfs:label "ventral cord patterning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000515 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000060
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005829
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000977
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the components of the gonad that are separate from the germline proper compared to control animals." ;
    oboInOwl:hasNarrowSynonym "somatic gonad morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000977" ;
    a owl:Class ;
    rdfs:label "somatic gonad morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001355 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005785
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000978
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the spermatheca to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "spermatheca physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000978" ;
    a owl:Class ;
    rdfs:label "spermatheca physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001197 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005319
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000979
    obo:IAO_0000115 "Animals exhibit defects in any physical or chemical process involved in the dilation of the distal spermatheca which is required for the oocyte exit from the gonad arm." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000979" ;
    a owl:Class ;
    rdfs:label "spermatheca dilation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000978 .

obo:WBPhenotype_0000980
    obo:IAO_0000115 "Any variation in the muscle contractions that control feeding compared to control. Contractions are necessary for bacterial uptake from the surrounding environment." ;
    oboInOwl:hasNarrowSynonym "pharyngeal contraction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000980" ;
    a owl:Class ;
    rdfs:label "pharyngeal contraction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000634 .

obo:WBPhenotype_0000981
    obo:IAO_0000115 "Animals exhibit variations in the meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids (non-motile sperm) compared to control." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000713" ;
    oboInOwl:hasExactSynonym "spermatocyte division variant" ;
    oboInOwl:hasNarrowSynonym "spermatocyte division abnormal", "spermatocyte meiosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000981" ;
    a owl:Class ;
    rdfs:label "spermatocyte meiosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000670 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_1903046
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006799
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000982
    obo:IAO_0000115 "Animals exhibit variations in the ability of a relatively unspecialized spermatocyte to acquire the properties of a spermatid cell compared to control." ;
    oboInOwl:hasNarrowSynonym "spermatid maturation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000982" ;
    a owl:Class ;
    rdfs:label "spermatid maturation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000670 .

obo:WBPhenotype_0000983
    obo:IAO_0000115 "Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) during sexual reproduction." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000983" ;
    a owl:Class ;
    rdfs:label "fertilization defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000613 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009566
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000984
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the posterior body axis compared to control." ;
    oboInOwl:hasNarrowSynonym "posterior pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000984" ;
    a owl:Class ;
    rdfs:label "posterior pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000786 .

obo:WBPhenotype_0000985
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the blast cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." ;
    oboInOwl:hasExactSynonym "blast cell physiology variant" ;
    oboInOwl:hasNarrowSynonym "blast cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000985" ;
    a owl:Class ;
    rdfs:label "blast cell physiology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006783
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000986
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the epithelial cell to carry out its normal functions or activities, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "epithelial cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000986" ;
    a owl:Class ;
    rdfs:label "epithelial cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0003672
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000987
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the germ cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "germ cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000987" ;
    a owl:Class ;
    rdfs:label "germ cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006796
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000988
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the gland cell to carry out its normal functions or activities or be able to perceive and respond to signals, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "gland cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000988" ;
    a owl:Class ;
    rdfs:label "gland cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0000989
    obo:IAO_0000115 "Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for a marginal cell to carry out its normal function and activities or be able to perceive and respond to stimuli." ;
    oboInOwl:hasNarrowSynonym "marginal cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000989" ;
    a owl:Class ;
    rdfs:label "marginal cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0003673
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000990
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the muscle cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "muscle cell physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000990" ;
    a owl:Class ;
    rdfs:label "muscle cell physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0003675
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0000991
    obo:IAO_0000115 "OBSOLETE: Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes." ;
    obo:IAO_0100001 obo:WBPhenotype_0002563 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000991" ;
    a owl:Class ;
    rdfs:label "obsolete neuron physiology variant" ;
    owl:deprecated true .

obo:WBPhenotype_0000992
    obo:IAO_0000115 "Failure to execute the characteristic response to high concentrations of sodium chloride solution. C. elegans typically avoids high concentrations of sodium chloride solution." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000992" ;
    a owl:Class ;
    rdfs:label "high sodium chloride concentration osmotic avoidance defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000249, obo:WBPhenotype_0001453 .

obo:WBPhenotype_0000993
    obo:IAO_0000115 "Animals fail to contract the anal depressor muscle." ;
    oboInOwl:hasBroadSynonym "Exp" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000993" ;
    a owl:Class ;
    rdfs:label "anal depressor contraction defect" ;
    rdfs:subClassOf obo:WBPhenotype_0001092 .

obo:WBPhenotype_0000994
    obo:IAO_0000115 "Any variations in the contraction of the enteric muscles that are involved in defecation motor program compared to control." ;
    oboInOwl:hasNarrowSynonym "intestinal contractions abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Emc", "enteric muscle contraction variant" ;
    oboInOwl:id "WBPhenotype:0000994" ;
    a owl:Class ;
    rdfs:label "intestinal contractions variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000210 .

obo:WBPhenotype_0000995
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000995" ;
    a owl:Class ;
    rdfs:comment "WBPhenotype:0000995 an alt_id for \"sodium chloride chemotaxis defective\" (WBPhenotype:0001084) (WS193 OBO and WS200 site) AND has term name \"pos body wall contraction defect\" (dump_phenotype_ace.pl)" ;
    owl:deprecated true .

obo:WBPhenotype_0000996
    obo:IAO_0000115 "Animals exhibit defects in the expulsion of gut contents. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion." ;
    oboInOwl:hasBroadSynonym "Emc", "Exp" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000996" ;
    a owl:Class ;
    rdfs:label "expulsion defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000205 .

obo:WBPhenotype_0000997
    obo:IAO_0000115 "Animals tend to track and stay within low temperature environments." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000997" ;
    a owl:Class ;
    rdfs:label "cryophilic" ;
    rdfs:subClassOf obo:WBPhenotype_0000478 .

obo:WBPhenotype_0000998
    obo:IAO_0000115 "Animals tend to track and stay within high temperature environments." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000998" ;
    a owl:Class ;
    rdfs:label "thermophilic" ;
    rdfs:subClassOf obo:WBPhenotype_0000478 .

obo:WBPhenotype_0000999
    obo:IAO_0000115 "The responses of an animal towards temperature are not influenced by its cultivation temperature." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0000999" ;
    a owl:Class ;
    rdfs:label "athermotactic" ;
    rdfs:subClassOf obo:WBPhenotype_0000478 .

obo:WBPhenotype_0001000
    obo:IAO_0000115 "Any variation in the behavior characteristic during certain developmental stage(s) compared to control." ;
    oboInOwl:hasNarrowSynonym "developmental behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001000" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "developmental behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 .

obo:WBPhenotype_0001001
    obo:IAO_0000115 "Variations in the specific actions or reactions of dauer stage animals in response to external or internal stimuli compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "dauer behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001001" ;
    a owl:Class ;
    rdfs:label "dauer behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000819 .

obo:WBPhenotype_0001002
    obo:IAO_0000115 "Variations in the specific actions or reactions of the head muscles in response to external or internal stimuli compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "head muscle behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001002" ;
    a owl:Class ;
    rdfs:label "head muscle behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000595 .

obo:WBPhenotype_0001003
    obo:IAO_0000115 "Animals die at the L4 stage of the life cycle." ;
    oboInOwl:hasBroadSynonym "Let", "Lvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001003" ;
    a owl:Class ;
    rdfs:label "L4 lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000058 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000038
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001004
    obo:IAO_0000115 "Any variation in the relaxation of pharyngeal muscles after contraction events compared to control." ;
    oboInOwl:hasNarrowSynonym "pharyngeal relaxation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001004" ;
    a owl:Class ;
    rdfs:label "pharyngeal relaxation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000634 .

obo:WBPhenotype_0001005
    obo:IAO_0000115 "Variations in the spontaneous or induced backward crawling locomotion of an animal compared to control." ;
    oboInOwl:hasNarrowSynonym "backward locomotion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001005" ;
    a owl:Class ;
    rdfs:label "backward locomotion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002320 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043057
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001006
    obo:IAO_0000115 "The number of coordinated contraction-relaxation cycles (pumps) exhibited by the pharyngeal muscle deviates from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "pharyngeal pumping rate abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "feeding rate dynamics abnormal", "pumping rate dynamics abnormal" ;
    oboInOwl:id "WBPhenotype:0001006" ;
    a owl:Class ;
    rdfs:label "pharyngeal pumping rate variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000634 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000161
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043050
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001007
    obo:IAO_0000115 "Unclassified abnormality in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb", "Oth" ;
    oboInOwl:hasNarrowSynonym "other abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001007" ;
    a owl:Class ;
    rdfs:label "other abnormality early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001008
    obo:IAO_0000115 "Variations in the progression of a set of interacting or interdependent entities forming the male nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses." ;
    oboInOwl:hasNarrowSynonym "male nervous system development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001008" ;
    a owl:Class ;
    rdfs:label "male nervous system development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000623 .

obo:WBPhenotype_0001009
    obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular developmental stage of the amimal compared to control animals." ;
    oboInOwl:hasNarrowSynonym "developmental pigmentation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001009" ;
    a owl:Class ;
    rdfs:label "developmental pigmentation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000527 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048066
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001010
    obo:IAO_0000115 "Animals appear unusually transparent when compared to control." ;
    oboInOwl:hasBroadSynonym "Clr" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001010" ;
    a owl:Class ;
    rdfs:label "clear" ;
    rdfs:subClassOf obo:WBPhenotype_0000527 .

obo:WBPhenotype_0001011
    obo:IAO_0000115 "Population of unhatched eggs exhibit a complex combination of defects that do not match other class definitions." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001011" ;
    a owl:Class ;
    rdfs:label "complex phenotype early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001007 .

obo:WBPhenotype_0001012
    obo:IAO_0000115 "Animals exhibit variations in their response to disease causing agents, compared to control. Pathogen response includes prevention, damage control and recovery from the infection caused by the attack." ;
    oboInOwl:hasNarrowSynonym "bacterial load variant", "organism pathogen response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001012" ;
    a owl:Class ;
    rdfs:label "organism pathogen response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0098542
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001013
    obo:IAO_0000115 "Animals are more prone to infection compared to control." ;
    oboInOwl:hasBroadSynonym "Esp" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "enhanced susceptibility to pathogens" ;
    oboInOwl:id "WBPhenotype:0001013" ;
    a owl:Class ;
    rdfs:label "pathogen susceptibility increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001012 .

obo:WBPhenotype_0001014
    obo:IAO_0000115 "Animals are less prone to infection compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "pathogen susceptibility decreased" ;
    oboInOwl:id "WBPhenotype:0001014" ;
    a owl:Class ;
    rdfs:label "pathogen resistance increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001012 .

obo:WBPhenotype_0001015
    obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during any development stages compared to control animals." ;
    oboInOwl:hasNarrowSynonym "developmental growth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001015" ;
    a owl:Class ;
    rdfs:label "developmental growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000030 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048589
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001016
    obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the larval stages compared to control animals." ;
    oboInOwl:hasNarrowSynonym "larval growth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001016" ;
    a owl:Class ;
    rdfs:label "larval growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001015 .

obo:WBPhenotype_0001017
    obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the adult stage compared to control animals." ;
    oboInOwl:hasNarrowSynonym "adult growth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001017" ;
    a owl:Class ;
    rdfs:label "adult growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001015 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040007
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000041
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001018
    obo:IAO_0000115 "Any variation that disrupts the cytoplasmic division of a cell during embryonic development compared to control." ;
    oboInOwl:hasBroadSynonym "Cyk" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001018" ;
    a owl:Class ;
    rdfs:label "cytokinesis variant emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000050, obo:WBPhenotype_0002408 .

obo:WBPhenotype_0001019
    obo:IAO_0000115 "Animals arrest during the stage between early and late larval development. In C. elegans, mid larval arrest occurs during the L2 to L3 stages of development." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001019" ;
    a owl:Class ;
    rdfs:label "mid larval arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000059 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0002164
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#ends_during_or_before> ;
                    owl:someValuesFrom obo:WBls_0000027
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#starts_during_or_after> ;
                    owl:someValuesFrom obo:WBls_0000027
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001020
    obo:IAO_0000115 "Animals die during the final stages of embryogenesis. In C. elegans, this lethality refers to death during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation." ;
    oboInOwl:hasBroadSynonym "Emb", "Led" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001020" ;
    a owl:Class ;
    rdfs:label "embryonic lethal late emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000050 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000021
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001021
    obo:IAO_0000115 "Genetically male animals exhibit deviations in the sexual program specific to males. In C. elegans, this often refers to XO animals being transformed into fertile hermaphrodites." ;
    oboInOwl:hasBroadSynonym "Her" ;
    oboInOwl:hasNarrowSynonym "male sexual development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001021" ;
    a owl:Class ;
    rdfs:label "male sexual development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000822 .

obo:WBPhenotype_0001022
    obo:IAO_0000115 "Genetically hermaphrodite animals exhibit deviations in the sexual program specific to hermaphrodites. In C. elegans, this refers to XX animals that develop as males or intersexuals instead of self-fertile hermaphrodites." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite sexual development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001022" ;
    a owl:Class ;
    rdfs:label "hermaphrodite sexual development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000822 .

obo:WBPhenotype_0001023
    obo:IAO_0000115 "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "sexually dimorphic morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001023" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "sexually dimorphic morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000535 .

obo:WBPhenotype_0001024
    obo:IAO_0000115 "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a male in the population, from that observed for control males." ;
    oboInOwl:hasNarrowSynonym "male morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001024" ;
    a owl:Class ;
    rdfs:label "male morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001023 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007850
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001025
    obo:IAO_0000115 "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a hermaphrodite in the population, from that observed for control hermaphrodites." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001025" ;
    a owl:Class ;
    rdfs:label "hermaphrodite morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001023 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007849
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001026
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the membrane enclosed organelle which contains most of the cell's genetic material during the early embryonic stage compared to control animals (Wormatlas)." ;
    oboInOwl:hasBroadSynonym "Emb", "Nmo" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001026" ;
    a owl:Class ;
    rdfs:label "nuclear morphology variation early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001028, obo:WBPhenotype_0001035 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005634
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001027
    obo:IAO_0000115 "Embryos show defects in the placement of the nucleus to a specific location within the cell." ;
    oboInOwl:hasBroadSynonym "Emb", "Npo" ;
    oboInOwl:hasNarrowSynonym "nuclear position abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001027" ;
    a owl:Class ;
    rdfs:label "nuclear position defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000511, obo:WBPhenotype_0001138 .

obo:WBPhenotype_0001028
    obo:IAO_0000115 "The morphological appearance of nuclei differs from control animals." ;
    oboInOwl:hasNarrowSynonym "nuclear appearance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "nuclear morphology variant" ;
    oboInOwl:id "WBPhenotype:0001028" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "nuclear appearance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005634
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001029
    obo:IAO_0000115 "Animals exhibit an uneven distribution of biochromes or any other substances that cause disparate transparency/translucency compared to control animals." ;
    oboInOwl:hasBroadSynonym "Pch" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001029" ;
    a owl:Class ;
    rdfs:label "patchy coloration" ;
    rdfs:subClassOf obo:WBPhenotype_0000527 .

obo:WBPhenotype_0001030
    obo:IAO_0000115 "Any deficiency in the lipid bilayer, the equivalent of the nuclear envelope, that surrounds each pronucleus within gametes and within the early zygote after pronuclear reformation (Wormatlas)." ;
    oboInOwl:hasBroadSynonym "Emb", "Pna" ;
    oboInOwl:hasNarrowSynonym "pronuclear envelope abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001030" ;
    a owl:Class ;
    rdfs:label "pronuclear envelope defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001151 .

obo:WBPhenotype_0001031
    obo:IAO_0000115 "Any variation in the movement/fusion of pronuclei in the fertilized oocyte compared to control. For example, lack of male pronuclear migration, female pronuclear migration variable, sometimes multiple female pronuclei, no or small spindle." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001031" ;
    a owl:Class ;
    rdfs:label "pronuclear migration reduced early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001152 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035046
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001032
    obo:IAO_0000115 "Variations in the specific actions or reactions of a larvae in response to external or internal stimuli compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "larval behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001032" ;
    a owl:Class ;
    rdfs:label "larval behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000819 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030537
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001033
    obo:IAO_0000115 "Any variation in the spatial pattern of proliferation and differentiation in the germ line compared to control. In C. elegans, this refers to an ectopic mass of proliferating germ cells that occupies the proximal adult germ line, a region normally occupied by gametes." ;
    oboInOwl:hasBroadSynonym "Pro" ;
    oboInOwl:hasNarrowSynonym "proximal germ cell proliferation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001033" ;
    a owl:Class ;
    rdfs:label "proximal germ cell proliferation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001215 .

obo:WBPhenotype_0001034
    obo:IAO_0000115 "The morphology of pronuclei and nuclei are defective in the early embryo. In C. elegans, this defect is often characterized by pronuclei and nuclei that are small or missing altogether and are often accompanied by spindle defects." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pronuclear nuclear appearance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001034" ;
    a owl:Class ;
    rdfs:label "pronuclear nuclear appearance defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001374 .

obo:WBPhenotype_0001035
    obo:IAO_0000115 "The size, number and organization of the components of the nuclei in the early embryo deviate from control . In C. elegans, this is characterized by nuclei that are completely missing or are significantly smaller than normal; often accompanied by spindle and cytokinesis defects." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "nuclear appearance number abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "nucleus abnormal emb" ;
    oboInOwl:id "WBPhenotype:0001035" ;
    a owl:Class ;
    rdfs:label "nuclear appearance number defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000770, obo:WBPhenotype_0001138 .

obo:WBPhenotype_0001036
    obo:IAO_0000115 "Any variation that compromises the reproductive ability of an F1 generation animal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001036" ;
    a owl:Class ;
    rdfs:label "sterile F1" ;
    rdfs:subClassOf obo:WBPhenotype_0001037 .

obo:WBPhenotype_0001037
    obo:IAO_0000115 "Any variation that compromises the reproductive ability of the progeny of an animal." ;
    oboInOwl:hasBroadSynonym "Stp" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001037" ;
    a owl:Class ;
    rdfs:label "sterile progeny" ;
    rdfs:subClassOf obo:WBPhenotype_0000069, obo:WBPhenotype_0000688 .

obo:WBPhenotype_0001038
    obo:IAO_0000115 "Germ cells do not exit the mitotic cycle, resulting in a expansion of the unspecialized germ cell population compared to control." ;
    oboInOwl:hasBroadSynonym "Tum" ;
    oboInOwl:hasExactSynonym "tumorous germ line" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001038" ;
    a owl:Class ;
    rdfs:label "tumorous germline" ;
    rdfs:subClassOf obo:WBPhenotype_0000823, obo:WBPhenotype_0002175 .

obo:WBPhenotype_0001039
    obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the embryonic stage compared to control animals." ;
    oboInOwl:hasNarrowSynonym "embryonic growth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001039" ;
    a owl:Class ;
    rdfs:label "embryonic growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001015 .

obo:WBPhenotype_0001040
    obo:IAO_0000115 "Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus, compared to control." ;
    oboInOwl:hasNarrowSynonym "chemosensory response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001040" ;
    a owl:Class ;
    rdfs:label "chemosensory response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000523, obo:WBPhenotype_0001049 .

obo:WBPhenotype_0001041
    obo:IAO_0000115 "Animals exhibit defects in the progression of meiosis which ultimately result in embryonic lethality." ;
    oboInOwl:hasBroadSynonym "Emb", "Mei" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001041" ;
    a owl:Class ;
    rdfs:label "meiosis defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001042
    obo:IAO_0000115 "Neurons show impaired ability in the detection, transmission, coordination or their response to information about an animal's internal and external environments." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001042" ;
    a owl:Class ;
    rdfs:label "neuron function reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001624
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003679
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001043
    obo:IAO_0000115 "Embryos do not enter or take longer to enter first interphase compared to control." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001043" ;
    a owl:Class ;
    rdfs:label "interphase entry defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000740, obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001044
    obo:IAO_0000115 "Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity. In C. elegans, this is often characterized at the two-cell stage." ;
    oboInOwl:hasBroadSynonym "Cpa", "Emb" ;
    oboInOwl:hasNarrowSynonym "cortical dynamics abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001044" ;
    a owl:Class ;
    rdfs:label "cortical dynamics defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000764, obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001045
    obo:IAO_0000115 "Pharyngeal pumping contractions are brief and occur arhythmically in response to stimulus compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001045" ;
    a owl:Class ;
    rdfs:label "sporadic pumping" ;
    rdfs:subClassOf obo:WBPhenotype_0000019 .

obo:WBPhenotype_0001046
    obo:IAO_0000115 "Any variations associated with the characteristic morphology of the pharyngeal muscle such as shape, birefringence etc compared to control." ;
    oboInOwl:hasNarrowSynonym "pharyngeal muscle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001046" ;
    a owl:Class ;
    rdfs:label "pharyngeal muscle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000923 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005451
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001047
    obo:IAO_0000115 "Animals exhibit variations in the movement towards typically attractive water-soluble chemicals compared to control." ;
    oboInOwl:hasNarrowSynonym "aqueous positive chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "water soluble chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001047" ;
    a owl:Class ;
    rdfs:label "aqueous positive chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000635, obo:WBPhenotype_0001443 .

obo:WBPhenotype_0001048
    obo:IAO_0000115 "Animals exhibit variations in the chemosensory response to volatile organic compounds compared to control." ;
    oboInOwl:hasBroadSynonym "Odr" ;
    oboInOwl:hasNarrowSynonym "odorant chemosensory response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "volatile chemosensory response abnormal" ;
    oboInOwl:id "WBPhenotype:0001048" ;
    a owl:Class ;
    rdfs:label "odorant chemosensory response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001040 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042048
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001049
    obo:IAO_0000115 "Variations in behavior that is dependent upon the sensation of chemicals, compared to control." ;
    oboInOwl:hasNarrowSynonym "chemosensory behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001049" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "chemosensory behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007635
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001050
    obo:IAO_0000115 "Animals exhibit variations in any of a series of events in which an organism receives a sensory chemical stimulus, converts it to a molecular signal, and recognizes and characterizes the signal, compared to control." ;
    oboInOwl:hasNarrowSynonym "chemosensation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001050" ;
    a owl:Class ;
    rdfs:label "chemosensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001049 .

obo:WBPhenotype_0001051
    obo:IAO_0000115 "Animals exhibit variations in the characteristic movement towards typically attractive cations compared to control." ;
    oboInOwl:hasNarrowSynonym "cation positive chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001051" ;
    a owl:Class ;
    rdfs:label "cation positive chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001047 .

obo:WBPhenotype_0001052
    obo:IAO_0000115 "Animals exhibit variations in the characteristic movement towards typically attractive anions compared to control." ;
    oboInOwl:hasNarrowSynonym "anion positive chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001052" ;
    a owl:Class ;
    rdfs:label "anion positive chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001047 .

obo:WBPhenotype_0001053
    obo:IAO_0000115 "Animals exhibit variations in the characteristic movement towards cyclic nucleotides compared to control." ;
    oboInOwl:hasNarrowSynonym "cyclic nucleotide positive chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001053" ;
    a owl:Class ;
    rdfs:label "cyclic nucleotide positive chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001047 .

obo:WBPhenotype_0001054
    obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to cGMP. In C. elegans, this is characterized by the failure to move towards cGMP." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001054" ;
    a owl:Class ;
    rdfs:label "cGMP chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001464 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_27682
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001055
    obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to bromide. In C. elegans, this is characterized by the failure to move towards bromide." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001055" ;
    a owl:Class ;
    rdfs:label "bromide chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001439, obo:WBPhenotype_0001457 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_15858
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001056
    obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to iodide. In C. elegans, this is characterized by the failure to move towards iodide." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001056" ;
    a owl:Class ;
    rdfs:label "iodide chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001439, obo:WBPhenotype_0001459 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_16382
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001057
    obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to lithium. In C. elegans, this is characterized by the failure to move towards lithium." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001057" ;
    a owl:Class ;
    rdfs:label "lithium chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001440 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_30145
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001058
    obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to potassium. In C. elegans, this is characterized by the failure of the animals to move towards potassium." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001058" ;
    a owl:Class ;
    rdfs:label "potassium chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001440 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_26216
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001059
    obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to magnesium. In C. elegans, this is characterized by the failure to move towards magnesium." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001059" ;
    a owl:Class ;
    rdfs:label "magnesium chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001440 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_25107
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001060
    obo:IAO_0000115 "In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWC compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "AWC volatile chemotaxis defective" ;
    oboInOwl:id "WBPhenotype:0001060" ;
    a owl:Class ;
    rdfs:label "AWC odorant chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438 .

obo:WBPhenotype_0001061
    obo:IAO_0000115 "In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWA compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "AWA volatile chemotaxis defective" ;
    oboInOwl:id "WBPhenotype:0001061" ;
    a owl:Class ;
    rdfs:label "AWA odorant chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438 .

obo:WBPhenotype_0001062
    obo:IAO_0000115 "In C. elegans, movement and elongation stop nearly simultaneously soon after the twofold stage of elongation. However, mutant embryos twitch at the one-and-a-half-fold stage of elongation, like control animals, and move as well as control animals at the two- fold stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001062" ;
    a owl:Class ;
    rdfs:label "late paralysis arrested elongation two fold" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 .

obo:WBPhenotype_0001063
    obo:IAO_0000115 "Fluctuation pattern between inactive, active, and egg-laying states is atypical, based on the analysis of the distribution of the log intervals of egg-laying events compared to control." ;
    oboInOwl:hasNarrowSynonym "egg laying phases abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001063" ;
    a owl:Class ;
    rdfs:label "egg laying phases variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000272 .

obo:WBPhenotype_0001064
    obo:IAO_0000115 "Animals display uncharacteristically long periods during which they do not lay eggs compared to control, usually based on the analysis of the distribution of the log intervals of egg-laying events. In C. elegans, long inactive phases can be observed in HSN-ablated and serotonin-deficient animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001064" ;
    a owl:Class ;
    rdfs:label "inactive phase long" ;
    rdfs:subClassOf obo:WBPhenotype_0000006, obo:WBPhenotype_0001066 .

obo:WBPhenotype_0001065
    obo:IAO_0000115 "Fewer egg-laying events occur within the active phase of egg laying, based on the analysis of the distribution of the log intervals of egg-laying events, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001065" ;
    a owl:Class ;
    rdfs:label "fewer egg laying events during active" ;
    rdfs:subClassOf obo:WBPhenotype_0000006, obo:WBPhenotype_0001067 .

obo:WBPhenotype_0001066
    obo:IAO_0000115 "The period during which the animal is less likely to lay eggs is not typical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ;
    oboInOwl:hasNarrowSynonym "inactive phase abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001066" ;
    a owl:Class ;
    rdfs:label "inactive phase variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001063 .

obo:WBPhenotype_0001067
    obo:IAO_0000115 "The active phase of egg-laying, the period during which animals are more likely to display multiple egg-laying events, is atypical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ;
    oboInOwl:hasNarrowSynonym "active phase abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001067" ;
    a owl:Class ;
    rdfs:label "active phase variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001063 .

obo:WBPhenotype_0001068
    obo:IAO_0000115 "Animals are not induced to lay eggs in reponse to exogenous serotonin. Serotonin stimulates egg-laying in C. elegans." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001068" ;
    a owl:Class ;
    rdfs:label "egg laying serotonin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001629 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001552
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_28790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001069
    obo:IAO_0000115 "More eggs are laid during the active phase compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001069" ;
    a owl:Class ;
    rdfs:label "increased egg laying events during active" ;
    rdfs:subClassOf obo:WBPhenotype_0001067 .

obo:WBPhenotype_0001070
    obo:IAO_0000115 "The period during which a worm usually does not lay eggs is short compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001070" ;
    a owl:Class ;
    rdfs:label "inactive phase short" ;
    rdfs:subClassOf obo:WBPhenotype_0001066 .

obo:WBPhenotype_0001071
    obo:IAO_0000115 "Activation of the active phase of egg laying is defective, leading to an abnormally long inactive phase, based on the analysis of the distribution of the log intervals of egg-laying events." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001071" ;
    a owl:Class ;
    rdfs:label "active phase switch defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001064 .

obo:WBPhenotype_0001072
    obo:IAO_0000115 "Any variation in the state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to a food stimulus, compared to control." ;
    oboInOwl:hasNarrowSynonym "response to food abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001072" ;
    a owl:Class ;
    rdfs:label "response to food variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0032094
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001073
    obo:IAO_0000115 "Animals exhibit variations in egg-laying behavior in response to food compared to control. In C. elegans, well-fed animals lay more eggs compared with starved animals." ;
    oboInOwl:hasNarrowSynonym "egg laying response to food abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001073" ;
    a owl:Class ;
    rdfs:label "egg laying response to food variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000640, obo:WBPhenotype_0001072 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001457
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_33290
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001074
    obo:IAO_0000115 "The vulval muscle does not respond to serotonin in the same manner as control animals. This phenotype is often assayed by imaging of calcium transients in response to serotonin." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001074" ;
    a owl:Class ;
    rdfs:label "vulval muscle unresponsive to serotonin" ;
    rdfs:subClassOf obo:WBPhenotype_0001068, obo:WBPhenotype_0001076 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000488
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_28790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005821
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001075
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the vulva muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "vulval muscle physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001075" ;
    a owl:Class ;
    rdfs:label "vulval muscle physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000613 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005821
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001076
    obo:IAO_0000115 "Variations in the chemical reactions and pathways involved in the maintenance of an internal equilibrium within the vulval muscles compared to control." ;
    oboInOwl:hasNarrowSynonym "vulval muscle homeostasis metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001076" ;
    a owl:Class ;
    rdfs:label "vulval muscle homeostasis metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001075 .

obo:WBPhenotype_0001077
    obo:IAO_0000115 "Karyomeres in AB or P1 often accompanied by weak/thin wobbly spindle." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001077" ;
    a owl:Class ;
    rdfs:label "chromosome segregation variant karyomeres early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000773, obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001078
    obo:IAO_0000115 "Cytokinesis is abnormal in the first or second stages of cell division." ;
    oboInOwl:hasBroadSynonym "Cyk", "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001078" ;
    a owl:Class ;
    rdfs:label "cytokinesis defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001018, obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001079
    obo:IAO_0000115 "Cytoplasmic movements are atypical." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001079" ;
    a owl:Class ;
    rdfs:label "cytoplasmic dynamics defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000360, obo:WBPhenotype_0000769 .

obo:WBPhenotype_0001080
    obo:IAO_0000115 "Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001080" ;
    a owl:Class ;
    rdfs:label "excessive blebbing early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001079 .

obo:WBPhenotype_0001081
    obo:IAO_0000115 "Morphology of the cytoplasm differs from control animals." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001081" ;
    a owl:Class ;
    rdfs:label "cytoplasmic morphology defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000769 .

obo:WBPhenotype_0001082
    obo:IAO_0000115 "Abnormally large granules are observed in the cytoplasm of P0." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001082" ;
    a owl:Class ;
    rdfs:label "large cytoplasmic granules early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001081 .

obo:WBPhenotype_0001083
    obo:IAO_0000115 "Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001083" ;
    a owl:Class ;
    rdfs:label "multiple cytoplasmic cavities early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001081 .

obo:WBPhenotype_0001084
    obo:IAO_0000115 "Failure to execute characteristic response to sodium chloride compared to control. In C. elegans, animals move towards attractive concentrations of sodium chloride." ;
    oboInOwl:hasExactSynonym "NaCl chemotaxis defective" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001084" ;
    a owl:Class ;
    rdfs:label "sodium chloride chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001462 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_26710
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001085
    obo:IAO_0000115 "Failure to execute characteristic response to butanone compared to control. In C. elegans, animals move towards typically attractive concentrations of butanone." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001085" ;
    a owl:Class ;
    rdfs:label "butanone chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001469 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_22951
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001086
    obo:IAO_0000115 "Failure to execute characteristic response to trimethylthiazole compared to control. In C. elegans, animals move towards typically attractive concentrations of trimethylthiazole." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001086" ;
    a owl:Class ;
    rdfs:label "trimethylthiazole chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001475 .

obo:WBPhenotype_0001087
    obo:IAO_0000115 "Failure to execute characteristic response to acetone compared to control. In C. elegans, animals move towards typically attractive concentrations of acetone." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001087" ;
    a owl:Class ;
    rdfs:label "acetone chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001465 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_15347
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001088
    obo:IAO_0000115 "Failure to execute characteristic response to pentanol compared to control. In C. elegans, animals move towards typically attractive concentrations of pentanol." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001088" ;
    a owl:Class ;
    rdfs:label "pentanol chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001473 .

obo:WBPhenotype_0001089
    obo:IAO_0000115 "Failure to execute characteristic response to hexanol compared to control. In C. elegans, animals move towards typically attractive concentrations of hexanol." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001089" ;
    a owl:Class ;
    rdfs:label "hexanol chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001471 .

obo:WBPhenotype_0001090
    obo:IAO_0000115 "Animals are not able to survive at temperatures above standard cultivation temperatures to the same extent as control animals." ;
    oboInOwl:hasNarrowSynonym "intrinsic thermotolerance reduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001090" ;
    a owl:Class ;
    rdfs:label "thermotolerance reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000146 .

obo:WBPhenotype_0001091
    obo:IAO_0000115 "Animals exhibit variations in the elimination of fecal matter during the larval stage compared to control animals." ;
    oboInOwl:hasNarrowSynonym "larval defecation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001091" ;
    a owl:Class ;
    rdfs:label "larval defecation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000650 .

obo:WBPhenotype_0001092
    obo:IAO_0000115 "Animals fail to expel fecal matter during the larval stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001092" ;
    a owl:Class ;
    rdfs:label "larval defecation defect" ;
    rdfs:subClassOf obo:WBPhenotype_0001091 .

obo:WBPhenotype_0001093
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the intestine to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "intestinal physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001093" ;
    a owl:Class ;
    rdfs:label "intestinal physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000606 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005772
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001094
    obo:IAO_0000115 "OBSOLETE. Organismal response to NaCl differs from control animals." ;
    oboInOwl:consider obo:WBPhenotype_0000523 ;
    oboInOwl:hasNarrowSynonym "NaCl response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001094" ;
    a owl:Class ;
    rdfs:label "obsolete NaCl response variant" ;
    owl:deprecated true .

obo:WBPhenotype_0001095
    obo:IAO_0000115 "Animals respond to sodium chloride at a lower concentration or a shorter exposure compared to control animals. In C. elegans, this is often assayed through generation time and progeny number." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001095" ;
    a owl:Class ;
    rdfs:label "organism high sodium chloride hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000876 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_26710
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001096
    obo:IAO_0000115 "Large protrusion at the normal position of the vulva, as seen in C. elegans lin-12 null animals." ;
    oboInOwl:hasNarrowSynonym "ventral protrusion" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001096" ;
    a owl:Class ;
    rdfs:label "protrusion at vulval region" ;
    rdfs:subClassOf obo:WBPhenotype_0000695 .

obo:WBPhenotype_0001097
    obo:IAO_0000115 "Unspecialized male germ cells (spermatocytes) prematurely acquire the specialized properties of functional sperm." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001097" ;
    a owl:Class ;
    rdfs:label "premature spermatocyte germ cell differentiation" ;
    rdfs:subClassOf obo:WBPhenotype_0000670 .

obo:WBPhenotype_0001098
    obo:IAO_0000115 "Animals lack the passage connecting the posterior intestine to the rectal valve." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001098" ;
    a owl:Class ;
    rdfs:comment "WBbt:0005773." ;
    rdfs:label "no rectum" ;
    rdfs:subClassOf obo:WBPhenotype_0000910 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005773
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001099
    obo:IAO_0000115 "The extreme anterior part of the body appears distorted, usually due to uncharacteristic winding." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001099" ;
    a owl:Class ;
    rdfs:label "nose twisted" ;
    rdfs:subClassOf obo:WBPhenotype_0000321 .

obo:WBPhenotype_0001100
    obo:IAO_0000115 "Animal dies prior to the gastrulation stage of embryogenesis." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001100" ;
    a owl:Class ;
    rdfs:label "early embryonic lethal" ;
    rdfs:subClassOf obo:WBPhenotype_0000050 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001101
    obo:IAO_0000115 "Characteristic response to drugs with respect to egg-laying behavior varies compared to control." ;
    oboInOwl:hasNarrowSynonym "egg laying response to drug abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001101" ;
    a owl:Class ;
    rdfs:label "egg laying response to drug variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0000640 .

obo:WBPhenotype_0001102
    obo:IAO_0000115 "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a mitotic cell cycle." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001102" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "mitotic spindle defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000759 .

obo:WBPhenotype_0001103
    obo:IAO_0000115 "Early embryos lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001103" ;
    a owl:Class ;
    rdfs:label "spindle absent early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001102, obo:WBPhenotype_0002418 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002000
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0005819
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001104
    obo:IAO_0000115 "No mitotic spindle is seen in P0." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001104" ;
    a owl:Class ;
    rdfs:label "P0 spindle absent early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001103 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002000
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0005819
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004422
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001105
    obo:IAO_0000115 "Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "P0 spindle position phenotype" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001105" ;
    a owl:Class ;
    rdfs:label "P0 spindle position abnormal" ;
    rdfs:subClassOf obo:WBPhenotype_0000762 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000140
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0072686
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000050 ;
                                owl:someValuesFrom obo:WBbt_0004422
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001106
    obo:IAO_0000115 "The orientation of the spindle is aberrant in either the AB or the P1 cell." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001106" ;
    a owl:Class ;
    rdfs:label "spindle orientation variant AB or P1 early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000760 .

obo:WBPhenotype_0001107
    obo:IAO_0000115 "Rotation of the embryonic spindle is aberrant." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001107" ;
    a owl:Class ;
    rdfs:label "spindle rotation defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001102, obo:WBPhenotype_0002417 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001599
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005819
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001108
    obo:IAO_0000115 "P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001108" ;
    a owl:Class ;
    rdfs:label "P0 spindle rotation failure early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001107 .

obo:WBPhenotype_0001109
    obo:IAO_0000115 "P0 spindle rotates late in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001109" ;
    a owl:Class ;
    rdfs:label "P0 spindle rotation delayed early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0001107 .

obo:WBPhenotype_0001110
    obo:IAO_0000115 "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "aster abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001110" ;
    a owl:Class ;
    rdfs:label "aster defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002419 .

obo:WBPhenotype_0001111
    obo:IAO_0000115 "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the AB cell." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "aster AB abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001111" ;
    a owl:Class ;
    rdfs:label "aster AB defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001110 .

obo:WBPhenotype_0001112
    obo:IAO_0000115 "The morphology of the AB aster resembles that of the P1 aster in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001112" ;
    a owl:Class ;
    rdfs:label "aster AB resembles P1 aster early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001111 .

obo:WBPhenotype_0001113
    obo:IAO_0000115 "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the P1 cell." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "P1 aster abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001113" ;
    a owl:Class ;
    rdfs:label "P1 aster defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001110 .

obo:WBPhenotype_0001114
    obo:IAO_0000115 "The progression of biochemical and morphological processes that occur during successive replication or nuclear replication events is disrupted during the early embryonic stage." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001114" ;
    a owl:Class ;
    rdfs:label "cell cycle defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000740, obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001115
    obo:IAO_0000115 "Cell cycle timing is abnormal during the first four cell divisions." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001115" ;
    a owl:Class ;
    rdfs:label "cell cycle timing defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001114 .

obo:WBPhenotype_0001116
    obo:IAO_0000115 "Absolute cell cycle timing during the first four cell divisions is aberrant." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "absolute cell cycle timing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001116" ;
    a owl:Class ;
    rdfs:label "absolute cell cycle timing defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001115 .

obo:WBPhenotype_0001117
    obo:IAO_0000115 "Cell-cell contacts are abnormal in the early embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001117" ;
    a owl:Class ;
    rdfs:label "cell cell contacts abnormal early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002404 .

obo:WBPhenotype_0001118
    obo:IAO_0000115 "Cell position is abnormal in the early embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001118" ;
    a owl:Class ;
    rdfs:label "cell position defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002402 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000140
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CL_0000000
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001119
    obo:IAO_0000115 "Embryos take longer to divide during the first and second cell divisions." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001119" ;
    a owl:Class ;
    rdfs:label "cell cycle slow early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0001116 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051726
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001120
    obo:IAO_0000115 "Relative cell cycle timing during the first four cell divisions is aberrant." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "relative cell cycle timing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001120" ;
    a owl:Class ;
    rdfs:label "relative cell cycle timing defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001115 .

obo:WBPhenotype_0001121
    obo:IAO_0000115 "Asynchrony of the second division is exaggerated and P1 divides more slowly than normal." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001121" ;
    a owl:Class ;
    rdfs:label "exaggerated asynchrony early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001120 .

obo:WBPhenotype_0001122
    obo:IAO_0000115 "P1 divides before AB." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001122" ;
    a owl:Class ;
    rdfs:label "reversed asynchrony early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001120 .

obo:WBPhenotype_0001123
    obo:IAO_0000115 "AB and P1 divide synchronously." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001123" ;
    a owl:Class ;
    rdfs:label "synchronous second division early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001120 .

obo:WBPhenotype_0001124
    obo:IAO_0000115 "EMS divides at the same time that ABa and ABp divide." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001124" ;
    a owl:Class ;
    rdfs:label "ABa ABp EMS synchronous division early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001120 .

obo:WBPhenotype_0001125
    obo:IAO_0000115 "P2 and EMS divide synchronously." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001125" ;
    a owl:Class ;
    rdfs:label "P2 EMS synchronous division early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001120 .

obo:WBPhenotype_0001126
    obo:IAO_0000115 "Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "cell cell contacts abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001126" ;
    a owl:Class ;
    rdfs:label "cell cell contacts abnormal in four cell embryo" ;
    rdfs:subClassOf obo:WBPhenotype_0001117 .

obo:WBPhenotype_0001127
    obo:IAO_0000115 "The EMS blastomere fails to extend anteriorly and make extensive contact (hug) with the ABa blastomere." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001127" ;
    a owl:Class ;
    rdfs:label "EMS anterior extension fails early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001118 .

obo:WBPhenotype_0001128
    obo:IAO_0000115 "EMS extends too far anteriorly at the four cell stage." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001128" ;
    a owl:Class ;
    rdfs:label "EMS anterior extension extreme early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001118 .

obo:WBPhenotype_0001129
    obo:IAO_0000115 "Embryos exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001129" ;
    a owl:Class ;
    rdfs:label "cleavage furrow defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001078, obo:WBPhenotype_0002410 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001453
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0032154
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001130
    obo:IAO_0000115 "Cells of the embryo attempt to divide but fail to form two daughter cells." ;
    oboInOwl:hasBroadSynonym "Cyk", "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001130" ;
    a owl:Class ;
    rdfs:label "cytokinesis fails early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001078, obo:WBPhenotype_0002391 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000910
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001131
    obo:IAO_0000115 "Once formed, the mitotic furrow can \"slide\"laterally." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001131" ;
    a owl:Class ;
    rdfs:label "loose mitotic furrow early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001129 .

obo:WBPhenotype_0001132
    obo:IAO_0000115 "One or more extra cleavage furrows are seen in one or more cells of a one-cell to four-cell embryo" ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001132" ;
    a owl:Class ;
    rdfs:label "extra cleavage furrow early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001129 .

obo:WBPhenotype_0001133
    obo:IAO_0000115 "The cell division axis is not normal." ;
    oboInOwl:hasNarrowSynonym "division axis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001133" ;
    a owl:Class ;
    rdfs:label "division axis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 .

obo:WBPhenotype_0001134
    obo:IAO_0000115 "ABa or ABp divide in the wrong orientation." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "Aba ABp division axis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001134" ;
    a owl:Class ;
    rdfs:label "Aba ABp division axis defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001133 .

obo:WBPhenotype_0001135
    obo:IAO_0000115 "Animals exhibit defects in the form, structure or composition of any of its parts during the early embryonic stage." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001135" ;
    a owl:Class ;
    rdfs:label "embryonic morphology defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001136 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001136
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any of its parts during any developmental stage ranging from zygote formation to hatching compared to control." ;
    oboInOwl:hasNarrowSynonym "embryonic morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001136" ;
    a owl:Class ;
    rdfs:label "embryonic morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000037 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000003
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001137
    obo:IAO_0000115 "Embryos are produced that are less than fifty percent of the size of control embryos." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001137" ;
    a owl:Class ;
    rdfs:label "embryos small early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001135 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000587
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001138
    obo:IAO_0000115 "Nucleus is abnormal in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "nucleus abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001138" ;
    a owl:Class ;
    rdfs:label "nucleus defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000764 .

obo:WBPhenotype_0001139
    obo:IAO_0000115 "Nuclear envelope does not reassemble properly." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "nuclear reassembly defective early emb" ;
    oboInOwl:id "WBPhenotype:0001139" ;
    a owl:Class ;
    rdfs:label "nuclear envelope assembly variant early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001138, obo:WBPhenotype_0002037 .

obo:WBPhenotype_0001140
    obo:IAO_0000115 "Any variation in the normal orderly movement of neurons from one site to another compared to control." ;
    oboInOwl:hasNarrowSynonym "neuron migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001140" ;
    a owl:Class ;
    rdfs:label "neuron migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000594, obo:WBPhenotype_0000816 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0001764
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001141
    obo:IAO_0000115 "After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001141" ;
    a owl:Class ;
    rdfs:label "nucleus reforms cell division remnant early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001027 .

obo:WBPhenotype_0001142
    obo:IAO_0000115 "Nuclear number is abnormal in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001142" ;
    a owl:Class ;
    rdfs:label "nuclear number defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001035, obo:WBPhenotype_0001894 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005634
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001143
    obo:IAO_0000115 "Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb", "Mul" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "karyomeres", "multiple nuclei in early embryo emb" ;
    oboInOwl:id "WBPhenotype:0001143" ;
    a owl:Class ;
    rdfs:label "multiple nuclei early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000746, obo:WBPhenotype_0001142, obo:WBPhenotype_0002413 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0005634
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001144
    obo:IAO_0000115 "Defects are either seen in the number or size of the polar bodies in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001144" ;
    a owl:Class ;
    rdfs:label "polar body number size early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001147 .

obo:WBPhenotype_0001145
    obo:IAO_0000115 "Polar body number is abnormal in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "polar body number abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001145" ;
    a owl:Class ;
    rdfs:label "polar body number defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001144 .

obo:WBPhenotype_0001146
    obo:IAO_0000115 "Polar body size is abnormal in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "polar body size abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001146" ;
    a owl:Class ;
    rdfs:label "polar body size defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001144 .

obo:WBPhenotype_0001147
    obo:IAO_0000115 "Polar bodies are abnormal in the inviable one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "polar body abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001147" ;
    a owl:Class ;
    rdfs:label "polar body defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001148
    obo:IAO_0000115 "Polar body is reabsorbed in the one- to four-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001148" ;
    a owl:Class ;
    rdfs:label "polar body reabsorbed early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000777 .

obo:WBPhenotype_0001149
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0001148 ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001149" ;
    a owl:Class ;
    rdfs:label "obsolete polar body reabsorbed first early emb" ;
    owl:deprecated true .

obo:WBPhenotype_0001150
    obo:IAO_0000115 "A polar body is reabsorbed in either the one cell- or the two-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001150" ;
    a owl:Class ;
    rdfs:label "polar body reabsorbed one two early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001148 .

obo:WBPhenotype_0001151
    obo:IAO_0000115 "Pronucleus is abnormal in the inviable embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pronucleus centrosomes abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001151" ;
    a owl:Class ;
    rdfs:label "pronucleus centrosomes defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001034 .

obo:WBPhenotype_0001152
    obo:IAO_0000115 "Pronucleus migration is abnormal in the inviable embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pronuclear migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001152" ;
    a owl:Class ;
    rdfs:label "pronuclear migration defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001151 .

obo:WBPhenotype_0001153
    obo:IAO_0000115 "Neither of the pronuclei migrate and they never meet." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001153" ;
    a owl:Class ;
    rdfs:label "pronuclear migration failure early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001152 .

obo:WBPhenotype_0001154
    obo:IAO_0000115 "Instead of the maternal pronucleus migrating to the posterior end of the one-cell embryo, the paternal pronucleus migrates to meet the maternal pronucleus in the anterior end." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001154" ;
    a owl:Class ;
    rdfs:label "paternal pronucleus migrates early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001152 .

obo:WBPhenotype_0001155
    obo:IAO_0000115 "The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001155" ;
    a owl:Class ;
    rdfs:label "pronuclei meet centrally early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001152 .

obo:WBPhenotype_0001156
    obo:IAO_0000115 "Maternal or paternal pronucleus is either too small or too large." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pronuclear size abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001156" ;
    a owl:Class ;
    rdfs:label "pronuclear size defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001159 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000117
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0045120
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001157
    obo:IAO_0000115 "Pronuclear breakdown is atypical in the inviable embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pronuclear breakdown abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001157" ;
    a owl:Class ;
    rdfs:label "pronuclear breakdown defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001151 .

obo:WBPhenotype_0001158
    obo:IAO_0000115 "Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001158" ;
    a owl:Class ;
    rdfs:label "pronuclear breakdown asynchronous early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001157 .

obo:WBPhenotype_0001159
    obo:IAO_0000115 "Pronucleus morphology is atypical in the inviable embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pronuclear morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001159" ;
    a owl:Class ;
    rdfs:label "pronuclear morphology defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001151 .

obo:WBPhenotype_0001160
    obo:IAO_0000115 "Morphology of the pronuclear envelope is atypical in the inviable embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pronuclear envelope morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001160" ;
    a owl:Class ;
    rdfs:label "pronuclear envelope morphology defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001159 .

obo:WBPhenotype_0001161
    obo:IAO_0000115 "Maternal pronucleus has a blurry appearance. The nuclear envelope does not have a crisp circular shape." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001161" ;
    a owl:Class ;
    rdfs:label "maternal pronucleus indistinct early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001160 .

obo:WBPhenotype_0001162
    obo:IAO_0000115 "There are more than two pronuclei in the inviable embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pronuclear number abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001162" ;
    a owl:Class ;
    rdfs:label "pronuclear number defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001151 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0045120
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001163
    obo:IAO_0000115 "Either the maternal or paternal pronucleus is absent." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001163" ;
    a owl:Class ;
    rdfs:label "pronucleus formation failure early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001162 .

obo:WBPhenotype_0001164
    obo:IAO_0000115 "There is either more than one maternal or paternal pronucleus in the inviable embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001164" ;
    a owl:Class ;
    rdfs:label "excess pronucleus early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001162, obo:WBPhenotype_0002175 .

obo:WBPhenotype_0001165
    obo:IAO_0000115 "One-cell embryos have two or more maternal pronuclei." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001165" ;
    a owl:Class ;
    rdfs:label "excess maternal pronucleus early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001164 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0001939
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000004
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001166
    obo:IAO_0000115 "More than one paternal pronucleus is present in the inviable one-cell embryo or there is a defect in centrosome structure." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "excess paternal pronucleus abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001166" ;
    a owl:Class ;
    rdfs:label "excess paternal pronucleus variant centrosome early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001164 .

obo:WBPhenotype_0001167
    obo:IAO_0000115 "Pseudocleavage is atypical in the inviable one-cell embryo." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "pseudocleavage abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001167" ;
    a owl:Class ;
    rdfs:label "pseudocleavage defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001168
    obo:IAO_0000115 "No pseudocleavage is observed before or during pronuclear migration." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "no pseudocleavage" ;
    oboInOwl:id "WBPhenotype:0001168" ;
    a owl:Class ;
    rdfs:label "pseudocleavage absent early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001167 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030590
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001169
    obo:IAO_0000115 "Embryos have more pronounced pseudocleavage than normal." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001169" ;
    a owl:Class ;
    rdfs:label "pseudocleavage exaggerated early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001167 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000586
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030588
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001170
    obo:IAO_0000115 "Injected worm stops producing embryos 48 hours after RNAi injection and contains no live/developing embryos at this time." ;
    oboInOwl:hasBroadSynonym "Ste" ;
    oboInOwl:hasNarrowSynonym "P0 sterile" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001170" ;
    a owl:Class ;
    rdfs:label "sterile F0 48 hours post injection" ;
    rdfs:subClassOf obo:WBPhenotype_0000689 .

obo:WBPhenotype_0001171
    obo:IAO_0000115 "The duration of viability in the adult phase of the life-cycle is less than that of control animals." ;
    oboInOwl:hasBroadSynonym "Age" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "life span reduced", "longevity decreased" ;
    oboInOwl:id "WBPhenotype:0001171" ;
    a owl:Class ;
    rdfs:label "shortened life span" ;
    rdfs:subClassOf obo:WBPhenotype_0000039 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001604
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001172
    obo:IAO_0000115 "Developmentally regulated termination of a cell or cell group does not occur as in control animals." ;
    oboInOwl:hasNarrowSynonym "programmed cell death abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001172" ;
    a owl:Class ;
    rdfs:label "programmed cell death variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000729 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0012501
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001173
    obo:IAO_0000115 "Animals exhibit variations in the specific activation or halting of processes within a cell that occur through necrosis or programmed cell death pathways different from apoptosis, so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death, compared to control." ;
    oboInOwl:hasNarrowSynonym "non apoptotic cell death abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001173" ;
    a owl:Class ;
    rdfs:label "non apoptotic cell death variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001172 .

obo:WBPhenotype_0001174
    obo:IAO_0000115 "Chromosomes fail to segregate away from their homolog, resulting in gametes with no or extra copies of the chromosome." ;
    oboInOwl:hasNarrowSynonym "chromosome disjunction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001174" ;
    a owl:Class ;
    rdfs:label "chromosome disjunction defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001499, obo:WBPhenotype_0001882, obo:WBPhenotype_0002012 .

obo:WBPhenotype_0001175
    obo:IAO_0000115 "Higher numbers of male progeny occur in the population compared to control populations. In C. elegans, the high incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an increase in X chromosome nondisjunction." ;
    oboInOwl:hasBroadSynonym "Him" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "high frequency X chromosome nondisjunction" ;
    oboInOwl:id "WBPhenotype:0001175" ;
    a owl:Class ;
    rdfs:label "high incidence male progeny" ;
    rdfs:subClassOf obo:WBPhenotype_0001664 .

obo:WBPhenotype_0001176
    obo:IAO_0000115 "One-cell embryos have an altered shape." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasNarrowSynonym "one cell shape abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001176" ;
    a owl:Class ;
    rdfs:label "one cell shape defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001135 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000052
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000006
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001177
    obo:IAO_0000115 "Embryos rupture when placed on a 2% agar pad and covered with a coverslip." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001177" ;
    a owl:Class ;
    rdfs:label "embryo osmotic pressure sensitive early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001178 .

obo:WBPhenotype_0001178
    obo:IAO_0000115 "The structure of the egg is impaired, flawed or no longer intact." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001178" ;
    a owl:Class ;
    rdfs:label "egg integrity defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002075 .

obo:WBPhenotype_0001179
    obo:IAO_0000115 "OBSOLETE. Phenotypic examination of worms did not reveal an obvious abnormality compared with control animals." ;
    oboInOwl:hasNarrowSynonym "No abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "WT" ;
    oboInOwl:id "WBPhenotype:0001179" ;
    a owl:Class ;
    rdfs:comment "The phenotype ontology was restructured such that \"Abnormal\" is now the root term.  The term \"Abnormal\" with a \"Not\" qualifier is a suggested replacement for this term.", "This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype." ;
    rdfs:label "obsolete No variantity scored" ;
    owl:deprecated true .

obo:WBPhenotype_0001180
    obo:IAO_0000115 "Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001180" ;
    a owl:Class ;
    rdfs:label "accumulated germline cell corpses" ;
    rdfs:subClassOf obo:WBPhenotype_0000241 .

obo:WBPhenotype_0001181
    obo:IAO_0000115 "Animals exhibit an increase in the quantity of non-germ line cells that have undergone programmed cell death but have not been engulfed." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001181" ;
    a owl:Class ;
    rdfs:label "accumulated somatic cell corpses" ;
    rdfs:subClassOf obo:WBPhenotype_0000241 .

obo:WBPhenotype_0001182
    obo:IAO_0000115 "Animals exhibit variations in the amount of fat or lipids present in the organism compared to control animals." ;
    oboInOwl:hasNarrowSynonym "fat content abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid content abnormal", "lipid content variant" ;
    oboInOwl:id "WBPhenotype:0001182" ;
    a owl:Class ;
    rdfs:label "fat content variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000725 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_18059
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001183
    obo:IAO_0000115 "Animals exhibit less fat or lipid than observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid content reduced" ;
    oboInOwl:id "WBPhenotype:0001183" ;
    a owl:Class ;
    rdfs:label "fat content reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001182 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_18059
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001184
    obo:IAO_0000115 "Animals exhibit a greater amount of fat or lipids than observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid content increased" ;
    oboInOwl:id "WBPhenotype:0001184" ;
    a owl:Class ;
    rdfs:label "fat content increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001182 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_18059
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001185
    obo:IAO_0000115 "The developmental progression of an early embryo over time, from its formation to its mature structure is delayed compared to control." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001185" ;
    a owl:Class ;
    rdfs:label "embryonic developmental delay early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000848, obo:WBPhenotype_0001100 .

obo:WBPhenotype_0001186
    obo:IAO_0000115 "Embryos are either delayed or arrested at pronuclear contact." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001186" ;
    a owl:Class ;
    rdfs:label "embryo delayed at pronuclear contact early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001185 .

obo:WBPhenotype_0001187
    obo:IAO_0000115 "EMS divides before P2." ;
    oboInOwl:hasBroadSynonym "Emb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001187" ;
    a owl:Class ;
    rdfs:label "division EMS before P2 early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001120 .

obo:WBPhenotype_0001188
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of radial arrangement of actin within the pharyngeal muscle compared to control animals." ;
    oboInOwl:hasNarrowSynonym "radial filament structure abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001188" ;
    a owl:Class ;
    rdfs:label "radial filament structure variant pharynx" ;
    rdfs:subClassOf obo:WBPhenotype_0001046 .

obo:WBPhenotype_0001189
    obo:IAO_0000115 "Any variation in the cell junctions of the pharyngeal muscle at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control." ;
    oboInOwl:hasNarrowSynonym "adherens junctions abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001189" ;
    a owl:Class ;
    rdfs:label "adherens junctions variant pharyngeal muscle" ;
    rdfs:subClassOf obo:WBPhenotype_0001046, obo:WBPhenotype_0001745 .

obo:WBPhenotype_0001190
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the pharynx to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "pharyngeal physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001190" ;
    a owl:Class ;
    rdfs:label "pharyngeal physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000606 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0003681
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001191
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for muscles in the pharynx to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "pharyngeal muscle physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001191" ;
    a owl:Class ;
    rdfs:label "pharyngeal muscle physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001190 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005451
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001192
    obo:IAO_0000115 "Any variation in the series of molecular signals in which a pharyngeal cell uses calcium ions to convert an extracellular signal into a response, compared to control." ;
    oboInOwl:hasNarrowSynonym "calcium signaling pharynx abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001192" ;
    a owl:Class ;
    rdfs:label "calcium signaling in pharynx variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001191, obo:WBPhenotype_0002170 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0019722
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0003681
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001193
    obo:IAO_0000115 "Electropharyngeograms do not show a similar pattern as control animals. C. elegans animals show a repeating regular pattern in which each pump is associated with an excitatory depolarizing wave, often punctuated by brief negative spikes, followed by a plateau phase, and ending with an inhibitory hyperpolarizing wave." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001193" ;
    a owl:Class ;
    rdfs:label "disorganized pharyngeal EPG" ;
    rdfs:subClassOf obo:WBPhenotype_0000980 .

obo:WBPhenotype_0001194
    obo:IAO_0000115 "Animals have one or more extra neurons, which are present in places they are normally not found, when compared to the number and location of these neurons in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001194" ;
    a owl:Class ;
    rdfs:label "extra and ectopic neuron" ;
    rdfs:subClassOf obo:WBPhenotype_0001303 .

obo:WBPhenotype_0001195
    obo:IAO_0000115 "Rhythmic calcium increases in the pharynx are observed less often than in control animals. In C. elegans, rhythmic increases in intracellular calcium are often observed using a transgenically expressed cameleon, a ratiometric calcium indicator." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001195" ;
    a owl:Class ;
    rdfs:label "generation calcium signal defective pharynx" ;
    rdfs:subClassOf obo:WBPhenotype_0001192 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050848
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBbt_0003681
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001196
    obo:IAO_0000115 "Calcium spikes lack synchrony in the musculature of the corpus and the terminal bulb as seen in control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001196" ;
    a owl:Class ;
    rdfs:label "synchronization calcium signal defective pharynx" ;
    rdfs:subClassOf obo:WBPhenotype_0001192 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000688
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0019722
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBbt_0003681
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001197
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic gonad to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "somatic gonad physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001197" ;
    a owl:Class ;
    rdfs:label "somatic gonad physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000613 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005785
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001198
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic sheath system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "somatic sheath physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001198" ;
    a owl:Class ;
    rdfs:label "somatic sheath physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001197 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005828
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001199
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the contraction of a thin continuous tube surrounding the proximal portions of the ovary and covering the maturing oocytes to the near portion of the distal gonad arm, compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "gonad sheath contractions abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001199" ;
    a owl:Class ;
    rdfs:label "gonad sheath contractions variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001198 .

obo:WBPhenotype_0001200
    obo:IAO_0000115 "Basal contraction rate and or peak contraction rate of the gonadal sheath is reduced relative to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001200" ;
    a owl:Class ;
    rdfs:label "gonad sheath contraction rate reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001199 .

obo:WBPhenotype_0001201
    obo:IAO_0000115 "Animals lack the stereotyped muscle contractions that result in the opening of anus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001201" ;
    a owl:Class ;
    rdfs:label "no expulsion defecation" ;
    rdfs:subClassOf obo:WBPhenotype_0000391 .

obo:WBPhenotype_0001202
    obo:IAO_0000115 "Animals respond to nicotine at lower concentrations or shorter exposure compared to control. Nicotine is a cholinergic agonist." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001202" ;
    a owl:Class ;
    rdfs:label "nicotine hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001573, obo:WBPhenotype_0001579 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_18723
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001203
    obo:IAO_0000115 "Animals fail to respond to the concentration of nicotine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001203" ;
    a owl:Class ;
    rdfs:label "nicotine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001573, obo:WBPhenotype_0001578 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_18723
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001204
    obo:IAO_0000115 "Animals fail to respond to the concentration of muscimol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001204" ;
    a owl:Class ;
    rdfs:label "muscimol resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0002047 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_7035
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001205
    obo:IAO_0000115 "Animals respond to muscimol at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001205" ;
    a owl:Class ;
    rdfs:label "muscimol hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0002047 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_7035
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001206
    obo:IAO_0000115 "Variations in the process by which an organism travels from one location to another compared to control." ;
    oboInOwl:hasNarrowSynonym "movement abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001206" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 .

obo:WBPhenotype_0001207
    obo:IAO_0000115 "Any variation in a series of protein mediated signals that help relay information within the cell, and thereby affecting changes in the functioning of the cell, compared to control." ;
    oboInOwl:hasNarrowSynonym "protein signaling abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001207" ;
    a owl:Class ;
    rdfs:label "protein signaling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0001208
    obo:IAO_0000115 "Animals show reduced susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control." ;
    oboInOwl:hasBroadSynonym "Rde" ;
    oboInOwl:hasExactSynonym "RNAi deficient" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001208" ;
    a owl:Class ;
    rdfs:label "RNAi resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000513
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016246
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001209
    obo:IAO_0000115 "Apparently normal sinusoidal movement, but appear to have poor traction on the agar surface of a culture plate." ;
    oboInOwl:hasBroadSynonym "Skd" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001209" ;
    a owl:Class ;
    rdfs:label "skiddy" ;
    rdfs:subClassOf obo:WBPhenotype_0001701 .

obo:WBPhenotype_0001210
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process taking place in extracellular spaces within or associated with the organism, from that observed for control animals." ;
    oboInOwl:hasExactSynonym "pericellular component physiology abnormal", "pericellular component physiology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001210" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "pericellular component physiology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000519 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005732
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001211
    obo:IAO_0000115 "The physical strength or function of the cuticle varies from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "cuticle integrity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001211" ;
    a owl:Class ;
    rdfs:label "cuticle integrity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001678 .

obo:WBPhenotype_0001212
    obo:IAO_0000115 "The strength of the cuticle is less robust than that observed for control animals. In C. elegans the strength of the cuticle is often assayed by it's ability to protect the animal from exposure to bleach or other compounds." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001212" ;
    a owl:Class ;
    rdfs:label "cuticle fragile" ;
    rdfs:subClassOf obo:WBPhenotype_0002640 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001362
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005755
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001213
    obo:IAO_0000115 "Animals exhibit a decrease in any parameter used to measure locomotion compared to control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001288" ;
    oboInOwl:hasExactSynonym "movement reduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001213" ;
    a owl:Class ;
    rdfs:label "locomotion reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000641 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007626
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040011
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001214
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0001496 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001214" ;
    a owl:Class ;
    rdfs:label "obsolete metaphase to anaphase transition fails" ;
    owl:deprecated true .

obo:WBPhenotype_0001215
    obo:IAO_0000115 "Variations in the mitotic expansion of germ cell populations or in the appearance of nuclei during development in the premeiotic region of the germline compared to control." ;
    oboInOwl:hasNarrowSynonym "germ cell mitosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001215" ;
    a owl:Class ;
    rdfs:label "germ cell mitosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000823 .

obo:WBPhenotype_0001216
    obo:IAO_0000115 "Oocyte chromosomes arrest in metaphase of meiosis I without transitioning to anaphase or producing polar bodies." ;
    oboInOwl:hasBroadSynonym "Mat" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001216" ;
    a owl:Class ;
    rdfs:label "meiosis metaphase to anaphase transition block" ;
    rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0001496 .

obo:WBPhenotype_0001217
    obo:IAO_0000115 "Germ line cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001217" ;
    a owl:Class ;
    rdfs:label "germ cell mitosis metaphase to anaphase transition block" ;
    rdfs:subClassOf obo:WBPhenotype_0001215, obo:WBPhenotype_0001497 .

obo:WBPhenotype_0001218
    obo:IAO_0000115 "Animals exhibit variations in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations." ;
    oboInOwl:hasNarrowSynonym "cell death sexually dimorphic abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001218" ;
    a owl:Class ;
    rdfs:label "cell death sexually dimorphic variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBPhenotype_0001219
    obo:IAO_0000115 "Animals exhibit a decrease in the rate or extent of programmed cell death and thus an increase in cell survival, as it pertains to a sex-specific feature, compared to control populations." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001219" ;
    a owl:Class ;
    rdfs:label "cell survival sexually dimorphic increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001218 .

obo:WBPhenotype_0001220
    obo:IAO_0000115 "Animals exhibit in increase in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001220" ;
    a owl:Class ;
    rdfs:label "cell death sexually dimorphic increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001218 .

obo:WBPhenotype_0001221
    obo:IAO_0000115 "Animal fails to exhibit characteristic response after a nose-on collision with an object compared to control. In C. elegans, this is usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal." ;
    oboInOwl:hasBroadSynonym "Not" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001221" ;
    a owl:Class ;
    rdfs:label "nose touch defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000456, obo:WBPhenotype_0004026 .

obo:WBPhenotype_0001222
    obo:IAO_0000115 "Animals exhibit an increase in frequency of transposition events (DNA movement to different positions within the genome of a single cell) causing an accumulation of lesions within the genome, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Mut", "mutator" ;
    oboInOwl:id "WBPhenotype:0001222" ;
    a owl:Class ;
    rdfs:label "transposon mutator" ;
    rdfs:subClassOf obo:WBPhenotype_0000228 .

obo:WBPhenotype_0001223
    obo:IAO_0000115 "Animals show reduced susceptibility to gene silencing in the germline triggered by double stranded RNA (RNAi), compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001223" ;
    a owl:Class ;
    rdfs:label "germline RNAi resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001208 .

obo:WBPhenotype_0001224
    obo:IAO_0000115 "Any variation in the processes that govern the extension of axons compared to control." ;
    oboInOwl:hasNarrowSynonym "axon outgrowth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "axon migration variant" ;
    oboInOwl:id "WBPhenotype:0001224" ;
    a owl:Class ;
    rdfs:label "axon outgrowth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000572 .

obo:WBPhenotype_0001225
    obo:IAO_0000115 "Animals are missing the interfacial hypodermal cell (socket cell) of the phasmid sensillum pore." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Psa" ;
    oboInOwl:id "WBPhenotype:0001225" ;
    a owl:Class ;
    rdfs:label "phasmid socket absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001527 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0008410
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001226
    obo:IAO_0000115 "Animals display variations in the structure, organization or path of the part of the axon that forms a bridge between body regions, compared to that in control animals." ;
    oboInOwl:hasNarrowSynonym "commissure abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001226" ;
    a owl:Class ;
    rdfs:label "commissure variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000181 .

obo:WBPhenotype_0001227
    obo:IAO_0000115 "Animals are missing any one of its commissures, an axon tract that connects one body part to another." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001227" ;
    a owl:Class ;
    rdfs:label "commissure absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001226 .

obo:WBPhenotype_0001228
    obo:IAO_0000115 "Animals lack the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001228" ;
    a owl:Class ;
    rdfs:label "alae absent" ;
    rdfs:subClassOf obo:WBPhenotype_0000202 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007832
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001229
    obo:IAO_0000115 "The orderly movement of neurons along the anterior axis of the animal is abolished, misdirected or incomplete compared to control." ;
    oboInOwl:hasNarrowSynonym "abnormal anterior neuron migration" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001229" ;
    a owl:Class ;
    rdfs:label "anterior neuron migration defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001140 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001632
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:GO_0001764
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001230
    obo:IAO_0000115 "The orderly movement of cells along the anterior axis of the animal is abolished, misdirected or incomplete compared to control." ;
    oboInOwl:hasNarrowSynonym "abnormal anterior cell migration" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001230" ;
    a owl:Class ;
    rdfs:label "anterior cell migration defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000594 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001632
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016477
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001231
    obo:IAO_0000115 "The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is increased compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ift accelerated" ;
    oboInOwl:id "WBPhenotype:0001231" ;
    a owl:Class ;
    rdfs:label "intraflagellar transport accelerated" ;
    rdfs:subClassOf obo:WBPhenotype_0000853 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042073
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001232
    obo:IAO_0000115 "Animals exhibit variations in the response to the addition of serotonin compared to that observed in control animals. Serotonin is a monoamine neurotransmitter." ;
    oboInOwl:hasNarrowSynonym "serotonin response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001232" ;
    a owl:Class ;
    rdfs:label "serotonin response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_28790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001233
    obo:IAO_0000115 "Animals exhibit variations in the pattern of a chemical nuclear stain which is commonly used in fixed specimens and produces a bright blue label, compared to control. DAPI (4'-6-Diamidino-2-phenylindole) forms fluorescent complexes with natural double-stranded DNA (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "DAPI staining abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001233" ;
    a owl:Class ;
    rdfs:label "DAPI staining variant" ;
    rdfs:subClassOf obo:WBPhenotype_0010002 .

obo:WBPhenotype_0001234
    obo:IAO_0000115 "Failure to execute the characteristic response to nonanone compared to control. In C. elegans, nonanone is a repellant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001234" ;
    a owl:Class ;
    rdfs:label "nonanone chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001448, obo:WBPhenotype_0001456 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050919
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_25579
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001235
    obo:IAO_0000115 "Any variation in the orientation of the physical partitioning and separation of a cell into daughter cells compared to control." ;
    oboInOwl:hasNarrowSynonym "cell division polarity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001235" ;
    a owl:Class ;
    rdfs:label "cell division polarity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001769
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051301
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001236
    obo:IAO_0000115 "Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001236" ;
    a owl:Class ;
    rdfs:label "transgene expression increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000962 .

obo:WBPhenotype_0001237
    obo:IAO_0000115 "Any perturbation that causes an increase in the frequency of axon outgrowth compared to control. As a result, an excess number of axonal projections are generated." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001237" ;
    a owl:Class ;
    rdfs:label "excess axon outgrowth" ;
    rdfs:subClassOf obo:WBPhenotype_0000629, obo:WBPhenotype_0001224 .

obo:WBPhenotype_0001238
    obo:IAO_0000115 "Any variation in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva." ;
    oboInOwl:hasNarrowSynonym "male mating latency abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001238" ;
    a owl:Class ;
    rdfs:label "male mating latency variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000648 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001005
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007618
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0007850
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001239
    obo:IAO_0000115 "Any increase in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001239" ;
    a owl:Class ;
    rdfs:label "mating latency increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001238, obo:WBPhenotype_0001414 .

obo:WBPhenotype_0001240
    obo:IAO_0000115 "Variations in the processes leading to the specialization of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control." ;
    oboInOwl:hasNarrowSynonym "male tail sensory ray differentiation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001240" ;
    a owl:Class ;
    rdfs:label "male tail sensory ray differentiation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000199 .

obo:WBPhenotype_0001241
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000297 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001241" ;
    a owl:Class ;
    rdfs:label "obsolete ray fusion" ;
    owl:deprecated true .

obo:WBPhenotype_0001242
    obo:IAO_0000115 "The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is lower compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001242" ;
    a owl:Class ;
    rdfs:label "intraflagellar transport slow" ;
    rdfs:subClassOf obo:WBPhenotype_0000854 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042073
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001243
    obo:IAO_0000115 "The bidirectional transport of molecules (cargo) along axonemal microtubules is reduced compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001243" ;
    a owl:Class ;
    rdfs:label "intraflagellar transport distance short" ;
    rdfs:subClassOf obo:WBPhenotype_0001247 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000375
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042073
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001244
    obo:IAO_0000115 "Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is completely abolished." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001244" ;
    a owl:Class ;
    rdfs:label "intraflagellar transport absent" ;
    rdfs:subClassOf obo:WBPhenotype_0000854 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042073
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001245
    obo:IAO_0000115 "The bidirectional transport of molecules along the middle segment of axonemal microtubules of the cilia is absent." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001245" ;
    a owl:Class ;
    rdfs:label "no transport middle segment cilia" ;
    rdfs:subClassOf obo:WBPhenotype_0001243 .

obo:WBPhenotype_0001246
    obo:IAO_0000115 "The bidirectional transport of molecules along the distal segment of axonemal microtubules of the cilia is absent." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001246" ;
    a owl:Class ;
    rdfs:label "no transport distal segment cilia" ;
    rdfs:subClassOf obo:WBPhenotype_0001243 .

obo:WBPhenotype_0001247
    obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons is disrupted." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001247" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "anterograde transport defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000854, obo:WBPhenotype_0001477 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048490
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001248
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the microtuble-based projections that in control animals invaginate individually into the sheath cell of the neuronal sensillum rather than projecting through the socket cell to the outside. In C. elegans, the cilia of each wing cell has its own unique shape and as they are not exposed to the outside, they do not typically take up dyes." ;
    oboInOwl:hasNarrowSynonym "wing cilia morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "AWC cilia morphology abnormal" ;
    oboInOwl:id "WBPhenotype:0001248" ;
    a owl:Class ;
    rdfs:label "wing cilia morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000615 .

obo:WBPhenotype_0001249
    obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the dendritic projections of the amphid sensory neurons that traverse the sensillum pore to connect with the outside of the animal, compared to that observed in control animals. In C. elegans, amphid channel cilia morphology is frequently assayed by dye-filling experiments using FITC, DiI or DiO." ;
    oboInOwl:hasNarrowSynonym "amphid channel cilia morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001249" ;
    a owl:Class ;
    rdfs:label "amphid channel cilia morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000615 .

obo:WBPhenotype_0001250
    obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the microtuble-based fibrillar core, axoneme, of the cilia of the neurons that project through the sensillum pore to the outside of the animal, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "amphid channel axoneme morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001250" ;
    a owl:Class ;
    rdfs:label "amphid channel axoneme morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000262, obo:WBPhenotype_0001249 .

obo:WBPhenotype_0001251
    obo:IAO_0000115 "The microtuble-based fibrillar-bundles of the amphid sensory cilia are reduced in length compared to those in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001251" ;
    a owl:Class ;
    rdfs:label "amphid channel axoneme short" ;
    rdfs:subClassOf obo:WBPhenotype_0001250 .

obo:WBPhenotype_0001252
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the microtubule-based fibrillar section, axoneme, of the cilia of the flat sheet-like cells associated with sensory function, from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "wing cilia axoneme morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001252" ;
    a owl:Class ;
    rdfs:label "wing cilia axoneme morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001248 .

obo:WBPhenotype_0001253
    obo:IAO_0000115 "The microtuble-based fibrillar-bundle, axoneme, of the wing cell cilia are reduced in length and do not extend into the sheath cell as far as they do in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001253" ;
    a owl:Class ;
    rdfs:label "wing cilia axoneme short" ;
    rdfs:subClassOf obo:WBPhenotype_0001252 .

obo:WBPhenotype_0001254
    obo:IAO_0000115 "The dendritic processes that normally extend through the amphid sensillum pore to the outside are truncated and have swollen ends as opposed to the extended and finger-like tips of channel cilia in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001254" ;
    a owl:Class ;
    rdfs:label "amphid channel cilia bulbous" ;
    rdfs:subClassOf obo:WBPhenotype_0001249 .

obo:WBPhenotype_0001255
    obo:IAO_0000115 "Animals exhibit wing cell sensory cilia that are truncated and swollen unlike that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001255" ;
    a owl:Class ;
    rdfs:label "wing cilia bulbous" ;
    rdfs:subClassOf obo:WBPhenotype_0001248 .

obo:WBPhenotype_0001256
    obo:IAO_0000115 "Variations in the aggregation of molecules at the site of DNA strand breakage or damage compared to control." ;
    oboInOwl:hasNarrowSynonym "DNA damage induced focus formation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "DNA repair induced focus formation" ;
    oboInOwl:id "WBPhenotype:0001256" ;
    a owl:Class ;
    rdfs:label "DNA damage induced focus formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000739 .

obo:WBPhenotype_0001257
    obo:IAO_0000115 "Variations in the generation of foci that mark sites of aberrant bonding of molecules to the DNA strand, compared to control." ;
    oboInOwl:hasNarrowSynonym "cross link induced focus formation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001257" ;
    a owl:Class ;
    rdfs:label "cross link induced focus formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001256 .

obo:WBPhenotype_0001258
    obo:IAO_0000115 "Animals show increased susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Eri" ;
    oboInOwl:id "WBPhenotype:0001258" ;
    a owl:Class ;
    rdfs:label "RNAi enhanced" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002017
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016246
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001259
    obo:IAO_0000115 "Hermaphrodites exhibit a reduction in the production of new individuals owing to defects in gamete competence and/or function compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001259" ;
    a owl:Class ;
    rdfs:label "hermaphrodite fertility reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000806 .

obo:WBPhenotype_0001260
    obo:IAO_0000115 "Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control." ;
    oboInOwl:hasNarrowSynonym "oocyte morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001260" ;
    a owl:Class ;
    rdfs:label "oocyte morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000900 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006797
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001261
    obo:IAO_0000115 "Animals show deficiencies in chroma resulting in increased translucency." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001261" ;
    a owl:Class ;
    rdfs:label "pale" ;
    rdfs:subClassOf obo:WBPhenotype_0000527 .

obo:WBPhenotype_0001262
    obo:IAO_0000115 "The developmental progression of the egg-laying organ of female and hermaphrodite nematodes is halted prior to the formation of the mature structure." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001262" ;
    a owl:Class ;
    rdfs:label "vulval development incomplete" ;
    rdfs:subClassOf obo:WBPhenotype_0000699 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040025
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001263
    obo:IAO_0000115 "The morphological appearance of peroxisomes is variant compared to control animals." ;
    oboInOwl:hasNarrowSynonym "peroxisome morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001263" ;
    a owl:Class ;
    rdfs:label "peroxisome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005777
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001264
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the peroxisome to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "peroxisome physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001264" ;
    a owl:Class ;
    rdfs:label "peroxisome physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:GO_0005777
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001265
    obo:IAO_0000115 "The anterior portion of the animal exhibits variations in its movement compared to control." ;
    oboInOwl:hasNarrowSynonym "Erratic head vibration", "head movement abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001265" ;
    a owl:Class ;
    rdfs:label "head movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001699 .

obo:WBPhenotype_0001266
    obo:IAO_0000115 "Any variation in triggering of the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control." ;
    oboInOwl:hasNarrowSynonym "genetic pathway activation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001266" ;
    a owl:Class ;
    rdfs:label "genetic pathway activation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000074 .

obo:WBPhenotype_0001267
    obo:IAO_0000115 "Any variation in the frequency of gonad sheath contractions triggered by internal or external stimuli compared to control." ;
    oboInOwl:hasNarrowSynonym "induced contraction rate abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001267" ;
    a owl:Class ;
    rdfs:label "induced contraction rate variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001199 .

obo:WBPhenotype_0001268
    obo:IAO_0000115 "Animals exhibit variations in the extent of activation of programmed cell death, compared to control." ;
    oboInOwl:hasNarrowSynonym "induced cell death abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001268" ;
    a owl:Class ;
    rdfs:label "induced cell death variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000729 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043068
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001269
    obo:IAO_0000115 "Animals exhibit variations in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ;
    oboInOwl:hasNarrowSynonym "pathogen induced cell death abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001269" ;
    a owl:Class ;
    rdfs:label "pathogen induced cell death variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001268 .

obo:WBPhenotype_0001270
    obo:IAO_0000115 "Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001270" ;
    a owl:Class ;
    rdfs:label "pathogen induced cell death reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001269 .

obo:WBPhenotype_0001271
    obo:IAO_0000115 "Animals are more prone to lethality as a result of infection compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001271" ;
    a owl:Class ;
    rdfs:label "pathogen induced death increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001013 .

obo:WBPhenotype_0001272
    obo:IAO_0000115 "Vulval precursor cells inappropriately adopt fates that are normally restricted to other vulval precursor cells compared to control." ;
    oboInOwl:hasExactSynonym "vulval precursor cell induction abnormal" ;
    oboInOwl:hasNarrowSynonym "vulval cell induction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001272" ;
    a owl:Class ;
    rdfs:label "vulval cell induction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000220 .

obo:WBPhenotype_0001273
    obo:IAO_0000115 "Any variation in the state or activity of an organism (in terms of movement, gene expression, etc.) in response to heat (high temperatures above the optimal temperature for that organism), compared to control." ;
    oboInOwl:hasNarrowSynonym "organism heat response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001273" ;
    a owl:Class ;
    rdfs:label "organism heat response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009408
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001274
    obo:IAO_0000115 "Animals respond to heat at a lower temperature or a shorter exposure time compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001274" ;
    a owl:Class ;
    rdfs:label "organism heat hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001273 .

obo:WBPhenotype_0001275
    obo:IAO_0000115 "Any variation that increases the magnitude of a signal generated by a set of gene interactions in a given pathway, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001275" ;
    a owl:Class ;
    rdfs:label "increased genetic pathway signal" ;
    rdfs:subClassOf obo:WBPhenotype_0000074 .

obo:WBPhenotype_0001276
    obo:IAO_0000115 "Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001276" ;
    a owl:Class ;
    rdfs:label "ectopic expression transgene" ;
    rdfs:subClassOf obo:WBPhenotype_0000961 .

obo:WBPhenotype_0001277
    obo:IAO_0000115 "XX animals are transformed into males or pseudomales ." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Tra" ;
    oboInOwl:id "WBPhenotype:0001277" ;
    a owl:Class ;
    rdfs:label "transformer" ;
    rdfs:subClassOf obo:WBPhenotype_0001572 .

obo:WBPhenotype_0001278
    obo:IAO_0000115 "Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001278" ;
    a owl:Class ;
    rdfs:label "transgene expression reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000962 .

obo:WBPhenotype_0001279
    obo:IAO_0000115 "Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the male, that has been introduced into the organism compared to its expression in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001279" ;
    a owl:Class ;
    rdfs:label "transgene expression reduced male" ;
    rdfs:subClassOf obo:WBPhenotype_0001278 .

obo:WBPhenotype_0001280
    obo:IAO_0000115 "Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the hermaphrodite, that has been introduced into the organism compared to its expression in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001280" ;
    a owl:Class ;
    rdfs:label "transgene expression reduced hermaphrodite" ;
    rdfs:subClassOf obo:WBPhenotype_0001278 .

obo:WBPhenotype_0001281
    obo:IAO_0000115 "Pharynx becomes clogged with food. In C. elegans, this is often a result of pharyngeal pumping defects." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001281" ;
    a owl:Class ;
    rdfs:label "stuffed pharynx" ;
    rdfs:subClassOf obo:WBPhenotype_0000634, obo:WBPhenotype_0000778 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001836
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003681
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001282
    obo:IAO_0000115 "Variations in the chemical reactions and pathways of the mitochondria compared to control." ;
    oboInOwl:hasNarrowSynonym "mitochondrial metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001282" ;
    a owl:Class ;
    rdfs:label "mitochondrial metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001283 .

obo:WBPhenotype_0001283
    obo:IAO_0000115 "Variations in the chemical reactions and pathways of an organelle compared to control." ;
    oboInOwl:hasNarrowSynonym "organelle metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001283" ;
    a owl:Class ;
    rdfs:label "organelle metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000585 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008152
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:GO_0043226
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001284
    obo:IAO_0000115 "Animals contain a lower level of coenzyme Q, an oil-soluble vitamin-like substance present in most eukaryotic cells, primarily in the mitochondria, compared to control. It is a component of the electron transport chain and participates in aerobic cellular respiration." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001284" ;
    a owl:Class ;
    rdfs:label "coenzyme Q depleted" ;
    rdfs:subClassOf obo:WBPhenotype_0000026, obo:WBPhenotype_0001282 .

obo:WBPhenotype_0001285
    obo:IAO_0000115 "Pharyngeal pumping is not influenced by treatment with specific compounds (eg: serotonin) in the same manner as control animals." ;
    oboInOwl:hasNarrowSynonym "induced pharyngeal pumping abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001285" ;
    a owl:Class ;
    rdfs:label "induced pharyngeal pumping variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 .

obo:WBPhenotype_0001286
    obo:IAO_0000115 "Exposure to food does not reduce pharyngeal pumping to the same extent as observed in control animals." ;
    oboInOwl:hasNarrowSynonym "food suppressed pumping abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001286" ;
    a owl:Class ;
    rdfs:label "food suppressed pumping variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001072, obo:WBPhenotype_0001287 .

obo:WBPhenotype_0001287
    obo:IAO_0000115 "Animals do not exhibit a decrease in pumping rate when treated with specific compounds (such as pheromones) as is observed for control animals." ;
    oboInOwl:hasNarrowSynonym "suppressed pharyngeal pumping abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001287" ;
    a owl:Class ;
    rdfs:label "suppressed pharyngeal pumping defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 .

obo:WBPhenotype_0001288
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0001213 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001288" ;
    a owl:Class ;
    rdfs:comment "is alternative id for \"locomotion reduced\" (WBPhenotype:0001213); may have originally had term name \"movement reduced\"" ;
    owl:deprecated true .

obo:WBPhenotype_0001289
    obo:IAO_0000115 "Animals fail to respond to the concentration of acetylcholinesterase inhibitor that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001289" ;
    a owl:Class ;
    rdfs:label "acetylcholinesterase inhibitor resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001290 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_38462
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001290
    obo:IAO_0000115 "Animals exhibit variations in their response to a specific acetylcholinesterase inhibitor compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "acetylcholinesterase inhibitor response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001290" ;
    a owl:Class ;
    rdfs:label "acetylcholinesterase inhibitor response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_38462
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001291
    obo:IAO_0000115 "Animals exhibit variations in actions and responses that occurs predominantly, or only, in individuals that are part of a group, from that observed for animals in a control group." ;
    oboInOwl:hasNarrowSynonym "social behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001291" ;
    a owl:Class ;
    rdfs:label "social behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035176
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001292
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the body wall muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body wall muscle physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001292" ;
    a owl:Class ;
    rdfs:label "body wall muscle physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000611 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006804
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001293
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the larva to carry out its normal metabolic functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasExactSynonym "larval physiology abnormal", "larval physiology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001293" ;
    a owl:Class ;
    rdfs:label "larval physiology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000576 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000023
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001294
    obo:IAO_0000115 "The most anterior portion of the animal is not aligned with the axis of the body." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001294" ;
    a owl:Class ;
    rdfs:label "head bent" ;
    rdfs:subClassOf obo:WBPhenotype_0000071 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000617
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005739
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001295
    obo:IAO_0000115 "Any portion of the animal, between the head and the tail, appears distorted, usually due to uncharacteristic winding." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001295" ;
    a owl:Class ;
    rdfs:label "body twisted" ;
    rdfs:subClassOf obo:WBPhenotype_0000072 .

obo:WBPhenotype_0001296
    obo:IAO_0000115 "Animals fail to respond to the concentration of lannate that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasExactSynonym "methomyl resistant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001296" ;
    a owl:Class ;
    rdfs:label "lannate resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001289 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_6835
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001297
    obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the male tail over time, from its formation to the mature structure, compared to control." ;
    oboInOwl:hasNarrowSynonym "male tail development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001297" ;
    a owl:Class ;
    rdfs:label "male tail development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000805 .

obo:WBPhenotype_0001298
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the more posterior portion of the intestine, just anterior to the sphincter valve, which is subject to squeezing by the somatal-intestinal muscles compared to control animals (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "hindgut morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001298" ;
    a owl:Class ;
    rdfs:label "hindgut morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000710 .

obo:WBPhenotype_0001299
    obo:IAO_0000115 "Any variation that alters the physical partitioning and separation of a cell into daughter cells in male animals compared to control." ;
    oboInOwl:hasNarrowSynonym "cell division abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001299" ;
    a owl:Class ;
    rdfs:label "cell division variant male" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 .

obo:WBPhenotype_0001300
    obo:IAO_0000115 "Any variation in the composition or structure of the contents within a germ cell, excluding the plasma membrane and nucleus, compared to control. Germ cells include sperm, oocytes, and their precursors." ;
    oboInOwl:hasNarrowSynonym "germ cell cytoplasmic morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001300" ;
    a owl:Class ;
    rdfs:label "germ cell cytoplasmic morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000900 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0005737
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000050 ;
                                owl:someValuesFrom obo:WBbt_0006796
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001301
    obo:IAO_0000115 "Localization or structural appearance of P-granules is altered compared to control. P-granules are cytoplasmic structures associated with germ nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell precursors, throughout the life cycle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001301" ;
    a owl:Class ;
    rdfs:label "P granule abnormal" ;
    rdfs:subClassOf obo:WBPhenotype_0001300 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043186
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001302
    obo:IAO_0000115 "The restricted localization of P granules to germ cells or germ cell precursors is altered compared to control." ;
    oboInOwl:hasNarrowSynonym "P granule localization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "germ granule localization defective" ;
    oboInOwl:id "WBPhenotype:0001302" ;
    a owl:Class ;
    rdfs:label "P granule localization defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001301 .

obo:WBPhenotype_0001303
    obo:IAO_0000115 "Animals have one or more extra cells of a particular type, which are present in places they are normally not found, when compared to the number and location of these cells in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001303" ;
    a owl:Class ;
    rdfs:label "extra and ectopic cell" ;
    rdfs:subClassOf obo:WBPhenotype_0002175, obo:WBPhenotype_0002493 .

obo:WBPhenotype_0001304
    obo:IAO_0000115 "The terminal portion of the intestine exhibits structural defects such as scarring or blockage." ;
    oboInOwl:hasBroadSynonym "Scar" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001304" ;
    a owl:Class ;
    rdfs:label "hindgut damaged" ;
    rdfs:subClassOf obo:WBPhenotype_0001298 .

obo:WBPhenotype_0001305
    obo:IAO_0000115 "Any variation in the form or composition of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating." ;
    oboInOwl:hasNarrowSynonym "hook morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001305" ;
    a owl:Class ;
    rdfs:label "hook morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000070 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0008425
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001306
    obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the male reproductive system compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ;
    oboInOwl:hasNarrowSynonym "male reproductive system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001306" ;
    a owl:Class ;
    rdfs:label "male reproductive system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000605 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005747
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0007850
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001307
    obo:IAO_0000115 "The maximum ventral and dorsal flex of the animal is reduced compared to that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001307" ;
    a owl:Class ;
    rdfs:label "reduced body bend" ;
    rdfs:subClassOf obo:WBPhenotype_0001703 .

obo:WBPhenotype_0001308
    obo:IAO_0000115 "The contraction and relaxation movements of the pharyngeal muscle that mediate feeding is not as robust as compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001308" ;
    a owl:Class ;
    rdfs:label "weak pumping" ;
    rdfs:subClassOf obo:WBPhenotype_0000634 .

obo:WBPhenotype_0001309
    obo:IAO_0000115 "Animals exhibit a decrease in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000003" ;
    oboInOwl:hasExactSynonym "amplitude of body bends decreased", "flat locomotion path", "flattened locomotion path" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001309" ;
    a owl:Class ;
    rdfs:label "amplitude of sinusoidal movement decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0004022 .

obo:WBPhenotype_0001310
    obo:IAO_0000115 "The placement of neuronal cells, as a whole or of a specific class of neuron in the animal, deviates from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "neuron positioning abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001310" ;
    a owl:Class ;
    rdfs:label "neuron positioning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000604 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000140
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003679
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001311
    obo:IAO_0000115 "Variations that result in a decrease in protein expression in hermaphrodites compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001311" ;
    a owl:Class ;
    rdfs:label "protein expression reduced hermaphrodite" ;
    rdfs:subClassOf obo:WBPhenotype_0000120 .

obo:WBPhenotype_0001312
    obo:IAO_0000115 "The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "neuron number abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001312" ;
    a owl:Class ;
    rdfs:label "neuron number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000604 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003679
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001313
    obo:IAO_0000115 "Any variation in the progression of the sex-specific muscles of the hermaphrodite, over time, whose contractions squeeze on the uterus to help move eggs towards the vulval opening compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "uterine muscle abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001313" ;
    a owl:Class ;
    rdfs:label "uterine muscle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000282 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0005342
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001314
    obo:IAO_0000115 "Any variation in the progression of the sex-specific muscles in the hermaphrodite, over time, that are specialized for egg-laying compared to control. In C. elegans the contractions of the vulval muscles open the lips of the vulva to help in expelling an egg from the uterus (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "vulval muscle abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001314" ;
    a owl:Class ;
    rdfs:label "vulval muscle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000282 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0005821
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001315
    obo:IAO_0000115 "Animals exhibit variations in the electrical properties of any of its cells or tissues compared to control." ;
    oboInOwl:hasExactSynonym "electrophysiology abnormal", "electrophysiology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001315" ;
    a owl:Class ;
    rdfs:label "electrophysiology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000519 .

obo:WBPhenotype_0001316
    obo:IAO_0000115 "Variations in the synaptic currents that are elicited by firing an action potential in a population of axons, compared to control." ;
    oboInOwl:hasNarrowSynonym "evoked postsynaptic current abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001316" ;
    a owl:Class ;
    rdfs:label "evoked postsynaptic current variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002014 .

obo:WBPhenotype_0001317
    obo:IAO_0000115 "The amplitudes of synaptic currents that are elicited by firing an action potential in a population of axons are decreased, compared to those observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001317" ;
    a owl:Class ;
    rdfs:label "evoked postsynaptic amplitude reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001316 .

obo:WBPhenotype_0001318
    obo:IAO_0000115 "Any variation in the currents observed in the absence of presynaptic action potentials and that are elicited by fusion of a single endogenous vesicle of transmitter compared to control." ;
    oboInOwl:hasNarrowSynonym "endogenous synaptic events abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001318" ;
    a owl:Class ;
    rdfs:label "endogenous synaptic events variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002014 .

obo:WBPhenotype_0001319
    obo:IAO_0000115 "The rate (frequency) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is decreased compared to control. Changes in frequency are indicative of presynaptic modifications." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001319" ;
    a owl:Class ;
    rdfs:label "endogenous synaptic event frequency reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001318 .

obo:WBPhenotype_0001320
    obo:IAO_0000115 "The amplitude (magnitude) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is altered compared to control. Changes in amplitude are often interpreted as alterations of postsynaptic responsiveness to the transmitter." ;
    oboInOwl:hasNarrowSynonym "endogenous synaptic amplitude abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001320" ;
    a owl:Class ;
    rdfs:label "endogenous synaptic amplitude variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001318 .

obo:WBPhenotype_0001321
    obo:IAO_0000115 "Animals display variations in the structure, configuration, distribution or ratio of the components of the vesicle-filled varicosities of the synapse compared to control." ;
    oboInOwl:hasNarrowSynonym "presynaptic region morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001321" ;
    a owl:Class ;
    rdfs:label "presynaptic region morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000616 .

obo:WBPhenotype_0001322
    obo:IAO_0000115 "OBSOLETE. Total presynaptic vesicle number is reduced, possibly refecting a defect in the replenishment of synaptic vesicles compared to control." ;
    obo:IAO_0100001 obo:WBPhenotype_0001670 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001322" ;
    a owl:Class ;
    rdfs:comment "Electron microscopic analysis." ;
    rdfs:label "obsolete vesicle number reduced" ;
    owl:deprecated true .

obo:WBPhenotype_0001323
    obo:IAO_0000115 "Animals display variations in the shape or size of their vesicles, which are spherical, membrane-bound fluid-filled organelles, compared to vesicles observed in control animals." ;
    oboInOwl:hasNarrowSynonym "vesicle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001323" ;
    a owl:Class ;
    rdfs:comment "Electron microscopic analysis." ;
    rdfs:label "vesicle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001671 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0031982
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001324
    obo:IAO_0000115 "Cells exhibit variations in their response to ionizing radiation compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "cell ionizing radiation response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001324" ;
    a owl:Class ;
    rdfs:label "cell ionizing radiation response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0071479
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001325
    obo:IAO_0000115 "Animals initiate but do not continue backward movement, similar to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001325" ;
    a owl:Class ;
    rdfs:label "backing not sustained" ;
    rdfs:subClassOf obo:WBPhenotype_0001005 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001570
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0043057
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001326
    obo:IAO_0000115 "Cells exhibit variations in their response to gamma ray radiation compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "cell gamma ray response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001326" ;
    a owl:Class ;
    rdfs:label "cell gamma ray response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001324 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0071480
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001327
    obo:IAO_0000115 "Cells respond to a lower dosage of gamma rays or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001327" ;
    a owl:Class ;
    rdfs:label "cell gamma ray hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001326 .

obo:WBPhenotype_0001328
    obo:IAO_0000115 "The posterior part of the worm is shorter and stouter compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001328" ;
    a owl:Class ;
    rdfs:label "posterior body dumpy" ;
    rdfs:subClassOf obo:WBPhenotype_0000793 .

obo:WBPhenotype_0001329
    obo:IAO_0000115 "Animals exhibit a greater number of bends in their body compared to control. C. elegans posture assumes more than a single sine wave." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001329" ;
    a owl:Class ;
    rdfs:label "curly" ;
    rdfs:subClassOf obo:WBPhenotype_0000001 .

obo:WBPhenotype_0001330
    obo:IAO_0000115 "The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate is reduced compared to that observed in control animals (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "egg laying event rare" ;
    oboInOwl:id "WBPhenotype:0001330" ;
    a owl:Class ;
    rdfs:label "egg laying event infrequent" ;
    rdfs:subClassOf obo:WBPhenotype_0000006, obo:WBPhenotype_0000272 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001331
    obo:IAO_0000115 "Animals display variations in the structure or organization of components of the motor neuron, internal to the cell itself or in relation to the cellular environment compared to that observed in control animals. A motor neuron is a neuronal cell that synapses to an effector (muscle, gland etc.)." ;
    oboInOwl:hasNarrowSynonym "motor neuron morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001331" ;
    a owl:Class ;
    rdfs:comment "WBbt:0005409." ;
    rdfs:label "motor neuron morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000905 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005409
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001332
    obo:IAO_0000115 "Animals display variations in the number of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "vesicle number abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001332" ;
    a owl:Class ;
    rdfs:label "vesicle number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001671 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0031982
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001333
    obo:IAO_0000115 "The body of a neuron is not where it should be when compared to control animals; it is absent or misplaced." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001333" ;
    a owl:Class ;
    rdfs:label "neuron cell body absent misplaced" ;
    rdfs:subClassOf obo:WBPhenotype_0000816 .

obo:WBPhenotype_0001334
    obo:IAO_0000115 "Any variation in the form, structure or composition of the muscles of the adult hermaphrodite reproductive system compared to control. In C. elegans hermaphrodites these muscles include the vulval and uterine muscles, located near the vulva in the midbody, which all derive from the M myoblast (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite sex muscle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001334" ;
    a owl:Class ;
    rdfs:label "hermaphrodite sex muscle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001335 .

obo:WBPhenotype_0001335
    obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the hermaphrodite reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite reproductive system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001335" ;
    a owl:Class ;
    rdfs:label "hermaphrodite reproductive system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000605 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005747
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0007849
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001336
    obo:IAO_0000115 "Males sire no cross progeny." ;
    oboInOwl:hasExactSynonym "no male progeny" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001336" ;
    a owl:Class ;
    rdfs:label "male mating efficiency eliminated" ;
    rdfs:subClassOf obo:WBPhenotype_0000843 .

obo:WBPhenotype_0001337
    obo:IAO_0000115 "Animals exhibit variations in their response to a specific adrenergic receptor antagonist compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "adrenergic receptor antagonist response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001337" ;
    a owl:Class ;
    rdfs:label "adrenergic receptor antagonist response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0001338
    obo:IAO_0000115 "Animals fail to respond to the concentration of phentolamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001338" ;
    a owl:Class ;
    rdfs:label "phentolamine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001337 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_8081
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001339
    obo:IAO_0000115 "Animals are not induced to lay eggs in reponse to exogenous levamisole. In C. elegans, levamisole stimulates egg-laying." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001339" ;
    a owl:Class ;
    rdfs:label "egg laying levamisole resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000421, obo:WBPhenotype_0001101 .

obo:WBPhenotype_0001340
    obo:IAO_0000115 "Animals are not induced to lay eggs in reponse to exogenous imipramine. In C. elegans, imipramine stimulates egg-laying." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001340" ;
    a owl:Class ;
    rdfs:label "egg laying imipramine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000340, obo:WBPhenotype_0001101 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001552
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_47499
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001341
    obo:IAO_0000115 "Animals are not induced to lay eggs in reponse to exogenous phentolamine. In C. elegans, phentolamine stimulates egg-laying." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001341" ;
    a owl:Class ;
    rdfs:label "egg laying phentolamine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001101, obo:WBPhenotype_0001338 .

obo:WBPhenotype_0001342
    obo:IAO_0000115 "Animals respond to exogenous imipramine at a lower concentration or within a shorter time period than control animals under the same conditions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001342" ;
    a owl:Class ;
    rdfs:label "egg laying imipramine hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001101 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001551
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_47499
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001343
    obo:IAO_0000115 "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a meiotic cell cycle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001343" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "meiotic spindle defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000759, obo:WBPhenotype_0001868 .

obo:WBPhenotype_0001344
    obo:IAO_0000115 "Intracellular membrane bound compartments vary in shape or size from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organelle organization biogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001344" ;
    a owl:Class ;
    rdfs:label "organelle organization biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0010002 .

obo:WBPhenotype_0001345
    obo:IAO_0000115 "Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." ;
    oboInOwl:hasNarrowSynonym "cytoskeleton organization biogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001345" ;
    a owl:Class ;
    rdfs:label "cytoskeleton organization biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007010
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001346
    obo:IAO_0000115 "Any variation in the dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins compared to control." ;
    oboInOwl:hasExactSynonym "actin cytoskeleton dynamics variant" ;
    oboInOwl:hasNarrowSynonym "actin cytoskeleton dynamic abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001346" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "actin cytoskeleton dynamics phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0001587 .

obo:WBPhenotype_0001347
    obo:IAO_0000115 "Any variation in the series of molecular signals in which an intestinal cell uses calcium ions to convert an extracellular signal into a response, compared to control." ;
    oboInOwl:hasNarrowSynonym "intestinal calcium signaling abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001347" ;
    a owl:Class ;
    rdfs:label "intestinal calcium signaling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001093, obo:WBPhenotype_0002170 .

obo:WBPhenotype_0001348
    obo:IAO_0000115 "Variations in the form or composition of a structure in the cell nucleus which contains the genetic material encoded as DNA and surrounded by histone proteins and other regulatory elements compared to control. In C. elegans the normal cell contains 5 pairs of 'autosomes' and one or two X chromosomes (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "chromosome morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001348" ;
    a owl:Class ;
    rdfs:label "chromosome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001028 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005694
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001349
    obo:IAO_0000115 "Variations in the processes that incorporate phosphate groups to one or more amino acids within a protein, compared to control." ;
    oboInOwl:hasNarrowSynonym "protein phosphorylation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001349" ;
    a owl:Class ;
    rdfs:label "protein phosphorylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006468
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001350
    obo:IAO_0000115 "Animals exhibit higher levels of protein phosphorylation compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001350" ;
    a owl:Class ;
    rdfs:label "protein phosphorylation increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001349 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006468
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001351
    obo:IAO_0000115 "Animals exhibit decreased levels of protein phosphorylation compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001351" ;
    a owl:Class ;
    rdfs:label "protein phosphorylation reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001349 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006468
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001352
    obo:IAO_0000115 "Variations in the chemical reactions and pathways of the endoplasmic reticulum compared to control." ;
    oboInOwl:hasNarrowSynonym "endoplasmic reticulum metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "er metabolism abnormal" ;
    oboInOwl:id "WBPhenotype:0001352" ;
    a owl:Class ;
    rdfs:label "endoplasmic reticulum metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001283 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008152
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:GO_0005783
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001353
    obo:IAO_0000115 "The coordinated movement during prophase of the two centrosomes and the two pronuclei towards the center of the one cell embryo is abolished." ;
    oboInOwl:hasNarrowSynonym "centration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001353" ;
    a owl:Class ;
    rdfs:label "centration defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001152 .

obo:WBPhenotype_0001354
    obo:IAO_0000115 "Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas)." ;
    oboInOwl:hasExactSynonym "actin cytoskeleton filament morphology abnormal", "actin cytoskeleton filament morphology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001354" ;
    a owl:Class ;
    rdfs:label "actin cytoskeleton filament morphology phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0001587 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005884
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001355
    obo:IAO_0000115 "Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "gonad morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001355" ;
    a owl:Class ;
    rdfs:label "gonad morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000605 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005175
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001356
    obo:IAO_0000115 "Any variation in the form, structure or composition of the muscles of the adult male reproductive system compared to control. In C. elegans males, the M myoblast gives rise to a much larger set of specialized muscles, compared to hermaphrodites, which differentiate within the tail region (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "male sex muscle morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001356" ;
    a owl:Class ;
    rdfs:label "male sex muscle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001024 .

obo:WBPhenotype_0001357
    obo:IAO_0000115 "Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male gametes compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "male gonad morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001357" ;
    a owl:Class ;
    rdfs:label "male gonad morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001024 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006794
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001358
    obo:IAO_0000115 "Male animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals." ;
    oboInOwl:hasNarrowSynonym "male nervous system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001358" ;
    a owl:Class ;
    rdfs:label "male nervous system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001024 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005735
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0007850
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001359
    obo:IAO_0000115 "Animals exhibit variations in the structure and organization of the chamber in the male tail that extends from the termination of four canals (vas deferens, gut, and left and right spicule channels) to just before the cloaca, from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "proctodeum morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001359" ;
    a owl:Class ;
    rdfs:label "proctodeum morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000070 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006795
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001360
    obo:IAO_0000115 "Hermaphrodites fail to produce any viable progeny via self-fertilization. However, such hermaphrodites can successfully reproduce if mated to control males." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001360" ;
    a owl:Class ;
    rdfs:label "hermaphrodite self sterile" ;
    rdfs:subClassOf obo:WBPhenotype_0000694 .

obo:WBPhenotype_0001361
    obo:IAO_0000115 "Any variation in the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells compared to control." ;
    oboInOwl:hasNarrowSynonym "chromosome condensation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001361" ;
    a owl:Class ;
    rdfs:label "chromosome condensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030261
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001362
    obo:IAO_0000115 "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis in eukaryotic cells is abolished." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001362" ;
    a owl:Class ;
    rdfs:label "chromosome condensation failure" ;
    rdfs:subClassOf obo:WBPhenotype_0001361 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030261
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001363
    obo:IAO_0000115 "The head contains cavities, possibly indicative of inappropriate cell death." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "head vacuole" ;
    oboInOwl:id "WBPhenotype:0001363" ;
    a owl:Class ;
    rdfs:label "head cavity" ;
    rdfs:subClassOf obo:WBPhenotype_0000071 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002112
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005739
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001364
    obo:IAO_0000115 "Any variation in the form, structure or composition of the flattened structure extending laterally at the extreme tip of the adult male consisting of nine pairs of sensory rays that lie within a web-like cuticle compared to control." ;
    oboInOwl:hasNarrowSynonym "male fan morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001364" ;
    a owl:Class ;
    rdfs:label "male fan morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000070 .

obo:WBPhenotype_0001365
    obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the male bursa over time, from its formation to the mature structure, compared to control. The male bursa consists of the lateral fan and rays (WormAtlas)." ;
    oboInOwl:hasNarrowSynonym "male bursa development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001365" ;
    a owl:Class ;
    rdfs:label "male bursa development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001297 .

obo:WBPhenotype_0001366
    obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the male fan over time, from its formation to the mature structure, compared to control." ;
    oboInOwl:hasNarrowSynonym "male fan development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001366" ;
    a owl:Class ;
    rdfs:label "male fan development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001365 .

obo:WBPhenotype_0001367
    obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the male proctodeum over time, from its formation to the mature structure, compared to control. The union of the vas deferens and the intestine give rise to the proctodeum which contains copulatory spicules." ;
    oboInOwl:hasNarrowSynonym "proctodeum development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001367" ;
    a owl:Class ;
    rdfs:label "proctodeum development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001297 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006795
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001368
    obo:IAO_0000115 "Animals lack the somatic gonad structure that connects the distal gonad arm to the uterus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001368" ;
    a owl:Class ;
    rdfs:label "spermatheca absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001662 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005319
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001369
    obo:IAO_0000115 "Variations in the selective and non-covalent physical association between two or more proteins, or a protein and nucleic acid/macromolecular complex, compared to control." ;
    oboInOwl:hasNarrowSynonym "protein interaction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001369" ;
    a owl:Class ;
    rdfs:label "protein interaction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0065003
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001370
    obo:IAO_0000115 "Variations in the selective and non-covalent physical association between two or more proteins, compared to control." ;
    oboInOwl:hasNarrowSynonym "protein protein interaction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001370" ;
    a owl:Class ;
    rdfs:label "protein protein interaction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001369 .

obo:WBPhenotype_0001371
    obo:IAO_0000115 "Variations in the selective and non-covalent physical association between a protein and a specific RNA sequence, compared to control." ;
    oboInOwl:hasNarrowSynonym "protein RNA interaction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001371" ;
    a owl:Class ;
    rdfs:label "protein RNA interaction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001369 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0022618
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001372
    obo:IAO_0000115 "Variations in the selective and non-covalent physical association between a protein and a specific DNA sequence, compared to control." ;
    oboInOwl:hasNarrowSynonym "protein DNA interaction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001372" ;
    a owl:Class ;
    rdfs:label "protein DNA interaction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001369 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0065004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001373
    obo:IAO_0000115 "Animals lack a specific protein-RNA interaction observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001373" ;
    a owl:Class ;
    rdfs:label "protein RNA interaction abolished" ;
    rdfs:subClassOf obo:WBPhenotype_0001371 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0022618
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001374
    obo:IAO_0000115 "The shape and size of nuclei as well as the distribution of nucleoporins are strongly affected." ;
    oboInOwl:hasNarrowSynonym "pronuclear nuclear appearance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Pna" ;
    oboInOwl:id "WBPhenotype:0001374" ;
    a owl:Class ;
    rdfs:label "pronuclear nuclear appearance variant emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000764 .

obo:WBPhenotype_0001375
    obo:IAO_0000115 "The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001375" ;
    a owl:Class ;
    rdfs:label "transgene expression undetectable" ;
    rdfs:subClassOf obo:WBPhenotype_0001278 .

obo:WBPhenotype_0001376
    obo:IAO_0000115 "The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection in specific cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001376" ;
    a owl:Class ;
    rdfs:label "transgene expression undetectable cell specific" ;
    rdfs:subClassOf obo:WBPhenotype_0001375 .

obo:WBPhenotype_0001377
    obo:IAO_0000115 "Variations in the generation of foci that mark crossover recombination events, compared to control. These foci mark the boundary of asymmetric synaptonemal complex disassembly." ;
    oboInOwl:hasNarrowSynonym "break induced focus formation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001377" ;
    a owl:Class ;
    rdfs:label "break induced focus formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001256, obo:WBPhenotype_0001324 .

obo:WBPhenotype_0001378
    obo:IAO_0000115 "Any variation in the cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle compared to control animals." ;
    oboInOwl:hasNarrowSynonym "mitotic chromosome segregation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001378" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "mitotic chromosome segregation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000773 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000070
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001379
    obo:IAO_0000115 "Animals exhibit variations in their response to a specific toxic chemical compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism toxic chemical response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001379" ;
    a owl:Class ;
    rdfs:label "organism toxic chemical response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000523 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009636
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001380
    obo:IAO_0000115 "Animals respond to anoxic (trace oxygen levels) stress after a shorter exposure time compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001380" ;
    a owl:Class ;
    rdfs:label "anoxia hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0002424 .

obo:WBPhenotype_0001381
    obo:IAO_0000115 "Animals fail to respond to trace amounts of oxygen that elicit a response in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001381" ;
    a owl:Class ;
    rdfs:label "anoxia resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0002424 .

obo:WBPhenotype_0001382
    obo:IAO_0000115 "Variations in the covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications), compared to control. This includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ;
    oboInOwl:hasNarrowSynonym "protein modification abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001382" ;
    a owl:Class ;
    rdfs:label "protein modification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000112 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0036211
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001383
    obo:IAO_0000115 "Variations in the processes that incorporate methyl groups to one or more amino acids within a protein, compared to control." ;
    oboInOwl:hasNarrowSynonym "protein methylation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001383" ;
    a owl:Class ;
    rdfs:label "protein methylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006479
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001384
    obo:IAO_0000115 "Animals exhibit a reduction in the production of new individuals that contain some portion of their genetic material inherited from that organism as a result of defective gametes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001384" ;
    a owl:Class ;
    rdfs:label "fertility reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000145 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001834
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001385
    obo:IAO_0000115 "Relatively unspecialized germ cells prematurely acquire the specialized properties of mature oocytes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001385" ;
    a owl:Class ;
    rdfs:label "precocious oogenesis" ;
    rdfs:subClassOf obo:WBPhenotype_0000186, obo:WBPhenotype_0000439 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000694
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048477
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001386
    obo:IAO_0000115 "Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) in adult hermaphrodites during sexual reproduction." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001386" ;
    a owl:Class ;
    rdfs:label "fertilization defective hermaphrodite" ;
    rdfs:subClassOf obo:WBPhenotype_0000983 .

obo:WBPhenotype_0001387
    obo:IAO_0000115 "Failure of male-derived sperm to fuse with an oocyte during sexual reproduction." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001387" ;
    a owl:Class ;
    rdfs:label "fertilization defect male" ;
    rdfs:subClassOf obo:WBPhenotype_0000983 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009566
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000056
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001388
    obo:IAO_0000115 "Organisms respond to a lower dosage of gamma rays or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001388" ;
    a owl:Class ;
    rdfs:label "organism hypersensitive gamma irradiation" ;
    rdfs:subClassOf obo:WBPhenotype_0000497, obo:WBPhenotype_0000711 .

obo:WBPhenotype_0001389
    obo:IAO_0000115 "Cells fail to respond to the dosage of gamma irradiation that elicits a response in control animals. Alternatively, cells require longer exposure times to gamma irradiation to mimic the response observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001389" ;
    a owl:Class ;
    rdfs:label "cell gamma ray resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001326 .

obo:WBPhenotype_0001390
    obo:IAO_0000115 "Cells respond to a lower dosage of UV or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001390" ;
    a owl:Class ;
    rdfs:label "cell UV hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000100 .

obo:WBPhenotype_0001391
    obo:IAO_0000115 "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001391" ;
    a owl:Class ;
    rdfs:label "gamma ray induced apoptosis increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000183, obo:WBPhenotype_0001326 .

obo:WBPhenotype_0001392
    obo:IAO_0000115 "Cells of the animals cease during one of its replicative phases (G1, S, G2, M)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001392" ;
    a owl:Class ;
    rdfs:label "cell cycle arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0001995 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000297
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007049
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001393
    obo:IAO_0000115 "Variations in the processes that reduce the internal pH of a cell (measured by the concentration of the hydrogen ion), compared to control." ;
    oboInOwl:hasNarrowSynonym "cell acidification abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001393" ;
    a owl:Class ;
    rdfs:label "cell acidification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000585 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051452
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001394
    obo:IAO_0000115 "Animals lack the capacity to reduce the internal pH of a cell." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "no pumping" ;
    oboInOwl:id "WBPhenotype:0001394" ;
    a owl:Class ;
    rdfs:label "cell acidification defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001393 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001624
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051452
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001395
    obo:IAO_0000115 "Vacuoles accumulate in the body. A vacuole is a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001395" ;
    a owl:Class ;
    rdfs:label "body vacuole" ;
    rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0002615 .

obo:WBPhenotype_0001396
    obo:IAO_0000115 "Animals completely lack any pharyngeal pumping motion." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001396" ;
    a owl:Class ;
    rdfs:label "pumping absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043050
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001397
    obo:IAO_0000115 "Animals exhibit an increase in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001397" ;
    a owl:Class ;
    rdfs:label "necrotic cell death increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000415 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0070265
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001398
    obo:IAO_0000115 "Animals display variations in the structure, organization of components, or spatial pattern of any projection stemming from a neuronal cell, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "neurite morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001398" ;
    a owl:Class ;
    rdfs:label "neurite morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000905 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043005
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001399
    obo:IAO_0000115 "Any variation in the structure, form or composition of the semipermeable lipid bilayer that creates a boundary between the interior and exterior environment for cells, cellular organelles and tissues, within an organism compared to control." ;
    oboInOwl:hasNarrowSynonym "cell membrane morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001399" ;
    a owl:Class ;
    rdfs:label "cell membrane morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005886
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001400
    obo:IAO_0000115 "Animals exhibit variations in the measured expression of a protein compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "level of protein expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001400" ;
    a owl:Class ;
    rdfs:label "level of protein expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000112 .

obo:WBPhenotype_0001401
    obo:IAO_0000115 "The morphological appearance of mitochondria is varied compared to control animals." ;
    oboInOwl:hasExactSynonym "mitochondria morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001401" ;
    a owl:Class ;
    rdfs:label "mitochondria morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005739
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001402
    obo:IAO_0000115 "Mitochondria are interconnected by thin tubules of mitochondrial inner or outer membrane." ;
    oboInOwl:hasNarrowSynonym "connected mitochodria muscle", "connected mitochondria epithelial" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001402" ;
    a owl:Class ;
    rdfs:label "connected mitochondria" ;
    rdfs:subClassOf obo:WBPhenotype_0001401 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000642
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0005739
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005739
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001403
    obo:IAO_0000115 "Any variation in the placement of a protein, as detected by antibody staining, within in a cell or cellular compartment compared to control." ;
    oboInOwl:hasNarrowSynonym "antibody subcellular localization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001403" ;
    a owl:Class ;
    rdfs:label "antibody subcellular localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000424 .

obo:WBPhenotype_0001404
    obo:IAO_0000115 "Any variation that results in the detection of protein expression in cells/tissues through antibody staining, that is otherwise not observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001404" ;
    a owl:Class ;
    rdfs:label "ectopic expression antibody" ;
    rdfs:subClassOf obo:WBPhenotype_0000424 .

obo:WBPhenotype_0001405
    obo:IAO_0000115 "Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding." ;
    oboInOwl:hasNarrowSynonym "protein aggregation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001405" ;
    a owl:Class ;
    rdfs:label "protein aggregation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001370 .

obo:WBPhenotype_0001406
    obo:IAO_0000115 "Variations that result in a decrease in protein expression in male animals compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001406" ;
    a owl:Class ;
    rdfs:label "protein expression reduced male" ;
    rdfs:subClassOf obo:WBPhenotype_0000120 .

obo:WBPhenotype_0001407
    obo:IAO_0000115 "Variations that result in a decrease in protein expression in specific cells compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001407" ;
    a owl:Class ;
    rdfs:label "protein expression reduced cell specific" ;
    rdfs:subClassOf obo:WBPhenotype_0000120 .

obo:WBPhenotype_0001408
    obo:IAO_0000115 "Any variation in the cellular or subcellular distribution of a protein compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "pattern protein expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001408" ;
    a owl:Class ;
    rdfs:label "pattern protein expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000112 .

obo:WBPhenotype_0001409
    obo:IAO_0000115 "Any variation that results in the cellular expression of a protein in cells/tissues, that is otherwise not observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001409" ;
    a owl:Class ;
    rdfs:label "protein expression ectopic" ;
    rdfs:subClassOf obo:WBPhenotype_0001408 .

obo:WBPhenotype_0001410
    obo:IAO_0000115 "Animals fail to express a given protein or class of proteins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001410" ;
    a owl:Class ;
    rdfs:label "protein expression absent" ;
    rdfs:subClassOf obo:WBPhenotype_0000120 .

obo:WBPhenotype_0001411
    obo:IAO_0000115 "Animals exhibit an altered display of glycosylated proteins or lipids or altered access to glycosylated moieties along their surface from that observed in control animals of the same developmental stage. In C. elegans, variations in surface accessible glycosylated species are often revealed by altered lectin-binding from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "Srf", "cuticle carbohydrate surface abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ectopic lectin binding" ;
    oboInOwl:id "WBPhenotype:0001411" ;
    a owl:Class ;
    rdfs:label "cuticle carbohydrate surface variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001210 .

obo:WBPhenotype_0001412
    obo:IAO_0000115 "Animals exhibit variations in the organization of the longitudinal ridges on the cuticle along the length of the animal, from that observed for control animals of the same developmental stage." ;
    oboInOwl:hasNarrowSynonym "alae morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001412" ;
    a owl:Class ;
    rdfs:label "alae morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000948 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007832
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001413
    obo:IAO_0000115 "Animals do not exhibit tail-swelling in response to infection by a bacterial pathogen (such as Microbacterium nematophilum) compared to control." ;
    oboInOwl:hasBroadSynonym "Bus" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001413" ;
    a owl:Class ;
    rdfs:label "bacterially unswollen" ;
    rdfs:subClassOf obo:WBPhenotype_0000073, obo:WBPhenotype_0001014, obo:WBPhenotype_0002545 .

obo:WBPhenotype_0001414
    obo:IAO_0000115 "Males exhibit defects in the specific actions or reactions that are associated with reproduction." ;
    oboInOwl:hasBroadSynonym "Cod" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001414" ;
    a owl:Class ;
    rdfs:label "male mating defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000648 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060179
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000056
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001415
    obo:IAO_0000115 "Animals exhibit variations that result in variations in the ability of or extent to which pathogens adhere to the surface of animals, compared to control." ;
    oboInOwl:hasNarrowSynonym "pathogen adherence abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001415" ;
    a owl:Class ;
    rdfs:label "pathogen adherence variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001012 .

obo:WBPhenotype_0001416
    obo:IAO_0000115 "Pathogens are unable to adhere/colonize the surface of host animals. This defect is often associated with changes in cuticle surface properties of the host." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001416" ;
    a owl:Class ;
    rdfs:label "pathogen adherence defect" ;
    rdfs:subClassOf obo:WBPhenotype_0001014, obo:WBPhenotype_0002461 .

obo:WBPhenotype_0001417
    obo:IAO_0000115 "Any variation in the state or activity of an organism in response to extreme dryness or drought-like conditions, compared to control ." ;
    oboInOwl:hasNarrowSynonym "organism desication response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001417" ;
    a owl:Class ;
    rdfs:label "organism desiccation response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009269
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001418
    obo:IAO_0000115 "Animals respond to less severe drought-like conditions or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001418" ;
    a owl:Class ;
    rdfs:label "organism hypersensitive desiccation" ;
    rdfs:subClassOf obo:WBPhenotype_0001417 .

obo:WBPhenotype_0001419
    obo:IAO_0000115 "Animals respond to emetine at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001419" ;
    a owl:Class ;
    rdfs:label "emetine hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_4781
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001420
    obo:IAO_0000115 "Animals can move thorough a lawn of bacterially produced biofilm without accumulating an enormous amount of biofilm on its nose. When C. elegans is exposed to certain bacteria (e.g., Y. pestis), a biofilm accumulates on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth." ;
    oboInOwl:hasBroadSynonym "Bah" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001420" ;
    a owl:Class ;
    rdfs:label "biofilm absent head" ;
    rdfs:subClassOf obo:WBPhenotype_0001415 .

obo:WBPhenotype_0001421
    obo:IAO_0000115 "Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control." ;
    oboInOwl:hasNarrowSynonym "endocytic transport abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001421" ;
    a owl:Class ;
    rdfs:label "endocytic transport variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006897
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001422
    obo:IAO_0000115 "Animals exhibit defects in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001422" ;
    a owl:Class ;
    rdfs:label "endocytic transport defect" ;
    rdfs:subClassOf obo:WBPhenotype_0001421 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006897
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001423
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the coelomocyte to carry out its normal functions or activities, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "coelomocyte physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001423" ;
    a owl:Class ;
    rdfs:label "coelomocyte physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005751
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001424
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the oocyte to carry out its normal functions or activities, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "oocyte physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001424" ;
    a owl:Class ;
    rdfs:label "oocyte physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006797
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001425
    obo:IAO_0000115 "Animals exhibit defects in the cell-mediated uptake of external materials via receptor activity. Receptor-mediated endocytosis ensures specificity of transport and generally occurs via clathrin-coated pits and vesicles. In C. elegans, this is often judged by the lack of yolk uptake in oocytes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Rme" ;
    oboInOwl:id "WBPhenotype:0001425" ;
    a owl:Class ;
    rdfs:comment "Possible XP = GO:0006898." ;
    rdfs:label "receptor mediated endocytosis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001422, obo:WBPhenotype_0001424 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006898
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001426
    obo:IAO_0000115 "Fluid-phase endocytosis by coelomocytes is less frequent or efficient compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Cup" ;
    oboInOwl:id "WBPhenotype:0001426" ;
    a owl:Class ;
    rdfs:label "coelomocyte endocytosis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001422, obo:WBPhenotype_0001423 .

obo:WBPhenotype_0001427
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control animals." ;
    oboInOwl:hasNarrowSynonym "cytoplasmic appearance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001427" ;
    a owl:Class ;
    rdfs:label "cytoplasmic appearance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0010002 .

obo:WBPhenotype_0001428
    obo:IAO_0000115 "Vacuoles accumulate in the intestine." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001428" ;
    a owl:Class ;
    rdfs:label "intestinal vacuole" ;
    rdfs:subClassOf obo:WBPhenotype_0000710, obo:WBPhenotype_0002615 .

obo:WBPhenotype_0001429
    obo:IAO_0000115 "Animals accumulate an excess of vesicle-like structures in cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001429" ;
    a owl:Class ;
    rdfs:label "granules cytoplasm" ;
    rdfs:subClassOf obo:WBPhenotype_0001427 .

obo:WBPhenotype_0001430
    obo:IAO_0000115 "Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome, compared to control." ;
    oboInOwl:hasNarrowSynonym "lysosome organization biogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001430" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "lysosome organization biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007040
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001431
    obo:IAO_0000115 "Male tails fail to undergo tip retraction thereby forming a 'leptoderan' or 'pointed' adult tail." ;
    oboInOwl:hasBroadSynonym "Lep" ;
    oboInOwl:hasExactSynonym "male tail spike" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "leptoderan tail" ;
    oboInOwl:id "WBPhenotype:0001431" ;
    a owl:Class ;
    rdfs:label "pointed tail tip male" ;
    rdfs:subClassOf obo:WBPhenotype_0000070 .

obo:WBPhenotype_0001432
    obo:IAO_0000115 "Adult males exhibit a truncated tail, often without a fan or have well-developed fans but squarish, truncated back ends compared to control. In C. elegans this is due to precocious male tail tip retraction beginning in the early L3 stage (normally retraction begins in the L4 stage). Condition can be lethal if the function of the anus is affected." ;
    oboInOwl:hasBroadSynonym "Ore" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001432" ;
    a owl:Class ;
    rdfs:label "over retracted male tail" ;
    rdfs:subClassOf obo:WBPhenotype_0000070, obo:WBPhenotype_0001297 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001477
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005741
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001433
    obo:IAO_0000115 "Two or more individual cells form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes at an earlier stage of development compared to comparable cells in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001433" ;
    a owl:Class ;
    rdfs:label "precocious cell fusion" ;
    rdfs:subClassOf obo:WBPhenotype_0000165, obo:WBPhenotype_0000439 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000694
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000768
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001434
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific chemical concentration gradient compared to control. Directed movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ;
    oboInOwl:hasNarrowSynonym "chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Che" ;
    oboInOwl:id "WBPhenotype:0001434" ;
    a owl:Class ;
    rdfs:label "chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001040 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006935
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001435
    obo:IAO_0000115 "Failure in directed movement in response to ammonium chloride compared to control. In C. elegans, NH4Cl is an attractant. NH4Cl has also subsequently been used to assay for Cl- attraction in C. elegans." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "chloride chemotaxis defective" ;
    oboInOwl:id "WBPhenotype:0001435" ;
    a owl:Class ;
    rdfs:label "ammonium chloride chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001460 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_31206
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001436
    obo:IAO_0000115 "Animals tend to initiate a response more often, compared to control, after nose-on collisions with an object. In C. elegans, animals initiate backwards movement in response to nose touch." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001436" ;
    a owl:Class ;
    rdfs:label "nose touch hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0004026 .

obo:WBPhenotype_0001437
    obo:IAO_0000115 "Animals execute a response, via directed movement to octanol at a lower concentration or shorter exposure time compared to control. In C. elegans, animals avoid octanol." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001437" ;
    a owl:Class ;
    rdfs:label "octanol chemotaxis hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001452 .

obo:WBPhenotype_0001438
    obo:IAO_0000115 "Animals fail to move towards attractive volatile organic molecules. In C. elegans, these compounds are sensed by the AWA and AWC neurons." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001438" ;
    a owl:Class ;
    rdfs:label "odorant positive chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000015, obo:WBPhenotype_0000265 .

obo:WBPhenotype_0001439
    obo:IAO_0000115 "Animals fail to move towards attractive anions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001439" ;
    a owl:Class ;
    rdfs:label "anion positive chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001052, obo:WBPhenotype_0001441 .

obo:WBPhenotype_0001440
    obo:IAO_0000115 "Animals fail to move towards attractive cations." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001440" ;
    a owl:Class ;
    rdfs:label "cation positive chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001051, obo:WBPhenotype_0001441 .

obo:WBPhenotype_0001441
    obo:IAO_0000115 "Animals fail to move towards attractive water-soluble chemicals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "water soluble positive chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001441" ;
    a owl:Class ;
    rdfs:label "aqueous positive chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000015, obo:WBPhenotype_0001047 .

obo:WBPhenotype_0001442
    obo:IAO_0000115 "Failure in directed movement in response to sodium acetate. In C. elegans, sodium acetate is an attractant. Sodium acetate has also subsequently been used to assay for Na+ attraction in C. elegans." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "sodium chemotaxis defective" ;
    oboInOwl:id "WBPhenotype:0001442" ;
    a owl:Class ;
    rdfs:label "sodium acetate chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001461 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_32954
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001443
    obo:IAO_0000115 "Animals exhibit variations in response to water-soluble chemicals, compared to control." ;
    oboInOwl:hasNarrowSynonym "aqueous chemosensory response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "water soluble chemosensory response abnormal" ;
    oboInOwl:id "WBPhenotype:0001443" ;
    a owl:Class ;
    rdfs:label "aqueous chemosensory response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001040 .

obo:WBPhenotype_0001444
    obo:IAO_0000115 "Animals do not exhibit characteristic desensitization to a water-soluble chemo-attractive signal in a time-concentration dependent and reversible manner compared to control." ;
    oboInOwl:hasNarrowSynonym "aqueous adaptation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "gustatory plasticity abnormal", "water soluble adaptation abnormal" ;
    oboInOwl:id "WBPhenotype:0001444" ;
    a owl:Class ;
    rdfs:label "aqueous adaptation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001443 .

obo:WBPhenotype_0001445
    obo:IAO_0000115 "Animals do not exhibit characteristic chemoattractive desensitization to sodium acetate in a time-concentration dependent and reversible manner compared to control." ;
    oboInOwl:hasNarrowSynonym "sodium acetate adaptation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001445" ;
    a owl:Class ;
    rdfs:label "sodium acetate adaptation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001444 .

obo:WBPhenotype_0001446
    obo:IAO_0000115 "Animals do not exhibit characteristic chemoattractive desensitization to sodium chloride in a time-concentration dependent and reversible manner compared to control." ;
    oboInOwl:hasNarrowSynonym "sodium chloride adaptation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001446" ;
    a owl:Class ;
    rdfs:label "sodium chloride adaptation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001444 .

obo:WBPhenotype_0001447
    obo:IAO_0000115 "Animals do not exhibit characteristic chemoattractive desensitization to ammonium chloride in a time-concentration dependent and reversible manner compared to control." ;
    oboInOwl:hasNarrowSynonym "ammonium chloride adaptation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001447" ;
    a owl:Class ;
    rdfs:label "ammonium chloride adaptation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001444 .

obo:WBPhenotype_0001448
    obo:IAO_0000115 "Animals fail to move away from repellant volatile organic chemicals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "volatile negative chemotaxis defective" ;
    oboInOwl:id "WBPhenotype:0001448" ;
    a owl:Class ;
    rdfs:label "odorant negative chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001455 .

obo:WBPhenotype_0001449
    obo:IAO_0000115 "Animals fail to move away from repellent water soluble chemicals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "water soluble chemotaxis defective" ;
    oboInOwl:id "WBPhenotype:0001449" ;
    a owl:Class ;
    rdfs:label "aqueous negative chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001450 .

obo:WBPhenotype_0001450
    obo:IAO_0000115 "Animals exhibit variations through directed movement, in response to repellant water soluble chemicals, compared to control." ;
    oboInOwl:hasNarrowSynonym "aqueous negative chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "water soluble chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001450" ;
    a owl:Class ;
    rdfs:label "aqueous negative chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000481, obo:WBPhenotype_0001443 .

obo:WBPhenotype_0001451
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of garlic compared to control. In C. elegans, garlic is typically a repellant." ;
    oboInOwl:hasNarrowSynonym "garlic chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001451" ;
    a owl:Class ;
    rdfs:label "garlic chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001450 .

obo:WBPhenotype_0001452
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of octanol. In C. elegans, octanol is typically a repellant." ;
    oboInOwl:hasNarrowSynonym "octanol chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001452" ;
    a owl:Class ;
    rdfs:label "octanol chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001455 .

obo:WBPhenotype_0001453
    obo:IAO_0000115 "Animals exhibit variations in their avoidance response to high concentrations of sodium chloride solution compared to control." ;
    oboInOwl:hasNarrowSynonym "high sodium chloride concentration osmotic avoidance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001453" ;
    a owl:Class ;
    rdfs:label "high sodium chloride concentration osmotic avoidance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000663 .

obo:WBPhenotype_0001454
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of the bitter tastant quinine, a water soluble molecule. In C. elegans, quinine is typically a repellant." ;
    oboInOwl:hasNarrowSynonym "quinine chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001454" ;
    a owl:Class ;
    rdfs:label "quinine chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001939 .

obo:WBPhenotype_0001455
    obo:IAO_0000115 "Animals exhibit variations through directed movement, in response to repellant volatile organic chemicals, compared to control." ;
    oboInOwl:hasNarrowSynonym "odorant negative chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "volatile negative chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001455" ;
    a owl:Class ;
    rdfs:label "odorant negative chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000481, obo:WBPhenotype_0001048 .

obo:WBPhenotype_0001456
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of nonanone. In C. elegans, nonanone is typically a repellant." ;
    oboInOwl:hasNarrowSynonym "nonanone chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001456" ;
    a owl:Class ;
    rdfs:label "nonanone chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001455 .

obo:WBPhenotype_0001457
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of bromide. In C. elegans, bromide is typically an attractant." ;
    oboInOwl:hasNarrowSynonym "bromide chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001457" ;
    a owl:Class ;
    rdfs:label "bromide chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001052 .

obo:WBPhenotype_0001458
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of chloride." ;
    oboInOwl:hasNarrowSynonym "chloride chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ammonium chloride chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001458" ;
    a owl:Class ;
    rdfs:label "chloride chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001052 .

obo:WBPhenotype_0001459
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of iodide." ;
    oboInOwl:hasNarrowSynonym "iodide chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001459" ;
    a owl:Class ;
    rdfs:label "iodide chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001052 .

obo:WBPhenotype_0001460
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of ammonium chloride. In C. elegans, at specific concentrations, ammonium chloride is an attractant. NH4Cl has also been used to assay for Cl- attraction." ;
    oboInOwl:hasNarrowSynonym "ammonium chloride chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "chloride chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001460" ;
    a owl:Class ;
    rdfs:label "ammonium chloride chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001047 .

obo:WBPhenotype_0001461
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium acetate. In C. elegans, at specific concentrations, sodium acetate is an attractant. Sodium acetate has also been used to assay for Na+ attraction." ;
    oboInOwl:hasNarrowSynonym "sodium acetate chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "sodium chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001461" ;
    a owl:Class ;
    rdfs:label "sodium acetate chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001047 .

obo:WBPhenotype_0001462
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium chloride. In C. elegans, at specific concentrations, sodium chloride is an attractant." ;
    oboInOwl:hasNarrowSynonym "sodium chloride chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001462" ;
    a owl:Class ;
    rdfs:label "sodium chloride chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001047 .

obo:WBPhenotype_0001463
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of cAMP." ;
    oboInOwl:hasNarrowSynonym "cAMP chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001463" ;
    a owl:Class ;
    rdfs:label "cAMP chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001053 .

obo:WBPhenotype_0001464
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of cGMP." ;
    oboInOwl:hasNarrowSynonym "cGMP chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001464" ;
    a owl:Class ;
    rdfs:label "cGMP chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001053 .

obo:WBPhenotype_0001465
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of acetone. In C. elegans, at specific concentrations, acetone is an attractant." ;
    oboInOwl:hasNarrowSynonym "acetone chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001465" ;
    a owl:Class ;
    rdfs:label "acetone chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000265 .

obo:WBPhenotype_0001466
    obo:IAO_0000115 "Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWA sensory neuron in control animals." ;
    oboInOwl:hasNarrowSynonym "AWA odorant chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "AWA volatile chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001466" ;
    a owl:Class ;
    rdfs:label "AWA odorant chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000265 .

obo:WBPhenotype_0001467
    obo:IAO_0000115 "Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWC sensory neuron in control animals." ;
    oboInOwl:hasNarrowSynonym "AWC odorant chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "AWC volatile chemotaxis abnormal" ;
    oboInOwl:id "WBPhenotype:0001467" ;
    a owl:Class ;
    rdfs:label "AWC odorant chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000265 .

obo:WBPhenotype_0001468
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of benzaldehyde. In C. elegans, at specific concentrations, benzaldehyde is an attractant." ;
    oboInOwl:hasNarrowSynonym "benzaldehyde chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001468" ;
    a owl:Class ;
    rdfs:label "benzaldehyde chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001467 .

obo:WBPhenotype_0001469
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of butanone. In C. elegans, at specific concentrations, butanone is an attractant." ;
    oboInOwl:hasNarrowSynonym "butanone chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001469" ;
    a owl:Class ;
    rdfs:label "butanone chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001467 .

obo:WBPhenotype_0001470
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of diacetyl. In C. elegans, at specific concentrations, diacetyl is an attractant." ;
    oboInOwl:hasNarrowSynonym "diacetyl chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001470" ;
    a owl:Class ;
    rdfs:label "diacetyl chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001466 .

obo:WBPhenotype_0001471
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of hexanol. In C. elegans, at specific concentrations, hexanol is an attractant." ;
    oboInOwl:hasNarrowSynonym "hexanol chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001471" ;
    a owl:Class ;
    rdfs:label "hexanol chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000265 .

obo:WBPhenotype_0001472
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of isoamyl alcohol. In C. elegans, at specific concentrations, isoamyl alcohol is an attractant." ;
    oboInOwl:hasNarrowSynonym "isoamyl alcohol chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001472" ;
    a owl:Class ;
    rdfs:label "isoamyl alcohol chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001467 .

obo:WBPhenotype_0001473
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanol. In C. elegans, at specific concentrations, pentanol is an attractant." ;
    oboInOwl:hasNarrowSynonym "pentanol chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001473" ;
    a owl:Class ;
    rdfs:label "pentanol chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000265 .

obo:WBPhenotype_0001474
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of pyrazine. In C. elegans, at specific concentrations, pyrazine is an attractant." ;
    oboInOwl:hasNarrowSynonym "pyrazine chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001474" ;
    a owl:Class ;
    rdfs:label "pyrazine chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001466 .

obo:WBPhenotype_0001475
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of trimethylthiazole. In C. elegans, at specific concentrations, trimethylthiazole is an attractant." ;
    oboInOwl:hasNarrowSynonym "trimethylthiazole chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001475" ;
    a owl:Class ;
    rdfs:label "trimethylthiazole chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000265 .

obo:WBPhenotype_0001476
    obo:IAO_0000115 "Any variation in the defecation motor program that involves the contraction of the anterior body wall muscles compared to control." ;
    oboInOwl:hasNarrowSynonym "anterior body contraction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001476" ;
    a owl:Class ;
    rdfs:label "anterior body contraction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000210 .

obo:WBPhenotype_0001477
    obo:IAO_0000115 "Any variation in the directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons, compared to control." ;
    oboInOwl:hasNarrowSynonym "anterograde transport abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001477" ;
    a owl:Class ;
    rdfs:label "anterograde transport variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 .

obo:WBPhenotype_0001478
    obo:IAO_0000115 "Any variation in the elongation of embryonic epidermal cells compared to control. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." ;
    oboInOwl:hasNarrowSynonym "body elongation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001478" ;
    a owl:Class ;
    rdfs:label "body elongation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 .

obo:WBPhenotype_0001479
    obo:IAO_0000115 "Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that induces dauer formation in control animals." ;
    oboInOwl:hasNarrowSynonym "dauer pheromone sensation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001479" ;
    a owl:Class ;
    rdfs:label "dauer pheromone sensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000132, obo:WBPhenotype_0000305, obo:WBPhenotype_0001847 .

obo:WBPhenotype_0001480
    obo:IAO_0000115 "Variations in the rhythmic relaxations of the a highly specialized cuticle region of the pharynx inside the lumen of the second bulb, compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "grinder relaxation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001480" ;
    a owl:Class ;
    rdfs:label "grinder relaxation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000336 .

obo:WBPhenotype_0001481
    obo:IAO_0000115 "The number of body thrashes within an aqueous environment in a given period of time is increased, compared with control worms." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001481" ;
    a owl:Class ;
    rdfs:label "thrashing increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001700 .

obo:WBPhenotype_0001482
    obo:IAO_0000115 "Animals exhibit a reduction in the frequency of oscillations between adjacent body segments from that observed for control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0002330" ;
    oboInOwl:hasExactSynonym "bending frequency reduced", "frequency of sinusoidal movement reduced", "temporal frequency of sinusoidal movement decreased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001482" ;
    a owl:Class ;
    rdfs:label "frequency body bend reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001213, obo:WBPhenotype_0004023 .

obo:WBPhenotype_0001483
    obo:IAO_0000115 "The eggs being deposited by adults are of a later developmental stage, compared to control. In C. elegans, this is likely to be a consequence of delayed active egg-laying periods." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001483" ;
    a owl:Class ;
    rdfs:label "late stage egg laid" ;
    rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0000545 .

obo:WBPhenotype_0001484
    obo:IAO_0000115 "Animals fail to execute directed movement in response to ammonium acetate. In C. elegans, ammonium acetate is an attractant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001484" ;
    a owl:Class ;
    rdfs:label "ammonium acetate chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000265, obo:WBPhenotype_0001441 .

obo:WBPhenotype_0001485
    obo:IAO_0000115 "Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control." ;
    oboInOwl:hasExactSynonym "ER stress response abnormal", "endoplasmic reticulum stress response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001485" ;
    a owl:Class ;
    rdfs:label "ER stress response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0034976
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001486
    obo:IAO_0000115 "Animals accumulate unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001486" ;
    a owl:Class ;
    rdfs:label "unfolded protein accumulation" ;
    rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0001644 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000911
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030968
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001487
    obo:IAO_0000115 "Animals exhibit variations in the development of the male elongated sclerotized structures covered by a hardened layer of cuticle in the tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control." ;
    oboInOwl:hasNarrowSynonym "male spicule development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001487" ;
    a owl:Class ;
    rdfs:label "male spicule development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000430 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005312
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001488
    obo:IAO_0000115 "Animals exhibit variations in the development of the sclerotic cuticle that forms the roof of the proctodeum (gubernaculum) compared to control." ;
    oboInOwl:hasNarrowSynonym "gubernaculum development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001488" ;
    a owl:Class ;
    rdfs:label "gubernaculum development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001367 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0008424
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001489
    obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the sclerotic cuticle that forms the roof of the proctodeum, from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "gubernaculum morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001489" ;
    a owl:Class ;
    rdfs:label "gubernaculum morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001359 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0008424
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001490
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000793 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001490" ;
    a owl:Class ;
    rdfs:label "obsolete posterior region morphology abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0001491
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000792 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001491" ;
    a owl:Class ;
    rdfs:label "obsolete anterior region morphology abnormal" ;
    owl:deprecated true .

obo:WBPhenotype_0001492
    obo:IAO_0000115 "Animals lack a properly developed posterior region compared to control. In C. elegans, mutants exhibit a severely deformed posterior region with a variable knob-like shape; accompanied by arrest at about the time of hatching with fairly normal pharyngeal and anterior development. Most mutants arrest as L1 larvae, and 5% do not hatch." ;
    oboInOwl:hasBroadSynonym "Nob" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001492" ;
    a owl:Class ;
    rdfs:label "no back end" ;
    rdfs:subClassOf obo:WBPhenotype_0000081, obo:WBPhenotype_0000793, obo:WBPhenotype_0000800, obo:WBPhenotype_0000867 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005741
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001493
    obo:IAO_0000115 "VPCs (vulval precursor cells) divide at an earlier stage of development compared to control animals; in C. elegans, VPCs divide in the mid-L3 stage to generate the 22 cells that comprise the vulva." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001493" ;
    a owl:Class ;
    rdfs:label "VPC cell division precocious" ;
    rdfs:subClassOf obo:WBPhenotype_0000345, obo:WBPhenotype_0001495 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000694
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051301
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0007809
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001494
    obo:IAO_0000115 "DTCs migrate at an earlier stage of development, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001494" ;
    a owl:Class ;
    rdfs:label "distal tip cell migration precocious" ;
    rdfs:subClassOf obo:WBPhenotype_0000195, obo:WBPhenotype_0000439 .

obo:WBPhenotype_0001495
    obo:IAO_0000115 "Cells divide at an earlier stage of development compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001495" ;
    a owl:Class ;
    rdfs:label "cell division precocious" ;
    rdfs:subClassOf obo:WBPhenotype_0000439, obo:WBPhenotype_0000746 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000694
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051301
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001496
    obo:IAO_0000115 "Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001214" ;
    oboInOwl:hasExactSynonym "metaphase to anaphase transition fails" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Mat" ;
    oboInOwl:id "WBPhenotype:0001496" ;
    a owl:Class ;
    rdfs:label "metaphase to anaphase transition defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000740 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0031577
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001497
    obo:IAO_0000115 "Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids separate and migrate towards the poles of the spindle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001497" ;
    a owl:Class ;
    rdfs:label "mitotic metaphase to anaphase transition defect" ;
    rdfs:subClassOf obo:WBPhenotype_0001496 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007091
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:CL_0000586
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001498
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the pseudopod of the sperm to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "sperm pseudopod physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001498" ;
    a owl:Class ;
    rdfs:label "sperm pseudopod physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000987 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001912
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0031143
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000050 ;
                                owl:someValuesFrom obo:WBbt_0006798
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001499
    obo:IAO_0000115 "Variations in the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle, compared to control." ;
    oboInOwl:hasNarrowSynonym "meiotic chromosome segregation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001499" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "meiotic chromosome segregation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000773 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0045132
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001500
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanedione." ;
    oboInOwl:hasNarrowSynonym "pentanedione chemotaxis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001500" ;
    a owl:Class ;
    rdfs:label "pentanedione chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001467 .

obo:WBPhenotype_0001501
    obo:IAO_0000115 "Animals fail to discriminate between distinct odorants." ;
    oboInOwl:hasNarrowSynonym "odorant discrimination abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001501" ;
    a owl:Class ;
    rdfs:label "odorant discrimination defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001048 .

obo:WBPhenotype_0001502
    obo:IAO_0000115 "Animals fail to respond to the concentration of a specific chemical that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001502" ;
    a owl:Class ;
    rdfs:label "chemical resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000523 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_24431
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001503
    obo:IAO_0000115 "Any variation in the mechanisms used to ensure that axons in the ventral nerve cord maintain their correct positioning after termination of axonal outgrowth and target recognition compared to control." ;
    oboInOwl:hasNarrowSynonym "ventral nerve cord maintenance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001503" ;
    a owl:Class ;
    rdfs:label "ventral nerve cord maintenance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000515 .

obo:WBPhenotype_0001504
    obo:IAO_0000115 "Sterility caused by aberrant maternal components required for normal postembryonic development and/or function of the germ line." ;
    oboInOwl:hasBroadSynonym "Mes" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001504" ;
    a owl:Class ;
    rdfs:label "maternal effect sterile" ;
    rdfs:subClassOf obo:WBPhenotype_0001037 .

obo:WBPhenotype_0001505
    obo:IAO_0000115 "Any variation in the processes that govern spontaneous backward locomotion compared to control." ;
    oboInOwl:hasNarrowSynonym "spontaneous reversal abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001505" ;
    a owl:Class ;
    rdfs:label "spontaneous reversal variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002320 .

obo:WBPhenotype_0001506
    obo:IAO_0000115 "Any variation in the processes that govern the rate at which spontaneous backward locomotion is initiated compared to control." ;
    oboInOwl:hasNarrowSynonym "spontaneous reversal rate abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001506" ;
    a owl:Class ;
    rdfs:label "spontaneous reversal rate variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001505 .

obo:WBPhenotype_0001507
    obo:IAO_0000115 "Animals fail to be affected by toxins produced by Bacillus thuringiensis (Bt toxins) in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001507" ;
    a owl:Class ;
    rdfs:label "Bacillus thuringiensis toxin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 .

obo:WBPhenotype_0001508
    obo:IAO_0000115 "Any perturbation that disrupts the fusion between the anchor cell and the surrounding utse syncytium. Such variations result in the loss of uterine-vulval connectivity and continuity." ;
    oboInOwl:hasNarrowSynonym "anchor cell fusion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001508" ;
    a owl:Class ;
    rdfs:label "anchor cell fusion defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000165, obo:WBPhenotype_0000283 .

obo:WBPhenotype_0001509
    obo:IAO_0000115 "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are absent." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000407" ;
    oboInOwl:hasExactSynonym "ray loss" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001509" ;
    a owl:Class ;
    rdfs:label "rays missing" ;
    rdfs:subClassOf obo:WBPhenotype_0000199, obo:WBPhenotype_0000505, obo:WBPhenotype_0002174 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006941
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001510
    obo:IAO_0000115 "Any variation in the processes that govern acquisition of neuronal cell fates compared to control." ;
    oboInOwl:hasNarrowSynonym "neuronal cell fate specification abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001510" ;
    a owl:Class ;
    rdfs:label "neuronal cell fate specification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000216, obo:WBPhenotype_0000816 .

obo:WBPhenotype_0001511
    obo:IAO_0000115 "Variations in the stereotypical migration pattern of the linker cell in a developing male compared to control." ;
    oboInOwl:hasNarrowSynonym "linker cell migration abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001511" ;
    a owl:Class ;
    rdfs:label "linker cell migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000594 .

obo:WBPhenotype_0001512
    obo:IAO_0000115 "Bilaterally symmetric cell fail to acquire specific left-right asymmetric properties such as L/R specific cell position, cell death or gene expression." ;
    oboInOwl:hasBroadSynonym "Lsy" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001512" ;
    a owl:Class ;
    rdfs:label "loss of left right asymmetry" ;
    rdfs:subClassOf obo:WBPhenotype_0000216 .

obo:WBPhenotype_0001513
    obo:IAO_0000115 "Variations in the process of secretion of a class of membrane-bound vesicles found inside neurons, gland cells, and some epithelial cells in which the central core appears darkly stained when viewed in thin section by electron microscopy, compared to control. Exocytosis occurs via the fusion of the vesicle with the plasma membrane of a cell (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "dense core vesicle exocytosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001513" ;
    a owl:Class ;
    rdfs:label "dense core vesicle exocytosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000728 .

obo:WBPhenotype_0001514
    obo:IAO_0000115 "Variations in the uptake of a small membrane-bound organelle, filled with neurotransmitter(s) and/or neuropeptides, by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle compared to control(Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "synaptic vesicle endocytosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001514" ;
    a owl:Class ;
    rdfs:label "synaptic vesicle endocytosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001422, obo:WBPhenotype_0001684 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048488
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001515
    obo:IAO_0000115 "Animals exhibit variations in the quantity or patterning of electron-dense columnar structures that join the basal and cortical cuticle layers, from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "struts abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001515" ;
    a owl:Class ;
    rdfs:label "struts variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000948 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060109
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001516
    obo:IAO_0000115 "Animals exhibit a helically twisted cuticle. In practice the degree of twisting is measured as the number of helical twists the alae make about anterior/posterior axis of the animal." ;
    oboInOwl:hasNarrowSynonym "cuticle helicity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001516" ;
    a owl:Class ;
    rdfs:label "helical cuticle" ;
    rdfs:subClassOf obo:WBPhenotype_0000948 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000404
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005755
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001517
    obo:IAO_0000115 "Animals exhibit variations in the circumferential pattern of ridges in the outer cortical layer of the cuticle, compared to that observed in control animals of the same developmental stage." ;
    oboInOwl:hasNarrowSynonym "annulae morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001517" ;
    a owl:Class ;
    rdfs:label "annulae morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000948 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0060107
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001518
    obo:IAO_0000115 "Any variation in the levels and/or localization of biogenic amines compared to control animals." ;
    oboInOwl:hasBroadSynonym "FIF" ;
    oboInOwl:hasNarrowSynonym "biogenic amine physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Formaldehyde induced fluorescence abnormal" ;
    oboInOwl:id "WBPhenotype:0001518" ;
    a owl:Class ;
    rdfs:label "biogenic amine physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0001519
    obo:IAO_0000115 "Any variation in the orderly movement of cells along the posterior axis of the animal (abolished, misdirected or incomplete) compared to control." ;
    oboInOwl:hasNarrowSynonym "abnormal posterior cell migration" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001519" ;
    a owl:Class ;
    rdfs:label "posterior cell migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000594 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001633
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:GO_0016477
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001520
    obo:IAO_0000115 "Any variation in the orderly movement of neurons along the posterior axis of the animal(abolished, misdirected or incomplete) compared to control." ;
    oboInOwl:hasNarrowSynonym "abnormal posterior neuron migration" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001520" ;
    a owl:Class ;
    rdfs:label "posterior neuron migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001140 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001633
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:GO_0001764
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001521
    obo:IAO_0000115 "Embryos retract after the embryonic elongation process." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001521" ;
    a owl:Class ;
    rdfs:label "body elongation retracted" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 .

obo:WBPhenotype_0001522
    obo:IAO_0000115 "The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) constitutively extend into the external environment through the cloacal opening. In C. elegans males there are two copulatory spicules." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001522" ;
    a owl:Class ;
    rdfs:label "spicules protrude" ;
    rdfs:subClassOf obo:WBPhenotype_0000908 .

obo:WBPhenotype_0001523
    obo:IAO_0000115 "Any variation in the makeup, density or area of the ECM compared to control." ;
    oboInOwl:hasNarrowSynonym "extracellular matrix abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001523" ;
    a owl:Class ;
    rdfs:label "extracellular matrix variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000912 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0031012
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001524
    obo:IAO_0000115 "Exhibition of quiescent behavior under inappropriate conditions and improper recovery from quiescent state. Quiescent behavior is normally coupled with lethargus." ;
    oboInOwl:hasNarrowSynonym "quiescence abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "narcoleptic" ;
    oboInOwl:id "WBPhenotype:0001524" ;
    a owl:Class ;
    rdfs:label "quiescence variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 .

obo:WBPhenotype_0001525
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the posterior region of the pharynx compared to control." ;
    oboInOwl:hasNarrowSynonym "terminal bulb morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001525" ;
    a owl:Class ;
    rdfs:label "terminal bulb morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000709 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003732
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001526
    obo:IAO_0000115 "Animals exhibit variations in the structure or organization of any one of the specialized sensory receptor cells of the nervous system that compared to control animals. In C. elegans, these specialized cells are characterized as having axoneme containing dendritic projections emanating from their cell body." ;
    oboInOwl:hasNarrowSynonym "ciliated neuron morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001526" ;
    a owl:Class ;
    rdfs:comment "WBbt:0006816." ;
    rdfs:label "ciliated neuron morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000299 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006816
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001527
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head or along the tail, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "amphid phasmid sensillum morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001527" ;
    a owl:Class ;
    rdfs:comment "WBbt:0005391." ;
    rdfs:label "amphid phasmid sensillum morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000299 .

obo:WBPhenotype_0001528
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of any component of the sensillum channel including the sheath and or socket cells, their junctions with each other, channel neurons or surrounding epithelia compared to control." ;
    oboInOwl:hasNarrowSynonym "sensillum accessory cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001528" ;
    a owl:Class ;
    rdfs:label "sensillum accessory cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000299 .

obo:WBPhenotype_0001529
    obo:IAO_0000115 "OBSOLETE: Any variation in the form, structure or composition of an interfacial epithelial cell which forms a specialized environment surrounding the ciliated sensory ending(s) of one or more neurons and is often accompanied by a more distal socket cell compared to control (Wormatlas)." ;
    obo:IAO_0100001 obo:WBPhenotype_0000972 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001529" ;
    a owl:Class ;
    rdfs:label "obsolete sensilium sheath cell variant" ;
    owl:deprecated true .

obo:WBPhenotype_0001530
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake." ;
    oboInOwl:hasNarrowSynonym "cephalic sensillum morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001530" ;
    a owl:Class ;
    rdfs:comment "WBbt:0006920." ;
    rdfs:label "cephalic sensillum morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000299 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006920
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001531
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth." ;
    oboInOwl:hasNarrowSynonym "labial sensillum morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001531" ;
    a owl:Class ;
    rdfs:label "labial sensillum morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000299 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005107
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001532
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2." ;
    oboInOwl:hasNarrowSynonym "inner labial morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001532" ;
    a owl:Class ;
    rdfs:label "inner labial morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001531 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005116
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001533
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum." ;
    oboInOwl:hasNarrowSynonym "outer labial morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001533" ;
    a owl:Class ;
    rdfs:label "outer labial morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001531 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005501
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001534
    obo:IAO_0000115 "Any variation in makeup, density or area of the ECM lending structure to neurons compared to control animals. In C. elegans, the neuronal ECM is sometimes referred to as a mantle." ;
    oboInOwl:hasNarrowSynonym "neuronal ECM abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001534" ;
    a owl:Class ;
    rdfs:label "neuronal ECM variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001523 .

obo:WBPhenotype_0001535
    obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC." ;
    oboInOwl:hasNarrowSynonym "deirid sensillum morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001535" ;
    a owl:Class ;
    rdfs:label "deirid sensillum morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000299 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006926
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001536
    obo:IAO_0000115 "Embryos exhibit variations in the patterning of differentiated cell types, compared to control." ;
    oboInOwl:hasNarrowSynonym "embryonic cell patterning abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001536" ;
    a owl:Class ;
    rdfs:label "embryonic cell patterning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000050 .

obo:WBPhenotype_0001537
    obo:IAO_0000115 "Any variation in the ability of cells to monitor the quality of their mRNAs and degrade any transcripts that are poorly or incompletely translated compared to control." ;
    oboInOwl:hasNarrowSynonym "mRNA turnover abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001537" ;
    a owl:Class ;
    rdfs:label "mRNA surveillance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000028 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0071028
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001538
    obo:IAO_0000115 "Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia." ;
    oboInOwl:hasNarrowSynonym "Smg" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001538" ;
    a owl:Class ;
    rdfs:label "mRNA surveillance defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000028 .

obo:WBPhenotype_0001539
    obo:IAO_0000115 "Animals exhibit variations in the entry into the dauer stage when exposed to conditions that induce dauer formation in control animals." ;
    oboInOwl:hasNarrowSynonym "dauer induction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001539" ;
    a owl:Class ;
    rdfs:label "dauer induction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000308 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043053
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001540
    obo:IAO_0000115 "The life span of dauer-staged animals is either longer or shorter than that observed in control dauer animals." ;
    oboInOwl:hasNarrowSynonym "dauer lifespan abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001540" ;
    a owl:Class ;
    rdfs:label "dauer lifespan variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001547 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000050
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001541
    obo:IAO_0000115 "Variations in the execution of the developmentally-regulated cell cycle arrest in the gonad during the dauer stage, compared to control." ;
    oboInOwl:hasNarrowSynonym "dauer gonad arrest abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001541" ;
    a owl:Class ;
    rdfs:label "dauer gonad arrest variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000637 .

obo:WBPhenotype_0001542
    obo:IAO_0000115 "Any variation in the inhibition of feeding which is induced/occurs during the dauer stage compared to control." ;
    oboInOwl:hasNarrowSynonym "dauer feeding suppressed abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001542" ;
    a owl:Class ;
    rdfs:label "dauer feeding suppressed variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001001 .

obo:WBPhenotype_0001543
    obo:IAO_0000115 "Dauer stage animals exhibit a decrease in self-propelled movement on a solid medium compared to control animals." ;
    oboInOwl:hasNarrowSynonym "dauer reduced locomotion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001543" ;
    a owl:Class ;
    rdfs:label "dauer reduced locomotion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001001 .

obo:WBPhenotype_0001544
    obo:IAO_0000115 "Variations in the state or activity of a dauer stage organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus, compared to control." ;
    oboInOwl:hasNarrowSynonym "dauer sensory response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001544" ;
    a owl:Class ;
    rdfs:label "dauer sensory response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001001 .

obo:WBPhenotype_0001545
    obo:IAO_0000115 "Any variation in the overall structure or appearance of an animal progressing through an alternative larval stage in response to environmental stresses compared to control animals." ;
    oboInOwl:hasNarrowSynonym "dauer body morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001545" ;
    a owl:Class ;
    rdfs:label "dauer body morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000934 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001546
    obo:IAO_0000115 "Variations which lead to the decreased ability of dauer larva to survive at extreme conditions, such as high or low temperatures, the presence of dilute acids, detergents, anesthetics, or even fixatives, compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "dauer resistance to harsh conditions abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001546" ;
    a owl:Class ;
    rdfs:label "dauer resistance to harsh conditions variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002527 .

obo:WBPhenotype_0001547
    obo:IAO_0000115 "Animals exhibit variations in the chemical reactions and pathways that occur during the dauer life stage, compared to control." ;
    oboInOwl:hasExactSynonym "dauer metabolism abnormal", "dauer metabolism variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001547" ;
    a owl:Class ;
    rdfs:label "dauer metabolism phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0002527 .

obo:WBPhenotype_0001548
    obo:IAO_0000115 "Any variation in the ratio of the body length to body width in a dauer stage animal, compared to control. Long thin animals will have a high axial ratio." ;
    oboInOwl:hasNarrowSynonym "dauer axial ratio abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001548" ;
    a owl:Class ;
    rdfs:label "dauer axial ratio variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001545 .

obo:WBPhenotype_0001549
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion." ;
    oboInOwl:hasNarrowSynonym "dauer gut abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001549" ;
    a owl:Class ;
    rdfs:label "dauer gut variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001545 .

obo:WBPhenotype_0001550
    obo:IAO_0000115 "Variations in the form or composition of the cuticle-lined lumenal region which lies just behind the lips at the entrance to the pharyngeal lumen in dauer stage animals compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "dauer buccal cavity morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001550" ;
    a owl:Class ;
    rdfs:label "dauer buccal cavity morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001545 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005255
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001551
    obo:IAO_0000115 "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) during the dauer larva stage, compared to control animals (Wormatlas). The dauer larval stage is a developmentally arrested larval stage that is specialized for survival under harsh, or otherwise unfavorable environmental conditions." ;
    oboInOwl:hasNarrowSynonym "dauer cuticle abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001551" ;
    a owl:Class ;
    rdfs:label "dauer cuticle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001545 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005755
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001552
    obo:IAO_0000115 "Variations in the form or composition of the mouthparts at the anterior end of the digestive tract during the dauer stage, compared to control." ;
    oboInOwl:hasNarrowSynonym "dauer pharynx morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001552" ;
    a owl:Class ;
    rdfs:label "dauer pharynx morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001545 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003681
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001553
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "dauer excretory gland abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001553" ;
    a owl:Class ;
    rdfs:label "dauer excretory gland variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001545 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005776
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001554
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control." ;
    oboInOwl:hasNarrowSynonym "dauer nose morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001554" ;
    a owl:Class ;
    rdfs:label "dauer nose morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001545 .

obo:WBPhenotype_0001555
    obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the dauer sensory system, compared to control. The dauer sensory system is used to perceive the physical and chemical environment during the dauer larval stage." ;
    oboInOwl:hasNarrowSynonym "dauer sensory system morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001555" ;
    a owl:Class ;
    rdfs:label "dauer sensory system morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001545 .

obo:WBPhenotype_0001556
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "dauer sensillum abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001556" ;
    a owl:Class ;
    rdfs:label "dauer sensillum variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001555 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006929
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001557
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth." ;
    oboInOwl:hasNarrowSynonym "dauer labial sensillum abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001557" ;
    a owl:Class ;
    rdfs:label "dauer labial sensillum variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001556 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005107
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001558
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "dauer amphid sensillum abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001558" ;
    a owl:Class ;
    rdfs:label "dauer amphid sensillum variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001556 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005391
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001559
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC." ;
    oboInOwl:hasNarrowSynonym "dauer deirid sensillum abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001559" ;
    a owl:Class ;
    rdfs:label "dauer deirid sensillum variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001556 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006926
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001560
    obo:IAO_0000115 "OBSOLETE." ;
    oboInOwl:consider obo:WBPhenotype_0001550 ;
    oboInOwl:hasNarrowSynonym "dauer sensory system plug abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001560" ;
    a owl:Class ;
    rdfs:label "obsolete dauer sensory system plug variant" ;
    owl:deprecated true .

obo:WBPhenotype_0001561
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2." ;
    oboInOwl:hasNarrowSynonym "dauer inner labial sensillum abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001561" ;
    a owl:Class ;
    rdfs:label "dauer inner labial sensillum variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001557 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005116
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001562
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum." ;
    oboInOwl:hasNarrowSynonym "dauer outer labial sensillum abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001562" ;
    a owl:Class ;
    rdfs:label "dauer outer labial sensillum variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001557 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005501
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001563
    obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake." ;
    oboInOwl:hasNarrowSynonym "dauer cephalic sensillum abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001563" ;
    a owl:Class ;
    rdfs:label "dauer cephalic sensillum variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001556 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006920
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during> ;
                    owl:someValuesFrom obo:WBls_0000032
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001564
    obo:IAO_0000115 "The window of production of self-fertilized eggs exceeds or does not extend to the same length as control." ;
    oboInOwl:hasNarrowSynonym "duration of self fertility abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001564" ;
    a owl:Class ;
    rdfs:label "duration of self fertility variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000806 .

obo:WBPhenotype_0001565
    obo:IAO_0000115 "Failure to execute characteristic response to lysine as defined by control animals. In C. elegans, lysine is an attractant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001565" ;
    a owl:Class ;
    rdfs:label "lysine chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001441 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050918
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty <http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to> ;
                    owl:someValuesFrom obo:CHEBI_25094
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001566
    obo:IAO_0000115 "Any variation in the process that regulates the migration of ventral epidermal cells toward the ventral midline (to encase underlying cells in an epithelial monolayer) in developing embryos compared to control." ;
    oboInOwl:hasNarrowSynonym "ventral enclosure abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001566" ;
    a owl:Class ;
    rdfs:label "ventral enclosure variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 .

obo:WBPhenotype_0001567
    obo:IAO_0000115 "Nuclei of specific cells are larger compared to control animals." ;
    oboInOwl:hasExactSynonym "nuclear size increased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001567" ;
    a owl:Class ;
    rdfs:label "nuclei enlarged" ;
    rdfs:subClassOf obo:WBPhenotype_0002607 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000586
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005634
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001568
    obo:IAO_0000115 "Any variation in the export of mRNA from the cell nucleus compared to control." ;
    oboInOwl:hasNarrowSynonym "mRNA export abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001568" ;
    a owl:Class ;
    rdfs:label "mRNA export variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000114, obo:WBPhenotype_0001706 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006406
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001569
    obo:IAO_0000115 "The characteristic organization of myosin filaments into discrete A-bands within the muscle cells is disrupted. In C. elegans, myosin filaments no longer appear as continuous longitudinally oriented fibers across the muscle quadrants." ;
    oboInOwl:hasNarrowSynonym "body wall muscle myosin organization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Dim", "body wall muscle thick myofilament organization abnormal" ;
    oboInOwl:id "WBPhenotype:0001569" ;
    a owl:Class ;
    rdfs:label "body wall muscle myosin organization defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000782 .

obo:WBPhenotype_0001570
    obo:IAO_0000115 "The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants." ;
    oboInOwl:hasNarrowSynonym "body wall muscle actin organization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "body wall muscle thin myofilament organization abnormal" ;
    oboInOwl:id "WBPhenotype:0001570" ;
    a owl:Class ;
    rdfs:label "body wall muscle actin organization defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000781 .

obo:WBPhenotype_0001571
    obo:IAO_0000115 "Variations in the accumulation of muscle proteins at membranes where adjacent muscle cells contact each other and the hypodermis compared to control. In C. elegans, during early embryonic body wall muscle development, muscle, basement membrane, and hypodermal components are all colocalized in a continuous linear structure at the site of muscle-hypodermal contact." ;
    oboInOwl:hasNarrowSynonym "body wall muscle cell polarization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001571" ;
    a owl:Class ;
    rdfs:label "body wall muscle cell polarization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000926 .

obo:WBPhenotype_0001572
    obo:IAO_0000115 "Animals that are not ordinarily male, exhibit male-specific attributes. In C. elegans, XX animals exhibit male-specific attributes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001572" ;
    a owl:Class ;
    rdfs:label "masculinized" ;
    rdfs:subClassOf obo:WBPhenotype_0001022 .

obo:WBPhenotype_0001573
    obo:IAO_0000115 "Animals exhibit variations in the response to the addition of nicotine compared to that observed in control animals. Nicotine is a cholinergic agonist." ;
    oboInOwl:hasNarrowSynonym "nicotine response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001573" ;
    a owl:Class ;
    rdfs:label "nicotine response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0001574
    obo:IAO_0000115 "Animals exhibit variations in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." ;
    oboInOwl:hasNarrowSynonym "ATP levels abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001574" ;
    a owl:Class ;
    rdfs:label "ATP levels variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_15422
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001575
    obo:IAO_0000115 "Animals exhibit a decrease in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001575" ;
    a owl:Class ;
    rdfs:label "ATP levels reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001574 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_15422
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001576
    obo:IAO_0000115 "Variations in the spatial distribution of the mitochondria within the cell compared to control." ;
    oboInOwl:hasNarrowSynonym "mitochondria spacing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001576" ;
    a owl:Class ;
    rdfs:label "mitochondria spacing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001401, obo:WBPhenotype_0002098 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000140
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005739
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001577
    obo:IAO_0000115 "Animals exhibit variations in the parallel arrangement of mitochondria within a cell compared to control." ;
    oboInOwl:hasNarrowSynonym "mitochondria alignment abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001577" ;
    a owl:Class ;
    rdfs:label "mitochondria alignment variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001401, obo:WBPhenotype_0002098 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001652
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:GO_0005739
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005739
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001578
    obo:IAO_0000115 "Animals fail to respond to the concentration of cholinergic agonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001578" ;
    a owl:Class ;
    rdfs:label "cholinergic agonist resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_38324
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001579
    obo:IAO_0000115 "Animals respond to a cholinergic agonist at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001579" ;
    a owl:Class ;
    rdfs:label "cholinergic agonist hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_38324
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001580
    obo:IAO_0000115 "Any variation in the progression of the controlled breakdown of the nuclear envelope, compared to control." ;
    oboInOwl:hasNarrowSynonym "nuclear envelope breakdown abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001580" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "nuclear envelope breakdown variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002037 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051081
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001581
    obo:IAO_0000115 "Levels of transcripts associated with genes on the X chromosome are increased compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001581" ;
    a owl:Class ;
    rdfs:label "X linked gene expression enhanced" ;
    rdfs:subClassOf obo:WBPhenotype_0000718 .

obo:WBPhenotype_0001582
    obo:IAO_0000115 "Levels of transcripts associated with genes on the X chromosome are decreased compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001582" ;
    a owl:Class ;
    rdfs:label "X linked gene expression reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000718 .

obo:WBPhenotype_0001583
    obo:IAO_0000115 "Animals segregate progeny with 3 X chromosomes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001583" ;
    a owl:Class ;
    rdfs:label "XXX progeny" ;
    rdfs:subClassOf obo:WBPhenotype_0001664 .

obo:WBPhenotype_0001584
    obo:IAO_0000115 "Any variation in the movement of chromosomes to the spindle equator during mitosis compared to control animals." ;
    oboInOwl:hasNarrowSynonym "chromosome alignment at metaphase plate abnormal", "chromosome alignment at metaphase plate variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "chromosome congression" ;
    oboInOwl:id "WBPhenotype:0001584" ;
    a owl:Class ;
    rdfs:label "chromosome alignment variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000773 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051310
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001585
    obo:IAO_0000115 "Any variation in a cell's ability to divide asymmetrically to produce two daughter cells with different developmental potentials compared to control." ;
    oboInOwl:hasNarrowSynonym "asymmetric cell division abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001585" ;
    a owl:Class ;
    rdfs:label "asymmetric cell division variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001235 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008356
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001586
    obo:IAO_0000115 "Animals contain more than one anchor cell. In C. elegans, presumptive ventral uterine cells undergo fate transformation and instead acquire the properties of an anchor cell (often due to defects in lateral signaling)." ;
    oboInOwl:hasNarrowSynonym "double anchor cell" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001586" ;
    a owl:Class ;
    rdfs:label "multiple anchor cells" ;
    rdfs:subClassOf obo:WBPhenotype_0002175 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004522
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001587
    obo:IAO_0000115 "Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas)." ;
    oboInOwl:hasExactSynonym "actin organization biogenesis variant" ;
    oboInOwl:hasNarrowSynonym "actin organization biogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001587" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "actin organization biogenesis phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0001345 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030036
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001588
    obo:IAO_0000115 "Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "microtubule organization biogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001588" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "microtubule organization biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001345 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000226
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001589
    obo:IAO_0000115 "Any variation that alters the characteristic de novo formation of a microtubule compared to control." ;
    oboInOwl:hasNarrowSynonym "microtubule nucleation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001589" ;
    a owl:Class ;
    rdfs:label "microtubule nucleation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001588 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007020
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001590
    obo:IAO_0000115 "Any variation that alters the characteristic removal of tubulin heterodimers from one or both ends of a microtubule compared to control." ;
    oboInOwl:hasNarrowSynonym "microtubule depolymerization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001590" ;
    a owl:Class ;
    rdfs:label "microtubule depolymerization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001588 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007019
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001591
    obo:IAO_0000115 "Any variation that alters the characteristic addition of tubulin heterodimers to one or both ends of a microtubule compared to control." ;
    oboInOwl:hasNarrowSynonym "microtubule polymerization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001591" ;
    a owl:Class ;
    rdfs:label "microtubule polymerization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001588 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0046785
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001592
    obo:IAO_0000115 "Alternating periods of stopping and moving; Motion is interrupted by periods of inactivity lasting several seconds." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001592" ;
    a owl:Class ;
    rdfs:label "fainter" ;
    rdfs:subClassOf obo:WBPhenotype_0002308 .

obo:WBPhenotype_0001593
    obo:IAO_0000115 "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control. In C. elegans this silencing occurs only in the germline." ;
    oboInOwl:hasNarrowSynonym "transgene silencing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001593" ;
    a owl:Class ;
    rdfs:label "transgene silencing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002063 .

obo:WBPhenotype_0001594
    obo:IAO_0000115 "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the germline, compared to control." ;
    oboInOwl:hasNarrowSynonym "germline transgene silencing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001594" ;
    a owl:Class ;
    rdfs:label "germline transgene silencing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001593 .

obo:WBPhenotype_0001595
    obo:IAO_0000115 "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the soma, compared to control." ;
    oboInOwl:hasNarrowSynonym "somatic transgene silencing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001595" ;
    a owl:Class ;
    rdfs:label "somatic transgene silencing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001593 .

obo:WBPhenotype_0001596
    obo:IAO_0000115 "Swelling of the tail hypodermis resulting in a prematurely-truncated and thickened appearance of the tail. In C. elegans, this is usually applies to hermaphrodites." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001596" ;
    a owl:Class ;
    rdfs:label "tail bobbed" ;
    rdfs:subClassOf obo:WBPhenotype_0000073 .

obo:WBPhenotype_0001597
    obo:IAO_0000115 "Any variation that results in a fewer than control number of muscle cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001597" ;
    a owl:Class ;
    rdfs:label "muscle missing" ;
    rdfs:subClassOf obo:WBPhenotype_0000622, obo:WBPhenotype_0002174 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003675
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001598
    obo:IAO_0000115 "Treatment with inhibitors of serotonin reuptake does not elicit the same response as observed for control animals." ;
    oboInOwl:hasNarrowSynonym "inhibitor of serotonin uptake abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001598" ;
    a owl:Class ;
    rdfs:label "inhibitor of serotonin uptake variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0001599
    obo:IAO_0000115 "Animals fail to respond to the concentration of ouabain that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, resistance to ouabain is often assayed via body contraction response." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001599" ;
    a owl:Class ;
    rdfs:label "ouabain resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000331 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_472805
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001600
    obo:IAO_0000115 "Animals require increased concentration or longer exposure to ouabain to elicit the rapid muscular contractions seen in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001600" ;
    a owl:Class ;
    rdfs:label "contraction response to ouabain resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001599 .

obo:WBPhenotype_0001601
    obo:IAO_0000115 "Animals fail to respond to the concentration of biogenic amine receptor antagonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasNarrowSynonym "serotonin receptor antagonist" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001601" ;
    a owl:Class ;
    rdfs:label "biogenic amine receptor antagonist resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 .

obo:WBPhenotype_0001602
    obo:IAO_0000115 "Animals fail to respond to the concentration of methiothepin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001602" ;
    a owl:Class ;
    rdfs:label "methiothepin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001601 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_64203
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001603
    obo:IAO_0000115 "Animals fail to respond to the concentration of cyproheptadine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001603" ;
    a owl:Class ;
    rdfs:label "cyproheptadine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001601 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_4046
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001604
    obo:IAO_0000115 "Animals fail to respond to the concentration of mianserin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "dibenzazepine resistant" ;
    oboInOwl:id "WBPhenotype:0001604" ;
    a owl:Class ;
    rdfs:label "mianserin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001601 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_51137
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001605
    obo:IAO_0000115 "Animals do not live longer in response to mianserin compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001605" ;
    a owl:Class ;
    rdfs:label "extended life span response to mianserin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001604 .

obo:WBPhenotype_0001606
    obo:IAO_0000115 "Animals respond to ethanol at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasBroadSynonym "alcohol sensitive" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001606" ;
    a owl:Class ;
    rdfs:label "ethanol hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000008 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_16236
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001607
    obo:IAO_0000115 "Animals become paralyzed in response to ethanol at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001607" ;
    a owl:Class ;
    rdfs:label "paralysis response to ethanol hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001606 .

obo:WBPhenotype_0001608
    obo:IAO_0000115 "Animals respond to the anesthetic enflurane at lower concentrations or shorter exposure times than control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ether hypersensitive" ;
    oboInOwl:id "WBPhenotype:0001608" ;
    a owl:Class ;
    rdfs:label "enflurane hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000008 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_4792
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001609
    obo:IAO_0000115 "Animals respond to the anesthetic isoflurane at lower concentrations or shorter response times than control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ether hypersensitive" ;
    oboInOwl:id "WBPhenotype:0001609" ;
    a owl:Class ;
    rdfs:label "isoflurane hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000008 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_6015
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001610
    obo:IAO_0000115 "Animals respond to the anesthetic ether at lower concentrations or shorter response times than control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ether hypersensitive" ;
    oboInOwl:id "WBPhenotype:0001610" ;
    a owl:Class ;
    rdfs:label "diethyl ether hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000008 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_35702
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001611
    obo:IAO_0000115 "Animals respond to the lipid-soluble anesthetic halothane at lower concentrations or shorter response times compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001611" ;
    a owl:Class ;
    rdfs:label "halothane hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000008 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_5615
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001612
    obo:IAO_0000115 "Animals fail to respond to the concentration of ethanol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to ethanol to elicit the response compared to control animals. In C.elegans the phenotype designation Jud is short for JUDang, which is Korean for resistant to alcohol." ;
    oboInOwl:hasBroadSynonym "Jud", "alcohol resistant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001612" ;
    a owl:Class ;
    rdfs:label "ethanol resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000009 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_16236
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001613
    obo:IAO_0000115 "Animals in the presence of ethanol continue to respond to touch under conditions when control worms have stopped responding to stimuli." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001613" ;
    a owl:Class ;
    rdfs:label "paralysis response to ethanol resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001612 .

obo:WBPhenotype_0001614
    obo:IAO_0000115 "Animals exhibit variations in their response to a specific anticonvulsant compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "anticonvulsant response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001614" ;
    a owl:Class ;
    rdfs:label "anticonvulsant response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0001615
    obo:IAO_0000115 "Animals fail to respond to the concentration of compounds that act as anticonvulsants that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001615" ;
    a owl:Class ;
    rdfs:label "anticonvulsant resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001614 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_35623
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001616
    obo:IAO_0000115 "Animals fail to respond to the concentration of trimethadione, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001616" ;
    a owl:Class ;
    rdfs:label "trimethadione resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001615 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_9727
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001617
    obo:IAO_0000115 "Animals fail to respond to the concentration of ethosuximide, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001617" ;
    a owl:Class ;
    rdfs:label "ethosuximide resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001615 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_4887
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001618
    obo:IAO_0000115 "Animals fail to respond to the concentration of the anesthetic halothane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001618" ;
    a owl:Class ;
    rdfs:label "halothane resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000009 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_5615
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001619
    obo:IAO_0000115 "Animals fail to respond to the concentration of the volatile anesthetic isoflurane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001619" ;
    a owl:Class ;
    rdfs:label "isoflurane resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000009 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_6015
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001620
    obo:IAO_0000115 "Animals exhibit variations in their response to oxidative stress compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "organism oxidative stress response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001620" ;
    a owl:Class ;
    rdfs:label "organism oxidative stress response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006979
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001621
    obo:IAO_0000115 "Animals respond to a lower concentration of reactive oxygen species or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001621" ;
    a owl:Class ;
    rdfs:label "organism oxidative stress response hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001620 .

obo:WBPhenotype_0001622
    obo:IAO_0000115 "Animals lay eggs at a greater rate in response to exogenous serotonin compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001622" ;
    a owl:Class ;
    rdfs:label "egg laying serotonin hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000023, obo:WBPhenotype_0001629 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001551
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_28790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001623
    obo:IAO_0000115 "Any variation in the posture of the male tail after application of exogenous serotonin compared to control. In C. elegans, males respond with a tight ventral curling of the male tail in response to serotonin." ;
    oboInOwl:hasNarrowSynonym "male tail curling serotonin abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001623" ;
    a owl:Class ;
    rdfs:label "male tail curling serotonin variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001232 .

obo:WBPhenotype_0001624
    obo:IAO_0000115 "Animals fail to respond to the concentration of serotonin that elicits a male tail curling response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001624" ;
    a owl:Class ;
    rdfs:label "male tail curling serotonin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001623 .

obo:WBPhenotype_0001625
    obo:IAO_0000115 "Males respond to serotonin by curling their tails at a lower concentration or a shorter exposure compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001625" ;
    a owl:Class ;
    rdfs:label "male tail curling serotonin hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000023, obo:WBPhenotype_0001623 .

obo:WBPhenotype_0001626
    obo:IAO_0000115 "Any variation in the locomotion rate after application of exogenous serotonin compared to control." ;
    oboInOwl:hasNarrowSynonym "locomotion rate serotonin abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001626" ;
    a owl:Class ;
    rdfs:label "locomotion rate serotonin variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001232 .

obo:WBPhenotype_0001627
    obo:IAO_0000115 "The decrease in locomotion rate in the presence of serotonin is greater than control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "locomotion rate serotonin reduced" ;
    oboInOwl:id "WBPhenotype:0001627" ;
    a owl:Class ;
    rdfs:label "locomotion rate serotonin hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000023, obo:WBPhenotype_0001626 .

obo:WBPhenotype_0001628
    obo:IAO_0000115 "Animals fail to decrease their locomotion rate in response the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "locomotion rate serotonin increased" ;
    oboInOwl:id "WBPhenotype:0001628" ;
    a owl:Class ;
    rdfs:label "locomotion rate serotonin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001626 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001551
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_28790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007626
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001629
    obo:IAO_0000115 "Any variation in egg laying behavior after application of exogenous serotonin compared to control. In C. elegans, serotonin induces egg laying." ;
    oboInOwl:hasNarrowSynonym "egg laying serotonin abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001629" ;
    a owl:Class ;
    rdfs:label "egg laying serotonin variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001101, obo:WBPhenotype_0001232 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001457
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_28790
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0018991
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001630
    obo:IAO_0000115 "Any variation in the developmental progression of the intestine that leads to a blockage in the alimentary canal." ;
    oboInOwl:hasBroadSynonym "Gob" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001630" ;
    a owl:Class ;
    rdfs:label "gut obstructed" ;
    rdfs:subClassOf obo:WBPhenotype_0000708 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001819
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005772
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001631
    obo:IAO_0000115 "Animals produce ova/sperm that contain no X chromosome in a nonmendelian segregation pattern." ;
    oboInOwl:hasNarrowSynonym "nullo X gamete abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001631" ;
    a owl:Class ;
    rdfs:label "nullo X gamete" ;
    rdfs:subClassOf obo:WBPhenotype_0001664 .

obo:WBPhenotype_0001632
    obo:IAO_0000115 "Animals produce ova/sperm that contain 2 X chromosomes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001632" ;
    a owl:Class ;
    rdfs:label "diplo X gamete" ;
    rdfs:subClassOf obo:WBPhenotype_0001664 .

obo:WBPhenotype_0001633
    obo:IAO_0000115 "Animals produce ova/sperm that contain lethal factors as a result of chromosomal disjunction defects." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001633" ;
    a owl:Class ;
    rdfs:label "lethal gamete" ;
    rdfs:subClassOf obo:WBPhenotype_0001174 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000718
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CL_0000300
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001634
    obo:IAO_0000115 "Animals respond to compounds that elicit electrophilic stress at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001634" ;
    a owl:Class ;
    rdfs:label "organism electrophilic stress hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 .

obo:WBPhenotype_0001635
    obo:IAO_0000115 "Animals contain an excess number of pharyngeal cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001635" ;
    a owl:Class ;
    rdfs:label "excess pharyngeal cells" ;
    rdfs:subClassOf obo:WBPhenotype_0000707, obo:WBPhenotype_0002175 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005460
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001636
    obo:IAO_0000115 "Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001636" ;
    a owl:Class ;
    rdfs:label "excess intestinal cells" ;
    rdfs:subClassOf obo:WBPhenotype_0000708, obo:WBPhenotype_0002175 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005792
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001637
    obo:IAO_0000115 "Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001637" ;
    a owl:Class ;
    rdfs:label "no Intestine" ;
    rdfs:subClassOf obo:WBPhenotype_0000708, obo:WBPhenotype_0002174 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005772
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001638
    obo:IAO_0000115 "OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes." ;
    obo:IAO_0100001 obo:WBPhenotype_0002561 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001638" ;
    a owl:Class ;
    rdfs:label "obsolete endosome fusion defective" ;
    owl:deprecated true .

obo:WBPhenotype_0001639
    obo:IAO_0000115 "Animals exhibit a decrease in their high-speed movement in the forward direction with brief backward movement compared to control. In C. elegans, Animals do not move more than a few body lengths from their starting position and searches occur locally with pivoting behavior." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lurcher", "path range decreased" ;
    oboInOwl:id "WBPhenotype:0001639" ;
    a owl:Class ;
    rdfs:label "roaming reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000238, obo:WBPhenotype_0001213, obo:WBPhenotype_0002315 .

obo:WBPhenotype_0001640
    obo:IAO_0000115 "Animals are unable to acidify compartments to the same level as that observed in control animals given the same stimulus." ;
    oboInOwl:hasNarrowSynonym "acidification level abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001640" ;
    a owl:Class ;
    rdfs:label "acidification level defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000607 .

obo:WBPhenotype_0001641
    obo:IAO_0000115 "Animals lack or exhibit defects in the posterior body muscle contractions during the defecation cycle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "pBoc" ;
    oboInOwl:id "WBPhenotype:0001641" ;
    a owl:Class ;
    rdfs:label "posterior body wall contraction defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000157 .

obo:WBPhenotype_0001642
    obo:IAO_0000115 "Variations that disrupt stereotypical embryonic cleavage patterns (such as cleavage rate, division axes or asymmetric division)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001642" ;
    a owl:Class ;
    rdfs:label "cell cleavage variant emb" ;
    rdfs:subClassOf obo:WBPhenotype_0000266 .

obo:WBPhenotype_0001643
    obo:IAO_0000115 "Embryos generate an excess number of hypodermal cells compared to control." ;
    oboInOwl:hasBroadSynonym "Skn" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001643" ;
    a owl:Class ;
    rdfs:label "excess hypodermal cells" ;
    rdfs:subClassOf obo:WBPhenotype_0002175, obo:WBPhenotype_0002569 .

obo:WBPhenotype_0001644
    obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of proteins in the organism compared to control." ;
    oboInOwl:hasNarrowSynonym "protein metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001644" ;
    a owl:Class ;
    rdfs:label "protein metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000463, obo:WBPhenotype_0000585 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0019538
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001645
    obo:IAO_0000115 "Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control." ;
    oboInOwl:hasNarrowSynonym "protein degradation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001645" ;
    a owl:Class ;
    rdfs:label "protein degradation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001644 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030163
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001646
    obo:IAO_0000115 "Embryos fail to generate cells that exhibit pharyngeal specification." ;
    oboInOwl:hasBroadSynonym "Pha" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001646" ;
    a owl:Class ;
    rdfs:label "no pharynx" ;
    rdfs:subClassOf obo:WBPhenotype_0000707 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003681
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001647
    obo:IAO_0000115 "Any variation in the progression of the posterior portion of the pharynx over time compared to control. In C. elegans the posterior region includes the isthmus and terminal bulb (second bulb)." ;
    oboInOwl:hasNarrowSynonym "posterior pharynx abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001647" ;
    a owl:Class ;
    rdfs:label "posterior pharynx variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000707 .

obo:WBPhenotype_0001648
    obo:IAO_0000115 "Embryos fail to generate cells that give rise to the posterior portion of the pharynx. In C. elegans, the MS blastomere- derived pharyngeal cells constitute the posterior portion of the pharynx." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001648" ;
    a owl:Class ;
    rdfs:label "no posterior pharynx" ;
    rdfs:subClassOf obo:WBPhenotype_0001646, obo:WBPhenotype_0001647 .

obo:WBPhenotype_0001649
    obo:IAO_0000115 "Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals." ;
    oboInOwl:hasExactSynonym "5 FU resistant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001649" ;
    a owl:Class ;
    rdfs:label "Fluorouracil resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_46345
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001650
    obo:IAO_0000115 "Germ cell death fails in response to the concentration of 5-FU that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, in addition to cell death, 5-FU exposed animals exhibit condensed germ cell nuclei or unhealthy nuclei." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001650" ;
    a owl:Class ;
    rdfs:label "germ cell death response to 5 FU resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001649 .

obo:WBPhenotype_0001651
    obo:IAO_0000115 "Animals grow well during or after exposure to 5-FU under conditions where control animals are growth inhibited." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001651" ;
    a owl:Class ;
    rdfs:label "growth arrest response to 5 FU resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001649 .

obo:WBPhenotype_0001652
    obo:IAO_0000115 "Any variation in the process by which the gonad anchor cell makes contact with vulval cells in order to create a uterine-vulval connection. In C. elegans, this includes the loss of the basement membranes between these cells and the crossing of the basolateral portion of the anchor cell through this gap." ;
    oboInOwl:hasNarrowSynonym "anchor cell invasion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001652" ;
    a owl:Class ;
    rdfs:label "anchor cell invasion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000283 .

obo:WBPhenotype_0001653
    obo:IAO_0000115 "Animals exhibit variations in their response to cadmium compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "cadmium response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001653" ;
    a owl:Class ;
    rdfs:label "cadmium response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_22977
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001654
    obo:IAO_0000115 "Animals fail to respond to the concentration of cadmium that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to cadmium to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001654" ;
    a owl:Class ;
    rdfs:label "cadmium resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001653 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_22977
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001655
    obo:IAO_0000115 "Animals respond to cadmium at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001655" ;
    a owl:Class ;
    rdfs:label "cadmium hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001653 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_22977
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001656
    obo:IAO_0000115 "Any variation in the progression of the leader cell that guides and shapes the outgrowth of the gonad while crawling along the body wall to force the germline to extend into a long tubular shape over time from its formation to its mature structure compared to control." ;
    oboInOwl:hasNarrowSynonym "distal tip cell development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001656" ;
    a owl:Class ;
    rdfs:label "distal tip cell development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000399 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0006865
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001657
    obo:IAO_0000115 "Animals exhibit variations in the specialized region of connection between two cells or between a cell and the extracellular matrix compared to control." ;
    oboInOwl:hasNarrowSynonym "cell junction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001657" ;
    a owl:Class ;
    rdfs:label "cell junction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001399 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030054
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001658
    obo:IAO_0000115 "Animals exhibit variations in the specialized region of connection between two cells compared to control." ;
    oboInOwl:hasNarrowSynonym "intercellular junction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "cell cell junction abnormal" ;
    oboInOwl:id "WBPhenotype:0001658" ;
    a owl:Class ;
    rdfs:label "intercellular junction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001657 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005911
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001659
    obo:IAO_0000115 "Any variation in the form, structure or composition of the somatic gonad structure that connects the distal gonad arm to the uterus compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "spermatheca morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001659" ;
    a owl:Class ;
    rdfs:label "spermatheca morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000977 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005319
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001660
    obo:IAO_0000115 "The two morphologically bilaterally symmetric gustatory neurons ASE left (ASEL) and ASE right (ASER) fail to undergo a left/right asymmetric diversification in cell fate." ;
    oboInOwl:hasNarrowSynonym "2ASEL", "2ASER" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001660" ;
    a owl:Class ;
    rdfs:label "loss of asymmetry ASE" ;
    rdfs:subClassOf obo:WBPhenotype_0001510, obo:WBPhenotype_0001512 .

obo:WBPhenotype_0001661
    obo:IAO_0000115 "The two morphologically bilaterally symmetric olfactory neurons AWC left (AWCL) and AWC right (AWCR) fail to undergo a left/right asymmetric diversification in cell fate." ;
    oboInOwl:hasNarrowSynonym "2 AWC off", "2 AWC on" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001661" ;
    a owl:Class ;
    rdfs:label "loss of asymmetry AWC" ;
    rdfs:subClassOf obo:WBPhenotype_0001510, obo:WBPhenotype_0001512 .

obo:WBPhenotype_0001662
    obo:IAO_0000115 "Any variation in the progression of the somatic gonad structure that connects the distal gonad arm to the uterus over time from an initial condition to a later condition compared to control animals." ;
    oboInOwl:hasNarrowSynonym "spermatheca development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001662" ;
    a owl:Class ;
    rdfs:label "spermatheca development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000399 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0005319
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001663
    obo:IAO_0000115 "Animals fail to respond to the levels of reactive oxygen species that elicit a response in control animals." ;
    oboInOwl:hasBroadSynonym "Oxr" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001663" ;
    a owl:Class ;
    rdfs:label "organism oxidative stress resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001620 .

obo:WBPhenotype_0001664
    obo:IAO_0000115 "The frequency of sex chromosome segregation is perturbed, resulting in the production of exceptional gametes (e.g. ova or sperm) and populations with a sex ratio altered from the rate of 1:500 as observed for control populations." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001664" ;
    a owl:Class ;
    rdfs:label "X chromosome nondisjunction" ;
    rdfs:subClassOf obo:WBPhenotype_0001174 .

obo:WBPhenotype_0001665
    obo:IAO_0000115 "Lower numbers of male progeny occur in the population compared to control populations. In C. elegans, the low incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an decrease in X chromosome nondisjunction." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001665" ;
    a owl:Class ;
    rdfs:label "low incidence male progeny" ;
    rdfs:subClassOf obo:WBPhenotype_0001664 .

obo:WBPhenotype_0001666
    obo:IAO_0000115 "Animals respond to iononizing radiation at a lower dose or a shorter exposure compared to control animals. Iononizing radiation has a wavelength in the 10 to 0.01 nanometer range. In C. elegans, increased sensitivity to X-ray irradiation is often observed as a decrease in survival upon exposure compared to control animals given the same treatment." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001666" ;
    a owl:Class ;
    rdfs:label "organism hypersensitive X ray irradiation" ;
    rdfs:subClassOf obo:WBPhenotype_0000276, obo:WBPhenotype_0000711 .

obo:WBPhenotype_0001667
    obo:IAO_0000115 "Animals respond to the chemical mutagen methyl methanesulfonate (MMS) a methanesulfonate ester and alkylating agent at a lower concentration or a shorter exposure compared to control animals. In C. elegans, increased sensitivity to MMS can be observed as a decrease in egg hatch upon acute exposure or inhibition of growth after chronic exposure compared to control animals given the same treatment." ;
    oboInOwl:hasExactSynonym "MMS hypersensitive" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001667" ;
    a owl:Class ;
    rdfs:label "methyl methanesulfonate hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000498 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_25255
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001668
    obo:IAO_0000115 "An increased number of oocytes are retained in the gonad without becoming endomitotic, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "oocyte number increased" ;
    oboInOwl:id "WBPhenotype:0001668" ;
    a owl:Class ;
    rdfs:label "oocyte accumulation" ;
    rdfs:subClassOf obo:WBPhenotype_0001260 .

obo:WBPhenotype_0001669
    obo:IAO_0000115 "Animals exhibit a variation in the ratio of synaptic vesicles per synapse of a neuron, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "presynaptic vesicle number abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "synaptic vesicle number abnormal" ;
    oboInOwl:id "WBPhenotype:0001669" ;
    a owl:Class ;
    rdfs:label "presynaptic vesicle number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001321 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008021
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001670
    obo:IAO_0000115 "Animals exhibit an overall decrease in the quantity of synaptic vesicles at the synapse compared to control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001322" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "synaptic vesicle number reduced" ;
    oboInOwl:id "WBPhenotype:0001670" ;
    a owl:Class ;
    rdfs:label "presynaptic vesicle number reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001669 .

obo:WBPhenotype_0001671
    obo:IAO_0000115 "Animals display variations in the distribution of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "vesicle organization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001671" ;
    a owl:Class ;
    rdfs:label "vesicle organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016050
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001672
    obo:IAO_0000115 "Animals exhibit variations in the extension of the part of the axon that forms a bridge between body regions, compared to control animals." ;
    oboInOwl:hasNarrowSynonym "commisure growth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001672" ;
    a owl:Class ;
    rdfs:label "commisure growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001224 .

obo:WBPhenotype_0001673
    obo:IAO_0000115 "Animals exhibit variations in the processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA, which allow the chromosome to persist from generation to generation, compared to control." ;
    oboInOwl:hasNarrowSynonym "telomere homeostasis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001673" ;
    a owl:Class ;
    rdfs:label "telomere homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000585 .

obo:WBPhenotype_0001674
    obo:IAO_0000115 "Animals exhibit variations in the sequence or organization of the components of the terminal region of its chromosome, (i.e. telomere, which serves to stabilize the chromosome) compared to control." ;
    oboInOwl:hasNarrowSynonym "telomere morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001674" ;
    a owl:Class ;
    rdfs:label "telomere morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001348 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000781
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001675
    obo:IAO_0000115 "Males exhibit variations in the reproductive system, from its formation to the mature structure compared to control." ;
    oboInOwl:hasNarrowSynonym "male gonad development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001675" ;
    a owl:Class ;
    rdfs:label "male gonad development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000691 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0006794
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001676
    obo:IAO_0000115 "Animals exhibit variations in the structure or composition of any neuron within the class of sensory neurons responsible for relaying mechanical stimuli to the animal compared to control." ;
    oboInOwl:hasNarrowSynonym "touch receptor cell morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "mechanosensory neuron abnormal", "microtubule cell morphology abnormal" ;
    oboInOwl:id "WBPhenotype:0001676" ;
    a owl:Class ;
    rdfs:label "touch receptor cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000905 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005237
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001677
    obo:IAO_0000115 "Animals display cuticle components displayed by animals of a different developmental stage, compared to control." ;
    oboInOwl:hasNarrowSynonym "Srf", "stage specific cuticle antigenicity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001677" ;
    a owl:Class ;
    rdfs:label "stage specific cuticle antigenicity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001687 .

obo:WBPhenotype_0001678
    obo:IAO_0000115 "Animals produce cuticles that vary in components such as proteins or carbohydrates, observed in control animals of the same developmental stage and raised under the same conditions." ;
    oboInOwl:hasNarrowSynonym "cuticle physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001678" ;
    a owl:Class ;
    rdfs:label "cuticle physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001210 .

obo:WBPhenotype_0001679
    obo:IAO_0000115 "Neurons have more than one process extending from the cell body." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001679" ;
    a owl:Class ;
    rdfs:label "multipolar neuron" ;
    rdfs:subClassOf obo:WBPhenotype_0000905 .

obo:WBPhenotype_0001680
    obo:IAO_0000115 "Vulval precursor cells forgo further cell division and fuse to the hypodermis instead of adopting their intended fate (becoming primary, secondary or tertiary vulval cells)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "F fate abnormal", "VPC fused fate abnormal" ;
    oboInOwl:id "WBPhenotype:0001680" ;
    a owl:Class ;
    rdfs:label "adoption of fused vulval cell fate" ;
    rdfs:subClassOf obo:WBPhenotype_0001272 .

obo:WBPhenotype_0001681
    obo:IAO_0000115 "The alignment of the spindle relative to other cellular structures varies from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "spindle orientation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001681" ;
    a owl:Class ;
    rdfs:label "spindle orientation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001344, obo:WBPhenotype_0002414 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000133
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005819
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001682
    obo:IAO_0000115 "Organisms respond to UV at a higer dose or a longer exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001682" ;
    a owl:Class ;
    rdfs:label "organism UV resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000143 .

obo:WBPhenotype_0001683
    obo:IAO_0000115 "Variations that specifically disrupt sperm production in XX hermaphrodites. By contrast, spermatogenesis in XO males remains unaffected." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001683" ;
    a owl:Class ;
    rdfs:label "spermatogenesis defective hermaphrodite" ;
    rdfs:subClassOf obo:WBPhenotype_0000670 .

obo:WBPhenotype_0001684
    obo:IAO_0000115 "The rates of synaptic vesicle exocytosis and endocytosis vary from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "synaptic vesicle homeostasis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001684" ;
    a owl:Class ;
    rdfs:label "synaptic vesicle homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000846 .

obo:WBPhenotype_0001685
    obo:IAO_0000115 "The region opposite to the presynaptic region deviates in the structure, configuration or ratio of its components specific for receiving signals from the other side of the synapse compared to control." ;
    oboInOwl:hasNarrowSynonym "postsynaptic region morphology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001685" ;
    a owl:Class ;
    rdfs:label "postsynaptic region morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000616 .

obo:WBPhenotype_0001686
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process in the region, opposite to the presynaptic region, which is required for receiving signals from the other side of the synapse compared to control." ;
    oboInOwl:hasNarrowSynonym "postsynaptic region physiology abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001686" ;
    a owl:Class ;
    rdfs:label "postsynaptic region physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000584 .

obo:WBPhenotype_0001687
    obo:IAO_0000115 "Cuticles of animals or cuticular extracts exhibit an altered pattern of antibody binding compared to Bristol N2 animals of the same developmental stage." ;
    oboInOwl:hasBroadSynonym "Srf" ;
    oboInOwl:hasNarrowSynonym "surface antigenicity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001687" ;
    a owl:Class ;
    rdfs:label "surface antigenicity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001688 .

obo:WBPhenotype_0001688
    obo:IAO_0000115 "The electron dense, amorphous envelope that comprises the outermost layer of the cuticle varies in composition from that observed in control animals of the same developmental stage. The integrity of the surface coat is often revealed by an altered antigenicity or biochemical make up." ;
    oboInOwl:hasBroadSynonym "Srf" ;
    oboInOwl:hasNarrowSynonym "surface coat abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001688" ;
    a owl:Class ;
    rdfs:label "surface coat variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000201, obo:WBPhenotype_0001678 .

obo:WBPhenotype_0001689
    obo:IAO_0000115 "Cuticles or cuticular extracts do not bind antibodies that are observed to bind the surfaces or cuticular extracts of Bristol N2 animals of the same developmental stage." ;
    oboInOwl:hasNarrowSynonym "Srf" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001689" ;
    a owl:Class ;
    rdfs:label "surface antigen negative" ;
    rdfs:subClassOf obo:WBPhenotype_0001687 .

obo:WBPhenotype_0001690
    obo:IAO_0000115 "Animals display surface antigens throughout all larval stages, unlike Bristol N2 worms, which display the antigens only during one larval stage." ;
    oboInOwl:hasBroadSynonym "Cld" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001690" ;
    a owl:Class ;
    rdfs:label "constitutive larval display" ;
    rdfs:subClassOf obo:WBPhenotype_0001677 .

obo:WBPhenotype_0001691
    obo:IAO_0000115 "Germ nuclei are misplaced in the gonad and are observed in the rachis. Sheath cells are observed protruding between these nuclei. Meiotic or mitotic specification of germ nuclei is not affected." ;
    oboInOwl:hasNarrowSynonym "germ line morphogenesis(Glm)" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001691" ;
    a owl:Class ;
    rdfs:label "germ nuclei rachis" ;
    rdfs:subClassOf obo:WBPhenotype_0001940 .

obo:WBPhenotype_0001692
    obo:IAO_0000115 "Animals are not induced to display surface antigens by exposure to pheromone as observed for Bristol N2 animals." ;
    oboInOwl:hasExactSynonym "ILD abnormal" ;
    oboInOwl:hasNarrowSynonym "pheromone induced larval display abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "induced larval display abnormal" ;
    oboInOwl:id "WBPhenotype:0001692" ;
    a owl:Class ;
    rdfs:label "pheromone induced larval display defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001687 .

obo:WBPhenotype_0001693
    obo:IAO_0000115 "Males have alae that extend into the tail region. Alae are small linear ridges running along the lateral lines of the cuticle. In C. elegans alae do not extend into the tail region (Wormatlas)." ;
    oboInOwl:hasBroadSynonym "Pal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001693" ;
    a owl:Class ;
    rdfs:label "male posterior alae" ;
    rdfs:subClassOf obo:WBPhenotype_0000202, obo:WBPhenotype_0001240 .

obo:WBPhenotype_0001694
    obo:IAO_0000115 "Hermaphrodites continue to produce sperm past the time at which the transition to oogenesis normally occurs. Thus, germ cells that would normally become oocytes are transformed into sperm instead." ;
    oboInOwl:hasNarrowSynonym "spermatogenesis to oogenesis switch abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001694" ;
    a owl:Class ;
    rdfs:label "spermatogenesis to oogenesis switch defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001572 .

obo:WBPhenotype_0001695
    obo:IAO_0000115 "Animals exhibit variations in their catalytic ability the transfer glycolsyl groups from one compound (donor) to another (acceptor) often measured by a reduction in the amount of glycosylated products compared to that observed in control animals of the same developmental stage." ;
    oboInOwl:hasNarrowSynonym "glycosyltransferase activity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001695" ;
    a owl:Class ;
    rdfs:label "glycosyltransferase activity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000733 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016757
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001696
    obo:IAO_0000115 "Animals exhibit variations in the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones compared to control." ;
    oboInOwl:hasNarrowSynonym "biosynthesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001696" ;
    a owl:Class ;
    rdfs:label "biosynthesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000463 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009058
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001697
    obo:IAO_0000115 "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of chondroitin sulfate compared to control." ;
    oboInOwl:hasNarrowSynonym "chondroitin biosynthesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001697" ;
    a owl:Class ;
    rdfs:label "chondroitin biosynthesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001696 .

obo:WBPhenotype_0001698
    obo:IAO_0000115 "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan compared to control." ;
    oboInOwl:hasNarrowSynonym "heparan sulfate biosynthesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001698" ;
    a owl:Class ;
    rdfs:label "heparan sulfate biosynthesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001696 .

obo:WBPhenotype_0001699
    obo:IAO_0000115 "Specific body regions of an animal display variations in movement compared to that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "localized movement abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001699" ;
    a owl:Class ;
    rdfs:label "localized movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001206 .

obo:WBPhenotype_0001700
    obo:IAO_0000115 "Animals exhibit variations in movement in liquid from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "swimming abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "movement in liquid abnormal", "thrashing abnormal" ;
    oboInOwl:id "WBPhenotype:0001700" ;
    a owl:Class ;
    rdfs:label "swimming variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001206 .

obo:WBPhenotype_0001701
    obo:IAO_0000115 "Animals exhibit uncharacteristic muscle contractions during the process by which they travel from one location to another." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "convulsive" ;
    oboInOwl:id "WBPhenotype:0001701" ;
    a owl:Class ;
    rdfs:label "spastic locomotion" ;
    rdfs:subClassOf obo:WBPhenotype_0004017 .

obo:WBPhenotype_0001702
    obo:IAO_0000115 "Animals exhibit variations in the directional changes that separate consecutive runs, from that observed for control animals. In C. elegans, these aberrations include variations in the form or extent of omega turns or reversals (shifts from forward to backward movements)." ;
    oboInOwl:hasNarrowSynonym "directionality abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "reversal abnormal", "turning abnormal" ;
    oboInOwl:id "WBPhenotype:0001702" ;
    a owl:Class ;
    rdfs:label "directionality variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004017 .

obo:WBPhenotype_0001703
    obo:IAO_0000115 "Any variation in the maximum ventral and dorsal flex of the animal compared to control animals." ;
    oboInOwl:hasNarrowSynonym "body bend abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001703" ;
    a owl:Class ;
    rdfs:label "body bend variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004018 .

obo:WBPhenotype_0001704
    obo:IAO_0000115 "Alae contain more cuticular ridges than control animals. In C. elegans alae are composed of three cuticular ridges." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001704" ;
    a owl:Class ;
    rdfs:label "multiple alae" ;
    rdfs:subClassOf obo:WBPhenotype_0001412 .

obo:WBPhenotype_0001705
    obo:IAO_0000115 "The directed movement of molecules between the nucleus and the cytoplasm is impaired." ;
    oboInOwl:hasNarrowSynonym "nucleocytoplasmic transport abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001705" ;
    a owl:Class ;
    rdfs:label "nucleocytoplasmic transport defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001283 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:GO_0006913
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001706
    obo:IAO_0000115 "The directed movement of substances out of the nucleus is impaired." ;
    oboInOwl:hasNarrowSynonym "nuclear export abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001706" ;
    a owl:Class ;
    rdfs:label "nuclear export defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001705 .

obo:WBPhenotype_0001707
    obo:IAO_0000115 "The directed movement of substances into the nucleus is impaired." ;
    oboInOwl:hasNarrowSynonym "nuclear import abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001707" ;
    a owl:Class ;
    rdfs:label "nuclear import defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001705 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:GO_0051170
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001708
    obo:IAO_0000115 "The directed movement of a protein from the nucleus into the cytoplasm is impaired." ;
    oboInOwl:hasNarrowSynonym "protein export from nucleus abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001708" ;
    a owl:Class ;
    rdfs:label "protein export from nucleus defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001706 .

obo:WBPhenotype_0001709
    obo:IAO_0000115 "Animals exhibit variations in light/dark cycle recurrence of reactions to stress conditions compared to that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "rhythmic tolerance to stress abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "circadian variation in stress tolerance abnormal" ;
    oboInOwl:id "WBPhenotype:0001709" ;
    a owl:Class ;
    rdfs:label "rhythmic tolerance to stress variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067, obo:WBPhenotype_0001711 .

obo:WBPhenotype_0001710
    obo:IAO_0000115 "Animals exhibit variations in light/dark cycle recurrence of reactions to osmotic stress compared to that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "rhythmic tolerance to osmotic stress abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001710" ;
    a owl:Class ;
    rdfs:label "rhythmic tolerance to osmotic stress variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001709 .

obo:WBPhenotype_0001711
    obo:IAO_0000115 "Animals exhibit variations in actions or responses that occur with measurable periodicity, from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "rhythmic behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001711" ;
    a owl:Class ;
    rdfs:label "rhythmic behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007622
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001712
    obo:IAO_0000115 "Animals exhibit variations in the actions or reactions that recur with a periodicity associated with light/dark cycles, compared to control." ;
    oboInOwl:hasNarrowSynonym "circadian rhythm behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001712" ;
    a owl:Class ;
    rdfs:label "circadian rhythm behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001711 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048512
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001713
    obo:IAO_0000115 "Animals exhibit variations in locomotor activity during its light/dark cycle from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "locomotory rhythm abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001713" ;
    a owl:Class ;
    rdfs:label "locomotory rhythm variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001711 .

obo:WBPhenotype_0001714
    obo:IAO_0000115 "Animals exhibit variations in turning bouts, consisting of one or more sharp turning events separating consecutive runs, which serve to orient the animal within a gradient, compared to control." ;
    oboInOwl:hasNarrowSynonym "pirouette abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001714" ;
    a owl:Class ;
    rdfs:label "pirouette variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002311 .

obo:WBPhenotype_0001715
    obo:IAO_0000115 "Animals exhibit variations in the number of directional changes over time from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "frequency of directionality abnormal", "pirouette frequency abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001715" ;
    a owl:Class ;
    rdfs:label "pirouette frequency variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001714 .

obo:WBPhenotype_0001716
    obo:IAO_0000115 "Animals exhibit variations in the velocity of forward translocation of any point along the animal's track from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "forward point velocity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001716" ;
    a owl:Class ;
    rdfs:label "forward point velocity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004025 .

obo:WBPhenotype_0001717
    obo:IAO_0000115 "Animals exhibit variations in the translocation of the mean position of the rear two-thirds (centroid position) of the animal over time, from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "centroid velocity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001717" ;
    a owl:Class ;
    rdfs:label "centroid velocity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004025 .

obo:WBPhenotype_0001718
    obo:IAO_0000115 "Animals exhibit variations in the mean translocation of the points along the animal's track compared to control." ;
    oboInOwl:hasNarrowSynonym "instantaneous velocity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001718" ;
    a owl:Class ;
    rdfs:label "instantaneous velocity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004025 .

obo:WBPhenotype_0001719
    obo:IAO_0000115 "Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones." ;
    oboInOwl:hasNarrowSynonym "unfolded protein response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ER unfolded protein response abnormal", "UPR", "unfolded protein response" ;
    oboInOwl:id "WBPhenotype:0001719" ;
    a owl:Class ;
    rdfs:label "unfolded protein response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0001644 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006986
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001720
    obo:IAO_0000115 "Spermatozoa do not crawl back into the spermatheca after being swept into the uterus by passing oocytes." ;
    oboInOwl:hasNarrowSynonym "spermatozoa retro location abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "spermatheca homing abnormal" ;
    oboInOwl:id "WBPhenotype:0001720" ;
    a owl:Class ;
    rdfs:label "spermatozoa retro location defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000389, obo:WBPhenotype_0001386 .

obo:WBPhenotype_0001721
    obo:IAO_0000115 "Animals exhibit variations in the extent of pathogen invasion into the pharynx compared to control. This is often measured as the percentage of animals exhibiting a pathogen-invaded pharynx within a given population." ;
    oboInOwl:hasNarrowSynonym "pathogen infected pharynx abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001721" ;
    a owl:Class ;
    rdfs:label "pathogen infected pharynx variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001012 .

obo:WBPhenotype_0001722
    obo:IAO_0000115 "Animals exhibit a greater extent of pathogen invasion into the pharynx compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001722" ;
    a owl:Class ;
    rdfs:label "pathogen infected pharynx increase" ;
    rdfs:subClassOf obo:WBPhenotype_0001721 .

obo:WBPhenotype_0001723
    obo:IAO_0000115 "Animals exhibit a lesser extent of pathogen invasion into the pharynx compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001723" ;
    a owl:Class ;
    rdfs:label "pathogen infected pharynx decrease" ;
    rdfs:subClassOf obo:WBPhenotype_0001721 .

obo:WBPhenotype_0001724
    obo:IAO_0000115 "Animals respond to tunicamycin at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001724" ;
    a owl:Class ;
    rdfs:label "tunicamycin hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000359 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_29699
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001725
    obo:IAO_0000115 "Cells exhibit variations in the response to osmotic stress compared to control. In C. elegans, exposure to stress-inducing osmotic conditions invokes cellular changes, including transcriptional up or down-regulation of genes." ;
    oboInOwl:hasNarrowSynonym "osmotic stress response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001725" ;
    a owl:Class ;
    rdfs:label "cellular osmotic stress response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0071470
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001726
    obo:IAO_0000115 "Animals vary in the distance between anterior and posterior ends of the animal from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "body length abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001726" ;
    a owl:Class ;
    rdfs:label "body length variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000231 .

obo:WBPhenotype_0001727
    obo:IAO_0000115 "Animals vary in the distance between dorsal and ventral sides when measured across the body at right angles to the length, from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "body width abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001727" ;
    a owl:Class ;
    rdfs:label "body width variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000231 .

obo:WBPhenotype_0001728
    obo:IAO_0000115 "Males differ from control animals in their ability to form copulatory plugs or their placement of these plugs. In C. elegans, males of the Hawaiian strain (CB4856) typically form mating plugs." ;
    oboInOwl:hasNarrowSynonym "mating plug production abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001728" ;
    a owl:Class ;
    rdfs:label "mating plug production variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000928 .

obo:WBPhenotype_0001729
    obo:IAO_0000115 "Males form copulatory mating plugs." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "mating plug plus", "plug plus" ;
    oboInOwl:id "WBPhenotype:0001729" ;
    a owl:Class ;
    rdfs:label "mating plug produced" ;
    rdfs:subClassOf obo:WBPhenotype_0001728 .

obo:WBPhenotype_0001730
    obo:IAO_0000115 "Males do not form copulatory mating plug." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "mating plug minus", "plug minus" ;
    oboInOwl:id "WBPhenotype:0001730" ;
    a owl:Class ;
    rdfs:label "mating plug deficient" ;
    rdfs:subClassOf obo:WBPhenotype_0001728 .

obo:WBPhenotype_0001731
    obo:IAO_0000115 "Animals exhibit variations in the duration of the trajectory of the forward track in a thermal gradient compared to control." ;
    oboInOwl:hasNarrowSynonym "thermal bias in tracking abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "cryophilic bias" ;
    oboInOwl:id "WBPhenotype:0001731" ;
    a owl:Class ;
    rdfs:label "thermal bias in tracking variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000478 .

obo:WBPhenotype_0001732
    obo:IAO_0000115 "Animals exhibit variations in their response and ability to survive over a range of pH conditions compared to control." ;
    oboInOwl:hasNarrowSynonym "organism response to pH abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001732" ;
    a owl:Class ;
    rdfs:label "organism response to pH variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009268
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001733
    obo:IAO_0000115 "Animals treated with pheromone do not exhibit a decrease in pumping rate similar to that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "pheromone suppressed pumping abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001733" ;
    a owl:Class ;
    rdfs:label "pheromone suppressed pumping defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001287 .

obo:WBPhenotype_0001734
    obo:IAO_0000115 "Animals deprived of food do not exhibit a decrease in pumping rate similar to that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "starvation suppressed pumping abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "food deprived suppression of pumping abnormal" ;
    oboInOwl:id "WBPhenotype:0001734" ;
    a owl:Class ;
    rdfs:label "starvation suppressed pumping defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001287 .

obo:WBPhenotype_0001735
    obo:IAO_0000115 "Animals exhibit variations in the frequency, rate or extent of muscle contraction compared to control animals." ;
    oboInOwl:hasNarrowSynonym "muscle cell activity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001735" ;
    a owl:Class ;
    rdfs:label "muscle cell activity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000990 .

obo:WBPhenotype_0001736
    obo:IAO_0000115 "Failure to execute the characteristic response to acetate compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001736" ;
    a owl:Class ;
    rdfs:label "acetate chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000015 .

obo:WBPhenotype_0001737
    obo:IAO_0000115 "Animals are unable to locate the gradient peak of a water soluble compound, which was generated on a uniform concentration of another compound." ;
    oboInOwl:hasNarrowSynonym "aqueous compound discrimination abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001737" ;
    a owl:Class ;
    rdfs:label "aqueous compound discrimination defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001443 .

obo:WBPhenotype_0001738
    obo:IAO_0000115 "Failure to execute the characteristic response to ammonium compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001738" ;
    a owl:Class ;
    rdfs:label "ammonium chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000015 .

obo:WBPhenotype_0001739
    obo:IAO_0000115 "Any variation in an organism's decline over time from its optimal fertility and viability compared to control animals." ;
    oboInOwl:hasNarrowSynonym "aging abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001739" ;
    a owl:Class ;
    rdfs:label "aging variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000576 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007568
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001740
    obo:IAO_0000115 "Any variation in the preprogrammed process that occurs in an organism that is associated with the dismantling of an organ and an overall decline in metabolic function compared to control animals. This may include variations in the rate or extent of morphological disarray and of the breakdown or organelles, membranes and other cellular components." ;
    oboInOwl:hasNarrowSynonym "organ senescence abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001740" ;
    a owl:Class ;
    rdfs:label "organ senescence variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530, obo:WBPhenotype_0000534, obo:WBPhenotype_0000575, obo:WBPhenotype_0001739 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010260
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001741
    obo:IAO_0000115 "Males exhibit spicule-muscle seizures leading to inappropriately timed protraction compared to control." ;
    oboInOwl:hasBroadSynonym "Prc" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "precocious spicule protraction", "protraction constitutive" ;
    oboInOwl:id "WBPhenotype:0001741" ;
    a owl:Class ;
    rdfs:label "spontaneous spicule protraction" ;
    rdfs:subClassOf obo:WBPhenotype_0002443 .

obo:WBPhenotype_0001742
    obo:IAO_0000115 "The endogenous anabolism of any lipid species has been increased compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001742" ;
    a owl:Class ;
    rdfs:label "lipid synthesis increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000725 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008610
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001743
    obo:IAO_0000115 "Any variation in the division of the eukaryotic cell nucleus to produce two daughter nuclei that contain the identical chromosome complement of their mother compared to control." ;
    oboInOwl:hasNarrowSynonym "mitosis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001743" ;
    a owl:Class ;
    rdfs:label "mitosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1903047
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001744
    obo:IAO_0000115 "Any variation in the attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix compared to control." ;
    oboInOwl:hasNarrowSynonym "cell adhesion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001744" ;
    a owl:Class ;
    rdfs:label "cell adhesion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001657 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007155
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001745
    obo:IAO_0000115 "Any variation in a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control." ;
    oboInOwl:hasNarrowSynonym "adherens junction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001745" ;
    a owl:Class ;
    rdfs:label "adherens junction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001658 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:GO_0005912
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001746
    obo:IAO_0000115 "Any perturbation in the belt-like region of very close contact between the plasma membranes of adjacent cells that results in the complete occlusion of the intercellular space." ;
    oboInOwl:hasExactSynonym "zonula occludens abnormal" ;
    oboInOwl:hasNarrowSynonym "tight junction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001746" ;
    a owl:Class ;
    rdfs:label "tight junction defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001658 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0070160
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001747
    obo:IAO_0000115 "Animals exhibit variations in the change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus compared to control." ;
    oboInOwl:hasNarrowSynonym "zinc response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001747" ;
    a owl:Class ;
    rdfs:label "zinc response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000077
                [
                    a owl:Restriction ;
                    owl:onProperty obo:BFO_0000070 ;
                    owl:someValuesFrom obo:CHEBI_30185
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001748
    obo:IAO_0000115 "The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity." ;
    oboInOwl:hasExactSynonym "Pun" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001748" ;
    a owl:Class ;
    rdfs:label "pharynx unattached" ;
    rdfs:subClassOf obo:WBPhenotype_0000707 .

obo:WBPhenotype_0001749
    obo:IAO_0000115 "The toxic response to zinc occurs at a lower concentration or a shorter exposure compared to control animals. In C. elegans hypersensitive animals exhibit delayed development or lethality at concentrations of zinc (e.g. ZnSO4), which has little or no effect on control worms." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001749" ;
    a owl:Class ;
    rdfs:label "zinc toxicity hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001747 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_27363
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001750
    obo:IAO_0000115 "Animals fail to exhibit toxicity to the concentration of zinc that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to zinc include delayed development or lethality." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001750" ;
    a owl:Class ;
    rdfs:label "zinc toxicity resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001747 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_27363
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001751
    obo:IAO_0000115 "Animals exhibit increased lethality as a result of exposure to environments with a higher solute concentration than their own internal environment, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Hos", "hypertonic sensitive" ;
    oboInOwl:id "WBPhenotype:0001751" ;
    a owl:Class ;
    rdfs:label "organism hypertonic lethality increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000141, obo:WBPhenotype_0000876 .

obo:WBPhenotype_0001752
    obo:IAO_0000115 "Animals exhibit variations in vesicle-based directed movement of substances into, out of, or within a cell compared to control." ;
    oboInOwl:hasNarrowSynonym "vesicle trafficking abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001752" ;
    a owl:Class ;
    rdfs:label "vesicle trafficking variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016192
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001753
    obo:IAO_0000115 "Animals exhibit intensified accumulation of fluids or fluorescent markers etc. within their coelomocytes compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001753" ;
    a owl:Class ;
    rdfs:label "coelomocyte uptake increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001423 .

obo:WBPhenotype_0001754
    obo:IAO_0000115 "Contents of endosomes fail to be transported to lysosomal compartments." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001754" ;
    a owl:Class ;
    rdfs:label "endosome to lysosome trafficking defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001421 .

obo:WBPhenotype_0001755
    obo:IAO_0000115 "Animals do not arrest mitotic germ cell division, as control animals, when treated with UV radiation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001755" ;
    a owl:Class ;
    rdfs:label "UV induced mitotic germ cell arrest defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000100 .

obo:WBPhenotype_0001756
    obo:IAO_0000115 "Programmed cell death caused by UV radiation is reduced compared to control animals. In C. elegans, this is often measured in the pachytene region of the gonad." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001756" ;
    a owl:Class ;
    rdfs:label "UV induced apoptosis decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000100 .

obo:WBPhenotype_0001757
    obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of signalling peptides in the organism compared to control." ;
    oboInOwl:hasNarrowSynonym "neuropeptide metabolism abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001757" ;
    a owl:Class ;
    rdfs:label "neuropeptide metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0001758
    obo:IAO_0000115 "Variations in the chemical reactions and pathways involved in the formation and maturation of specialized peptidergic neurotransmitters encoded as preproproteins that are posttranslationally processed to yield bioactive neuropeptides compared to control (Wormatlas)." ;
    oboInOwl:hasNarrowSynonym "neuropeptide processing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001758" ;
    a owl:Class ;
    rdfs:label "neuropeptide processing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000122, obo:WBPhenotype_0001757 .

obo:WBPhenotype_0001759
    obo:IAO_0000115 "Variations in the biogenesis or stability of the 21U-RNA class of molecules compared to control. Molecules are classified as 21U-RNA based on the presence of a 5'U and a conserved upstream motif, which may specify the production of these molecules, in addition these molecules are typically 21nt in length." ;
    oboInOwl:hasNarrowSynonym "21U RNA expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "piRNA expression abnormal" ;
    oboInOwl:id "WBPhenotype:0001759" ;
    a owl:Class ;
    rdfs:label "21U RNA expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0001760
    obo:IAO_0000115 "Animals exhibit an increase in the rate of deletion events in mono-G or G-rich tracts within the genome compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001760" ;
    a owl:Class ;
    rdfs:label "G tract instability" ;
    rdfs:subClassOf obo:WBPhenotype_0000000 .

obo:WBPhenotype_0001761
    obo:IAO_0000115 "Regulated ventral midline crossing by axons vary either in the frequency of crossing events or the maintenance through development of process positions compared to control." ;
    oboInOwl:hasNarrowSynonym "axon midline crossing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001761" ;
    a owl:Class ;
    rdfs:label "axon midline crossing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000384 .

obo:WBPhenotype_0001762
    obo:IAO_0000115 "Yolk is not taken up by oocytes in the same manner or to the same degree as observed for control animals. This often leads to an accumulation of yolk in the pseudocoelom." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001762" ;
    a owl:Class ;
    rdfs:label "uptake of yolk defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001422, obo:WBPhenotype_0001424 .

obo:WBPhenotype_0001763
    obo:IAO_0000115 "Uptake of subtances from the intestine is altered from that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001763" ;
    a owl:Class ;
    rdfs:label "uptake by intestinal cell defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000986 .

obo:WBPhenotype_0001764
    obo:IAO_0000115 "Animals exhibit variations in their response to carbon dioxide compared to control." ;
    oboInOwl:hasNarrowSynonym "carbon dioxide response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001764" ;
    a owl:Class ;
    rdfs:label "carbon dioxide response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010037
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001765
    obo:IAO_0000115 "Variations in the characteristic movement away from specific CO2 levels compared to control. C. elegans avoids high levels of CO2." ;
    oboInOwl:hasNarrowSynonym "carbon dioxide avoidance abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "CO2 avoidance abnormal", "Cdad" ;
    oboInOwl:id "WBPhenotype:0001765" ;
    a owl:Class ;
    rdfs:label "carbon dioxide avoidance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001764 .

obo:WBPhenotype_0001766
    obo:IAO_0000115 "Animals are more sensitive to the reduction of cholesterol in the environment compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001766" ;
    a owl:Class ;
    rdfs:label "cholesterol depletion hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000725, obo:WBPhenotype_0002525 .

obo:WBPhenotype_0001767
    obo:IAO_0000115 "Outgrowth of the commissure occurs on the side of the body different from that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001767" ;
    a owl:Class ;
    rdfs:label "commissure handedness defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000181, obo:WBPhenotype_0000384 .

obo:WBPhenotype_0001768
    obo:IAO_0000115 "Variations in the quantity of circumferential axonal tracts from the number observed in control animals." ;
    oboInOwl:hasNarrowSynonym "commissure number abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001768" ;
    a owl:Class ;
    rdfs:label "commissure number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001226 .

obo:WBPhenotype_0001769
    obo:IAO_0000115 "Animals fail to silence cytoplasmic-localized RNAs. Nuclear-localized RNAs may still be sensitive to RNAi." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001769" ;
    a owl:Class ;
    rdfs:label "cytoplasmic RNAi defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 .

obo:WBPhenotype_0001770
    obo:IAO_0000115 "Animals exhibit variations in their selective interactions with small interfering RNA molecules compared to control." ;
    oboInOwl:hasNarrowSynonym "endo siRNA binding abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001770" ;
    a owl:Class ;
    rdfs:label "endo siRNA binding variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 .

obo:WBPhenotype_0001771
    obo:IAO_0000115 "Animals exhibit variations in the length or amount of any endogenous small interfering RNA molecule populations compared to control." ;
    oboInOwl:hasNarrowSynonym "endo siRNA production abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001771" ;
    a owl:Class ;
    rdfs:label "endo siRNA production variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 .

obo:WBPhenotype_0001772
    obo:IAO_0000115 "Animals exhibit an increase in the levels of transposase mRNA, from endogenous transposons, over that measured in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001772" ;
    a owl:Class ;
    rdfs:label "endogenous transposase levels increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000745 .

obo:WBPhenotype_0001773
    obo:IAO_0000115 "Animals do not exhibit an increase in speed when placed in an environment that relies on a combination of swimming and crawling behaviors compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001773" ;
    a owl:Class ;
    rdfs:label "enhanced locomotion defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001206 .

obo:WBPhenotype_0001774
    obo:IAO_0000115 "An epidermal enclosure defect that results in internal organs lying on the outside of the embryo." ;
    oboInOwl:hasExactSynonym "Gex" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001774" ;
    a owl:Class ;
    rdfs:label "gut on the exterior" ;
    rdfs:subClassOf obo:WBPhenotype_0000047 .

obo:WBPhenotype_0001775
    obo:IAO_0000115 "Pre-treatment with stress-inducing temperatures does not result in a life-span extension as it does in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001775" ;
    a owl:Class ;
    rdfs:label "hormetic temperature induced life span extension defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0000146 .

obo:WBPhenotype_0001776
    obo:IAO_0000115 "Variations in the biogenesis and stability of the small interfering class of RNA molecules compared to control. In C. elegans these molecules are antisense to mRNA's and may be processed from long double-stranded RNA." ;
    oboInOwl:hasNarrowSynonym "siRNA expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001776" ;
    a owl:Class ;
    rdfs:label "siRNA expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0001777
    obo:IAO_0000115 "Animals exhibit an increase in the levels of nuclear mRNA species compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001777" ;
    a owl:Class ;
    rdfs:label "pre mRNA levels increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0001778
    obo:IAO_0000115 "Animals fail to silence nuclear-localized RNAs. Animals still retain sensitivity to RNAi for those RNAs located outside of the nucleus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001778" ;
    a owl:Class ;
    rdfs:label "nuclear RNAi defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 .

obo:WBPhenotype_0001779
    obo:IAO_0000115 "Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts." ;
    oboInOwl:hasNarrowSynonym "miRNA expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001779" ;
    a owl:Class ;
    rdfs:label "miRNA expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0001780
    obo:IAO_0000115 "Variations in the behavioral plasticity induced by the integration of two sensory signals compared to control. In C. elegans animals exhibit enhancement of butanone chemotaxis by preexposure to butanone and food." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001780" ;
    a owl:Class ;
    rdfs:label "associative learning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008306
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001781
    obo:IAO_0000115 "Animals are more susceptible than control animals to the effects of a nucleic acid damaging agent. This increased susceptibility is often measured by an increase in the rate of spontaneous mutations or an increased lethality." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001781" ;
    a owl:Class ;
    rdfs:label "hypersensitivity to mutagen" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_25435
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001782
    obo:IAO_0000115 "Response to trace levels of oxygen is reduced or weakened compared to the response of control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001782" ;
    a owl:Class ;
    rdfs:label "anoxia response attenuated" ;
    rdfs:subClassOf obo:WBPhenotype_0002424 .

obo:WBPhenotype_0001783
    obo:IAO_0000115 "Animals exhibit variations in the actions of a channel that catalyses the transmembrane transfer of a cation when acetylcholine has been bound by the channel complex or one of its constituent parts compared to control animals." ;
    oboInOwl:hasNarrowSynonym "ligand gated channel activity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001783" ;
    a owl:Class ;
    rdfs:label "ligand gated channel activity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0000656, obo:WBPhenotype_0001833 .

obo:WBPhenotype_0001784
    obo:IAO_0000115 "OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes." ;
    obo:IAO_0100001 obo:WBPhenotype_0002562 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001784" ;
    a owl:Class ;
    rdfs:label "obsolete lysosome homeostasis deficient" ;
    owl:deprecated true .

obo:WBPhenotype_0001785
    obo:IAO_0000115 "Animals are deficient in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001785" ;
    a owl:Class ;
    rdfs:label "associative memory defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002564 .

obo:WBPhenotype_0001786
    obo:IAO_0000115 "Animals exhibit variations in the targeting, clustering and or maintenance of ion channels in distinct subcellular domains of the neuron compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001786" ;
    a owl:Class ;
    rdfs:label "neuronal ion channel clustering defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000612, obo:WBPhenotype_0002563 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0045161
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001787
    obo:IAO_0000115 "Animals do not respond via directed movement to light stimuli in the same manner as control animals. In C. elegans, animals move away from light." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001787" ;
    a owl:Class ;
    rdfs:label "phototaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001897 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042331
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001788
    obo:IAO_0000115 "Animals survive longer than control animals after or during exposure to DNA damaging agents." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001788" ;
    a owl:Class ;
    rdfs:label "resistant to mutagens" ;
    rdfs:subClassOf obo:WBPhenotype_0000577, obo:WBPhenotype_0000739 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_25435
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001789
    obo:IAO_0000115 "Life span of the animal is not influenced by changes in temperature in the same manner as control animals." ;
    oboInOwl:hasNarrowSynonym "temperature independent life span", "temperature influenced life span abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001789" ;
    a owl:Class ;
    rdfs:label "temperature influenced life span variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0000146 .

obo:WBPhenotype_0001790
    obo:IAO_0000115 "Cooling or warming evoked changes in membrane currents are not observed." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ThRC absent" ;
    oboInOwl:id "WBPhenotype:0001790" ;
    a owl:Class ;
    rdfs:label "thermoreceptor currents absent" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 .

obo:WBPhenotype_0001791
    obo:IAO_0000115 "Animals exhibit variations in temperature dependent differences in the length of their defecation cycle. In C. elegans the length of the cycle is the same at different temperatures, showing temperature compensation." ;
    oboInOwl:hasNarrowSynonym "defecation cycle temperature compensation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001791" ;
    a owl:Class ;
    rdfs:label "defecation cycle temperature compensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000207 .

obo:WBPhenotype_0001792
    obo:IAO_0000115 "Nuclei of specific cells are smaller compared to control animals." ;
    oboInOwl:hasExactSynonym "nuclear size decreased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001792" ;
    a owl:Class ;
    rdfs:label "nuclei small" ;
    rdfs:subClassOf obo:WBPhenotype_0002607 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000587
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005634
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001793
    obo:IAO_0000115 "The anterior body contraction and expulsion steps of the defecation cycle are absent; posterior body contractions are still present." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Aex" ;
    oboInOwl:id "WBPhenotype:0001793" ;
    a owl:Class ;
    rdfs:label "aboc expulsion missing" ;
    rdfs:subClassOf obo:WBPhenotype_0000391 .

obo:WBPhenotype_0001794
    obo:IAO_0000115 "Discrete foci within the cytoplasm containing congregations of mRNA translational suppression and degradation mechanisms vary in their arrangement, clustering or are otherwise not well-defined compared to control." ;
    oboInOwl:hasNarrowSynonym "cytoplasmic processing body abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "P body abnormal" ;
    oboInOwl:id "WBPhenotype:0001794" ;
    a owl:Class ;
    rdfs:label "cytoplasmic processing body variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001300 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000932
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001795
    obo:IAO_0000115 "Animals exhibit variations in repeat lengths of microsatellite genomic sequences compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001795" ;
    a owl:Class ;
    rdfs:label "microsatellite instability" ;
    rdfs:subClassOf obo:WBPhenotype_0000000 .

obo:WBPhenotype_0001796
    obo:IAO_0000115 "Animals exhibit increased sensitivity to interstrand cross-linking agents, such as HN2 (nitrogen mustard) and CDDP (cisplatin) compared to control. In C. elegans, increased sensitivity to these agents is often observed as a decrease in survival compared to control animals after exposure to the agent." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "interstrand cross link agent hypersensitive" ;
    oboInOwl:id "WBPhenotype:0001796" ;
    a owl:Class ;
    rdfs:label "organism hypersensitive interstrand cross link agents" ;
    rdfs:subClassOf obo:WBPhenotype_0000067 .

obo:WBPhenotype_0001797
    obo:IAO_0000115 "Germline nuclei do not progress through pachytene to diplotene." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001797" ;
    a owl:Class ;
    rdfs:label "pachytene arrested germline nuclei" ;
    rdfs:subClassOf obo:WBPhenotype_0001946 .

obo:WBPhenotype_0001798
    obo:IAO_0000115 "The processes that inhibit the location or frequency of formation of synapses are downregulated resulting in the formation of synapses or synapse-like structures in areas of the neuron that are typically devoid of synapses in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001798" ;
    a owl:Class ;
    rdfs:label "inhibition of synaptogenesis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000625, obo:WBPhenotype_0000944 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051964
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001799
    obo:IAO_0000115 "The processes that inhibit the location or frequency of formation of synapses are upregulated compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001799" ;
    a owl:Class ;
    rdfs:label "inhibition of synaptogenesis hyperactive" ;
    rdfs:subClassOf obo:WBPhenotype_0000944 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051964
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001800
    obo:IAO_0000115 "Changes in the levels of innate immune gene products in response to pathogen exposure are significantly different from that observed in control animals." ;
    oboInOwl:hasNarrowSynonym "antimicrobial gene expression abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001800" ;
    a owl:Class ;
    rdfs:label "pathogen induced antimicrobial gene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001857, obo:WBPhenotype_0002164, obo:WBPhenotype_0002534 .

obo:WBPhenotype_0001801
    obo:IAO_0000115 "Animals fail to establish or maintain characteristics that delineate the dendrite from the axon. The exclusion of presynaptic components from the dendrite is one indication of axodendritic polarity." ;
    oboInOwl:hasNarrowSynonym "axodendritic polarity abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001801" ;
    a owl:Class ;
    rdfs:label "axodendritic polarity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000944 .

obo:WBPhenotype_0001802
    obo:IAO_0000115 "Animals fail to relax their body wall muscles to the same extent as muscles in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001802" ;
    a owl:Class ;
    rdfs:label "body wall muscle relaxation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000596 .

obo:WBPhenotype_0001803
    obo:IAO_0000115 "Animals exhibit variations in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ;
    oboInOwl:hasNarrowSynonym "endosome biogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001803" ;
    a owl:Class ;
    rdfs:label "endosome biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 .

obo:WBPhenotype_0001804
    obo:IAO_0000115 "Animals exhibit a decrease in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by decreases in the number of Nile Red or BODIPY 493/503 staining bodies." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid body number reduced" ;
    oboInOwl:id "WBPhenotype:0001804" ;
    a owl:Class ;
    rdfs:label "fat associated bodies reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001901 .

obo:WBPhenotype_0001805
    obo:IAO_0000115 "Inner membrane of mitochondria are disconnected and form vesicular bodies." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001805" ;
    a owl:Class ;
    rdfs:label "mitochondria vesiculated" ;
    rdfs:subClassOf obo:WBPhenotype_0001401 .

obo:WBPhenotype_0001806
    obo:IAO_0000115 "Any variation in the ability of a protein to resist disintegration via chemical or physical modifications compared to control." ;
    oboInOwl:hasNarrowSynonym "protein stabilization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001806" ;
    a owl:Class ;
    rdfs:label "protein stabilization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001644 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0050821
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001807
    obo:IAO_0000115 "Any variation in the process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition compared to control." ;
    oboInOwl:hasNarrowSynonym "alternative splicing abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001807" ;
    a owl:Class ;
    rdfs:label "alternative splicing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000028 .

obo:WBPhenotype_0001808
    obo:IAO_0000115 "The degradation of genomic and or cellular material of the corpse does not occur at the same rate or under the same conditions as observed in control animals undergoing cell death." ;
    oboInOwl:hasNarrowSynonym "cell corpse digestion abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001808" ;
    a owl:Class ;
    rdfs:label "cell corpse digestion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000885 .

obo:WBPhenotype_0001809
    obo:IAO_0000115 "The formation of mature intracellular compartments via membrane fusion is disrupted." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001809" ;
    a owl:Class ;
    rdfs:label "organelle fusion defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0048284
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001810
    obo:IAO_0000115 "Animals exhibit variations in the partitioning of oocytes from each other compared to control animals." ;
    oboInOwl:hasNarrowSynonym "oocyte septum formation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "oocyte cellularization defective", "oocyte partition variant" ;
    oboInOwl:id "WBPhenotype:0001810" ;
    a owl:Class ;
    rdfs:label "oocyte septum formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000399 .

obo:WBPhenotype_0001811
    obo:IAO_0000115 "Animals retain a significantly greater proportion of their fat upon serotonin treatment, compared to control." ;
    oboInOwl:hasNarrowSynonym "serotonin induced fat reduction abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "serotonin induced fat regulation" ;
    oboInOwl:id "WBPhenotype:0001811" ;
    a owl:Class ;
    rdfs:label "serotonin induced fat reduction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001232 .

obo:WBPhenotype_0001812
    obo:IAO_0000115 "During development of the embryo, the epidermis loses integrity and the contents of the embryo are expelled." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001812" ;
    a owl:Class ;
    rdfs:label "embryonic rupture" ;
    rdfs:subClassOf obo:WBPhenotype_0000749 .

obo:WBPhenotype_0001813
    obo:IAO_0000115 "Animals exhibit defects in the stabilization of homologue pairing, which occurs through the initiation and formation of the synaptonemal complex, during meiosis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001813" ;
    a owl:Class ;
    rdfs:label "synapsis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002012 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007129
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001814
    obo:IAO_0000115 "Animals exhibit defects in the number or extent of connections between chromatids that occur during the process of genetic material exchange between homologous segments of non-sister chromatids." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "chiasma defective", "homologous recombination foci variant" ;
    oboInOwl:id "WBPhenotype:0001814" ;
    a owl:Class ;
    rdfs:label "crossover defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002012 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005712
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001815
    obo:IAO_0000115 "Animals exhibit defects in the asymmetric diassembly of the synaptonemal complex during progression through meiosis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001815" ;
    a owl:Class ;
    rdfs:label "desynapsis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002012 .

obo:WBPhenotype_0001816
    obo:IAO_0000115 "Neuromuscular signaling between neurons and egg laying musculature varies from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "egg laying circuit abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001816" ;
    a owl:Class ;
    rdfs:label "egg laying circuit variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000929 .

obo:WBPhenotype_0001817
    obo:IAO_0000115 "The conditioned aversion to a specific chemical compound as a result of that compound being coupled with an unfavorable condition, such as starvation, does not increase to the same extent as observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "enhanced gustatory plasticity defective", "enhanced taste aversion defective", "starvation enhanced taste aversion defective" ;
    oboInOwl:id "WBPhenotype:0001817" ;
    a owl:Class ;
    rdfs:label "enhanced taste aversion defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000147, obo:WBPhenotype_0001444 .

obo:WBPhenotype_0001818
    obo:IAO_0000115 "Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes." ;
    oboInOwl:hasNarrowSynonym "neuron activation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "neuron activity abnormal" ;
    oboInOwl:id "WBPhenotype:0001818" ;
    a owl:Class ;
    rdfs:label "neuron activation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 .

obo:WBPhenotype_0001819
    obo:IAO_0000115 "The number of pathogens associated with the animal vary from that associated with control animals." ;
    oboInOwl:hasNarrowSynonym "bacterial load variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001819" ;
    a owl:Class ;
    rdfs:label "pathogen load variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001012 .

obo:WBPhenotype_0001820
    obo:IAO_0000115 "Animals tend to accumulate at the thickest part of the bacterial lawn." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "bordering increased" ;
    oboInOwl:id "WBPhenotype:0001820" ;
    a owl:Class ;
    rdfs:label "bordering" ;
    rdfs:subClassOf obo:WBPhenotype_0000662, obo:WBPhenotype_0001291 .

obo:WBPhenotype_0001821
    obo:IAO_0000115 "Animals do not accumulate at the thickest part of the bacterial lawn. Animals do not preferentially deplete bacterial food at the thicker parts of the lawn." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001821" ;
    a owl:Class ;
    rdfs:label "non bordering" ;
    rdfs:subClassOf obo:WBPhenotype_0000662, obo:WBPhenotype_0001291 .

obo:WBPhenotype_0001822
    obo:IAO_0000115 "Animals produce pheromone but it does not undergo controlled release into the environment." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001822" ;
    a owl:Class ;
    rdfs:label "dauer pheromone secretion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000258, obo:WBPhenotype_0000609 .

obo:WBPhenotype_0001823
    obo:IAO_0000115 "Any variation in the mechanism by which sperm find their correct target destinations (spermatheca)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001823" ;
    a owl:Class ;
    rdfs:label "sperm recruitment variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001424 .

obo:WBPhenotype_0001824
    obo:IAO_0000115 "Animals exhibit variations in any process necessary for the progression through prophase during meiosis compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001824" ;
    a owl:Class ;
    rdfs:label "meiotic progression prophase variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000313, obo:WBPhenotype_0000775 .

obo:WBPhenotype_0001825
    obo:IAO_0000115 "Animals have very few or no germline nuclei and gonad arms that are very small or missing." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001825" ;
    a owl:Class ;
    rdfs:label "rudimentary gonad" ;
    rdfs:subClassOf obo:WBPhenotype_0001355 .

obo:WBPhenotype_0001826
    obo:IAO_0000115 "Variations in the regulated breakdown of RNA species via the action of cellular enzymes (RNases) compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001826" ;
    a owl:Class ;
    rdfs:label "RNA degradation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000028 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0006401
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001827
    obo:IAO_0000115 "Variations in any process that involves the maintenance, biosynthesis or accumulation of RNA in the organism compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001827" ;
    a owl:Class ;
    rdfs:label "RNA metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000463, obo:WBPhenotype_0000585 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016070
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001828
    obo:IAO_0000115 "Variations in the persistence of an RNAi induced phenotype compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001828" ;
    a owl:Class ;
    rdfs:label "RNAi persistence variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000082
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016246
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001829
    obo:IAO_0000115 "Any variation that results in the premature differentiation of spermatids into motile spermatozoa compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001829" ;
    a owl:Class ;
    rdfs:label "premature spermatid activation" ;
    rdfs:subClassOf obo:WBPhenotype_0000670 .

obo:WBPhenotype_0001830
    obo:IAO_0000115 "Any variation in an animal's response to exposure to multiple stressors occuring simultaneously or during an overlapping temporal window compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001830" ;
    a owl:Class ;
    rdfs:label "response to multiple stressors variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 .

obo:WBPhenotype_0001831
    obo:IAO_0000115 "Any variation in the formation of intestinal microvilli. Microvilli are actin-based cellular structures that form plasma membrane projections into the extracellular space and whose specialized shape provides increased cellular surface area. Microvilli are a crucial component of the terminal differentiation process for many epithelial cell types, usually ones that play an absorptive or filtering role." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001831" ;
    a owl:Class ;
    rdfs:label "intestinal microvilli variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000705 .

obo:WBPhenotype_0001832
    obo:IAO_0000115 "Any variation that disrupts the assembly, distribution, localization or organization of any of the numerous similar discrete openings in the nuclear envelope, where the inner and outer nuclear membranes are joined." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001832" ;
    a owl:Class ;
    rdfs:label "nuclear pore variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002037 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:GO_0005643
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001833
    obo:IAO_0000115 "Any variation in the directed movement of substances in a cell, from one side of a membrane to another, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "membrane transport variant", "transporter activity variant" ;
    oboInOwl:id "WBPhenotype:0001833" ;
    a owl:Class ;
    rdfs:label "membrane trafficking variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0001834
    obo:IAO_0000115 "Variations in the processes regulating the excision of intervening introns from the primary mRNA transcript, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001834" ;
    a owl:Class ;
    rdfs:label "mRNA splicing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000028 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000398
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001835
    obo:IAO_0000115 "Variations in the amount of energy consumed by an organism compared to control. Energy expenditure is often determined by assaying oxygen consumption." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001835" ;
    a owl:Class ;
    rdfs:label "energy expenditure variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0001836
    obo:IAO_0000115 "Any variation in the overall structure or appearance of the protective barrier which isolates the embryo from the external environment, compared to control ." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001836" ;
    a owl:Class ;
    rdfs:label "eggshell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000037 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005843
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001837
    obo:IAO_0000115 "Life span of the animal is not influenced by changes in diet in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001837" ;
    a owl:Class ;
    rdfs:label "diet induced life span variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0002525 .

obo:WBPhenotype_0001838
    obo:IAO_0000115 "Gene expression of an animal is not influenced by drug treatment in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001838" ;
    a owl:Class ;
    rdfs:label "drug induced gene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0001839
    obo:IAO_0000115 "Animals fail to respond to the concentration of phorbol esters that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Phorbol esters such as PMA act as DAG mimetics." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001839" ;
    a owl:Class ;
    rdfs:label "phorbol ester resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_37532
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001840
    obo:IAO_0000115 "Variations in the processes that restore integrity to a damaged tissue following an injury, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "wound healing variant" ;
    oboInOwl:id "WBPhenotype:0001840" ;
    a owl:Class ;
    rdfs:label "response to injury variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009611
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001841
    obo:IAO_0000115 "Any variation in a series of molecular signals that help relay a receptor mediated signal within the cell, compared to control. Second messengers often comprise of ions (eg: Ca2+) or small molecules (cGMP, cAMP etc) that are formed or released into the cytosol." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001841" ;
    a owl:Class ;
    rdfs:label "second messenger mediated signaling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000463 .

obo:WBPhenotype_0001842
    obo:IAO_0000115 "Any variation in the state or activity of an organism as a result of abrupt discontinuation or decreased dosage of a drug, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "rebound response defective" ;
    oboInOwl:id "WBPhenotype:0001842" ;
    a owl:Class ;
    rdfs:label "drug withdrawal response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0001843
    obo:IAO_0000115 "Animals exhibit variations in any process that involves the degradation, biosynthesis or accumulation of hormones within the organism compared to control. Hormones are naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001843" ;
    a owl:Class ;
    rdfs:label "hormone metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0001844
    obo:IAO_0000115 "Variations in the process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "fat granule regulated breakdown variant", "fat granule regulated hydrolysis variant", "lipid lysis regulation variant", "regulation of lipid catabolic process variant" ;
    oboInOwl:id "WBPhenotype:0001844" ;
    a owl:Class ;
    rdfs:label "lipid hydrolysis regulation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000725 .

obo:WBPhenotype_0001845
    obo:IAO_0000115 "Variations in the covalent alteration of one or more components (eg: fatty acids, sterols etc.) in a lipid, resulting in a change in the properties of the lipid, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001845" ;
    a owl:Class ;
    rdfs:label "lipid modification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000725 .

obo:WBPhenotype_0001846
    obo:IAO_0000115 "Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001846" ;
    a owl:Class ;
    rdfs:label "phagosome maturation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000885 .

obo:WBPhenotype_0001847
    obo:IAO_0000115 "Variations in the processes that facilitate/permit dauer entry when exposed to specific sterol molecules, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001847" ;
    a owl:Class ;
    rdfs:label "sterol induced dauer formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001539 .

obo:WBPhenotype_0001848
    obo:IAO_0000115 "Variations in the process by which the anatomical structures of a tube are generated and organized, compared to control. Morphogenesis pertains to the creation of form or shape." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "tubulogenesis variant" ;
    oboInOwl:id "WBPhenotype:0001848" ;
    a owl:Class ;
    rdfs:label "tube morphogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000530 .

obo:WBPhenotype_0001849
    obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of zinc ions within an organism compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001849" ;
    a owl:Class ;
    rdfs:label "zinc homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002029 .

obo:WBPhenotype_0001850
    obo:IAO_0000115 "Programmed cell death of germ cells caused by exposure to ionizing energy does not occur to the same extent as it does in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001850" ;
    a owl:Class ;
    rdfs:label "radiation induced germ cell apoptosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000737, obo:WBPhenotype_0002152 .

obo:WBPhenotype_0001851
    obo:IAO_0000115 "Animals exhibit variations in radiation induced non-apoptotic death of multipotential precursor cells or tissues (clonogens) compared to control. Elimination of clonogens results in normal tissue damage as well as solid-tumor eradication." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001851" ;
    a owl:Class ;
    rdfs:label "radiation induced reproductive cell death variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001173, obo:WBPhenotype_0001268 .

obo:WBPhenotype_0001852
    obo:IAO_0000115 "Animals exhibit variations in their response to an agent that destroys or causes the expulsion of parasitic intestinal worms compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001852" ;
    a owl:Class ;
    rdfs:label "antihelmintic response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000459 .

obo:WBPhenotype_0001853
    obo:IAO_0000115 "Animals exhibit variations in their response to the amino-acetonitrile derivatives (AADs) class of synthetic anthelmintics, compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001853" ;
    a owl:Class ;
    rdfs:label "AAD response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001852 .

obo:WBPhenotype_0001854
    obo:IAO_0000115 "Animals exhibit variations in their response to the microtubule-depolymerizing drug benomyl, compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001854" ;
    a owl:Class ;
    rdfs:label "benomyl response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1901561
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001855
    obo:IAO_0000115 "Animals fail to respond to the concentration of fluoride ions that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to fluoride ions to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001855" ;
    a owl:Class ;
    rdfs:label "fluoride resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001502 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_17051
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001856
    obo:IAO_0000115 "Animals exhibit variations in their response to ivermectin, an agonist of glutamate-gated chloride channels, compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001856" ;
    a owl:Class ;
    rdfs:label "ivermectin response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0001852 .

obo:WBPhenotype_0001857
    obo:IAO_0000115 "Gene expression of an animal is not influenced by the exposure to disease causing agents in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001857" ;
    a owl:Class ;
    rdfs:label "pathogen induced gene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000717, obo:WBPhenotype_0001012 .

obo:WBPhenotype_0001858
    obo:IAO_0000115 "Animals fail to suppress head oscillations in response to anterior touch. In C. elegans, this behavior is a result of tyraminergic signaling." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Sho" ;
    oboInOwl:id "WBPhenotype:0001858" ;
    a owl:Class ;
    rdfs:label "suppression of head oscillations defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000595 .

obo:WBPhenotype_0001859
    obo:IAO_0000115 "Any variation in the aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "DCC localization variant" ;
    oboInOwl:id "WBPhenotype:0001859" ;
    a owl:Class ;
    rdfs:comment "Possible xp." ;
    rdfs:label "Dosage compensation complex assembly variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000718 .

obo:WBPhenotype_0001860
    obo:IAO_0000115 "Variations in the directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001860" ;
    a owl:Class ;
    rdfs:label "endocytic recycling defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001422 .

obo:WBPhenotype_0001861
    obo:IAO_0000115 "Gene expression of an animal is not influenced by environmental changes in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001861" ;
    a owl:Class ;
    rdfs:label "environmental stimuli induced gene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0001862
    obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of manganese ions within an organism compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001862" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "manganese homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002029 .

obo:WBPhenotype_0001863
    obo:IAO_0000115 "Animals exhibit variations in their response to manganese compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001863" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "manganese response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010042
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001864
    obo:IAO_0000115 "Any variation in the processes that modulate the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001864" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "protein transport variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001644, obo:WBPhenotype_0001833 .

obo:WBPhenotype_0001865
    obo:IAO_0000115 "Variations in the process by which one or more ubiquitin moieties are added to a protein, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "protein ubiquitylation variant" ;
    oboInOwl:id "WBPhenotype:0001865" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "protein ubiquitination variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 .

obo:WBPhenotype_0001866
    obo:IAO_0000115 "Animals exhibit a reduction in pathogen accumulation, persistent colonization, and luminal distension of the intestine." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Rpa" ;
    oboInOwl:id "WBPhenotype:0001866" ;
    a owl:Class ;
    rdfs:label "reduced pathogen accumulation" ;
    rdfs:subClassOf obo:WBPhenotype_0001819 .

obo:WBPhenotype_0001867
    obo:IAO_0000115 "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a mitotic cell cycle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001867" ;
    a owl:Class ;
    rdfs:label "mitotic spindle asters defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001102, obo:WBPhenotype_0001110 .

obo:WBPhenotype_0001868
    obo:IAO_0000115 "Cells undergoing meiosis exhibit defects in the overall function or activity of the meiotic spindle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001868" ;
    a owl:Class ;
    rdfs:label "meiotic spindle defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000775 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001624
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0072687
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001869
    obo:IAO_0000115 "Cells undergoing meiosis exhibit defects in the positioning of the meiotic spindle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001869" ;
    a owl:Class ;
    rdfs:label "meiotic spindle positioning defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001868 .

obo:WBPhenotype_0001870
    obo:IAO_0000115 "Cells undergoing meiosis exhibit defects in the rotation of the meiotic spindle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001870" ;
    a owl:Class ;
    rdfs:label "meiotic spindle rotation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001868 .

obo:WBPhenotype_0001871
    obo:IAO_0000115 "Life span of the animal is not influenced by drug exposure in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001871" ;
    a owl:Class ;
    rdfs:label "drug induced life span variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0000631 .

obo:WBPhenotype_0001872
    obo:IAO_0000115 "Locomotion of the animal is not influenced by drug exposure in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001872" ;
    a owl:Class ;
    rdfs:label "drug induced locomotion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0001873
    obo:IAO_0000115 "Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the meiotic spindle, the array of microtubules and associated molecules that serves to move duplicated and/or homologous chromosomes apart." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001873" ;
    a owl:Class ;
    rdfs:label "meiotic spindle assembly defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001868 .

obo:WBPhenotype_0001874
    obo:IAO_0000115 "Any variation in the conjugation of the ubiquitin-like protein Nedd8 to another protein compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001874" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "protein neddylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 .

obo:WBPhenotype_0001875
    obo:IAO_0000115 "Chromosomal masses fail to fully separate and remained linked during anaphase." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "chromosome bridging", "lagging chromatin" ;
    oboInOwl:id "WBPhenotype:0001875" ;
    a owl:Class ;
    rdfs:label "anaphase bridging" ;
    rdfs:subClassOf obo:WBPhenotype_0001378 .

obo:WBPhenotype_0001876
    obo:IAO_0000115 "Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001876" ;
    a owl:Class ;
    rdfs:label "centriole biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001903 .

obo:WBPhenotype_0001877
    obo:IAO_0000115 "Any variation in the structure, form or composition of the membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001877" ;
    a owl:Class ;
    rdfs:label "nuclear membrane morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002037 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0031965
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001878
    obo:IAO_0000115 "Animals exhibit variations in the response to the addition of hydroxyurea compared to that observed in control animals. Hydroxyurea stops DNA from being replicated." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "HU response variant", "hydroxycarbamide response variant" ;
    oboInOwl:id "WBPhenotype:0001878" ;
    a owl:Class ;
    rdfs:label "hydroxyurea response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0072710
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001879
    obo:IAO_0000115 "Animals respond to hydroxyurea at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001879" ;
    a owl:Class ;
    rdfs:label "hydroxyurea hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001878 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_44423
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001880
    obo:IAO_0000115 "Any variation in the form, structure or composition of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001880" ;
    a owl:Class ;
    rdfs:label "endoplasmic reticulum morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005783
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001881
    obo:IAO_0000115 "Any variation in the normally asymmetric distribution of the endoplasmic reticulum during cell divisions of the early embryo. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001881" ;
    a owl:Class ;
    rdfs:label "endoplasmic reticulum symmetry variant early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001880 .

obo:WBPhenotype_0001882
    obo:IAO_0000115 "Any variation in the number of chromosomes in a cell compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001882" ;
    a owl:Class ;
    rdfs:label "aneuploidy" ;
    rdfs:subClassOf obo:WBPhenotype_0000773 .

obo:WBPhenotype_0001885
    obo:IAO_0000115 "Embryos exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001885" ;
    a owl:Class ;
    rdfs:label "cleavage furrow initiation defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001129 .

obo:WBPhenotype_0001886
    obo:IAO_0000115 "Embryos exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001886" ;
    a owl:Class ;
    rdfs:label "cleavage furrow termination defective early emb" ;
    rdfs:subClassOf obo:WBPhenotype_0001129 .

obo:WBPhenotype_0001887
    obo:IAO_0000115 "Animals execute supernumerary cell divisions during the development of the lateral, alae-producing epithelial cells, resulting in a larger number of these cells than control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001887" ;
    a owl:Class ;
    rdfs:label "excess seam cells" ;
    rdfs:subClassOf obo:WBPhenotype_0002175, obo:WBPhenotype_0002569 .

obo:WBPhenotype_0001888
    obo:IAO_0000115 "Animals exhibit an increase in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by increases in the number of BODIPY 493/503 staining." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid body number increased", "lipid droplet expansion" ;
    oboInOwl:id "WBPhenotype:0001888" ;
    a owl:Class ;
    rdfs:label "fat associated bodies increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001901 .

obo:WBPhenotype_0001889
    obo:IAO_0000115 "Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001889" ;
    a owl:Class ;
    rdfs:label "body wall muscle sarcomere morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000926 .

obo:WBPhenotype_0001890
    obo:IAO_0000115 "Any variation in the attachment plaque for thin filaments onto the cell membrane. The dense body in body wall muscles is especially large, indenting far into the cytoplasm to border each sarcomere, thus providing a long row of coherent attachment sites at regular intervals (WormAtlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001890" ;
    a owl:Class ;
    rdfs:label "body wall muscle dense body variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001889 .

obo:WBPhenotype_0001891
    obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001891" ;
    a owl:Class ;
    rdfs:label "M line variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001889 .

obo:WBPhenotype_0001892
    obo:IAO_0000115 "Any variation in the levels of the polymerized form of glucose throughout the body of the animal as compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001892" ;
    a owl:Class ;
    rdfs:label "glycogen levels variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_28087
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001893
    obo:IAO_0000115 "Any reduction in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001893" ;
    a owl:Class ;
    rdfs:label "mitochondrial membrane potential reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001282 .

obo:WBPhenotype_0001894
    obo:IAO_0000115 "Animals exhibit variations in the number of nuclei contained in a particular cell type compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001894" ;
    a owl:Class ;
    rdfs:label "nuclear number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000504 .

obo:WBPhenotype_0001895
    obo:IAO_0000115 "Parental chromosomes fail to undergo appropriate mixing upon pronuclear fusion resulting in a zygotic nucleus in which parental genomes remain segregated." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "pronuclear fusion defective" ;
    oboInOwl:id "WBPhenotype:0001895" ;
    a owl:Class ;
    rdfs:label "parental chromosome mixing defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001138 .

obo:WBPhenotype_0001896
    obo:IAO_0000115 "Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001896" ;
    a owl:Class ;
    rdfs:label "gamma ray induced apoptosis decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000182, obo:WBPhenotype_0001326 .

obo:WBPhenotype_0001897
    obo:IAO_0000115 "Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus (electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light) compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Lite" ;
    oboInOwl:id "WBPhenotype:0001897" ;
    a owl:Class ;
    rdfs:label "light response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009416
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001898
    obo:IAO_0000115 "Variations in the process by which sister chromatids, identical chromosomes resulting from DNA replication, are physically separated during the meiotic cell cycle, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001898" ;
    a owl:Class ;
    rdfs:label "meiotic sister chromatid segregation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001499 .

obo:WBPhenotype_0001899
    obo:IAO_0000115 "Animals exhibit variations in the amount of glutathione compared to control animals at a defined stage. Glutathione, the tripeptide glutamylcysteinylglycine, acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001899" ;
    a owl:Class ;
    rdfs:label "glutathione levels variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_16856
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001900
    obo:IAO_0000115 "Animals exhibit a decrease in the cellular levels of reduced glutathione (GSH), compared to control. Reduced levels of GSH may be an indication of susceptibility to oxidative stress." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "reduced levels of GSH" ;
    oboInOwl:id "WBPhenotype:0001900" ;
    a owl:Class ;
    rdfs:label "reduced levels of reduced glutathione" ;
    rdfs:subClassOf obo:WBPhenotype_0001899 .

obo:WBPhenotype_0001901
    obo:IAO_0000115 "Animals exhibit variations in the formation or disassembly of fat containing organelles compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid body variant" ;
    oboInOwl:id "WBPhenotype:0001901" ;
    a owl:Class ;
    rdfs:label "fat associated bodies variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 .

obo:WBPhenotype_0001902
    obo:IAO_0000115 "Animals exhibit an increase in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid body size increased" ;
    oboInOwl:id "WBPhenotype:0001902" ;
    a owl:Class ;
    rdfs:label "fat associated body size increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001901 .

obo:WBPhenotype_0001903
    obo:IAO_0000115 "Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix).  The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001903" ;
    a owl:Class ;
    rdfs:label "centrosome biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 .

obo:WBPhenotype_0001904
    obo:IAO_0000115 "Animals fail to exhibit toxicity to the concentration of manganese that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to manganese include dopamine (DA) neuron neurodegeneration." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001904" ;
    a owl:Class ;
    rdfs:label "manganese toxicity resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001863 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_18291
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001905
    obo:IAO_0000115 "Animals lay fewer total number of eggs over the lifetime of the animal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001905" ;
    a owl:Class ;
    rdfs:label "fewer eggs laid" ;
    rdfs:subClassOf obo:WBPhenotype_0000640 .

obo:WBPhenotype_0001906
    obo:IAO_0000115 "During epidermal morphogenesis, hypodermal cells do not properly undergo the characteristic cell shape changes necessary for the embryo to elongate." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001906" ;
    a owl:Class ;
    rdfs:label "hypodermal cell elongation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002569 .

obo:WBPhenotype_0001907
    obo:IAO_0000115 "Animals exhibit defects in the generation of the dorsal epithelial sheet, which entails distinct cell shape changes and movements to affect the interdigitation of two rows of dorsal cells resulting in a single row of cells across the dorsal midline." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001907" ;
    a owl:Class ;
    rdfs:label "dorsal intercalation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002569 .

obo:WBPhenotype_0001908
    obo:IAO_0000115 "The animal displays defects in any step of the ventral enclosure process resulting an embryo that is not enclosed and or with interior cells protruding out of the embryo." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001908" ;
    a owl:Class ;
    rdfs:label "ventral closure defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001566 .

obo:WBPhenotype_0001909
    obo:IAO_0000115 "OBSOLETE. Any variation in the prevention of mRNA translation that normally occurs in certain cells, compared to control." ;
    obo:IAO_0100001 obo:WBPhenotype_0002157 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001909" ;
    a owl:Class ;
    rdfs:label "obsolete translational repression variant" ;
    owl:deprecated true .

obo:WBPhenotype_0001910
    obo:IAO_0000115 "Animals exhibit variations in the assembly, arrangement, orientation, or disassembly of the kinetochore, a multisubunit protein complex on chromosomes where the spindle fibers attach during cell division to pull the chromosomes apart." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001910" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "kinetochore organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001348 .

obo:WBPhenotype_0001911
    obo:IAO_0000115 "Animals do not regrow axons following axon loss or damage, to the same extent, or in the same manner as observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001911" ;
    a owl:Class ;
    rdfs:label "axon regeneration defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000880 .

obo:WBPhenotype_0001912
    obo:IAO_0000115 "The number of coelomocytes are reduced compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001912" ;
    a owl:Class ;
    rdfs:label "fewer coelomocytes" ;
    rdfs:subClassOf obo:WBPhenotype_0000618, obo:WBPhenotype_0002174 .

obo:WBPhenotype_0001913
    obo:IAO_0000115 "The number of coelomocytes are increased compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001913" ;
    a owl:Class ;
    rdfs:label "excess coelomocytes" ;
    rdfs:subClassOf obo:WBPhenotype_0000618, obo:WBPhenotype_0002175 .

obo:WBPhenotype_0001914
    obo:IAO_0000115 "Animals contain fewer pharyngeal cells compared to control animals.  In C. elegans, pharyngeal cells are derived from MS-blastomere." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001914" ;
    a owl:Class ;
    rdfs:label "fewer pharyngeal cells" ;
    rdfs:subClassOf obo:WBPhenotype_0000707, obo:WBPhenotype_0002174 .

obo:WBPhenotype_0001915
    obo:IAO_0000115 "Any variation that results in the cellular expression of an mRNA in cells/tissues, that is otherwise not observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001915" ;
    a owl:Class ;
    rdfs:label "mRNA expression ectopic" ;
    rdfs:subClassOf obo:WBPhenotype_0000114 .

obo:WBPhenotype_0001916
    obo:IAO_0000115 "Pathogens internally associated with the animal exhibit an increase in survival compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001916" ;
    a owl:Class ;
    rdfs:label "increased pathogen survival" ;
    rdfs:subClassOf obo:WBPhenotype_0001819 .

obo:WBPhenotype_0001917
    obo:IAO_0000115 "Variations in the processes that incorporate acetyl groups to one or more amino acids within a protein, compared to control. An acetyl group is CH3CO-." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001917" ;
    a owl:Class ;
    rdfs:label "protein acetylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 .

obo:WBPhenotype_0001918
    obo:IAO_0000115 "Animals respond to a specific chemical at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001918" ;
    a owl:Class ;
    rdfs:label "chemical hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000523 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_24431
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001919
    obo:IAO_0000115 "Animals exhibit larger inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001919" ;
    a owl:Class ;
    rdfs:label "gut granules enlarged" ;
    rdfs:subClassOf obo:WBPhenotype_0002240 .

obo:WBPhenotype_0001920
    obo:IAO_0000115 "The growth of pharyngeal components occurs in a radial fashion around the longitudinal axis of the worm as demonstrated by bent radial contractile arrays within the pharyngeal muscle cells. The defect is more pronounced as development progresses resulting in a more obvious twisting phenotype. Depending on the allele, the twist can be right-handed or left-handed" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Twp", "pharynx twisted" ;
    oboInOwl:id "WBPhenotype:0001920" ;
    a owl:Class ;
    rdfs:label "twisted pharynx" ;
    rdfs:subClassOf obo:WBPhenotype_0000707 .

obo:WBPhenotype_0001921
    obo:IAO_0000115 "Any variation in the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001921" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "meiotic DNA double strand break formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000775 .

obo:WBPhenotype_0001922
    obo:IAO_0000115 "Any variation in the directed movement of organelles or molecules along microtubules in nerve cell axons." ;
    oboInOwl:hasExactSynonym "axon transport variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "axon cargo transport variant" ;
    oboInOwl:id "WBPhenotype:0001922" ;
    a owl:Class ;
    rdfs:comment "Possible XP." ;
    rdfs:label "axonal transport variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 .

obo:WBPhenotype_0001923
    obo:IAO_0000115 "The population of the lateral, alae-producing epithelial cells (seam cells) is reduced compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001923" ;
    a owl:Class ;
    rdfs:label "fewer seam cells" ;
    rdfs:subClassOf obo:WBPhenotype_0002174, obo:WBPhenotype_0002569 .

obo:WBPhenotype_0001924
    obo:IAO_0000115 "Oocytes are found one on top of the other in the dorsal to ventral orientation in the gonad." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001924" ;
    a owl:Class ;
    rdfs:label "oocytes stacked" ;
    rdfs:subClassOf obo:WBPhenotype_0001260 .

obo:WBPhenotype_0001925
    obo:IAO_0000115 "Oocytes are no longer arranged in the gonad in the same manner as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001925" ;
    a owl:Class ;
    rdfs:label "oocytes disorganized" ;
    rdfs:subClassOf obo:WBPhenotype_0001260 .

obo:WBPhenotype_0001926
    obo:IAO_0000115 "Basal contraction rate and or peak contraction rate of the gonadal sheath is increased relative to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001926" ;
    a owl:Class ;
    rdfs:label "gonad sheath contraction rate increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001199 .

obo:WBPhenotype_0001927
    obo:IAO_0000115 "Animals produce an excess number of distal tip cells compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001927" ;
    a owl:Class ;
    rdfs:label "extra distal tip cells" ;
    rdfs:subClassOf obo:WBPhenotype_0001656, obo:WBPhenotype_0002175 .

obo:WBPhenotype_0001928
    obo:IAO_0000115 "Animals produce an excess number of gonad arms compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001928" ;
    a owl:Class ;
    rdfs:label "extra gonad arms" ;
    rdfs:subClassOf obo:WBPhenotype_0000399 .

obo:WBPhenotype_0001929
    obo:IAO_0000115 "The gonads of male animals do not produce the linker cell involved in guiding the developing male gonad to the sex organs in the male tail." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001929" ;
    a owl:Class ;
    rdfs:label "linker cell absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001675, obo:WBPhenotype_0002174 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005062
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001930
    obo:IAO_0000115 "Animals extend altered or fewer numbers of dorsal and or ventral muscle arms compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Madd", "muscle arm extension defective" ;
    oboInOwl:id "WBPhenotype:0001930" ;
    a owl:Class ;
    rdfs:label "muscle arm development defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000540 .

obo:WBPhenotype_0001931
    obo:IAO_0000115 "The morphology or number of connections between muscle arms and commissural motor axons varies from control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001931" ;
    a owl:Class ;
    rdfs:label "muscle arm axon connection variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000540 .

obo:WBPhenotype_0001932
    obo:IAO_0000115 "Animals exhibit ectopic plasma membrane extensions from muscle, these extensions are random projections that are thinner than the typical muscle arm." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001932" ;
    a owl:Class ;
    rdfs:label "myopodia present" ;
    rdfs:subClassOf obo:WBPhenotype_0000904 .

obo:WBPhenotype_0001933
    obo:IAO_0000115 "The pattern of localization of presynaptic markers is disrupted compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Sam" ;
    oboInOwl:id "WBPhenotype:0001933" ;
    a owl:Class ;
    rdfs:label "synaptic vesicle tag abnormal in mechanosensory neurons" ;
    rdfs:subClassOf obo:WBPhenotype_0000847 .

obo:WBPhenotype_0001934
    obo:IAO_0000115 "Any variation in the extension of vulval muscles compared to control.  In C. elegans contralateral vulval muscles fail to meet at the midline." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Vme" ;
    oboInOwl:id "WBPhenotype:0001934" ;
    a owl:Class ;
    rdfs:label "vulval muscle extension variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001314 .

obo:WBPhenotype_0001935
    obo:IAO_0000115 "Animals become paralyzed in response to aggregation of proteins like poly-glutamine or beta-amyloid." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001935" ;
    a owl:Class ;
    rdfs:label "protein aggregation induced paralysis" ;
    rdfs:subClassOf obo:WBPhenotype_0002425 .

obo:WBPhenotype_0001936
    obo:IAO_0000115 "Animals fail to respond to the aggregation of proteins that elicits a paralysis response in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001936" ;
    a owl:Class ;
    rdfs:label "resistant to protein aggregation induced paralysis" ;
    rdfs:subClassOf obo:WBPhenotype_0001935 .

obo:WBPhenotype_0001937
    obo:IAO_0000115 "Animals respond to protein aggregation at a lower concentration of aggregates or in less time compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001937" ;
    a owl:Class ;
    rdfs:label "hypersensitive to protein aggregation induced paralysis" ;
    rdfs:subClassOf obo:WBPhenotype_0001935 .

obo:WBPhenotype_0001938
    obo:IAO_0000115 "Any variation in the process of restoring DNA after damage.  DNA damage can be caused by a many chemical or physical agents, and this damage is repaired by a variety  of different DNA repair pathways." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001938" ;
    a owl:Class ;
    rdfs:label "DNA repair variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000732 .

obo:WBPhenotype_0001939
    obo:IAO_0000115 "Animals are not repelled by bitter tastants such as quinine, primaquine quinacrine etc., to the same extent as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001939" ;
    a owl:Class ;
    rdfs:label "bitter tastant response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001450 .

obo:WBPhenotype_0001940
    obo:IAO_0000115 "Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "rachis morphology abnormal" ;
    oboInOwl:id "WBPhenotype:0001940" ;
    a owl:Class ;
    rdfs:label "rachis morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001355 .

obo:WBPhenotype_0001941
    obo:IAO_0000115 "The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001941" ;
    a owl:Class ;
    rdfs:label "rachis narrow" ;
    rdfs:subClassOf obo:WBPhenotype_0001940 .

obo:WBPhenotype_0001942
    obo:IAO_0000115 "The nucleus-free core of germline cytoplasm in the gonad is missing." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001942" ;
    a owl:Class ;
    rdfs:label "rachis absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001940 .

obo:WBPhenotype_0001943
    obo:IAO_0000115 "The width of the nucleus-free core of germline cytoplasm in the gonad is larger compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001943" ;
    a owl:Class ;
    rdfs:label "rachis wide" ;
    rdfs:subClassOf obo:WBPhenotype_0001940 .

obo:WBPhenotype_0001944
    obo:IAO_0000115 "A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "fewer oocytes" ;
    oboInOwl:id "WBPhenotype:0001944" ;
    a owl:Class ;
    rdfs:label "oocyte number decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000186, obo:WBPhenotype_0001260 .

obo:WBPhenotype_0001945
    obo:IAO_0000115 "The size of haploid female germ cells (oocytes) are significantly smaller compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001945" ;
    a owl:Class ;
    rdfs:label "oocytes small" ;
    rdfs:subClassOf obo:WBPhenotype_0001260 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000587
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006797
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001946
    obo:IAO_0000115 "Developing oocytes show defects in their entry, progression through or exit from the pachytene stage compared to control animals. Pachytene is a cell cycle process comprising the steps by which a cell progresses through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001946" ;
    a owl:Class ;
    rdfs:label "pachytene progression during oogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001824 .

obo:WBPhenotype_0001947
    obo:IAO_0000115 "Developing oocytes show defects in their entry, progression through or exit from the diplotene stage compared to control animals. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001947" ;
    a owl:Class ;
    rdfs:label "diplotene progression during oogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001824 .

obo:WBPhenotype_0001948
    obo:IAO_0000115 "Developing oocytes show defects in their entry, progression through or exit from the diakinesis stage compared to control animals. Diakinesis is a cell cycle process comprising the steps by which a cell progresses through the final stage of prophase I in meiosis; the transition to meiotic metaphase I." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001948" ;
    a owl:Class ;
    rdfs:label "diakinesis progression during oogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001824 .

obo:WBPhenotype_0001949
    obo:IAO_0000115 "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diakinesis stage. In C. elegans the diakinesis region occurs in the proximal gonad arm and is preceded by the diplotene region. In the diakinesis region oocytes arrest until oocyte maturation occurs." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001949" ;
    a owl:Class ;
    rdfs:label "diakinesis region organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001355, obo:WBPhenotype_0001948 .

obo:WBPhenotype_0001950
    obo:IAO_0000115 "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001950" ;
    a owl:Class ;
    rdfs:label "diplotene region organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001355, obo:WBPhenotype_0001947 .

obo:WBPhenotype_0001951
    obo:IAO_0000115 "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001951" ;
    a owl:Class ;
    rdfs:label "pachytene region organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001355, obo:WBPhenotype_0001946 .

obo:WBPhenotype_0001952
    obo:IAO_0000115 "Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "germline nuclear migration variant" ;
    oboInOwl:id "WBPhenotype:0001952" ;
    a owl:Class ;
    rdfs:label "germline nuclear positioning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000511 .

obo:WBPhenotype_0001953
    obo:IAO_0000115 "Nuclei have fallen out of developing germ cell compartments into the rachis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001953" ;
    a owl:Class ;
    rdfs:label "nuclear fallout" ;
    rdfs:subClassOf obo:WBPhenotype_0001952 .

obo:WBPhenotype_0001954
    obo:IAO_0000115 "The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001954" ;
    a owl:Class ;
    rdfs:label "diplotene absent during oogenesis" ;
    rdfs:subClassOf obo:WBPhenotype_0001947 .

obo:WBPhenotype_0001955
    obo:IAO_0000115 "Haploid female germ cells (oocytes) contain more than one nucleus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "multinucleate oocyte" ;
    oboInOwl:id "WBPhenotype:0001955" ;
    a owl:Class ;
    rdfs:label "multiple nuclei oocyte" ;
    rdfs:subClassOf obo:WBPhenotype_0000186, obo:WBPhenotype_0001260, obo:WBPhenotype_0002413 .

obo:WBPhenotype_0001956
    obo:IAO_0000115 "Haploid female germ cells (oocytes) lack a nucleus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "anucleate oocytes" ;
    oboInOwl:id "WBPhenotype:0001956" ;
    a owl:Class ;
    rdfs:label "oocytes lack nucleus" ;
    rdfs:subClassOf obo:WBPhenotype_0000186, obo:WBPhenotype_0001260 .

obo:WBPhenotype_0001957
    obo:IAO_0000115 "A decrease in size of the specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001957" ;
    a owl:Class ;
    rdfs:label "gonad small" ;
    rdfs:subClassOf obo:WBPhenotype_0001355 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000587
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005175
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001958
    obo:IAO_0000115 "Animals contain a gonad that initially functioned, but subsequently stopped.  In hermaphrodites or females there is often the presence old embryos and/or hatched larva, but no young embryos, in the uterus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "degenerate gonad" ;
    oboInOwl:id "WBPhenotype:0001958" ;
    a owl:Class ;
    rdfs:label "gonad degenerate" ;
    rdfs:subClassOf obo:WBPhenotype_0001355 .

obo:WBPhenotype_0001959
    obo:IAO_0000115 "Pulling forces on the astral microtubules at the spindle poles vary from that observed for control spindles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001959" ;
    a owl:Class ;
    rdfs:label "spindle pole pulling force variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002414 .

obo:WBPhenotype_0001960
    obo:IAO_0000115 "The spindle in the early embryo is aberrant in the characteristic posterior aster oscillations that occur along the transverse longitudinal axis of the spindle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001960" ;
    a owl:Class ;
    rdfs:label "spindle oscillation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002414 .

obo:WBPhenotype_0001961
    obo:IAO_0000115 "Animals continue to produce progeny significantly past the time reproduction stops in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001961" ;
    a owl:Class ;
    rdfs:label "reproductive longevity extended" ;
    rdfs:subClassOf obo:WBPhenotype_0001739 .

obo:WBPhenotype_0001962
    obo:IAO_0000115 "Animals produce less distal tip cells compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001962" ;
    a owl:Class ;
    rdfs:label "missing distal tip cells" ;
    rdfs:subClassOf obo:WBPhenotype_0001656, obo:WBPhenotype_0002174 .

obo:WBPhenotype_0001963
    obo:IAO_0000115 "The association of homologs during diakinesis and the maintenance of their association through meiosis I as well as the preservation of centromeric cohesin between sister chromatids does not proceed as it does in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001963" ;
    a owl:Class ;
    rdfs:label "homolog association variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001824 .

obo:WBPhenotype_0001964
    obo:IAO_0000115 "Animals exhibit differential regulation of the dopaminergic fate among the various classes of dopaminergic neurons." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Dopy" ;
    oboInOwl:id "WBPhenotype:0001964" ;
    a owl:Class ;
    rdfs:label "dopaminergic fate atypical" ;
    rdfs:subClassOf obo:WBPhenotype_0001510 .

obo:WBPhenotype_0001965
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of the cell, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001965" ;
    a owl:Class ;
    rdfs:label "cell membrane physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0001966
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of within the cell, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001966" ;
    a owl:Class ;
    rdfs:label "cell endomembrane physiology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001965 .

obo:WBPhenotype_0001967
    obo:IAO_0000115 "Animals differ from control animals in the length of or mechanics of the steps that culminate in the preservation and subsequent disassembly of the synaptonemal complex, the specification of bivalent arms, and proper cohesion of sister chromatids." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001967" ;
    a owl:Class ;
    rdfs:label "meiotic chromatin reorganization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002012 .

obo:WBPhenotype_0001968
    obo:IAO_0000115 "All somatic gonad precursor (SGP) daughters adopt a proximal fate resulting in an increase in the number of AC precursor cells at the expense of distal tip cells (DTC), which are thereby absent." ;
    oboInOwl:hasBroadSynonym "Sys" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "symmetrical sisters" ;
    oboInOwl:id "WBPhenotype:0001968" ;
    a owl:Class ;
    rdfs:label "somatic gonad precursor symmetrical sisters" ;
    rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0001235 .

obo:WBPhenotype_0001969
    obo:IAO_0000115 "Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis).  These compartments eventually undergo cellularization and become oocytes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001969" ;
    a owl:Class ;
    rdfs:label "germ cell compartment morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000900 .

obo:WBPhenotype_0001970
    obo:IAO_0000115 "Germ cell compartments contain an an atypical number on nuclei compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001970" ;
    a owl:Class ;
    rdfs:label "germ cell compartment nuclei number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001969 .

obo:WBPhenotype_0001971
    obo:IAO_0000115 "Germ cell compartments do not contain a nucleus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001971" ;
    a owl:Class ;
    rdfs:label "germ cell compartment anucleate" ;
    rdfs:subClassOf obo:WBPhenotype_0001970 .

obo:WBPhenotype_0001972
    obo:IAO_0000115 "Germ cell compartments contain multiple nuclei." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001972" ;
    a owl:Class ;
    rdfs:label "germ cell compartment multinucleate" ;
    rdfs:subClassOf obo:WBPhenotype_0001970 .

obo:WBPhenotype_0001973
    obo:IAO_0000115 "Any variation in germ cell compartment size compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001973" ;
    a owl:Class ;
    rdfs:label "germ cell compartment size variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001969 .

obo:WBPhenotype_0001974
    obo:IAO_0000115 "Germ cell compartments are smaller than that of control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001974" ;
    a owl:Class ;
    rdfs:label "germ cell compartment small" ;
    rdfs:subClassOf obo:WBPhenotype_0001973 .

obo:WBPhenotype_0001975
    obo:IAO_0000115 "Germ cell compartments are larger than that of control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001975" ;
    a owl:Class ;
    rdfs:label "germ cell compartment large" ;
    rdfs:subClassOf obo:WBPhenotype_0001973 .

obo:WBPhenotype_0001976
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0001978 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001976" ;
    a owl:Class ;
    owl:deprecated true .

obo:WBPhenotype_0001977
    obo:IAO_0000115 "Any variation in the form or composition of the compartment partitions in the germline of females/hermaphrodites that exist when nuclei are still connected to a common cytoplasm (rachis), compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001977" ;
    a owl:Class ;
    rdfs:label "germ cell partition morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001969 .

obo:WBPhenotype_0001978
    obo:IAO_0000115 "Animals lack germ cell partitions (germ cell compartments)." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001976" ;
    oboInOwl:hasExactSynonym "germ cell compartment absent" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001978" ;
    a owl:Class ;
    rdfs:label "germ cell partition absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001977 .

obo:WBPhenotype_0001979
    obo:IAO_0000115 "Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001979" ;
    a owl:Class ;
    rdfs:label "gonad vesiculated" ;
    rdfs:subClassOf obo:WBPhenotype_0001355 .

obo:WBPhenotype_0001980
    obo:IAO_0000115 "Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001980" ;
    a owl:Class ;
    rdfs:label "germ cell compartment expansion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001969 .

obo:WBPhenotype_0001981
    obo:IAO_0000115 "The compartments of the germline do not increase in size." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001981" ;
    a owl:Class ;
    rdfs:label "germ cell compartment expansion absent" ;
    rdfs:subClassOf obo:WBPhenotype_0001980 .

obo:WBPhenotype_0001982
    obo:IAO_0000115 "Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001982" ;
    a owl:Class ;
    rdfs:label "cell membrane organization biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0010002 .

obo:WBPhenotype_0001983
    obo:IAO_0000115 "Variation of the time an individual spent on a patch of food (bacterial lawn) before leaving, compared to control animals." ;
    oboInOwl:hasExactSynonym "food leaving behavior variant", "patch leaving behavior variant" ;
    oboInOwl:hasNarrowSynonym "exploratory behavior variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "exploration behavior variant" ;
    oboInOwl:id "WBPhenotype:0001983" ;
    a owl:Class ;
    rdfs:label "lawn leaving behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000662 .

obo:WBPhenotype_0001984
    obo:IAO_0000115 "Animals exhibit axons with migration behaviors that differ from those observed in control animals after the axons cross a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001984" ;
    a owl:Class ;
    rdfs:label "long range axon migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001224 .

obo:WBPhenotype_0001985
    obo:IAO_0000115 "Animals exhibit axons with migration behaviors that differ from those observed in control animals before the axons reach a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001985" ;
    a owl:Class ;
    rdfs:label "short range axon migration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001224 .

obo:WBPhenotype_0001986
    obo:IAO_0000115 "Animals undergo an irreversible high temperature-induced developmental arrest during the first larval stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001986" ;
    a owl:Class ;
    rdfs:label "high temperature induced L1 arrest" ;
    rdfs:subClassOf obo:WBPhenotype_0000081, obo:WBPhenotype_0001273 .

obo:WBPhenotype_0001987
    obo:IAO_0000115 "Any variation in the measured levels of acetylcholinesterase (AChE) activity compared to control animals." ;
    oboInOwl:hasExactSynonym "acetylcholinesterase class activity variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001987" ;
    a owl:Class ;
    rdfs:label "acetylcholinesterase activity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000124 .

obo:WBPhenotype_0001988
    obo:IAO_0000115 "Animals respond to a detergent at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001988" ;
    a owl:Class ;
    rdfs:label "detergent hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001918 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_27780
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0001989
    obo:IAO_0000115 "Animals respond to hypoxic (low oxygen levels) stress after a shorter exposure time compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001989" ;
    a owl:Class ;
    rdfs:label "hypoxia hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0002423 .

obo:WBPhenotype_0001990
    obo:IAO_0000115 "Animals fail to respond to low amounts of oxygen that elicit a response in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001990" ;
    a owl:Class ;
    rdfs:label "hypoxia resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0002423 .

obo:WBPhenotype_0001991
    obo:IAO_0000115 "Response to low levels of oxygen is reduced or weakened compared to the response of control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001991" ;
    a owl:Class ;
    rdfs:label "hypoxia response attenuated" ;
    rdfs:subClassOf obo:WBPhenotype_0002423 .

obo:WBPhenotype_0001992
    obo:IAO_0000115 "Animals exhibit an increase in the number of somatic sheath cells surrounding each gonad arm compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001992" ;
    a owl:Class ;
    rdfs:label "extra gonadal sheath cells" ;
    rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0002175 .

obo:WBPhenotype_0001993
    obo:IAO_0000115 "Animals exhibit fewer somatic sheath cells surrounding each gonad arm, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001993" ;
    a owl:Class ;
    rdfs:label "fewer gonadal sheath cells" ;
    rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0002174 .

obo:WBPhenotype_0001994
    obo:IAO_0000115 "Any variation in the establishment of left-right asymmetry of the body axis compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "left right asymmetry variant" ;
    oboInOwl:id "WBPhenotype:0001994" ;
    a owl:Class ;
    rdfs:label "left right handedness variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000578 .

obo:WBPhenotype_0001995
    obo:IAO_0000115 "Cells of the animals exhibit variations in the progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001995" ;
    a owl:Class ;
    rdfs:label "cell cycle progression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000740 .

obo:WBPhenotype_0001996
    obo:IAO_0000115 "Any variation in the cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence before entering the S phase, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001996" ;
    a owl:Class ;
    rdfs:label "cell cycle quiescence variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001995 .

obo:WBPhenotype_0001997
    obo:IAO_0000115 "The nucleus or nuclei are not positioned in a similar manner or pattern in the cell or syncytium to that observed in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001997" ;
    a owl:Class ;
    rdfs:label "nuclear anchoring variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000511 .

obo:WBPhenotype_0001998
    obo:IAO_0000115 "Animals respond more severely to laser ablation than control animals subjected to the same laser ablation conditions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001998" ;
    a owl:Class ;
    rdfs:label "hypersensitive to laser ablation" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0001999
    obo:IAO_0000115 "Animals behave differently from control animals in assays testing for the ability to resolve or respond to conflicting sensory inputs." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0001999" ;
    a owl:Class ;
    rdfs:label "conflicting sensory integration variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 .

obo:WBPhenotype_0002000
    obo:IAO_0000115 "Animals that exhibit an increase in locomotion activity do not return to basal level locomotion activity at the same rate as that of control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002000" ;
    a owl:Class ;
    rdfs:label "recovery from enhanced locomotion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000641 .

obo:WBPhenotype_0002001
    obo:IAO_0000115 "The number of synapses per unit area of a neuron differs in the animal compared to that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002001" ;
    a owl:Class ;
    rdfs:label "synapse density variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000604 .

obo:WBPhenotype_0002002
    obo:IAO_0000115 "A cell or cell of the animal exhibits extra centrosomes (a subcellular body consisting of two centrioles embedded in a protein matrix) compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002002" ;
    a owl:Class ;
    rdfs:label "supernumerary centrosomes" ;
    rdfs:subClassOf obo:WBPhenotype_0001903 .

obo:WBPhenotype_0002003
    obo:IAO_0000115 "Animals exhibit variations in steady-state levels of hydrogen peroxide (H2O2) compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002003" ;
    a owl:Class ;
    rdfs:label "hydrogen peroxide homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0002004
    obo:IAO_0000115 "Animals exhibit defects in the flow rate or targeting of the cortical actomyosin network, which occurs during polarization as well as contraction of the contractile ring, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002004" ;
    a owl:Class ;
    rdfs:label "actomyosin contractility defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000034, obo:WBPhenotype_0001587, obo:WBPhenotype_0002408 .

obo:WBPhenotype_0002005
    obo:IAO_0000115 "The tension of the cytoskeleton comprised of the actomyosin network differs from controls. This tension can be measured by laser-cutting of the actomyosin cytoskeleton and observing any differences the recoil velocity of cortex adjacent to the cut site." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002005" ;
    a owl:Class ;
    rdfs:label "actomyosin cytoskeletal tension variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001346 .

obo:WBPhenotype_0002006
    obo:IAO_0000115 "Compared to controls, embryos exhibit variations in the part meiosis I in which homologous chromosomes separate and migrate away from each other." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002006" ;
    a owl:Class ;
    rdfs:label "anaphase I progression variant early embryo" ;
    rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0002389 .

obo:WBPhenotype_0002007
    obo:IAO_0000115 "Embryos display cortical protusions during cytokinesis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002007" ;
    a owl:Class ;
    rdfs:label "cortical blebs present" ;
    rdfs:subClassOf obo:WBPhenotype_0000764, obo:WBPhenotype_0002408 .

obo:WBPhenotype_0002008
    obo:IAO_0000115 "Animals exhibit variations in the non-enzymatic glycosylation process of attaching a protein or lipid to a sugar molecule, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002008" ;
    a owl:Class ;
    rdfs:label "glycation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0002009
    obo:IAO_0000115 "Animals exhibit variations from controls in their protein degradation machinery, which functions through the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002009" ;
    a owl:Class ;
    rdfs:label "proteasome core activity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001644 .

obo:WBPhenotype_0002010
    obo:IAO_0000115 "The dynamics of the replacement of old proteins by newly synthesized or modified proteins varies from that of control animals. This phenotype is often measured by fluorescence recovery after photobleaching (FRAP)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002010" ;
    a owl:Class ;
    rdfs:label "protein turnover variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001644 .

obo:WBPhenotype_0002011
    obo:IAO_0000115 "Animals exhibit a secondary vulval invagination that is anterior or posterior to the primary opening depending on the the inappropriate placement of daughter cells along the anterior/posterior axis during vulval development." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002011" ;
    a owl:Class ;
    rdfs:label "bivulva" ;
    rdfs:subClassOf obo:WBPhenotype_0000695 .

obo:WBPhenotype_0002012
    obo:IAO_0000115 "Any variation in the process of chromosome organization that is involved in meiosis, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002012" ;
    a owl:Class ;
    rdfs:label "meiotic chromosome organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000775 .

obo:WBPhenotype_0002013
    obo:IAO_0000115 "Chromosomes fails to pair with homologous chromosomes during the prophase stage of meiosis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002013" ;
    a owl:Class ;
    rdfs:label "univalent meiotic chromosomes" ;
    rdfs:subClassOf obo:WBPhenotype_0002012 .

obo:WBPhenotype_0002014
    obo:IAO_0000115 "Any observed variation in the measurement of current across the cell membrane compared to measurements in control animals. Current is a flow of electric charge through a medium." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002014" ;
    a owl:Class ;
    rdfs:label "current measurement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001315 .

obo:WBPhenotype_0002015
    obo:IAO_0000115 "Any observed variation in the measurement of voltage across the cell membrane compared to measurements in control animals. Voltage is the difference in electric potential energy per unit charge between two points." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002015" ;
    a owl:Class ;
    rdfs:label "voltage measurement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001315 .

obo:WBPhenotype_0002016
    obo:IAO_0000115 "Failure to execute the characteristic response to biotin as defined by control animals. In C. elegans, biotin is typically an attractant." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002016" ;
    a owl:Class ;
    rdfs:label "biotin chemotaxis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001441 .

obo:WBPhenotype_0002017
    obo:IAO_0000115 "Any variation in the ability of multipotent vulval precursor cells to respond to signals compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "vulval precursor cell competence abnormal", "vulval precursor cell competence variant" ;
    oboInOwl:id "WBPhenotype:0002017" ;
    a owl:Class ;
    rdfs:label "VPC competence variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000216 .

obo:WBPhenotype_0002018
    obo:IAO_0000115 "Seam cells fuse to form a continuous syncytium along the body wall at a later stage of development compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002018" ;
    a owl:Class ;
    rdfs:label "retarded seam cell fusion" ;
    rdfs:subClassOf obo:WBPhenotype_0000166 .

obo:WBPhenotype_0002019
    obo:IAO_0000115 "Adult animals display a smaller number of eggs inside the uterus compared to controls" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002019" ;
    a owl:Class ;
    rdfs:label "fewer eggs in utero" ;
    rdfs:subClassOf obo:WBPhenotype_0000624 .

obo:WBPhenotype_0002020
    obo:IAO_0000115 "Transmission of the signal along the neuron varies from control.  This process includes the flow of information from the neuron cell body to the synapse and across to the postsynaptic cell." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002020" ;
    a owl:Class ;
    rdfs:label "transmission of nerve impulse variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000612 .

obo:WBPhenotype_0002021
    obo:IAO_0000115 "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed at the synapse, which are independent of presynaptic inputs." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002021" ;
    a owl:Class ;
    rdfs:label "synaptic spike frequency variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000584, obo:WBPhenotype_0002023 .

obo:WBPhenotype_0002022
    obo:IAO_0000115 "Calcium transients at presynaptic regions do not occur." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002022" ;
    a owl:Class ;
    rdfs:label "no synaptic spike frequency" ;
    rdfs:subClassOf obo:WBPhenotype_0002021 .

obo:WBPhenotype_0002023
    obo:IAO_0000115 "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed either at the cell body or the synaptic region, which are independent of presynaptic inputs." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002023" ;
    a owl:Class ;
    rdfs:label "spike frequency variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002020 .

obo:WBPhenotype_0002024
    obo:IAO_0000115 "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed in cell bodies, which are independent of presynaptic inputs." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002024" ;
    a owl:Class ;
    rdfs:label "cell body spike frequency variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002023 .

obo:WBPhenotype_0002025
    obo:IAO_0000115 "The diameter, volume, or area taken up by a cell differs from that measured in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002025" ;
    a owl:Class ;
    rdfs:label "cell size decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000533 .

obo:WBPhenotype_0002026
    obo:IAO_0000115 "Animals differ from control animals in response to mechanical stimulation targeting different parts of the same cell. In N2 wild-type animals, response to touch near the ALM cell body is reduced compared with touch of the cell area near the second pharyngeal bulb." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002026" ;
    a owl:Class ;
    rdfs:label "differential touch sensitivity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0002027
    obo:IAO_0000115 "VPCs differentiate in the absence of inductive signals coming from the gonad." ;
    oboInOwl:hasExactSynonym "Gid" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002027" ;
    a owl:Class ;
    rdfs:label "gonad independent vulva differentiation" ;
    rdfs:subClassOf obo:WBPhenotype_0000354, obo:WBPhenotype_0001272 .

obo:WBPhenotype_0002028
    obo:IAO_0000115 "Animals differ from controls in their electrical response to mechanical stimulus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "MRC variant" ;
    oboInOwl:id "WBPhenotype:0002028" ;
    a owl:Class ;
    rdfs:label "mechanoreceptor current variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0002029
    obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of metal ions within an organism compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002029" ;
    a owl:Class ;
    rdfs:label "metal homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0002030
    obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of magnesium ions within an organism compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002030" ;
    a owl:Class ;
    rdfs:label "magnesium homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002029 .

obo:WBPhenotype_0002031
    obo:IAO_0000115 "Exposure to carbohydrate binding gene products result in an altered action in comparison to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002031" ;
    a owl:Class ;
    rdfs:label "lectin response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000459, obo:WBPhenotype_0001210 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_1990840
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002032
    obo:IAO_0000115 "Animals differ from controls in the range, specificity, or presence of targets for exogenously applied lectins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002032" ;
    a owl:Class ;
    rdfs:label "lectin binding variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002031 .

obo:WBPhenotype_0002033
    obo:IAO_0000115 "Animals contain targets for exogenously applied lectins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ectopic lectin binding" ;
    oboInOwl:id "WBPhenotype:0002033" ;
    a owl:Class ;
    rdfs:label "lectin binding occurs" ;
    rdfs:subClassOf obo:WBPhenotype_0002031 .

obo:WBPhenotype_0002034
    obo:IAO_0000115 "Animals are not observed to contain targets for exogenously applied lectins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002034" ;
    a owl:Class ;
    rdfs:label "lectin binding does not occur" ;
    rdfs:subClassOf obo:WBPhenotype_0002031 .

obo:WBPhenotype_0002035
    obo:IAO_0000115 "Exposure to lectin has no affect on the behavior, growth, or development of the animal compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002035" ;
    a owl:Class ;
    rdfs:label "resistant to lectin" ;
    rdfs:subClassOf obo:WBPhenotype_0002031 .

obo:WBPhenotype_0002036
    obo:IAO_0000115 "Exposure to lectin results in altered behavior, growth, or development of the animal compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002036" ;
    a owl:Class ;
    rdfs:label "susceptible to lectin" ;
    rdfs:subClassOf obo:WBPhenotype_0002031 .

obo:WBPhenotype_0002037
    obo:IAO_0000115 "The appearance and association of components along the double lipid bilayer enclosing the nucleus differs from controls. The NE separates nuclear contents from the rest of the cytoplasm and includes the intermembrane space, perinuclear space." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002037" ;
    a owl:Class ;
    rdfs:label "nuclear envelope organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001028 .

obo:WBPhenotype_0002038
    obo:IAO_0000115 "Proteins show defects in their localization in the cilia compared to control animals." ;
    oboInOwl:hasBroadSynonym "cil" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002038" ;
    a owl:Class ;
    rdfs:label "ciliary localization defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000851 .

obo:WBPhenotype_0002039
    obo:IAO_0000115 "Animals exhibit variation in the directed movement of organelles or molecules along microtubules from the cell periphery in nerve cell axons to the cell body, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002039" ;
    a owl:Class ;
    rdfs:label "retrograde transport variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 .

obo:WBPhenotype_0002040
    obo:IAO_0000115 "Chromosomes are not segregated symmetrically during mitosis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "chaotic mitosis" ;
    oboInOwl:id "WBPhenotype:0002040" ;
    a owl:Class ;
    rdfs:label "asymmetric chromosome segregation" ;
    rdfs:subClassOf obo:WBPhenotype_0001378 .

obo:WBPhenotype_0002041
    obo:IAO_0000115 "Animals exhibit variation in timing or ability to molt." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002041" ;
    a owl:Class ;
    rdfs:label "molt variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000750 .

obo:WBPhenotype_0002042
    obo:IAO_0000115 "Molting cycles do not occur in a temporally controlled manner and cannot be synchronized across a population." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002042" ;
    a owl:Class ;
    rdfs:label "molting arrhythmic" ;
    rdfs:subClassOf obo:WBPhenotype_0002041 .

obo:WBPhenotype_0002043
    obo:IAO_0000115 "The number of cross progeny produced by hermaphrodites is reduced compared to control hermaphrodites." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002043" ;
    a owl:Class ;
    rdfs:label "hermaphrodite mating efficiency reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0004001 .

obo:WBPhenotype_0002044
    obo:IAO_0000115 "Hermaphrodites do not produce cross progeny." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002044" ;
    a owl:Class ;
    rdfs:label "hermaphrodite mating efficiency eliminated" ;
    rdfs:subClassOf obo:WBPhenotype_0002043 .

obo:WBPhenotype_0002045
    obo:IAO_0000115 "Animals exhibit fewer cell corpses compared to controls at the same developmental life stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002045" ;
    a owl:Class ;
    rdfs:label "cell corpse number decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000590 .

obo:WBPhenotype_0002046
    obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of iron within an organism compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002046" ;
    a owl:Class ;
    rdfs:label "iron homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002029 .

obo:WBPhenotype_0002047
    obo:IAO_0000115 "Animals exhibit variations in their response to muscimol compared to that observed in control animals. Muscimol is a GABA-A receptor agonist." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002047" ;
    a owl:Class ;
    rdfs:label "muscimol response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0002048
    obo:IAO_0000115 "Animals survive longer, or do not respond to the same degree as control animals under similar conditions of abamectin exposure." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002048" ;
    a owl:Class ;
    rdfs:label "abamectin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0002049 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_39214
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002049
    obo:IAO_0000115 "Animals are not affected to the same degree as control animals under similar conditions of abamectin exposure." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002049" ;
    a owl:Class ;
    rdfs:label "abamectin repsonse variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0001852 .

obo:WBPhenotype_0002050
    obo:IAO_0000115 "Animals are do not survive, or become paralyzed in the presence of abamectin." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002050" ;
    a owl:Class ;
    rdfs:label "abamectin sensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0002049 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_39214
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002051
    obo:IAO_0000115 "The production or regulation of ascaroside molecule populations differs from that of control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002051" ;
    a owl:Class ;
    rdfs:label "ascaroside biosynthesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0002052
    obo:IAO_0000115 "Animals lack the ability to produce ascarosides that are capable of being produced in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002052" ;
    a owl:Class ;
    rdfs:label "ascaroside biosynthesis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002051 .

obo:WBPhenotype_0002053
    obo:IAO_0000115 "Animals fail to respond to or exhibit an attenuated response to ivermectin under conditions that elicits a response in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002053" ;
    a owl:Class ;
    rdfs:label "ivermectin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001856 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_6078
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002054
    obo:IAO_0000115 "Animals exhibit an exaggerated response to magnesium compared to control animals exposed to similar concentrations." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002054" ;
    a owl:Class ;
    rdfs:label "magnesium hypersensitivity" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_25107
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002055
    obo:IAO_0000115 "Animals do not exhibit light-induced currrents to the same extent or with the same quality as control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002055" ;
    a owl:Class ;
    rdfs:label "photocurrent defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002014 .

obo:WBPhenotype_0002056
    obo:IAO_0000115 "Any variation in the specific actions or reactions of an organism causing an alteration in the ingestion of food compared to control animals.  In C. elegans the main food source is bacteria and alterations in eating behavior usually lead to malnutrition." ;
    oboInOwl:hasExactSynonym "Eat" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002056" ;
    a owl:Class ;
    rdfs:label "eating variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000659 .

obo:WBPhenotype_0002057
    obo:IAO_0000115 "Animals respond to Bacillus thuringiensis toxins (Bt toxins) at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002057" ;
    a owl:Class ;
    rdfs:label "Bacillus thuringiensis toxin hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 .

obo:WBPhenotype_0002058
    obo:IAO_0000115 "Animals are not affected to the same degree as control animals under similar conditions of pore forming toxin exposure." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002058" ;
    a owl:Class ;
    rdfs:label "pore forming toxin response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0035915
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002059
    obo:IAO_0000115 "Animals respond to pore forming toxins at a lower concentration or a shorter exposure compared to control animals. Increased susceptibility to pore forming toxins (e.g. Cry5B from Bacillus thuringiensis) is often measured by a decrease in the rate of survival in the presence of pore forming toxins compared to controls." ;
    oboInOwl:hasBroadSynonym "Hpo" ;
    oboInOwl:hasExactSynonym "hypersensitive to pore forming toxin" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002059" ;
    a owl:Class ;
    rdfs:label "pore forming toxin hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0002058 .

obo:WBPhenotype_0002060
    obo:IAO_0000115 "Animals fail to respond to the concentration of pore forming toxins that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002060" ;
    a owl:Class ;
    rdfs:label "pore forming toxin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0002058 .

obo:WBPhenotype_0002061
    obo:IAO_0000115 "Any variation in the progressive decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002061" ;
    a owl:Class ;
    rdfs:label "chromosome decondensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0002062
    obo:IAO_0000115 "The process of decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form is abolished." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002062" ;
    a owl:Class ;
    rdfs:label "chromosome decondensation failure" ;
    rdfs:subClassOf obo:WBPhenotype_0002061 .

obo:WBPhenotype_0002063
    obo:IAO_0000115 "Animals differ from controls in the expression of genes targeted for silencing (gene inactivation) in subsequent generations via transcriptional or post-transcriptional processes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002063" ;
    a owl:Class ;
    rdfs:label "maintenance of gene silencing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0002064
    obo:IAO_0000115 "Animals express genes that had been targeted for heritable silencing in previous generations." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002064" ;
    a owl:Class ;
    rdfs:label "maintenance of gene silencing defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002063 .

obo:WBPhenotype_0002065
    obo:IAO_0000115 "Animals display variations in the manner in which the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) is remodeled, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002065" ;
    a owl:Class ;
    rdfs:label "basement membrane remodeling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000200, obo:WBPhenotype_0002588 .

obo:WBPhenotype_0002066
    obo:IAO_0000115 "Animals display variations in the manner in which an opening in the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) expands to make way for intertissue connections, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002066" ;
    a owl:Class ;
    rdfs:label "basement membrane gap expansion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002065 .

obo:WBPhenotype_0002067
    obo:IAO_0000115 "Animals differ from control animals in cortical actomyocin dynamics leading to internalization of endodermal precursor cells during gastrulation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002067" ;
    a owl:Class ;
    rdfs:label "apical constriction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000047 .

obo:WBPhenotype_0002068
    obo:IAO_0000115 "There is significantly less difference between the number of astral microtubles or other component(s) of the spindle microtuble organizing center at the anterior versus posterior poles of the spindle, than observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002068" ;
    a owl:Class ;
    rdfs:label "astral microtubule asymmetry defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002419 .

obo:WBPhenotype_0002069
    obo:IAO_0000115 "Axons in animals do not end in the same manner as they do in control animals. Some defects described include an overextension of the axon or termination of the axon in the shape of a hook, either large or small." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002069" ;
    a owl:Class ;
    rdfs:label "axon termination defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000180 .

obo:WBPhenotype_0002070
    obo:IAO_0000115 "Animals do not mimic control animals in their egg-laying response to muscimol exposure. In C. elegans, muscimol inhibits egg-laying." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002070" ;
    a owl:Class ;
    rdfs:label "egg laying response to muscimol variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001101, obo:WBPhenotype_0002047 .

obo:WBPhenotype_0002071
    obo:IAO_0000115 "The length of the animal does not increase to the same extent as observed for control animals, in response to exposure to muscimol." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002071" ;
    a owl:Class ;
    rdfs:label "body lengthening response to muscimol variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002047 .

obo:WBPhenotype_0002072
    obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of carbohydrates within the organism or cell compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002072" ;
    a owl:Class ;
    rdfs:label "carbohydrate metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0002073
    obo:IAO_0000115 "Animals exhibit variations in the regulation of levels, transport, and metabolism of cations within a cell or between a cell and its external environment, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002073" ;
    a owl:Class ;
    rdfs:label "cation homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0002074
    obo:IAO_0000115 "Animals vary in the directed or coordinated movement of their centrosomes during cell division, compared to the pattern of movement observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002074" ;
    a owl:Class ;
    rdfs:label "centrosome dynamics variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0002075
    obo:IAO_0000115 "Embryos exhibit variations in the processes that lead to the construction of the eggshell, a protective structure that minimizes water loss whilst allowing gas exchanges essential for embryonic respiration, compared to controls" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002075" ;
    a owl:Class ;
    rdfs:label "eggshell formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000041, obo:WBPhenotype_0000258 .

obo:WBPhenotype_0002076
    obo:IAO_0000115 "The process of secretion by a cell that results in the release of intracellular molecules contained within a specialized secretory vesicle that fuses with the plasma membrane during egg activation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002076" ;
    a owl:Class ;
    rdfs:label "cortical granule exocytosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002075 .

obo:WBPhenotype_0002077
    obo:IAO_0000115 "Animals fail to respond to the concentration of a dopamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002077" ;
    a owl:Class ;
    rdfs:label "dopamine resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000011 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_18243
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002078
    obo:IAO_0000115 "The pattern or state of methyl modifications of histone varies from that of controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "methylation mark variant" ;
    oboInOwl:id "WBPhenotype:0002078" ;
    a owl:Class ;
    rdfs:label "histone methylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001383 .

obo:WBPhenotype_0002079
    obo:IAO_0000115 "The animal's ability to reproduce, or start of reproduction occurs later than that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002079" ;
    a owl:Class ;
    rdfs:label "delayed reproductive maturity" ;
    rdfs:subClassOf obo:WBPhenotype_0000045 .

obo:WBPhenotype_0002080
    obo:IAO_0000115 "Animals exhibit variations in the degree to which or manner in which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002080" ;
    a owl:Class ;
    rdfs:label "peptide uptake by intestinal cell variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001763 .

obo:WBPhenotype_0002081
    obo:IAO_0000115 "Animals exhibit an increase in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002081" ;
    a owl:Class ;
    rdfs:label "peptide uptake by intestinal cell increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002080 .

obo:WBPhenotype_0002082
    obo:IAO_0000115 "Animals exhibit a decrease in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002082" ;
    a owl:Class ;
    rdfs:label "peptide uptake by intestinal cell decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002080 .

obo:WBPhenotype_0002083
    obo:IAO_0000115 "The frequency and distribution of crossover events differs from that observed for controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002083" ;
    a owl:Class ;
    rdfs:label "crossover variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002012 .

obo:WBPhenotype_0002084
    obo:IAO_0000115 "Animals differ from controls in respect to the frequency of expected double crossover events observed." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002084" ;
    a owl:Class ;
    rdfs:label "crossover interference variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002083 .

obo:WBPhenotype_0002085
    obo:IAO_0000115 "The number of crossover events differs from that of observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002085" ;
    a owl:Class ;
    rdfs:label "crossover formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002083 .

obo:WBPhenotype_0002086
    obo:IAO_0000115 "The location-specific frequency of crossover events differs from that of observed in control animals, while the total number of crossover events does not significantly differ." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002086" ;
    a owl:Class ;
    rdfs:label "crossover distribution variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002083 .

obo:WBPhenotype_0002087
    obo:IAO_0000115 "Animals respond to hydrogen sulfide at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002087" ;
    a owl:Class ;
    rdfs:label "hydrogen sulfide hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000010 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_16136
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002088
    obo:IAO_0000115 "Animals respond to dauer pheromone at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002088" ;
    a owl:Class ;
    rdfs:label "hypersensitive to dauer pheromone" ;
    rdfs:subClassOf obo:WBPhenotype_0001479 .

obo:WBPhenotype_0002089
    obo:IAO_0000115 "Any variation in the form or composition of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002089" ;
    a owl:Class ;
    rdfs:label "cell component morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000533 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005575
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002090
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as endosomes,  that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002090" ;
    a owl:Class ;
    rdfs:label "endosome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005768
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002091
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as late endosomes,  that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002091" ;
    a owl:Class ;
    rdfs:label "late endosome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002090 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005770
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002092
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as early endosomes,  that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002092" ;
    a owl:Class ;
    rdfs:label "early endosome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002090 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005769
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002093
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes,  that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002093" ;
    a owl:Class ;
    rdfs:label "recycling endosome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002090 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0055037
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002094
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002094" ;
    a owl:Class ;
    rdfs:label "RAB-11 recycling endosome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002093 .

obo:WBPhenotype_0002095
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002095" ;
    a owl:Class ;
    rdfs:label "lysosome-related organelle morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 .

obo:WBPhenotype_0002096
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002096" ;
    a owl:Class ;
    rdfs:label "golgi apparatus morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005794
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002097
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002097" ;
    a owl:Class ;
    rdfs:label "lysosome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005764
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002098
    obo:IAO_0000115 "Any variation in the subcellular localization of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002098" ;
    a owl:Class ;
    rdfs:label "cell component localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000533 .

obo:WBPhenotype_0002099
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002099" ;
    a owl:Class ;
    rdfs:label "lysosome-related organelle localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002098 .

obo:WBPhenotype_0002100
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as endosomes,  that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002100" ;
    a owl:Class ;
    rdfs:label "endosome localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002098 .

obo:WBPhenotype_0002101
    obo:IAO_0000115 "Any variation in the subcellular localization of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that exists in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002101" ;
    a owl:Class ;
    rdfs:label "endoplasmic reticulum localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002098 .

obo:WBPhenotype_0002102
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002102" ;
    a owl:Class ;
    rdfs:label "golgi apparatus localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002098 .

obo:WBPhenotype_0002103
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002103" ;
    a owl:Class ;
    rdfs:label "lysosome localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002098 .

obo:WBPhenotype_0002104
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes,  that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002104" ;
    a owl:Class ;
    rdfs:label "recycling endosome localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002100 .

obo:WBPhenotype_0002105
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as late endosomes,  that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002105" ;
    a owl:Class ;
    rdfs:label "late endosome localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002100 .

obo:WBPhenotype_0002106
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as early endosomes,  that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002106" ;
    a owl:Class ;
    rdfs:label "early endosome localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002100 .

obo:WBPhenotype_0002107
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002107" ;
    a owl:Class ;
    rdfs:label "RAB-11 recycling endosome localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002104 .

obo:WBPhenotype_0002108
    obo:IAO_0000115 "Any variation in the form or composition of specialized cell types, compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002108" ;
    a owl:Class ;
    rdfs:label "cell type morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000533 .

obo:WBPhenotype_0002109
    obo:IAO_0000115 "Animals are affected by exposure to the drug." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002109" ;
    a owl:Class ;
    rdfs:label "drug susceptible" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0002110
    obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002110" ;
    a owl:Class ;
    rdfs:label "RME-1 recycling endosome morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002093 .

obo:WBPhenotype_0002111
    obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002111" ;
    a owl:Class ;
    rdfs:label "RME-1 recycling endosome localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002104 .

obo:WBPhenotype_0002112
    obo:IAO_0000115 "Animals are unable to maintain paired chromosome throughout pachytene." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002112" ;
    a owl:Class ;
    rdfs:label "synapsis maintenance defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002012 .

obo:WBPhenotype_0002113
    obo:IAO_0000115 "Animals differ from controls in respect to the formation of paired chromosome loci." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002113" ;
    a owl:Class ;
    rdfs:label "synapsis formation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002012 .

obo:WBPhenotype_0002114
    obo:IAO_0000115 "Animals become paralyzed after a measured amount of time swimming. In C. elegans, more then 80 percent of wild-type animals continue swimming vigorously in liquid even after 30 minutes." ;
    oboInOwl:hasBroadSynonym "SWIP" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002114" ;
    a owl:Class ;
    rdfs:label "swimming induced paralysis" ;
    rdfs:subClassOf obo:WBPhenotype_0001700 .

obo:WBPhenotype_0002115
    obo:IAO_0000115 "Animals do not avoid, and perhaps seek, environments that result in their death. In the case of C. elegans, this behavior is exemplified by animals that tend to crawl off the plate." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002115" ;
    a owl:Class ;
    rdfs:label "suicidal" ;
    rdfs:subClassOf obo:WBPhenotype_0000888 .

obo:WBPhenotype_0002116
    obo:IAO_0000115 "Animals are barely alive, but not entirely dead." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002116" ;
    a owl:Class ;
    rdfs:label "subviable" ;
    rdfs:subClassOf obo:WBPhenotype_0000531, obo:WBPhenotype_0000576 .

obo:WBPhenotype_0002117
    obo:IAO_0000115 "Animals exhibit constrictions in the anterior portion of the head that result in decapitation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002117" ;
    a owl:Class ;
    rdfs:label "occurences of decapitation" ;
    rdfs:subClassOf obo:WBPhenotype_0000212 .

obo:WBPhenotype_0002118
    obo:IAO_0000115 "Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations.  In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed." ;
    oboInOwl:hasExactSynonym "population fitness variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002118" ;
    a owl:Class ;
    rdfs:label "population fitness phenotype" ;
    rdfs:subClassOf obo:WBPhenotype_0000519 .

obo:WBPhenotype_0002119
    obo:IAO_0000115 "The process of generating multiple mRNA molecules from differential use of exons in a primary transcript(s) does not occur or occurs with outcomes not observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002119" ;
    a owl:Class ;
    rdfs:label "alternative splicing defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001807 .

obo:WBPhenotype_0002120
    obo:IAO_0000115 "Any variation in the process of restoring mitochondrial DNA after damage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002120" ;
    a owl:Class ;
    rdfs:label "mitochondrial DNA repair variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001938 .

obo:WBPhenotype_0002121
    obo:IAO_0000115 "The presence of a mixture of more than one type of an organellar genome (mitochondrial DNA (mtDNA) or plastid DNA) within a cell or individual." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002121" ;
    a owl:Class ;
    rdfs:label "heteroplasmy" ;
    rdfs:subClassOf obo:WBPhenotype_0000576 .

obo:WBPhenotype_0002122
    obo:IAO_0000115 "Mitochondria from spermatazoa persist in the developing embryo and animal as a result of bypassing the degradation mechanism that normally destroys paternal mitochondria immediately after fertilization. This can often lead to a form of heteroplasmy." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002122" ;
    a owl:Class ;
    rdfs:label "persistence of paternal mitochondria" ;
    rdfs:subClassOf obo:WBPhenotype_0002121 .

obo:WBPhenotype_0002123
    obo:IAO_0000115 "The pattern or state of acetylation modifications of histones varies from that of controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002123" ;
    a owl:Class ;
    rdfs:label "histone acetylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001917 .

obo:WBPhenotype_0002124
    obo:IAO_0000115 "The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002124" ;
    a owl:Class ;
    rdfs:label "circumferential actin bundles disorganized" ;
    rdfs:subClassOf obo:WBPhenotype_0001587 .

obo:WBPhenotype_0002125
    obo:IAO_0000115 "Animals do not grow fast or the quality of growth is decreased when exposed to a specific chemical compound when compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002125" ;
    a owl:Class ;
    rdfs:label "growth inhibition response to chemical" ;
    rdfs:subClassOf obo:WBPhenotype_0000523 .

obo:WBPhenotype_0002126
    obo:IAO_0000115 "Animals exhibit a decrease in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002126" ;
    a owl:Class ;
    rdfs:label "intestinal fluorescence decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000293 .

obo:WBPhenotype_0002127
    obo:IAO_0000115 "Animals exhibit variation rate of directed movement of organelles or molecules along microtubules in nerve cell axons, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002127" ;
    a owl:Class ;
    rdfs:label "intraflagellar transport velocity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000853 .

obo:WBPhenotype_0002128
    obo:IAO_0000115 "Males remain on food in the absence of mates, a defect in male mate-searching behavior observed in control males." ;
    oboInOwl:hasBroadSynonym "Las" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002128" ;
    a owl:Class ;
    rdfs:label "leaving assay defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001983, obo:WBPhenotype_0004031 .

obo:WBPhenotype_0002129
    obo:IAO_0000115 "Relative levels of mtDNA differ from that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002129" ;
    a owl:Class ;
    rdfs:label "mitochondrial DNA copy number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000732, obo:WBPhenotype_0001282 .

obo:WBPhenotype_0002130
    obo:IAO_0000115 "Males exhibit variations of the behaviors observed in control animals that follow the completion of mating." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "mate experience variant" ;
    oboInOwl:id "WBPhenotype:0002130" ;
    a owl:Class ;
    rdfs:label "post mating variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000648 .

obo:WBPhenotype_0002131
    obo:IAO_0000115 "Animals display variations in the structure or organization of the components of the muscle, compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002131" ;
    a owl:Class ;
    rdfs:label "muscle cell ultrastructure variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000904 .

obo:WBPhenotype_0002132
    obo:IAO_0000115 "The formation, organization, or stability of a protein complex is altered in comparison to corresponding complexes in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "protein clustering variant" ;
    oboInOwl:id "WBPhenotype:0002132" ;
    a owl:Class ;
    rdfs:label "protein complex organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001370 .

obo:WBPhenotype_0002133
    obo:IAO_0000115 "The bulk flow of cytoplasm in the egg, that facilitates mixing of ooplasm, occurs at a reduced rate compared to that measured for controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002133" ;
    a owl:Class ;
    rdfs:label "ooplasmic streaming slow" ;
    rdfs:subClassOf obo:WBPhenotype_0000360 .

obo:WBPhenotype_0002134
    obo:IAO_0000115 "Animals are less successful than controls in evading predators during predator-prey interactions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002134" ;
    a owl:Class ;
    rdfs:label "predator escape defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002135 .

obo:WBPhenotype_0002135
    obo:IAO_0000115 "Predator-prey interactions differ from that observed in control interactions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002135" ;
    a owl:Class ;
    rdfs:label "organism predator response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 .

obo:WBPhenotype_0002136
    obo:IAO_0000115 "Animals are missing the anchor cell. In C. elegans the anchor cell is a key organizer of vulval patterning and morphogenesis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002136" ;
    a owl:Class ;
    rdfs:label "no anchor cell" ;
    rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0002174 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004522
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002137
    obo:IAO_0000115 "The rate of the process preceding formation of the peptide bond between the first two amino acids of a protein is reduced. This process includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.  Increase in free ribosomes (monosomes) are indicative of reduced translation initiation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002137" ;
    a owl:Class ;
    rdfs:label "reduced translation initiation" ;
    rdfs:subClassOf obo:WBPhenotype_0000121 .

obo:WBPhenotype_0002138
    obo:IAO_0000115 "Animals are altered in their capacity to survive a normally lethal temperature treatment as a consequence of pretreatment at an elevated but sublethal temperature." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002138" ;
    a owl:Class ;
    rdfs:label "acquired thermotolerance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000146 .

obo:WBPhenotype_0002139
    obo:IAO_0000115 "Any variation in the morphological appearance of the linker cell compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002139" ;
    a owl:Class ;
    rdfs:label "linker cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005062
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002140
    obo:IAO_0000115 "Males do not respond to small molecules or compounds that have been shown to attract control males. This phenotype is often measured by an increase in reversal frequency or time spent in a specified scoring region" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002140" ;
    a owl:Class ;
    rdfs:label "male attraction response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 .

obo:WBPhenotype_0002141
    obo:IAO_0000115 "Variations in the process of gaseous oxygen intake between an organism and its environment compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002141" ;
    a owl:Class ;
    rdfs:label "oxygen consumption variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001835 .

obo:WBPhenotype_0002142
    obo:IAO_0000115 "The activity, composition, or organization of the complexes of the electron transport chain, embedded in the inner mitochondrial membrane, differ from controls." ;
    oboInOwl:hasExactSynonym "MRC variant", "mitochondrial electron transport chain variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002142" ;
    a owl:Class ;
    rdfs:label "mitochondrial respiratory chain variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001282 .

obo:WBPhenotype_0002143
    obo:IAO_0000115 "The part of the respiratory chain that catalyzes the oxidation of succinate and connects the TCA cycle with the respiratory chain, differs in activity, composition, or organization, from that of controls." ;
    oboInOwl:hasExactSynonym "CO II variant", "Complex II variant", "Succinate dehydrogenase complex variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002143" ;
    a owl:Class ;
    rdfs:label "mitochondrial respiratory complex II variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002142 .

obo:WBPhenotype_0002144
    obo:IAO_0000115 "The protein complex located in the mitochondrial inner membrane that is the first entry point for electrons into the electron transport chain and catalyzes proton translocation coupled to the oxidation of NADH by ubiquinone, differs in activity, composition, or organization from that of controls." ;
    oboInOwl:hasExactSynonym "CO I variant", "Complex I variant", "NADH dehydrogenase complex variant", "Ubiquinone complex variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002144" ;
    a owl:Class ;
    rdfs:label "mitochondrial respiratory complex I variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002142 .

obo:WBPhenotype_0002145
    obo:IAO_0000115 "Animals are unable to produce or maintain short interfering RNA (siRNA) from double stranded RNA (dsRNA). siRNAs are required to initiate interference of gene expression." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002145" ;
    a owl:Class ;
    rdfs:label "siRNA processing defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000743, obo:WBPhenotype_0001776 .

obo:WBPhenotype_0002146
    obo:IAO_0000115 "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in the germline. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002146" ;
    a owl:Class ;
    rdfs:label "small RNA germline expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0002147
    obo:IAO_0000115 "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in somatic cells. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002147" ;
    a owl:Class ;
    rdfs:label "small RNA somatic expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0002148
    obo:IAO_0000115 "Animals show reduced susceptibility to gene silencing in somatic cells triggered by double stranded RNA (dsRNA), compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002148" ;
    a owl:Class ;
    rdfs:label "somatic RNAi resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001208 .

obo:WBPhenotype_0002149
    obo:IAO_0000115 "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of the small X-chromosome derived RNAs (X cluster) species of small RNA." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002149" ;
    a owl:Class ;
    rdfs:label "X cluster small RNA expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0002150
    obo:IAO_0000115 "RNAi silencing mechanisms triggered by exogenously introduced (foreign) dsRNA, do not work to the same degree as in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002150" ;
    a owl:Class ;
    rdfs:label "exo-RNAi response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 .

obo:WBPhenotype_0002151
    obo:IAO_0000115 "Animals exhibit variations in the extent to which polyadenylated mRNA transcripts become deadenylated" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002151" ;
    a owl:Class ;
    rdfs:label "mRNA deadenylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001827 .

obo:WBPhenotype_0002152
    obo:IAO_0000115 "Programmed cell death of germ cells caused by exposure to physical or chemical DNA-damaging agents does not occur to the same extent as it does in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002152" ;
    a owl:Class ;
    rdfs:label "mutagen induced apoptosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBPhenotype_0002153
    obo:IAO_0000115 "The production of silencing RNA from dsRNA is significantly deficient compared to controls. Deficiencies in this process can result in a defective RNAi response compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002153" ;
    a owl:Class ;
    rdfs:label "dsRNA processing defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000028 .

obo:WBPhenotype_0002154
    obo:IAO_0000115 "The extent of mRNA ribosome associations varies from controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002154" ;
    a owl:Class ;
    rdfs:label "polysome mRNA association variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000121, obo:WBPhenotype_0001371 .

obo:WBPhenotype_0002155
    obo:IAO_0000115 "The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002155" ;
    a owl:Class ;
    rdfs:label "pre miRNA processing defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000028, obo:WBPhenotype_0002528 .

obo:WBPhenotype_0002156
    obo:IAO_0000115 "Wild-type animals will exhibit an altered temperature preference based on food/temperature conditioning. Temperature learning variants do not exhibit altered responses to temperature after conditioning compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002156" ;
    a owl:Class ;
    rdfs:label "temperature learning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001780 .

obo:WBPhenotype_0002157
    obo:IAO_0000115 "The extent of translational repression varies from controls." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001909" ;
    oboInOwl:hasExactSynonym "translational repression variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002157" ;
    a owl:Class ;
    rdfs:label "translation repression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000121 .

obo:WBPhenotype_0002158
    obo:IAO_0000115 "The selective elimination of P granule components and subsequent aggregation of degraded components into PGL granules is disrupted." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002158" ;
    a owl:Class ;
    rdfs:label "P granule degradation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001301 .

obo:WBPhenotype_0002159
    obo:IAO_0000115 "Animals exhibit an increase in pathogen accumulation, persistent colonization, and luminal distension of the intestine." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002159" ;
    a owl:Class ;
    rdfs:label "increased pathogen accumulation" ;
    rdfs:subClassOf obo:WBPhenotype_0001819 .

obo:WBPhenotype_0002160
    obo:IAO_0000115 "The intracellular complex of proteins that participates in bidirectional transport of molecules (cargo) along axonemal microtubules is not made up of or does not maintain the proper number or ratio of components as found in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002160" ;
    a owl:Class ;
    rdfs:label "intraflagellar transport complex destabilized" ;
    rdfs:subClassOf obo:WBPhenotype_0002132 .

obo:WBPhenotype_0002161
    obo:IAO_0000115 "Animals exhibit variations from controls in the organization of chromatin, including in relation to associated complexes, that occur during the mitotic cell division cycle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002161" ;
    a owl:Class ;
    rdfs:label "mitotic chromatin remodeling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001348, obo:WBPhenotype_0001743 .

obo:WBPhenotype_0002162
    obo:IAO_0000115 "Cells exhibit mitotic spindles with more than two poles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "multipolar mitosis" ;
    oboInOwl:id "WBPhenotype:0002162" ;
    a owl:Class ;
    rdfs:label "multipolar mitotic spindle" ;
    rdfs:subClassOf obo:WBPhenotype_0001215, obo:WBPhenotype_0001743 .

obo:WBPhenotype_0002163
    obo:IAO_0000115 "Animals exhibit a decreased rate of oxygen utilization compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002163" ;
    a owl:Class ;
    rdfs:label "oxygen consumption decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002141 .

obo:WBPhenotype_0002164
    obo:IAO_0000115 "Animals exhibit variations in their defense responses that are mediated by germline encoded components that directly recognize components of potential pathogens." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002164" ;
    a owl:Class ;
    rdfs:label "innate immune response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001012 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0045087
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002165
    obo:IAO_0000115 "The extent or other quality of the excitatory postsynaptic potential (EPSP) induced by in vitro stimuli differs from that of controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002165" ;
    a owl:Class ;
    rdfs:label "muscle excitability variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001735, obo:WBPhenotype_0002014 .

obo:WBPhenotype_0002166
    obo:IAO_0000115 "The difference in electrical potential between the interior and the exterior of the muscle cell either in the resting state or during evoked stimulation differs from controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002166" ;
    a owl:Class ;
    rdfs:label "muscle membrane potential variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000990, obo:WBPhenotype_0001965 .

obo:WBPhenotype_0002167
    obo:IAO_0000115 "The amount of histone methylation, for example as measured by the amount of H3K4me2, increases over successive generations" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "generational accumulation of histone methylation", "progressive accumulation of histone methylation", "transgenerational epigenetic accumulation of histone methylation" ;
    oboInOwl:id "WBPhenotype:0002167" ;
    a owl:Class ;
    rdfs:label "transgenerational accumulation of histone methylation" ;
    rdfs:subClassOf obo:WBPhenotype_0002078 .

obo:WBPhenotype_0002168
    obo:IAO_0000115 "Animals exhibit a decline in fertility over generations. This is often assessed by counting laid eggs over successive generations." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "generational loss of fertility", "progressive loss of fertility", "transgenerational epigenetic loss of fertility" ;
    oboInOwl:id "WBPhenotype:0002168" ;
    a owl:Class ;
    rdfs:label "transgenerational loss of fertility" ;
    rdfs:subClassOf obo:WBPhenotype_0000145 .

obo:WBPhenotype_0002169
    obo:IAO_0000115 "Animals stop producing progeny significantly before the time reproduction stops in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002169" ;
    a owl:Class ;
    rdfs:label "reproductive longevity shortened" ;
    rdfs:subClassOf obo:WBPhenotype_0001739 .

obo:WBPhenotype_0002170
    obo:IAO_0000115 "Any variation in the series of molecular signals in which a cell or tissue uses calcium ions to convert a signal into a response, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002170" ;
    a owl:Class ;
    rdfs:label "calcium mediated signaling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0002171
    obo:IAO_0000115 "Animals exhibit variations in the characteristic movement towards typically attractive alkaline pH (pH higher than 7) compared to control. However animals tend to avoid very high pH levels (pH11).  pH is a measure of the acidity or basicity of an aqueous solution. In C. elegans animals chemotax toward higher alkaline pH." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "alkaline pH sensing variant", "alkalinity sensing variant" ;
    oboInOwl:id "WBPhenotype:0002171" ;
    a owl:Class ;
    rdfs:label "alkaline pH chemotaxis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001047 .

obo:WBPhenotype_0002172
    obo:IAO_0000115 "Infected animals exhibit variations in the process of releasing pathogens back into the environment, compared to control." ;
    oboInOwl:hasNarrowSynonym "spore shedding variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002172" ;
    a owl:Class ;
    rdfs:label "pathogen release variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001012 .

obo:WBPhenotype_0002173
    obo:IAO_0000115 "Animals exhibit variations in the number of cells that make up the organism compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002173" ;
    a owl:Class ;
    rdfs:label "cell number variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000531 .

obo:WBPhenotype_0002174
    obo:IAO_0000115 "The number of cells in the organism is reduced compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002174" ;
    a owl:Class ;
    rdfs:label "cell number decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002173 .

obo:WBPhenotype_0002175
    obo:IAO_0000115 "The number of cells in the organism is increased compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002175" ;
    a owl:Class ;
    rdfs:label "cell number increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002173 .

obo:WBPhenotype_0002176
    obo:IAO_0000115 "Animals exhibit variations in the structure, organization or placement of the population of the lateral, alae-producing epithelial cells (seam cells), compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002176" ;
    a owl:Class ;
    rdfs:label "seam cell morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000899 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005753
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002177
    obo:IAO_0000115 "Any variation in the components that make up the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002177" ;
    a owl:Class ;
    rdfs:label "plasma membrane composition variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0002178
    obo:IAO_0000115 "Any variation in the components that make up either of the two leaflets of the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002178" ;
    a owl:Class ;
    rdfs:label "plasma membrane leaflet composition variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002177 .

obo:WBPhenotype_0002179
    obo:IAO_0000115 "Animals do not arrest mitotic germ cell division, as control animals, when treated with X-ray radiation." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002179" ;
    a owl:Class ;
    rdfs:label "X ray induced mitotic germ cell arrest defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001324 .

obo:WBPhenotype_0002180
    obo:IAO_0000115 "Animals exhibit variations in the process by which cells having undergone programmed cell death are shed or extruded into the extracellular environment." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002180" ;
    a owl:Class ;
    rdfs:label "apoptotic cell shedding variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBPhenotype_0002181
    obo:IAO_0000115 "Animals produce an excess number of excretory cells compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002181" ;
    a owl:Class ;
    rdfs:label "extra excretory cells" ;
    rdfs:subClassOf obo:WBPhenotype_0000621, obo:WBPhenotype_0002175 .

obo:WBPhenotype_0002182
    obo:IAO_0000115 "Animals exhibit variations in endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002182" ;
    a owl:Class ;
    rdfs:label "reactive oxygen species homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0002183
    obo:IAO_0000115 "Animals exhibit variations in levels of DNA damage caused by oxidative stress." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002183" ;
    a owl:Class ;
    rdfs:label "oxidative DNA damage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000732 .

obo:WBPhenotype_0002184
    obo:IAO_0000115 "Any variation in the amount of cells undergoing apoptosis in organism as a result of deprivation of nourishment, compared to control. In C. elegans, starvation normally causes increased apoptosis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002184" ;
    a owl:Class ;
    rdfs:label "starvation induced apoptosis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000147, obo:WBPhenotype_0000730 .

obo:WBPhenotype_0002185
    obo:IAO_0000115 "Animals develop endodermal cells/tissue from precursor cells that do not normally produce endodermal cells/tissue." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002185" ;
    a owl:Class ;
    rdfs:label "cell fate transformation to endoderm" ;
    rdfs:subClassOf obo:WBPhenotype_0000414 .

obo:WBPhenotype_0002186
    obo:IAO_0000115 "Animals develop pharyngeal muscles from precursor cells that do not normally produce pharyngeal muscles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002186" ;
    a owl:Class ;
    rdfs:label "cell fate transformation to pharyngeal muscle" ;
    rdfs:subClassOf obo:WBPhenotype_0000414 .

obo:WBPhenotype_0002187
    obo:IAO_0000115 "Animals develop body wall muscle from precursor cells that do not normally produce body wall muscle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002187" ;
    a owl:Class ;
    rdfs:label "cell fate transformation to body wall muscle" ;
    rdfs:subClassOf obo:WBPhenotype_0000414 .

obo:WBPhenotype_0002188
    obo:IAO_0000115 "Any variation in the progression of the components of the male gonad that are separate from the germline proper over time, from its formation to its mature structure compared to control.  In C. elegans, the male somatic gonad consists of three tissues: distal tip cells (DTCs), the seminal vesicle, and the vas deferens (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002188" ;
    a owl:Class ;
    rdfs:label "male somatic gonad development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0001675 .

obo:WBPhenotype_0002189
    obo:IAO_0000115 "Animals produce an excess number of linker cells compared to controls." ;
    oboInOwl:hasExactSynonym "excess linker cells" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002189" ;
    a owl:Class ;
    rdfs:label "extra linker cells" ;
    rdfs:subClassOf obo:WBPhenotype_0001675, obo:WBPhenotype_0002175 .

obo:WBPhenotype_0002190
    obo:IAO_0000115 "The population of hypodermal cells is reduced compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002190" ;
    a owl:Class ;
    rdfs:label "fewer hypodermal cells" ;
    rdfs:subClassOf obo:WBPhenotype_0002174 .

obo:WBPhenotype_0002191
    obo:IAO_0000115 "Animals produce a reduced number of sex myoblasts compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002191" ;
    a owl:Class ;
    rdfs:label "fewer sex myoblasts" ;
    rdfs:subClassOf obo:WBPhenotype_0002174 .

obo:WBPhenotype_0002192
    obo:IAO_0000115 "Animals produce an excess number of sex myoblasts compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002192" ;
    a owl:Class ;
    rdfs:label "extra sex myoblasts" ;
    rdfs:subClassOf obo:WBPhenotype_0002175 .

obo:WBPhenotype_0002193
    obo:IAO_0000115 "The orientation of the progeny of P7.p mimic those of P5.p and face towards the posterior of the worm, a phenotype referred to as posterior-reversed vulval lineage (P-Rvl)." ;
    oboInOwl:hasBroadSynonym "P-Rvl" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002193" ;
    a owl:Class ;
    rdfs:label "posterior reversed vulval lineage" ;
    rdfs:subClassOf obo:WBPhenotype_0000220, obo:WBPhenotype_0000239 .

obo:WBPhenotype_0002194
    obo:IAO_0000115 "Animals do not differ in size when grown on different food sources to the same extent as that measured for control animals. For example, in C. elegans, wild type worms are 1.65 times larger when grown on HB101 compared to those grown on OP50." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002194" ;
    a owl:Class ;
    rdfs:label "food dependent body size variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002195 .

obo:WBPhenotype_0002195
    obo:IAO_0000115 "Animals exhibit variations in growth rate or the outcome of growth in response to food compared to control. In C. elegans, animals exhibit an increase or decrease in growth rate depending on the type of bacteria they are fed." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002195" ;
    a owl:Class ;
    rdfs:label "food dependent growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001072 .

obo:WBPhenotype_0002196
    obo:IAO_0000115 "The driving force of the outward flow of ions does not exceed the inward flow for the opposite driving force or is otherwise altered when compared to that measured for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002196" ;
    a owl:Class ;
    rdfs:label "outward rectifying current variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002197 .

obo:WBPhenotype_0002197
    obo:IAO_0000115 "Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded is altered from that observed for controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002197" ;
    a owl:Class ;
    rdfs:label "voltage gated channel activity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001315 .

obo:WBPhenotype_0002198
    obo:IAO_0000115 "The proper localization and assembly of components at the junction of a neuron with a muscle cell varies from that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002198" ;
    a owl:Class ;
    rdfs:label "neuromuscular junction organization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000625 .

obo:WBPhenotype_0002199
    obo:IAO_0000115 "The degree of stimulus-evoked calcium concentration changes differs from that of controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002199" ;
    a owl:Class ;
    rdfs:label "neuron calcium transient levels variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 .

obo:WBPhenotype_0002200
    obo:IAO_0000115 "Variations in the progression of the muscles of the adult hermaphrodite oviduct over time from their initial formation to their mature structure compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002200" ;
    a owl:Class ;
    rdfs:label "oviduct muscle defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000282 .

obo:WBPhenotype_0002201
    obo:IAO_0000115 "Dying animals cells exhibit defects in the fragmentation of chromosomal DNA into oligonucleosomal-length fragments compared to control animals. This process can be monitored by the quantity and quality of TUNEL (TdT-mediated dUTP nick end labeling)-positive nuclei." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002201" ;
    a owl:Class ;
    rdfs:label "apoptotic DNA degradation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBPhenotype_0002202
    obo:IAO_0000115 "Embryos exhibit defects in the extension of pharyngeal cells toward the buccal opening during embryogenesis compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002202" ;
    a owl:Class ;
    rdfs:label "pharynx extension defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001748 .

obo:WBPhenotype_0002203
    obo:IAO_0000115 "Corpses resulting from programmed cell death appear different in size or shape from those of corpses in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002203" ;
    a owl:Class ;
    rdfs:label "corpse morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBPhenotype_0002204
    obo:IAO_0000115 "Animals exhibit defects in the muscle contractions of the anterior region of corpus, the area responsible for allowing food to enter the corpus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002204" ;
    a owl:Class ;
    rdfs:label "procorpus contraction defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000327 .

obo:WBPhenotype_0002205
    obo:IAO_0000115 "Animals exhibit negative effects on growth, development, or metabolism when exposed to a galactose-rich diet, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002205" ;
    a owl:Class ;
    rdfs:label "hypersensitive to galactose" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_28260
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002206
    obo:IAO_0000115 "Animals process dietary galactose differently than control animals, these differences can result in increased and or decreased levels of intermediary galactose metabolites." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002206" ;
    a owl:Class ;
    rdfs:label "galactose metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0002207
    obo:IAO_0000115 "Animals are missing one or both gonad arms, the normally U-shaped projections of the gonad that extend into the anterior or posterior of the animal and bends back towards the center of the animal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002207" ;
    a owl:Class ;
    rdfs:label "missing gonad arms" ;
    rdfs:subClassOf obo:WBPhenotype_0000399 .

obo:WBPhenotype_0002208
    obo:IAO_0000115 "The expression of a protein, as determined by antibody staining, varied from controls with respect to timing such that the protein was observed to be expressed at earlier timepoints or later timepoints than controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002208" ;
    a owl:Class ;
    rdfs:label "antibody temporal expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000424 .

obo:WBPhenotype_0002209
    obo:IAO_0000115 "Any variation in the development of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002209" ;
    a owl:Class ;
    rdfs:label "hook development variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000624, obo:WBPhenotype_0001297 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0032502
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:RO_0002295 ;
                                owl:someValuesFrom obo:WBbt_0008425
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002210
    obo:IAO_0000115 "Animals exhibit an extra number of the finger-like sensory sensilla that project from the tail and embed in the male fan." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002210" ;
    a owl:Class ;
    rdfs:label "extra rays" ;
    rdfs:subClassOf obo:WBPhenotype_0000199 .

obo:WBPhenotype_0002211
    obo:IAO_0000115 "Animals exhibit defects in dye-filling of the neuronal cells of the phasmid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002211" ;
    a owl:Class ;
    rdfs:label "phasmid neuron dye filling defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000257, obo:WBPhenotype_0002535 .

obo:WBPhenotype_0002212
    obo:IAO_0000115 "Animals exhibit defects in dye-filling of the neuronal cells of the amphid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002212" ;
    a owl:Class ;
    rdfs:label "amphid neuron dye filling defect" ;
    rdfs:subClassOf obo:WBPhenotype_0000256, obo:WBPhenotype_0002535 .

obo:WBPhenotype_0002213
    obo:IAO_0000115 "Any variation that results in a decrease in the catalytic phosphorylation activity of a kinase enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component). Kinases are enzymes capable of phosphorylating their respective substrates." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002213" ;
    a owl:Class ;
    rdfs:label "kinase activity reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000124 .

obo:WBPhenotype_0002214
    obo:IAO_0000115 "Animals contain an excess number of pharyngeal muscle cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002214" ;
    a owl:Class ;
    rdfs:label "extra pharyngeal muscle cells" ;
    rdfs:subClassOf obo:WBPhenotype_0001635 .

obo:WBPhenotype_0002215
    obo:IAO_0000115 "Any variation that results in a fewer than control number of body wall muscle cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002215" ;
    a owl:Class ;
    rdfs:label "fewer body wall muscles" ;
    rdfs:subClassOf obo:WBPhenotype_0001597 .

obo:WBPhenotype_0002216
    obo:IAO_0000115 "Any variation in the cellular or subcellular distribution of a gene product, as detected by antibody staining, compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002216" ;
    a owl:Class ;
    rdfs:label "pattern antibody staining variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000424 .

obo:WBPhenotype_0002217
    obo:IAO_0000115 "Animals respond to antimony at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002217" ;
    a owl:Class ;
    rdfs:label "antimony hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001918 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_30513
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002218
    obo:IAO_0000115 "Animals respond to arsenite at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002218" ;
    a owl:Class ;
    rdfs:label "arsenite hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001918 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_22633
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002219
    obo:IAO_0000115 "Animals respond to fluoranthene at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002219" ;
    a owl:Class ;
    rdfs:label "fluoranthene hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0001918 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_33083
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002220
    obo:IAO_0000115 "Animals respond to antimonite at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002220" ;
    a owl:Class ;
    rdfs:label "antimonite hypersensitivity" ;
    rdfs:subClassOf obo:WBPhenotype_0002217 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_30297
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002221
    obo:IAO_0000115 "The pharynx contains cavities, possibly indicative of inappropriate cell death." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002221" ;
    a owl:Class ;
    rdfs:label "pharyngeal vacuole" ;
    rdfs:subClassOf obo:WBPhenotype_0001363, obo:WBPhenotype_0002615 .

obo:WBPhenotype_0002222
    obo:IAO_0000115 "The uterus contains cavities, possibly indicative of inappropriate cell death." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002222" ;
    a owl:Class ;
    rdfs:label "uterus vacuole" ;
    rdfs:subClassOf obo:WBPhenotype_0001395 .

obo:WBPhenotype_0002223
    obo:IAO_0000115 "Animals respond at a faster rate or to lower concentrations of manganese that that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002223" ;
    a owl:Class ;
    rdfs:label "manganese hypersensitivity" ;
    rdfs:subClassOf obo:WBPhenotype_0001863 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_18291
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002224
    obo:IAO_0000115 "Animals respond to mercury at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002224" ;
    a owl:Class ;
    rdfs:label "mercury hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_25195
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002225
    obo:IAO_0000115 "Animals respond to lead at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002225" ;
    a owl:Class ;
    rdfs:label "lead hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0002227 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_25016
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002226
    obo:IAO_0000115 "Animals respond to cobalt at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002226" ;
    a owl:Class ;
    rdfs:label "cobalt hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_27638
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002227
    obo:IAO_0000115 "Animals exhibit variations in their response to lead compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002227" ;
    a owl:Class ;
    rdfs:label "lead response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010288
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002228
    obo:IAO_0000115 "Animals exhibit variations in their response to aluminum compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002228" ;
    a owl:Class ;
    rdfs:label "aluminum response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010044
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002229
    obo:IAO_0000115 "Animals exhibit variations in their response to chromium compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002229" ;
    a owl:Class ;
    rdfs:label "chromium response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 .

obo:WBPhenotype_0002230
    obo:IAO_0000115 "Animals exhibited higher amounts of internal metal concentrations compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002230" ;
    a owl:Class ;
    rdfs:label "metal accumulation increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002029 .

obo:WBPhenotype_0002231
    obo:IAO_0000115 "Oxidative stress induced by manganese differs from that of control worms." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002231" ;
    a owl:Class ;
    rdfs:label "manganese induced oxidative stress response" ;
    rdfs:subClassOf obo:WBPhenotype_0001620 .

obo:WBPhenotype_0002232
    obo:IAO_0000115 "The polarity reversal process by which synaptic components are removed from one side of the synapse and then reformed on the opposite cell does not occur or occurs in a different manner than in controls. In C. elegans, at the end of the L1 stage, the DD neurons undergo a complete polarity reversal such that the ventral synapses disappear and new synapses are formed on opposing dorsal body muscles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002232" ;
    a owl:Class ;
    rdfs:label "synaptic remodeling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000625 .

obo:WBPhenotype_0002233
    obo:IAO_0000115 "The swimming behavior of animals are influenced or modulate by the osmolarity of the swimming buffer. The swimming of wild-type C. elegans animals are not affected by the osmolarity of the swimming liquid." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002233" ;
    a owl:Class ;
    rdfs:label "osmolarity modulated swimming variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000876 .

obo:WBPhenotype_0002234
    obo:IAO_0000115 "Animals contain excess acidified intracellular compartments. These compartments are positive for indicators such as Acridine Orange as well as LysoTracker Red, in a lysosome-like manner." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002234" ;
    a owl:Class ;
    rdfs:label "increased acidified compartments" ;
    rdfs:subClassOf obo:WBPhenotype_0001393 .

obo:WBPhenotype_0002235
    obo:IAO_0000115 "Animals are unable to grow on media depleted of phosphate." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002235" ;
    a owl:Class ;
    rdfs:label "growth defective on low phosphate media" ;
    rdfs:subClassOf obo:WBPhenotype_0000576 .

obo:WBPhenotype_0002236
    obo:IAO_0000115 "The degradation of endocytosed and intracellular material does not occur to the same extent as it does in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002236" ;
    a owl:Class ;
    rdfs:label "endo lysosomal degradation pathway defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000585 .

obo:WBPhenotype_0002237
    obo:IAO_0000115 "Animals exhibit disruptions in tubular or tubulo-vesicular structures that function in endocytic transport from early to recycling endosomes." ;
    oboInOwl:hasExactSynonym "ERC organization and biogenesis defective" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002237" ;
    a owl:Class ;
    rdfs:label "endocytic recycling compartment organization and biogenesis defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 .

obo:WBPhenotype_0002238
    obo:IAO_0000115 "Animals exhibit increased endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002238" ;
    a owl:Class ;
    rdfs:label "increased levels of reactive oxygen species" ;
    rdfs:subClassOf obo:WBPhenotype_0002182 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_26523
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002239
    obo:IAO_0000115 "Animals exhibit reduced endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002239" ;
    a owl:Class ;
    rdfs:label "reduced levels of reactive oxygen species" ;
    rdfs:subClassOf obo:WBPhenotype_0002182 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_26523
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002240
    obo:IAO_0000115 "Any variation in the morphology of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002240" ;
    a owl:Class ;
    rdfs:label "gut granule morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000902 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0044840
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002241
    obo:IAO_0000115 "Animals consume less food than control animals" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002241" ;
    a owl:Class ;
    rdfs:label "feeding reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000659 .

obo:WBPhenotype_0002242
    obo:IAO_0000115 "Animals exhibit detrimental responses to iron deficiency more readily than control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002242" ;
    a owl:Class ;
    rdfs:label "hypersensitive to iron deficiency" ;
    rdfs:subClassOf obo:WBPhenotype_0002046 .

obo:WBPhenotype_0002243
    obo:IAO_0000115 "Animals do not produce the same amount of functional phytochelatins as measured in control worms. Phytochelatins are any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002243" ;
    a owl:Class ;
    rdfs:label "phytochelatin synthesis deficient" ;
    rdfs:subClassOf obo:WBPhenotype_0001696 .

obo:WBPhenotype_0002244
    obo:IAO_0000115 "Animals respond to arsenic at a lower concentration or at a shorter exposure time compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002244" ;
    a owl:Class ;
    rdfs:label "arsenic hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_27563
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002245
    obo:IAO_0000115 "Animals exhibit reduced levels of endogenous zinc compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002245" ;
    a owl:Class ;
    rdfs:label "endogenous zinc levels reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0001849 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_27363
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002246
    obo:IAO_0000115 "Animals exhibit increased levels of endogenous zinc compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002246" ;
    a owl:Class ;
    rdfs:label "endogenous zinc levels increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001849 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_27363
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002247
    obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of copper ions within an organism compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002247" ;
    a owl:Class ;
    rdfs:label "copper homeostasis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002029 .

obo:WBPhenotype_0002248
    obo:IAO_0000115 "Animals exhibit detrimental responses to zinc deficiency more readily than control animals" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002248" ;
    a owl:Class ;
    rdfs:label "hypersensitive to zinc deficiency" ;
    rdfs:subClassOf obo:WBPhenotype_0001849 .

obo:WBPhenotype_0002249
    obo:IAO_0000115 "Protein oxidation levels, as measured by carbonylated protein levels for example, are reduced compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002249" ;
    a owl:Class ;
    rdfs:label "reduced protein oxidation levels" ;
    rdfs:subClassOf obo:WBPhenotype_0000068 .

obo:WBPhenotype_0002250
    obo:IAO_0000115 "Animals respond to silver at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002250" ;
    a owl:Class ;
    rdfs:label "silver hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_30512
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002251
    obo:IAO_0000115 "Animals respond to silver nanoparticles (AgNPs) at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002251" ;
    a owl:Class ;
    rdfs:label "silver nanoparticle hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0002250 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_50826
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002252
    obo:IAO_0000115 "Animals are more prone to infection by virus compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002252" ;
    a owl:Class ;
    rdfs:label "increased susceptibility to viral infection" ;
    rdfs:subClassOf obo:WBPhenotype_0001013 .

obo:WBPhenotype_0002253
    obo:IAO_0000115 "Animals exhibit lowered levels of any or all of the clades of 22G RNA molecules, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002253" ;
    a owl:Class ;
    rdfs:label "22G RNA expression reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000113 .

obo:WBPhenotype_0002254
    obo:IAO_0000115 "Three-prime (3') uridylation of mRNA targeted for silencing does not occur at the same rate or extent of targeted mRNA in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002254" ;
    a owl:Class ;
    rdfs:label "three prime target RNA uridylation reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000028 .

obo:WBPhenotype_0002255
    obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of amino acids within the organism or cell compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002255" ;
    a owl:Class ;
    rdfs:label "amino acid metabolism variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000463 .

obo:WBPhenotype_0002256
    obo:IAO_0000115 "Animals exhibit variations in their response to selenium compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002256" ;
    a owl:Class ;
    rdfs:label "selenium response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0010269
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002257
    obo:IAO_0000115 "Animals respond to iron at a lower concentration or a shorter exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002257" ;
    a owl:Class ;
    rdfs:label "iron hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001651
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_18248
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002258
    obo:IAO_0000115 "Animals fail to exhibit toxicity to the concentration of nickel that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to nickel include delayed development or lethality." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002258" ;
    a owl:Class ;
    rdfs:label "nickel toxicity resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000591 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_28112
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002259
    obo:IAO_0000115 "The number of terminal regions of a neuron's dendrite is less that that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002259" ;
    a owl:Class ;
    rdfs:label "dendritic termini number reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000882 .

obo:WBPhenotype_0002260
    obo:IAO_0000115 "Ooctyes and or sperm appear vacuolated and degenerated compared to gametes in control animals. This degeneration is not due to normal programmed cell death." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "necrotic gamete degeneration increased" ;
    oboInOwl:id "WBPhenotype:0002260" ;
    a owl:Class ;
    rdfs:label "gamete necrotic death increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001397 .

obo:WBPhenotype_0002261
    obo:IAO_0000115 "An effective connection between reciprocal target neurons is not established properly." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002261" ;
    a owl:Class ;
    rdfs:label "neurite connectivity defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000623 .

obo:WBPhenotype_0002262
    obo:IAO_0000115 "Animals display variations in the distribution of the constituents of the postsynaptic side of the active zone, compared to control animals, that are required for receiving signals from the presynaptic side." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002262" ;
    a owl:Class ;
    rdfs:label "postsynaptic component localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001685 .

obo:WBPhenotype_0002263
    obo:IAO_0000115 "Any increase in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002263" ;
    a owl:Class ;
    rdfs:label "mitochondrial membrane potential increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001282 .

obo:WBPhenotype_0002264
    obo:IAO_0000115 "Animals exhibit an increase in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002264" ;
    a owl:Class ;
    rdfs:label "ATP levels increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001574 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_15422
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002265
    obo:IAO_0000115 "Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002265" ;
    a owl:Class ;
    rdfs:label "lysosome-related organelle biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 .

obo:WBPhenotype_0002266
    obo:IAO_0000115 "Animals exhibit variations in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002266" ;
    a owl:Class ;
    rdfs:label "mitochondrial content variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 .

obo:WBPhenotype_0002267
    obo:IAO_0000115 "Animals exhibit increases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002267" ;
    a owl:Class ;
    rdfs:label "mitochondrial content increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002266 .

obo:WBPhenotype_0002268
    obo:IAO_0000115 "Animals exhibit decreases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002268" ;
    a owl:Class ;
    rdfs:label "mitochondrial content decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002266 .

obo:WBPhenotype_0002269
    obo:IAO_0000115 "Animals exhibit an increased rate of oxygen utilization compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002269" ;
    a owl:Class ;
    rdfs:label "oxygen consumption increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002141 .

obo:WBPhenotype_0002270
    obo:IAO_0000115 "Animals exhibit a decrease in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002270" ;
    a owl:Class ;
    rdfs:label "metabolite content decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000463 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_25212
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002271
    obo:IAO_0000115 "Animals exhibit variations in the rate at which food is absorbed by the intestine, as determined by a time-course recording of fat staining (by C1-BODIPY-C12, for example) normalized to controls" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002271" ;
    a owl:Class ;
    rdfs:label "food absorption rate variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000659 .

obo:WBPhenotype_0002272
    obo:IAO_0000115 "Animals exhibit variations in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002272" ;
    a owl:Class ;
    rdfs:label "protein carbonylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 .

obo:WBPhenotype_0002273
    obo:IAO_0000115 "Animals exhibit enhanced negative effects on growth, health, development or metabolism, in response to dietary sugar-rich diets, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002273" ;
    a owl:Class ;
    rdfs:label "dietary sugar response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002525 .

obo:WBPhenotype_0002274
    obo:IAO_0000115 "Males receive copulatory plugs from other males, deposited elsewhere on their bodies, in the absence of any orifice. This typically involves penetration of the depositing male's spicules directly through the cuticle of the recipient male." ;
    oboInOwl:hasBroadSynonym "Plob" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002274" ;
    a owl:Class ;
    rdfs:label "plugged on body" ;
    rdfs:subClassOf obo:WBPhenotype_0001728 .

obo:WBPhenotype_0002275
    obo:IAO_0000115 "Males receive copulatory plugs from other males, deposited on their excretory pores. This phenotype is polymorphic among C. elegans strains and also in C. briggsae." ;
    oboInOwl:hasBroadSynonym "Pleb" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Plep" ;
    oboInOwl:id "WBPhenotype:0002275" ;
    a owl:Class ;
    rdfs:label "plugged excretory pore" ;
    rdfs:subClassOf obo:WBPhenotype_0001728 .

obo:WBPhenotype_0002276
    obo:IAO_0000115 "The life span of dauer-staged animals is shorter than that observed in control dauer animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002276" ;
    a owl:Class ;
    rdfs:label "dauer lifespan shortened" ;
    rdfs:subClassOf obo:WBPhenotype_0001540 .

obo:WBPhenotype_0002277
    obo:IAO_0000115 "The life span of dauer-staged animals is longer than that observed in control dauer animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002277" ;
    a owl:Class ;
    rdfs:label "dauer lifespan extended" ;
    rdfs:subClassOf obo:WBPhenotype_0001540 .

obo:WBPhenotype_0002278
    obo:IAO_0000115 "Animals do not develop acute functional tolerance to alcohol after a short exposure, unlike that observed in control animals" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "ATF" ;
    oboInOwl:id "WBPhenotype:0002278" ;
    a owl:Class ;
    rdfs:label "acute functional tolerance to alcohol defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000555 .

obo:WBPhenotype_0002279
    obo:IAO_0000115 "Animals exhibit a decrease in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "lipid body size decreased" ;
    oboInOwl:id "WBPhenotype:0002279" ;
    a owl:Class ;
    rdfs:label "fat associated body size decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0001901 .

obo:WBPhenotype_0002280
    obo:IAO_0000115 "Animals exhibit resistance to osmotic stress compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002280" ;
    a owl:Class ;
    rdfs:label "organism osmotic stress resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000876 .

obo:WBPhenotype_0002281
    obo:IAO_0000115 "Animals exhibit hypersensitivty to osmotic stress compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002281" ;
    a owl:Class ;
    rdfs:label "organism osmotic stress hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000876 .

obo:WBPhenotype_0002282
    obo:IAO_0000115 "Animals exhibit increased levels of the process by which their cells digest parts of their own cytoplasm, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002282" ;
    a owl:Class ;
    rdfs:label "autophagy increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000736 .

obo:WBPhenotype_0002283
    obo:IAO_0000115 "Animals exhibit reduced levels of the process by which their cells digest parts of their own cytoplasm, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002283" ;
    a owl:Class ;
    rdfs:label "autophagy reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000736 .

obo:WBPhenotype_0002284
    obo:IAO_0000115 "Any variation in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002284" ;
    a owl:Class ;
    rdfs:label "head bend angle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001265 .

obo:WBPhenotype_0002285
    obo:IAO_0000115 "Animals exhibit a decrease in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002285" ;
    a owl:Class ;
    rdfs:label "head bend angle decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002284 .

obo:WBPhenotype_0002286
    obo:IAO_0000115 "Animals exhibit an increase in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002286" ;
    a owl:Class ;
    rdfs:label "head bend angle increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002284 .

obo:WBPhenotype_0002287
    obo:IAO_0000115 "The most posterior portion of the animal exhibits variations in its movement compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002287" ;
    a owl:Class ;
    rdfs:label "tail movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001699 .

obo:WBPhenotype_0002288
    obo:IAO_0000115 "Any variation in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002288" ;
    a owl:Class ;
    rdfs:label "tail bend angle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002287 .

obo:WBPhenotype_0002289
    obo:IAO_0000115 "Animals exhibit an increase in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002289" ;
    a owl:Class ;
    rdfs:label "tail bend angle increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002288 .

obo:WBPhenotype_0002290
    obo:IAO_0000115 "Animals exhibit a decrease in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002290" ;
    a owl:Class ;
    rdfs:label "tail bend angle decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002288 .

obo:WBPhenotype_0002291
    obo:IAO_0000115 "Animals exhibit variations in body posture with regard to the extent of displacement measured from the mean position to an extreme position compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002291" ;
    a owl:Class ;
    rdfs:label "body posture amplitude variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000001 .

obo:WBPhenotype_0002292
    obo:IAO_0000115 "Animals exhibit variations in body posture caused by a decrease in the extent of displacement measured from the mean position to an extreme position compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002292" ;
    a owl:Class ;
    rdfs:label "body posture amplitude decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002291 .

obo:WBPhenotype_0002293
    obo:IAO_0000115 "Animals exhibit variations in body posture caused by an increase in the extent of displacement measured from the mean position to an extreme position compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002293" ;
    a owl:Class ;
    rdfs:label "body posture amplitude increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002291 .

obo:WBPhenotype_0002294
    obo:IAO_0000115 "Animals exhibit variations in body posture with regard to the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002294" ;
    a owl:Class ;
    rdfs:label "body posture wavelength variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000001 .

obo:WBPhenotype_0002295
    obo:IAO_0000115 "Animals exhibit variations in body posture caused by a decrease in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002295" ;
    a owl:Class ;
    rdfs:label "body posture wavelength decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002294 .

obo:WBPhenotype_0002296
    obo:IAO_0000115 "Animals exhibit variations in body posture caused by an increase in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002296" ;
    a owl:Class ;
    rdfs:label "body posture wavelength increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002294 .

obo:WBPhenotype_0002297
    obo:IAO_0000115 "Animals exhibit variations in the occurrence of a coil-like body posture compared to control animals. This includes the amount of time spent in a coil, the frequency with which coils form and the inappropriate formation of a coil, for example when attempting to locomote." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002297" ;
    a owl:Class ;
    rdfs:label "coiling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000001 .

obo:WBPhenotype_0002298
    obo:IAO_0000115 "Animals exhibit variations in the amount of time spent with its body posture in a coil or the frequency with which they form coils compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002298" ;
    a owl:Class ;
    rdfs:label "coiling frequency variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002297 .

obo:WBPhenotype_0002299
    obo:IAO_0000115 "Animals spend less time with their body posture in a coil or they decrease the frequency with which they form coils compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002299" ;
    a owl:Class ;
    rdfs:label "coiling frequency decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002298 .

obo:WBPhenotype_0002300
    obo:IAO_0000115 "Animals spend more time with their body posture in a coil or they increase the frequency with which they form coils compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002300" ;
    a owl:Class ;
    rdfs:label "coiling frequency increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002298 .

obo:WBPhenotype_0002301
    obo:IAO_0000115 "The extreme anterior of the animal exhibits variations in its movement compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002301" ;
    a owl:Class ;
    rdfs:label "nose movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000662, obo:WBPhenotype_0001699 .

obo:WBPhenotype_0002302
    obo:IAO_0000115 "Animals exhibit a decrease in the movement of the extreme anterior portion of the body to a new location compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002302" ;
    a owl:Class ;
    rdfs:label "nose movement decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002301 .

obo:WBPhenotype_0002303
    obo:IAO_0000115 "Animals exhibit an increase in the movement of the extreme anterior portion of the body to a new location compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002303" ;
    a owl:Class ;
    rdfs:label "nose movement increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002301 .

obo:WBPhenotype_0002304
    obo:IAO_0000115 "Animals exhibit a decrease in the movement of the most anterior portion of the body to a new location compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002304" ;
    a owl:Class ;
    rdfs:label "head movement decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000595, obo:WBPhenotype_0001265 .

obo:WBPhenotype_0002305
    obo:IAO_0000115 "Animals exhibit an increase in the movement of the most anterior portion of the body to a new location compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002305" ;
    a owl:Class ;
    rdfs:label "head movement increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000595, obo:WBPhenotype_0001265 .

obo:WBPhenotype_0002306
    obo:IAO_0000115 "Animals exhibit a decrease in the movement of the most posterior portion of the body to a new location compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002306" ;
    a owl:Class ;
    rdfs:label "tail movement decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000597, obo:WBPhenotype_0002287 .

obo:WBPhenotype_0002307
    obo:IAO_0000115 "Animals exhibit an increase in the movement of the most posterior portion of the body to a new location compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002307" ;
    a owl:Class ;
    rdfs:label "tail movement increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000597, obo:WBPhenotype_0002287 .

obo:WBPhenotype_0002308
    obo:IAO_0000115 "Animals exhibit variations in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002308" ;
    a owl:Class ;
    rdfs:label "pausing variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001213 .

obo:WBPhenotype_0002309
    obo:IAO_0000115 "Animals exhibit a decrease in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002309" ;
    a owl:Class ;
    rdfs:label "pausing decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002308 .

obo:WBPhenotype_0002310
    obo:IAO_0000115 "Animals exhibit an increase in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002310" ;
    a owl:Class ;
    rdfs:label "pausing increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002308 .

obo:WBPhenotype_0002311
    obo:IAO_0000115 "Variations in the behavior by which an organism alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002311" ;
    a owl:Class ;
    rdfs:label "turning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001702 .

obo:WBPhenotype_0002312
    obo:IAO_0000115 "Animals exhibit variations in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002312" ;
    a owl:Class ;
    rdfs:label "turning frequency variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002311 .

obo:WBPhenotype_0002313
    obo:IAO_0000115 "Animals exhibit an increase in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002313" ;
    a owl:Class ;
    rdfs:label "turning frequency increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002312 .

obo:WBPhenotype_0002314
    obo:IAO_0000115 "Animals exhibit a decrease in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002314" ;
    a owl:Class ;
    rdfs:label "turning frequency reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0002312 .

obo:WBPhenotype_0002315
    obo:IAO_0000115 "Animals exhibit variations in their movement at high-speed in the forward direction with brief backward movement compared to control. During roaming, control animals often traverse wide regions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "path range variant" ;
    oboInOwl:id "WBPhenotype:0002315" ;
    a owl:Class ;
    rdfs:label "roaming variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000641, obo:WBPhenotype_0000662 .

obo:WBPhenotype_0002316
    obo:IAO_0000115 "Animals exhibit variations in the low-speed/high turning movement that restricts them to a confined region compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002316" ;
    a owl:Class ;
    rdfs:label "dwelling variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000641, obo:WBPhenotype_0000662 .

obo:WBPhenotype_0002317
    obo:IAO_0000115 "Animals exhibit an increase in the low-speed/high turning movement that usually restricts them to a confined region compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002317" ;
    a owl:Class ;
    rdfs:label "dwelling increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000238, obo:WBPhenotype_0001213, obo:WBPhenotype_0002316 .

obo:WBPhenotype_0002318
    obo:IAO_0000115 "Animals exhibit a decrease in the low-speed/high turning movement that usually restricts them to a confined region compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002318" ;
    a owl:Class ;
    rdfs:label "dwelling reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000237, obo:WBPhenotype_0002316 .

obo:WBPhenotype_0002319
    obo:IAO_0000115 "Animals exhibit an increase in their high-speed movement in the forward direction with brief backward movement compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "path range increased" ;
    oboInOwl:id "WBPhenotype:0002319" ;
    a owl:Class ;
    rdfs:label "roaming increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000237, obo:WBPhenotype_0002315 .

obo:WBPhenotype_0002320
    obo:IAO_0000115 "Variations in the behavior by which an organism shifts from forward to backward movements." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002320" ;
    a owl:Class ;
    rdfs:label "reversal variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001702 .

obo:WBPhenotype_0002321
    obo:IAO_0000115 "Animals exhibit decreased velocity of forward translocation of any point along the animal's track from that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002321" ;
    a owl:Class ;
    rdfs:label "forward point velocity decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0001716 .

obo:WBPhenotype_0002322
    obo:IAO_0000115 "Animals exhibit increased velocity of forward translocation of any point along the animal's track from that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002322" ;
    a owl:Class ;
    rdfs:label "forward point velocity increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001716 .

obo:WBPhenotype_0002323
    obo:IAO_0000115 "Animals exhibit variations in the velocity of backward translocation of any point along the animal's track from that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002323" ;
    a owl:Class ;
    rdfs:label "backward point velocity variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004025 .

obo:WBPhenotype_0002324
    obo:IAO_0000115 "Animals exhibit decreased velocity of backward translocation of any point along the animal's track from that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002324" ;
    a owl:Class ;
    rdfs:label "backward point velocity decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002323 .

obo:WBPhenotype_0002325
    obo:IAO_0000115 "Animals exhibit increased velocity of backward translocation of any point along the animal's track from that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002325" ;
    a owl:Class ;
    rdfs:label "backward point velocity increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002323 .

obo:WBPhenotype_0002326
    obo:IAO_0000115 "Animals exhibit a decrease in the net velocity of an animal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "sluggish" ;
    oboInOwl:id "WBPhenotype:0002326" ;
    a owl:Class ;
    rdfs:label "velocity of movement decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0004025 .

obo:WBPhenotype_0002327
    obo:IAO_0000115 "Animals exhibit an increase in the net velocity of an animal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002327" ;
    a owl:Class ;
    rdfs:label "velocity of movement increased" ;
    rdfs:subClassOf obo:WBPhenotype_0004025 .

obo:WBPhenotype_0002328
    obo:IAO_0000115 "Animals exhibit an increase in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." ;
    oboInOwl:hasExactSynonym "amplitude of body bends increased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002328" ;
    a owl:Class ;
    rdfs:label "amplitude of sinusoidal movement increased" ;
    rdfs:subClassOf obo:WBPhenotype_0004022 .

obo:WBPhenotype_0002329
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0004023 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002329" ;
    a owl:Class ;
    rdfs:label "obsolete temporal frequency of sinusoidal movement variant" ;
    owl:deprecated true .

obo:WBPhenotype_0002330
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0001482 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002330" ;
    a owl:Class ;
    rdfs:label "obsolete temporal frequency of sinusoidal movement decreased" ;
    owl:deprecated true .

obo:WBPhenotype_0002331
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0002348 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002331" ;
    a owl:Class ;
    rdfs:label "obsolete temporal frequency of sinusoidal movement increased" ;
    owl:deprecated true .

obo:WBPhenotype_0002332
    obo:IAO_0000115 "Animals exhibit variations in the length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002332" ;
    a owl:Class ;
    rdfs:label "track length variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000001 .

obo:WBPhenotype_0002333
    obo:IAO_0000115 "Animals exhibit increased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002333" ;
    a owl:Class ;
    rdfs:label "track length increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002332 .

obo:WBPhenotype_0002334
    obo:IAO_0000115 "Animals exhibit decreased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002334" ;
    a owl:Class ;
    rdfs:label "track length decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002332 .

obo:WBPhenotype_0002335
    obo:IAO_0000115 "Animals exhibit variations in the extent to which the overall path of movement is curved, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002335" ;
    a owl:Class ;
    rdfs:label "path curvature variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004017 .

obo:WBPhenotype_0002336
    obo:IAO_0000115 "Animals exhibit increases in the extent to which the overall path of movement is curved, producing tighter and more frequent curves compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002336" ;
    a owl:Class ;
    rdfs:label "path curvature increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002335 .

obo:WBPhenotype_0002337
    obo:IAO_0000115 "Animals exhibit decreases in the extent to which the overall path of movement is curved, producing shallower, less frequent curves and an overall straighter path, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002337" ;
    a owl:Class ;
    rdfs:label "path curvature decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002335 .

obo:WBPhenotype_0002338
    obo:IAO_0000115 "Animals exhibit variations in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002338" ;
    a owl:Class ;
    rdfs:label "body proportion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000231 .

obo:WBPhenotype_0002339
    obo:IAO_0000115 "Animals exhibit increases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002339" ;
    a owl:Class ;
    rdfs:label "body proportion increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002338 .

obo:WBPhenotype_0002340
    obo:IAO_0000115 "Animals exhibit decreases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002340" ;
    a owl:Class ;
    rdfs:label "body proportion decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002338 .

obo:WBPhenotype_0002341
    obo:IAO_0000115 "Animals exhibit variations in instantaneous posture with regards to eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002341" ;
    a owl:Class ;
    rdfs:label "bent posture variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001703 .

obo:WBPhenotype_0002342
    obo:IAO_0000115 "Animals exhibit increased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002342" ;
    a owl:Class ;
    rdfs:label "bent posture increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002341 .

obo:WBPhenotype_0002343
    obo:IAO_0000115 "Animals exhibit decreased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002343" ;
    a owl:Class ;
    rdfs:label "bent posture decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002341 .

obo:WBPhenotype_0002344
    obo:IAO_0000115 "Animals spend less time backing compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002344" ;
    a owl:Class ;
    rdfs:label "backing decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0001005 .

obo:WBPhenotype_0002345
    obo:IAO_0000115 "Variations in the spontaneous or induced forward crawling locomotion of an animal compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002345" ;
    a owl:Class ;
    rdfs:label "forward locomotion variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000643 .

obo:WBPhenotype_0002346
    obo:IAO_0000115 "Animals spend more time in forward locomotion, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002346" ;
    a owl:Class ;
    rdfs:label "forward locomotion increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002345 .

obo:WBPhenotype_0002347
    obo:IAO_0000115 "Animals spend less time in forward locomotion, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002347" ;
    a owl:Class ;
    rdfs:label "forward locomotion decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002345 .

obo:WBPhenotype_0002348
    obo:IAO_0000115 "Animals exhibit an increase in the frequency of oscillations between adjacent body segments from that observed for control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0002331" ;
    oboInOwl:hasExactSynonym "frequency of sinusoidal movement increased", "temporal frequency of sinusoidal movement increased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002348" ;
    a owl:Class ;
    rdfs:label "frequency of body bends increased" ;
    rdfs:subClassOf obo:WBPhenotype_0004023 .

obo:WBPhenotype_0002349
    obo:IAO_0000115 "The levels of phosphatidylinositol 3-phosphate (a.k.a. PtdIns3P or PI3P) are reduced compared to those of control animals" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002349" ;
    a owl:Class ;
    rdfs:label "phosphatidylinositol 3-phosphate levels reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000138 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_26034
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002350
    obo:IAO_0000115 "Animals exhibit increases in steady-state levels of hydrogen peroxide (H2O2) compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002350" ;
    a owl:Class ;
    rdfs:label "hydrogen peroxide levels increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002003 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_16240
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002351
    obo:IAO_0000115 "Animals exhibit reductions in steady-state levels of hydrogen peroxide (H2O2) compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002351" ;
    a owl:Class ;
    rdfs:label "hydrogen peroxide levels reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0002003 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_16240
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002352
    obo:IAO_0000115 "Animals exhibit elevated levels of transfer RNA compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002352" ;
    a owl:Class ;
    rdfs:label "tRNA expression increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000135 .

obo:WBPhenotype_0002353
    obo:IAO_0000115 "Animals exhibit reduced levels of transfer RNA compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002353" ;
    a owl:Class ;
    rdfs:label "tRNA expression decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000134 .

obo:WBPhenotype_0002354
    obo:IAO_0000115 "Animals are more prone to infection from fungal pathogens compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002354" ;
    a owl:Class ;
    rdfs:label "increased susceptibility to fungal infection" ;
    rdfs:subClassOf obo:WBPhenotype_0001013 .

obo:WBPhenotype_0002355
    obo:IAO_0000115 "Animals are more prone to infection by bacterial pathogens compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002355" ;
    a owl:Class ;
    rdfs:label "increased susceptibility to bacterial pathogens" ;
    rdfs:subClassOf obo:WBPhenotype_0001013, obo:WBPhenotype_0002545 .

obo:WBPhenotype_0002356
    obo:IAO_0000115 "Animals are negatively affected by bacteria that is nonpathogenic to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002356" ;
    a owl:Class ;
    rdfs:label "sickened by nonpathogenic bacteria" ;
    rdfs:subClassOf obo:WBPhenotype_0002545 .

obo:WBPhenotype_0002357
    obo:IAO_0000115 "Animals exhibit an increase in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002357" ;
    a owl:Class ;
    rdfs:label "metabolite content increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000463 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_25212
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002358
    obo:IAO_0000115 "The conversion of one differentiated cell type into another does not occur as it does in control animals. In C. elegans, the Y cell undergoes a dramatic redifferentiation from being a cell in of the rectum to a PDA neuron. This transdifferentiation requires the cell to withdraw from its established position, migrate, and then become a motor neuron." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002358" ;
    a owl:Class ;
    rdfs:label "transdifferentiation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001510 .

obo:WBPhenotype_0002359
    obo:IAO_0000115 "Animals exhibit an increase in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002359" ;
    a owl:Class ;
    rdfs:label "protein carbonylation increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002272 .

obo:WBPhenotype_0002360
    obo:IAO_0000115 "Animals respond more severely to cold than control animals subjected to the same cold conditions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002360" ;
    a owl:Class ;
    rdfs:label "cold hypersensitive" ;
    rdfs:subClassOf obo:WBPhenotype_0000146 .

obo:WBPhenotype_0002361
    obo:IAO_0000115 "Animals exhibit increased fluidity of cell membranes, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002361" ;
    a owl:Class ;
    rdfs:label "membrane fluidity increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002484 .

obo:WBPhenotype_0002362
    obo:IAO_0000115 "Variations in the process by which one or more SUMO moieties are added to a protein, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002362" ;
    a owl:Class ;
    rdfs:label "protein sumoylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 .

obo:WBPhenotype_0002363
    obo:IAO_0000115 "Animals are more resistant to the reduction of cholesterol in the environment compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002363" ;
    a owl:Class ;
    rdfs:label "cholesterol depletion resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000725, obo:WBPhenotype_0002525 .

obo:WBPhenotype_0002364
    obo:IAO_0000115 "Spontaneous axon breaks leading to degeneration of separated segments." ;
    oboInOwl:hasExactSynonym "axon degeneration" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002364" ;
    a owl:Class ;
    rdfs:label "axonal degeneration" ;
    rdfs:subClassOf obo:WBPhenotype_0000179 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000639
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030424
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002365
    obo:IAO_0000115 "Following axon damage, animals do not undergo axonal fusion after reconnection between the regrowing axon and its separated segment to the same extent as observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002365" ;
    a owl:Class ;
    rdfs:label "regenerative axonal fusion defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001911 .

obo:WBPhenotype_0002366
    obo:IAO_0000115 "Animals do not suppress exploratory head movements in response to anterior touch stimuli, unlike control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002366" ;
    a owl:Class ;
    rdfs:label "touch-induced suppression of head movement defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0002367
    obo:IAO_0000115 "Animals are less successful than controls in extracting themselves from mesh or other non-living obstructing obstacles." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002367" ;
    a owl:Class ;
    rdfs:label "non-living barrier escape defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000738 .

obo:WBPhenotype_0002368
    obo:IAO_0000115 "Lysosomal refractile bodies are apoptotic-like cell corpse; however, they differ in size and shape and can be described as resembling irregular cell corpses. These bodies have been shown to represent enlarged lysosomes and can occur in conjunction with altered programmed cell death programs." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002368" ;
    a owl:Class ;
    rdfs:label "lysosomal refractile body accumulation" ;
    rdfs:subClassOf obo:WBPhenotype_0002562 .

obo:WBPhenotype_0002369
    obo:IAO_0000115 "Animals exhibit sister cells that have lost otherwise normal asynchrony of cell division timing, compared to control animals. This results in sister cells aberrantly dividing in synchrony." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002369" ;
    a owl:Class ;
    rdfs:label "sister cell division timing asynchrony reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 .

obo:WBPhenotype_0002370
    obo:IAO_0000115 "Animals fail to execute their characteristic movements to avoid noxious heat in a manner consistent with controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002370" ;
    a owl:Class ;
    rdfs:label "noxious heat avoidance defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001273 .

obo:WBPhenotype_0002371
    obo:IAO_0000115 "Vesicles, including those in cells, cell bodies, or synaptic terminals, do not properly form or maintain an intermediate state, such as remain coated with a clathrin coat." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002371" ;
    a owl:Class ;
    rdfs:label "vesicle maturation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001321 .

obo:WBPhenotype_0002372
    obo:IAO_0000115 "Vesicles in the presynaptic terminal differ in size, shape, or composition from those observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002372" ;
    a owl:Class ;
    rdfs:label "presynaptic vesicle morphology altered" ;
    rdfs:subClassOf obo:WBPhenotype_0001323 .

obo:WBPhenotype_0002373
    obo:IAO_0000115 "Animals show a stronger preference for a particular bacterium that has been grown under conditions that differ from a control lawn." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002373" ;
    a owl:Class ;
    rdfs:label "conditional attraction to bacterial lawn" ;
    rdfs:subClassOf obo:WBPhenotype_0000659, obo:WBPhenotype_0002545 .

obo:WBPhenotype_0002374
    obo:IAO_0000115 "Animals are deficient in the transport of silencing RNAs between cells during the systemic RNAi response process." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002374" ;
    a owl:Class ;
    rdfs:label "RNAi transport defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000743 .

obo:WBPhenotype_0002375
    obo:IAO_0000115 "Animals that exhibit paralysis (reduced thrashing) revert back to normal swimming behavior that can be tabulated as a reversion index (number revertants/number paralysis) and reversion probability (time in reversion/time after paralysis)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002375" ;
    a owl:Class ;
    rdfs:label "reversion of swimming paralysis" ;
    rdfs:subClassOf obo:WBPhenotype_0002114 .

obo:WBPhenotype_0002376
    obo:IAO_0000115 "Animals exhibit one or more mRNAs with decreased length of the 3' polyadenine tail, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002376" ;
    a owl:Class ;
    rdfs:label "mRNA poly-A tail length decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0001827 .

obo:WBPhenotype_0002377
    obo:IAO_0000115 "Animals exhibit one or more mRNAs with increased length of the 3' polyadenine tail, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002377" ;
    a owl:Class ;
    rdfs:label "mRNA poly-A tail length increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001827 .

obo:WBPhenotype_0002378
    obo:IAO_0000115 "Variations in the characteristic movement away from specific disease causing agents (pathogens) compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002378" ;
    a owl:Class ;
    rdfs:label "pathogen avoidance variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001012 .

obo:WBPhenotype_0002379
    obo:IAO_0000115 "The subcellular localization of mitochondrial organelles differ from that observed in control cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002379" ;
    a owl:Class ;
    rdfs:label "mitochondria localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002098 .

obo:WBPhenotype_0002380
    obo:IAO_0000115 "Neurons undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles at a faster rate or greater extent than those under conditions that elicit this response in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "increased neurodegeneration" ;
    oboInOwl:id "WBPhenotype:0002380" ;
    a owl:Class ;
    rdfs:label "neuron degeneration enhanced" ;
    rdfs:subClassOf obo:WBPhenotype_0000636 .

obo:WBPhenotype_0002381
    obo:IAO_0000115 "Animals exhibit variations in the amount and/or quality of pheromone produced compared to control animals at a defined stage." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002381" ;
    a owl:Class ;
    rdfs:label "pheromone production variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0002382
    obo:IAO_0000115 "Animals fail to respond to the concentration of a bioactive compound that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.  A bioactive compound is a chemical found in small amounts in organisms or, synthetically produced, that has effects on biological processes in another organism." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002382" ;
    a owl:Class ;
    rdfs:label "resistant to bioactive compound" ;
    rdfs:subClassOf obo:WBPhenotype_0001502 .

obo:WBPhenotype_0002383
    obo:IAO_0000115 "Any variation in the decreased behavioral response to repeated light head or tail touch compared to control. A gentle touch to the animal's head causes backward movement, whereas a gentle touch to the animal's tail causes forward movement. When wild-type animals are touched repeatedly on the head or tail, after some repetition they stop responding to the touch stimulus." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002383" ;
    a owl:Class ;
    rdfs:label "light touch habituation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000626 .

obo:WBPhenotype_0002384
    obo:IAO_0000115 "Animals are resistant to the toxicity of an anti-infective xenobiotic such as R24. Such small molecules protect the host from bacterial infection by inducing antibacterial immune responses via the p38 MAPK pathway. These molecules tend to have toxic effects in addition to immunostimulatory activity." ;
    oboInOwl:hasBroadSynonym "Xts" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "Xenobiotic toxicity resistant" ;
    oboInOwl:id "WBPhenotype:0002384" ;
    a owl:Class ;
    rdfs:label "xenotoxicity suppressor" ;
    rdfs:subClassOf obo:WBPhenotype_0000631 .

obo:WBPhenotype_0002385
    obo:IAO_0000115 "Animals fail to avoid a high pH (alkaline) environment as compared to control animals.  This is at very high pH, for example around pH11." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002385" ;
    a owl:Class ;
    rdfs:label "high pH avoidance defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000523 .

obo:WBPhenotype_0002386
    obo:IAO_0000115 "Animals exhibit variations in the assembly of the fibrous body-membranous organelle (FB-MO), a nematode sperm-specific organelle involved in cytoplasmic partitioning during spermatogenesis, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002386" ;
    a owl:Class ;
    rdfs:label "fibrous body-membranous organelle (FB-MO) assembly variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001344 .

obo:WBPhenotype_0002387
    obo:IAO_0000115 "Dividing cells exhibit additional arrays of microtubules emanating from a spindle pole that do not connect to kinetochores, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002387" ;
    a owl:Class ;
    rdfs:label "supernumerary asters" ;
    rdfs:subClassOf obo:WBPhenotype_0002419, obo:WBPhenotype_0010002 .

obo:WBPhenotype_0002388
    obo:IAO_0000115 "Any variation in the second stage of cell division, between prophase and anaphase, during which the chromosomes become attached to the spindle fibers." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002388" ;
    a owl:Class ;
    rdfs:label "metaphase variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 .

obo:WBPhenotype_0002389
    obo:IAO_0000115 "Any variation in the stage of meiotic or mitotic cell division in which the chromosomes move away from one another to opposite poles of the spindle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002389" ;
    a owl:Class ;
    rdfs:label "anaphase variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 .

obo:WBPhenotype_0002390
    obo:IAO_0000115 "Animals exhibit larger variations in cell division timing events than in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002390" ;
    a owl:Class ;
    rdfs:label "variable cell division timing" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 .

obo:WBPhenotype_0002391
    obo:IAO_0000115 "Cells attempt to divide but fail to form two daughter cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002391" ;
    a owl:Class ;
    rdfs:label "cytokinesis failure" ;
    rdfs:subClassOf obo:WBPhenotype_0002408 .

obo:WBPhenotype_0002392
    obo:IAO_0000115 "A depletion of somatic, but not germline, lipid stores are observed near the end of the reproductive period." ;
    oboInOwl:hasBroadSynonym "Asdf" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002392" ;
    a owl:Class ;
    rdfs:label "age dependent somatic depletion of fat" ;
    rdfs:subClassOf obo:WBPhenotype_0001183 .

obo:WBPhenotype_0002393
    obo:IAO_0000115 "Any variation in the processes that govern the directed extension of neurite projections along the anteroposterior  axis of the animal compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "anteroposterior neurite growth variant" ;
    oboInOwl:id "WBPhenotype:0002393" ;
    a owl:Class ;
    rdfs:label "anterior posterior neurite growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000572 .

obo:WBPhenotype_0002394
    obo:IAO_0000115 "The closure of a phagosome does not occur and it remains connected with the plasma membrane, leaving the lumen open to the outside.  Complete closure usually occurs once an apoptotic cell has been surrounded by an engulfing cell." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002394" ;
    a owl:Class ;
    rdfs:label "phagosome sealing defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000885 .

obo:WBPhenotype_0002395
    obo:IAO_0000115 "Animals exhibit variations in recognition of cell corpses and initiation of corpse engulfment, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002395" ;
    a owl:Class ;
    rdfs:label "corpse engulfment initiation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000243 .

obo:WBPhenotype_0002396
    obo:IAO_0000115 "Animals with a tumorous germline exhibit a decreased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002396" ;
    a owl:Class ;
    rdfs:label "tumor prolapse frequency decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0000038 .

obo:WBPhenotype_0002397
    obo:IAO_0000115 "Animals with a tumorous germline exhibit an increased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002397" ;
    a owl:Class ;
    rdfs:label "tumor prolapse frequency increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000038 .

obo:WBPhenotype_0002398
    obo:IAO_0000115 "Animals exhibit variations in the aggregation behavior of starved L1 larvae, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002398" ;
    a owl:Class ;
    rdfs:label "starved L1 larvae aggregation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001032 .

obo:WBPhenotype_0002399
    obo:IAO_0000115 "Animals exhibit variations in their response to a specific neurotransmitter compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002399" ;
    a owl:Class ;
    rdfs:label "neurotransmitter response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000523 .

obo:WBPhenotype_0002400
    obo:IAO_0000115 "Animals do not live or live poorly in the presence of glucose concentrations that normally do not have an effect on control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002400" ;
    a owl:Class ;
    rdfs:label "glucose intolerant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027, obo:WBPhenotype_0001072 .

obo:WBPhenotype_0002401
    obo:IAO_0000115 "The concentration of fatty acids in the animal are greater than that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002401" ;
    a owl:Class ;
    rdfs:label "excess fatty acids" ;
    rdfs:subClassOf obo:WBPhenotype_0000138 .

obo:WBPhenotype_0002402
    obo:IAO_0000115 "A cell (or group of cells) is not found in the correct body position compared the placement in control animals." ;
    oboInOwl:hasExactSynonym "cell position abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002402" ;
    a owl:Class ;
    rdfs:label "cell position defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000533 .

obo:WBPhenotype_0002403
    obo:IAO_0000115 "Ventral midline blastomeres (P cells) are misaligned (not properly paired) along the ventral midline of larval animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002403" ;
    a owl:Class ;
    rdfs:label "P cell misalignment at ventral midline" ;
    rdfs:subClassOf obo:WBPhenotype_0002402 .

obo:WBPhenotype_0002404
    obo:IAO_0000115 "Cell-cell contacts are abnormal, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "cell cell contacts abnormal" ;
    oboInOwl:id "WBPhenotype:0002404" ;
    a owl:Class ;
    rdfs:label "cell cell contacts abnormal" ;
    rdfs:subClassOf obo:WBPhenotype_0000533 .

obo:WBPhenotype_0002405
    obo:IAO_0000115 "Animals exhibit variations in the behavioral response to pheromones, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002405" ;
    a owl:Class ;
    rdfs:label "pheromone behavioral response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001049 .

obo:WBPhenotype_0002406
    obo:IAO_0000115 "Any neurite that is extended towards the posterior of the animal from neurons that in wild-type animals make only anterior projections (e.g. D-type neurons in C. elegans)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002406" ;
    a owl:Class ;
    rdfs:label "aberrant posteriorly-directed neurite" ;
    rdfs:subClassOf obo:WBPhenotype_0002393 .

obo:WBPhenotype_0002407
    obo:IAO_0000115 "Any variation in the overall size of fertilized oocytes that are laid compared to those laid by control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "egg size abnormal" ;
    oboInOwl:id "WBPhenotype:0002407" ;
    a owl:Class ;
    rdfs:label "egg size variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000037 .

obo:WBPhenotype_0002408
    obo:IAO_0000115 "Any variation that disrupts the cytoplasmic division of a cell during development compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "cytokinesis abnormal" ;
    oboInOwl:id "WBPhenotype:0002408" ;
    a owl:Class ;
    rdfs:label "cytokinesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000910
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002409
    obo:IAO_0000115 "One or more extra cleavage furrows are observed in a cell about to undergo division." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002409" ;
    a owl:Class ;
    rdfs:label "extra cleavage furrow" ;
    rdfs:subClassOf obo:WBPhenotype_0002410 .

obo:WBPhenotype_0002410
    obo:IAO_0000115 "Cells exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002410" ;
    a owl:Class ;
    rdfs:label "cleavage furrow defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002408 .

obo:WBPhenotype_0002411
    obo:IAO_0000115 "Cells exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002411" ;
    a owl:Class ;
    rdfs:label "cleavage furrow initiation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002410 .

obo:WBPhenotype_0002412
    obo:IAO_0000115 "Cells exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002412" ;
    a owl:Class ;
    rdfs:label "cleavage furrow termination defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002410 .

obo:WBPhenotype_0002413
    obo:IAO_0000115 "Animals have more than one nucleus in a particular cell type." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002413" ;
    a owl:Class ;
    rdfs:label "multiple nuclei" ;
    rdfs:subClassOf obo:WBPhenotype_0001894 .

obo:WBPhenotype_0002414
    obo:IAO_0000115 "Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "spindle abnormal" ;
    oboInOwl:id "WBPhenotype:0002414" ;
    a owl:Class ;
    rdfs:label "spindle variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000746 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007051
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002415
    obo:IAO_0000115 "Cells exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002415" ;
    a owl:Class ;
    rdfs:label "spindle assembly defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002414 .

obo:WBPhenotype_0002416
    obo:IAO_0000115 "Any variation in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002416" ;
    a owl:Class ;
    rdfs:label "spindle position variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002414 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051293
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002417
    obo:IAO_0000115 "Any variation in the rotation of the spindle compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002417" ;
    a owl:Class ;
    rdfs:label "spindle rotation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002414 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0051294
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002418
    obo:IAO_0000115 "Cells lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002418" ;
    a owl:Class ;
    rdfs:label "spindle absent" ;
    rdfs:subClassOf obo:WBPhenotype_0002414 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0005819
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002419
    obo:IAO_0000115 "Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a cell cycle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002419" ;
    a owl:Class ;
    rdfs:label "spindle aster variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002414 .

obo:WBPhenotype_0002420
    obo:IAO_0000115 "Animals exhibit variations in the nature and/or extent of chromatin modification, including but not limited to acetylation and/or methylation of histones, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002420" ;
    a owl:Class ;
    rdfs:label "chromatin modification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 .

obo:WBPhenotype_0002421
    obo:IAO_0000115 "Animals exhibit increased ability to survive at low temperatures compared to controls." ;
    oboInOwl:hasExactSynonym "cold tolerant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002421" ;
    a owl:Class ;
    rdfs:label "cold resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000146 .

obo:WBPhenotype_0002422
    obo:IAO_0000115 "Animals respond to tunicamycin at a higher concentration or a longer exposure compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002422" ;
    a owl:Class ;
    rdfs:label "tunicamycin resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0000359 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001650
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CARO_0010004
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002503 ;
                    owl:someValuesFrom obo:CHEBI_29699
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002423
    obo:IAO_0000115 "Animals exhibit variations in response to hypoxia, low oxygen conditions, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002423" ;
    a owl:Class ;
    rdfs:label "hypoxia response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000464 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0001666
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002424
    obo:IAO_0000115 "Animals exhibit variations in response to anoxia, trace oxygen conditions, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002424" ;
    a owl:Class ;
    rdfs:label "anoxia response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000464 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0034059
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002425
    obo:IAO_0000115 "Variations in the specific actions or reactions in response to external or internal stimuli in response to the aggregation of proteins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002425" ;
    a owl:Class ;
    rdfs:label "protein aggregation induced behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001405 .

obo:WBPhenotype_0002426
    obo:IAO_0000115 "The duration of viability in the adult phase of the life-cycle is lowered in response to the aggregation of proteins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002426" ;
    a owl:Class ;
    rdfs:label "protein aggregation induced reduction of life span" ;
    rdfs:subClassOf obo:WBPhenotype_0002425 .

obo:WBPhenotype_0002427
    obo:IAO_0000115 "Variations in the behavioral plasticity induced by the integration of two sensory signals in response to the aggregation of proteins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002427" ;
    a owl:Class ;
    rdfs:label "protein aggregation induced associative learning variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002425 .

obo:WBPhenotype_0002428
    obo:IAO_0000115 "Animals exhibit degeneration of the intestine, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002428" ;
    a owl:Class ;
    rdfs:label "intestinal degeneration" ;
    rdfs:subClassOf obo:WBPhenotype_0000710 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000639
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005772
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002429
    obo:IAO_0000115 "Animals exhibit variations in the degree to which some proteins are glycosylated, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002429" ;
    a owl:Class ;
    rdfs:label "protein glycosylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001382 .

obo:WBPhenotype_0002430
    obo:IAO_0000115 "Any variation in the extent of mitochondrial DNA damage observed compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002430" ;
    a owl:Class ;
    rdfs:label "mitochondrial DNA damage variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000732 .

obo:WBPhenotype_0002431
    obo:IAO_0000115 "A telomerase-independent telomere maintenance pathway that allows for strains to survive in the absence of telomerase." ;
    oboInOwl:hasExactSynonym "ALT" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002431" ;
    a owl:Class ;
    rdfs:label "alternative lengthening of telomeres" ;
    rdfs:subClassOf obo:WBPhenotype_0000879 .

obo:WBPhenotype_0002432
    obo:IAO_0000115 "Animals do not respond with sleeping behavior induced through the EGF pathway. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "stressed-induced sleep variant" ;
    oboInOwl:id "WBPhenotype:0002432" ;
    a owl:Class ;
    rdfs:label "EGF-induced sleep variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001524 .

obo:WBPhenotype_0002433
    obo:IAO_0000115 "Animals respond with sleeping behavior induced through the EGF pathway, more rigorously than control animals. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "stressed-induced sleep resistant" ;
    oboInOwl:id "WBPhenotype:0002433" ;
    a owl:Class ;
    rdfs:label "EGF-induced sleep resistant" ;
    rdfs:subClassOf obo:WBPhenotype_0001524 .

obo:WBPhenotype_0002434
    obo:IAO_0000115 "Animals exhibit variations in their response to mitochondrial stress, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002434" ;
    a owl:Class ;
    rdfs:label "mitochondrial stress response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000142 .

obo:WBPhenotype_0002435
    obo:IAO_0000115 "Nematodes exposed to DNA damaging agents or conditions exhibit lower susceptibility to DNA damage than other animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "induced DNA damage resistant" ;
    oboInOwl:id "WBPhenotype:0002435" ;
    a owl:Class ;
    rdfs:label "less susceptibility to induced DNA damage" ;
    rdfs:subClassOf obo:WBPhenotype_0000739 .

obo:WBPhenotype_0002436
    obo:IAO_0000115 "Nematodes exposed to DNA damaging agents or conditions exhibit greater susceptibility to DNA damage than other animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "induced DNA damage hypersensitive" ;
    oboInOwl:id "WBPhenotype:0002436" ;
    a owl:Class ;
    rdfs:label "high susceptibility to induced DNA damage" ;
    rdfs:subClassOf obo:WBPhenotype_0000739 .

obo:WBPhenotype_0002437
    obo:IAO_0000115 "Animals exhibit variations in the expression of repetitive exogenous DNA compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002437" ;
    a owl:Class ;
    rdfs:label "repetitive transgene expression variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000306 .

obo:WBPhenotype_0002438
    obo:IAO_0000115 "Animals exhibit reduced expression of repetitive exogenous DNA compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002438" ;
    a owl:Class ;
    rdfs:label "repetitive transgene expression reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0002437 .

obo:WBPhenotype_0002439
    obo:IAO_0000115 "Animals exhibit increased expression of repetitive exogenous DNA compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002439" ;
    a owl:Class ;
    rdfs:label "repetitive transgene expression increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002437 .

obo:WBPhenotype_0002440
    obo:IAO_0000115 "Any perturbation that renders sperm incompetent at fertilizing an oocyte." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002440" ;
    a owl:Class ;
    rdfs:label "sperm fertility defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001384 .

obo:WBPhenotype_0002441
    obo:IAO_0000115 "The time between two pumps of the pharynx is increased compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "pharyngeal inter-pumping interval increased" ;
    oboInOwl:id "WBPhenotype:0002441" ;
    a owl:Class ;
    rdfs:label "pharyngeal inter-pump interval increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001006 .

obo:WBPhenotype_0002442
    obo:IAO_0000115 "The duration of the contraction of the pharyngeal muscle during pumping is increased compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "pharyngeal pump extended" ;
    oboInOwl:id "WBPhenotype:0002442" ;
    a owl:Class ;
    rdfs:label "pharyngeal pump duration increased" ;
    rdfs:subClassOf obo:WBPhenotype_0000634 .

obo:WBPhenotype_0002443
    obo:IAO_0000115 "Any variation in the specific actions or reactions of the male that are associated with the protraction of the male copulatory spicules compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002443" ;
    a owl:Class ;
    rdfs:label "spicule protraction variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000279 .

obo:WBPhenotype_0002444
    obo:IAO_0000115 "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases." ;
    oboInOwl:hasExactSynonym "pyrimidine base biosynthesis variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002444" ;
    a owl:Class ;
    rdfs:label "pyrimidine biosynthesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000732 .

obo:WBPhenotype_0002445
    obo:IAO_0000115 "Animals have one or more extra hypodermal cells, which are present in places they are normally not found, when compared to the number and location of these cells in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002445" ;
    a owl:Class ;
    rdfs:label "extra and ectopic hypodermis" ;
    rdfs:subClassOf obo:WBPhenotype_0001303 .

obo:WBPhenotype_0002446
    obo:IAO_0000115 "Animals exhibit variations in pharyngeal pumping rate in response to light, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002446" ;
    a owl:Class ;
    rdfs:label "pharyngeal pumping rate in response to light variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001006, obo:WBPhenotype_0001897 .

obo:WBPhenotype_0002447
    obo:IAO_0000115 "Animals exhibit variations in the acute pharyngeal pumping response to light, during which the pharyngeal pumping rate initially (0-5 seconds after light exposure onset) decreases in response to light, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002447" ;
    a owl:Class ;
    rdfs:label "acute pumping response to light variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002446 .

obo:WBPhenotype_0002448
    obo:IAO_0000115 "Animals exhibit an enhanced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a greater extent than in controls during the first 0-5 seconds after light exposure onset." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002448" ;
    a owl:Class ;
    rdfs:label "enhanced acute pharyngeal pumping response to light" ;
    rdfs:subClassOf obo:WBPhenotype_0002447 .

obo:WBPhenotype_0002449
    obo:IAO_0000115 "Animals exhibit a reduced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a lesser extent than in controls during the first 0-5 seconds after light exposure onset." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002449" ;
    a owl:Class ;
    rdfs:label "reduced acute pharyngeal pumping response to light" ;
    rdfs:subClassOf obo:WBPhenotype_0002447 .

obo:WBPhenotype_0002450
    obo:IAO_0000115 "Animals exhibit variations in the burst pharyngeal pumping response to light, during which the pharyngeal pumping rate slightly increases during the5-10 seconds after light exposure onset, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002450" ;
    a owl:Class ;
    rdfs:label "burst pharyngeal pumping response to light" ;
    rdfs:subClassOf obo:WBPhenotype_0002446 .

obo:WBPhenotype_0002451
    obo:IAO_0000115 "Animals exhibit an enhanced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a greater extent than in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002451" ;
    a owl:Class ;
    rdfs:label "enhanced burst pharyngeal pumping response to light" ;
    rdfs:subClassOf obo:WBPhenotype_0002450 .

obo:WBPhenotype_0002452
    obo:IAO_0000115 "Animals exhibit a reduced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a lesser extent than in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002452" ;
    a owl:Class ;
    rdfs:label "reduced burst pharyngeal pumping response to light" ;
    rdfs:subClassOf obo:WBPhenotype_0002450 .

obo:WBPhenotype_0002453
    obo:IAO_0000115 "Animals exhibit variations in the recovery pharyngeal pumping response to light, during which the pharyngeal pumping rate slowly increases during the 0-10 seconds afterremoval of light exposure, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002453" ;
    a owl:Class ;
    rdfs:label "recovery pumping response to light variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002446 .

obo:WBPhenotype_0002454
    obo:IAO_0000115 "Animals exhibit an enhanced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increases to a greater extent than in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002454" ;
    a owl:Class ;
    rdfs:label "enhanced recovery pumping response to light" ;
    rdfs:subClassOf obo:WBPhenotype_0002453 .

obo:WBPhenotype_0002455
    obo:IAO_0000115 "Animals exhibit a reduced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increasesto a lesser extent than in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002455" ;
    a owl:Class ;
    rdfs:label "reduced recovery pumping response to light" ;
    rdfs:subClassOf obo:WBPhenotype_0002453 .

obo:WBPhenotype_0002456
    obo:IAO_0000115 "Animals exhibit variations in the changes in calcium levels in response to light compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002456" ;
    a owl:Class ;
    rdfs:label "calcium response to light variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001897, obo:WBPhenotype_0002170 .

obo:WBPhenotype_0002457
    obo:IAO_0000115 "Formation in the male of the egg-laying organ of female and hermaphrodite nematodes. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ;
    oboInOwl:hasExactSynonym "vulva in male" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002457" ;
    a owl:Class ;
    rdfs:label "ectopic vulva in male" ;
    rdfs:subClassOf obo:WBPhenotype_0002499 .

obo:WBPhenotype_0002458
    obo:IAO_0000115 "Any variation in the form, structure or composition of any part of an animal caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis." ;
    oboInOwl:hasBroadSynonym "Mal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "maternal effect morphology abnormal" ;
    oboInOwl:id "WBPhenotype:0002458" ;
    a owl:Class ;
    rdfs:label "maternal effect morphology variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000535 .

obo:WBPhenotype_0002459
    obo:IAO_0000115 "Animals exhibit hyperinduction of expression of an antimicrobial peptide after an infection, compared to control animals." ;
    oboInOwl:hasExactSynonym "Hipi" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002459" ;
    a owl:Class ;
    rdfs:label "hyperinduction of antimicrobial peptide expression after infection" ;
    rdfs:subClassOf obo:WBPhenotype_0001800, obo:WBPhenotype_0002539 .

obo:WBPhenotype_0002460
    obo:IAO_0000115 "Animals exhibit no induction of expression of an antimicrobial peptide after an infection, unlike control animals." ;
    oboInOwl:hasExactSynonym "Nipi" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002460" ;
    a owl:Class ;
    rdfs:label "no induction of antimicrobial peptide expression after infection" ;
    rdfs:subClassOf obo:WBPhenotype_0001800, obo:WBPhenotype_0002621 .

obo:WBPhenotype_0002461
    obo:IAO_0000115 "Pathogens exhibit decreased adherence to the surface of host animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002461" ;
    a owl:Class ;
    rdfs:label "pathogen adherence decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0001415 .

obo:WBPhenotype_0002462
    obo:IAO_0000115 "Pathogens exhibit increased adherence to the surface of host animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002462" ;
    a owl:Class ;
    rdfs:label "pathogen adherence increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001415 .

obo:WBPhenotype_0002463
    obo:IAO_0000115 "Male animals lack a copulatory hook." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002463" ;
    a owl:Class ;
    rdfs:label "hookless" ;
    rdfs:subClassOf obo:WBPhenotype_0002209 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0008425
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002464
    obo:IAO_0000115 "Male animals exhibit multiple copulatory hooks. In wild type C. elegans males, a single hook is normally present." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002464" ;
    a owl:Class ;
    rdfs:label "multiple hooks" ;
    rdfs:subClassOf obo:WBPhenotype_0002209 .

obo:WBPhenotype_0002465
    obo:IAO_0000115 "The pattern or state of ubiquitin modifications of histones varies from that of controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "histone ubiquitylation variant" ;
    oboInOwl:id "WBPhenotype:0002465" ;
    a owl:Class ;
    rdfs:label "histone ubiquitination variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001865 .

obo:WBPhenotype_0002466
    obo:IAO_0000115 "Variations in the processes that incorporate methyl groups to one or more bases within RNA, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002466" ;
    a owl:Class ;
    rdfs:label "RNA methylation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001827 .

obo:WBPhenotype_0002467
    obo:IAO_0000115 "Males continue to sire progeny significantly past the time reproduction stops in control animals or show a slower decline in mating efficiency compared to age-matched control males." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002467" ;
    a owl:Class ;
    rdfs:label "male reproductive longevity extended" ;
    rdfs:subClassOf obo:WBPhenotype_0001739 .

obo:WBPhenotype_0002468
    obo:IAO_0000115 "Animals exhibit a reduction in the rate of the chemical reactions and pathways resulting in the formation of a protein, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002468" ;
    a owl:Class ;
    rdfs:label "translation rate reduced" ;
    rdfs:subClassOf obo:WBPhenotype_0000121 .

obo:WBPhenotype_0002469
    obo:IAO_0000115 "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002469" ;
    a owl:Class ;
    rdfs:label "plate tap habituation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000626 .

obo:WBPhenotype_0002470
    obo:IAO_0000115 "Animals exhibit variations in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." ;
    oboInOwl:hasExactSynonym "cilium length variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002470" ;
    a owl:Class ;
    rdfs:label "cilia length variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000615 .

obo:WBPhenotype_0002471
    obo:IAO_0000115 "Animals exhibit an increase in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." ;
    oboInOwl:hasExactSynonym "cilium length increased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002471" ;
    a owl:Class ;
    rdfs:label "cilia length increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002470 .

obo:WBPhenotype_0002472
    obo:IAO_0000115 "Animals exhibit a reduction in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." ;
    oboInOwl:hasExactSynonym "cilium length decreased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002472" ;
    a owl:Class ;
    rdfs:label "cilia length decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002470 .

obo:WBPhenotype_0002473
    obo:IAO_0000115 "Animals fail to undergo the cellular catabolic process in which cells digest parts of their own cytoplasm." ;
    oboInOwl:hasExactSynonym "autophagy defective" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002473" ;
    a owl:Class ;
    rdfs:label "autophagy block" ;
    rdfs:subClassOf obo:WBPhenotype_0002283 .

obo:WBPhenotype_0002474
    obo:IAO_0000115 "Animals are less prone to infection by virus compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002474" ;
    a owl:Class ;
    rdfs:label "viral resistance increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001014 .

obo:WBPhenotype_0002475
    obo:IAO_0000115 "Animals vary in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals." ;
    oboInOwl:hasExactSynonym "pharyngeal length variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002475" ;
    a owl:Class ;
    rdfs:label "pharynx length variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000709 .

obo:WBPhenotype_0002476
    obo:IAO_0000115 "Animals have an increase in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals." ;
    oboInOwl:hasExactSynonym "pharyngeal length increased", "pharynx elongation" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002476" ;
    a owl:Class ;
    rdfs:label "pharynx length increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002475 .

obo:WBPhenotype_0002477
    obo:IAO_0000115 "Any variation in the subcellular localization of the ribosome compared to control. The ribosome is an intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA)." ;
    oboInOwl:hasExactSynonym "ribosome distribution variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002477" ;
    a owl:Class ;
    rdfs:label "ribosome localization variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002098 .

obo:WBPhenotype_0002478
    obo:IAO_0000115 "Any variation in the cellular and molecular pathways in a neuron in response to having its axon severed compared to severing in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002478" ;
    a owl:Class ;
    rdfs:label "axotomy response variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002563 .

obo:WBPhenotype_0002479
    obo:IAO_0000115 "Any increase in regenerative regrowth of axons compared to control animals." ;
    oboInOwl:hasExactSynonym "axonal regeneration enhanced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002479" ;
    a owl:Class ;
    rdfs:label "axon regeneration enhanced" ;
    rdfs:subClassOf obo:WBPhenotype_0000880 .

obo:WBPhenotype_0002480
    obo:IAO_0000115 "Animals exhibit variations in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002480" ;
    a owl:Class ;
    rdfs:label "heme levels variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000027 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000070
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_30413
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002481
    obo:IAO_0000115 "Animals exhibit a decrease in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." ;
    oboInOwl:hasExactSynonym "heme levels reduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002481" ;
    a owl:Class ;
    rdfs:label "heme levels decreased" ;
    rdfs:subClassOf obo:WBPhenotype_0002480 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_30413
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002482
    obo:IAO_0000115 "Animals exhibit an increase in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002482" ;
    a owl:Class ;
    rdfs:label "heme levels increased" ;
    rdfs:subClassOf obo:WBPhenotype_0002480 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_30413
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002483
    obo:IAO_0000115 "Animals are less prone to infection by a fungus compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002483" ;
    a owl:Class ;
    rdfs:label "fungal resistance increased" ;
    rdfs:subClassOf obo:WBPhenotype_0001014 .

obo:WBPhenotype_0002484
    obo:IAO_0000115 "Animals exhibit variations in fluidity of cell membranes, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002484" ;
    a owl:Class ;
    rdfs:label "membrane fluidity variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001965 .

obo:WBPhenotype_0002485
    obo:IAO_0000115 "Any variation in the morphological appearance of germline precursor cells compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "primordial germ cell morphology variant" ;
    oboInOwl:id "WBPhenotype:0002485" ;
    a owl:Class ;
    rdfs:label "germline precursor cell morphology variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002108 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006849
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002486
    obo:IAO_0000115 "Animals exhibit persistent cellular lobes of the primordial germ cells Z2 and/or Z3 at the L1 larval stage or later, in contrast to wild type animals" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "persistent germline precursor cell lobes" ;
    oboInOwl:id "WBPhenotype:0002486" ;
    a owl:Class ;
    rdfs:label "persistent primordial germ cell lobes"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002485 .

obo:WBPhenotype_0002487
    obo:IAO_0000115 "Animals exhibit variations in the integrity of the intestine, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002487" ;
    a owl:Class ;
    rdfs:label "intestinal integrity variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001093 .

obo:WBPhenotype_0002488
    obo:IAO_0000115 "Animals exhibit an increase in the integrity of the intestine, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002488" ;
    a owl:Class ;
    rdfs:label "intestinal integrity increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002487 .

obo:WBPhenotype_0002489
    obo:IAO_0000115 "Animals exhibit a reduction in the integrity of the intestine, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002489" ;
    a owl:Class ;
    rdfs:label "intestinal integrity reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002487 .

obo:WBPhenotype_0002490
    obo:IAO_0000115 "Neurons exhibit axon outgrowth in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002490" ;
    a owl:Class ;
    rdfs:label "ectopic axon outgrowth"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001224, obo:WBPhenotype_0002491 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030424
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002491
    obo:IAO_0000115 "Neurons exhibit neurite outgrowth in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002491" ;
    a owl:Class ;
    rdfs:label "ectopic neurite outgrowth"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000572 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043005
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002492
    obo:IAO_0000115 "Animals exhibit one or more body wall muscle cells in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002492" ;
    a owl:Class ;
    rdfs:label "ectopic body wall muscle"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002493 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006804
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002493
    obo:IAO_0000115 "Animals exhibit one or more cells of a particular type in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002493" ;
    a owl:Class ;
    rdfs:label "ectopic cell"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000529 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004017
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002494
    obo:IAO_0000115 "Animals exhibit one or more endodermal cells in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002494" ;
    a owl:Class ;
    rdfs:label "ectopic endoderm"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002493 .

obo:WBPhenotype_0002495
    obo:IAO_0000115 "Animals exhibit one or more hypodermal cells in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002495" ;
    a owl:Class ;
    rdfs:label "ectopic hypodermis"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002493 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005733
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002496
    obo:IAO_0000115 "Animals exhibit one or more neurons in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002496" ;
    a owl:Class ;
    rdfs:label "ectopic neuron"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002493 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003679
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002497
    obo:IAO_0000115 "Animals exhibit one or more pharyngeal muscle cells in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002497" ;
    a owl:Class ;
    rdfs:label "ectopic pharyngeal muscle"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002493 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005451
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002498
    obo:IAO_0000115 "Animals exhibit one or more organs of a particular type in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002498" ;
    a owl:Class ;
    rdfs:label "ectopic organ"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000530 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003760
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002499
    obo:IAO_0000115 "Animals exhibit one or more vulvae in locations not normally found in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002499" ;
    a owl:Class ;
    rdfs:label "ectopic vulva"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002498 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0006748
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002500
    obo:IAO_0000115 "One or more cells exhibit one or more cleavage furrows in locations not normally found in control cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002500" ;
    a owl:Class ;
    rdfs:label "ectopic cleavage furrow"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002410 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000628
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0032154
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002501
    obo:IAO_0000115 "One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002501" ;
    a owl:Class ;
    rdfs:label "ectopic cleavage furrow early emb"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001129 .

obo:WBPhenotype_0002502
    obo:IAO_0000115 "Animals exhibit an increase in the covalent addition of an acetyl group to one or more native amino acid side chains in proteins." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002502" ;
    a owl:Class ;
    rdfs:label "protein acetylation increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001917 .

obo:WBPhenotype_0002503
    obo:IAO_0000115 "Animals exhibit an increase the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002503" ;
    a owl:Class ;
    rdfs:label "meiotic DNA double strand break formation increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001921 .

obo:WBPhenotype_0002504
    obo:IAO_0000115 "Infected animals exhibit a reduction in the release of pathogens back into the environment, compared to control." ;
    oboInOwl:hasNarrowSynonym "spore shedding reduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002504" ;
    a owl:Class ;
    rdfs:label "pathogen release reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002172 .

obo:WBPhenotype_0002505
    obo:IAO_0000115 "Infected animals exhibit variations in the clearance of pathogen infection compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002505" ;
    a owl:Class ;
    rdfs:label "pathogen infection clearance variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002164 .

obo:WBPhenotype_0002506
    obo:IAO_0000115 "Infected animals exhibit an increased rate of clearance of pathogen infection compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002506" ;
    a owl:Class ;
    rdfs:label "pathogen infection clearance rate increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002505 .

obo:WBPhenotype_0002507
    obo:IAO_0000115 "Infected animals exhibit a decreased rate of clearance of pathogen infection compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002507" ;
    a owl:Class ;
    rdfs:label "pathogen infection clearance rate decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002505 .

obo:WBPhenotype_0002508
    obo:IAO_0000115 "Animals produce an excess number of neurons compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002508" ;
    a owl:Class ;
    rdfs:label "extra neuron"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002175 .

obo:WBPhenotype_0002509
    obo:IAO_0000115 "Animals produce an excess number of dopaminergic neurons compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002509" ;
    a owl:Class ;
    rdfs:label "extra dopaminergic neuron"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002508 .

obo:WBPhenotype_0002510
    obo:IAO_0000115 "Animals exhibit fewer neurons compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002510" ;
    a owl:Class ;
    rdfs:label "fewer neurons"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000623, obo:WBPhenotype_0002174 .

obo:WBPhenotype_0002511
    obo:IAO_0000115 "Animals exhibit fewer glutamatergic neurons compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002511" ;
    a owl:Class ;
    rdfs:label "fewer glutamatergic neurons"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002510 .

obo:WBPhenotype_0002512
    obo:IAO_0000115 "Variations in behavior that is dependent upon the sensation of temperature, compared to control." ;
    oboInOwl:hasNarrowSynonym "thermosensory behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002512" ;
    a owl:Class ;
    rdfs:label "thermosensory behavior variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000525 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040040
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002513
    obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific temperature gradient compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002513" ;
    a owl:Class ;
    rdfs:label "thermotaxis variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002512 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043052
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002514
    obo:IAO_0000115 "Animals do not exhibit backward locomotion under conditions that induce backward locomotion in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002514" ;
    a owl:Class ;
    rdfs:label "backing absent"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001005 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000462
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0043057
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002515
    obo:IAO_0000115 "Animals exhibit a defective response to pathogens." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002515" ;
    a owl:Class ;
    rdfs:label "organism pathogen response defective"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001012 .

obo:WBPhenotype_0002516
    obo:IAO_0000115 "Animals exhibit variations, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Variations in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect variations in neuromuscular efficacy of locomotion." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002516" ;
    a owl:Class ;
    rdfs:label "burrowing assay distance abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002559 .

obo:WBPhenotype_0002517
    obo:IAO_0000115 "Animals exhibit a reduction, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Reductions in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect deficits in neuromuscular efficacy of locomotion." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002517" ;
    a owl:Class ;
    rdfs:label "burrowing assay distance reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002516 .

obo:WBPhenotype_0002518
    obo:IAO_0000115 "The length of one or more axons is abnormal compared to the length of the corresponding axon(s) in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002518" ;
    a owl:Class ;
    rdfs:label "axon length abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000180 .

obo:WBPhenotype_0002519
    obo:IAO_0000115 "The length of one or more axons is reduced compared to the length of the corresponding axon(s) in control animals." ;
    oboInOwl:hasExactSynonym "short axon" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002519" ;
    a owl:Class ;
    rdfs:label "axon length reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002518 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000574
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030424
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002520
    obo:IAO_0000115 "One or more cells exhibit variations in the morphology of one or more gap junction plaques, sets of associated gap junctions, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002520" ;
    a owl:Class ;
    rdfs:label "gap junction plaque morphology abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001658 .

obo:WBPhenotype_0002521
    obo:IAO_0000115 "One or more cells exhibit an increase in number of gap junction plaques, sets of associated gap junctions, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002521" ;
    a owl:Class ;
    rdfs:label "gap junction plaque number increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002520 .

obo:WBPhenotype_0002522
    obo:IAO_0000115 "Animals exhibit variations in the recovery from L1 larvae developmental arrest in response to a lack of food (starvation) available in the environment." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002522" ;
    a owl:Class ;
    rdfs:label "starvation-induced L1 arrest recovery abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000751 .

obo:WBPhenotype_0002523
    obo:IAO_0000115 "Animals exhibit a slow recovery from starvation-induced L1 arrest, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002523" ;
    a owl:Class ;
    rdfs:label "slow recovery from starvation-induced L1 arrest"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002522 .

obo:WBPhenotype_0002524
    obo:IAO_0000115 "Animals are more sensitive to the depletion of molybdenum cofactor from the diet compared to control animals." ;
    oboInOwl:hasExactSynonym "dependent on dietary molybdenum cofactor" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002524" ;
    a owl:Class ;
    rdfs:label "molybdenum cofactor depletion hypersensitive"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002526 .

obo:WBPhenotype_0002525
    obo:IAO_0000115 "Animals exhibit variations in their response to diet, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002525" ;
    a owl:Class ;
    rdfs:label "diet response variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000027 .

obo:WBPhenotype_0002526
    obo:IAO_0000115 "Animals exhibit variations in the response to the depletion of molybdenum cofactor from the diet compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002526" ;
    a owl:Class ;
    rdfs:label "response to molybdenum cofactor depletion abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002525 .

obo:WBPhenotype_0002527
    obo:IAO_0000115 "Animals in the dauer larval stage exhibit variations in their physiology (any biological process including but not limited to development, behavior, or metabolism) compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002527" ;
    a owl:Class ;
    rdfs:label "dauer larva physiology variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001293 .

obo:WBPhenotype_0002528
    obo:IAO_0000115 "Animals (or cells) exhibit defects in the ability to produce mature microRNAs (miRNAs) from a miRNA locus. The defects could be at the level of miRNA transcription, pri-miRNA processing, and/or pre-miRNA processing." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002528" ;
    a owl:Class ;
    rdfs:label "miRNA biogenesis defective"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001779 .

obo:WBPhenotype_0002529
    obo:IAO_0000115 "Animals exhibit defects or impairments in the functioning of the proteasome." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002529" ;
    a owl:Class ;
    rdfs:label "proteasome defective"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002009 .

obo:WBPhenotype_0002530
    obo:IAO_0000115 "The level of phosphatidylserine exposed on the external axonal membrane following transection (axotomy) is changed compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002530" ;
    a owl:Class ;
    rdfs:label "axotomy-induced phosphatidylserine exposure abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001399, obo:WBPhenotype_0002478 .

obo:WBPhenotype_0002531
    obo:IAO_0000115 "Animals exhibit variations in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002531" ;
    a owl:Class ;
    rdfs:label "allophagy abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000736 .

obo:WBPhenotype_0002532
    obo:IAO_0000115 "Animals exhibit defects in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002532" ;
    a owl:Class ;
    rdfs:label "allophagy defective"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002531 .

obo:WBPhenotype_0002534
    obo:IAO_0000115 "Animals exhibit variations in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002534" ;
    a owl:Class ;
    rdfs:label "antimicrobial gene expression variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0002535
    obo:IAO_0000115 "Animals exhibit variations in the extent to which one or more sensory neurons associated with sensilla (typically one or more amphids and/or phasmids) take up dye from the environment, compared to controls. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." ;
    oboInOwl:hasExactSynonym "Dyf", "dye filling abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002535" ;
    a owl:Class ;
    rdfs:label "dye filling defect"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000255 .

obo:WBPhenotype_0002536
    obo:IAO_0000115 "Animals exhibit germ cells with a number of P granules that differs from control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002536" ;
    a owl:Class ;
    rdfs:label "P granule number abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001300 .

obo:WBPhenotype_0002537
    obo:IAO_0000115 "Animals exhibit germ cells with a reduced number of P granules compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002537" ;
    a owl:Class ;
    rdfs:label "P granule number reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002536 .

obo:WBPhenotype_0002538
    obo:IAO_0000115 "Any variation in the series of molecular signals in which the spermatheca uses calcium ions to convert an extracellular signal into a response, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002538" ;
    a owl:Class ;
    rdfs:label "calcium signaling in spermatheca variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002170 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0019722
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0005319
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002539
    obo:IAO_0000115 "Animals exhibit an increase in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002539" ;
    a owl:Class ;
    rdfs:label "antimicrobial gene expression increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002534 .

obo:WBPhenotype_0002540
    obo:IAO_0000115 "Animals exhibit a reduced rate of lawn/food leaving events, compared to controls." ;
    oboInOwl:hasExactSynonym "food leaving reduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002540" ;
    a owl:Class ;
    rdfs:label "lawn leaving reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001983 .

obo:WBPhenotype_0002541
    obo:IAO_0000115 "Programmed cell death of germ cells caused by exposure to ionizing energy occurs to a lesser extent than it does in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002541" ;
    a owl:Class ;
    rdfs:label "radiation induced germ cell apoptosis resistant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001850 .

obo:WBPhenotype_0002542
    obo:IAO_0000115 "Cells exhibit specific regions of chromatin (e.g. an integrated array reporter) that localize to different regions within the nucleus, compared to controls." ;
    oboInOwl:hasExactSynonym "intranuclear chromatin localization abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002542" ;
    a owl:Class ;
    rdfs:label "intranuclear chromatin localization variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001348 .

obo:WBPhenotype_0002543
    obo:IAO_0000115 "Animals accumulate a greater number of mitochondrial genetic lesions than control animals in the absence of an externally controlled mutagen." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002543" ;
    a owl:Class ;
    rdfs:label "spontaneous mitochondrial DNA mutation rate increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000228 .

obo:WBPhenotype_0002544
    obo:IAO_0000115 "Normally beneficial (or otherwise harmless, non-pathogenic) commensal Enterobacter bacteria, for example Enterobacter cloacae, become pathogenic to animals, unlike in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002544" ;
    a owl:Class ;
    rdfs:label "hypersensitive to Enterobacter commensals"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002356 .

obo:WBPhenotype_0002545
    obo:IAO_0000115 "Animals exhibit variations in their response to bacteria (pathogenic or non-pathogenic), compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002545" ;
    a owl:Class ;
    rdfs:label "response to bacteria variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000738 .

obo:WBPhenotype_0002546
    obo:IAO_0000115 "Animals exhibit variations in the load of bacteria, of a particular clade or in general, in the gut, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002546" ;
    a owl:Class ;
    rdfs:label "bacterial load in gut variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002545 .

obo:WBPhenotype_0002547
    obo:IAO_0000115 "Animals exhibit a greater abundance of bacteria of the Enterobacteriaceae family in the gut, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002547" ;
    a owl:Class ;
    rdfs:label "gut Enterobacteriaceae bloom"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002546 .

obo:WBPhenotype_0002548
    obo:IAO_0000115 "Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves." ;
    oboInOwl:hasExactSynonym "conflicted kinker" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002548" ;
    a owl:Class ;
    rdfs:label "kinker from conflicting forward and backward body bend propagation"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000002 .

obo:WBPhenotype_0002549
    obo:IAO_0000115 "Animals exhibit an increase in the rate at which spontaneous backward locomotion is initiated compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002549" ;
    a owl:Class ;
    rdfs:label "increased frequency of spontaneous reversal initiation"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001506 .

obo:WBPhenotype_0002550
    obo:IAO_0000115 "Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves, and over time has a tendency to move slowly backward due to a dominating reversal neural circuit." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002550" ;
    a owl:Class ;
    rdfs:label "conflicted kinker with gradual backward movement"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002548 .

obo:WBPhenotype_0002551
    obo:IAO_0000115 "A phenotype affecting a particular anatomical entity." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002551" ;
    a owl:Class ;
    rdfs:label "anatomical phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002314 ;
                    owl:someValuesFrom obo:WBbt_0000100
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002552
    obo:IAO_0000115 "A phenotype affecting a particular cell." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002552" ;
    a owl:Class ;
    rdfs:label "cell phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0004017
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002553
    obo:IAO_0000115 "A phenotype affecting a particular organ." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002553" ;
    a owl:Class ;
    rdfs:label "organ phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0003760
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002554
    obo:IAO_0000115 "A phenotype affecting a particular organ system." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002554" ;
    a owl:Class ;
    rdfs:label "organ system phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005746
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002555
    obo:IAO_0000115 "A phenotype affecting the whole organism." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002555" ;
    a owl:Class ;
    rdfs:label "organismal phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0007833
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002556
    obo:IAO_0000115 "A phenotype affecting a particular tissue." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002556" ;
    a owl:Class ;
    rdfs:label "tissue phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005729
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002557
    obo:IAO_0000115 "A phenotype affecting a particular body region." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002557" ;
    a owl:Class ;
    rdfs:label "body region phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005738
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002558
    obo:IAO_0000115 "A phenotype affecting a particular extracellular component." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002558" ;
    a owl:Class ;
    rdfs:label "extracellular component phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000886 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000001
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005732
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002559
    obo:IAO_0000115 "Animals exhibit abnormalities in their burrowing behavior, in which animals burrow into a solid medium, such as agar, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002559" ;
    a owl:Class ;
    rdfs:label "burrowing abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000643 .

obo:WBPhenotype_0002560
    obo:IAO_0000115 "Greater quantities of worms burrow into and stay below the surface of the agar when high densities of nematodes are maintained on agar compared to controls (Hodgkin and Doniach, 1997)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002560" ;
    a owl:Class ;
    rdfs:label "burrowing in response to high population density increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002559 .

obo:WBPhenotype_0002561
    obo:IAO_0000115 "Cells exhibit defects in the homotypic fusion of endosomes." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001638" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002561" ;
    a owl:Class ;
    rdfs:label "homotypic endosome fusion defective"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001422 .

obo:WBPhenotype_0002562
    obo:IAO_0000115 "Cells exhibit variations or abnormalities in their maintenance of lysosome function, compared to controls." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0001784" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002562" ;
    a owl:Class ;
    rdfs:label "lysosome homeostasis abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0002563
    obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the neuron to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0000991" ;
    oboInOwl:hasExactSynonym "neuron physiology abnormal", "neuron physiology variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002563" ;
    a owl:Class ;
    rdfs:label "neuron physiology phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:GO_0008150
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000066 ;
                                owl:someValuesFrom obo:WBbt_0003679
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002564
    obo:IAO_0000115 "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms, compared to controls." ;
    oboInOwl:hasExactSynonym "associative memory abnormal", "associative memory variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002564" ;
    a owl:Class ;
    rdfs:label "associative memory phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000738 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0007613
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002565
    obo:IAO_0000115 "Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms, compared to controls." ;
    oboInOwl:hasExactSynonym "olfactory memory abnormal", "olfactory memory variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002565" ;
    a owl:Class ;
    rdfs:label "associative olfactory memory phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002564 .

obo:WBPhenotype_0002566
    obo:IAO_0000115 "Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." ;
    oboInOwl:hasExactSynonym "long-term associative olfactory memory abnormal", "long-term associative olfactory memory variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002566" ;
    a owl:Class ;
    rdfs:label "long-term associative olfactory memory phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002565, obo:WBPhenotype_0002568 .

obo:WBPhenotype_0002567
    obo:IAO_0000115 "Animals are deficient in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002567" ;
    a owl:Class ;
    rdfs:label "long-term associative olfactory memory defective"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001785, obo:WBPhenotype_0002566 .

obo:WBPhenotype_0002568
    obo:IAO_0000115 "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." ;
    oboInOwl:hasExactSynonym "long-term associative memory abnormal", "long-term associative memory variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002568" ;
    a owl:Class ;
    rdfs:label "long-term associative memory phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002564 .

obo:WBPhenotype_0002569
    obo:IAO_0000115 "Any variation in the progression of the hypodermis over time, from its formation to its mature state compared to control." ;
    oboInOwl:hasExactSynonym "hypodermal development abnormal", "hypodermal development variant", "hypodermis development abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002569" ;
    a owl:Class ;
    rdfs:label "hypodermis development variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000701 .

obo:WBPhenotype_0002570
    obo:IAO_0000115 "Cessation of development during the gastrulation stage of embryonic development. In C. elegans, gastrulation occurs 100-290 minutes after first cleavage at 20 degrees Centigrade when the embryo develops from 28 cells to 421 cells (during the proliferating embryo life stage)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002570" ;
    a owl:Class ;
    rdfs:label "embryonic arrest during gastrulation"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000867 .

obo:WBPhenotype_0002571
    obo:IAO_0000115 "Embryos exhibit a failure to enclose the anterior embryo region with hypodermis during the comma to early elongation stage of embryonic development." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002571" ;
    a owl:Class ;
    rdfs:label "anterior enclosure defective"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001566 .

obo:WBPhenotype_0002572
    obo:IAO_0000115 "Animals exhibit variations in mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control." ;
    oboInOwl:hasExactSynonym "mitophagy variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002572" ;
    a owl:Class ;
    rdfs:label "mitophagy abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000736 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000423
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002573
    obo:IAO_0000115 "Animals exhibit reduced levels of mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002573" ;
    a owl:Class ;
    rdfs:label "mitophagy reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002572 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002052
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0000423
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002574
    obo:IAO_0000115 "Animals exhibit abnormal amounts of variation in gene expression level between individual animals, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002574" ;
    a owl:Class ;
    rdfs:label "gene expression level variation abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0002575
    obo:IAO_0000115 "Animals exhibit abnormal gene expression levels, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002575" ;
    a owl:Class ;
    rdfs:label "gene expression level abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000717 .

obo:WBPhenotype_0002576
    obo:IAO_0000115 "Animals exhibit reduced amounts of variation in gene expression level between individual animals, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002576" ;
    a owl:Class ;
    rdfs:label "gene expression level variation reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002574 .

obo:WBPhenotype_0002577
    obo:IAO_0000115 "Animals exhibit variations in the composition of basement membranes, compared to control animals." ;
    oboInOwl:hasExactSynonym "basement membrane composition abnormal", "basement membrane composition variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002577" ;
    a owl:Class ;
    rdfs:label "basement membrane composition phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002588 .

obo:WBPhenotype_0002578
    obo:IAO_0000115 "Animals exhibit variations in the amount of laminin in basement membranes, compared to control animals." ;
    oboInOwl:hasExactSynonym "basement membrane laminin level abnormal", "basement membrane laminin level variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002578" ;
    a owl:Class ;
    rdfs:label "basement membrane laminin level phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002577 .

obo:WBPhenotype_0002579
    obo:IAO_0000115 "Animals exhibit variations in the amount of type IV collagen in basement membranes, compared to control animals." ;
    oboInOwl:hasExactSynonym "basement membrane type IV collagen level abnormal", "basement membrane type IV collagen level variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002579" ;
    a owl:Class ;
    rdfs:label "basement membrane type IV collagen level phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002577 .

obo:WBPhenotype_0002580
    obo:IAO_0000115 "One or more cells exhibit changes in the variability of cell position, compared to controls." ;
    oboInOwl:hasExactSynonym "cell position variability abnormal", "cell position variability variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002580" ;
    a owl:Class ;
    rdfs:label "cell position variability phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000533 .

obo:WBPhenotype_0002581
    obo:IAO_0000115 "One or more cells exhibit increases in the variability of cell position, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002581" ;
    a owl:Class ;
    rdfs:label "cell position variability increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002580 .

obo:WBPhenotype_0002582
    obo:IAO_0000115 "Animals exhibit variations in miniature inhibitory post-synaptic currents (mIPSC), compared to controls." ;
    oboInOwl:hasExactSynonym "mIPSC abnormal", "mIPSC phenotype", "mIPSC variant", "miniature inhibitory post-synaptic current abnormal", "miniature inhibitory post-synaptic current variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002582" ;
    a owl:Class ;
    rdfs:label "miniature inhibitory post-synaptic current phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002014 .

obo:WBPhenotype_0002583
    obo:IAO_0000115 "Animals exhibit increased amplitude of miniature inhibitory post-synaptic currents (mIPSC), compared to controls." ;
    oboInOwl:hasExactSynonym "mIPSC amplitude increased" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002583" ;
    a owl:Class ;
    rdfs:label "miniature inhibitory post-synaptic current amplitude increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002582 .

obo:WBPhenotype_0002584
    obo:IAO_0000115 "Animals survive longer, or do not respond to the same degree as control animals under similar conditions of bisphenol A exposure." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002584" ;
    a owl:Class ;
    rdfs:label "bisphenol A resistant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000931 .

obo:WBPhenotype_0002585
    obo:IAO_0000115 "Pristionchus pacificus: Animals exhibit abnormal predatory behavior, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002585" ;
    a owl:Class ;
    rdfs:label "predatory behavior abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000525 .

obo:WBPhenotype_0002586
    obo:IAO_0000115 "Pristionchus pacificus: Animals exhibit reduced predatory feeding behavior, indicated by reduced predation success, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002586" ;
    a owl:Class ;
    rdfs:label "reduced predatory feeding behavior"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002585 .

obo:WBPhenotype_0002587
    obo:IAO_0000115 "Animals are impaired in their burrowing ability compared to control animals in a Pluronic gel-based burrowing assay." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002587" ;
    a owl:Class ;
    rdfs:label "Pluronic gel burrowing impaired"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002559 .

obo:WBPhenotype_0002588
    obo:IAO_0000115 "Animals exhibit variations or abnormalities in the structure, integrity, function, or quality of basement membranes, compared to controls." ;
    oboInOwl:hasExactSynonym "basement membrane abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002588" ;
    a owl:Class ;
    rdfs:label "basement membrane phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001210 .

obo:WBPhenotype_0002589
    obo:IAO_0000115 "Animals exhibit a reduction in neuron degeneration, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002589" ;
    a owl:Class ;
    rdfs:label "neuron degeneration reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000636 .

obo:WBPhenotype_0002590
    obo:IAO_0000115 "The linker cell of male animals becomes detached from the rest of the male gonad." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002590" ;
    a owl:Class ;
    rdfs:label "linker cell detached"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001675 .

obo:WBPhenotype_0002591
    obo:IAO_0000115 "One or more neurons of the animal exhibit one or more dendrites with reduced length compared to the corresponding dendrites in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002591" ;
    a owl:Class ;
    rdfs:label "dendrite length reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000882 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000574
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030425
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002592
    obo:IAO_0000115 "Animals exhibit variations in their response to changes in gravitational force, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002592" ;
    a owl:Class ;
    rdfs:label "organism response to gravitational force abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000067 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0009629
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002593
    obo:IAO_0000115 "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002593" ;
    a owl:Class ;
    rdfs:label "short term plate tap habituation variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002469, obo:WBPhenotype_0002600 .

obo:WBPhenotype_0002594
    obo:IAO_0000115 "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s)." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002594" ;
    a owl:Class ;
    rdfs:label "long term plate tap habituation variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002469, obo:WBPhenotype_0002599 .

obo:WBPhenotype_0002595
    obo:IAO_0000115 "The reduction in brood size caused by sleep deprivation is enhanced, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002595" ;
    a owl:Class ;
    rdfs:label "sleep deprivation-induced brood size reduction enhanced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000154 .

obo:WBPhenotype_0002596
    obo:IAO_0000115 "The reduction in brood size caused by sleep deprivation is suppressed, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002596" ;
    a owl:Class ;
    rdfs:label "sleep deprivation-induced brood size reduction suppressed"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000154 .

obo:WBPhenotype_0002597
    obo:IAO_0000115 "Variations in the behavioral plasticity induced by the integration of two sensory signals (one of which is gustation (taste)) compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype have an abnormal response to the trained stimuli compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002597" ;
    a owl:Class ;
    rdfs:label "gustatory learning abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001780 .

obo:WBPhenotype_0002598
    obo:IAO_0000115 "Variations in the aversion of animals to substances sensed by gustation (taste) previously associated with an aversive stimuli during a gustation training protocol, compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype will not exhibit the same aversion to the substance as compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002598" ;
    a owl:Class ;
    rdfs:label "gustatory aversive learning abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002597 .

obo:WBPhenotype_0002599
    obo:IAO_0000115 "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s)." ;
    oboInOwl:hasExactSynonym "long-term habituation abnormal", "long-term habituation variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002599" ;
    a owl:Class ;
    rdfs:label "long-term habituation phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000626 .

obo:WBPhenotype_0002600
    obo:IAO_0000115 "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." ;
    oboInOwl:hasExactSynonym "short-term habituation abnormal", "short-term habituation variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002600" ;
    a owl:Class ;
    rdfs:label "short-term habituation phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000626 .

obo:WBPhenotype_0002601
    obo:IAO_0000115 "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the short term, compared to controls. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." ;
    oboInOwl:hasExactSynonym "short-term associative memory abnormal", "short-term associative memory variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002601" ;
    a owl:Class ;
    rdfs:label "short-term associative memory phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002564 .

obo:WBPhenotype_0002602
    obo:IAO_0000115 "Animals exhibit a decrease in the rate at which spontaneous backward locomotion is initiated compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002602" ;
    a owl:Class ;
    rdfs:label "reduced frequency of spontaneous reversal initiation"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001506 .

obo:WBPhenotype_0002603
    obo:IAO_0000115 "Animals exhibit an abnormal response to toxic proteins, either via exposure in the environment or expressed within the organism, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002603" ;
    a owl:Class ;
    rdfs:label "protein toxicity response abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0002604
    obo:IAO_0000115 "Animals exhibit an abnormal response to toxic dipeptide repeat proteins, either via exposure in the environment or expressed within the organism, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002604" ;
    a owl:Class ;
    rdfs:label "dipeptide repeat protein toxicity abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002603 .

obo:WBPhenotype_0002605
    obo:IAO_0000115 "Normally toxic dipeptide repeat proteins appear to be less toxic to animals, compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002605" ;
    a owl:Class ;
    rdfs:label "dipeptide repeat protein toxicity suppressed"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002604 .

obo:WBPhenotype_0002606
    obo:IAO_0000115 "Animals exhibit reduced necrotic cell death, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002606" ;
    a owl:Class ;
    rdfs:label "necrotic cell death decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000415 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002052
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0070265
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002607
    obo:IAO_0000115 "One or more cellular nuclei exhibit an abnormal size, compared to controls." ;
    oboInOwl:hasExactSynonym "nuclear size phenotype", "nuclear size variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002607" ;
    a owl:Class ;
    rdfs:label "nuclear size abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001028 .

obo:WBPhenotype_0002608
    obo:IAO_0000115 "A body elongation defect in which embryos develop abnormally bulged dorsal surfaces." ;
    oboInOwl:hasExactSynonym "Hmp" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002608" ;
    a owl:Class ;
    rdfs:comment "\"After standard ethylmethane sulfonate mutagenesis, we screened directly for mutant embryos that are defective in body elongation. We isolated 13 recessive, zygotic-lethal mutants that, in addition to failing to elongate properly, show abnormally bulged dorsal surfaces (Fig. 1B). We call this novel phenotype Hmp (humpback); this phenotype contrasts with previously described elongation-defective Pat mutants that display bulges at variable positions (Williams and Waterston, 1994).\"" ;
    rdfs:label "humpback"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000242, obo:WBPhenotype_0001136 .

obo:WBPhenotype_0002609
    obo:IAO_0000115 "An anterior enclosure defect in which the anterior portion of the embryo, unenclosed by the hypodermis, bulges to form a hammerhead shape." ;
    oboInOwl:hasExactSynonym "Hmr" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    a owl:Class ;
    rdfs:comment "\"However, in the remaining hmr-1 mutants the hypodermis fails to fully enclose the embryo. We call this phenotype Hmr (hammerhead; see Fig. 1F).\"" ;
    rdfs:label "hammerhead"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002571 .

obo:WBPhenotype_0002610
    obo:IAO_0000115 "Apoptosis occurs in cells or cell types that do not undergo apoptosis in controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002610" ;
    a owl:Class ;
    rdfs:label "ectopic apoptosis"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBPhenotype_0002611
    obo:IAO_0000115 "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is impaired." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002611" ;
    a owl:Class ;
    rdfs:label "meiotic cytoplasmic streaming defective"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000360, obo:WBPhenotype_0002613 .

obo:WBPhenotype_0002612
    obo:IAO_0000115 "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is abnormal compared to control." ;
    oboInOwl:hasExactSynonym "cytoplasmic streaming abnormal", "cytoplasmic streaming variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002612" ;
    a owl:Class ;
    rdfs:label "cytoplasmic streaming phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0099636
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002613
    obo:IAO_0000115 "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is abnormal compared to control." ;
    oboInOwl:hasExactSynonym "meiotic cytoplasmic streaming abnormal", "meiotic cytoplasmic streaming variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002613" ;
    a owl:Class ;
    rdfs:label "meiotic cytoplasmic streaming phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002612 .

obo:WBPhenotype_0002614
    obo:IAO_0000115 "Genes normally silenced within heterochromatin are abnoramally de-repressed and exhibit expression, unlike controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002614" ;
    a owl:Class ;
    rdfs:label "derepression of heterchromatic gene silencing"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000135 .

obo:WBPhenotype_0002615
    obo:IAO_0000115 "Animals accumulate vacuoles in an abnormal manner in cells, tissues, and/or organs of the animal." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002615" ;
    a owl:Class ;
    rdfs:label "abnormal accumulation of vacuoles"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000535 .

obo:WBPhenotype_0002616
    obo:IAO_0000115 "Cells exhibit an abnormal intracellular level (amount) of calcium, compared to controls." ;
    oboInOwl:hasExactSynonym "cellular calcium level phenotype", "cellular calcium level variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002616" ;
    a owl:Class ;
    rdfs:label "cellular calcium level abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000536 .

obo:WBPhenotype_0002617
    obo:IAO_0000115 "Cells exhibit a higher level of calcium in the cytosol, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002617" ;
    a owl:Class ;
    rdfs:label "cytosolic calcium levels increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002616 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000470
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:CHEBI_29108
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000050 ;
                                owl:someValuesFrom obo:GO_0005829
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002618
    obo:IAO_0000115 "Cells exhibit a lower level of calcium in the cytosol, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002618" ;
    a owl:Class ;
    rdfs:label "cytosolic calcium levels decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002616 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom [
                        a owl:Class ;
                        owl:intersectionOf (obo:CHEBI_29108
                            [
                                a owl:Restriction ;
                                owl:onProperty obo:BFO_0000050 ;
                                owl:someValuesFrom obo:GO_0005829
                            ]
                        )
                    ]
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002619
    obo:IAO_0000115 "Animals exhibit increased occurrence of cell death, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002619" ;
    a owl:Class ;
    rdfs:label "cell death increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000729 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008219
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002620
    obo:IAO_0000115 "Animals exhibit decreased occurrence of cell death, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002620" ;
    a owl:Class ;
    rdfs:label "cell death decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000729 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0002052
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0008219
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002621
    obo:IAO_0000115 "Animals exhibit a decrease in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002621" ;
    a owl:Class ;
    rdfs:label "antimicrobial gene expression reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002534 .

obo:WBPhenotype_0002622
    obo:IAO_0000115 "Animals exhibit decreased recruitment of actin to a site of injury, compared to controls." ;
    oboInOwl:hasExactSynonym "decreased recruitment of actin upon injury" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002622" ;
    a owl:Class ;
    rdfs:label "decreased recruitment of actin upon wounding"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001346, obo:WBPhenotype_0001840 .

obo:WBPhenotype_0002623
    obo:IAO_0000115 "Animals exhibit no induction of expression of an antimicrobial peptide after an injury, unlike control animals." ;
    oboInOwl:hasExactSynonym "no induction of antimicrobial peptide expression after wounding" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002623" ;
    a owl:Class ;
    rdfs:label "no induction of antimicrobial peptide expression after injury"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001840, obo:WBPhenotype_0002621 .

obo:WBPhenotype_0002624
    obo:IAO_0000115 "Cells display reduced incorporation of the thymidine analogue 5-Ethynyl-2'-deoxyuridine (EdU), suggesting reduced cell proliferation. Incorporation of EdU is an indication of active DNA synthesis and thus an indication of cells proceeding through the cell cycle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002624" ;
    a owl:Class ;
    rdfs:label "EdU incorporation reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000173 .

obo:WBPhenotype_0002625
    obo:IAO_0000115 "Animals exhibit visible, structural degeneration of the head, unlike control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002625" ;
    a owl:Class ;
    rdfs:label "head degeneration"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000532 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000639
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005739
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002626
    obo:IAO_0000115 "Animals exhibit an abnormal attachment (or lack thereof) to a substrate, compared to controls. For some parasitic worms, attachment to host tissue surfaces, like endothelium, is a necessary behavior for their life cycle." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002626" ;
    a owl:Class ;
    rdfs:label "attachment to substrate abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000576 .

obo:WBPhenotype_0002627
    obo:IAO_0000115 "Animals exhibit an abnormal attachment (or lack thereof) to a substrate in vitro, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002627" ;
    a owl:Class ;
    rdfs:label "in vitro attachment to substrate abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002626 .

obo:WBPhenotype_0002628
    obo:IAO_0000115 "Animals exhibit a reduced attachment to a substrate in vitro, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002628" ;
    a owl:Class ;
    rdfs:label "in vitro attachment to substrate reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002627 .

obo:WBPhenotype_0002629
    obo:IAO_0000115 "Animals exhibit edema (swelling) of the intestine, compared to control animals. This swelling is distinct from distension of the intestinal lumen (swollen intestinal lumen)." ;
    oboInOwl:hasExactSynonym "intestinal oedema", "swollen intestine" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002629" ;
    a owl:Class ;
    rdfs:label "intestinal edema"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000710 .

obo:WBPhenotype_0002630
    obo:IAO_0000115 "Animals exhibit degeneration of the epithelial system (skin, integument or tegument), compared to control animals." ;
    oboInOwl:hasExactSynonym "integument degeneration", "tegument degeneration" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002630" ;
    a owl:Class ;
    rdfs:label "epithelial system degeneration"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000600 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000639
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:WBbt_0005730
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002631
    obo:IAO_0000115 "Animals exhibit edema (swelling) of one or more tissues, compared to control animals." ;
    oboInOwl:hasExactSynonym "tissue oedema", "tissue swelling" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002631" ;
    a owl:Class ;
    rdfs:label "tissue edema"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000520, obo:WBPhenotype_0002556 .

obo:WBPhenotype_0002632
    obo:IAO_0000115 "Animals exhibit cells with an abnormal degree of chromatin accessibility, compared to controls, detected using techniques such as ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing)." ;
    oboInOwl:hasExactSynonym "chromatin accessibility phenotype", "chromatin accessibility variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002632" ;
    a owl:Class ;
    rdfs:label "chromatin accessibility abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001348 .

obo:WBPhenotype_0002633
    obo:IAO_0000115 "Animals exhibit a pharynx that recedes into the animal's interior such that the animal cannot feed." ;
    oboInOwl:hasExactSynonym "Pin" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002633" ;
    a owl:Class ;
    rdfs:label "pharynx ingressed"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001748 .

obo:WBPhenotype_0002634
    obo:IAO_0000115 "Animals exhibit a resistance to endoplasmic reticulum (ER) stressors such as an accumulation of unfolded proteins or the presence of chemicals that induce ER stress, such as dithiothreitol (DDT) or tunicamycin, compared to controls. This may mean that animals fare better than controls in terms of survival or some metric of health when exposed to an inducer of ER stress." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002634" ;
    a owl:Class ;
    rdfs:label "ER stress resistant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001485 .

obo:WBPhenotype_0002635
    obo:IAO_0000115 "Animals shed fragments of epidermis into the surrounding environment, unlike controls. In embryos, these fragments can be seen in the extra-embryonic space." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002635" ;
    a owl:Class ;
    rdfs:label "epidermal shedding"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000619 .

obo:WBPhenotype_0002636
    obo:IAO_0000115 "One or more cells of the animal exhibit chromatin that has become detached from the nuclear periphery, unlike controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002636" ;
    a owl:Class ;
    rdfs:label "detachment of chromatin from nuclear periphery"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002542 .

obo:WBPhenotype_0002637
    obo:IAO_0000115 "Animals (or cells of the animal) exhibit reduced levels of iron in the body (or cells) compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002637" ;
    a owl:Class ;
    rdfs:label "iron levels decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002046 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CHEBI_18248
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002638
    obo:IAO_0000115 "Animals are more prone to infection, sickness and/or death caused by oomycete pathogens compared to control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002638" ;
    a owl:Class ;
    rdfs:label "increased susceptibility to oomycete infection"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001013 .

obo:WBPhenotype_0002639
    obo:IAO_0000115 "Animals exhibit specific or general variations in the composition of the microbiome at a body site compared to controls." ;
    oboInOwl:hasExactSynonym "microbiome composition variant" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002639" ;
    a owl:Class ;
    rdfs:label "microbiome composition abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0002640
    obo:IAO_0000115 "The physical strength or integrity of the cuticle is decreased compared to that observed for control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002640" ;
    a owl:Class ;
    rdfs:label "cuticle integrity decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001211 .

obo:WBPhenotype_0002641
    obo:IAO_0000115 "The cuticle of animals becomes more permeable to dyes or stains, such as Hoechst 33258, or other substances compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002641" ;
    a owl:Class ;
    rdfs:label "cuticle permeability increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002640 .

obo:WBPhenotype_0002642
    obo:IAO_0000115 "Animals exposed to an exogenous chemical exhibit an abnormal accumulation of this chemical in the body of the animals, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002642" ;
    a owl:Class ;
    rdfs:label "chemical accumulation abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000523 .

obo:WBPhenotype_0002643
    obo:IAO_0000115 "Animals exposed to an exogenous chemical exhibit an abnormal increase in accumulation of this chemical in the body of the animals, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002643" ;
    a owl:Class ;
    rdfs:label "chemical accumulation increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002642 .

obo:WBPhenotype_0002644
    obo:IAO_0000115 "Animals do not respond to the edge or gap in the medium surface they were supported on in the same manner as controls. In Mitchell et al., the precipice response was defined to be that within 2 seconds of the nose moving off the edge of the agar chunk, the worm begins a reversal that completes at least one full sine wave." ;
    oboInOwl:hasExactSynonym "precipice response abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002644" ;
    a owl:Class ;
    rdfs:label "precipice response variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0002645
    obo:IAO_0000115 "Animals exhibit an abnormal recovery from heat stress, compared to controls." ;
    oboInOwl:hasExactSynonym "heat stress recovery abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002645" ;
    a owl:Class ;
    rdfs:comment "Exposure of wild type worms to a 6 h heat shock at 33°C led to a 20% decrease in worms with normal movement after a 48 h recovery at 20°C." ;
    rdfs:label "thermorecovery abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000146 .

obo:WBPhenotype_0002646
    obo:IAO_0000115 "Animals exhibit reduced recovery from heat stress compared to controls. Reduced recovery may be indicated, for example, by a decrease in normal movement, such as uncoordinated or jerky movement or paralysis, compared to controls." ;
    oboInOwl:hasExactSynonym "heat stress recovery reduced" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002646" ;
    a owl:Class ;
    rdfs:label "thermorecovery reduced"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002645 .

obo:WBPhenotype_0002647
    obo:IAO_0000115 "Animals display variations in the structure, organization of components, or spatial pattern of the neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002647" ;
    a owl:Class ;
    rdfs:label "dendrite morphology variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001398 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000051
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0030425
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002648
    obo:IAO_0000115 "Animals display variations in the number or pattern of neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002648" ;
    a owl:Class ;
    rdfs:label "dendrite branching variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002647 .

obo:WBPhenotype_0002649
    obo:IAO_0000115 "Characteristic response to chemicals with respect to egg-laying behavior varies compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002649" ;
    a owl:Class ;
    rdfs:label "egg laying response to chemical abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000523 .

obo:WBPhenotype_0002650
    obo:IAO_0000115 "Characteristic response to extracted lipopolysaccharide from pathogens with respect to egg-laying behavior varies compared to control conditions." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002650" ;
    a owl:Class ;
    rdfs:label "egg laying response to pathogen lipopolysaccharide variant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002649 .

obo:WBPhenotype_0002651
    obo:IAO_0000115 "Cells exhibit an abnormal production of exophers, large (approximately four microns in diameter) membrane-bound extracellular vesicles that are released by budding out of cells into the extracellular space, compared to controls." ;
    oboInOwl:hasExactSynonym "exopher production abnormal", "exopher-genesis abnormal", "exopher-genesis phenotype" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002651" ;
    a owl:Class ;
    rdfs:label "exopher production phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000258 .

obo:WBPhenotype_0002652
    obo:IAO_0000115 "Cells exhibit a increase in production of exophers compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002652" ;
    a owl:Class ;
    rdfs:label "exopher production increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002651 .

obo:WBPhenotype_0002653
    obo:IAO_0000115 "Cells exhibit a decrease in production of exophers compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002653" ;
    a owl:Class ;
    rdfs:label "exopher production decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002651 .

obo:WBPhenotype_0002654
    obo:IAO_0000115 "Muscle cells exhibit an abnormal production of exophers compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002654" ;
    a owl:Class ;
    rdfs:label "exopher production in muscle phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000990, obo:WBPhenotype_0002651 .

obo:WBPhenotype_0002655
    obo:IAO_0000115 "Muscle cells exhibit a decrease in production of exophers compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002655" ;
    a owl:Class ;
    rdfs:label "exopher production in muscle decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002653, obo:WBPhenotype_0002654 .

obo:WBPhenotype_0002656
    obo:IAO_0000115 "Muscle cells exhibit an increase in production of exophers compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002656" ;
    a owl:Class ;
    rdfs:label "exopher production in muscle increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002652, obo:WBPhenotype_0002654 .

obo:WBPhenotype_0002657
    obo:IAO_0000115 "Animals exhibit intolerance (e.g. lethality or significant growth defect) when exposed to saturated fatty acids via the diet, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002657" ;
    a owl:Class ;
    rdfs:label "dietary saturated fatty acid intolerant"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001072, obo:WBPhenotype_0001918 .

obo:WBPhenotype_0002658
    obo:IAO_0000115 "Animals exhibit variations in muscle strength, as measured by a strength determining assay, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002658" ;
    a owl:Class ;
    rdfs:label "muscle strength phenotype"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000611 .

obo:WBPhenotype_0002659
    obo:IAO_0000115 "Animals exhibit a decrease in muscle strength, as measured by a strength determining assay, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002659" ;
    a owl:Class ;
    rdfs:label "muscle strength decreased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0002658 .

obo:WBPhenotype_0002660
    obo:IAO_0000115 "Animals exhibit a depletion of germline stem cells, compared to controls." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002660" ;
    a owl:Class ;
    rdfs:label "germline stem cell depletion"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000684 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001997
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:CL_0000086
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0002661
    obo:IAO_0000115 "Genes, whose expression is typically induced by an innate immune response, are actively expressed under conditions which would not normally induce an innate immune response gene expression program." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002661" ;
    a owl:Class ;
    rdfs:label "constitutive expression of innate immune response genes"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000135 .

obo:WBPhenotype_0002662
    obo:IAO_0000115 "Animals exhibit an increase in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002662" ;
    a owl:Class ;
    rdfs:label "transgene silencing increased"@en ;
    rdfs:subClassOf obo:WBPhenotype_0001593 .

obo:WBPhenotype_0002663
    obo:IAO_0000115 "Cells of the animal exhibit variations in the intracellular lipid surveillance response, responsible for responding to and addressing lipid depletion inside of cells, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0002663" ;
    a owl:Class ;
    rdfs:label "intracellular lipid surveillance response abnormal"@en ;
    rdfs:subClassOf obo:WBPhenotype_0000577 .

obo:WBPhenotype_0004001
    obo:IAO_0000115 "Any variation in the specific actions or reactions of a hermaphrodite during mating compared to control." ;
    oboInOwl:hasNarrowSynonym "hermaphrodite mating abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004001" ;
    a owl:Class ;
    rdfs:label "hermaphrodite mating variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000647, obo:WBPhenotype_0000887 .

obo:WBPhenotype_0004002
    obo:IAO_0000115 "Animals exhibit defects in the production of the sensory signal to attract males." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004002" ;
    a owl:Class ;
    rdfs:label "attraction signal defective" ;
    rdfs:subClassOf obo:WBPhenotype_0004015 .

obo:WBPhenotype_0004003
    obo:IAO_0000115 "Males exhibit defects in their response to the mate-finding cue." ;
    oboInOwl:hasNarrowSynonym "mate finding abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "response to male attractant abnormal" ;
    oboInOwl:id "WBPhenotype:0004003" ;
    a owl:Class ;
    rdfs:label "mate finding defective" ;
    rdfs:subClassOf obo:WBPhenotype_0004005 .

obo:WBPhenotype_0004004
    obo:IAO_0000115 "The inability of a male to respond properly to a potential mate after contact. In C.elegans, proper response includes apposing the ventral side of his tail to the hermaphrodite's body and swimming backward." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004004" ;
    a owl:Class ;
    rdfs:label "male response to contact defective" ;
    rdfs:subClassOf obo:WBPhenotype_0001414, obo:WBPhenotype_0004006, obo:WBPhenotype_0004030 .

obo:WBPhenotype_0004005
    obo:IAO_0000115 "Males exhibit variations in mating behavior prior to contacting its mate compared to control." ;
    oboInOwl:hasNarrowSynonym "pre hermaphrodite contact abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004005" ;
    a owl:Class ;
    rdfs:label "pre hermaphrodite contact variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000648 .

obo:WBPhenotype_0004006
    obo:IAO_0000115 "Males exhibit variations in mating behavior after contacting its mate compared to control." ;
    oboInOwl:hasNarrowSynonym "post hermaphrodite contact abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004006" ;
    a owl:Class ;
    rdfs:label "post hermaphrodite contact variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000648 .

obo:WBPhenotype_0004007
    obo:IAO_0000115 "Males exhibit defects in the continuous prodding of spicule tips at the vulva prior to prolonged spicule insertion." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "spicule prodding defective" ;
    oboInOwl:id "WBPhenotype:0004007" ;
    a owl:Class ;
    rdfs:label "periodic spicule prodding defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000279 .

obo:WBPhenotype_0004008
    obo:IAO_0000115 "Males exhibit defects in the prolonged, tonic, spicule extrusion through the vulva prior to sperm transfer." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "prolonged spicule protraction defective" ;
    oboInOwl:id "WBPhenotype:0004008" ;
    a owl:Class ;
    rdfs:label "sustained spicule protraction defective" ;
    rdfs:subClassOf obo:WBPhenotype_0002443 .

obo:WBPhenotype_0004009
    obo:IAO_0000115 "Any variation in the mating process that includes the male stopping at the vulva (usually after backing) compared to control. In C. elegans general vulva location (stopping) requires the hook sensillum." ;
    oboInOwl:hasNarrowSynonym "approximate vulval location abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "approximate vulva location variant", "general vulval location abnormal" ;
    oboInOwl:id "WBPhenotype:0004009" ;
    a owl:Class ;
    rdfs:label "approximate vulval location variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000649 .

obo:WBPhenotype_0004010
    obo:IAO_0000115 "Any variation in the mating process that includes the male positioning his tail precisely over the vulva so that he may insert his spicules and ejaculate compared to control. In C. elegans precise vulva location (coordinating movement and tail positioning) requires the post cloacal sensillium and the spicules." ;
    oboInOwl:hasNarrowSynonym "precise vulval location abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:hasRelatedSynonym "precise vulva location variant" ;
    oboInOwl:id "WBPhenotype:0004010" ;
    a owl:Class ;
    rdfs:label "precise vulval location variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000649 .

obo:WBPhenotype_0004011
    obo:IAO_0000115 "Any variation in the retraction of spicules after all sperm that exit the seminal vesicle have been released compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004011" ;
    a owl:Class ;
    rdfs:label "sperm transfer cessation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000284 .

obo:WBPhenotype_0004012
    obo:IAO_0000115 "Any variation in the continued movement of sperm through the vas deferens, exiting the cloaca, compared to control. In C. elegans, when all sperm that exit the seminal vesicle have been released, the spicules retract into the male." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004012" ;
    a owl:Class ;
    rdfs:label "sperm transfer continuation defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000284 .

obo:WBPhenotype_0004013
    obo:IAO_0000115 "Any variation in the initial movement of sperm through the vas deferens, exiting the cloaca, compared to control." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004013" ;
    a owl:Class ;
    rdfs:label "sperm release defective" ;
    rdfs:subClassOf obo:WBPhenotype_0000284 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001511
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0042713
                ]
            )
        ]
    ] .

obo:WBPhenotype_0004014
    obo:IAO_0000115 "Any variation in the specific actions or reactions of a hermaphrodite after male contact during mating compared to control." ;
    oboInOwl:hasNarrowSynonym "post male contact abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004014" ;
    a owl:Class ;
    rdfs:label "post male contact variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004001 .

obo:WBPhenotype_0004015
    obo:IAO_0000115 "Any variation in the specific actions or reactions of a hermaphrodite prior to male contact during mating compared to control." ;
    oboInOwl:hasNarrowSynonym "pre male contact abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004015" ;
    a owl:Class ;
    rdfs:label "pre male contact variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004001 .

obo:WBPhenotype_0004016
    obo:IAO_0000115 "Any variation in the behavior exhibited by dauer larva in which they crawl up upon the substrate and wave back and forth while standing on their tail compared to control. Nictation is often associated with the search for a new host." ;
    oboInOwl:hasNarrowSynonym "dauer nictation behavior abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004016" ;
    a owl:Class ;
    rdfs:label "dauer nictation behavior variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001001 .

obo:WBPhenotype_0004017
    obo:IAO_0000115 "Animals exhibit variations in their ability to maintain characteristic and effective locomotion compared to control." ;
    oboInOwl:hasNarrowSynonym "locomotor coordination abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004017" ;
    a owl:Class ;
    rdfs:label "locomotor coordination variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000643 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000188
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040011
                ]
            )
        ]
    ] .

obo:WBPhenotype_0004018
    obo:IAO_0000115 "Any variation in the propagation of the contraction sine wave along the body while an animal travels from one location to another, compared to control." ;
    oboInOwl:hasNarrowSynonym "sinusoidal movement abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004018" ;
    a owl:Class ;
    rdfs:label "sinusoidal movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004017 .

obo:WBPhenotype_0004021
    obo:IAO_0000115 "OBSOLETE." ;
    obo:IAO_0100001 obo:WBPhenotype_0000664 ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004021" ;
    a owl:Class ;
    rdfs:label "obsolete exaggerated body bends" ;
    owl:deprecated true .

obo:WBPhenotype_0004022
    obo:IAO_0000115 "Any variation in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." ;
    oboInOwl:hasExactSynonym "amplitude of body bends variant" ;
    oboInOwl:hasNarrowSynonym "amplitude of movement abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004022" ;
    a owl:Class ;
    rdfs:label "amplitude of sinusoidal movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001703 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000080
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040011
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0004023
    obo:IAO_0000115 "Animals exhibit variations in the frequency of oscillations between adjacent body segments from that observed for control animals." ;
    oboInOwl:hasAlternativeId "WBPhenotype:0002329" ;
    oboInOwl:hasExactSynonym "frequency of sinusoidal movement variant", "temporal frequency of sinusoidal movement variant" ;
    oboInOwl:hasNarrowSynonym "bending frequency abnormal", "frequency of body bend abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004023" ;
    a owl:Class ;
    rdfs:label "frequency of body bend variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001703 .

obo:WBPhenotype_0004024
    obo:IAO_0000115 "Any variation in the distance in the line of advance of a body wave from any one point to the next point of corresponding phase compared to control." ;
    oboInOwl:hasNarrowSynonym "wavelength of movement abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004024" ;
    a owl:Class ;
    rdfs:label "wavelength of movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004018 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001242
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040011
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0004025
    obo:IAO_0000115 "Animals exhibit variations in the net velocity of an animal, that is, the maximum distance an animal traverses over an extended period of time, from that observed for control animals." ;
    oboInOwl:hasNarrowSynonym "velocity of movement abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004025" ;
    a owl:Class ;
    rdfs:label "velocity of movement variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000641 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0000008
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0040011
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0004026
    obo:IAO_0000115 "Variations in the ability of an animal to respond with characteristic backward movement after a nose-on collision with an object compared to control. In C. elegans, this phenotype is usually assayed via stroking with a hair or similar fiber on the anterior most tip of the animal." ;
    oboInOwl:hasNarrowSynonym "nose touch abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004026" ;
    a owl:Class ;
    rdfs:label "nose touch variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0004027
    obo:IAO_0000115 "Animals exhibit variations in their response to substrate vibration compared to control." ;
    oboInOwl:hasNarrowSynonym "plate tap reflex abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004027" ;
    a owl:Class ;
    rdfs:label "plate tap reflex variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0004028
    obo:IAO_0000115 "Animals exhibit variations in modulating their locomotory rate in response to its food , compared to control. Basal slowing response refers to when well-fed animals move more slowly in the presence of bacteria than in the absence of bacteria . Second , food-deprived control animals , when transferred to bacteria , display a dramatically enhanced slowing response that ensures that the animals do not leave their newly encountered source of food." ;
    oboInOwl:hasNarrowSynonym "slowing response on food abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004028" ;
    a owl:Class ;
    rdfs:label "slowing response on food variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0004029
    obo:IAO_0000115 "Any variation with respect to perception or response to mechanical stimuli in a sex dependent manner compared to control animals." ;
    oboInOwl:hasNarrowSynonym "sexually dimorphic mechanosensation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004029" ;
    a owl:Class ;
    rdfs:label "sexually dimorphic mechanosensation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000315 .

obo:WBPhenotype_0004030
    obo:IAO_0000115 "Any variation in the response by the male to a hermaphrodite after initial contact following mate finding compared to control. In C. elegans the male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate." ;
    oboInOwl:hasBroadSynonym "Rsp" ;
    oboInOwl:hasNarrowSynonym "male response to hermaphrodite abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004030" ;
    a owl:Class ;
    rdfs:label "male response to hermaphrodite variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004029 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0034606
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0004031
    obo:IAO_0000115 "Any variation in the ability of an animal to search for a mate compared to control. In C. elegans, this is defined by failure of the leaving assay." ;
    oboInOwl:hasNarrowSynonym "mate searching abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0004031" ;
    a owl:Class ;
    rdfs:label "mate searching variant" ;
    rdfs:subClassOf obo:WBPhenotype_0004005 .

obo:WBPhenotype_0006001
    obo:IAO_0000115 "The apparent partial collapse of the vulval invagination and the elongation of central vulva cells often leading to a flattened appearance." ;
    oboInOwl:hasBroadSynonym "Sqv" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0006001" ;
    a owl:Class ;
    rdfs:label "squashed vulva" ;
    rdfs:subClassOf obo:WBPhenotype_0000510 .

obo:WBPhenotype_0008001
    obo:IAO_0000115 "Any variation in the processes that govern acquisition of particular cell fates in the embryo, from the time of zygote formation until hatching compared to control." ;
    oboInOwl:hasNarrowSynonym "embryonic cell fate specification abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0008001" ;
    a owl:Class ;
    rdfs:label "embryonic cell fate specification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000216, obo:WBPhenotype_0000749 .

obo:WBPhenotype_0008002
    obo:IAO_0000115 "Any variation in the processes that govern acquisition of somatic cell fates in the embryo, from the time of zygote formation until hatching compared to control." ;
    oboInOwl:hasNarrowSynonym "embryonic somatic cell fate specification abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0008002" ;
    a owl:Class ;
    rdfs:label "embryonic somatic cell fate specification variant" ;
    rdfs:subClassOf obo:WBPhenotype_0008001 .

obo:WBPhenotype_0008003
    obo:IAO_0000115 "Any variation in a learned olfactory response whereby exposure of animals to odorants during specific developmental times or physiological states results in a lasting memory compared to control. In control animals, this imprinting determines the animal's behavior upon encountering the same odorant at a later time." ;
    oboInOwl:hasExactSynonym "olfactory imprinting abnormal" ;
    oboInOwl:hasNarrowSynonym "odorant imprinting abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0008003" ;
    a owl:Class ;
    rdfs:label "odorant imprinting variant" ;
    rdfs:subClassOf obo:WBPhenotype_0001048 .

obo:WBPhenotype_0010001
    obo:IAO_0000115 "Variations in the process(es) by which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter compared to control." ;
    oboInOwl:hasNarrowSynonym "cell growth abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0010001" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell growth variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000536 ;
    owl:equivalentClass [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Class ;
            owl:intersectionOf (obo:PATO_0001236
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0000052 ;
                    owl:someValuesFrom obo:GO_0016049
                ]
                [
                    a owl:Restriction ;
                    owl:onProperty obo:RO_0002573 ;
                    owl:someValuesFrom obo:PATO_0000460
                ]
            )
        ]
    ] .

obo:WBPhenotype_0010002
    obo:IAO_0000115 "Variations in the process(es) involved in the assembly and arrangement of cell structures compared to control." ;
    oboInOwl:hasNarrowSynonym "cell organization biogenesis abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0010002" ;
    oboInOwl:inSubset wbphenotype:phenotype_slim_wb ;
    a owl:Class ;
    rdfs:label "cell organization biogenesis variant" ;
    rdfs:subClassOf obo:WBPhenotype_0002089 .

obo:WBPhenotype_0010003
    obo:IAO_0000115 "Animals exhibit a decreased rate programmed cell death pathway leading to the destruction of the cell, viewable in its terminally dismanteled form of a cell corpse, compared to that observed for control cells." ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0010003" ;
    a owl:Class ;
    rdfs:label "cell corpse appearance delayed" ;
    rdfs:subClassOf obo:WBPhenotype_0000185, obo:WBPhenotype_0000438 .

obo:WBPhenotype_0010004
    obo:IAO_0000115 "Variations in the process(es) that constitute cell corpse degradation within the engulfing cell compared to control." ;
    oboInOwl:hasDbXref "WB:rk" ;
    oboInOwl:hasNarrowSynonym "cell corpse degradation abnormal" ;
    oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ;
    oboInOwl:id "WBPhenotype:0010004" ;
    a owl:Class ;
    rdfs:label "cell corpse degradation variant" ;
    rdfs:subClassOf obo:WBPhenotype_0000730 .

obo:WBbt_0000100
    a owl:Class .

obo:WBbt_0000101
    a owl:Class .

obo:WBbt_0003670
    a owl:Class .

obo:WBbt_0003672
    a owl:Class .

obo:WBbt_0003673
    a owl:Class .

obo:WBbt_0003675
    a owl:Class .

obo:WBbt_0003679
    a owl:Class .

obo:WBbt_0003681
    a owl:Class .

obo:WBbt_0003711
    a owl:Class .

obo:WBbt_0003732
    a owl:Class .

obo:WBbt_0003733
    a owl:Class .

obo:WBbt_0003734
    a owl:Class .

obo:WBbt_0003760
    a owl:Class ;
    rdfs:subClassOf [
        a owl:Restriction ;
        owl:onProperty obo:BFO_0000051 ;
        owl:someValuesFrom [
            a owl:Restriction ;
            owl:onProperty obo:RO_0000052 ;
            owl:someValuesFrom obo:UBERON_0000062
        ]
    ] .

obo:WBbt_0003810
    a owl:Class .

obo:WBbt_0003825
    a owl:Class .

obo:WBbt_0004015
    a owl:Class .

obo:WBbt_0004017
    a owl:Class .

obo:WBbt_0004112
    a owl:Class .

obo:WBbt_0004216
    a owl:Class .

obo:WBbt_0004421
    a owl:Class .

obo:WBbt_0004422
    a owl:Class .

obo:WBbt_0004432
    a owl:Class .

obo:WBbt_0004458
    a owl:Class .

obo:WBbt_0004489
    a owl:Class .

obo:WBbt_0004499
    a owl:Class .

obo:WBbt_0004522
    a owl:Class .

obo:WBbt_0004534
    a owl:Class .

obo:WBbt_0004540
    a owl:Class .

obo:WBbt_0004578
    a owl:Class .

obo:WBbt_0004583
    a owl:Class .

obo:WBbt_0004778
    a owl:Class .

obo:WBbt_0004780
    a owl:Class .

obo:WBbt_0004799
    a owl:Class .

obo:WBbt_0004804
    a owl:Class .

obo:WBbt_0004873
    a owl:Class .

obo:WBbt_0004942
    a owl:Class .

obo:WBbt_0004946
    a owl:Class .

obo:WBbt_0005022
    a owl:Class .

obo:WBbt_0005024
    a owl:Class .

obo:WBbt_0005062
    a owl:Class .

obo:WBbt_0005105
    a owl:Class .

obo:WBbt_0005107
    a owl:Class .

obo:WBbt_0005116
    a owl:Class .

obo:WBbt_0005175
    a owl:Class .

obo:WBbt_0005176
    a owl:Class .

obo:WBbt_0005189
    a owl:Class .

obo:WBbt_0005208
    a owl:Class .

obo:WBbt_0005212
    a owl:Class .

obo:WBbt_0005214
    a owl:Class .

obo:WBbt_0005237
    a owl:Class .

obo:WBbt_0005255
    a owl:Class .

obo:WBbt_0005298
    a owl:Class .

obo:WBbt_0005312
    a owl:Class .

obo:WBbt_0005319
    a owl:Class .

obo:WBbt_0005342
    a owl:Class .

obo:WBbt_0005364
    a owl:Class .

obo:WBbt_0005375
    a owl:Class .

obo:WBbt_0005391
    a owl:Class .

obo:WBbt_0005394
    a owl:Class .

obo:WBbt_0005409
    a owl:Class .

obo:WBbt_0005425
    a owl:Class .

obo:WBbt_0005440
    a owl:Class .

obo:WBbt_0005448
    a owl:Class .

obo:WBbt_0005451
    a owl:Class .

obo:WBbt_0005460
    a owl:Class .

obo:WBbt_0005465
    a owl:Class .

obo:WBbt_0005501
    a owl:Class .

obo:WBbt_0005656
    a owl:Class .

obo:WBbt_0005671
    a owl:Class .

obo:WBbt_0005729
    a owl:Class .

obo:WBbt_0005730
    a owl:Class .

obo:WBbt_0005732
    a owl:Class .

obo:WBbt_0005733
    a owl:Class .

obo:WBbt_0005735
    a owl:Class .

obo:WBbt_0005736
    a owl:Class .

obo:WBbt_0005737
    a owl:Class .

obo:WBbt_0005738
    a owl:Class .

obo:WBbt_0005739
    a owl:Class .

obo:WBbt_0005740
    a owl:Class .

obo:WBbt_0005741
    a owl:Class .

obo:WBbt_0005745
    a owl:Class .

obo:WBbt_0005746
    a owl:Class .

obo:WBbt_0005747
    a owl:Class .

obo:WBbt_0005748
    a owl:Class .

obo:WBbt_0005749
    a owl:Class .

obo:WBbt_0005750
    a owl:Class .

obo:WBbt_0005751
    a owl:Class .

obo:WBbt_0005752
    a owl:Class .

obo:WBbt_0005753
    a owl:Class .

obo:WBbt_0005755
    a owl:Class .

obo:WBbt_0005756
    a owl:Class .

obo:WBbt_0005762
    a owl:Class .

obo:WBbt_0005767
    a owl:Class .

obo:WBbt_0005768
    a owl:Class .

obo:WBbt_0005772
    a owl:Class .

obo:WBbt_0005773
    a owl:Class .

obo:WBbt_0005774
    a owl:Class .

obo:WBbt_0005775
    a owl:Class .

obo:WBbt_0005776
    a owl:Class .

obo:WBbt_0005779
    a owl:Class .

obo:WBbt_0005780
    a owl:Class .

obo:WBbt_0005784
    a owl:Class .

obo:WBbt_0005785
    a owl:Class .

obo:WBbt_0005792
    a owl:Class .

obo:WBbt_0005811
    a owl:Class .

obo:WBbt_0005812
    a owl:Class .

obo:WBbt_0005813
    a owl:Class .

obo:WBbt_0005821
    a owl:Class .

obo:WBbt_0005828
    a owl:Class .

obo:WBbt_0005829
    a owl:Class .

obo:WBbt_0005830
    a owl:Class .

obo:WBbt_0005837
    a owl:Class .

obo:WBbt_0005843
    a owl:Class .

obo:WBbt_0006748
    a owl:Class .

obo:WBbt_0006749
    a owl:Class .

obo:WBbt_0006750
    a owl:Class .

obo:WBbt_0006754
    a owl:Class .

obo:WBbt_0006760
    a owl:Class .

obo:WBbt_0006761
    a owl:Class .

obo:WBbt_0006770
    a owl:Class .

obo:WBbt_0006783
    a owl:Class .

obo:WBbt_0006790
    a owl:Class .

obo:WBbt_0006794
    a owl:Class .

obo:WBbt_0006795
    a owl:Class .

obo:WBbt_0006796
    a owl:Class .

obo:WBbt_0006797
    a owl:Class .

obo:WBbt_0006798
    a owl:Class .

obo:WBbt_0006799
    a owl:Class .

obo:WBbt_0006804
    a owl:Class .

obo:WBbt_0006816
    a owl:Class .

obo:WBbt_0006830
    a owl:Class .

obo:WBbt_0006849
    a owl:Class .

obo:WBbt_0006850
    a owl:Class .

obo:WBbt_0006865
    a owl:Class .

obo:WBbt_0006908
    a owl:Class .

obo:WBbt_0006909
    a owl:Class .

obo:WBbt_0006920
    a owl:Class .

obo:WBbt_0006926
    a owl:Class .

obo:WBbt_0006929
    a owl:Class .

obo:WBbt_0006941
    a owl:Class .

obo:WBbt_0006979
    a owl:Class .

obo:WBbt_0007028
    a owl:Class .

obo:WBbt_0007809
    a owl:Class .

obo:WBbt_0007816
    a owl:Class .

obo:WBbt_0007832
    a owl:Class .

obo:WBbt_0007833
    a owl:Class .

obo:WBbt_0007846
    a owl:Class .

obo:WBbt_0007849
    a owl:Class .

obo:WBbt_0007850
    a owl:Class .

obo:WBbt_0008410
    a owl:Class .

obo:WBbt_0008424
    a owl:Class .

obo:WBbt_0008425
    a owl:Class .

obo:WBbt_0008426
    a owl:Class .

obo:WBbt_0008429
    a owl:Class .

obo:WBbt_0008439
    a owl:Class .

obo:WBbt_0008588
    a owl:Class .

obo:WBbt_0008589
    a owl:Class .

obo:WBbt_0008590
    a owl:Class .

obo:WBbt_0008593
    a owl:Class .

obo:WBbt_0008608
    a owl:Class .

obo:WBbt_0008611
    a owl:Class .

obo:WBbt_0008627
    a owl:Class .

obo:WBls_0000003
    a owl:Class .

obo:WBls_0000004
    a owl:Class .

obo:WBls_0000006
    a owl:Class .

obo:WBls_0000021
    a owl:Class .

obo:WBls_0000022
    a owl:Class .

obo:WBls_0000023
    a owl:Class .

obo:WBls_0000024
    a owl:Class .

obo:WBls_0000027
    a owl:Class .

obo:WBls_0000029
    a owl:Class .

obo:WBls_0000032
    a owl:Class .

obo:WBls_0000035
    a owl:Class .

obo:WBls_0000037
    a owl:Class .

obo:WBls_0000038
    a owl:Class .

obo:WBls_0000040
    a owl:Class .

obo:WBls_0000041
    a owl:Class .

obo:WBls_0000056
    a owl:Class .

obo:WBls_0000057
    a owl:Class .

wbphenotype:phenotype_slim_wb
    a owl:AnnotationProperty ;
    rdfs:comment "WB phenotype slim" ;
    rdfs:subPropertyOf oboInOwl:SubsetProperty .

wbphenotype:property-value
    a owl:AnnotationProperty .

<http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-base.owl>
    obo:IAO_0000700 obo:WBPhenotype_0000886 ;
    dc:description "Ontology about C. elegans and other nematode phenotypes" ;
    dc:title "C elegans Phenotype Ontology" ;
    dc:type obo:IAO_8000001 ;
    terms:license <http://creativecommons.org/licenses/by/4.0/> ;
    oboInOwl:default-namespace "C_elegans_phenotype_ontology" ;
    oboInOwl:saved-by "chris-grove" ;
    a owl:Ontology ;
    owl:versionIRI <http://purl.obolibrary.org/obo/wbphenotype/releases/2024-01-16/wbphenotype-base.owl> ;
    owl:versionInfo "2024-01-16" .

<http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#during>
    a owl:ObjectProperty .

<http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#ends_during_or_before>
    a owl:ObjectProperty .

<http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#has_quality>
    a owl:ObjectProperty .

<http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#in_response_to>
    a owl:ObjectProperty .

<http://purl.obolibrary.org/obo/wbphenotype/wbphenotype-equivalent-axioms-subq#starts_during_or_after>
    a owl:ObjectProperty .

dc:description
    a owl:AnnotationProperty .

dc:title
    a owl:AnnotationProperty .

dc:type
    a owl:AnnotationProperty .

terms:license
    a owl:AnnotationProperty .

oboInOwl:SubsetProperty
    a owl:AnnotationProperty ;
    rdfs:label "subset_property" .

oboInOwl:auto-generated-by
    a owl:AnnotationProperty .

oboInOwl:consider
    a owl:AnnotationProperty .

oboInOwl:date
    a owl:AnnotationProperty .

oboInOwl:default-namespace
    a owl:AnnotationProperty .

oboInOwl:hasAlternativeId
    a owl:AnnotationProperty ;
    rdfs:label "has_alternative_id" .

oboInOwl:hasBroadSynonym
    a owl:AnnotationProperty ;
    rdfs:label "has_broad_synonym" .

oboInOwl:hasDbXref
    a owl:AnnotationProperty ;
    rdfs:label "database_cross_reference" .

oboInOwl:hasExactSynonym
    a owl:AnnotationProperty ;
    rdfs:label "has_exact_synonym" .

oboInOwl:hasNarrowSynonym
    a owl:AnnotationProperty ;
    rdfs:label "has_narrow_synonym" .

oboInOwl:hasOBOFormatVersion
    a owl:AnnotationProperty ;
    rdfs:label "has_obo_format_version" .

oboInOwl:hasOBONamespace
    a owl:AnnotationProperty ;
    rdfs:label "has_obo_namespace" .

oboInOwl:hasRelatedSynonym
    a owl:AnnotationProperty ;
    rdfs:label "has_related_synonym" .

oboInOwl:id
    a owl:AnnotationProperty .

oboInOwl:inSubset
    a owl:AnnotationProperty ;
    rdfs:label "in_subset" .

oboInOwl:saved-by
    a owl:AnnotationProperty .

rdfs:comment
    a owl:AnnotationProperty .

rdfs:label
    a owl:AnnotationProperty .

owl:deprecated
    a owl:AnnotationProperty .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004015 ;
    owl:annotatedTarget "Any variation in the specific actions or reactions of a hermaphrodite prior to male contact during mating compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027241", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004016 ;
    owl:annotatedTarget "Any variation in the behavior exhibited by dauer larva in which they crawl up upon the substrate and wave back and forth while standing on their tail compared to control. Nictation is often associated with the search for a new host." .

[]
    oboInOwl:hasDbXref "WB:WBperson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004017 ;
    owl:annotatedTarget "Animals exhibit variations in their ability to maintain characteristic and effective locomotion compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004018 ;
    owl:annotatedTarget "Any variation in the propagation of the contraction sine wave along the body while an animal travels from one location to another, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004022 ;
    owl:annotatedTarget "Any variation in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024949", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004023 ;
    owl:annotatedTarget "Animals exhibit variations in the frequency of oscillations between adjacent body segments from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004024 ;
    owl:annotatedTarget "Any variation in the distance in the line of advance of a body wave from any one point to the next point of corresponding phase compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032008", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004025 ;
    owl:annotatedTarget "Animals exhibit variations in the net velocity of an animal, that is, the maximum distance an animal traverses over an extended period of time, from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001705", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004026 ;
    owl:annotatedTarget "Variations in the ability of an animal to respond with characteristic backward movement after a nose-on collision with an object compared to control. In C. elegans, this phenotype is usually assayed via stroking with a hair or similar fiber on the anterior most tip of the animal." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004027 ;
    owl:annotatedTarget "Animals exhibit variations in their response to substrate vibration compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004195", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004028 ;
    owl:annotatedTarget "Animals exhibit variations in modulating their locomotory rate in response to its food , compared to control. Basal slowing response refers to when well-fed animals move more slowly in the presence of bacteria than in the absence of bacteria . Second , food-deprived control animals , when transferred to bacteria , display a dramatically enhanced slowing response that ensures that the animals do not leave their newly encountered source of food." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004029 ;
    owl:annotatedTarget "Any variation with respect to perception or response to mechanical stimuli in a sex dependent manner compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0034606", "WB:WBPaper00002109", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004030 ;
    owl:annotatedTarget "Any variation in the response by the male to a hermaphrodite after initial contact following mate finding compared to control. In C. elegans the male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024428" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004031 ;
    owl:annotatedTarget "Any variation in the ability of an animal to search for a mate compared to control. In C. elegans, this is defined by failure of the leaving assay." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003405" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0006001 ;
    owl:annotatedTarget "The apparent partial collapse of the vulval invagination and the elongation of central vulva cells often leading to a flattened appearance." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0008001 ;
    owl:annotatedTarget "Any variation in the processes that govern acquisition of particular cell fates in the embryo, from the time of zygote formation until hatching compared to control." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0008002 ;
    owl:annotatedTarget "Any variation in the processes that govern acquisition of somatic cell fates in the embryo, from the time of zygote formation until hatching compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026662", "WB:WBPerson1843" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0008003 ;
    owl:annotatedTarget "Any variation in a learned olfactory response whereby exposure of animals to odorants during specific developmental times or physiological states results in a lasting memory compared to control. In control animals, this imprinting determines the animal's behavior upon encountering the same odorant at a later time." .

[]
    oboInOwl:hasDbXref "GO:0016049", "WB:rk" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0010001 ;
    owl:annotatedTarget "Variations in the process(es) by which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter compared to control." .

[]
    oboInOwl:hasDbXref "GO:0016043", "WB:rk" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0010002 ;
    owl:annotatedTarget "Variations in the process(es) involved in the assembly and arrangement of cell structures compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712", "WB:rk" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0010003 ;
    owl:annotatedTarget "Animals exhibit a decreased rate programmed cell death pathway leading to the destruction of the cell, viewable in its terminally dismanteled form of a cell corpse, compared to that observed for control cells." .

[]
    oboInOwl:hasDbXref "WB:rk" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0010004 ;
    owl:annotatedTarget "Variations in the process(es) that constitute cell corpse degradation within the engulfing cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000199 ;
    owl:annotatedTarget "Any variation in the progression of the finger-like sensory sensilla that project from the tail and embed in the male fan from its formation to the mature structure when compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000200 ;
    owl:annotatedTarget "Variations in the progression of structures/tissues surrounding a cell over time from its initial formation to its mature form compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000201 ;
    owl:annotatedTarget "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time compared to control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000202 ;
    owl:annotatedTarget "Any variation in the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000018 ;
    owl:annotatedTarget "The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000203 ;
    owl:annotatedTarget "Animals exhibit variations in the characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000204 ;
    owl:annotatedTarget "Variations in the anterior body muscle contraction (aBoc) step of the defecation cycle compared to control animals. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000205 ;
    owl:annotatedTarget "Any variation in the expulsion of gut contents compared to control. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion." .

[]
    oboInOwl:hasDbXref "GO:0045143", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000206 ;
    owl:annotatedTarget "A non-sex chromosome fails to segregate away from its homologous chromosome, resulting in gametes with no or extra copies of the non-sex homolog." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000207 ;
    owl:annotatedTarget "Any variation in the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control ." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002315", "WB:WBPaper00031896", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000208 ;
    owl:annotatedTarget "The mean time between the onset of the defecation motor program is greater than that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002315", "WB:WBPaper00031896", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000209 ;
    owl:annotatedTarget "The mean time between the onset of the defecation motor program is shorter than that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000210 ;
    owl:annotatedTarget "Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000211 ;
    owl:annotatedTarget "The rhythmic contractions of the muscles coordinating the elimination of gut contents are no longer synchronized compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000212 ;
    owl:annotatedTarget "Animals contain body regions that are more narrow or drawn together than adjacent body regions." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000213 ;
    owl:annotatedTarget "Variations in the progression of a zygote from formation (gamete fusion) to just prior to the first cell division compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000214 ;
    owl:annotatedTarget "Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001477", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000215 ;
    owl:annotatedTarget "Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000216 ;
    owl:annotatedTarget "Any variation in the processes that govern acquisition of particular cell fates compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000217 ;
    owl:annotatedTarget "The time in which a muscle contraction event that controls feeding is increased compared to control. Contractions of the pharynx are necessary for bacterial uptake from the surrounding environment." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000218 ;
    owl:annotatedTarget "An excess number of vulval precursor cells receive an inductive signal leading to an increased number of VPCs adopting vulval fates compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000219 ;
    owl:annotatedTarget "Vulval precursor cells receive a decrease in inductive signal leading to fewer VPCs adopting vulval fates compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000220 ;
    owl:annotatedTarget "Any aberrancy in the processes that govern acquisition of vulval cell fates compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0042133", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000221 ;
    owl:annotatedTarget "Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000019 ;
    owl:annotatedTarget "Pharyngeal pumping motion occurs at a slower rate than control animals." .

[]
    oboInOwl:hasDbXref "GO:0042428", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000222 ;
    owl:annotatedTarget "Animals exhibit variations in any chemical reaction or pathway involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0008291", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000223 ;
    owl:annotatedTarget "Animals exhibit variations in any chemical reaction or pathway involving acetylcholine, compared to control. Acetylcholine is the acetic acid ester of the organic base choline." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000020 ;
    owl:annotatedTarget "Pharyngeal pumping motion occurs at intervals that vary from control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000224 ;
    owl:annotatedTarget "Animals do not contain or are unable to maintain a perceivable level of serotonin capable of initiating or maintaining serotonin-dependent cell activity." .

[]
    oboInOwl:hasDbXref "GO:0042427", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000225 ;
    owl:annotatedTarget "Animals are unable to carry out the chemical reactions and pathways resulting in the formation of serotonin." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000906" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000021 ;
    owl:annotatedTarget "Squat animals are dumpy as homozygotes, but roll as heterozygotes." .

[]
    oboInOwl:hasDbXref "GO:0042429", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000226 ;
    owl:annotatedTarget "Animals are unable to carry out any chemical reaction or pathway resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter." .

[]
    oboInOwl:hasDbXref "GO:0034607", "WB:WBPaper00000392", "WB:WBPaper00002109" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000227 ;
    owl:annotatedTarget "The inability of a male to properly turn during mating behavior. In C. elegans, males typically turn via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000565", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000228 ;
    owl:annotatedTarget "Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc31" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000229 ;
    owl:annotatedTarget "Animals are shorter and thinner than control animals at the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002795", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000230 ;
    owl:annotatedTarget "The girth of the region posterior to the vulva is reduced compared to that anterior to the vulva (the Wit phenotype). In C. elegans this phenotype is associated with anteriorward misplacement of the CAN neurons." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000231 ;
    owl:annotatedTarget "Animals exhibit variations in the physical dimensions of its body compared to control animals of the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002795", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000232 ;
    owl:annotatedTarget "Variation in the migration pattern of CAN neurons. In C. elegans, CAN neurons move posteriorly from their birthplace in the head to positions near the middle of the embryo." .

[]
    oboInOwl:hasDbXref "GO:0042417", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000233 ;
    owl:annotatedTarget "Animals exhibit variations in any chemical reaction or pathway involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000234 ;
    owl:annotatedTarget "Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0042416", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000235 ;
    owl:annotatedTarget "Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine." .

[]
    oboInOwl:hasDbXref "GO:0042420", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000236 ;
    owl:annotatedTarget "Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031455", "WB:WBPaper00031570", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000237 ;
    owl:annotatedTarget "Animals extend intensity of roaming and or dwelling activity compared to control animals. In C. elegans, hyperactivity may include an increase in nose-lifts per minute." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031455", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000238 ;
    owl:annotatedTarget "Animals decrease intensity or rate of roaming and or dwelling activity compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005610", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000239 ;
    owl:annotatedTarget "The descendants of a vulval precursor cell exhibit altered developmental programs compared to their counterparts in control animals. In C. elegans, the VPCs are P3.p-P8.p." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000240 ;
    owl:annotatedTarget "The processes governing the expansion of blast cell populations vary, such that cell populations are decreased compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000241 ;
    owl:annotatedTarget "Animals exhibit an increase in the quantity of cells that have undergone programmed cell death but have not been engulfed." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000242 ;
    owl:annotatedTarget "The epidermal cells of the embryo fail to elongate. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000243 ;
    owl:annotatedTarget "Removal of cell corpses through a dedicated engulfment pathway is defective." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000244 ;
    owl:annotatedTarget "Cells fail to complete the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003627", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000245 ;
    owl:annotatedTarget "Variations in the movement of sex myoblasts compared to control animals. In C. elegans, the larval SM migrate anteriorly to the precise center of the developing hermaphrodite gonad." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031896", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000246 ;
    owl:annotatedTarget "Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc31" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000022 ;
    owl:annotatedTarget "Animals are longer than control animals at the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000247 ;
    owl:annotatedTarget "Failure to execute the characteristic response to sodium as defined by control animals. In C. elegans, sodium is typically an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0000247 ;
    owl:annotatedTarget "sodium acetate chemotaxis defective" .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000248 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000249 ;
    owl:annotatedTarget "Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals." .

[]
    oboInOwl:hasDbXref "GO:0046333", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000250 ;
    owl:annotatedTarget "Animals exhibit variations in any chemical reaction or pathway involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000251 ;
    owl:annotatedTarget "Animals do not contain or are unable to maintain a perceivable level of octopamine capable of initiating or maintaining dopamine-dependent cell activity." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000252 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000253 ;
    owl:annotatedTarget "Animals exhibit a lack of consistency, regularity, or uniformity while traveling from one location to another." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000254 ;
    owl:annotatedTarget "Failure to execute the characteristic response to chloride. In C. elegans, chloride is typically an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000255 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000256 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000257 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." .

[]
    oboInOwl:hasDbXref "GO:0032940", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000258 ;
    owl:annotatedTarget "Variations in the regulated release of substances by a cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000822", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000259 ;
    owl:annotatedTarget "Variations in the regulated release of substances by nonneuronal cells that enclose or ensheath the tips of the sensory dendrites compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028924", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000260 ;
    owl:annotatedTarget "The regulated release of materials by sheath cells is disrupted." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028924", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000261 ;
    owl:annotatedTarget "Amphid sheath cells lack the ability to secrete vesicles and their contents within the amphid pocket." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000262 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000263 ;
    owl:annotatedTarget "The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001481", "WB:WBPaper00002033", "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000264 ;
    owl:annotatedTarget "Failure to execute the characteristic response to cAMP as defined by control animals. In C. elegans, cAMP is typically an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:cab", "WB:cgc1786" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000265 ;
    owl:annotatedTarget "Movement towards typically attractive volatile organic chemicals is altered as defined by control animals. In C. elegans, these odorants are typically sensed by the AWA and AWC neurons." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000266 ;
    owl:annotatedTarget "Variations that disrupt stereotypical cleavage patterns (such as cleavage rate, division axes or asymmetric division) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000267 ;
    owl:annotatedTarget "Any variation that causes a delay in the stereotypical cleavage event compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000268 ;
    owl:annotatedTarget "Any variation that causes a delay in the stereotypical cleavage pattern of the P cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000269 ;
    owl:annotatedTarget "OBSOLETE. Animals display a phenotype that has not yet been assigned to a current classification." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000270 ;
    owl:annotatedTarget "Seemingly unrelated variations that concurrently occur during early embryonic development compared to control animals. In C. elegans, this can include multiple pronuclei, aberrant cytoplasmic texture, decrease in overall pace of development and osmotic sensitivity." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000023 ;
    owl:annotatedTarget "Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000272 ;
    owl:annotatedTarget "The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate does not conform to the pattern observed in control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7388" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000273 ;
    owl:annotatedTarget "The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000274 ;
    owl:annotatedTarget "Animals lay eggs that are inviable." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000275 ;
    owl:annotatedTarget "Organisms respond to UV at a lower dose or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000276 ;
    owl:annotatedTarget "Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0048511", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000277 ;
    owl:annotatedTarget "The timing of a biological cycle that recurs with regularity is delayed compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000278 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency or translucency of a particular body region." .

[]
    oboInOwl:hasDbXref "GO:0034609", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000279 ;
    owl:annotatedTarget "Males exhibit defects in the insertion of the male copulatory spicules into the mating partner. In C. elegan spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000280 ;
    owl:annotatedTarget "The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000281 ;
    owl:annotatedTarget "Variations in the progression of the muscles of the adult male reproductive system over time form their initial formation to their mature structure compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000282 ;
    owl:annotatedTarget "Variations in the progression of the muscles of the adult hermaphrodite reproductive system over time form their initial formation to their mature structure compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003386", "WB:WBPaper00006298", "WB:WBPaper00027236", "WB:WBPaper00027316", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000283 ;
    owl:annotatedTarget "Animals exhibit defects in the continuity of lumen between the vulva and uterus compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0007320", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000284 ;
    owl:annotatedTarget "Any defect in the process whereby a male inseminates his partner by introducing sperm into the genital tract." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000285 ;
    owl:annotatedTarget "The extreme ends of any of the finger-like sensory sensilla that project from the tail and embed in the male fan appear bloated or distended." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000286 ;
    owl:annotatedTarget "Embryos fail to be organized in the same manner as observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000288 ;
    owl:annotatedTarget "Variations in the progression of the lineages that gives rise to all germ cells, lying in the region adjacent to the proximal gonad (on the side furthest from the founder cells of the somatic gonad), over time compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000289 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000290 ;
    owl:annotatedTarget "Animals lack fully specialized male gametes that are competent for fertilization." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000291 ;
    owl:annotatedTarget "Hermaphrodites lack fully specialized female gametes that are competent for fertilization." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000005 ;
    owl:annotatedTarget "Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000292 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a organ system." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000024 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000293 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the alimentary system." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000294 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that decrease the transparency/translucency of the intestine." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005836", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000295 ;
    owl:annotatedTarget "Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000296 ;
    owl:annotatedTarget "The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) are deformed. In C. elegans males there are two copulatory spicules." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000297 ;
    owl:annotatedTarget "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000298 ;
    owl:annotatedTarget "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are shifted from their customary place." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000214", "WB:WBPaper00000938", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000299 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000214", "WB:WBPaper00000503", "WB:WBPaper00000822", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000300 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in control animals. Sheath cells in C.elegans have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029151", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000301 ;
    owl:annotatedTarget "A migrating distal tip cell (DTC) fails to follow the stereotypical path. In C. elegans this path is U-shaped and results in the formation of reflexed gonadal arm." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001786" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000302 ;
    owl:annotatedTarget "Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001786" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000303 ;
    owl:annotatedTarget "Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc1786" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000304 ;
    owl:annotatedTarget "Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive." .

[]
    oboInOwl:hasDbXref "GO:0043695", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000305 ;
    owl:annotatedTarget "Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that influences behavior in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000306 ;
    owl:annotatedTarget "Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000307 ;
    owl:annotatedTarget "Animals fail to detect a pheromone stimulus that induces dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000308 ;
    owl:annotatedTarget "Any variation in the processes that govern development of the dauer larva, a developmentally arrested, larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions. In C. elegans this is an alternative third larval stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000309 ;
    owl:annotatedTarget "Any variation that decreases the ability of dauer larva to tolerate the exposure to sodium dodecyl sulfate (a detergent) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00005654", "WB:WBPaper00006395", "WB:WBPaper00024497", "WB:cab", "WB:cgc31" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000025 ;
    owl:annotatedTarget "Fluid-filled blisters appear on the cuticle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000310 ;
    owl:annotatedTarget "Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals." .

[]
    oboInOwl:hasDbXref "GO:0042446", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000312 ;
    owl:annotatedTarget "Animals are incapable of synthesizing pheromones that induce dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026997", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000313 ;
    owl:annotatedTarget "Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000314 ;
    owl:annotatedTarget "Animals are slight or meager in body size compared to control animals at the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000315 ;
    owl:annotatedTarget "Any variation with respect to perception or response to mechanical stimuli compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000502", "WB:WBPaper00001133", "WB:WBPaper00001705", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000316 ;
    owl:annotatedTarget "Failure to execute a characteristic response when struck or stroked in the posterior region. In C. elegans, animals move forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000317 ;
    owl:annotatedTarget "Animals are deficient in the foraging response in which an animal quickly pulls its head away from a stimulus to the nose (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0006629", "WB:WBPaper00005707", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000026 ;
    owl:annotatedTarget "Animals are unable to take up or store lipids. In C. elegans, this defect results in pale, skinny and arrested larva." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000318 ;
    owl:annotatedTarget "Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells." .

[]
    oboInOwl:hasDbXref "GO:0008152", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000027 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000319 ;
    owl:annotatedTarget "Animals have increased girth and increased length compared to control animals at the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000320 ;
    owl:annotatedTarget "Animals show a decrease in survivorship after thawing compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000321 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000322 ;
    owl:annotatedTarget "The extreme anterior part of the body appears blunted in shape." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000323 ;
    owl:annotatedTarget "The most anterior portion of the animal appears bloated or distended." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000324 ;
    owl:annotatedTarget "Animals exhibit a decreased body length compared to control animals of the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000325 ;
    owl:annotatedTarget "Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000326 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000327 ;
    owl:annotatedTarget "Any defect in the muscle contractions of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001696" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000328 ;
    owl:annotatedTarget "Variations in the rhythmic contractions of the posterior pharynx (terminal bulb), such as timing, strength etc. In C. elegans contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001696" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000329 ;
    owl:annotatedTarget "The rhythmic contractions of pharyngeal compartments are no longer synchronized compared to control. In C. elegans the corpus and terminal bulb normally contract simultaneously." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000330 ;
    owl:annotatedTarget "Defects in rhythmic pharyngeal relaxations compared to control animals. In C. elegans pharyngeal relaxation follows a contraction event and facilitates bacterial trapping within the pharynx while expelling liquid." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000331 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000332 ;
    owl:annotatedTarget "Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000333 ;
    owl:annotatedTarget "The time interval of the stereotyped sequence of muscle contractions by individual pharyngeal muscles that act to draw food into the pharynx is shorter compared to that observed in control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001696" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000334 ;
    owl:annotatedTarget "Failure of muscle contractions in the corpus and isthmus to trap and transport bacteria posteriorly in the pharynx." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001696" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000335 ;
    owl:annotatedTarget "Failure of pharyngeal contractions to trap and transport bacteria posteriorly. In C. elegans this defect results in a distention of the pharyngeal lumen." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001696" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000336 ;
    owl:annotatedTarget "Variations in the rhythmic relaxations of the posterior pharynx (terminal bulb). In C. elegans the relaxation of the terminal bulb returns the grinder to its relaxed forward position." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000337 ;
    owl:annotatedTarget "Failure of the grinder to come to a full relaxed position between pumps compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026735", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000338 ;
    owl:annotatedTarget "Swelling in the post anal region compared to control. In C. elegans this swelling can be associated with infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000339 ;
    owl:annotatedTarget "Worms sporatically appear turgid or swollen as a result of an excess number of eggs being retained in the uterus." .

[]
    oboInOwl:hasDbXref "GO:0006396", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000028 ;
    owl:annotatedTarget "Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000340 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029209", "WB:WBPaper00030758", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000029 ;
    owl:annotatedTarget "Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000341 ;
    owl:annotatedTarget "Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000342 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the adult male tail including the lateral fan and rays compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000344 ;
    owl:annotatedTarget "Any of the contents that comprise the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus extend into the external environment through the cloacal opening." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000345 ;
    owl:annotatedTarget "Any variation that alters the physical partitioning and separation of a vulval precursor cell into daughter cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000346 ;
    owl:annotatedTarget "Adult animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000347 ;
    owl:annotatedTarget "Any variation in the progression of the cuticle-lined sinus opening on the posterior ventral surface of the animal over time from its formation to its mature structure compared to control (Wormatlas). The function of the rectum is to excrete waste products from the alimentary system." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000349 ;
    owl:annotatedTarget "A semi-paralysed body phenotype in which muscle tone is lost and the animal fails to actively control its body shape (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000350 ;
    owl:annotatedTarget "Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the hermaphrodite tail compared to control." .

[]
    oboInOwl:hasDbXref "GO:0035188", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000351 ;
    owl:annotatedTarget "Animals fail to emerge from an egg shell." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000352 ;
    owl:annotatedTarget "Backward movement is not coordinated as in control. This often causes jerky or spastic backward locomotion." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000353 ;
    owl:annotatedTarget "Animals spend more time backing compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000354 ;
    owl:annotatedTarget "Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000355 ;
    owl:annotatedTarget "Specialization of HSN precursor cells to mature HSN neurons occurs at an earlier stage of development compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005566", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000356 ;
    owl:annotatedTarget "The progression of immature germ cells to functional sperm is retarded compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001075", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000357 ;
    owl:annotatedTarget "Animals lay inactivated oocytes. In C elegans this may be due to perturbations that eliminate spermatogenesis or result in the production of defective sperm." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000358 ;
    owl:annotatedTarget "Animals execute supernumerary cell divisions post-hatching." .

[]
    oboInOwl:hasDbXref "GO:0040007", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000030 ;
    owl:annotatedTarget "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00030877", "WB:WBperson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000359 ;
    owl:annotatedTarget "Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response." .

[]
    oboInOwl:hasDbXref "GO:0099636", "WB:WBPaper00050908", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000360 ;
    owl:annotatedTarget "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is impaired." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000361 ;
    owl:annotatedTarget "Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000362 ;
    owl:annotatedTarget "Any variation in the progression of the fluid-filled compartment inside the developing embryo at the onset of gastrulation over time from its formation to its mature structure compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000363 ;
    owl:annotatedTarget "Any variation that delays the physical partitioning and separation of a cell into daughter cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025094" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000364 ;
    owl:annotatedTarget "The birefringent inclusions typically found in the intestinal cytoplasm accumulate extracellularly in the intestinal lumen." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000365 ;
    owl:annotatedTarget "Variations in the ability of an embryo to maintain osmotic balance. In C.elegans this can result in an embryo filling the egg shell and lysing." .

[]
    oboInOwl:hasDbXref "WB:WBPerson101" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000366 ;
    owl:annotatedTarget "Cessation of development that normally occurs in C. elegans 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000367 ;
    owl:annotatedTarget "Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson101" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000368 ;
    owl:annotatedTarget "Cessation of development that normally occurs in C. elegans 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000369 ;
    owl:annotatedTarget "Cessation of development during the final two stages in embryogenesis, 'early pretzel' stage and 'late pretzel' stage, just prior to hatching. The animal now is folded into four lengths within the eggshell and resembles a pretzel. By early pretzel stage, the head begins to move independently from the body (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000370 ;
    owl:annotatedTarget "The fertilized oocytes have a greater than standard length measured end to end compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000371 ;
    owl:annotatedTarget "The physical partitioning and separation of a cell into daughter cells is interupted." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000372 ;
    owl:annotatedTarget "Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000373 ;
    owl:annotatedTarget "The overall structure or appearance of fertilized oocytes that are laid exhibit nonconsistent and significant deviation from that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000374 ;
    owl:annotatedTarget "The time interval in which early embryonic cell divisions occur is increased compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000375 ;
    owl:annotatedTarget "The time interval in which late embryonic cell divisions occur is increased compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000376 ;
    owl:annotatedTarget "Animals lack the inner space of the uterus through which the fertilized egg passes on its way out of the nematode via the vulva (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000377 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of the internal space of the excretory canal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000378 ;
    owl:annotatedTarget "Pharyngeal muscle contractions show less displacement than that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000031" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000379 ;
    owl:annotatedTarget "The most anterior portion of the animal contains a V-shaped indentation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002315", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000380 ;
    owl:annotatedTarget "The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step in C. elegans specialized enteric muscles contract to expel the contents of the gut through the anus." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000381 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000382 ;
    owl:annotatedTarget "Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000383 ;
    owl:annotatedTarget "The de novo synthesis of any lipid species is reduced compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00004403", "WB:WBPaper00004651", "WB:WBPaper00004769", "WB:WBPaper00005654", "WB:WBPaper00006395", "WB:WBPaper00024497", "WB:WBPerson557", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000031 ;
    owl:annotatedTarget "Any variation that causes a reduction in growth rate compared to control." .

[]
    oboInOwl:hasDbXref "GO:0048846", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000384 ;
    owl:annotatedTarget "Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPaper00000565", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000032 ;
    owl:annotatedTarget "Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000385 ;
    owl:annotatedTarget "Animals produce an increased sperm population compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032006", "WB:WBPaper00032243", "WB:WBPaper00032356", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000386 ;
    owl:annotatedTarget "Programmed cell death of germ cells caused by exposure to DNA-damaging chemical agents does not occur to the same extent as it does in control animals." .

[]
    oboInOwl:hasDbXref "GO:0030317", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000387 ;
    owl:annotatedTarget "The mature male gametes lack self-propelled movement." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000388 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the mature male gamete, which merges with an oocyte to create a fertilized embryo copared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001075", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000389 ;
    owl:annotatedTarget "Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000884", "WB:WBPaper00027300", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000390 ;
    owl:annotatedTarget "Spermatids fail to mature into active sperm. In C. elegans round sessile spermatids mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000391 ;
    owl:annotatedTarget "Animals lack one or more of the stereotyped muscle contractions that result in defecation compared to control. In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000392 ;
    owl:annotatedTarget "Animals exhibit an increase in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000393 ;
    owl:annotatedTarget "Characteristic movement of cells from one site to another is abolished compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000394 ;
    owl:annotatedTarget "Any variation in the movement of a protein through a gel matrix when an electric field is applied compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000395 ;
    owl:annotatedTarget "Animals are agametic (lack mature germ cells)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005086", "WB:WBPaper00029151", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000396 ;
    owl:annotatedTarget "Gonadal arms do not bend or curve. In C. elegans gonad arms normally reflex to form a stereotypical U-shaped pattern." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000502" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000397 ;
    owl:annotatedTarget "Animals do not respond to prodding with a fine platinum wire or similar tool compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000502" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000398 ;
    owl:annotatedTarget "Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000399 ;
    owl:annotatedTarget "Any variation in the progression of the components of the gonad that are separate from the germline proper over time from its formation to its mature structure compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000400 ;
    owl:annotatedTarget "The developmental progression of the set of precursor cells that later give rise to the somatic tissues of the gonadal tract is impaired (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000401 ;
    owl:annotatedTarget "Animals lack the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029071", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000402 ;
    owl:annotatedTarget "Lawn avoidance refers to behavior in which animals initially enter the bacterial lawn but later exit and remain near the edge of the bacteria. Lawn avoidance is often a response to bacterial food, that is pathogenic or low quality to the animal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028400" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000403 ;
    owl:annotatedTarget "Any defect in the movement of sperm out of the seminal vesicle and into the vas deferens following tonic insertion of spicules into the mating partner compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:6494891" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000033 ;
    owl:annotatedTarget "The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues." .

[]
    oboInOwl:hasDbXref "GO:0035188", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000404 ;
    owl:annotatedTarget "The emergence of larvae from their protective egg shells is retarded compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000405 ;
    owl:annotatedTarget "The size of haploid female germ cells (oocytes) are significantly larger compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000406 ;
    owl:annotatedTarget "Animals have protrusions or bumps on their exterior which are not characteristic of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000408 ;
    owl:annotatedTarget "The process through which a dauer larva reverts to normal developmental programs is blocked." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000409 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any of its parts at different stages of the lifecycle, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000410 ;
    owl:annotatedTarget "Animals lack the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001366", "WB:WBPaper00002764", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000411 ;
    owl:annotatedTarget "Animals die as rigid, rod-like larva. In C. elegans this defect is often caused by the misspecification of the excretory duct cell." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002314" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000412 ;
    owl:annotatedTarget "Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000413 ;
    owl:annotatedTarget "Pharyngeal muscle is immobilized resulting in lack of pumping or lack of response to external stimulation." .

[]
    oboInOwl:hasDbXref "GO:0045165", "WB:WBPaper00002924", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000414 ;
    owl:annotatedTarget "The cell takes on a different identity from which it was initially committed." .

[]
    oboInOwl:hasDbXref "GO:0070265", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000415 ;
    owl:annotatedTarget "Animals exhibit variations in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000416 ;
    owl:annotatedTarget "Variations in the generation of the nutrient protein produced by intestinal cells and secreted by them into the pseudocoelom, from which it can be shared with other tissues in the body compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000417 ;
    owl:annotatedTarget "The process of physical partitioning and separation of a cell into daughter cells is abolished." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000418 ;
    owl:annotatedTarget "The physical partitioning and separation of an intestinal cell into daughter cells is abolished." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000419 ;
    owl:annotatedTarget "Animals die at the L3 stage of the life cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005079", "WB:WBPerson2021", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000034 ;
    owl:annotatedTarget "Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000420 ;
    owl:annotatedTarget "Animals respond to levamisole at a lower concentration or a shorter exposure compared to control animals. Levamisole is a cholinergic agonist." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000484", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000421 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of levamisole that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000484" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000422 ;
    owl:annotatedTarget "Animals exhibit spasmodic muscle twitching superimposed on normal sinusoidal motion." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000423 ;
    owl:annotatedTarget "Any variation in the contractions of the muscles in the most anterior body region of the animal compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000424 ;
    owl:annotatedTarget "Any variation in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000425 ;
    owl:annotatedTarget "Any variation that results in a decrease in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000426 ;
    owl:annotatedTarget "Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000427 ;
    owl:annotatedTarget "Animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000428 ;
    owl:annotatedTarget "Adult animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000429 ;
    owl:annotatedTarget "Any variation in the progression of the specialized structures of the animal which allow the successful transfer of sperm from one organism to another, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000430 ;
    owl:annotatedTarget "Any variation in the progression of the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm over time from its formation to its mature structure compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000431 ;
    owl:annotatedTarget "Any variation in the progression of the specialized structures of a hermaphrodite which allow the successful transfer of sperm from a male, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000432 ;
    owl:annotatedTarget "Animals lack the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0006260", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000433 ;
    owl:annotatedTarget "Variations in the processes involving the production of new DNA strands compared to control." .

[]
    oboInOwl:hasDbXref "GO:0003006", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000434 ;
    owl:annotatedTarget "The developmental process by which a progressive change in the state of some part of an organism specifically contributing to its ability to form offspring is impaired." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000436 ;
    owl:annotatedTarget "Any variation in the placement of a protein within in a cell or cellular compartment compared to control." .

[]
    oboInOwl:hasDbXref "GO:0040034", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000438 ;
    owl:annotatedTarget "Variations that result in the deceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0040034", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000439 ;
    owl:annotatedTarget "Variations that result in the acceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00004651", "WB:WBPaper00005654", "WB:WBPaper00006395", "WB:WBPaper00024497", "WB:WBPaper00025054", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000006 ;
    owl:annotatedTarget "Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000440 ;
    owl:annotatedTarget "The structure made by the processes of the excretory canal cell is increased in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000441 ;
    owl:annotatedTarget "Tails change shape and undergo retraction thereby forming a 'peloderan' or 'rounded' adult tail." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000442 ;
    owl:annotatedTarget "The developmental progression of a larva over time, from its formation to its mature structure is delayed compared to control. The larva is the early, immature form of an animal between hatching and adulthood." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000443 ;
    owl:annotatedTarget "Any variation in the appearance of the elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000444 ;
    owl:annotatedTarget "The length of the adult male tail, including the lateral fan and rays, is extended compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000445 ;
    owl:annotatedTarget "Males generate yolk, the nutrient protein, normally produced and secreted by hermaphrodite or female intestinal cells." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000446 ;
    owl:annotatedTarget "Animals execute extra larval molts compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000447 ;
    owl:annotatedTarget "Variations in the progression of an animal over time from the end of larval stage to a mature adult compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000035 ;
    owl:annotatedTarget "Any variation in the overall structure or appearance of the animal as it progresses from hatching to adult compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000448 ;
    owl:annotatedTarget "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time in adults compared to control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001439" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000449 ;
    owl:annotatedTarget "A duplication of the developmental program that forms the adult-type rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000451 ;
    owl:annotatedTarget "Any irregular swelling in discrete regions of the head." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000452 ;
    owl:annotatedTarget "Any irregular swelling in discrete regions of the tail, usually caused by a local defect in the normal smooth tapering of the hypodermis and/or cuticle (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000453 ;
    owl:annotatedTarget "Any irregular swelling in discrete regions of the body region between the head and the tail." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000036 ;
    owl:annotatedTarget "Any variation in the overall structure or appearance of the animal after it has completed progression through the larval stages compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000454 ;
    owl:annotatedTarget "The anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring)of the body appears distorted, usually due to uncharacteristic winding." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000455 ;
    owl:annotatedTarget "Animals exhibit abrupt transitions while traveling from one location to another." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000456 ;
    owl:annotatedTarget "Variations in characteristic response with respect to perception or transmission of a touch stimulus compared to responses in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000457 ;
    owl:annotatedTarget "Animals show enhanced suceptibility to deprivation of nourishment, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000458 ;
    owl:annotatedTarget "Animals show enhanced tolerance to deprivation of nourishment, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001075", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000037 ;
    owl:annotatedTarget "Any variation in the overall structure or appearance of fertilized oocytes that are laid compared to those laid by control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000459 ;
    owl:annotatedTarget "Animals exhibit variations in their response to any chemical substance that is used for killing pests, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027633", "WB:WBPaper00031094", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000038 ;
    owl:annotatedTarget "The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000460 ;
    owl:annotatedTarget "Animals exhibit variations in their response to paraquat compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000461 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000462 ;
    owl:annotatedTarget "Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031296" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasBroadSynonym ;
    owl:annotatedSource obo:WBPhenotype_0000462 ;
    owl:annotatedTarget "reactive oxygen species hypersensitive" .

[]
    oboInOwl:hasDbXref "GO:0008152", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000463 ;
    owl:annotatedTarget "Animals exhibit variations in processes that are responsible for chemical changes compared to control animals. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000464 ;
    owl:annotatedTarget "Animals exhibit variations in their response to oxygen compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000465 ;
    owl:annotatedTarget "Animals fail to respond to the high concentrations of oxygen that elicit a response in control animals." .

[]
    oboInOwl:hasDbXref "GO:0055093", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000466 ;
    owl:annotatedTarget "Animals respond to hyperoxic (high oxygen tension) conditions after a shorter exposure time compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033040", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000467 ;
    owl:annotatedTarget "Animals exhibit an increase in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000468 ;
    owl:annotatedTarget "Animals exhibit a decrease in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001954", "WB:WBPaper00031356", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000469 ;
    owl:annotatedTarget "The daughters of the Q neuroblasts exhibit variation in their characteristic movements compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001836", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000470 ;
    owl:annotatedTarget "Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001304", "WB:WBPaper00003058", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000471 ;
    owl:annotatedTarget "Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000472 ;
    owl:annotatedTarget "Animals lack the early blast cells that give rise to the gut tissue (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000007 ;
    owl:annotatedTarget "A worm carcass is formed with retained eggs that hatch inside." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000473 ;
    owl:annotatedTarget "Animals become increasingly sluggish/immobilized as they age." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000474 ;
    owl:annotatedTarget "Any variation in the connection of the cell(s) whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000475 ;
    owl:annotatedTarget "Animals fail to establish or maintain the connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000476 ;
    owl:annotatedTarget "The connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues diminishes over time." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000477 ;
    owl:annotatedTarget "Any variation in the change in direction of a wave of light after passage through the nucleolus compared to control. The nucleolus is a small dense body in the nucleus." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002214" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000478 ;
    owl:annotatedTarget "Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000479 ;
    owl:annotatedTarget "Eggs show deficiencies in chroma resulting in increased translucency." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001786" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000480 ;
    owl:annotatedTarget "Failure to execute the characteristic response to pyrazine as defined by control animals. In C. elegans pyrazine is typically an attractant." .

[]
    oboInOwl:hasDbXref "GO:0008340", "WB:WBPaper00005863", "WB:WBPaper00026717", "WB:WBPerson557", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000039 ;
    owl:annotatedTarget "Adult life span is either longer or shorter than typical of control animals." .

[]
    oboInOwl:hasDbXref "GO:0050919", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000481 ;
    owl:annotatedTarget "Any variation in the directed movement of an animal in response to chemical repellants as defined by control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001374" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000482 ;
    owl:annotatedTarget "Failure to execute the characteristic response to garlic as defined by control animals. In C. elegans, garlic is typically a repellent." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000483 ;
    owl:annotatedTarget "Animals lack the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000040 ;
    owl:annotatedTarget "Embryos fail to divide and arrest as one-cell embryos." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000484 ;
    owl:annotatedTarget "The organism's size during the embryonic developmental stage is decreased compared to that observed in control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000485 ;
    owl:annotatedTarget "The survival of animals in the alternative larval stage which they enter when placed under conditions of environmental stress is reduced." .

[]
    oboInOwl:hasDbXref "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0000040 ;
    owl:annotatedTarget "catastrophic one cell arrest" .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000486 ;
    owl:annotatedTarget "Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000487 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000488 ;
    owl:annotatedTarget "Animals respond to chloroquine at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000489 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000490 ;
    owl:annotatedTarget "The components of the feeding organ fail to be arranged in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000491 ;
    owl:annotatedTarget "Any observed morphological defects of the isthmus." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000492 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000493 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the first pharyngeal bulb compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson101" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000494 ;
    owl:annotatedTarget "Cessation of development that normally occurs in C. elegans 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000495 ;
    owl:annotatedTarget "Animals have finger-like sensory sensilla (rays) that are present in places they are normally not found, when compared to the location in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000496 ;
    owl:annotatedTarget "Males lack the specialized sensory papillae that lie along the posterior half of the body." .

[]
    oboInOwl:hasDbXref "GO:0030104", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000041 ;
    owl:annotatedTarget "Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000497 ;
    owl:annotatedTarget "Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000498 ;
    owl:annotatedTarget "Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000499 ;
    owl:annotatedTarget "Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000500 ;
    owl:annotatedTarget "Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000501 ;
    owl:annotatedTarget "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the left-handed direction. In liquid media, wave propogation is helical rather than planar." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000502 ;
    owl:annotatedTarget "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the right-handed direction. In liquid media, wave propogation is helical rather than planar." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000503 ;
    owl:annotatedTarget "Any variation in the multiple rounds of DNA replication that take place without chromosome condensation, segregation or cytokinesis compared to control. In C. elegans this process is normally seen in intestinal nuclei during each larval lethargus which results in adult intestinal nuclei with 32 copies (32C) of each chromosome(Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000504 ;
    owl:annotatedTarget "Any variation in the process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPaper00001328", "WB:WBPaper00002149", "WB:WBPaper00029016", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000505 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of any of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control animals. In C. elegans, nine bilateral rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000506 ;
    owl:annotatedTarget "The adult male tail, including the lateral fan and rays, appears bloated or distended." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000507 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of acetylcholine compared to control animals at a defined stage. Acetylcholine is the acetic acid ester of the organic base choline." .

[]
    oboInOwl:hasDbXref "GO:0070478", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000508 ;
    owl:annotatedTarget "Animals exhibit a decrease in the regulated breakdown of mRNA transcripts in which an amino-acid codon has changed to a premature stop codon and the 3 prime end is not protected by a poly(A) tail." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001075", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000509 ;
    owl:annotatedTarget "Variation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001738", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000510 ;
    owl:annotatedTarget "The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000042 ;
    owl:annotatedTarget "The progression through stages between fertilization to hatching are temporally retarded." .

[]
    oboInOwl:hasDbXref "GO:0007097", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000511 ;
    owl:annotatedTarget "Variations in the directed movement of the nucleus to a specific location within a cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031891", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000512 ;
    owl:annotatedTarget "Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006135", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000514 ;
    owl:annotatedTarget "When prodded on the head, worm contracts and then relaxes along its entire body without moving backwards, compared to a control worm which contracts its anterior end and backs away in response to prodding." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000515 ;
    owl:annotatedTarget "Variations in any process whose specific outcome is the development and/or maintenance of the ventral nerve cord." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000516 ;
    owl:annotatedTarget "The longitudinal nerve cord of the midbody region, connecting the nerve ring and tail ganglia, is not arranged in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "GO:0007610", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000517 ;
    owl:annotatedTarget "Variations in the specific actions or reactions in response to external or internal stimuli compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0032502", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000518 ;
    owl:annotatedTarget "Variations in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000519 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000520 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any of its parts compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000521 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000522 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of a certain defined body area of an animal in response to external or internal stimuli compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000523 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a specific chemical compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000043 ;
    owl:annotatedTarget "Variations in the progression time of an animal from pronuclei meeting to adulthood compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000524 ;
    owl:annotatedTarget "Animals exhibit variations in their response to bleach compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0007610", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000525 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in control organisms." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000526 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a cell." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000044 ;
    owl:annotatedTarget "Egg is smaller or larger compared to eggs of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000527 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025054", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000045 ;
    owl:annotatedTarget "The developmental progression of an animal after the embryonic stage, over time, from its formation to its mature structure is delayed compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000528 ;
    owl:annotatedTarget "Variations in the progression of the overall structure or appearance of a discrete region of an animal's anatomy over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000046 ;
    owl:annotatedTarget "More than five minutes between AB and P1 divisions." .

[]
    oboInOwl:hasDbXref "GO:0048468", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000529 ;
    owl:annotatedTarget "Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0048731", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000530 ;
    owl:annotatedTarget "Any variation in the progression of an organismal system from its formation to the mature structure when compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000531 ;
    owl:annotatedTarget "Any variation in the progression of a worm at any time from its fertilization to adulthood compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000532 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of a discrete region of their anatomy compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0005623", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000533 ;
    owl:annotatedTarget "Any variation in the form or composition of the basic structural and functional unit of all organisms compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000534 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00004403", "WB:WBPaper00004651", "WB:WBPaper00005654", "WB:WBPaper00006395", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000535 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0009987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000536 ;
    owl:annotatedTarget "Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000539 ;
    owl:annotatedTarget "Variations in the progression of the anatomical structures that consist of processes of ventral cord motor neurons that send commissures to the dorsal side, as well as processes of certain head and tail neurons, over time from initial formation to mature structure compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027251", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000047 ;
    owl:annotatedTarget "Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000540 ;
    owl:annotatedTarget "Variations in the progression of the process extension from the muscle belly by which the muscle cells reach to the nerve cords to obtain innervation over time from initial formation to mature structure compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001499", "WB:WBPaper00028984", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000541 ;
    owl:annotatedTarget "Axon tracts fail to complete the connection between nerve cords. In C. elegans, these tracts grow circumferentially around the animal, completing the connection between the ventral and dorsal nerve cords." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000542 ;
    owl:annotatedTarget "Animals exhibit an increased girth compared to a control animal of the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000543 ;
    owl:annotatedTarget "Forward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves forward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000544 ;
    owl:annotatedTarget "Backward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves backward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000545 ;
    owl:annotatedTarget "Eggs are retained in the uterus at a later stage when compared with control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000546 ;
    owl:annotatedTarget "Eggs are laid at an earlier stage of development when compared with control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000547 ;
    owl:annotatedTarget "Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000548 ;
    owl:annotatedTarget "Progressive degeneration of muscle." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000549 ;
    owl:annotatedTarget "Progressive degeneration of the head muscle." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000550 ;
    owl:annotatedTarget "Progressive degeneration of muscle along the body wall." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000075", "WB:WBPaper00006375", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000551 ;
    owl:annotatedTarget "Animals exhibit variations in the rate of sharp head to tail turns compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000552 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of GABA compared to control animals at a defined stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000553 ;
    owl:annotatedTarget "Animals exhibit a weak and abnormal birefringency pattern in muscle fibers when examined using polarized optics." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000484", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000554 ;
    owl:annotatedTarget "Any variation in the ability to adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000555 ;
    owl:annotatedTarget "Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000556 ;
    owl:annotatedTarget "Animals show variations in their decreased responsiveness after prolonged or repeated exposure to dopamine compared to that in control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000557 ;
    owl:annotatedTarget "Animals do not exhibit decreased responsiveness after prolonged or repeated exposure to dopamine." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000558 ;
    owl:annotatedTarget "Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000559 ;
    owl:annotatedTarget "Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000560 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000484" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000561 ;
    owl:annotatedTarget "The heads of animals fail to respond to the concentration of levamisole that elicits a response in control animals. In C. elegans, heads contract at >10uM for intact animals and >1uM for cut animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000484" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000562 ;
    owl:annotatedTarget "The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000563 ;
    owl:annotatedTarget "The whole body undergoes longitudinal shortening in response to head touch or tail touch (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002305", "WB:WBPaper00003765", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000564 ;
    owl:annotatedTarget "Muscle contractions that make up the defecation motor program are repeated before the onset of the next cycle unlike in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson363" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000565 ;
    owl:annotatedTarget "The body of an animal assumes a coil-like shape when it attempts to move." .

[]
    oboInOwl:hasDbXref "WB:WBPerson363" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000566 ;
    owl:annotatedTarget "A coiling body that bends ventrally." .

[]
    oboInOwl:hasDbXref "WB:WBperson363" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000567 ;
    owl:annotatedTarget "A coiling body that bends dorsally." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001499", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000568 ;
    owl:annotatedTarget "Animals display variations in the structure or organization of the components of the axon, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001499", "WB:WBPaper00024595", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000569 ;
    owl:annotatedTarget "Animals display markedly swollen areas along their axons, which are larger than synaptic varicosities in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001499", "WB:WBPaper00024595", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000570 ;
    owl:annotatedTarget "Axons of animals contain flattened membrane-bound compartments. In C. elegans, these cisternae-like structures are typically absent." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001499", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000571 ;
    owl:annotatedTarget "Axons of animals exhibit variations in the gross structure or organization of its spherical, membrane-bound, fluid-filled organelles, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000572 ;
    owl:annotatedTarget "Any variation in the processes that govern the extension of neuronal projections." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000573 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "GO:0035188", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000048 ;
    owl:annotatedTarget "Variations in the ability of an animal to emerge from the protective egg shell compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000574 ;
    owl:annotatedTarget "The structure made by the processes of the excretory canal cell is reduced in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0003008" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000575 ;
    owl:annotatedTarget "Animals exhibit variations in a physical or chemical process required for organs or tissues to carry out their normal functions or for their ability to perceive and respond to stimuli compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000576 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli." .

[]
    oboInOwl:hasDbXref "GO:0048871", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000577 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000578 ;
    owl:annotatedTarget "Variations in the progression of a discrete axis of an animal's anatomy over time, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000579 ;
    owl:annotatedTarget "Variations in the progression of the overall structure or appearance of any anterior/posterior section of an animal's anatomy over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000580 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of a certain body region of an animal in response to external or internal stimuli compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000581 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of a discrete axis (dorsal/ventral/anterior/posterior/transverse) of their anatomy, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000582 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any anterior/posterior section of their anatomy compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00004403", "WB:WBPaper00004651", "WB:WBPaper00005654", "WB:WBPaper00006395", "WB:WBPaper00024497", "WB:cab", "WB:cgc31" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000583 ;
    owl:annotatedTarget "Worms are shorter and stouter than control animals at the same developmental stage." .

[]
    oboInOwl:hasDbXref "GO:0007268", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000584 ;
    owl:annotatedTarget "Any variation in the process of communication across a synapse between a neuron and a target cell (neuron, muscle, or secretory cell) compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0019725", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000585 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000586 ;
    owl:annotatedTarget "Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000587 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000588 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000589 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000590 ;
    owl:annotatedTarget "Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000049 ;
    owl:annotatedTarget "Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000591 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a specific metal compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000592 ;
    owl:annotatedTarget "Animals exhibit variations in their response to copper compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000593 ;
    owl:annotatedTarget "Animals respond to copper at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0016477", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000594 ;
    owl:annotatedTarget "Any variation in the orderly movement of a cell from one site to another." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000595 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of the head in response to external or internal stimuli compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000596 ;
    owl:annotatedTarget "Activity characteristic of the body is altered compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000597 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of the tail in response to external or internal stimuli compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000598 ;
    owl:annotatedTarget "Variations in the form, structure or composition of the series of related tissues lying within the body cavity and devoted to feeding and digestion compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000599 ;
    owl:annotatedTarget "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the coelomic system, compared to control. The coelom is the fluid compartment that is in contact with internal organ." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000600 ;
    owl:annotatedTarget "Variations in the form, composition or structure of the epithelial system that serves to protect the organism from the external environment compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000601 ;
    owl:annotatedTarget "Variations in the form, structure or composition of related tissues that allow the animal to secrete saline fluid and maintain a proper salt balance compared to control. In C. elegans, four cell types (1 pore cell, 1 duct cell, 1 canal cell and a fused pair of gland cells) make up the excretory system (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0007517", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000603 ;
    owl:annotatedTarget "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPaper00004403", "WB:WBPaper00004540", "WB:WBPaper00004651", "WB:WBPaper00004769", "WB:WBPaper00005654", "WB:WBPaper00024497", "WB:WBPaper00024925", "WB:WBPaper00025054", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000050 ;
    owl:annotatedTarget "Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000604 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals." .

[]
    oboInOwl:hasDbXref "GO:0009790", "WB:WBPaper00004811", "WB:WBPaper00024944", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000051 ;
    owl:annotatedTarget "The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000605 ;
    owl:annotatedTarget "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001109", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000052 ;
    owl:annotatedTarget "Lethality caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis." .

[]
    oboInOwl:hasDbXref "GO:0003008", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000606 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the alimentary system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc1894" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000053 ;
    owl:annotatedTarget "Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae." .

[]
    oboInOwl:hasDbXref "GO:0003008", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000607 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the coelomic system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0003008", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000608 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the epithelial system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0003008", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000609 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the excretory/secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0003008", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000610 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0003008", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000611 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0003008", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000612 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0003008", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000613 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the reproductive system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0002119", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000054 ;
    owl:annotatedTarget "The animal dies at any time between hatching and onset to adulthood." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000614 ;
    owl:annotatedTarget "Any variation in the progression of the GLR accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000214", "WB:WBPaper00000932", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000615 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside." .

[]
    oboInOwl:hasDbXref "GO:0045202", "WB:WBPaper00027305", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000616 ;
    owl:annotatedTarget "Animals display variations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly opposite the post-synaptic target and separated by a synaptic cleft." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000617 ;
    owl:annotatedTarget "Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000618 ;
    owl:annotatedTarget "Any variation in the progression of the coelomic system over time, from its formation to its mature state compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000619 ;
    owl:annotatedTarget "Any variation in the progression of the epithelial system over time, from its formation to its mature state compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000620 ;
    owl:annotatedTarget "Any variation in the progression of the excretory secretory system over time, from its formation to its mature state compared to control. The excretory secretory system consists of the excretory system and its associated glands." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000621 ;
    owl:annotatedTarget "Variations in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste. In C. elegans, the excretory system is comprised of the excretory cell, excretory duct cell and excretory socket cell." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000622 ;
    owl:annotatedTarget "Any variation in the progression of the muscle system over time, from its formation to its mature state compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000055 ;
    owl:annotatedTarget "Larvae arrest during early larval development. In C. elegans, this occurs during the L1 or L2 stages of larval development." .

[]
    oboInOwl:hasDbXref "GO:0007399", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000623 ;
    owl:annotatedTarget "Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000056 ;
    owl:annotatedTarget "Larvae arrest during late larval development. In C. elegans, larval arrest occurs during the L3 or L4 stages of larval development." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000624 ;
    owl:annotatedTarget "Any variation in the progression of the reproductive system over time, from its formation to its mature state compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007416", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000625 ;
    owl:annotatedTarget "Any variation in the biosynthesis of a synapse compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasExactSynonym ;
    owl:annotatedSource obo:WBPhenotype_0000625 ;
    owl:annotatedTarget "synapse development variant" .

[]
    oboInOwl:hasDbXref "GO:0046959", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000626 ;
    owl:annotatedTarget "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000000 ;
    owl:annotatedTarget "Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000627 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0051225", "WB:WBPerson2021", "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000628 ;
    owl:annotatedTarget "Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000629 ;
    owl:annotatedTarget "Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006481", "WB:WBPaper00035961", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000630 ;
    owl:annotatedTarget "Failure to execute the characteristic response to the bitter tastant quinine, as defined by control animals. In C. elegans, quinine is typically repellent." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000631 ;
    owl:annotatedTarget "Any variation in the characteristic response(s) to drug(s) as defined by control animals." .

[]
    oboInOwl:hasDbXref "GO:0007413", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000632 ;
    owl:annotatedTarget "The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised." .

[]
    oboInOwl:hasDbXref "GO:0048755", "WB:WBPaper00027335", "WB:WBPaper00027711", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000633 ;
    owl:annotatedTarget "Animals display variations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0043050", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000634 ;
    owl:annotatedTarget "Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to control." .

[]
    oboInOwl:hasDbXref "GO:0050918", "WB:cab", "WB:cgc122", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000635 ;
    owl:annotatedTarget "Any variation in the directed movement of an animal in response to chemical attractants as defined by control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000636 ;
    owl:annotatedTarget "Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000637 ;
    owl:annotatedTarget "Characteristic entry into the dauer stage is altered compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0018996", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000638 ;
    owl:annotatedTarget "Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006103", "WB:WBPerson2021", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000639 ;
    owl:annotatedTarget "Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:11813735", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000640 ;
    owl:annotatedTarget "Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control." .

[]
    oboInOwl:hasDbXref "GO:0018991" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0000640 ;
    owl:annotatedTarget "oviposition abnormal" .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000641 ;
    owl:annotatedTarget "Any variation in the degree of movement compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00006395", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000642 ;
    owl:annotatedTarget "Worms move forward or backward with an increased rate of body bends per minute compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0040011", "WB:WBPaper00024949", "WB:WBPerson712", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000643 ;
    owl:annotatedTarget "Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000644 ;
    owl:annotatedTarget "Animals do not move and are not responsive to external mechanical stimulation." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc31" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000645 ;
    owl:annotatedTarget "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000057 ;
    owl:annotatedTarget "Animals die during early larval development. In C.elegans, this occurs during the L1- L2 larval stages of the life cycle." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000646 ;
    owl:annotatedTarget "Animals move more slowly compared with control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000058 ;
    owl:annotatedTarget "Animals die during late larval development. In C. elegans, this occurs during the L3- L4 larval stages of the life cycle." .

[]
    oboInOwl:hasDbXref "GO:0007620", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000647 ;
    owl:annotatedTarget "Animals exhibit variations in any processes that lead to the successful transfer of sperm from one organism to another." .

[]
    oboInOwl:hasDbXref "GO:0060179", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000648 ;
    owl:annotatedTarget "Any variation in the specific actions or reactions of the male that are associated with reproduction compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000008 ;
    owl:annotatedTarget "Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0034608", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000649 ;
    owl:annotatedTarget "Any variation in the male's ability to locate his partner's vulva when backing along the ventral side of the partner during mating compared to control. In C. elegans the male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." .

[]
    oboInOwl:hasDbXref "GO:0030421", "WB:WBPerson2021", "WB:WBPerson557", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000650 ;
    owl:annotatedTarget "Animals exhibit variations in the processes involved in eliminating gut contents compared to control animals. In C. elegans the sequence of events during defecation includes posterior body contraction (pBoc), relaxation, anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp), and intercycle period (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000651 ;
    owl:annotatedTarget "Animals exhibit delayed or infrequent passage and/or expulsion of fecal matter." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000652 ;
    owl:annotatedTarget "Variations in the progression of a set of interacting or interdependent entities forming the sensory system over time from an initial condition to a later condition compared to control animals. The sensory system is involved in the perception of a stimuli, its conversion into a signal and the recognition and characterization of the resulting signal." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000653 ;
    owl:annotatedTarget "Variations in the progression of a set of interacting or interdependent entities forming the mechanosensory system over time from an initial condition to a later condition compared to control animals. The mechanosensory system is involved in the perception of a mechanical stimuli, its conversion into a signal and the recognition and characterization of the resulting signal." .

[]
    oboInOwl:hasDbXref "GO:0016079", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000654 ;
    owl:annotatedTarget "Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007268", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000655 ;
    owl:annotatedTarget "Animals exhibit variations in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002958", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000059 ;
    owl:annotatedTarget "The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." .

[]
    oboInOwl:hasDbXref "GO:0007268", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000656 ;
    owl:annotatedTarget "Animals exhibit variations in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000657 ;
    owl:annotatedTarget "Any variation in the process of information transfer between two neurons; usually in reference to chemical synapses, but can also be used to refer to electrical synapses compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000658 ;
    owl:annotatedTarget "Any variation in the process of communication across a synapse between a neuron and a target muscle cell compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0007631", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000659 ;
    owl:annotatedTarget "Behavior associated with the intake of food is altered compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000660 ;
    owl:annotatedTarget "Worms are found in clumps and/or crowded at the border of the bacterial lawn more frequently than control animals. This behavior is not due to mobility defects." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003187", "WB:WBPaper00032342", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000661 ;
    owl:annotatedTarget "Animals disperse across a bacterial lawn and feed alone. When food is limiting, they can aggregate into swarms or clumps, but disperse once again when food is absent." .

[]
    oboInOwl:hasDbXref "GO:0060756", "WB:WBPaper00005621", "WB:WBPaper00031455", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000662 ;
    owl:annotatedTarget "Variations in the behavior by which an organism locates food compared to control animals. In C. elegans roaming or dwelling activity on food are two examples of parameters used to assess this behavior. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000663 ;
    owl:annotatedTarget "Animals exhibit variations in the avoidance response to solutions of a particular osmotic strength compared to control. In C. elegans, animals typically avoid solutions of high osmotic strength." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000664 ;
    owl:annotatedTarget "The maximum ventral and dorsal flex of the animal is greater than that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000665 ;
    owl:annotatedTarget "Any variation that disrupts the connectivity between the somatic gonad and the adjoining tissues compared to control. In C. elegans this connnection is between the somatic gonad and the vulva in hermaphrodites and between the somatic gonad and proctodeum in males." .

[]
    oboInOwl:hasDbXref "GO:0030728", "WB:WBPaper00003017", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000666 ;
    owl:annotatedTarget "Any variation that disrupts the release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000667 ;
    owl:annotatedTarget "The specialized tissue of the reproductive tract that produces gamete is shifted from its customary place as defined by control." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000668 ;
    owl:annotatedTarget "Any variation that results in the presence of mature oocytes with distended polyploid nuclei. In C. elegans, such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000669 ;
    owl:annotatedTarget "Variations in the progression of the muscles of the adult reproductive system over time form their initial formation to their mature structure compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007283", "WB:WBPaper00027300", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000670 ;
    owl:annotatedTarget "Any variation in the processes that influence the generation and maturation of spermatozoa (motile sperm) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000671 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to copper to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027305", "WB:WBPaper00027711", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000672 ;
    owl:annotatedTarget "Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000673 ;
    owl:annotatedTarget "The number of offspring produced is altered compared to that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000674 ;
    owl:annotatedTarget "The developmental progression of an animal, from its formation to its mature structure occurs over a longer time period compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00005654", "WB:WBPaper00006395", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000060 ;
    owl:annotatedTarget "Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000675 ;
    owl:annotatedTarget "Animals die after fusion of gametes without dividing." .

[]
    oboInOwl:hasDbXref "GO:0040007", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000676 ;
    owl:annotatedTarget "The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000677 ;
    owl:annotatedTarget "Animals fail to receive, process or recognize a sensory chemical stimulus in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000678 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000679 ;
    owl:annotatedTarget "Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00005654" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasBroadSynonym ;
    owl:annotatedSource obo:WBPhenotype_0000060 ;
    owl:annotatedTarget "Adl" .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000680 ;
    owl:annotatedTarget "Animals exhibit variations in their response to aldicarb compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000681 ;
    owl:annotatedTarget "Animals exhibit variations in their response to DMPP compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:3396865" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000682 ;
    owl:annotatedTarget "Hermaphrodites are transformed into fertile females; In C. elegans, XO fog animals are somatically male but produce oocytes instead of, or in addition to, sperm." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001710", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000683 ;
    owl:annotatedTarget "The germ line is sexually transformed from hermaphrodite to male. In C. elegans, XX mog animals are somatically hermaphrodite, but germ cells that normally would become oocytes are transformed into sperm." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000684 ;
    owl:annotatedTarget "Germ cell populations are reduced compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000685 ;
    owl:annotatedTarget "Any variation that causes a reduction in growth rate during larval stages compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000686 ;
    owl:annotatedTarget "Animals exhibit variations in their response ionizing radiation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000687 ;
    owl:annotatedTarget "Both hermaphrodites and males develop into fertile females." .

[]
    oboInOwl:hasDbXref "GO:0000003", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000688 ;
    owl:annotatedTarget "Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:cab", "WB:cgc5599", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000689 ;
    owl:annotatedTarget "Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." .

[]
    oboInOwl:hasDbXref "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasExactSynonym ;
    owl:annotatedSource obo:WBPhenotype_0000689 ;
    owl:annotatedTarget "Reduced fecundity of injected worm" .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000690 ;
    owl:annotatedTarget "Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0008406", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000691 ;
    owl:annotatedTarget "Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000692 ;
    owl:annotatedTarget "X0 animals fail to generate viable cross-progeny." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001075", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000693 ;
    owl:annotatedTarget "Any perturbation that renders male derived sperm ineffective at fertilizing an oocyte." .

[]
    oboInOwl:hasDbXref "GO:0008340", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000061 ;
    owl:annotatedTarget "The duration of viability in the adult phase of the life-cycle surpasses that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000694 ;
    owl:annotatedTarget "Hermaphrodites fail to generate viable self-progeny and/or cross-progeny." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000695 ;
    owl:annotatedTarget "Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001738", "WB:WBPerson2021", "WB:WBPerson261", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000696 ;
    owl:annotatedTarget "The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004408", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000697 ;
    owl:annotatedTarget "Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001182", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000698 ;
    owl:annotatedTarget "No vulval tissue is produced. In C. elegans, this is usually a result of all six vulval precursor cells adopting a tertiary fate." .

[]
    oboInOwl:hasDbXref "GO:0040025", "WB:IA", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000699 ;
    owl:annotatedTarget "Variations in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure compared to control. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001182", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000700 ;
    owl:annotatedTarget "Multiple vulva-like protrusions are present along the ventral side of the animal. In C. elegans, this is usually a result of all six vulval precursor cells adopting primary or secondary vulval fates." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000701 ;
    owl:annotatedTarget "Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005122", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000702 ;
    owl:annotatedTarget "Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000703 ;
    owl:annotatedTarget "Variations in the form, composition or structure of the layer of cells that cover the external surface of an organism and form the inner lining between the tissues and organs of that organism and the external environment compared to control. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000704 ;
    owl:annotatedTarget "Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001109", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000062 ;
    owl:annotatedTarget "Animals die prematurely at any stage of the life cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000705 ;
    owl:annotatedTarget "Any variation in the progression of an intestinal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032168", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000706 ;
    owl:annotatedTarget "Animals lack birefringent containing compartments in embryonic intestinal cells; however, these compartments appear in adult stages." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000063 ;
    owl:annotatedTarget "Variations that cause developmental progression to cease at different stages of the lifecycle." .

[]
    oboInOwl:hasDbXref "GO:0043282", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000707 ;
    owl:annotatedTarget "Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000064 ;
    owl:annotatedTarget "Animals die prematurely at any stage of the life cycle in a sex dependent manner." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000708 ;
    owl:annotatedTarget "Variations in the progression of the intestine over time from its initial formation to its mature structure compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson363", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000065 ;
    owl:annotatedTarget "XO-bearing individuals die preferentially over other animals in the population. In C.elegans, X0 animals die preferentially over XX animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000709 ;
    owl:annotatedTarget "Variations in the form or composition of the mouthparts at the anterior end of the digestive tract which contain a series of radial muscles, related neurons and epithelial cells, and several gland cells which may aid in digestion compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson363", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000066 ;
    owl:annotatedTarget "XX-bearing individuals die preferentially over other animals in the population. In C.elegans, XX animals die preferentially over X0 animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000710 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000565", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000711 ;
    owl:annotatedTarget "Animals exhibit increased sensitivity to the effects of ion producing radiation compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000712 ;
    owl:annotatedTarget "Germ cells exhibit variations in their response to ionizing radiation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001584", "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000715 ;
    owl:annotatedTarget "Animals exhibit a greater number of embryonic muscle cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001584" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasBroadSynonym ;
    owl:annotatedSource obo:WBPhenotype_0000715 ;
    owl:annotatedTarget "Mex" .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000716 ;
    owl:annotatedTarget "Any variation in the connection of a cell whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control." .

[]
    oboInOwl:hasDbXref "GO:0010467", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000717 ;
    owl:annotatedTarget "Variations in the processes that convert a gene's sequence into a mature gene product or products (proteins or RNA), compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007549", "WB:WBPerson363" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000718 ;
    owl:annotatedTarget "Variations in the process of normalizing the expression level of X-linked genes between XX and XO animals compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000719 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000720 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000721 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000722 ;
    owl:annotatedTarget "Animals exhibit variations in the appearance of nucleoli compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0009306", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000724 ;
    owl:annotatedTarget "Variations in the regulated release of proteins from a cell or group of cells compared to control." .

[]
    oboInOwl:hasDbXref "GO:0055088", "WB:WBPaper00032000", "WB:WBPaper00032082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000725 ;
    owl:annotatedTarget "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of lipid within the organism or cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000726 ;
    owl:annotatedTarget "Any variation of the specific binding of a molecule to its partner, which typically results in a change in cell activity, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0003824", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000727 ;
    owl:annotatedTarget "Any variation in the function of naturally occurring macromolecular substances known as enzymes compared to control. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." .

[]
    oboInOwl:hasDbXref "GO:0006950", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000067 ;
    owl:annotatedTarget "Animals exhibit variations in response to stress stimuli compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0006887", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000728 ;
    owl:annotatedTarget "Variations in the process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0008219", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000729 ;
    owl:annotatedTarget "Animals exhibit variations in any of the processes that lead to the termination of vital functions of a cell." .

[]
    oboInOwl:hasDbXref "GO:0006915", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000730 ;
    owl:annotatedTarget "Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000731 ;
    owl:annotatedTarget "Germ cells exhibit increased sensitivity to the effects of ion producing radiation compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000732 ;
    owl:annotatedTarget "Variations in any process that involves the maintenance, biosynthesis or accumulation of DNA in the organism compared to control." .

[]
    oboInOwl:hasDbXref "GO:0003824", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000733 ;
    owl:annotatedTarget "Any variation in the catalysis of a biochemical reaction compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000734 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the hypodermal system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0042023", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000735 ;
    owl:annotatedTarget "Any variation in the regulated re-replication of DNA in the hypodermal cells during a single cell cycle, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0006914", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000736 ;
    owl:annotatedTarget "Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000737 ;
    owl:annotatedTarget "Germ cells fail to respond to the dosage of ion producing radiation that elicits a response in control animals. Alternatively, germ cells require a higher dosage or a longer exposure to ion producing radiation to elicit the same response as control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000738 ;
    owl:annotatedTarget "The response to a change in the environment is altered compared to control." .

[]
    oboInOwl:hasDbXref "GO:0006974", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000739 ;
    owl:annotatedTarget "Variations in the activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007049", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000740 ;
    owl:annotatedTarget "Cells of the animals exhibit variations in the initiation, progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029085", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000741 ;
    owl:annotatedTarget "Mitotic cells exhibit variations in the execution of cell-cycle arrest in response to DNA damage." .

[]
    oboInOwl:hasDbXref "GO:0034599", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000068 ;
    owl:annotatedTarget "Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0006310", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000742 ;
    owl:annotatedTarget "Variations in the process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000069 ;
    owl:annotatedTarget "Any variation in the progression of the progeny of an animal at any time from its fertilization to adulthood compared to control." .

[]
    oboInOwl:hasDbXref "GO:0016246", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000743 ;
    owl:annotatedTarget "Animals exhibit variations in their response to gene silencing triggered by double stranded RNA (RNAi), compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025139", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000744 ;
    owl:annotatedTarget "Animals exhibit variations in the silencing of endogenous genes after introduction of repetitive exogenous cognate DNA compared to control." .

[]
    oboInOwl:hasDbXref "GO:0000335", "WB:WBPaper00031962", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000745 ;
    owl:annotatedTarget "Animals exhibit variations in the activity of endogenous transposons compared to control. In C. elegans transposon activity is often measured by the rate of reversion of mutations induced by transposon insertions." .

[]
    oboInOwl:hasDbXref "GO:0051301", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000746 ;
    owl:annotatedTarget "Any variation that alters the physical partitioning and separation of a cell into daughter cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001696" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000747 ;
    owl:annotatedTarget "Any defects in the muscle contractions that control feeding. Contractions are necessary for bacterial uptake from the surrounding environment." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000748 ;
    owl:annotatedTarget "Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes)." .

[]
    oboInOwl:hasDbXref "GO:0009790", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000749 ;
    owl:annotatedTarget "Variations in the progression of an embryo over time, from zygote formation to hatching compared to control." .

[]
    oboInOwl:hasDbXref "GO:0002164", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000750 ;
    owl:annotatedTarget "Variations in the progression of a larva over time, from its formation to the mature structure compared to control. The larva is the early, immature form of an animal between hatching and adulthood." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000751 ;
    owl:annotatedTarget "Variations in the progression of a newly hatched animal through the first larval molt compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000752 ;
    owl:annotatedTarget "Variations in the progression of the second larval stage compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000753 ;
    owl:annotatedTarget "Variations in the progression of the third larval stage compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000754 ;
    owl:annotatedTarget "Variations in the progression of the fourth larval stage compared to control." .

[]
    oboInOwl:hasDbXref "GO:0018996" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000755 ;
    owl:annotatedTarget "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L1 to L2 transition." .

[]
    oboInOwl:hasDbXref "GO:0018996" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000756 ;
    owl:annotatedTarget "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L2 to L3 transition." .

[]
    oboInOwl:hasDbXref "GO:0018996" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000757 ;
    owl:annotatedTarget "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L3 to L4 transition." .

[]
    oboInOwl:hasDbXref "GO:0018996" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000758 ;
    owl:annotatedTarget "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L4 to adult transition." .

[]
    oboInOwl:hasDbXref "GO:0007051", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000759 ;
    owl:annotatedTarget "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000760 ;
    owl:annotatedTarget "The alignment of the spindle relative to other cellular structures in the cells of an embryo varies from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000761 ;
    owl:annotatedTarget "Early embryos exhibit defects in the placement or the alignment of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." .

[]
    oboInOwl:hasDbXref "GO:0051653", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000762 ;
    owl:annotatedTarget "Early embryos exhibit defects in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000763 ;
    owl:annotatedTarget "Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for an embryonic cell to carry out its normal function and activities or be able to perceive and respond to stimuli." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000764 ;
    owl:annotatedTarget "Variations in the processes that are carried out at in the embryo which results in its formation or the arrangement of constituent parts, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0051231", "WB:WBPerson2021", "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000765 ;
    owl:annotatedTarget "The embryos exhibit defects in the cell cycle process whereby the distance is lengthened between poles of the spindle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004895", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000766 ;
    owl:annotatedTarget "Any variation in the rotation of the centrosome-pronuclear complex after its migration toward the center of the embryo, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025054", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000767 ;
    owl:annotatedTarget "Sparse or enlarged yolk granules." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000768 ;
    owl:annotatedTarget "Areas devoid of yolk granules throughout the embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000769 ;
    owl:annotatedTarget "Embryos exhibit defects in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control embryos." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000770 ;
    owl:annotatedTarget "Animals exhibit variations in the appearance of embryonic cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000771 ;
    owl:annotatedTarget "Centrosomes detach from the male pronucleus." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000772 ;
    owl:annotatedTarget "Daughter nuclei are deformed and stay close to central cortex, cytokinesis defects." .

[]
    oboInOwl:hasDbXref "GO:0007059", "WB:WBPerson2021", "WB:WBPerson557", "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000773 ;
    owl:annotatedTarget "Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007276", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000774 ;
    owl:annotatedTarget "Any variation in the processes that govern the generation and maintenance of gametes compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027278", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000070 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in control males. In C. elegans, this region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan." .

[]
    oboInOwl:hasDbXref "GO:0051321", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000775 ;
    owl:annotatedTarget "Variations in the specialized nuclear and cytoplasmic divisions of a single diploid cell, whose specific outcome is the formation of four haploid daughter cells compared to control. Meiosis occurs during the formation of gametes." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc71441" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000776 ;
    owl:annotatedTarget "Male and female PNs not visible; embryo often fills egg shell completely." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000777 ;
    owl:annotatedTarget "Unextruded or resorbed polar body(ies) leading to an extra PNs in P0 and/or extra karyomeres in AB/P1." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032342", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000778 ;
    owl:annotatedTarget "Animals are unable to ingest nutrients at a rate similar to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson101" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000779 ;
    owl:annotatedTarget "Cessation of development during the final stages of embryogenesis. In C. elegans, this stage normally occurs 620-800 min after the first cleavage at 20C and is the stage after elongation." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc914" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000780 ;
    owl:annotatedTarget "Animals rotate back and forth around their longitudinal axes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000781 ;
    owl:annotatedTarget "Any variation in the extremely thin elongated cytoplasmic filament, usually composed principally of actin protein to form a myofilament lattice, as in muscle cells compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000782 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of a robust elongated cytoplasmic filament composed principally of myosin protein compared to control animals. In C. elegans, thick filaments also contain paramyosin and twitchin (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000783 ;
    owl:annotatedTarget "Animals lack the planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000784 ;
    owl:annotatedTarget "Males exhibit variations in the time of onset or duration of the fertile period owing to differences in sperm competence and/or function compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000785 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular body part compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000786 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency along a particular body axis compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000787 ;
    owl:annotatedTarget "Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the posterior body axis compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000788 ;
    owl:annotatedTarget "Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the anterior body axis compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000789 ;
    owl:annotatedTarget "Animals respond to fluoxetine at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000790 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000791 ;
    owl:annotatedTarget "The nose of an animal fails to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000792 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of the anatomy contained in the anterior region, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000793 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of the anatomy contained in the posterior region, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000794 ;
    owl:annotatedTarget "The posterior part of the worm exhibits a reduced girth compared to a control animal of the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000795 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of one of the longitudinal axes of the extended body of the worm in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000796 ;
    owl:annotatedTarget "The movement of the posterior part of the worm is not coordinated with the rest of the body." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000797 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the tail of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000798 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the head of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000799 ;
    owl:annotatedTarget "Variations in the progression of an animal's anatomy contained in the anterior region over time, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000800 ;
    owl:annotatedTarget "Variations in the progression of an animal's anatomy contained in the posterior region over time, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000801 ;
    owl:annotatedTarget "Variations in the progression of an animal's anatomy contained in the ventral region over time, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000802 ;
    owl:annotatedTarget "Variations in the progression of an animal's anatomy contained in the dorsal region over time, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000803 ;
    owl:annotatedTarget "Variations in the progression of the anterior end of the animal over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000804 ;
    owl:annotatedTarget "Variations in the progression of the overall structure or appearance of the animal over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000071 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any portion of their anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000805 ;
    owl:annotatedTarget "Any variation in the process whose specific outcome is the progression of the tail over time, from its formation to the mature structure, compared to control. The tail includes the posterior region that spans from the rectum to the end." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000806 ;
    owl:annotatedTarget "Hermaphrodites exhibit variations in the time of onset or duration of the fertile period, or variations in the production of viable offspring, including number and state of fertilized eggs laid, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000807 ;
    owl:annotatedTarget "The descendants of the G1 or G2 exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000808 ;
    owl:annotatedTarget "The descendants of the K precursor cell exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000809 ;
    owl:annotatedTarget "The descendants of a male specific precursor cell exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000810 ;
    owl:annotatedTarget "Any variation in the progression of a blast cell (precursor cell) over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000811 ;
    owl:annotatedTarget "Any variation in the progression of an epithelial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007281", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000812 ;
    owl:annotatedTarget "Variations in the progression of the immature germ cell over time, from its formation from precursors to the mature structure (gamete) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000813 ;
    owl:annotatedTarget "Any variation in the progression of a gland cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000814 ;
    owl:annotatedTarget "Any variation in the progression of a marginal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A marginal cell is a pharyngeal cell that connects the basement membrane to the apices of the triangle-shaped pharyngeal lumen." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000815 ;
    owl:annotatedTarget "Any variation in the progression of a muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000072 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0048666", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000816 ;
    owl:annotatedTarget "Variations in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000817 ;
    owl:annotatedTarget "Variations in the progression of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) over time from an initial condition to a later condition compared to control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000818 ;
    owl:annotatedTarget "Activity characteristic of an adult worm is altered compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000819 ;
    owl:annotatedTarget "Behavior characteristic of postembryonic stage(s) is altered compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000820 ;
    owl:annotatedTarget "Activity characteristic of an embryo is altered compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000821 ;
    owl:annotatedTarget "Animals exhibit variations in sex-specific behaviors compared to control." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000822 ;
    owl:annotatedTarget "Any variation in the processes that govern the sexually dimorphic development of germline or somatic tissue compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000823 ;
    owl:annotatedTarget "Nuclear divisions in the germ line are either expanded are reduced compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000824 ;
    owl:annotatedTarget "The descendants of an embryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000825 ;
    owl:annotatedTarget "The descendants of a postembryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000826 ;
    owl:annotatedTarget "The descendants of H1 or H2 cells exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000827 ;
    owl:annotatedTarget "The descendants of any of the V precursor cells (V1-V6) exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000828 ;
    owl:annotatedTarget "The descendants of TL or TR cells exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000829 ;
    owl:annotatedTarget "The descendants of Q L or QR cells exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000830 ;
    owl:annotatedTarget "The descendants of the B cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000831 ;
    owl:annotatedTarget "The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000073 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any portion of the most posterior region of the body compared to control. The anterior bound of the tail is not well defined though it might range from the position of the post-deirids to the opening of the anus (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001584", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000832 ;
    owl:annotatedTarget "The descendants of the C blastomere exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000833 ;
    owl:annotatedTarget "The descendants of the U cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000074 ;
    owl:annotatedTarget "Any variation in the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002870", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000834 ;
    owl:annotatedTarget "The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000835 ;
    owl:annotatedTarget "The descendants of the F cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000836 ;
    owl:annotatedTarget "The descendants of a gonadal precursor cell exhibit altered developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000837 ;
    owl:annotatedTarget "The descendants of a gonadal precursor cell exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000838 ;
    owl:annotatedTarget "The descendants of a gonadal precursor cell exhibit altered developmental programs in the male compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000839 ;
    owl:annotatedTarget "Z1 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000840 ;
    owl:annotatedTarget "Z4 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000841 ;
    owl:annotatedTarget "Z1 descendents exhibit altered developmental programs in the male compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000842 ;
    owl:annotatedTarget "Z4 descendants exhibit altered developmental programs in the male compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPaper00000608", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000843 ;
    owl:annotatedTarget "The number of cross progeny sired by males is reduced compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000844 ;
    owl:annotatedTarget "Pharyngeal pumping is not influenced by serotonin treatment in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000845 ;
    owl:annotatedTarget "Animals exhibit variations in the response to the addition of levamisole compared to that observed in control animals. Levamisole is a cholinergic agonist." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000846 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process in the region of the vesicle-filled varicosities of the synapse compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027305", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000847 ;
    owl:annotatedTarget "Animals display variations in the distribution of the constituents that make up the synaptic machinery such as those required for priming, docking or fusion of vesicles at the active zone, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000848 ;
    owl:annotatedTarget "The developmental progression of an animal over time, from its formation to its mature structure is delayed compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000849 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for an amphid to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000502", "WB:WBPaper00001705", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000850 ;
    owl:annotatedTarget "Animal does not respond to stroking in the anterior body region with a hair or similar fiber compared to control. In C. elegans, the anterior region is defined as the body region that lies between the posterior bulb of the pharynx and the vulva." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000851 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the ciliated neuron to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000852 ;
    owl:annotatedTarget "Variations in the progression of a free-floating spherical cell lying in the pseudocoelomic cavity of animals that can endocytose many compounds, possibly for immune surveillance, over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000075 ;
    owl:annotatedTarget "Any variation in the attachment of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) to the outer body of an animal compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0042073", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000853 ;
    owl:annotatedTarget "Variations in the bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000854 ;
    owl:annotatedTarget "Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is disrupted." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000001 ;
    owl:annotatedTarget "Animals exhibit variations in body posture compared to control animals. For example, in C. elegans characteristic sinusoidal body posture is altered." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000076 ;
    owl:annotatedTarget "Variations in the adhesion of the layer of cells that cover the external surface of an organism which serves to protect the animal from external environment compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000855 ;
    owl:annotatedTarget "Variations in the progression of the fluid-filled space which separates the body wall from internal organs over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0018996" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000077 ;
    owl:annotatedTarget "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003081" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000078 ;
    owl:annotatedTarget "The hypodermal cells, which lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, are misplaced such that they are stacked along the dorsal-ventral axis rather than forming a continuous row of adjacent cells ." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000856 ;
    owl:annotatedTarget "Any variation in the progression of a gland cell of the secretory-excretory system over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000857 ;
    owl:annotatedTarget "Variations in the progression of a protokidney cell with an internal lumen that is suggested to collect and secrete salt solutions outward via the excretory sinus, over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000858 ;
    owl:annotatedTarget "Variations in the progression of an interfacial epithelial cell which forms a lumen to receive the outflow of the excretory gland and excretory canal cells, over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000859 ;
    owl:annotatedTarget "Variations in the progression of an interfacial epithelial cell which links excretory duct to hypodermis, over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0051145", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000860 ;
    owl:annotatedTarget "Variations in the progression of muscle cells that lack transverse striations in its constituent fibers and are almost always involuntary, over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000079 ;
    owl:annotatedTarget "The small linear ridges running along the lateral lines of the cuticle of adults are branched as opposed to having an unbiforcated arrangement, lengthwise along the body (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000861 ;
    owl:annotatedTarget "Any variation in the progression of the principal muscle cell type whose contractile activity generates body motion in the nematode over time compared to control. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000862 ;
    owl:annotatedTarget "Worms appears turgid or swollen as a result of an excess number of eggs being retained in the uterus." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000863 ;
    owl:annotatedTarget "Males exhibit a reduction in the production of new individuals owing to defects in sperm competence and/or function compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027244" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000864 ;
    owl:annotatedTarget "Cessation of development during the initial period of elongation. In C. elegans, this period refers to the conversion of the bean-shaped embryo into the two-fold- shaped embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000009 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000865 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for a amphid sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000866 ;
    owl:annotatedTarget "Germ cells fail to undergo meiotic differentiation to form mature gametes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000867 ;
    owl:annotatedTarget "Cessation of development during any stage occurring after fertilization and until hatching compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000868 ;
    owl:annotatedTarget "All parts of the animal are immobilized except for the head." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000869 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000870 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000871 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000872 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "GO:0007089", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000873 ;
    owl:annotatedTarget "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G1 phase of the mitotic cell cycle just before entry into S phase, compared to control cells." .

[]
    oboInOwl:hasDbXref "GO:0000075", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000874 ;
    owl:annotatedTarget "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G2 phase of the mitotic cell cycle just before entry into M phase, nuclear division, compared to control cells." .

[]
    oboInOwl:hasDbXref "GO:0033314", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000875 ;
    owl:annotatedTarget "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the S phase of the mitotic cell cycle, which ensures DNA replication is complete, compared to control cells." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000876 ;
    owl:annotatedTarget "Animals exhibit variations in their response to osmotic stress compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000080 ;
    owl:annotatedTarget "Animals lack the anterior portion of the pharynx." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000877 ;
    owl:annotatedTarget "Any variation in the progression of a sheath cell of the amphid sensillum over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000878 ;
    owl:annotatedTarget "Any variation in the progression of a chemosensory neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "GO:0032204", "WB:WBPaper00031585", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000879 ;
    owl:annotatedTarget "Animals exhibit variations in the processes that are required to maintain the length of telomeric DNA from generation to generation compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007409", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000880 ;
    owl:annotatedTarget "Any variation in the processes that influence the generation of neuronal extensions, that carry efferent (outgoing) action potentials from the cell body towards target cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000881 ;
    owl:annotatedTarget "Animals exhibit variations in the placement of the microtuble-based dendritic projections in relation to the sensillum neuron, from that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0016358", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000882 ;
    owl:annotatedTarget "Any variation in the processes that influence the generation of neuronal extensions, that carry afferent (incoming) action potentials towards the cell body compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000883 ;
    owl:annotatedTarget "Variations in the progression of the major zone of overlapping axons in the head, which encircles the isthmus of the pharynx to form a tightly packed ring-like structure on the outside of the pharynx, over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000884 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of either of a set of two ciliated wing neurons, AWBL or AWBR, of the amphid sensilla, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0043652", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000885 ;
    owl:annotatedTarget "Any variation in the removal of a cell corpse, by a neighboring cell or a phagocyte compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000886 ;
    owl:annotatedTarget "Animals exhibit variations compared to a given control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000887 ;
    owl:annotatedTarget "Animals exhibit variations in hermaphrodite-specific behaviors compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000888 ;
    owl:annotatedTarget "Animals exhibit variations in male-specific behaviors compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003179", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000081 ;
    owl:annotatedTarget "The developmental program of the animals does not continue past the first larval stage (L1)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000889 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required to carry out sex-specific activities or to be able to perceive and respond to sex-specific stimuli compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000890 ;
    owl:annotatedTarget "Larva exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000891 ;
    owl:annotatedTarget "Adult animals appear unusually transparent when compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000892 ;
    owl:annotatedTarget "Nuclear divisions in the germ line of hermaphrodites are either expanded are reduced compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000893 ;
    owl:annotatedTarget "Nuclear divisions in the germ line of male animals are either expanded are reduced compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000894 ;
    owl:annotatedTarget "Variations in the ability of a relatively unspecialized cell to acquire the specialized features of a mature gamete compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000897 ;
    owl:annotatedTarget "Variations in the material made up of fibers forming a framework and support structure for body tissues and organs compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000898 ;
    owl:annotatedTarget "Any variation in the morphological appearance of blast cells compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000899 ;
    owl:annotatedTarget "Any variation in the morphological appearance of epithelial cells compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000900 ;
    owl:annotatedTarget "Any variation in the morphological appearance of germ cells compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000901 ;
    owl:annotatedTarget "Any variation in the morphological appearance of gland cells compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000902 ;
    owl:annotatedTarget "Any variation in the morphological appearance of intestinal cells compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000903 ;
    owl:annotatedTarget "Any variation in the morphological appearance of marginal cells compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000904 ;
    owl:annotatedTarget "Any variation in the morphological appearance of muscle cells compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000905 ;
    owl:annotatedTarget "Animals display variations in the structure or organization of components of the neuronal cell internal to the cell itself or in relation to the cellular environment compared to control. A neuron is a major cell type of nervous tissue specialized for transmission of information in the form of patterns of impulses." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000906 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) compared to control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003179", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000082 ;
    owl:annotatedTarget "The developmental program of the animals does not continue past the second larval stage (L2)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000907 ;
    owl:annotatedTarget "Any variation in the structural appearance of the caudal opening of the rectum in the tail compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000908 ;
    owl:annotatedTarget "Any variation in the structural appearance of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000909 ;
    owl:annotatedTarget "Any variation in the structure or appearance of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000910 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the rectum compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000911 ;
    owl:annotatedTarget "Any variation in the morphological appearance of coelomocytes compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000912 ;
    owl:annotatedTarget "Any variation in the morphological appearance of pericellular components compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000913 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the basal lamina compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000914 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000915 ;
    owl:annotatedTarget "Adults show deficiencies in chroma resulting in increased translucency." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000916 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the excretory cell compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000917 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the excretory duct cell compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004813", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000083 ;
    owl:annotatedTarget "The developmental program of the animals does not continue past the third larval stage (L3)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000918 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the excretory socket cell compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000461", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000919 ;
    owl:annotatedTarget "Any variation in the progression of the region of a body wall muscle cell that contains the myofilament lattice (adjacent to the hypodermis) over time, from its initial state to the fully differentiated state compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000920 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "GO:0055002", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000921 ;
    owl:annotatedTarget "Variations in the progression of muscle cells that contain fibers that are divided by transverse bands into striations, over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000922 ;
    owl:annotatedTarget "Any variation in the progression of somatic (striated) muscles that run longitudinally in males over time from its initial formation to its mature form compared to control. In C. elegans males have 3 additional sets of sex-specific longitudinal muscles (anterior and posterior outer, anterior and posterior inner, and caudal) that contribute to the body wall musculature (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000923 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the nonstriated muscle compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000924 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the striated muscle compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000925 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the sex muscles compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000926 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the body wall muscle compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000927 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the male longitudinal muscle compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000928 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required to carry out male-specific activities or to be able to perceive and respond to male-specific stimuli compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003179", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000084 ;
    owl:annotatedTarget "The developmental program of the animals does not continue past the fourth larval stage (L4)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000929 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required to carry out hermaphrodite-specific activities or to be able to perceive and respond to hermaphrodite-specific stimuli compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000930 ;
    owl:annotatedTarget "Variations in the progression of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000931 ;
    owl:annotatedTarget "Animals exhibit variations in their response to bisphenol A compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000932 ;
    owl:annotatedTarget "Animals respond to bisphenol A at a lower concentration or a shorter exposure time compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002330", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000933 ;
    owl:annotatedTarget "The descendants of the MS blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000934 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any of its parts during a given developmental stage compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026641", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000085 ;
    owl:annotatedTarget "The intestinal lumen is expanded and can often be shown to be filled with bacteria. This swelling is distinct from distension of the entire intestine (intestinal edema)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002572", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000935 ;
    owl:annotatedTarget "The descendants of the D blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000936 ;
    owl:annotatedTarget "The descendants of the P4 blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000937 ;
    owl:annotatedTarget "The descendants of the W precursor cell exhibit any variation in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000938 ;
    owl:annotatedTarget "The descendants of any of the V precursor cells (V1-V6) in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000939 ;
    owl:annotatedTarget "The descendants of TL or TR cells in male animals exhibit any variation in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000940 ;
    owl:annotatedTarget "The descendants of any of the P precursor cells (P1-P12) in male animals exhibit any variation in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000941 ;
    owl:annotatedTarget "The descendants of the M precursor cell in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000942 ;
    owl:annotatedTarget "Any variation in the progression of an accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. An accessory cell supports sensory neurons." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000943 ;
    owl:annotatedTarget "Any variation in the progression of a cluster of neuron cell bodies (somata) over time from its initial formation to its mature form compared to control." .

[]
    oboInOwl:hasDbXref "GO:0031175", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000944 ;
    owl:annotatedTarget "Variations in the progression of a neuronal extension (such as axons or dendrites) over time, from its formation to the mature structure compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000945 ;
    owl:annotatedTarget "Any variation in the progression of a dense feltwork of interwoven cytoplasmic processes of nerve cells (dendrites and axons) and support cells, over time from an initial condition to a later condition, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005941" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000086 ;
    owl:annotatedTarget "Intestine is shrunken and may appear constricted." .

[]
    oboInOwl:hasDbXref "GO:0007420", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000946 ;
    owl:annotatedTarget "Variations in the progression of a set of interacting or interdependent entities forming the pharyngeal nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000947 ;
    owl:annotatedTarget "Variations in the form, structure or composition of the material made up of fibers forming a framework and support structure for body tissues and organs compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000948 ;
    owl:annotatedTarget "Any variation in the appearance or structure of the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000949 ;
    owl:annotatedTarget "Any variation in the appearance of the body cavity compared to control. In C. elegans , an aberrancy in the psedocoelom can involve an accumulation of fluids or fluorescent reporters." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000950 ;
    owl:annotatedTarget "Any variation in the progression of a neuronal sheath cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A neuronal sheath cell is a structural cell that forms a specialized environment surrounding the sensory endings of a neuron." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000951 ;
    owl:annotatedTarget "Any variation in the progression of a socket cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000952 ;
    owl:annotatedTarget "Any variation in the progression of a cluster of neuron somata located close to the nerve ring over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000953 ;
    owl:annotatedTarget "Any variation in the progression of the ganglion that lies dorsally beside the nerve ring in the head over time from its initial formation to its mature form compared to control. In C. elegans, It contains neuron cell bodies that send their neuronal processes into the ring and longitudinal nerves, but form no local neuropil separate from the nerve ring. The dorsal ganglion is in close contact with the dorsal hypodermal cord (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000954 ;
    owl:annotatedTarget "Any variation in the progression of the ganglion which lies above and behind the rectum in the tail, in close continuity with the anal hypodermal ridge over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000955 ;
    owl:annotatedTarget "Any variation in the progression of the left and right lateral ganglia which lie beside the nerve ring in the head over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000956 ;
    owl:annotatedTarget "Any variation in the progression of the left and right lumbar ganglia which lie behind the pre-anal ganglion in the tail, in lateral positions over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000087 ;
    owl:annotatedTarget "Any variation in the progression of a body wall muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000957 ;
    owl:annotatedTarget "Any variation in the progression of the neuron somata associated with the post-deirid over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000088 ;
    owl:annotatedTarget "The arrangement of the principal muscle cell type whose contractile activity generates body motion in the nematode differs from that observed in control animals. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000958 ;
    owl:annotatedTarget "Any variation in the progression of the ganglion which lies at the posterior limit of the ventral nerve cord in the tail over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000959 ;
    owl:annotatedTarget "Any variation in the progression of the ganglion which lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000960 ;
    owl:annotatedTarget "Any variation in the progression of the ganglion which lies ventrally beside the nerve ring in the head, just anterior of the retrovesicular ganglion over time from its initial formation to its mature form compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000961 ;
    owl:annotatedTarget "Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000962 ;
    owl:annotatedTarget "Any variation in the measured expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000963 ;
    owl:annotatedTarget "Males exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000964 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of DMPP that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032243", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000965 ;
    owl:annotatedTarget "Animals exhibit variations in the programmed cell death pathway that is triggered in cells other than germ cells and that is not subject to upstream checkpoint regulation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003886", "WB:WBPaper00027026", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000966 ;
    owl:annotatedTarget "Progressive decrease in brood size culminating, over generations, in the loss of reproductive ability and thus becoming effectively sterile." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000968 ;
    owl:annotatedTarget "Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the tail compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000969 ;
    owl:annotatedTarget "Animals exhibit variations in the structure, organization or placement of the cells that support sensory neurons, compared to that observed in control animals. In C. elegans, this category collectively refers to socket cells, sheath cells, and structural cells, or their processes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000970 ;
    owl:annotatedTarget "Embryos exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals ." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000971 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the anterior body axis compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000822", "WB:WBPaper00000938", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000972 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or composition of the glia-like support cell of neuronal sensilla that ensheathes the dendrite tips and or processes of neurons, from that observed in control animals. In C. elegans, sheath cells have highly invaginated and vesiculated surfaces, which provide a specialized environment for dendritic structures." .

[]
    oboInOwl:hasDbXref "GO:0007131", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000973 ;
    owl:annotatedTarget "Animals exhibit an increased frequency of exchange of genetic material between non-sister chromatids of a pair of homologues." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000974 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required by a subset of interfacial cells to carry out its normal function or be able to perceive and respond to stimuli, compared to control. It can refer to socket cells, sheath cells and structural cells or their processes (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000089 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000975 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for a neuronal sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0007389", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000976 ;
    owl:annotatedTarget "Any variation in the developmental process that results in the creation of defined areas or spaces within the ventral cord to which cells respond and eventually are instructed to differentiate compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000977 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of the components of the gonad that are separate from the germline proper compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000978 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the spermatheca to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003371", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000979 ;
    owl:annotatedTarget "Animals exhibit defects in any physical or chemical process involved in the dilation of the distal spermatheca which is required for the oocyte exit from the gonad arm." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000980 ;
    owl:annotatedTarget "Any variation in the muscle contractions that control feeding compared to control. Contractions are necessary for bacterial uptake from the surrounding environment." .

[]
    oboInOwl:hasDbXref "GO:0048137", "WB:WBPaper00027300", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000981 ;
    owl:annotatedTarget "Animals exhibit variations in the meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids (non-motile sperm) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027300", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000982 ;
    owl:annotatedTarget "Animals exhibit variations in the ability of a relatively unspecialized spermatocyte to acquire the properties of a spermatid cell compared to control." .

[]
    oboInOwl:hasDbXref "GO:0009566", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000983 ;
    owl:annotatedTarget "Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) during sexual reproduction." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000984 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the posterior body axis compared to control." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000985 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the blast cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000090 ;
    owl:annotatedTarget "Animals are deficient in the adhesion of the cuticle to the epidermal surface of the animal." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000986 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the epithelial cell to carry out its normal functions or activities, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000987 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the germ cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000988 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the gland cell to carry out its normal functions or activities or be able to perceive and respond to signals, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000989 ;
    owl:annotatedTarget "Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for a marginal cell to carry out its normal function and activities or be able to perceive and respond to stimuli." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000990 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the muscle cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032221", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000991 ;
    owl:annotatedTarget "OBSOLETE: Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000992 ;
    owl:annotatedTarget "Failure to execute the characteristic response to high concentrations of sodium chloride solution. C. elegans typically avoids high concentrations of sodium chloride solution." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001256" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000993 ;
    owl:annotatedTarget "Animals fail to contract the anal depressor muscle." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000994 ;
    owl:annotatedTarget "Any variations in the contraction of the enteric muscles that are involved in defecation motor program compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001256", "WB:WBPaper00031246", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000996 ;
    owl:annotatedTarget "Animals exhibit defects in the expulsion of gut contents. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000997 ;
    owl:annotatedTarget "Animals tend to track and stay within low temperature environments." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000998 ;
    owl:annotatedTarget "Animals tend to track and stay within high temperature environments." .

[]
    oboInOwl:hasDbXref "WB:WBPerson363" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000999 ;
    owl:annotatedTarget "The responses of an animal towards temperature are not influenced by its cultivation temperature." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001000 ;
    owl:annotatedTarget "Any variation in the behavior characteristic during certain developmental stage(s) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001001 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of dauer stage animals in response to external or internal stimuli compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001002 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of the head muscles in response to external or internal stimuli compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001003 ;
    owl:annotatedTarget "Animals die at the L4 stage of the life cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001004 ;
    owl:annotatedTarget "Any variation in the relaxation of pharyngeal muscles after contraction events compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001005 ;
    owl:annotatedTarget "Variations in the spontaneous or induced backward crawling locomotion of an animal compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001006 ;
    owl:annotatedTarget "The number of coordinated contraction-relaxation cycles (pumps) exhibited by the pharyngeal muscle deviates from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001007 ;
    owl:annotatedTarget "Unclassified abnormality in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "GO:0007420", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001008 ;
    owl:annotatedTarget "Variations in the progression of a set of interacting or interdependent entities forming the male nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000091 ;
    owl:annotatedTarget "The cell(s) whose principal function is to provide contractile forces, is separated from the adjacent epidermis." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001009 ;
    owl:annotatedTarget "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular developmental stage of the amimal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00005654", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001010 ;
    owl:annotatedTarget "Animals appear unusually transparent when compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001011 ;
    owl:annotatedTarget "Population of unhatched eggs exhibit a complex combination of defects that do not match other class definitions." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000002 ;
    owl:annotatedTarget "The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals." .

[]
    oboInOwl:hasDbXref "GO:0006952", "WB:WBPaper00032196", "WB:WBPerson2021", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001012 ;
    owl:annotatedTarget "Animals exhibit variations in their response to disease causing agents, compared to control. Pathogen response includes prevention, damage control and recovery from the infection caused by the attack." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005370", "WB:WBPaper00024299", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001013 ;
    owl:annotatedTarget "Animals are more prone to infection compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001014 ;
    owl:annotatedTarget "Animals are less prone to infection compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001015 ;
    owl:annotatedTarget "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during any development stages compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001016 ;
    owl:annotatedTarget "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the larval stages compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001017 ;
    owl:annotatedTarget "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the adult stage compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0000910", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001018 ;
    owl:annotatedTarget "Any variation that disrupts the cytoplasmic division of a cell during embryonic development compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001019 ;
    owl:annotatedTarget "Animals arrest during the stage between early and late larval development. In C. elegans, mid larval arrest occurs during the L2 to L3 stages of development." .

[]
    oboInOwl:hasDbXref "WB:WBPerson101" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001020 ;
    owl:annotatedTarget "Animals die during the final stages of embryogenesis. In C. elegans, this lethality refers to death during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000498", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001021 ;
    owl:annotatedTarget "Genetically male animals exhibit deviations in the sexual program specific to males. In C. elegans, this often refers to XO animals being transformed into fertile hermaphrodites." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001022 ;
    owl:annotatedTarget "Genetically hermaphrodite animals exhibit deviations in the sexual program specific to hermaphrodites. In C. elegans, this refers to XX animals that develop as males or intersexuals instead of self-fertile hermaphrodites." .

[]
    oboInOwl:hasDbXref "GO:0009886", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001023 ;
    owl:annotatedTarget "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, from that observed for control animals." .

[]
    oboInOwl:hasDbXref "GO:0009886", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001024 ;
    owl:annotatedTarget "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a male in the population, from that observed for control males." .

[]
    oboInOwl:hasDbXref "GO:0009886", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001025 ;
    owl:annotatedTarget "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a hermaphrodite in the population, from that observed for control hermaphrodites." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001026 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of the membrane enclosed organelle which contains most of the cell's genetic material during the early embryonic stage compared to control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001027 ;
    owl:annotatedTarget "Embryos show defects in the placement of the nucleus to a specific location within the cell." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001028 ;
    owl:annotatedTarget "The morphological appearance of nuclei differs from control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001029 ;
    owl:annotatedTarget "Animals exhibit an uneven distribution of biochromes or any other substances that cause disparate transparency/translucency compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001030 ;
    owl:annotatedTarget "Any deficiency in the lipid bilayer, the equivalent of the nuclear envelope, that surrounds each pronucleus within gametes and within the early zygote after pronuclear reformation (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001031 ;
    owl:annotatedTarget "Any variation in the movement/fusion of pronuclei in the fertilized oocyte compared to control. For example, lack of male pronuclear migration, female pronuclear migration variable, sometimes multiple female pronuclei, no or small spindle." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000010 ;
    owl:annotatedTarget "Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001032 ;
    owl:annotatedTarget "Variations in the specific actions or reactions of a larvae in response to external or internal stimuli compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006484", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001033 ;
    owl:annotatedTarget "Any variation in the spatial pattern of proliferation and differentiation in the germ line compared to control. In C. elegans, this refers to an ectopic mass of proliferating germ cells that occupies the proximal adult germ line, a region normally occupied by gametes." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001034 ;
    owl:annotatedTarget "The morphology of pronuclei and nuclei are defective in the early embryo. In C. elegans, this defect is often characterized by pronuclei and nuclei that are small or missing altogether and are often accompanied by spindle defects." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001035 ;
    owl:annotatedTarget "The size, number and organization of the components of the nuclei in the early embryo deviate from control . In C. elegans, this is characterized by nuclei that are completely missing or are significantly smaller than normal; often accompanied by spindle and cytokinesis defects." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001036 ;
    owl:annotatedTarget "Any variation that compromises the reproductive ability of an F1 generation animal." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001037 ;
    owl:annotatedTarget "Any variation that compromises the reproductive ability of the progeny of an animal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002730", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001038 ;
    owl:annotatedTarget "Germ cells do not exit the mitotic cycle, resulting in a expansion of the unspecialized germ cell population compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001039 ;
    owl:annotatedTarget "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the embryonic stage compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0042221", "WB:WBPerson2021", "WB:cab", "WB:cgc3824" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001040 ;
    owl:annotatedTarget "Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000092 ;
    owl:annotatedTarget "Any variation in the processes that govern the expansion of intestinal cell populations compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001041 ;
    owl:annotatedTarget "Animals exhibit defects in the progression of meiosis which ultimately result in embryonic lethality." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001042 ;
    owl:annotatedTarget "Neurons show impaired ability in the detection, transmission, coordination or their response to information about an animal's internal and external environments." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001043 ;
    owl:annotatedTarget "Embryos do not enter or take longer to enter first interphase compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000093 ;
    owl:annotatedTarget "The descendants of a particular precursor cell exhibit variations in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001044 ;
    owl:annotatedTarget "Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity. In C. elegans, this is often characterized at the two-cell stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001045 ;
    owl:annotatedTarget "Pharyngeal pumping contractions are brief and occur arhythmically in response to stimulus compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001709" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001046 ;
    owl:annotatedTarget "Any variations associated with the characteristic morphology of the pharyngeal muscle such as shape, birefringence etc compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc3824" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001047 ;
    owl:annotatedTarget "Animals exhibit variations in the movement towards typically attractive water-soluble chemicals compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001048 ;
    owl:annotatedTarget "Animals exhibit variations in the chemosensory response to volatile organic compounds compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007635", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001049 ;
    owl:annotatedTarget "Variations in behavior that is dependent upon the sensation of chemicals, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007606", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001050 ;
    owl:annotatedTarget "Animals exhibit variations in any of a series of events in which an organism receives a sensory chemical stimulus, converts it to a molecular signal, and recognizes and characterizes the signal, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387", "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001051 ;
    owl:annotatedTarget "Animals exhibit variations in the characteristic movement towards typically attractive cations compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387", "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001052 ;
    owl:annotatedTarget "Animals exhibit variations in the characteristic movement towards typically attractive anions compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001053 ;
    owl:annotatedTarget "Animals exhibit variations in the characteristic movement towards cyclic nucleotides compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001054 ;
    owl:annotatedTarget "Animals fail to exhibit the same taxis behavior as control animals in response to cGMP. In C. elegans, this is characterized by the failure to move towards cGMP." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001055 ;
    owl:annotatedTarget "Animals fail to exhibit the same taxis behavior as control animals in response to bromide. In C. elegans, this is characterized by the failure to move towards bromide." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001056 ;
    owl:annotatedTarget "Animals fail to exhibit the same taxis behavior as control animals in response to iodide. In C. elegans, this is characterized by the failure to move towards iodide." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001057 ;
    owl:annotatedTarget "Animals fail to exhibit the same taxis behavior as control animals in response to lithium. In C. elegans, this is characterized by the failure to move towards lithium." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001058 ;
    owl:annotatedTarget "Animals fail to exhibit the same taxis behavior as control animals in response to potassium. In C. elegans, this is characterized by the failure of the animals to move towards potassium." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001059 ;
    owl:annotatedTarget "Animals fail to exhibit the same taxis behavior as control animals in response to magnesium. In C. elegans, this is characterized by the failure to move towards magnesium." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001060 ;
    owl:annotatedTarget "In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWC compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001061 ;
    owl:annotatedTarget "In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWA compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc1894" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001062 ;
    owl:annotatedTarget "In C. elegans, movement and elongation stop nearly simultaneously soon after the twofold stage of elongation. However, mutant embryos twitch at the one-and-a-half-fold stage of elongation, like control animals, and move as well as control animals at the two- fold stage." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:10757762", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001063 ;
    owl:annotatedTarget "Fluctuation pattern between inactive, active, and egg-laying states is atypical, based on the analysis of the distribution of the log intervals of egg-laying events compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:10757762", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001064 ;
    owl:annotatedTarget "Animals display uncharacteristically long periods during which they do not lay eggs compared to control, usually based on the analysis of the distribution of the log intervals of egg-laying events. In C. elegans, long inactive phases can be observed in HSN-ablated and serotonin-deficient animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001065 ;
    owl:annotatedTarget "Fewer egg-laying events occur within the active phase of egg laying, based on the analysis of the distribution of the log intervals of egg-laying events, compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:10757762", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001066 ;
    owl:annotatedTarget "The period during which the animal is less likely to lay eggs is not typical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001067 ;
    owl:annotatedTarget "The active phase of egg-laying, the period during which animals are more likely to display multiple egg-laying events, is atypical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000635", "WB:WBPaper00031293", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001068 ;
    owl:annotatedTarget "Animals are not induced to lay eggs in reponse to exogenous serotonin. Serotonin stimulates egg-laying in C. elegans." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001069 ;
    owl:annotatedTarget "More eggs are laid during the active phase compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001070 ;
    owl:annotatedTarget "The period during which a worm usually does not lay eggs is short compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:10757762", "pmid:9697864" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001071 ;
    owl:annotatedTarget "Activation of the active phase of egg laying is defective, leading to an abnormally long inactive phase, based on the analysis of the distribution of the log intervals of egg-laying events." .

[]
    oboInOwl:hasDbXref "GO:0032094", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001072 ;
    owl:annotatedTarget "Any variation in the state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to a food stimulus, compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:10757762" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001073 ;
    owl:annotatedTarget "Animals exhibit variations in egg-laying behavior in response to food compared to control. In C. elegans, well-fed animals lay more eggs compared with starved animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000094 ;
    owl:annotatedTarget "Any variation in the progression of the caudal opening of the rectum in the tail over time compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:14588249" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001074 ;
    owl:annotatedTarget "The vulval muscle does not respond to serotonin in the same manner as control animals. This phenotype is often assayed by imaging of calcium transients in response to serotonin." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001075 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the vulva muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001076 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways involved in the maintenance of an internal equilibrium within the vulval muscles compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001077 ;
    owl:annotatedTarget "Karyomeres in AB or P1 often accompanied by weak/thin wobbly spindle." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001078 ;
    owl:annotatedTarget "Cytokinesis is abnormal in the first or second stages of cell division." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001079 ;
    owl:annotatedTarget "Cytoplasmic movements are atypical." .

[]
    oboInOwl:hasDbXref "WB:cab", "cgc:5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001080 ;
    owl:annotatedTarget "Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001081 ;
    owl:annotatedTarget "Morphology of the cytoplasm differs from control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001082 ;
    owl:annotatedTarget "Abnormally large granules are observed in the cytoplasm of P0." .

[]
    oboInOwl:hasDbXref "WB:cab", "cgc:5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001083 ;
    owl:annotatedTarget "Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000119" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001084 ;
    owl:annotatedTarget "Failure to execute characteristic response to sodium chloride compared to control. In C. elegans, animals move towards attractive concentrations of sodium chloride." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001786" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001085 ;
    owl:annotatedTarget "Failure to execute characteristic response to butanone compared to control. In C. elegans, animals move towards typically attractive concentrations of butanone." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001786" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001086 ;
    owl:annotatedTarget "Failure to execute characteristic response to trimethylthiazole compared to control. In C. elegans, animals move towards typically attractive concentrations of trimethylthiazole." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024240" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001087 ;
    owl:annotatedTarget "Failure to execute characteristic response to acetone compared to control. In C. elegans, animals move towards typically attractive concentrations of acetone." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001088 ;
    owl:annotatedTarget "Failure to execute characteristic response to pentanol compared to control. In C. elegans, animals move towards typically attractive concentrations of pentanol." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001089 ;
    owl:annotatedTarget "Failure to execute characteristic response to hexanol compared to control. In C. elegans, animals move towards typically attractive concentrations of hexanol." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001090 ;
    owl:annotatedTarget "Animals are not able to survive at temperatures above standard cultivation temperatures to the same extent as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001091 ;
    owl:annotatedTarget "Animals exhibit variations in the elimination of fecal matter during the larval stage compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001092 ;
    owl:annotatedTarget "Animals fail to expel fecal matter during the larval stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001093 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the intestine to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001094 ;
    owl:annotatedTarget "OBSOLETE. Organismal response to NaCl differs from control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:16027367" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001095 ;
    owl:annotatedTarget "Animals respond to sodium chloride at a lower concentration or a shorter exposure compared to control animals. In C. elegans, this is often assayed through generation time and progeny number." .

[]
    oboInOwl:hasDbXref "WB:cab", "cgc:646" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001096 ;
    owl:annotatedTarget "Large protrusion at the normal position of the vulva, as seen in C. elegans lin-12 null animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:cab", "cgc:4207" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001097 ;
    owl:annotatedTarget "Unspecialized male germ cells (spermatocytes) prematurely acquire the specialized properties of functional sperm." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001423", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001098 ;
    owl:annotatedTarget "Animals lack the passage connecting the posterior intestine to the rectal valve." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001099 ;
    owl:annotatedTarget "The extreme anterior part of the body appears distorted, usually due to uncharacteristic winding." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001100 ;
    owl:annotatedTarget "Animal dies prior to the gastrulation stage of embryogenesis." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001101 ;
    owl:annotatedTarget "Characteristic response to drugs with respect to egg-laying behavior varies compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007052", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001102 ;
    owl:annotatedTarget "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a mitotic cell cycle." .

[]
    oboInOwl:hasDbXref "GO:0005819", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001103 ;
    owl:annotatedTarget "Early embryos lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001104 ;
    owl:annotatedTarget "No mitotic spindle is seen in P0." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000095 ;
    owl:annotatedTarget "The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals.  In C. elegans the M lineage is a postembryonic mesodermal lineage." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001105 ;
    owl:annotatedTarget "Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001106 ;
    owl:annotatedTarget "The orientation of the spindle is aberrant in either the AB or the P1 cell." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001107 ;
    owl:annotatedTarget "Rotation of the embryonic spindle is aberrant." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001108 ;
    owl:annotatedTarget "P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001109 ;
    owl:annotatedTarget "P0 spindle rotates late in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "GO:0005818", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001110 ;
    owl:annotatedTarget "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001111 ;
    owl:annotatedTarget "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the AB cell." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001112 ;
    owl:annotatedTarget "The morphology of the AB aster resembles that of the P1 aster in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557", "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001113 ;
    owl:annotatedTarget "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the P1 cell." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001114 ;
    owl:annotatedTarget "The progression of biochemical and morphological processes that occur during successive replication or nuclear replication events is disrupted during the early embryonic stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001115 ;
    owl:annotatedTarget "Cell cycle timing is abnormal during the first four cell divisions." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001116 ;
    owl:annotatedTarget "Absolute cell cycle timing during the first four cell divisions is aberrant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001117 ;
    owl:annotatedTarget "Cell-cell contacts are abnormal in the early embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001118 ;
    owl:annotatedTarget "Cell position is abnormal in the early embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001119 ;
    owl:annotatedTarget "Embryos take longer to divide during the first and second cell divisions." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001120 ;
    owl:annotatedTarget "Relative cell cycle timing during the first four cell divisions is aberrant." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001121 ;
    owl:annotatedTarget "Asynchrony of the second division is exaggerated and P1 divides more slowly than normal." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001122 ;
    owl:annotatedTarget "P1 divides before AB." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001123 ;
    owl:annotatedTarget "AB and P1 divide synchronously." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001124 ;
    owl:annotatedTarget "EMS divides at the same time that ABa and ABp divide." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001125 ;
    owl:annotatedTarget "P2 and EMS divide synchronously." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001126 ;
    owl:annotatedTarget "Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001127 ;
    owl:annotatedTarget "The EMS blastomere fails to extend anteriorly and make extensive contact (hug) with the ABa blastomere." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001128 ;
    owl:annotatedTarget "EMS extends too far anteriorly at the four cell stage." .

[]
    oboInOwl:hasDbXref "GO:0032154", "WB:WBPerson2021", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001129 ;
    owl:annotatedTarget "Embryos exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001130 ;
    owl:annotatedTarget "Cells of the embryo attempt to divide but fail to form two daughter cells." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001131 ;
    owl:annotatedTarget "Once formed, the mitotic furrow can \"slide\"laterally." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001132 ;
    owl:annotatedTarget "One or more extra cleavage furrows are seen in one or more cells of a one-cell to four-cell embryo" .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001133 ;
    owl:annotatedTarget "The cell division axis is not normal." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001134 ;
    owl:annotatedTarget "ABa or ABp divide in the wrong orientation." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001135 ;
    owl:annotatedTarget "Animals exhibit defects in the form, structure or composition of any of its parts during the early embryonic stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001136 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any of its parts during any developmental stage ranging from zygote formation to hatching compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005599", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001137 ;
    owl:annotatedTarget "Embryos are produced that are less than fifty percent of the size of control embryos." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001138 ;
    owl:annotatedTarget "Nucleus is abnormal in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001139 ;
    owl:annotatedTarget "Nuclear envelope does not reassemble properly." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001140 ;
    owl:annotatedTarget "Any variation in the normal orderly movement of neurons from one site to another compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001141 ;
    owl:annotatedTarget "After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000096 ;
    owl:annotatedTarget "Variations in the progression of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) over time compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001142 ;
    owl:annotatedTarget "Nuclear number is abnormal in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001143 ;
    owl:annotatedTarget "Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001144 ;
    owl:annotatedTarget "Defects are either seen in the number or size of the polar bodies in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001145 ;
    owl:annotatedTarget "Polar body number is abnormal in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001146 ;
    owl:annotatedTarget "Polar body size is abnormal in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001147 ;
    owl:annotatedTarget "Polar bodies are abnormal in the inviable one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001148 ;
    owl:annotatedTarget "Polar body is reabsorbed in the one- to four-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001149 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001150 ;
    owl:annotatedTarget "A polar body is reabsorbed in either the one cell- or the two-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001151 ;
    owl:annotatedTarget "Pronucleus is abnormal in the inviable embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001152 ;
    owl:annotatedTarget "Pronucleus migration is abnormal in the inviable embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001153 ;
    owl:annotatedTarget "Neither of the pronuclei migrate and they never meet." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001154 ;
    owl:annotatedTarget "Instead of the maternal pronucleus migrating to the posterior end of the one-cell embryo, the paternal pronucleus migrates to meet the maternal pronucleus in the anterior end." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001155 ;
    owl:annotatedTarget "The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001156 ;
    owl:annotatedTarget "Maternal or paternal pronucleus is either too small or too large." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001157 ;
    owl:annotatedTarget "Pronuclear breakdown is atypical in the inviable embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001158 ;
    owl:annotatedTarget "Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001159 ;
    owl:annotatedTarget "Pronucleus morphology is atypical in the inviable embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001160 ;
    owl:annotatedTarget "Morphology of the pronuclear envelope is atypical in the inviable embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001161 ;
    owl:annotatedTarget "Maternal pronucleus has a blurry appearance. The nuclear envelope does not have a crisp circular shape." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001162 ;
    owl:annotatedTarget "There are more than two pronuclei in the inviable embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001163 ;
    owl:annotatedTarget "Either the maternal or paternal pronucleus is absent." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001164 ;
    owl:annotatedTarget "There is either more than one maternal or paternal pronucleus in the inviable embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001165 ;
    owl:annotatedTarget "One-cell embryos have two or more maternal pronuclei." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001166 ;
    owl:annotatedTarget "More than one paternal pronucleus is present in the inviable one-cell embryo or there is a defect in centrosome structure." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1815", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001167 ;
    owl:annotatedTarget "Pseudocleavage is atypical in the inviable one-cell embryo." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001168 ;
    owl:annotatedTarget "No pseudocleavage is observed before or during pronuclear migration." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001169 ;
    owl:annotatedTarget "Embryos have more pronounced pseudocleavage than normal." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001170 ;
    owl:annotatedTarget "Injected worm stops producing embryos 48 hours after RNAi injection and contains no live/developing embryos at this time." .

[]
    oboInOwl:hasDbXref "GO:0008340", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001171 ;
    owl:annotatedTarget "The duration of viability in the adult phase of the life-cycle is less than that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001172 ;
    owl:annotatedTarget "Developmentally regulated termination of a cell or cell group does not occur as in control animals." .

[]
    oboInOwl:hasDbXref "GO:0008219", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001173 ;
    owl:annotatedTarget "Animals exhibit variations in the specific activation or halting of processes within a cell that occur through necrosis or programmed cell death pathways different from apoptosis, so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001174 ;
    owl:annotatedTarget "Chromosomes fail to segregate away from their homolog, resulting in gametes with no or extra copies of the chromosome." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004402", "WB:WBPaper00005654", "WB:WBPerson712", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001175 ;
    owl:annotatedTarget "Higher numbers of male progeny occur in the population compared to control populations. In C. elegans, the high incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an increase in X chromosome nondisjunction." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001176 ;
    owl:annotatedTarget "One-cell embryos have an altered shape." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001177 ;
    owl:annotatedTarget "Embryos rupture when placed on a 2% agar pad and covered with a coverslip." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001178 ;
    owl:annotatedTarget "The structure of the egg is impaired, flawed or no longer intact." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001179 ;
    owl:annotatedTarget "OBSOLETE. Phenotypic examination of worms did not reveal an obvious abnormality compared with control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001180 ;
    owl:annotatedTarget "Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001181 ;
    owl:annotatedTarget "Animals exhibit an increase in the quantity of non-germ line cells that have undergone programmed cell death but have not been engulfed." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001584", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000097 ;
    owl:annotatedTarget "The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "GO:0019915", "WB:WBPaper00032082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001182 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of fat or lipids present in the organism compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0019915", "WB:WBPaper00032082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001183 ;
    owl:annotatedTarget "Animals exhibit less fat or lipid than observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0019915", "WB:WBPaper00032082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001184 ;
    owl:annotatedTarget "Animals exhibit a greater amount of fat or lipids than observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001185 ;
    owl:annotatedTarget "The developmental progression of an early embryo over time, from its formation to its mature structure is delayed compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5599" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001186 ;
    owl:annotatedTarget "Embryos are either delayed or arrested at pronuclear contact." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001187 ;
    owl:annotatedTarget "EMS divides before P2." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026850", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001188 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of radial arrangement of actin within the pharyngeal muscle compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026850", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001189 ;
    owl:annotatedTarget "Any variation in the cell junctions of the pharyngeal muscle at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001190 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the pharynx to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001191 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for muscles in the pharynx to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001192 ;
    owl:annotatedTarget "Any variation in the series of molecular signals in which a pharyngeal cell uses calcium ions to convert an extracellular signal into a response, compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7545" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001193 ;
    owl:annotatedTarget "Electropharyngeograms do not show a similar pattern as control animals. C. elegans animals show a repeating regular pattern in which each pump is associated with an excitatory depolarizing wave, often punctuated by brief negative spikes, followed by a plateau phase, and ending with an inhibitory hyperpolarizing wave." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027335", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001194 ;
    owl:annotatedTarget "Animals have one or more extra neurons, which are present in places they are normally not found, when compared to the number and location of these neurons in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc4194", "WB:cgc7545" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001195 ;
    owl:annotatedTarget "Rhythmic calcium increases in the pharynx are observed less often than in control animals. In C. elegans, rhythmic increases in intracellular calcium are often observed using a transgenically expressed cameleon, a ratiometric calcium indicator." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7545" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001196 ;
    owl:annotatedTarget "Calcium spikes lack synchrony in the musculature of the corpus and the terminal bulb as seen in control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001197 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic gonad to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001198 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic sheath system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001199 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the contraction of a thin continuous tube surrounding the proximal portions of the ovary and covering the maturing oocytes to the near portion of the distal gonad arm, compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7545" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001200 ;
    owl:annotatedTarget "Basal contraction rate and or peak contraction rate of the gonadal sheath is reduced relative to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001201 ;
    owl:annotatedTarget "Animals lack the stereotyped muscle contractions that result in the opening of anus." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:cab", "WB:cgc7388" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001202 ;
    owl:annotatedTarget "Animals respond to nicotine at lower concentrations or shorter exposure compared to control. Nicotine is a cholinergic agonist." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000098 ;
    owl:annotatedTarget "Any variation in the progression of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine over time compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:cab", "WB:cgc7388" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001203 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of nicotine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001204 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of muscimol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001205 ;
    owl:annotatedTarget "Animals respond to muscimol at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001206 ;
    owl:annotatedTarget "Variations in the process by which an organism travels from one location to another compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001207 ;
    owl:annotatedTarget "Any variation in a series of protein mediated signals that help relay information within the cell, and thereby affecting changes in the functioning of the cell, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001208 ;
    owl:annotatedTarget "Animals show reduced susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026735", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001209 ;
    owl:annotatedTarget "Apparently normal sinusoidal movement, but appear to have poor traction on the agar surface of a culture plate." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001210 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process taking place in extracellular spaces within or associated with the organism, from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001211 ;
    owl:annotatedTarget "The physical strength or function of the cuticle varies from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001212 ;
    owl:annotatedTarget "The strength of the cuticle is less robust than that observed for control animals. In C. elegans the strength of the cuticle is often assayed by it's ability to protect the animal from exposure to bleach or other compounds." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001213 ;
    owl:annotatedTarget "Animals exhibit a decrease in any parameter used to measure locomotion compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001214 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001007", "WB:WBPaper00005486", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001215 ;
    owl:annotatedTarget "Variations in the mitotic expansion of germ cell populations or in the appearance of nuclei during development in the premeiotic region of the germline compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:11134076" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001216 ;
    owl:annotatedTarget "Oocyte chromosomes arrest in metaphase of meiosis I without transitioning to anaphase or producing polar bodies." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001217 ;
    owl:annotatedTarget "Germ line cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001218 ;
    owl:annotatedTarget "Animals exhibit variations in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001219 ;
    owl:annotatedTarget "Animals exhibit a decrease in the rate or extent of programmed cell death and thus an increase in cell survival, as it pertains to a sex-specific feature, compared to control populations." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001220 ;
    owl:annotatedTarget "Animals exhibit in increase in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001705", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001221 ;
    owl:annotatedTarget "Animal fails to exhibit characteristic response after a nose-on collision with an object compared to control. In C. elegans, this is usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001222 ;
    owl:annotatedTarget "Animals exhibit an increase in frequency of transposition events (DNA movement to different positions within the genome of a single cell) causing an accumulation of lesions within the genome, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001223 ;
    owl:annotatedTarget "Animals show reduced susceptibility to gene silencing in the germline triggered by double stranded RNA (RNAi), compared to control." .

[]
    oboInOwl:hasDbXref "GO:0048675", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001224 ;
    owl:annotatedTarget "Any variation in the processes that govern the extension of axons compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938", "WB:WBPaper00004350", "WB:WBPaper00026656", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001225 ;
    owl:annotatedTarget "Animals are missing the interfacial hypodermal cell (socket cell) of the phasmid sensillum pore." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938", "WB:WBPaper00001576", "WB:WBPaper00029065", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001226 ;
    owl:annotatedTarget "Animals display variations in the structure, organization or path of the part of the axon that forms a bridge between body regions, compared to that in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027335", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001227 ;
    owl:annotatedTarget "Animals are missing any one of its commissures, an axon tract that connects one body part to another." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001228 ;
    owl:annotatedTarget "Animals lack the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001229 ;
    owl:annotatedTarget "The orderly movement of neurons along the anterior axis of the animal is abolished, misdirected or incomplete compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001230 ;
    owl:annotatedTarget "The orderly movement of cells along the anterior axis of the animal is abolished, misdirected or incomplete compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001231 ;
    owl:annotatedTarget "The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is increased compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001232 ;
    owl:annotatedTarget "Animals exhibit variations in the response to the addition of serotonin compared to that observed in control animals. Serotonin is a monoamine neurotransmitter." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000099 ;
    owl:annotatedTarget "The descendants of any of the P precursor cells exhibit variations in developmental programs compared to their counterparts in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001233 ;
    owl:annotatedTarget "Animals exhibit variations in the pattern of a chemical nuclear stain which is commonly used in fixed specimens and produces a bright blue label, compared to control. DAPI (4'-6-Diamidino-2-phenylindole) forms fluorescent complexes with natural double-stranded DNA (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002917" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001234 ;
    owl:annotatedTarget "Failure to execute the characteristic response to nonanone compared to control. In C. elegans, nonanone is a repellant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001235 ;
    owl:annotatedTarget "Any variation in the orientation of the physical partitioning and separation of a cell into daughter cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001236 ;
    owl:annotatedTarget "Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." .

[]
    oboInOwl:hasDbXref "GO:0030517", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001237 ;
    owl:annotatedTarget "Any perturbation that causes an increase in the frequency of axon outgrowth compared to control. As a result, an excess number of axonal projections are generated." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:16624900" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001238 ;
    owl:annotatedTarget "Any variation in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva." .

[]
    oboInOwl:hasDbXref "pmid:16624900" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001239 ;
    owl:annotatedTarget "Any increase in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001240 ;
    owl:annotatedTarget "Variations in the processes leading to the specialization of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001242 ;
    owl:annotatedTarget "The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is lower compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001243 ;
    owl:annotatedTarget "The bidirectional transport of molecules (cargo) along axonemal microtubules is reduced compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001244 ;
    owl:annotatedTarget "Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is completely abolished." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001245 ;
    owl:annotatedTarget "The bidirectional transport of molecules along the middle segment of axonemal microtubules of the cilia is absent." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001246 ;
    owl:annotatedTarget "The bidirectional transport of molecules along the distal segment of axonemal microtubules of the cilia is absent." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001247 ;
    owl:annotatedTarget "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons is disrupted." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPaper00029016", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001248 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of the microtuble-based projections that in control animals invaginate individually into the sheath cell of the neuronal sensillum rather than projecting through the socket cell to the outside. In C. elegans, the cilia of each wing cell has its own unique shape and as they are not exposed to the outside, they do not typically take up dyes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001249 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or composition of the dendritic projections of the amphid sensory neurons that traverse the sensillum pore to connect with the outside of the animal, compared to that observed in control animals. In C. elegans, amphid channel cilia morphology is frequently assayed by dye-filling experiments using FITC, DiI or DiO." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001250 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or composition of the microtuble-based fibrillar core, axoneme, of the cilia of the neurons that project through the sensillum pore to the outside of the animal, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPaper00027116", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001251 ;
    owl:annotatedTarget "The microtuble-based fibrillar-bundles of the amphid sensory cilia are reduced in length compared to those in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001252 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of the microtubule-based fibrillar section, axoneme, of the cilia of the flat sheet-like cells associated with sensory function, from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001253 ;
    owl:annotatedTarget "The microtuble-based fibrillar-bundle, axoneme, of the wing cell cilia are reduced in length and do not extend into the sheath cell as far as they do in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027116", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001254 ;
    owl:annotatedTarget "The dendritic processes that normally extend through the amphid sensillum pore to the outside are truncated and have swollen ends as opposed to the extended and finger-like tips of channel cilia in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027116", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001255 ;
    owl:annotatedTarget "Animals exhibit wing cell sensory cilia that are truncated and swollen unlike that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001256 ;
    owl:annotatedTarget "Variations in the aggregation of molecules at the site of DNA strand breakage or damage compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001257 ;
    owl:annotatedTarget "Variations in the generation of foci that mark sites of aberrant bonding of molecules to the DNA strand, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001258 ;
    owl:annotatedTarget "Animals show increased susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001259 ;
    owl:annotatedTarget "Hermaphrodites exhibit a reduction in the production of new individuals owing to defects in gamete competence and/or function compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000100 ;
    owl:annotatedTarget "Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001883", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001260 ;
    owl:annotatedTarget "Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001261 ;
    owl:annotatedTarget "Animals show deficiencies in chroma resulting in increased translucency." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000101 ;
    owl:annotatedTarget "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, UV irradiation, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001262 ;
    owl:annotatedTarget "The developmental progression of the egg-laying organ of female and hermaphrodite nematodes is halted prior to the formation of the mature structure." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001263 ;
    owl:annotatedTarget "The morphological appearance of peroxisomes is variant compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001264 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the peroxisome to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000214" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001265 ;
    owl:annotatedTarget "The anterior portion of the animal exhibits variations in its movement compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001266 ;
    owl:annotatedTarget "Any variation in triggering of the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001267 ;
    owl:annotatedTarget "Any variation in the frequency of gonad sheath contractions triggered by internal or external stimuli compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001268 ;
    owl:annotatedTarget "Animals exhibit variations in the extent of activation of programmed cell death, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001269 ;
    owl:annotatedTarget "Animals exhibit variations in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001270 ;
    owl:annotatedTarget "Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001271 ;
    owl:annotatedTarget "Animals are more prone to lethality as a result of infection compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001272 ;
    owl:annotatedTarget "Vulval precursor cells inappropriately adopt fates that are normally restricted to other vulval precursor cells compared to control." .

[]
    oboInOwl:hasDbXref "GO:0009408", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001273 ;
    owl:annotatedTarget "Any variation in the state or activity of an organism (in terms of movement, gene expression, etc.) in response to heat (high temperatures above the optimal temperature for that organism), compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001274 ;
    owl:annotatedTarget "Animals respond to heat at a lower temperature or a shorter exposure time compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001275 ;
    owl:annotatedTarget "Any variation that increases the magnitude of a signal generated by a set of gene interactions in a given pathway, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001276 ;
    owl:annotatedTarget "Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001277 ;
    owl:annotatedTarget "XX animals are transformed into males or pseudomales ." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001278 ;
    owl:annotatedTarget "Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001279 ;
    owl:annotatedTarget "Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the male, that has been introduced into the organism compared to its expression in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001280 ;
    owl:annotatedTarget "Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the hermaphrodite, that has been introduced into the organism compared to its expression in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001281 ;
    owl:annotatedTarget "Pharynx becomes clogged with food. In C. elegans, this is often a result of pharyngeal pumping defects." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001282 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways of the mitochondria compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000004 ;
    owl:annotatedTarget "Eggs are laid under conditions where egg laying is normally inhibited." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001283 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways of an organelle compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001284 ;
    owl:annotatedTarget "Animals contain a lower level of coenzyme Q, an oil-soluble vitamin-like substance present in most eukaryotic cells, primarily in the mitochondria, compared to control. It is a component of the electron transport chain and participates in aerobic cellular respiration." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001285 ;
    owl:annotatedTarget "Pharyngeal pumping is not influenced by treatment with specific compounds (eg: serotonin) in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001286 ;
    owl:annotatedTarget "Exposure to food does not reduce pharyngeal pumping to the same extent as observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001287 ;
    owl:annotatedTarget "Animals do not exhibit a decrease in pumping rate when treated with specific compounds (such as pheromones) as is observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027305" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000102 ;
    owl:annotatedTarget "Animals display variations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001289 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of acetylcholinesterase inhibitor that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001290 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a specific acetylcholinesterase inhibitor compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0035176", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001291 ;
    owl:annotatedTarget "Animals exhibit variations in actions and responses that occurs predominantly, or only, in individuals that are part of a group, from that observed for animals in a control group." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001292 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the body wall muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001293 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the larva to carry out its normal metabolic functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000031" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001294 ;
    owl:annotatedTarget "The most anterior portion of the animal is not aligned with the axis of the body." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001295 ;
    owl:annotatedTarget "Any portion of the animal, between the head and the tail, appears distorted, usually due to uncharacteristic winding." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001296 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of lannate that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001297 ;
    owl:annotatedTarget "Any variation in the process whose specific outcome is the progression of the male tail over time, from its formation to the mature structure, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001298 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of the more posterior portion of the intestine, just anterior to the sphincter valve, which is subject to squeezing by the somatal-intestinal muscles compared to control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001299 ;
    owl:annotatedTarget "Any variation that alters the physical partitioning and separation of a cell into daughter cells in male animals compared to control." .

[]
    oboInOwl:hasDbXref "GO:0005737", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001300 ;
    owl:annotatedTarget "Any variation in the composition or structure of the contents within a germ cell, excluding the plasma membrane and nucleus, compared to control. Germ cells include sperm, oocytes, and their precursors." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:11262230" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001301 ;
    owl:annotatedTarget "Localization or structural appearance of P-granules is altered compared to control. P-granules are cytoplasmic structures associated with germ nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell precursors, throughout the life cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001477", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001302 ;
    owl:annotatedTarget "The restricted localization of P granules to germ cells or germ cell precursors is altered compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001303 ;
    owl:annotatedTarget "Animals have one or more extra cells of a particular type, which are present in places they are normally not found, when compared to the number and location of these cells in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000011 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003719", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001304 ;
    owl:annotatedTarget "The terminal portion of the intestine exhibits structural defects such as scarring or blockage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001305 ;
    owl:annotatedTarget "Any variation in the form or composition of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001306 ;
    owl:annotatedTarget "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the male reproductive system compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001307 ;
    owl:annotatedTarget "The maximum ventral and dorsal flex of the animal is reduced compared to that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001308 ;
    owl:annotatedTarget "The contraction and relaxation movements of the pharyngeal muscle that mediate feeding is not as robust as compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2021", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001309 ;
    owl:annotatedTarget "Animals exhibit a decrease in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001310 ;
    owl:annotatedTarget "The placement of neuronal cells, as a whole or of a specific class of neuron in the animal, deviates from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000103 ;
    owl:annotatedTarget "Any variation in the progression of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes over time compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001311 ;
    owl:annotatedTarget "Variations that result in a decrease in protein expression in hermaphrodites compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027711", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001312 ;
    owl:annotatedTarget "The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001313 ;
    owl:annotatedTarget "Any variation in the progression of the sex-specific muscles of the hermaphrodite, over time, whose contractions squeeze on the uterus to help move eggs towards the vulval opening compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001314 ;
    owl:annotatedTarget "Any variation in the progression of the sex-specific muscles in the hermaphrodite, over time, that are specialized for egg-laying compared to control. In C. elegans the contractions of the vulval muscles open the lips of the vulva to help in expelling an egg from the uterus (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001315 ;
    owl:annotatedTarget "Animals exhibit variations in the electrical properties of any of its cells or tissues compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "pmid:14735116" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001316 ;
    owl:annotatedTarget "Variations in the synaptic currents that are elicited by firing an action potential in a population of axons, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001317 ;
    owl:annotatedTarget "The amplitudes of synaptic currents that are elicited by firing an action potential in a population of axons are decreased, compared to those observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "pmid:14735116" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001318 ;
    owl:annotatedTarget "Any variation in the currents observed in the absence of presynaptic action potentials and that are elicited by fusion of a single endogenous vesicle of transmitter compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026938", "WB:WBPerson2021", "pmid:14735116" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001319 ;
    owl:annotatedTarget "The rate (frequency) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is decreased compared to control. Changes in frequency are indicative of presynaptic modifications." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "pmid:14735116" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001320 ;
    owl:annotatedTarget "The amplitude (magnitude) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is altered compared to control. Changes in amplitude are often interpreted as alterations of postsynaptic responsiveness to the transmitter." .

[]
    oboInOwl:hasDbXref "GO:0042734", "WB:WBPaper00000938", "WB:WBPaper00027305", "WB:WBPaper00028886", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001321 ;
    owl:annotatedTarget "Animals display variations in the structure, configuration, distribution or ratio of the components of the vesicle-filled varicosities of the synapse compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:16803962" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001322 ;
    owl:annotatedTarget "OBSOLETE. Total presynaptic vesicle number is reduced, possibly refecting a defect in the replenishment of synaptic vesicles compared to control." .

[]
    oboInOwl:hasDbXref "GO:0031982", "WB:WBPaper00027612", "WB:WBPaper00027711", "WB:WBPerson712", "WB:cab", "pmid:16803962" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001323 ;
    owl:annotatedTarget "Animals display variations in the shape or size of their vesicles, which are spherical, membrane-bound fluid-filled organelles, compared to vesicles observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001324 ;
    owl:annotatedTarget "Cells exhibit variations in their response to ionizing radiation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc914" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001325 ;
    owl:annotatedTarget "Animals initiate but do not continue backward movement, similar to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001326 ;
    owl:annotatedTarget "Cells exhibit variations in their response to gamma ray radiation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001327 ;
    owl:annotatedTarget "Cells respond to a lower dosage of gamma rays or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001328 ;
    owl:annotatedTarget "The posterior part of the worm is shorter and stouter compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc914" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001329 ;
    owl:annotatedTarget "Animals exhibit a greater number of bends in their body compared to control. C. elegans posture assumes more than a single sine wave." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000012 ;
    owl:annotatedTarget "Formation of dauer larvae under conditions that do not favor dauer formation." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001330 ;
    owl:annotatedTarget "The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate is reduced compared to that observed in control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031356", "WB:WBPerson2021", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000104 ;
    owl:annotatedTarget "Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001331 ;
    owl:annotatedTarget "Animals display variations in the structure or organization of components of the motor neuron, internal to the cell itself or in relation to the cellular environment compared to that observed in control animals. A motor neuron is a neuronal cell that synapses to an effector (muscle, gland etc.)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001332 ;
    owl:annotatedTarget "Animals display variations in the number of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000502", "WB:WBPaper00000635", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001333 ;
    owl:annotatedTarget "The body of a neuron is not where it should be when compared to control animals; it is absent or misplaced." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001334 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the muscles of the adult hermaphrodite reproductive system compared to control. In C. elegans hermaphrodites these muscles include the vulval and uterine muscles, located near the vulva in the midbody, which all derive from the M myoblast (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001335 ;
    owl:annotatedTarget "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the hermaphrodite reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPaper00000608", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001336 ;
    owl:annotatedTarget "Males sire no cross progeny." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001337 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a specific adrenergic receptor antagonist compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001338 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of phentolamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000635", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001339 ;
    owl:annotatedTarget "Animals are not induced to lay eggs in reponse to exogenous levamisole. In C. elegans, levamisole stimulates egg-laying." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000635", "WB:WBPaper00001133", "WB:WBPaper00031293", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001340 ;
    owl:annotatedTarget "Animals are not induced to lay eggs in reponse to exogenous imipramine. In C. elegans, imipramine stimulates egg-laying." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000635", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001341 ;
    owl:annotatedTarget "Animals are not induced to lay eggs in reponse to exogenous phentolamine. In C. elegans, phentolamine stimulates egg-laying." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000635", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001342 ;
    owl:annotatedTarget "Animals respond to exogenous imipramine at a lower concentration or within a shorter time period than control animals under the same conditions." .

[]
    oboInOwl:hasDbXref "GO:0000212", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001343 ;
    owl:annotatedTarget "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a meiotic cell cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032168", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001344 ;
    owl:annotatedTarget "Intracellular membrane bound compartments vary in shape or size from that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0005856", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001345 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." .

[]
    oboInOwl:hasDbXref "GO:0031532", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001346 ;
    owl:annotatedTarget "Any variation in the dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001347 ;
    owl:annotatedTarget "Any variation in the series of molecular signals in which an intestinal cell uses calcium ions to convert an extracellular signal into a response, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001348 ;
    owl:annotatedTarget "Variations in the form or composition of a structure in the cell nucleus which contains the genetic material encoded as DNA and surrounded by histone proteins and other regulatory elements compared to control. In C. elegans the normal cell contains 5 pairs of 'autosomes' and one or two X chromosomes (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0006468", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001349 ;
    owl:annotatedTarget "Variations in the processes that incorporate phosphate groups to one or more amino acids within a protein, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0001556", "WB:WBPaper00026997", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000105 ;
    owl:annotatedTarget "Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001350 ;
    owl:annotatedTarget "Animals exhibit higher levels of protein phosphorylation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001351 ;
    owl:annotatedTarget "Animals exhibit decreased levels of protein phosphorylation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001352 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways of the endoplasmic reticulum compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027230", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001353 ;
    owl:annotatedTarget "The coordinated movement during prophase of the two centrosomes and the two pronuclei towards the center of the one cell embryo is abolished." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001354 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001355 ;
    owl:annotatedTarget "Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001356 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the muscles of the adult male reproductive system compared to control. In C. elegans males, the M myoblast gives rise to a much larger set of specialized muscles, compared to hermaphrodites, which differentiate within the tail region (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001357 ;
    owl:annotatedTarget "Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male gametes compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001358 ;
    owl:annotatedTarget "Male animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027278", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001359 ;
    owl:annotatedTarget "Animals exhibit variations in the structure and organization of the chamber in the male tail that extends from the termination of four canals (vas deferens, gut, and left and right spicule channels) to just before the cloaca, from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001075", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001360 ;
    owl:annotatedTarget "Hermaphrodites fail to produce any viable progeny via self-fertilization. However, such hermaphrodites can successfully reproduce if mated to control males." .

[]
    oboInOwl:hasDbXref "GO:0030261", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001361 ;
    owl:annotatedTarget "Any variation in the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003371", "WB:WBPaper00026997", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000106 ;
    owl:annotatedTarget "Variations in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0030261", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001362 ;
    owl:annotatedTarget "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis in eukaryotic cells is abolished." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001363 ;
    owl:annotatedTarget "The head contains cavities, possibly indicative of inappropriate cell death." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001364 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the flattened structure extending laterally at the extreme tip of the adult male consisting of nine pairs of sensory rays that lie within a web-like cuticle compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001365 ;
    owl:annotatedTarget "Any variation in the process whose specific outcome is the progression of the male bursa over time, from its formation to the mature structure, compared to control. The male bursa consists of the lateral fan and rays (WormAtlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001366 ;
    owl:annotatedTarget "Any variation in the process whose specific outcome is the progression of the male fan over time, from its formation to the mature structure, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001367 ;
    owl:annotatedTarget "Any variation in the process whose specific outcome is the progression of the male proctodeum over time, from its formation to the mature structure, compared to control. The union of the vas deferens and the intestine give rise to the proctodeum which contains copulatory spicules." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001368 ;
    owl:annotatedTarget "Animals lack the somatic gonad structure that connects the distal gonad arm to the uterus." .

[]
    oboInOwl:hasDbXref "GO:0005515", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001369 ;
    owl:annotatedTarget "Variations in the selective and non-covalent physical association between two or more proteins, or a protein and nucleic acid/macromolecular complex, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001370 ;
    owl:annotatedTarget "Variations in the selective and non-covalent physical association between two or more proteins, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001371 ;
    owl:annotatedTarget "Variations in the selective and non-covalent physical association between a protein and a specific RNA sequence, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001372 ;
    owl:annotatedTarget "Variations in the selective and non-covalent physical association between a protein and a specific DNA sequence, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001373 ;
    owl:annotatedTarget "Animals lack a specific protein-RNA interaction observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028895", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001374 ;
    owl:annotatedTarget "The shape and size of nuclei as well as the distribution of nucleoporins are strongly affected." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001375 ;
    owl:annotatedTarget "The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001376 ;
    owl:annotatedTarget "The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection in specific cells." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032296", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001377 ;
    owl:annotatedTarget "Variations in the generation of foci that mark crossover recombination events, compared to control. These foci mark the boundary of asymmetric synaptonemal complex disassembly." .

[]
    oboInOwl:hasDbXref "GO:0000070", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001378 ;
    owl:annotatedTarget "Any variation in the cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0060280", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000107 ;
    owl:annotatedTarget "Any variation that alters the control mechanisms that inhibit oocyte maturation and release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001379 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a specific toxic chemical compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001380 ;
    owl:annotatedTarget "Animals respond to anoxic (trace oxygen levels) stress after a shorter exposure time compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001381 ;
    owl:annotatedTarget "Animals fail to respond to trace amounts of oxygen that elicit a response in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000111 ;
    owl:annotatedTarget "Any variation in the cellular or subcellular distribution of a gene product compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0006464", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001382 ;
    owl:annotatedTarget "Variations in the covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications), compared to control. This includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000112 ;
    owl:annotatedTarget "Variations in the biogenesis and stability of protein molecules compared to control." .

[]
    oboInOwl:hasDbXref "GO:0006479", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001383 ;
    owl:annotatedTarget "Variations in the processes that incorporate methyl groups to one or more amino acids within a protein, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000113 ;
    owl:annotatedTarget "Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control." .

[]
    oboInOwl:hasDbXref "GO:0000003", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001384 ;
    owl:annotatedTarget "Animals exhibit a reduction in the production of new individuals that contain some portion of their genetic material inherited from that organism as a result of defective gametes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001475", "WB:WBPaper00028819", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001385 ;
    owl:annotatedTarget "Relatively unspecialized germ cells prematurely acquire the specialized properties of mature oocytes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001386 ;
    owl:annotatedTarget "Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) in adult hermaphrodites during sexual reproduction." .

[]
    oboInOwl:hasDbXref "GO:0050684", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000114 ;
    owl:annotatedTarget "Variations in the biogenesis and stability of messenger RNA molecules compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033007", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001387 ;
    owl:annotatedTarget "Failure of male-derived sperm to fuse with an oocyte during sexual reproduction." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001388 ;
    owl:annotatedTarget "Organisms respond to a lower dosage of gamma rays or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001389 ;
    owl:annotatedTarget "Cells fail to respond to the dosage of gamma irradiation that elicits a response in control animals. Alternatively, cells require longer exposure times to gamma irradiation to mimic the response observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001390 ;
    owl:annotatedTarget "Cells respond to a lower dosage of UV or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001391 ;
    owl:annotatedTarget "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000115 ;
    owl:annotatedTarget "Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb)." .

[]
    oboInOwl:hasDbXref "GO:0051726", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001392 ;
    owl:annotatedTarget "Cells of the animals cease during one of its replicative phases (G1, S, G2, M)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000116 ;
    owl:annotatedTarget "Animals die in between the early and late larval stages. In C. elegans, this occurs during the L2- L3 larval stages of the life cycle." .

[]
    oboInOwl:hasDbXref "GO:0045851", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001393 ;
    owl:annotatedTarget "Variations in the processes that reduce the internal pH of a cell (measured by the concentration of the hydrogen ion), compared to control." .

[]
    oboInOwl:hasDbXref "GO:0045851", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001394 ;
    owl:annotatedTarget "Animals lack the capacity to reduce the internal pH of a cell." .

[]
    oboInOwl:hasDbXref "GO:0005776", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001395 ;
    owl:annotatedTarget "Vacuoles accumulate in the body. A vacuole is a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001894", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001396 ;
    owl:annotatedTarget "Animals completely lack any pharyngeal pumping motion." .

[]
    oboInOwl:hasDbXref "GO:0070265", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001397 ;
    owl:annotatedTarget "Animals exhibit an increase in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0043005", "WB:WBPaper00028886", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001398 ;
    owl:annotatedTarget "Animals display variations in the structure, organization of components, or spatial pattern of any projection stemming from a neuronal cell, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0005886", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001399 ;
    owl:annotatedTarget "Any variation in the structure, form or composition of the semipermeable lipid bilayer that creates a boundary between the interior and exterior environment for cells, cellular organelles and tissues, within an organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001400 ;
    owl:annotatedTarget "Animals exhibit variations in the measured expression of a protein compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001401 ;
    owl:annotatedTarget "The morphological appearance of mitochondria is varied compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0007006", "WB:WBPaper00032231", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001402 ;
    owl:annotatedTarget "Mitochondria are interconnected by thin tubules of mitochondrial inner or outer membrane." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001403 ;
    owl:annotatedTarget "Any variation in the placement of a protein, as detected by antibody staining, within in a cell or cellular compartment compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001404 ;
    owl:annotatedTarget "Any variation that results in the detection of protein expression in cells/tissues through antibody staining, that is otherwise not observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00034765", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001405 ;
    owl:annotatedTarget "Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001406 ;
    owl:annotatedTarget "Variations that result in a decrease in protein expression in male animals compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001407 ;
    owl:annotatedTarget "Variations that result in a decrease in protein expression in specific cells compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001408 ;
    owl:annotatedTarget "Any variation in the cellular or subcellular distribution of a protein compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001409 ;
    owl:annotatedTarget "Any variation that results in the cellular expression of a protein in cells/tissues, that is otherwise not observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001410 ;
    owl:annotatedTarget "Animals fail to express a given protein or class of proteins." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001576", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001411 ;
    owl:annotatedTarget "Animals exhibit an altered display of glycosylated proteins or lipids or altered access to glycosylated moieties along their surface from that observed in control animals of the same developmental stage. In C. elegans, variations in surface accessible glycosylated species are often revealed by altered lectin-binding from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000465", "WB:WBPaper00031415", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001412 ;
    owl:annotatedTarget "Animals exhibit variations in the organization of the longitudinal ridges on the cuticle along the length of the animal, from that observed for control animals of the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026735", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001413 ;
    owl:annotatedTarget "Animals do not exhibit tail-swelling in response to infection by a bacterial pathogen (such as Microbacterium nematophilum) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000117 ;
    owl:annotatedTarget "Animals die at the L1 stage of the life cycle." .

[]
    oboInOwl:hasDbXref "GO:0060179", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001414 ;
    owl:annotatedTarget "Males exhibit defects in the specific actions or reactions that are associated with reproduction." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026735", "WB:WBPerson2987", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001415 ;
    owl:annotatedTarget "Animals exhibit variations that result in variations in the ability of or extent to which pathogens adhere to the surface of animals, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028877", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001416 ;
    owl:annotatedTarget "Pathogens are unable to adhere/colonize the surface of host animals. This defect is often associated with changes in cuticle surface properties of the host." .

[]
    oboInOwl:hasDbXref "GO:0009819", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001417 ;
    owl:annotatedTarget "Any variation in the state or activity of an organism in response to extreme dryness or drought-like conditions, compared to control ." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001418 ;
    owl:annotatedTarget "Animals respond to less severe drought-like conditions or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001419 ;
    owl:annotatedTarget "Animals respond to emetine at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005238", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001420 ;
    owl:annotatedTarget "Animals can move thorough a lawn of bacterially produced biofilm without accumulating an enormous amount of biofilm on its nose. When C. elegans is exposed to certain bacteria (e.g., Y. pestis), a biofilm accumulates on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth." .

[]
    oboInOwl:hasDbXref "GO:0016197", "WB:WBPaper00031894", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001421 ;
    owl:annotatedTarget "Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control." .

[]
    oboInOwl:hasDbXref "GO:0016197", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001422 ;
    owl:annotatedTarget "Animals exhibit defects in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001423 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the coelomocyte to carry out its normal functions or activities, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0009987", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001424 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the oocyte to carry out its normal functions or activities, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0006898", "WB:WBPerson2021", "WB:cab", "pmid:16042554" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001425 ;
    owl:annotatedTarget "Animals exhibit defects in the cell-mediated uptake of external materials via receptor activity. Receptor-mediated endocytosis ensures specificity of transport and generally occurs via clathrin-coated pits and vesicles. In C. elegans, this is often judged by the lack of yolk uptake in oocytes." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:16042554" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001426 ;
    owl:annotatedTarget "Fluid-phase endocytosis by coelomocytes is less frequent or efficient compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001427 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004718", "WB:WBPaper00031894", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001428 ;
    owl:annotatedTarget "Vacuoles accumulate in the intestine." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:17203072" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001429 ;
    owl:annotatedTarget "Animals accumulate an excess of vesicle-like structures in cells." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000118 ;
    owl:annotatedTarget "L2 lethal: Animals die at the L2 stage of the life cycle." .

[]
    oboInOwl:hasDbXref "GO:0007040", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001430 ;
    owl:annotatedTarget "Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001431 ;
    owl:annotatedTarget "Male tails fail to undergo tip retraction thereby forming a 'leptoderan' or 'pointed' adult tail." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000119 ;
    owl:annotatedTarget "Any change that results in higher than normal levels of protein expression compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:16806150" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001432 ;
    owl:annotatedTarget "Adult males exhibit a truncated tail, often without a fan or have well-developed fans but squarish, truncated back ends compared to control. In C. elegans this is due to precocious male tail tip retraction beginning in the early L3 stage (normally retraction begins in the L4 stage). Condition can be lethal if the function of the anus is affected." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001433 ;
    owl:annotatedTarget "Two or more individual cells form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes at an earlier stage of development compared to comparable cells in control animals." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000120 ;
    owl:annotatedTarget "Any change that results in lower than normal levels of protein expression compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0006935", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001434 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific chemical concentration gradient compared to control. Directed movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002087", "WB:WBPaper00004609", "WB:WBPaper00026812" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001435 ;
    owl:annotatedTarget "Failure in directed movement in response to ammonium chloride compared to control. In C. elegans, NH4Cl is an attractant. NH4Cl has also subsequently been used to assay for Cl- attraction in C. elegans." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0001435 ;
    owl:annotatedTarget "chloride chemotaxis defective" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028963", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001436 ;
    owl:annotatedTarget "Animals tend to initiate a response more often, compared to control, after nose-on collisions with an object. In C. elegans, animals initiate backwards movement in response to nose touch." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028963" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001437 ;
    owl:annotatedTarget "Animals execute a response, via directed movement to octanol at a lower concentration or shorter exposure time compared to control. In C. elegans, animals avoid octanol." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001438 ;
    owl:annotatedTarget "Animals fail to move towards attractive volatile organic molecules. In C. elegans, these compounds are sensed by the AWA and AWC neurons." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002033", "WB:WBPaper00028386" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001439 ;
    owl:annotatedTarget "Animals fail to move towards attractive anions." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004609" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001440 ;
    owl:annotatedTarget "Animals fail to move towards attractive cations." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001441 ;
    owl:annotatedTarget "Animals fail to move towards attractive water-soluble chemicals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000650", "WB:WBPaper00004609", "WB:WBPaper00006394" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001442 ;
    owl:annotatedTarget "Failure in directed movement in response to sodium acetate. In C. elegans, sodium acetate is an attractant. Sodium acetate has also subsequently been used to assay for Na+ attraction in C. elegans." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0001442 ;
    owl:annotatedTarget "sodium chemotaxis defective" .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001443 ;
    owl:annotatedTarget "Animals exhibit variations in response to water-soluble chemicals, compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5150" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001444 ;
    owl:annotatedTarget "Animals do not exhibit characteristic desensitization to a water-soluble chemo-attractive signal in a time-concentration dependent and reversible manner compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5150" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001445 ;
    owl:annotatedTarget "Animals do not exhibit characteristic chemoattractive desensitization to sodium acetate in a time-concentration dependent and reversible manner compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5150" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001446 ;
    owl:annotatedTarget "Animals do not exhibit characteristic chemoattractive desensitization to sodium chloride in a time-concentration dependent and reversible manner compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc5150" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001447 ;
    owl:annotatedTarget "Animals do not exhibit characteristic chemoattractive desensitization to ammonium chloride in a time-concentration dependent and reversible manner compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001448 ;
    owl:annotatedTarget "Animals fail to move away from repellant volatile organic chemicals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001449 ;
    owl:annotatedTarget "Animals fail to move away from repellent water soluble chemicals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006481" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001450 ;
    owl:annotatedTarget "Animals exhibit variations through directed movement, in response to repellant water soluble chemicals, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002135", "WB:WBPaper00006481", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001451 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of garlic compared to control. In C. elegans, garlic is typically a repellant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001452 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of octanol. In C. elegans, octanol is typically a repellant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001453 ;
    owl:annotatedTarget "Animals exhibit variations in their avoidance response to high concentrations of sodium chloride solution compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002135", "WB:WBPaper00027118", "WB:WBPaper00035961", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001454 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of the bitter tastant quinine, a water soluble molecule. In C. elegans, quinine is typically a repellant." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001786" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001455 ;
    owl:annotatedTarget "Animals exhibit variations through directed movement, in response to repellant volatile organic chemicals, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001456 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of nonanone. In C. elegans, nonanone is typically a repellant." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001457 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of bromide. In C. elegans, bromide is typically an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001458 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of chloride." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0001458 ;
    owl:annotatedTarget "ammonium chloride chemotaxis abnormal" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001459 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of iodide." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387", "WB:WBPaper00004609", "WB:WBPaper00026812" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001460 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of ammonium chloride. In C. elegans, at specific concentrations, ammonium chloride is an attractant. NH4Cl has also been used to assay for Cl- attraction." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0001460 ;
    owl:annotatedTarget "chloride chemotaxis abnormal" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387", "WB:WBPaper00000650", "WB:WBPaper00004609)" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001461 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium acetate. In C. elegans, at specific concentrations, sodium acetate is an attractant. Sodium acetate has also been used to assay for Na+ attraction." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0001461 ;
    owl:annotatedTarget "sodium chemotaxis abnormal" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001462 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium chloride. In C. elegans, at specific concentrations, sodium chloride is an attractant." .

[]
    oboInOwl:hasDbXref "GO:0043327", "WB:WBPaper00000387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001463 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of cAMP." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000387" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001464 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of cGMP." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001465 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of acetone. In C. elegans, at specific concentrations, acetone is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001466 ;
    owl:annotatedTarget "Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWA sensory neuron in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001467 ;
    owl:annotatedTarget "Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWC sensory neuron in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001468 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of benzaldehyde. In C. elegans, at specific concentrations, benzaldehyde is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001469 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of butanone. In C. elegans, at specific concentrations, butanone is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001470 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of diacetyl. In C. elegans, at specific concentrations, diacetyl is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001471 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of hexanol. In C. elegans, at specific concentrations, hexanol is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001472 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of isoamyl alcohol. In C. elegans, at specific concentrations, isoamyl alcohol is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001473 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanol. In C. elegans, at specific concentrations, pentanol is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001474 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of pyrazine. In C. elegans, at specific concentrations, pyrazine is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001475 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of trimethylthiazole. In C. elegans, at specific concentrations, trimethylthiazole is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001937", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001476 ;
    owl:annotatedTarget "Any variation in the defecation motor program that involves the contraction of the anterior body wall muscles compared to control." .

[]
    oboInOwl:hasDbXref "GO:0008089", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001477 ;
    owl:annotatedTarget "Any variation in the directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001478 ;
    owl:annotatedTarget "Any variation in the elongation of embryonic epidermal cells compared to control. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." .

[]
    oboInOwl:hasDbXref "GO:0043695", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001479 ;
    owl:annotatedTarget "Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that induces dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001480 ;
    owl:annotatedTarget "Variations in the rhythmic relaxations of the a highly specialized cuticle region of the pharynx inside the lumen of the second bulb, compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001481 ;
    owl:annotatedTarget "The number of body thrashes within an aqueous environment in a given period of time is increased, compared with control worms." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024949", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001482 ;
    owl:annotatedTarget "Animals exhibit a reduction in the frequency of oscillations between adjacent body segments from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004310", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001483 ;
    owl:annotatedTarget "The eggs being deposited by adults are of a later developmental stage, compared to control. In C. elegans, this is likely to be a consequence of delayed active egg-laying periods." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004136" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001484 ;
    owl:annotatedTarget "Animals fail to execute directed movement in response to ammonium acetate. In C. elegans, ammonium acetate is an attractant." .

[]
    oboInOwl:hasDbXref "GO:0006412", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000121 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways resulting in the formation of a protein, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0030968" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001485 ;
    owl:annotatedTarget "Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001486 ;
    owl:annotatedTarget "Animals accumulate unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria." .

[]
    oboInOwl:hasDbXref "GO:0016485", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000122 ;
    owl:annotatedTarget "Any variation in the posttranslational modification of a protein (which may include cleavage of peptide bonds) leading to the attainment of the full functional capacity of the protein compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000123 ;
    owl:annotatedTarget "Variations that cause a decrease in the expression level of a biological catalyst, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson363", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001487 ;
    owl:annotatedTarget "Animals exhibit variations in the development of the male elongated sclerotized structures covered by a hardened layer of cuticle in the tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control." .

[]
    oboInOwl:hasDbXref "WB:kmva" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000013 ;
    owl:annotatedTarget "Failure to form dauer larvae under dauer-inducing conditions." .

[]
    oboInOwl:hasDbXref "WB:WBPerson363", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001488 ;
    owl:annotatedTarget "Animals exhibit variations in the development of the sclerotic cuticle that forms the roof of the proctodeum (gubernaculum) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027278", "WB:WBPerson363", "WB:WBPerson712", "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001489 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or composition of the sclerotic cuticle that forms the roof of the proctodeum, from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc4499" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001492 ;
    owl:annotatedTarget "Animals lack a properly developed posterior region compared to control. In C. elegans, mutants exhibit a severely deformed posterior region with a variable knob-like shape; accompanied by arrest at about the time of hatching with fairly normal pharyngeal and anterior development. Most mutants arrest as L1 larvae, and 5% do not hatch." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:16300753" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001493 ;
    owl:annotatedTarget "VPCs (vulval precursor cells) divide at an earlier stage of development compared to control animals; in C. elegans, VPCs divide in the mid-L3 stage to generate the 22 cells that comprise the vulva." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:16300753" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001494 ;
    owl:annotatedTarget "DTCs migrate at an earlier stage of development, compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001495 ;
    owl:annotatedTarget "Cells divide at an earlier stage of development compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0007091", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001496 ;
    owl:annotatedTarget "Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle." .

[]
    oboInOwl:hasDbXref "GO:0007091", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001497 ;
    owl:annotatedTarget "Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids separate and migrate towards the poles of the spindle." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001498 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the pseudopod of the sperm to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0045132", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001499 ;
    owl:annotatedTarget "Variations in the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle, compared to control." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc2931" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001500 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanedione." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000124 ;
    owl:annotatedTarget "Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001501 ;
    owl:annotatedTarget "Animals fail to discriminate between distinct odorants." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001502 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of a specific chemical that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005064", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001503 ;
    owl:annotatedTarget "Any variation in the mechanisms used to ensure that axons in the ventral nerve cord maintain their correct positioning after termination of axonal outgrowth and target recognition compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001477" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001504 ;
    owl:annotatedTarget "Sterility caused by aberrant maternal components required for normal postembryonic development and/or function of the germ line." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001311", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001505 ;
    owl:annotatedTarget "Any variation in the processes that govern spontaneous backward locomotion compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001311", "WB:WBPaper00026650", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001506 ;
    owl:annotatedTarget "Any variation in the processes that govern the rate at which spontaneous backward locomotion is initiated compared to control." .

[]
    oboInOwl:hasDbXref "GO:0009410", "WB:WBPaper00004264", "WB:WBPaper00004776", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001507 ;
    owl:annotatedTarget "Animals fail to be affected by toxins produced by Bacillus thuringiensis (Bt toxins) in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029363", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001508 ;
    owl:annotatedTarget "Any perturbation that disrupts the fusion between the anchor cell and the surrounding utse syncytium. Such variations result in the loss of uterine-vulval connectivity and continuity." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001509 ;
    owl:annotatedTarget "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are absent." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001510 ;
    owl:annotatedTarget "Any variation in the processes that govern acquisition of neuronal cell fates compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028966", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001511 ;
    owl:annotatedTarget "Variations in the stereotypical migration pattern of the linker cell in a developing male compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037739", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001512 ;
    owl:annotatedTarget "Bilaterally symmetric cell fail to acquire specific left-right asymmetric properties such as L/R specific cell position, cell death or gene expression." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001513 ;
    owl:annotatedTarget "Variations in the process of secretion of a class of membrane-bound vesicles found inside neurons, gland cells, and some epithelial cells in which the central core appears darkly stained when viewed in thin section by electron microscopy, compared to control. Exocytosis occurs via the fusion of the vesicle with the plasma membrane of a cell (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001499", "WB:WBPaper00029065", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000014 ;
    owl:annotatedTarget "Variations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001514 ;
    owl:annotatedTarget "Variations in the uptake of a small membrane-bound organelle, filled with neurotransmitter(s) and/or neuropeptides, by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle compared to control(Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000465", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001515 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity or patterning of electron-dense columnar structures that join the basal and cortical cuticle layers, from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000465", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001516 ;
    owl:annotatedTarget "Animals exhibit a helically twisted cuticle. In practice the degree of twisting is measured as the number of helical twists the alae make about anterior/posterior axis of the animal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000465", "WB:WBPaper00031415", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001517 ;
    owl:annotatedTarget "Animals exhibit variations in the circumferential pattern of ridges in the outer cortical layer of the cuticle, compared to that observed in control animals of the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000365" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001518 ;
    owl:annotatedTarget "Any variation in the levels and/or localization of biogenic amines compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001519 ;
    owl:annotatedTarget "Any variation in the orderly movement of cells along the posterior axis of the animal (abolished, misdirected or incomplete) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001520 ;
    owl:annotatedTarget "Any variation in the orderly movement of neurons along the posterior axis of the animal(abolished, misdirected or incomplete) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001521 ;
    owl:annotatedTarget "Embryos retract after the embryonic elongation process." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001522 ;
    owl:annotatedTarget "The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) constitutively extend into the external environment through the cloacal opening. In C. elegans males there are two copulatory spicules." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000125 ;
    owl:annotatedTarget "Any variation that results in an increase in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001523 ;
    owl:annotatedTarget "Any variation in the makeup, density or area of the ECM compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001524 ;
    owl:annotatedTarget "Exhibition of quiescent behavior under inappropriate conditions and improper recovery from quiescent state. Quiescent behavior is normally coupled with lethargus." .

[]
    oboInOwl:hasDbXref "WB:cab", "WB:cgc7141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000126 ;
    owl:annotatedTarget "Variations in the time from pronuclei meeting to furrow initiation during the first cell division compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001525 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of the posterior region of the pharynx compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000503", "WB:WBPaper00029016", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001526 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or organization of any one of the specialized sensory receptor cells of the nervous system that compared to control animals. In C. elegans, these specialized cells are characterized as having axoneme containing dendritic projections emanating from their cell body." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001527 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head or along the tail, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000932", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001528 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of any component of the sensillum channel including the sheath and or socket cells, their junctions with each other, channel neurons or surrounding epithelia compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001529 ;
    owl:annotatedTarget "OBSOLETE: Any variation in the form, structure or composition of an interfacial epithelial cell which forms a specialized environment surrounding the ciliated sensory ending(s) of one or more neurons and is often accompanied by a more distal socket cell compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000214", "WB:WBPaper00000503", "WB:WBPaper00000932", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001530 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000214", "WB:WBPaper00000938", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001531 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001532 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001533 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000502", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001534 ;
    owl:annotatedTarget "Any variation in makeup, density or area of the ECM lending structure to neurons compared to control animals. In C. elegans, the neuronal ECM is sometimes referred to as a mantle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000938", "WB:WBPaper00029016", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001535 ;
    owl:annotatedTarget "Animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001536 ;
    owl:annotatedTarget "Embryos exhibit variations in the patterning of differentiated cell types, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004926" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001537 ;
    owl:annotatedTarget "Any variation in the ability of cells to monitor the quality of their mRNAs and degrade any transcripts that are poorly or incompletely translated compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001192", "WB:WBPaper00004926" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001538 ;
    owl:annotatedTarget "Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001539 ;
    owl:annotatedTarget "Animals exhibit variations in the entry into the dauer stage when exposed to conditions that induce dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000127 ;
    owl:annotatedTarget "Characteristic exit from the dauer stage is altered compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001540 ;
    owl:annotatedTarget "The life span of dauer-staged animals is either longer or shorter than that observed in control dauer animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001541 ;
    owl:annotatedTarget "Variations in the execution of the developmentally-regulated cell cycle arrest in the gonad during the dauer stage, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001542 ;
    owl:annotatedTarget "Any variation in the inhibition of feeding which is induced/occurs during the dauer stage compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001543 ;
    owl:annotatedTarget "Dauer stage animals exhibit a decrease in self-propelled movement on a solid medium compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cgc424" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000128 ;
    owl:annotatedTarget "Animals are more likely to form dauers at temperatures that do not induce dauer entry in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001544 ;
    owl:annotatedTarget "Variations in the state or activity of a dauer stage organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000129 ;
    owl:annotatedTarget "Animals do not enter dauer at a temperature that induces dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001545 ;
    owl:annotatedTarget "Any variation in the overall structure or appearance of an animal progressing through an alternative larval stage in response to environmental stresses compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001546 ;
    owl:annotatedTarget "Variations which lead to the decreased ability of dauer larva to survive at extreme conditions, such as high or low temperatures, the presence of dilute acids, detergents, anesthetics, or even fixatives, compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001547 ;
    owl:annotatedTarget "Animals exhibit variations in the chemical reactions and pathways that occur during the dauer life stage, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001548 ;
    owl:annotatedTarget "Any variation in the ratio of the body length to body width in a dauer stage animal, compared to control. Long thin animals will have a high axial ratio." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001549 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000130 ;
    owl:annotatedTarget "Animals enter the dauer stage when exposed to lower concentrations or shorter exposure times of chemicals that induce dauer formation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001550 ;
    owl:annotatedTarget "Variations in the form or composition of the cuticle-lined lumenal region which lies just behind the lips at the entrance to the pharyngeal lumen in dauer stage animals compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000131 ;
    owl:annotatedTarget "Animals do not enter dauer when exposed to chemicals that induce dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001551 ;
    owl:annotatedTarget "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) during the dauer larva stage, compared to control animals (Wormatlas). The dauer larval stage is a developmentally arrested larval stage that is specialized for survival under harsh, or otherwise unfavorable environmental conditions." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000132 ;
    owl:annotatedTarget "Animals exhibit variations in the entry into the dauer stage when exposed to concentrations of chemicals that induce dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001552 ;
    owl:annotatedTarget "Variations in the form or composition of the mouthparts at the anterior end of the digestive tract during the dauer stage, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000133 ;
    owl:annotatedTarget "The levels of an enzyme involved in the manufacture of lipids are decreased compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001553 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001554 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001555 ;
    owl:annotatedTarget "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the dauer sensory system, compared to control. The dauer sensory system is used to perceive the physical and chemical environment during the dauer larval stage." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000134 ;
    owl:annotatedTarget "Animals exhibit a decrease in the intensity of expression of a gene product compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001556 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000135 ;
    owl:annotatedTarget "Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001557 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001558 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001559 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001560 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001561 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001562 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001563 ;
    owl:annotatedTarget "Dauer stage animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002419", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001564 ;
    owl:annotatedTarget "The window of production of self-fertilized eggs exceeds or does not extend to the same length as control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001481", "WB:WBPaper00001786", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001565 ;
    owl:annotatedTarget "Failure to execute characteristic response to lysine as defined by control animals. In C. elegans, lysine is an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027244", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001566 ;
    owl:annotatedTarget "Any variation in the process that regulates the migration of ventral epidermal cells toward the ventral midline (to encase underlying cells in an epithelial monolayer) in developing embryos compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001567 ;
    owl:annotatedTarget "Nuclei of specific cells are larger compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033456", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000136 ;
    owl:annotatedTarget "Animals exhibit elevated levels of messenger RNA compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005960" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001568 ;
    owl:annotatedTarget "Any variation in the export of mRNA from the cell nucleus compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001894", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001569 ;
    owl:annotatedTarget "The characteristic organization of myosin filaments into discrete A-bands within the muscle cells is disrupted. In C. elegans, myosin filaments no longer appear as continuous longitudinally oriented fibers across the muscle quadrants." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0001569 ;
    owl:annotatedTarget "body wall muscle thick myofilament organization abnormal" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001894", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001570 ;
    owl:annotatedTarget "The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0001570 ;
    owl:annotatedTarget "body wall muscle thin myofilament organization abnormal" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001895" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001571 ;
    owl:annotatedTarget "Variations in the accumulation of muscle proteins at membranes where adjacent muscle cells contact each other and the hypodermis compared to control. In C. elegans, during early embryonic body wall muscle development, muscle, basement membrane, and hypodermal components are all colocalized in a continuous linear structure at the site of muscle-hypodermal contact." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000178", "WB:WBPaper00001206", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001572 ;
    owl:annotatedTarget "Animals that are not ordinarily male, exhibit male-specific attributes. In C. elegans, XX animals exhibit male-specific attributes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001573 ;
    owl:annotatedTarget "Animals exhibit variations in the response to the addition of nicotine compared to that observed in control animals. Nicotine is a cholinergic agonist." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001574 ;
    owl:annotatedTarget "Animals exhibit variations in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001575 ;
    owl:annotatedTarget "Animals exhibit a decrease in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." .

[]
    oboInOwl:hasDbXref "GO:0048311", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001576 ;
    owl:annotatedTarget "Variations in the spatial distribution of the mitochondria within the cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028954" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001577 ;
    owl:annotatedTarget "Animals exhibit variations in the parallel arrangement of mitochondria within a cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001578 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of cholinergic agonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001579 ;
    owl:annotatedTarget "Animals respond to a cholinergic agonist at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0051081", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001580 ;
    owl:annotatedTarget "Any variation in the progression of the controlled breakdown of the nuclear envelope, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001011", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001581 ;
    owl:annotatedTarget "Levels of transcripts associated with genes on the X chromosome are increased compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001011", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001582 ;
    owl:annotatedTarget "Levels of transcripts associated with genes on the X chromosome are decreased compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001583 ;
    owl:annotatedTarget "Animals segregate progeny with 3 X chromosomes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033456", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000137 ;
    owl:annotatedTarget "Animals exhibit decreased levels of messenger RNA compared to control." .

[]
    oboInOwl:hasDbXref "GO:0051310", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001584 ;
    owl:annotatedTarget "Any variation in the movement of chromosomes to the spindle equator during mitosis compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000138 ;
    owl:annotatedTarget "The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals." .

[]
    oboInOwl:hasDbXref "GO:0008356", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001585 ;
    owl:annotatedTarget "Any variation in a cell's ability to divide asymmetrically to produce two daughter cells with different developmental potentials compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001423", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001586 ;
    owl:annotatedTarget "Animals contain more than one anchor cell. In C. elegans, presumptive ventral uterine cells undergo fate transformation and instead acquire the properties of an anchor cell (often due to defects in lateral signaling)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000139 ;
    owl:annotatedTarget "Animals exhibit variations in survival when exposed to stress stimuli that induce lethality in control animals." .

[]
    oboInOwl:hasDbXref "GO:0030036", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001587 ;
    owl:annotatedTarget "Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000140 ;
    owl:annotatedTarget "Animals exhibit variations in cessation of development when exposed to stress stimuli that induce developmental arrest in control animals." .

[]
    oboInOwl:hasDbXref "GO:0000226", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001588 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000141 ;
    owl:annotatedTarget "Animal populations exhibit a further decrease in survival when exposed to stress stimuli compared to the lethality rate observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0007020" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001589 ;
    owl:annotatedTarget "Any variation that alters the characteristic de novo formation of a microtubule compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007019" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001590 ;
    owl:annotatedTarget "Any variation that alters the characteristic removal of tubulin heterodimers from one or both ends of a microtubule compared to control." .

[]
    oboInOwl:hasDbXref "GO:0046785" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001591 ;
    owl:annotatedTarget "Any variation that alters the characteristic addition of tubulin heterodimers to one or both ends of a microtubule compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031286" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001592 ;
    owl:annotatedTarget "Alternating periods of stopping and moving; Motion is interrupted by periods of inactivity lasting several seconds." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005399", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001593 ;
    owl:annotatedTarget "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control. In C. elegans this silencing occurs only in the germline." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001594 ;
    owl:annotatedTarget "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the germline, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001595 ;
    owl:annotatedTarget "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the soma, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024194", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001596 ;
    owl:annotatedTarget "Swelling of the tail hypodermis resulting in a prematurely-truncated and thickened appearance of the tail. In C. elegans, this is usually applies to hermaphrodites." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001423", "WB:WBPaper00002946", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001597 ;
    owl:annotatedTarget "Any variation that results in a fewer than control number of muscle cells." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001598 ;
    owl:annotatedTarget "Treatment with inhibitors of serotonin reuptake does not elicit the same response as observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000484", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001599 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of ouabain that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, resistance to ouabain is often assayed via body contraction response." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000484" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001600 ;
    owl:annotatedTarget "Animals require increased concentration or longer exposure to ouabain to elicit the rapid muscular contractions seen in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001601 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of biogenic amine receptor antagonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031241", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001602 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of methiothepin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031241", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001603 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of cyproheptadine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031241", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001604 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of mianserin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031241", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001605 ;
    owl:annotatedTarget "Animals do not live longer in response to mianserin compared to control." .

[]
    oboInOwl:hasDbXref "GO:0033554", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000142 ;
    owl:annotatedTarget "Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002358", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001606 ;
    owl:annotatedTarget "Animals respond to ethanol at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002358", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001607 ;
    owl:annotatedTarget "Animals become paralyzed in response to ethanol at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002037", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001608 ;
    owl:annotatedTarget "Animals respond to the anesthetic enflurane at lower concentrations or shorter exposure times than control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002037", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001609 ;
    owl:annotatedTarget "Animals respond to the anesthetic isoflurane at lower concentrations or shorter response times than control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001063", "WB:WBPaper00002037", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001610 ;
    owl:annotatedTarget "Animals respond to the anesthetic ether at lower concentrations or shorter response times than control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000958", "WB:WBPaper00031286", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001611 ;
    owl:annotatedTarget "Animals respond to the lipid-soluble anesthetic halothane at lower concentrations or shorter response times compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002358", "WB:WBPaper00031371", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001612 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of ethanol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to ethanol to elicit the response compared to control animals. In C.elegans the phenotype designation Jud is short for JUDang, which is Korean for resistant to alcohol." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031371", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001613 ;
    owl:annotatedTarget "Animals in the presence of ethanol continue to respond to touch under conditions when control worms have stopped responding to stimuli." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001614 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a specific anticonvulsant compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024698", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001615 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of compounds that act as anticonvulsants that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024698", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001616 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of trimethadione, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000143 ;
    owl:annotatedTarget "Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001617 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of ethosuximide, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000144 ;
    owl:annotatedTarget "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004721", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001618 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of the anesthetic halothane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000015 ;
    owl:annotatedTarget "Variations in the movement towards typically attractive chemicals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004721", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001619 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of the volatile anesthetic isoflurane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001620 ;
    owl:annotatedTarget "Animals exhibit variations in their response to oxidative stress compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001621 ;
    owl:annotatedTarget "Animals respond to a lower concentration of reactive oxygen species or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002487", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001622 ;
    owl:annotatedTarget "Animals lay eggs at a greater rate in response to exogenous serotonin compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001861", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001623 ;
    owl:annotatedTarget "Any variation in the posture of the male tail after application of exogenous serotonin compared to control. In C. elegans, males respond with a tight ventral curling of the male tail in response to serotonin." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001861", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001624 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of serotonin that elicits a male tail curling response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001861", "WB:WBPaper00028762", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001625 ;
    owl:annotatedTarget "Males respond to serotonin by curling their tails at a lower concentration or a shorter exposure compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001626 ;
    owl:annotatedTarget "Any variation in the locomotion rate after application of exogenous serotonin compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001627 ;
    owl:annotatedTarget "The decrease in locomotion rate in the presence of serotonin is greater than control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002141" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001628 ;
    owl:annotatedTarget "Animals fail to decrease their locomotion rate in response the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000635", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001629 ;
    owl:annotatedTarget "Any variation in egg laying behavior after application of exogenous serotonin compared to control. In C. elegans, serotonin induces egg laying." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001630 ;
    owl:annotatedTarget "Any variation in the developmental progression of the intestine that leads to a blockage in the alimentary canal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001631 ;
    owl:annotatedTarget "Animals produce ova/sperm that contain no X chromosome in a nonmendelian segregation pattern." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001632 ;
    owl:annotatedTarget "Animals produce ova/sperm that contain 2 X chromosomes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001633 ;
    owl:annotatedTarget "Animals produce ova/sperm that contain lethal factors as a result of chromosomal disjunction defects." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001634 ;
    owl:annotatedTarget "Animals respond to compounds that elicit electrophilic stress at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0000003", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000145 ;
    owl:annotatedTarget "Animals exhibit variations in the time of onset or duration of the fertile period, or production of new individuals that contain some portion of their genetic material inherited from that organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001584", "WB:WBPaper00002922", "WB:WBperson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001635 ;
    owl:annotatedTarget "Animals contain an excess number of pharyngeal cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001584", "WB:WBPaper00002330", "WB:WBperson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001636 ;
    owl:annotatedTarget "Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002946", "WB:WBperson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001637 ;
    owl:annotatedTarget "Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells." .

[]
    oboInOwl:hasDbXref "GO:0034058", "WB:WBPaper00029049", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001638 ;
    owl:annotatedTarget "OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003743", "WB:WBPaper00031455", "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001639 ;
    owl:annotatedTarget "Animals exhibit a decrease in their high-speed movement in the forward direction with brief backward movement compared to control. In C. elegans, Animals do not move more than a few body lengths from their starting position and searches occur locally with pivoting behavior." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031246", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001640 ;
    owl:annotatedTarget "Animals are unable to acidify compartments to the same level as that observed in control animals given the same stimulus." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031426", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001641 ;
    owl:annotatedTarget "Animals lack or exhibit defects in the posterior body muscle contractions during the defecation cycle." .

[]
    oboInOwl:hasDbXref "GO:0040016", "WB:WBPaper00001032", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001642 ;
    owl:annotatedTarget "Variations that disrupt stereotypical embryonic cleavage patterns (such as cleavage rate, division axes or asymmetric division)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001643 ;
    owl:annotatedTarget "Embryos generate an excess number of hypodermal cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001644 ;
    owl:annotatedTarget "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of proteins in the organism compared to control." .

[]
    oboInOwl:hasDbXref "GO:0030163", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001645 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001521", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001646 ;
    owl:annotatedTarget "Embryos fail to generate cells that exhibit pharyngeal specification." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001647 ;
    owl:annotatedTarget "Any variation in the progression of the posterior portion of the pharynx over time compared to control. In C. elegans the posterior region includes the isthmus and terminal bulb (second bulb)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002330", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001648 ;
    owl:annotatedTarget "Embryos fail to generate cells that give rise to the posterior portion of the pharynx. In C. elegans, the MS blastomere- derived pharyngeal cells constitute the posterior portion of the pharynx." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031571", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001649 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031571", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001650 ;
    owl:annotatedTarget "Germ cell death fails in response to the concentration of 5-FU that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, in addition to cell death, 5-FU exposed animals exhibit condensed germ cell nuclei or unhealthy nuclei." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031571", "WB:WBPerson721" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001651 ;
    owl:annotatedTarget "Animals grow well during or after exposure to 5-FU under conditions where control animals are growth inhibited." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005989" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001652 ;
    owl:annotatedTarget "Any variation in the process by which the gonad anchor cell makes contact with vulval cells in order to create a uterine-vulval connection. In C. elegans, this includes the loss of the basement membranes between these cells and the crossing of the basolateral portion of the anchor cell through this gap." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001653 ;
    owl:annotatedTarget "Animals exhibit variations in their response to cadmium compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000146 ;
    owl:annotatedTarget "Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins or changes in life span." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001654 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of cadmium that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to cadmium to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001655 ;
    owl:annotatedTarget "Animals respond to cadmium at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001656 ;
    owl:annotatedTarget "Any variation in the progression of the leader cell that guides and shapes the outgrowth of the gonad while crawling along the body wall to force the germline to extend into a long tubular shape over time from its formation to its mature structure compared to control." .

[]
    oboInOwl:hasDbXref "GO:0030054", "WB:WBPaper00031590", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001657 ;
    owl:annotatedTarget "Animals exhibit variations in the specialized region of connection between two cells or between a cell and the extracellular matrix compared to control." .

[]
    oboInOwl:hasDbXref "GO:0005911", "WB:WBPaper00031590", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001658 ;
    owl:annotatedTarget "Animals exhibit variations in the specialized region of connection between two cells compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001659 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the somatic gonad structure that connects the distal gonad arm to the uterus compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00030973", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001660 ;
    owl:annotatedTarget "The two morphologically bilaterally symmetric gustatory neurons ASE left (ASEL) and ASE right (ASER) fail to undergo a left/right asymmetric diversification in cell fate." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003760", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001661 ;
    owl:annotatedTarget "The two morphologically bilaterally symmetric olfactory neurons AWC left (AWCL) and AWC right (AWCR) fail to undergo a left/right asymmetric diversification in cell fate." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001662 ;
    owl:annotatedTarget "Any variation in the progression of the somatic gonad structure that connects the distal gonad arm to the uterus over time from an initial condition to a later condition compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001663 ;
    owl:annotatedTarget "Animals fail to respond to the levels of reactive oxygen species that elicit a response in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000179", "WB:WBPaper00000565", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001664 ;
    owl:annotatedTarget "The frequency of sex chromosome segregation is perturbed, resulting in the production of exceptional gametes (e.g. ova or sperm) and populations with a sex ratio altered from the rate of 1:500 as observed for control populations." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000565", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001665 ;
    owl:annotatedTarget "Lower numbers of male progeny occur in the population compared to control populations. In C. elegans, the low incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an decrease in X chromosome nondisjunction." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000565", "WB:WBPaper00003886", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001666 ;
    owl:annotatedTarget "Animals respond to iononizing radiation at a lower dose or a shorter exposure compared to control animals. Iononizing radiation has a wavelength in the 10 to 0.01 nanometer range. In C. elegans, increased sensitivity to X-ray irradiation is often observed as a decrease in survival upon exposure compared to control animals given the same treatment." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000565", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001667 ;
    owl:annotatedTarget "Animals respond to the chemical mutagen methyl methanesulfonate (MMS) a methanesulfonate ester and alkylating agent at a lower concentration or a shorter exposure compared to control animals. In C. elegans, increased sensitivity to MMS can be observed as a decrease in egg hatch upon acute exposure or inhibition of growth after chronic exposure compared to control animals given the same treatment." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006281", "WB:WBPaper00030855" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001668 ;
    owl:annotatedTarget "An increased number of oocytes are retained in the gonad without becoming endomitotic, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0042594", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000147 ;
    owl:annotatedTarget "Any variation in the state or activity of an organism as a result of deprivation of nourishment, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027305", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001669 ;
    owl:annotatedTarget "Animals exhibit a variation in the ratio of synaptic vesicles per synapse of a neuron, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027305", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001670 ;
    owl:annotatedTarget "Animals exhibit an overall decrease in the quantity of synaptic vesicles at the synapse compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000148 ;
    owl:annotatedTarget "Animals exhibit variations in the entry into the dauer stage when exposed to nutrient poor conditions that induce dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001671 ;
    owl:annotatedTarget "Animals display variations in the distribution of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001672 ;
    owl:annotatedTarget "Animals exhibit variations in the extension of the part of the axon that forms a bridge between body regions, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0032204", "WB:WBPaper00031585", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001673 ;
    owl:annotatedTarget "Animals exhibit variations in the processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA, which allow the chromosome to persist from generation to generation, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000149 ;
    owl:annotatedTarget "Animals are more likely to form dauers under nutrient conditions that do not induce dauer entry in control animals." .

[]
    oboInOwl:hasDbXref "GO:0000781", "WB:WBPaper00003886", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001674 ;
    owl:annotatedTarget "Animals exhibit variations in the sequence or organization of the components of the terminal region of its chromosome, (i.e. telomere, which serves to stabilize the chromosome) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000150 ;
    owl:annotatedTarget "Animals do not enter dauer under nutrient-poor conditions that induce dauer formation in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001675 ;
    owl:annotatedTarget "Males exhibit variations in the reproductive system, from its formation to the mature structure compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001930", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000151 ;
    owl:annotatedTarget "Embryos generate an excess number of anterior derived pharyngeal cells. In C. elegans, embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000550", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001676 ;
    owl:annotatedTarget "Animals exhibit variations in the structure or composition of any neuron within the class of sensory neurons responsible for relaying mechanical stimuli to the animal compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002589", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001677 ;
    owl:annotatedTarget "Animals display cuticle components displayed by animals of a different developmental stage, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001576", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001678 ;
    owl:annotatedTarget "Animals produce cuticles that vary in components such as proteins or carbohydrates, observed in control animals of the same developmental stage and raised under the same conditions." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031901", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001679 ;
    owl:annotatedTarget "Neurons have more than one process extending from the cell body." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001680 ;
    owl:annotatedTarget "Vulval precursor cells forgo further cell division and fuse to the hypodermis instead of adopting their intended fate (becoming primary, secondary or tertiary vulval cells)." .

[]
    oboInOwl:hasDbXref "GO:0032154", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000152 ;
    owl:annotatedTarget "One-cell embryos do not form the shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis." .

[]
    oboInOwl:hasDbXref "GO:0051294", "WB:WBPaper00031898", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001681 ;
    owl:annotatedTarget "The alignment of the spindle relative to other cellular structures varies from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001682 ;
    owl:annotatedTarget "Organisms respond to UV at a higer dose or a longer exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002113", "WB:WBPaper00002631" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001683 ;
    owl:annotatedTarget "Variations that specifically disrupt sperm production in XX hermaphrodites. By contrast, spermatogenesis in XO males remains unaffected." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031872", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001684 ;
    owl:annotatedTarget "The rates of synaptic vesicle exocytosis and endocytosis vary from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031872", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001685 ;
    owl:annotatedTarget "The region opposite to the presynaptic region deviates in the structure, configuration or ratio of its components specific for receiving signals from the other side of the synapse compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001686 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process in the region, opposite to the presynaptic region, which is required for receiving signals from the other side of the synapse compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001280", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001687 ;
    owl:annotatedTarget "Cuticles of animals or cuticular extracts exhibit an altered pattern of antibody binding compared to Bristol N2 animals of the same developmental stage." .

[]
    oboInOwl:hasDbXref "GO:0060104" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001688 ;
    owl:annotatedTarget "The electron dense, amorphous envelope that comprises the outermost layer of the cuticle varies in composition from that observed in control animals of the same developmental stage. The integrity of the surface coat is often revealed by an altered antigenicity or biochemical make up." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001280", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001689 ;
    owl:annotatedTarget "Cuticles or cuticular extracts do not bind antibodies that are observed to bind the surfaces or cuticular extracts of Bristol N2 animals of the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002589", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001690 ;
    owl:annotatedTarget "Animals display surface antigens throughout all larval stages, unlike Bristol N2 worms, which display the antigens only during one larval stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031889", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001691 ;
    owl:annotatedTarget "Germ nuclei are misplaced in the gonad and are observed in the rachis. Sheath cells are observed protruding between these nuclei. Meiotic or mitotic specification of germ nuclei is not affected." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002589", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001692 ;
    owl:annotatedTarget "Animals are not induced to display surface antigens by exposure to pheromone as observed for Bristol N2 animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001693 ;
    owl:annotatedTarget "Males have alae that extend into the tail region. Alae are small linear ridges running along the lateral lines of the cuticle. In C. elegans alae do not extend into the tail region (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001883", "WB:WBPaper00002113", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001694 ;
    owl:annotatedTarget "Hermaphrodites continue to produce sperm past the time at which the transition to oogenesis normally occurs. Thus, germ cells that would normally become oocytes are transformed into sperm instead." .

[]
    oboInOwl:hasDbXref "GO:0016757", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001695 ;
    owl:annotatedTarget "Animals exhibit variations in their catalytic ability the transfer glycolsyl groups from one compound (donor) to another (acceptor) often measured by a reduction in the amount of glycosylated products compared to that observed in control animals of the same developmental stage." .

[]
    oboInOwl:hasDbXref "GO:0009058", "WB:WBPaper00029024", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001696 ;
    owl:annotatedTarget "Animals exhibit variations in the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029024", "WB:WBPaper00031153", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001697 ;
    owl:annotatedTarget "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of chondroitin sulfate compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029024", "WB:WBPaper00031153", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001698 ;
    owl:annotatedTarget "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001699 ;
    owl:annotatedTarget "Specific body regions of an animal display variations in movement compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031835", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001700 ;
    owl:annotatedTarget "Animals exhibit variations in movement in liquid from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001701 ;
    owl:annotatedTarget "Animals exhibit uncharacteristic muscle contractions during the process by which they travel from one location to another." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000075", "WB:WBPaper00003740", "WB:WBPaper00031656", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001702 ;
    owl:annotatedTarget "Animals exhibit variations in the directional changes that separate consecutive runs, from that observed for control animals. In C. elegans, these aberrations include variations in the form or extent of omega turns or reversals (shifts from forward to backward movements)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001703 ;
    owl:annotatedTarget "Any variation in the maximum ventral and dorsal flex of the animal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026841", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001704 ;
    owl:annotatedTarget "Alae contain more cuticular ridges than control animals. In C. elegans alae are composed of three cuticular ridges." .

[]
    oboInOwl:hasDbXref "GO:0006913", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001705 ;
    owl:annotatedTarget "The directed movement of molecules between the nucleus and the cytoplasm is impaired." .

[]
    oboInOwl:hasDbXref "GO:0051168", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001706 ;
    owl:annotatedTarget "The directed movement of substances out of the nucleus is impaired." .

[]
    oboInOwl:hasDbXref "GO:0051170", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001707 ;
    owl:annotatedTarget "The directed movement of substances into the nucleus is impaired." .

[]
    oboInOwl:hasDbXref "GO:0006611", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001708 ;
    owl:annotatedTarget "The directed movement of a protein from the nucleus into the cytoplasm is impaired." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032037", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001709 ;
    owl:annotatedTarget "Animals exhibit variations in light/dark cycle recurrence of reactions to stress conditions compared to that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032037", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001710 ;
    owl:annotatedTarget "Animals exhibit variations in light/dark cycle recurrence of reactions to osmotic stress compared to that observed for control animals." .

[]
    oboInOwl:hasDbXref "GO:0007622", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001711 ;
    owl:annotatedTarget "Animals exhibit variations in actions or responses that occur with measurable periodicity, from that observed for control animals." .

[]
    oboInOwl:hasDbXref "GO:0048512", "WB:WBPaper00032037", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001712 ;
    owl:annotatedTarget "Animals exhibit variations in the actions or reactions that recur with a periodicity associated with light/dark cycles, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0045475", "WB:WBPaper00031656", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001713 ;
    owl:annotatedTarget "Animals exhibit variations in locomotor activity during its light/dark cycle from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003740", "WB:WBPaper00026967", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001714 ;
    owl:annotatedTarget "Animals exhibit variations in turning bouts, consisting of one or more sharp turning events separating consecutive runs, which serve to orient the animal within a gradient, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031656", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001715 ;
    owl:annotatedTarget "Animals exhibit variations in the number of directional changes over time from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024949", "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001716 ;
    owl:annotatedTarget "Animals exhibit variations in the velocity of forward translocation of any point along the animal's track from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024949", "WB:WBPaper00031656", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001717 ;
    owl:annotatedTarget "Animals exhibit variations in the translocation of the mean position of the rear two-thirds (centroid position) of the animal over time, from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024949", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001718 ;
    owl:annotatedTarget "Animals exhibit variations in the mean translocation of the points along the animal's track compared to control." .

[]
    oboInOwl:hasDbXref "GO:0030968", "WB:WBPaper00030877", "WB:WBPaper00032003", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001719 ;
    owl:annotatedTarget "Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032030", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001720 ;
    owl:annotatedTarget "Spermatozoa do not crawl back into the spermatheca after being swept into the uterus by passing oocytes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032003", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001721 ;
    owl:annotatedTarget "Animals exhibit variations in the extent of pathogen invasion into the pharynx compared to control. This is often measured as the percentage of animals exhibiting a pathogen-invaded pharynx within a given population." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032003", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001722 ;
    owl:annotatedTarget "Animals exhibit a greater extent of pathogen invasion into the pharynx compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032003", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001723 ;
    owl:annotatedTarget "Animals exhibit a lesser extent of pathogen invasion into the pharynx compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00030877", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001724 ;
    owl:annotatedTarget "Animals respond to tunicamycin at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032031", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001725 ;
    owl:annotatedTarget "Cells exhibit variations in the response to osmotic stress compared to control. In C. elegans, exposure to stress-inducing osmotic conditions invokes cellular changes, including transcriptional up or down-regulation of genes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001726 ;
    owl:annotatedTarget "Animals vary in the distance between anterior and posterior ends of the animal from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001727 ;
    owl:annotatedTarget "Animals vary in the distance between dorsal and ventral sides when measured across the body at right angles to the length, from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032027", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001728 ;
    owl:annotatedTarget "Males differ from control animals in their ability to form copulatory plugs or their placement of these plugs. In C. elegans, males of the Hawaiian strain (CB4856) typically form mating plugs." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002770", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001729 ;
    owl:annotatedTarget "Males form copulatory mating plugs." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002770", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001730 ;
    owl:annotatedTarget "Males do not form copulatory mating plug." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032190", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000153 ;
    owl:annotatedTarget "Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032070", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001731 ;
    owl:annotatedTarget "Animals exhibit variations in the duration of the trajectory of the forward track in a thermal gradient compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032033", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001732 ;
    owl:annotatedTarget "Animals exhibit variations in their response and ability to survive over a range of pH conditions compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001733 ;
    owl:annotatedTarget "Animals treated with pheromone do not exhibit a decrease in pumping rate similar to that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000154 ;
    owl:annotatedTarget "The characteristic number of offspring produced is lower compared to that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001734 ;
    owl:annotatedTarget "Animals deprived of food do not exhibit a decrease in pumping rate similar to that observed for control animals." .

[]
    oboInOwl:hasDbXref "GO:0006937", "WB:WBPaper00032000", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001735 ;
    owl:annotatedTarget "Animals exhibit variations in the frequency, rate or extent of muscle contraction compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031959", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001736 ;
    owl:annotatedTarget "Failure to execute the characteristic response to acetate compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031959", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001737 ;
    owl:annotatedTarget "Animals are unable to locate the gradient peak of a water soluble compound, which was generated on a uniform concentration of another compound." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031959", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001738 ;
    owl:annotatedTarget "Failure to execute the characteristic response to ammonium compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031356", "WB:WBPerson2021", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000155 ;
    owl:annotatedTarget "Contents or structures of the cell are oriented on the opposite side of the cell compared to control animals; In C. elegans, this can result in the fate pattern of descendants being flipped." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032067", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001739 ;
    owl:annotatedTarget "Any variation in an organism's decline over time from its optimal fertility and viability compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000156 ;
    owl:annotatedTarget "Any variation in the time interval between successive contractions of the body wall muscles during the defecation motor program compared to cantrol." .

[]
    oboInOwl:hasDbXref "GO:0010260", "WB:WBPaper00032067", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001740 ;
    owl:annotatedTarget "Any variation in the preprogrammed process that occurs in an organism that is associated with the dismantling of an organ and an overall decline in metabolic function compared to control animals. This may include variations in the rate or extent of morphological disarray and of the breakdown or organelles, membranes and other cellular components." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032000", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001741 ;
    owl:annotatedTarget "Males exhibit spicule-muscle seizures leading to inappropriately timed protraction compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001742 ;
    owl:annotatedTarget "The endogenous anabolism of any lipid species has been increased compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031426", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000157 ;
    owl:annotatedTarget "Animals exhibit variations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0000278", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001743 ;
    owl:annotatedTarget "Any variation in the division of the eukaryotic cell nucleus to produce two daughter nuclei that contain the identical chromosome complement of their mother compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000159 ;
    owl:annotatedTarget "OBSOLETE: Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas)." .

[]
    oboInOwl:hasDbXref "GO:0007155", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001744 ;
    owl:annotatedTarget "Any variation in the attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix compared to control." .

[]
    oboInOwl:hasDbXref "GO:0032154", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000160 ;
    owl:annotatedTarget "Embryos do not form a defined shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis." .

[]
    oboInOwl:hasDbXref "GO:0005912", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001745 ;
    owl:annotatedTarget "Any variation in a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control." .

[]
    oboInOwl:hasDbXref "GO:0005923", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001746 ;
    owl:annotatedTarget "Any perturbation in the belt-like region of very close contact between the plasma membranes of adjacent cells that results in the complete occlusion of the intercellular space." .

[]
    oboInOwl:hasDbXref "GO:0010043", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001747 ;
    owl:annotatedTarget "Animals exhibit variations in the change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031910", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001748 ;
    owl:annotatedTarget "The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031911", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001749 ;
    owl:annotatedTarget "The toxic response to zinc occurs at a lower concentration or a shorter exposure compared to control animals. In C. elegans hypersensitive animals exhibit delayed development or lethality at concentrations of zinc (e.g. ZnSO4), which has little or no effect on control worms." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031911", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001750 ;
    owl:annotatedTarget "Animals fail to exhibit toxicity to the concentration of zinc that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to zinc include delayed development or lethality." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001751 ;
    owl:annotatedTarget "Animals exhibit increased lethality as a result of exposure to environments with a higher solute concentration than their own internal environment, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0016192", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001752 ;
    owl:annotatedTarget "Animals exhibit variations in vesicle-based directed movement of substances into, out of, or within a cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004883", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001753 ;
    owl:annotatedTarget "Animals exhibit intensified accumulation of fluids or fluorescent markers etc. within their coelomocytes compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029049", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001754 ;
    owl:annotatedTarget "Contents of endosomes fail to be transported to lysosomal compartments." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028948", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001755 ;
    owl:annotatedTarget "Animals do not arrest mitotic germ cell division, as control animals, when treated with UV radiation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028948", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001756 ;
    owl:annotatedTarget "Programmed cell death caused by UV radiation is reduced compared to control animals. In C. elegans, this is often measured in the pachytene region of the gonad." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001757 ;
    owl:annotatedTarget "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of signalling peptides in the organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001758 ;
    owl:annotatedTarget "Variations in the chemical reactions and pathways involved in the formation and maturation of specialized peptidergic neurotransmitters encoded as preproproteins that are posttranslationally processed to yield bioactive neuropeptides compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "GO:0016070", "WB:WBPaper00028915", "WB:WBPaper00031962", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001759 ;
    owl:annotatedTarget "Variations in the biogenesis or stability of the 21U-RNA class of molecules compared to control. Molecules are classified as 21U-RNA based on the presence of a 5'U and a conserved upstream motif, which may specify the production of these molecules, in addition these molecules are typically 21nt in length." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031945", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001760 ;
    owl:annotatedTarget "Animals exhibit an increase in the rate of deletion events in mono-G or G-rich tracts within the genome compared to control." .

[]
    oboInOwl:hasDbXref "GO:0016199", "WB:WBPaper00032007", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001761 ;
    owl:annotatedTarget "Regulated ventral midline crossing by axons vary either in the frequency of crossing events or the maintenance through development of process positions compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003831", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001762 ;
    owl:annotatedTarget "Yolk is not taken up by oocytes in the same manner or to the same degree as observed for control animals. This often leads to an accumulation of yolk in the pseudocoelom." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004883", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001763 ;
    owl:annotatedTarget "Uptake of subtances from the intestine is altered from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001764 ;
    owl:annotatedTarget "Animals exhibit variations in their response to carbon dioxide compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031935", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001765 ;
    owl:annotatedTarget "Variations in the characteristic movement away from specific CO2 levels compared to control. C. elegans avoids high levels of CO2." .

[]
    oboInOwl:hasDbXref "GO:0042632", "WB:WBPaper00026641", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001766 ;
    owl:annotatedTarget "Animals are more sensitive to the reduction of cholesterol in the environment compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032007", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001767 ;
    owl:annotatedTarget "Outgrowth of the commissure occurs on the side of the body different from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032007", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001768 ;
    owl:annotatedTarget "Variations in the quantity of circumferential axonal tracts from the number observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032049", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001769 ;
    owl:annotatedTarget "Animals fail to silence cytoplasmic-localized RNAs. Nuclear-localized RNAs may still be sensitive to RNAi." .

[]
    oboInOwl:hasDbXref "GO:0035197", "WB:WBPaper00032049", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001770 ;
    owl:annotatedTarget "Animals exhibit variations in their selective interactions with small interfering RNA molecules compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031932", "WB:WBPaper00032049", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001771 ;
    owl:annotatedTarget "Animals exhibit variations in the length or amount of any endogenous small interfering RNA molecule populations compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031962", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001772 ;
    owl:annotatedTarget "Animals exhibit an increase in the levels of transposase mRNA, from endogenous transposons, over that measured in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031965", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001773 ;
    owl:annotatedTarget "Animals do not exhibit an increase in speed when placed in an environment that relies on a combination of swimming and crawling behaviors compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005123", "WB:WBPaper00032090", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001774 ;
    owl:annotatedTarget "An epidermal enclosure defect that results in internal organs lying on the outside of the embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028750", "WB:WBPaper00031942", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001775 ;
    owl:annotatedTarget "Pre-treatment with stress-inducing temperatures does not result in a life-span extension as it does in control animals." .

[]
    oboInOwl:hasDbXref "GO:0035047", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000161 ;
    owl:annotatedTarget "Any variation in the rotation of centrosomes and associated pronuclei in one-cell embryo, occurring as a transition between pronuclear migration and pronuclear fusion compared to control." .

[]
    oboInOwl:hasDbXref "GO:0016070", "WB:WBPaper00028915", "WB:WBPaper00031962", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001776 ;
    owl:annotatedTarget "Variations in the biogenesis and stability of the small interfering class of RNA molecules compared to control. In C. elegans these molecules are antisense to mRNA's and may be processed from long double-stranded RNA." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032049", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001777 ;
    owl:annotatedTarget "Animals exhibit an increase in the levels of nuclear mRNA species compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032049", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001778 ;
    owl:annotatedTarget "Animals fail to silence nuclear-localized RNAs. Animals still retain sensitivity to RNAi for those RNAs located outside of the nucleus." .

[]
    oboInOwl:hasDbXref "GO:0035196", "WB:WBPaper00028915", "WB:WBPaper00029181", "WB:WBPaper00030747", "WB:WBPaper00031962", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001779 ;
    owl:annotatedTarget "Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029060", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001780 ;
    owl:annotatedTarget "Variations in the behavioral plasticity induced by the integration of two sensory signals compared to control. In C. elegans animals exhibit enhancement of butanone chemotaxis by preexposure to butanone and food." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031945", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001781 ;
    owl:annotatedTarget "Animals are more susceptible than control animals to the effects of a nucleic acid damaging agent. This increased susceptibility is often measured by an increase in the rate of spontaneous mutations or an increased lethality." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031981", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001782 ;
    owl:annotatedTarget "Response to trace levels of oxygen is reduced or weakened compared to the response of control animals." .

[]
    oboInOwl:hasDbXref "GO:0022834", "WB:WBPaper00031930", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001783 ;
    owl:annotatedTarget "Animals exhibit variations in the actions of a channel that catalyses the transmembrane transfer of a cation when acetylcholine has been bound by the channel complex or one of its constituent parts compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0007040", "WB:WBPaper00029049", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001784 ;
    owl:annotatedTarget "OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031974", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001785 ;
    owl:annotatedTarget "Animals are deficient in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms." .

[]
    oboInOwl:hasDbXref "GO:0045161", "WB:WBPaper00031930", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001786 ;
    owl:annotatedTarget "Animals exhibit variations in the targeting, clustering and or maintenance of ion channels in distinct subcellular domains of the neuron compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031999", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001787 ;
    owl:annotatedTarget "Animals do not respond via directed movement to light stimuli in the same manner as control animals. In C. elegans, animals move away from light." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031934", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001788 ;
    owl:annotatedTarget "Animals survive longer than control animals after or during exposure to DNA damaging agents." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031942", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001789 ;
    owl:annotatedTarget "Life span of the animal is not influenced by changes in temperature in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032060", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001790 ;
    owl:annotatedTarget "Cooling or warming evoked changes in membrane currents are not observed." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002315", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001791 ;
    owl:annotatedTarget "Animals exhibit variations in temperature dependent differences in the length of their defecation cycle. In C. elegans the length of the cycle is the same at different temperatures, showing temperature compensation." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001792 ;
    owl:annotatedTarget "Nuclei of specific cells are smaller compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002776", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001793 ;
    owl:annotatedTarget "The anterior body contraction and expulsion steps of the defecation cycle are absent; posterior body contractions are still present." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031914", "WB:WBPaper00032172", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001794 ;
    owl:annotatedTarget "Discrete foci within the cytoplasm containing congregations of mRNA translational suppression and degradation mechanisms vary in their arrangement, clustering or are otherwise not well-defined compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031859", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001795 ;
    owl:annotatedTarget "Animals exhibit variations in repeat lengths of microsatellite genomic sequences compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031868", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001796 ;
    owl:annotatedTarget "Animals exhibit increased sensitivity to interstrand cross-linking agents, such as HN2 (nitrogen mustard) and CDDP (cisplatin) compared to control. In C. elegans, increased sensitivity to these agents is often observed as a decrease in survival compared to control animals after exposure to the agent." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031914", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001797 ;
    owl:annotatedTarget "Germline nuclei do not progress through pachytene to diplotene." .

[]
    oboInOwl:hasDbXref "GO:0051964", "WB:WBPaper00032163", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001798 ;
    owl:annotatedTarget "The processes that inhibit the location or frequency of formation of synapses are downregulated resulting in the formation of synapses or synapse-like structures in areas of the neuron that are typically devoid of synapses in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000162 ;
    owl:annotatedTarget "Larva show deficiencies in chroma resulting in increased translucency." .

[]
    oboInOwl:hasDbXref "GO:0051964", "WB:WBPaper00032163", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001799 ;
    owl:annotatedTarget "The processes that inhibit the location or frequency of formation of synapses are upregulated compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031865", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001800 ;
    owl:annotatedTarget "Changes in the levels of innate immune gene products in response to pathogen exposure are significantly different from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032163", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001801 ;
    owl:annotatedTarget "Animals fail to establish or maintain characteristics that delineate the dendrite from the axon. The exclusion of presynaptic components from the dendrite is one indication of axodendritic polarity." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032190", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001802 ;
    owl:annotatedTarget "Animals fail to relax their body wall muscles to the same extent as muscles in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032168", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001803 ;
    owl:annotatedTarget "Animals exhibit variations in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032168", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001804 ;
    owl:annotatedTarget "Animals exhibit a decrease in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by decreases in the number of Nile Red or BODIPY 493/503 staining bodies." .

[]
    oboInOwl:hasDbXref "GO:0007005", "WB:WBPaper00032231", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001805 ;
    owl:annotatedTarget "Inner membrane of mitochondria are disconnected and form vesicular bodies." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029085", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001806 ;
    owl:annotatedTarget "Any variation in the ability of a protein to resist disintegration via chemical or physical modifications compared to control." .

[]
    oboInOwl:hasDbXref "GO:0000380", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001807 ;
    owl:annotatedTarget "Any variation in the process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032272", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001808 ;
    owl:annotatedTarget "The degradation of genomic and or cellular material of the corpse does not occur at the same rate or under the same conditions as observed in control animals undergoing cell death." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032272", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001809 ;
    owl:annotatedTarget "The formation of mature intracellular compartments via membrane fusion is disrupted." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028947" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001810 ;
    owl:annotatedTarget "Animals exhibit variations in the partitioning of oocytes from each other compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031915", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001811 ;
    owl:annotatedTarget "Animals retain a significantly greater proportion of their fat upon serotonin treatment, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001812 ;
    owl:annotatedTarget "During development of the embryo, the epidermis loses integrity and the contents of the embryo are expelled." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032296", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001813 ;
    owl:annotatedTarget "Animals exhibit defects in the stabilization of homologue pairing, which occurs through the initiation and formation of the synaptonemal complex, during meiosis." .

[]
    oboInOwl:hasDbXref "GO:0051026", "WB:WBPaper00032296", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001814 ;
    owl:annotatedTarget "Animals exhibit defects in the number or extent of connections between chromatids that occur during the process of genetic material exchange between homologous segments of non-sister chromatids." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032296", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001815 ;
    owl:annotatedTarget "Animals exhibit defects in the asymmetric diassembly of the synaptonemal complex during progression through meiosis." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032221", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001816 ;
    owl:annotatedTarget "Neuromuscular signaling between neurons and egg laying musculature varies from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032335", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001817 ;
    owl:annotatedTarget "The conditioned aversion to a specific chemical compound as a result of that compound being coupled with an unfavorable condition, such as starvation, does not increase to the same extent as observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032221", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001818 ;
    owl:annotatedTarget "Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032196", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001819 ;
    owl:annotatedTarget "The number of pathogens associated with the animal vary from that associated with control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003187", "WB:WBPaper00032342", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001820 ;
    owl:annotatedTarget "Animals tend to accumulate at the thickest part of the bacterial lawn." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032342", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001821 ;
    owl:annotatedTarget "Animals do not accumulate at the thickest part of the bacterial lawn. Animals do not preferentially deplete bacterial food at the thicker parts of the lawn." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032517", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001822 ;
    owl:annotatedTarget "Animals produce pheromone but it does not undergo controlled release into the environment." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028527", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001823 ;
    owl:annotatedTarget "Any variation in the mechanism by which sperm find their correct target destinations (spermatheca)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005486", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001824 ;
    owl:annotatedTarget "Animals exhibit variations in any process necessary for the progression through prophase during meiosis compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005486", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001825 ;
    owl:annotatedTarget "Animals have very few or no germline nuclei and gonad arms that are very small or missing." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032091", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001826 ;
    owl:annotatedTarget "Variations in the regulated breakdown of RNA species via the action of cellular enzymes (RNases) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004325", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001827 ;
    owl:annotatedTarget "Variations in any process that involves the maintenance, biosynthesis or accumulation of RNA in the organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004325", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001828 ;
    owl:annotatedTarget "Variations in the persistence of an RNAi induced phenotype compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033007", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001829 ;
    owl:annotatedTarget "Any variation that results in the premature differentiation of spermatids into motile spermatozoa compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031874", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001830 ;
    owl:annotatedTarget "Any variation in an animal's response to exposure to multiple stressors occuring simultaneously or during an overlapping temporal window compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025171", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001831 ;
    owl:annotatedTarget "Any variation in the formation of intestinal microvilli. Microvilli are actin-based cellular structures that form plasma membrane projections into the extracellular space and whose specialized shape provides increased cellular surface area. Microvilli are a crucial component of the terminal differentiation process for many epithelial cell types, usually ones that play an absorptive or filtering role." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000163 ;
    owl:annotatedTarget "Larva appear unusually transparent when compared to control." .

[]
    oboInOwl:hasDbXref "GO:0005643", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001832 ;
    owl:annotatedTarget "Any variation that disrupts the assembly, distribution, localization or organization of any of the numerous similar discrete openings in the nuclear envelope, where the inner and outer nuclear membranes are joined." .

[]
    oboInOwl:hasDbXref "GO:0005215", "WB:WBPaper00025137", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001833 ;
    owl:annotatedTarget "Any variation in the directed movement of substances in a cell, from one side of a membrane to another, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0008380", "WB:WBPaper00032287", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001834 ;
    owl:annotatedTarget "Variations in the processes regulating the excision of intervening introns from the primary mRNA transcript, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032936", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001835 ;
    owl:annotatedTarget "Variations in the amount of energy consumed by an organism compared to control. Energy expenditure is often determined by assaying oxygen consumption." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033072", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001836 ;
    owl:annotatedTarget "Any variation in the overall structure or appearance of the protective barrier which isolates the embryo from the external environment, compared to control ." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032936", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001837 ;
    owl:annotatedTarget "Life span of the animal is not influenced by changes in diet in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033094", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001838 ;
    owl:annotatedTarget "Gene expression of an animal is not influenced by drug treatment in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033094", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001839 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of phorbol esters that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Phorbol esters such as PMA act as DAG mimetics." .

[]
    oboInOwl:hasDbXref "GO:0042060", "WB:WBPaper00033094", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001840 ;
    owl:annotatedTarget "Variations in the processes that restore integrity to a damaged tissue following an injury, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0019932", "WB:WBPaper00033456", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001841 ;
    owl:annotatedTarget "Any variation in a series of molecular signals that help relay a receptor mediated signal within the cell, compared to control. Second messengers often comprise of ions (eg: Ca2+) or small molecules (cGMP, cAMP etc) that are formed or released into the cytosol." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033168", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001842 ;
    owl:annotatedTarget "Any variation in the state or activity of an organism as a result of abrupt discontinuation or decreased dosage of a drug, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0042445", "WB:WBPaper00034639", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001843 ;
    owl:annotatedTarget "Animals exhibit variations in any process that involves the degradation, biosynthesis or accumulation of hormones within the organism compared to control. Hormones are naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone." .

[]
    oboInOwl:hasDbXref "GO:0050994", "WB:WBPaper00033126", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001844 ;
    owl:annotatedTarget "Variations in the process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0030258", "WB:WBPaper00034639", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001845 ;
    owl:annotatedTarget "Variations in the covalent alteration of one or more components (eg: fatty acids, sterols etc.) in a lipid, resulting in a change in the properties of the lipid, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0001845", "WB:WBPaper00031805", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001846 ;
    owl:annotatedTarget "Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00034639", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001847 ;
    owl:annotatedTarget "Variations in the processes that facilitate/permit dauer entry when exposed to specific sterol molecules, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0035239", "WB:WBPaper00033081", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001848 ;
    owl:annotatedTarget "Variations in the process by which the anatomical structures of a tube are generated and organized, compared to control. Morphogenesis pertains to the creation of form or shape." .

[]
    oboInOwl:hasDbXref "GO:0006882", "WB:WBPaper00033166", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001849 ;
    owl:annotatedTarget "Variations in the regulation of levels, transport, and metabolism of zinc ions within an organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032243", "WB:WBPaper00032356", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001850 ;
    owl:annotatedTarget "Programmed cell death of germ cells caused by exposure to ionizing energy does not occur to the same extent as it does in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027700", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001851 ;
    owl:annotatedTarget "Animals exhibit variations in radiation induced non-apoptotic death of multipotential precursor cells or tissues (clonogens) compared to control. Elimination of clonogens results in normal tissue damage as well as solid-tumor eradication." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035074", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001852 ;
    owl:annotatedTarget "Animals exhibit variations in their response to an agent that destroys or causes the expulsion of parasitic intestinal worms compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035150", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001853 ;
    owl:annotatedTarget "Animals exhibit variations in their response to the amino-acetonitrile derivatives (AADs) class of synthetic anthelmintics, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000164 ;
    owl:annotatedTarget "Animals exhibit a reduced girth compared to a control animal of the same developmental stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035150", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001854 ;
    owl:annotatedTarget "Animals exhibit variations in their response to the microtubule-depolymerizing drug benomyl, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035174", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001855 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of fluoride ions that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to fluoride ions to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035150", "WB:WBPaper00035194", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001856 ;
    owl:annotatedTarget "Animals exhibit variations in their response to ivermectin, an agonist of glutamate-gated chloride channels, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035315", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001857 ;
    owl:annotatedTarget "Gene expression of an animal is not influenced by the exposure to disease causing agents in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031692", "WB:WBPaper00034683", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001858 ;
    owl:annotatedTarget "Animals fail to suppress head oscillations in response to anterior touch. In C. elegans, this behavior is a result of tyraminergic signaling." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025096" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasRelatedSynonym ;
    owl:annotatedSource obo:WBPhenotype_0001858 ;
    owl:annotatedTarget "Sho" .

[]
    oboInOwl:hasDbXref "GO:0042714", "WB:WBPaper00035328", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001859 ;
    owl:annotatedTarget "Any variation in the aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0032456", "WB:WBPaper00035466", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001860 ;
    owl:annotatedTarget "Variations in the directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035435", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001861 ;
    owl:annotatedTarget "Gene expression of an animal is not influenced by environmental changes in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "GO:0030026", "WB:WBPaper00035485", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001862 ;
    owl:annotatedTarget "Variations in the regulation of levels, transport, and metabolism of manganese ions within an organism compared to control." .

[]
    oboInOwl:hasDbXref "GO:0010042", "WB:WBPaper00035485", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001863 ;
    owl:annotatedTarget "Animals exhibit variations in their response to manganese compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0051223", "WB:WBPaper00035491", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001864 ;
    owl:annotatedTarget "Any variation in the processes that modulate the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore compared to control." .

[]
    oboInOwl:hasDbXref "GO:0016567", "WB:WBPaper00035602", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001865 ;
    owl:annotatedTarget "Variations in the process by which one or more ubiquitin moieties are added to a protein, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0009617", "GO:0045087", "WB:WBPaper00035215", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001866 ;
    owl:annotatedTarget "Animals exhibit a reduction in pathogen accumulation, persistent colonization, and luminal distension of the intestine." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032910", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001867 ;
    owl:annotatedTarget "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a mitotic cell cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032910", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001868 ;
    owl:annotatedTarget "Cells undergoing meiosis exhibit defects in the overall function or activity of the meiotic spindle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032910", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001869 ;
    owl:annotatedTarget "Cells undergoing meiosis exhibit defects in the positioning of the meiotic spindle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032910", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001870 ;
    owl:annotatedTarget "Cells undergoing meiosis exhibit defects in the rotation of the meiotic spindle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035656", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001871 ;
    owl:annotatedTarget "Life span of the animal is not influenced by drug exposure in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035656", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001872 ;
    owl:annotatedTarget "Locomotion of the animal is not influenced by drug exposure in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032910", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001873 ;
    owl:annotatedTarget "Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the meiotic spindle, the array of microtubules and associated molecules that serves to move duplicated and/or homologous chromosomes apart." .

[]
    oboInOwl:hasDbXref "GO:0045116", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001874 ;
    owl:annotatedTarget "Any variation in the conjugation of the ubiquitin-like protein Nedd8 to another protein compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001875 ;
    owl:annotatedTarget "Chromosomal masses fail to fully separate and remained linked during anaphase." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001876 ;
    owl:annotatedTarget "Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome." .

[]
    oboInOwl:hasDbXref "GO:0005634", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001877 ;
    owl:annotatedTarget "Any variation in the structure, form or composition of the membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001878 ;
    owl:annotatedTarget "Animals exhibit variations in the response to the addition of hydroxyurea compared to that observed in control animals. Hydroxyurea stops DNA from being replicated." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001879 ;
    owl:annotatedTarget "Animals respond to hydroxyurea at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0000768", "GO:0045026", "WB:WBPaper00005122", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000165 ;
    owl:annotatedTarget "Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing." .

[]
    oboInOwl:hasDbXref "GO:0005783", "WB:WBPaper00025163", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001880 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025163", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001881 ;
    owl:annotatedTarget "Any variation in the normally asymmetric distribution of the endoplasmic reticulum during cell divisions of the early embryo. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032450", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001882 ;
    owl:annotatedTarget "Any variation in the number of chromosomes in a cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024200", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001885 ;
    owl:annotatedTarget "Embryos exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000166 ;
    owl:annotatedTarget "Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024200", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001886 ;
    owl:annotatedTarget "Embryos exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032974", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001887 ;
    owl:annotatedTarget "Animals execute supernumerary cell divisions during the development of the lateral, alae-producing epithelial cells, resulting in a larger number of these cells than control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035972", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001888 ;
    owl:annotatedTarget "Animals exhibit an increase in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by increases in the number of BODIPY 493/503 staining." .

[]
    oboInOwl:hasDbXref "GO:0030017", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001889 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001890 ;
    owl:annotatedTarget "Any variation in the attachment plaque for thin filaments onto the cell membrane. The dense body in body wall muscles is especially large, indenting far into the cytoplasm to border each sarcomere, thus providing a long row of coherent attachment sites at regular intervals (WormAtlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001891 ;
    owl:annotatedTarget "Animals exhibit variations in the form, structure or composition of a planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000167 ;
    owl:annotatedTarget "Seam cells fuse to form a continuous syncytium along the body wall at an earlier stage of development compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033086", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001892 ;
    owl:annotatedTarget "Any variation in the levels of the polymerized form of glucose throughout the body of the animal as compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033162", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001893 ;
    owl:annotatedTarget "Any reduction in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033438", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001894 ;
    owl:annotatedTarget "Animals exhibit variations in the number of nuclei contained in a particular cell type compared to control." .

[]
    oboInOwl:hasDbXref "GO:0007344", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001895 ;
    owl:annotatedTarget "Parental chromosomes fail to undergo appropriate mixing upon pronuclear fusion resulting in a zygotic nucleus in which parental genomes remain segregated." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036343", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001896 ;
    owl:annotatedTarget "Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0009416", "WB:WBPaper00032087", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001897 ;
    owl:annotatedTarget "Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus (electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00034684", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001898 ;
    owl:annotatedTarget "Variations in the process by which sister chromatids, identical chromosomes resulting from DNA replication, are physically separated during the meiotic cell cycle, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0006749", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001899 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of glutathione compared to control animals at a defined stage. Glutathione, the tripeptide glutamylcysteinylglycine, acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00034717", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001900 ;
    owl:annotatedTarget "Animals exhibit a decrease in the cellular levels of reduced glutathione (GSH), compared to control. Reduced levels of GSH may be an indication of susceptibility to oxidative stress." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001901 ;
    owl:annotatedTarget "Animals exhibit variations in the formation or disassembly of fat containing organelles compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00034742", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001902 ;
    owl:annotatedTarget "Animals exhibit an increase in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001903 ;
    owl:annotatedTarget "Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix).  The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035259", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001904 ;
    owl:annotatedTarget "Animals fail to exhibit toxicity to the concentration of manganese that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to manganese include dopamine (DA) neuron neurodegeneration." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035252", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001905 ;
    owl:annotatedTarget "Animals lay fewer total number of eggs over the lifetime of the animal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003991", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001906 ;
    owl:annotatedTarget "During epidermal morphogenesis, hypodermal cells do not properly undergo the characteristic cell shape changes necessary for the embryo to elongate." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003991", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001907 ;
    owl:annotatedTarget "Animals exhibit defects in the generation of the dorsal epithelial sheet, which entails distinct cell shape changes and movements to affect the interdigitation of two rows of dorsal cells resulting in a single row of cells across the dorsal midline." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003991", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001908 ;
    owl:annotatedTarget "The animal displays defects in any step of the ventral enclosure process resulting an embryo that is not enclosed and or with interior cells protruding out of the embryo." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001909 ;
    owl:annotatedTarget "OBSOLETE. Any variation in the prevention of mRNA translation that normally occurs in certain cells, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0051383", "WB:WBPaper00035270", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001910 ;
    owl:annotatedTarget "Animals exhibit variations in the assembly, arrangement, orientation, or disassembly of the kinetochore, a multisubunit protein complex on chromosomes where the spindle fibers attach during cell division to pull the chromosomes apart." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001911 ;
    owl:annotatedTarget "Animals do not regrow axons following axon loss or damage, to the same extent, or in the same manner as observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035290", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001912 ;
    owl:annotatedTarget "The number of coelomocytes are reduced compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035290", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001913 ;
    owl:annotatedTarget "The number of coelomocytes are increased compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035290", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001914 ;
    owl:annotatedTarget "Animals contain fewer pharyngeal cells compared to control animals.  In C. elegans, pharyngeal cells are derived from MS-blastomere." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035290", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001915 ;
    owl:annotatedTarget "Any variation that results in the cellular expression of an mRNA in cells/tissues, that is otherwise not observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035289", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001916 ;
    owl:annotatedTarget "Pathogens internally associated with the animal exhibit an increase in survival compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0006473", "WB:WBPaper00025192", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001917 ;
    owl:annotatedTarget "Variations in the processes that incorporate acetyl groups to one or more amino acids within a protein, compared to control. An acetyl group is CH3CO-." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001918 ;
    owl:annotatedTarget "Animals respond to a specific chemical at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035924", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001919 ;
    owl:annotatedTarget "Animals exhibit larger inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00030736", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001920 ;
    owl:annotatedTarget "The growth of pharyngeal components occurs in a radial fashion around the longitudinal axis of the worm as demonstrated by bent radial contractile arrays within the pharyngeal muscle cells. The defect is more pronounced as development progresses resulting in a more obvious twisting phenotype. Depending on the allele, the twist can be right-handed or left-handed" .

[]
    oboInOwl:hasDbXref "GO:0042138", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001921 ;
    owl:annotatedTarget "Any variation in the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination." .

[]
    oboInOwl:hasDbXref "GO:0008088", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001922 ;
    owl:annotatedTarget "Any variation in the directed movement of organelles or molecules along microtubules in nerve cell axons." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00034768" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001923 ;
    owl:annotatedTarget "The population of the lateral, alae-producing epithelial cells (seam cells) is reduced compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001924 ;
    owl:annotatedTarget "Oocytes are found one on top of the other in the dorsal to ventral orientation in the gonad." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001925 ;
    owl:annotatedTarget "Oocytes are no longer arranged in the gonad in the same manner as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027739", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001926 ;
    owl:annotatedTarget "Basal contraction rate and or peak contraction rate of the gonadal sheath is increased relative to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033102", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001927 ;
    owl:annotatedTarget "Animals produce an excess number of distal tip cells compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033102", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001928 ;
    owl:annotatedTarget "Animals produce an excess number of gonad arms compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033102", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001929 ;
    owl:annotatedTarget "The gonads of male animals do not produce the linker cell involved in guiding the developing male gonad to the sex organs in the male tail." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032907", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001930 ;
    owl:annotatedTarget "Animals extend altered or fewer numbers of dorsal and or ventral muscle arms compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032907", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001931 ;
    owl:annotatedTarget "The morphology or number of connections between muscle arms and commissural motor axons varies from control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032907", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001932 ;
    owl:annotatedTarget "Animals exhibit ectopic plasma membrane extensions from muscle, these extensions are random projections that are thinner than the typical muscle arm." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035070", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001933 ;
    owl:annotatedTarget "The pattern of localization of presynaptic markers is disrupted compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036485", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001934 ;
    owl:annotatedTarget "Any variation in the extension of vulval muscles compared to control.  In C. elegans contralateral vulval muscles fail to meet at the midline." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033115", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001935 ;
    owl:annotatedTarget "Animals become paralyzed in response to aggregation of proteins like poly-glutamine or beta-amyloid." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033115", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001936 ;
    owl:annotatedTarget "Animals fail to respond to the aggregation of proteins that elicits a paralysis response in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033115", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001937 ;
    owl:annotatedTarget "Animals respond to protein aggregation at a lower concentration of aggregates or in less time compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0006281", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001938 ;
    owl:annotatedTarget "Any variation in the process of restoring DNA after damage.  DNA damage can be caused by a many chemical or physical agents, and this damage is repaired by a variety  of different DNA repair pathways." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035961", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001939 ;
    owl:annotatedTarget "Animals are not repelled by bitter tastants such as quinine, primaquine quinacrine etc., to the same extent as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031889", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001940 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001941 ;
    owl:annotatedTarget "The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001942 ;
    owl:annotatedTarget "The nucleus-free core of germline cytoplasm in the gonad is missing." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001943 ;
    owl:annotatedTarget "The width of the nucleus-free core of germline cytoplasm in the gonad is larger compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001944 ;
    owl:annotatedTarget "A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001945 ;
    owl:annotatedTarget "The size of haploid female germ cells (oocytes) are significantly smaller compared to control." .

[]
    oboInOwl:hasDbXref "GO:0000239", "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001946 ;
    owl:annotatedTarget "Developing oocytes show defects in their entry, progression through or exit from the pachytene stage compared to control animals. Pachytene is a cell cycle process comprising the steps by which a cell progresses through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." .

[]
    oboInOwl:hasDbXref "GO:0000240", "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001947 ;
    owl:annotatedTarget "Developing oocytes show defects in their entry, progression through or exit from the diplotene stage compared to control animals. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." .

[]
    oboInOwl:hasDbXref "GO:0000241", "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001948 ;
    owl:annotatedTarget "Developing oocytes show defects in their entry, progression through or exit from the diakinesis stage compared to control animals. Diakinesis is a cell cycle process comprising the steps by which a cell progresses through the final stage of prophase I in meiosis; the transition to meiotic metaphase I." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001949 ;
    owl:annotatedTarget "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diakinesis stage. In C. elegans the diakinesis region occurs in the proximal gonad arm and is preceded by the diplotene region. In the diakinesis region oocytes arrest until oocyte maturation occurs." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001950 ;
    owl:annotatedTarget "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001951 ;
    owl:annotatedTarget "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001952 ;
    owl:annotatedTarget "Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001953 ;
    owl:annotatedTarget "Nuclei have fallen out of developing germ cell compartments into the rachis." .

[]
    oboInOwl:hasDbXref "GO:0000240", "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001954 ;
    owl:annotatedTarget "The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001955 ;
    owl:annotatedTarget "Haploid female germ cells (oocytes) contain more than one nucleus." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001956 ;
    owl:annotatedTarget "Haploid female germ cells (oocytes) lack a nucleus." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004833", "WB:WBPaper00025242", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000168 ;
    owl:annotatedTarget "Variations in the regulated release of proteins needed for alae formation by epidermal seam cells compared to control. Alae are small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (WormAtlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001957 ;
    owl:annotatedTarget "A decrease in size of the specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001958 ;
    owl:annotatedTarget "Animals contain a gonad that initially functioned, but subsequently stopped.  In hermaphrodites or females there is often the presence old embryos and/or hatched larva, but no young embryos, in the uterus." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031928", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001959 ;
    owl:annotatedTarget "Pulling forces on the astral microtubules at the spindle poles vary from that observed for control spindles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031928", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001960 ;
    owl:annotatedTarget "The spindle in the early embryo is aberrant in the characteristic posterior aster oscillations that occur along the transverse longitudinal axis of the spindle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031688", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001961 ;
    owl:annotatedTarget "Animals continue to produce progeny significantly past the time reproduction stops in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026603", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001962 ;
    owl:annotatedTarget "Animals produce less distal tip cells compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032269", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001963 ;
    owl:annotatedTarget "The association of homologs during diakinesis and the maintenance of their association through meiosis I as well as the preservation of centromeric cohesin between sister chromatids does not proceed as it does in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032147", "WB:WBPaper00036201", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001964 ;
    owl:annotatedTarget "Animals exhibit differential regulation of the dopaminergic fate among the various classes of dopaminergic neurons." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001965 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of the cell, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0010458", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000169 ;
    owl:annotatedTarget "Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037899", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001966 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of within the cell, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032269", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001967 ;
    owl:annotatedTarget "Animals differ from control animals in the length of or mechanics of the steps that culminate in the preservation and subsequent disassembly of the synaptonemal complex, the specification of bivalent arms, and proper cohesion of sister chromatids." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026603", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001968 ;
    owl:annotatedTarget "All somatic gonad precursor (SGP) daughters adopt a proximal fate resulting in an increase in the number of AC precursor cells at the expense of distal tip cells (DTC), which are thereby absent." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001969 ;
    owl:annotatedTarget "Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis).  These compartments eventually undergo cellularization and become oocytes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001970 ;
    owl:annotatedTarget "Germ cell compartments contain an an atypical number on nuclei compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001971 ;
    owl:annotatedTarget "Germ cell compartments do not contain a nucleus." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001972 ;
    owl:annotatedTarget "Germ cell compartments contain multiple nuclei." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001973 ;
    owl:annotatedTarget "Any variation in germ cell compartment size compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001974 ;
    owl:annotatedTarget "Germ cell compartments are smaller than that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001975 ;
    owl:annotatedTarget "Germ cell compartments are larger than that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000016 ;
    owl:annotatedTarget "Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:cab", "pmid:3428573" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000170 ;
    owl:annotatedTarget "Formation of alae occurs earlier in development compared to control animals; In C. elegans, adult lateral alae are typically generated during the late L4 stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001977 ;
    owl:annotatedTarget "Any variation in the form or composition of the compartment partitions in the germline of females/hermaphrodites that exist when nuclei are still connected to a common cytoplasm (rachis), compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001978 ;
    owl:annotatedTarget "Animals lack germ cell partitions (germ cell compartments)." .

[]
    oboInOwl:hasDbXref "GO:0031982", "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001979 ;
    owl:annotatedTarget "Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001980 ;
    owl:annotatedTarget "Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001981 ;
    owl:annotatedTarget "The compartments of the germline do not increase in size." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038381", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001982 ;
    owl:annotatedTarget "Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038234", "WB:WBPerson363" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001983 ;
    owl:annotatedTarget "Variation of the time an individual spent on a patch of food (bacterial lawn) before leaving, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038105", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001984 ;
    owl:annotatedTarget "Animals exhibit axons with migration behaviors that differ from those observed in control animals after the axons cross a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038105", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001985 ;
    owl:annotatedTarget "Animals exhibit axons with migration behaviors that differ from those observed in control animals before the axons reach a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038168", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001986 ;
    owl:annotatedTarget "Animals undergo an irreversible high temperature-induced developmental arrest during the first larval stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001039", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001987 ;
    owl:annotatedTarget "Any variation in the measured levels of acetylcholinesterase (AChE) activity compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000514", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001988 ;
    owl:annotatedTarget "Animals respond to a detergent at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001989 ;
    owl:annotatedTarget "Animals respond to hypoxic (low oxygen levels) stress after a shorter exposure time compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001990 ;
    owl:annotatedTarget "Animals fail to respond to low amounts of oxygen that elicit a response in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001991 ;
    owl:annotatedTarget "Response to low levels of oxygen is reduced or weakened compared to the response of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006209", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001992 ;
    owl:annotatedTarget "Animals exhibit an increase in the number of somatic sheath cells surrounding each gonad arm compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006209", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001993 ;
    owl:annotatedTarget "Animals exhibit fewer somatic sheath cells surrounding each gonad arm, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001994 ;
    owl:annotatedTarget "Any variation in the establishment of left-right asymmetry of the body axis compared to controls." .

[]
    oboInOwl:hasDbXref "GO:0007049", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001995 ;
    owl:annotatedTarget "Cells of the animals exhibit variations in the progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals." .

[]
    oboInOwl:hasDbXref "GO:0070314", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001996 ;
    owl:annotatedTarget "Any variation in the cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence before entering the S phase, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003628", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001997 ;
    owl:annotatedTarget "The nucleus or nuclei are not positioned in a similar manner or pattern in the cell or syncytium to that observed in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038282", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001998 ;
    owl:annotatedTarget "Animals respond more severely to laser ablation than control animals subjected to the same laser ablation conditions." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038243", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0001999 ;
    owl:annotatedTarget "Animals behave differently from control animals in assays testing for the ability to resolve or respond to conflicting sensory inputs." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038487", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002000 ;
    owl:annotatedTarget "Animals that exhibit an increase in locomotion activity do not return to basal level locomotion activity at the same rate as that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00039786", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002001 ;
    owl:annotatedTarget "The number of synapses per unit area of a neuron differs in the animal compared to that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028464", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002002 ;
    owl:annotatedTarget "A cell or cell of the animal exhibits extra centrosomes (a subcellular body consisting of two centrioles embedded in a protein matrix) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002003 ;
    owl:annotatedTarget "Animals exhibit variations in steady-state levels of hydrogen peroxide (H2O2) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038098", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002004 ;
    owl:annotatedTarget "Animals exhibit defects in the flow rate or targeting of the cortical actomyosin network, which occurs during polarization as well as contraction of the contractile ring, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038098", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002005 ;
    owl:annotatedTarget "The tension of the cytoskeleton comprised of the actomyosin network differs from controls. This tension can be measured by laser-cutting of the actomyosin cytoskeleton and observing any differences the recoil velocity of cortex adjacent to the cut site." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031064", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002006 ;
    owl:annotatedTarget "Compared to controls, embryos exhibit variations in the part meiosis I in which homologous chromosomes separate and migrate away from each other." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038098", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002007 ;
    owl:annotatedTarget "Embryos display cortical protusions during cytokinesis." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002008 ;
    owl:annotatedTarget "Animals exhibit variations in the non-enzymatic glycosylation process of attaching a protein or lipid to a sugar molecule, compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0004175", "WB:WBPaper00040082", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002009 ;
    owl:annotatedTarget "Animals exhibit variations from controls in their protein degradation machinery, which functions through the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038098", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002010 ;
    owl:annotatedTarget "The dynamics of the replacement of old proteins by newly synthesized or modified proteins varies from that of control animals. This phenotype is often measured by fluorescence recovery after photobleaching (FRAP)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040151", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002011 ;
    owl:annotatedTarget "Animals exhibit a secondary vulval invagination that is anterior or posterior to the primary opening depending on the the inappropriate placement of daughter cells along the anterior/posterior axis during vulval development." .

[]
    oboInOwl:hasDbXref "GO:0070192", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002012 ;
    owl:annotatedTarget "Any variation in the process of chromosome organization that is involved in meiosis, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson101", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002013 ;
    owl:annotatedTarget "Chromosomes fails to pair with homologous chromosomes during the prophase stage of meiosis." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002014 ;
    owl:annotatedTarget "Any observed variation in the measurement of current across the cell membrane compared to measurements in control animals. Current is a flow of electric charge through a medium." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002015 ;
    owl:annotatedTarget "Any observed variation in the measurement of voltage across the cell membrane compared to measurements in control animals. Voltage is the difference in electric potential energy per unit charge between two points." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001481", "WB:WBPaper00005801", "WB:WBPerson101", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002016 ;
    owl:annotatedTarget "Failure to execute the characteristic response to biotin as defined by control animals. In C. elegans, biotin is typically an attractant." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002017 ;
    owl:annotatedTarget "Any variation in the ability of multipotent vulval precursor cells to respond to signals compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031488", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002018 ;
    owl:annotatedTarget "Seam cells fuse to form a continuous syncytium along the body wall at a later stage of development compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031804", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002019 ;
    owl:annotatedTarget "Adult animals display a smaller number of eggs inside the uterus compared to controls" .

[]
    oboInOwl:hasDbXref "GO:0019226", "WB:WBPaper00031592", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002020 ;
    owl:annotatedTarget "Transmission of the signal along the neuron varies from control.  This process includes the flow of information from the neuron cell body to the synapse and across to the postsynaptic cell." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031592", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002021 ;
    owl:annotatedTarget "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed at the synapse, which are independent of presynaptic inputs." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031592", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002022 ;
    owl:annotatedTarget "Calcium transients at presynaptic regions do not occur." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031592", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002023 ;
    owl:annotatedTarget "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed either at the cell body or the synaptic region, which are independent of presynaptic inputs." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031592", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002024 ;
    owl:annotatedTarget "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed in cell bodies, which are independent of presynaptic inputs." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038069", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002025 ;
    owl:annotatedTarget "The diameter, volume, or area taken up by a cell differs from that measured in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040149", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002026 ;
    owl:annotatedTarget "Animals differ from control animals in response to mechanical stimulation targeting different parts of the same cell. In N2 wild-type animals, response to touch near the ALM cell body is reduced compared with touch of the cell area near the second pharyngeal bulb." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025001", "WB:WBPaper00027764", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002027 ;
    owl:annotatedTarget "VPCs differentiate in the absence of inductive signals coming from the gonad." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040149", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002028 ;
    owl:annotatedTarget "Animals differ from controls in their electrical response to mechanical stimulus." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002029 ;
    owl:annotatedTarget "Variations in the regulation of levels, transport, and metabolism of metal ions within an organism compared to control." .

[]
    oboInOwl:hasDbXref "GO:0010960", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002030 ;
    owl:annotatedTarget "Variations in the regulation of levels, transport, and metabolism of magnesium ions within an organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038311", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002031 ;
    owl:annotatedTarget "Exposure to carbohydrate binding gene products result in an altered action in comparison to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038311", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002032 ;
    owl:annotatedTarget "Animals differ from controls in the range, specificity, or presence of targets for exogenously applied lectins." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038311", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002033 ;
    owl:annotatedTarget "Animals contain targets for exogenously applied lectins." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038311", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002034 ;
    owl:annotatedTarget "Animals are not observed to contain targets for exogenously applied lectins." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038311", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002035 ;
    owl:annotatedTarget "Exposure to lectin has no affect on the behavior, growth, or development of the animal compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038311", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002036 ;
    owl:annotatedTarget "Exposure to lectin results in altered behavior, growth, or development of the animal compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040620", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002037 ;
    owl:annotatedTarget "The appearance and association of components along the double lipid bilayer enclosing the nucleus differs from controls. The NE separates nuclear contents from the rest of the cytoplasm and includes the intermembrane space, perinuclear space." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031689" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002038 ;
    owl:annotatedTarget "Proteins show defects in their localization in the cilia compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038442", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002039 ;
    owl:annotatedTarget "Animals exhibit variation in the directed movement of organelles or molecules along microtubules from the cell periphery in nerve cell axons to the cell body, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038412", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002040 ;
    owl:annotatedTarget "Chromosomes are not segregated symmetrically during mitosis." .

[]
    oboInOwl:hasDbXref "GO:0008283", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000171 ;
    owl:annotatedTarget "Any aberrancy in the processes that govern expansion of cell populations compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040467", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002041 ;
    owl:annotatedTarget "Animals exhibit variation in timing or ability to molt." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040467", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002042 ;
    owl:annotatedTarget "Molting cycles do not occur in a temporally controlled manner and cannot be synchronized across a population." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002043 ;
    owl:annotatedTarget "The number of cross progeny produced by hermaphrodites is reduced compared to control hermaphrodites." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002044 ;
    owl:annotatedTarget "Hermaphrodites do not produce cross progeny." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002045 ;
    owl:annotatedTarget "Animals exhibit fewer cell corpses compared to controls at the same developmental life stage." .

[]
    oboInOwl:hasDbXref "GO:0055072", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002046 ;
    owl:annotatedTarget "Variations in the regulation of levels, transport, and metabolism of iron within an organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038249", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002047 ;
    owl:annotatedTarget "Animals exhibit variations in their response to muscimol compared to that observed in control animals. Muscimol is a GABA-A receptor agonist." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040740", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002048 ;
    owl:annotatedTarget "Animals survive longer, or do not respond to the same degree as control animals under similar conditions of abamectin exposure." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040740", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002049 ;
    owl:annotatedTarget "Animals are not affected to the same degree as control animals under similar conditions of abamectin exposure." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040740", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002050 ;
    owl:annotatedTarget "Animals are do not survive, or become paralyzed in the presence of abamectin." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040624", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002051 ;
    owl:annotatedTarget "The production or regulation of ascaroside molecule populations differs from that of control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040624", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002052 ;
    owl:annotatedTarget "Animals lack the ability to produce ascarosides that are capable of being produced in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003945", "WB:WBPaper00040740", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002053 ;
    owl:annotatedTarget "Animals fail to respond to or exhibit an attenuated response to ivermectin under conditions that elicits a response in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036046", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002054 ;
    owl:annotatedTarget "Animals exhibit an exaggerated response to magnesium compared to control animals exposed to similar concentrations." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036207", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002055 ;
    owl:annotatedTarget "Animals do not exhibit light-induced currrents to the same extent or with the same quality as control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002056 ;
    owl:annotatedTarget "Any variation in the specific actions or reactions of an organism causing an alteration in the ingestion of food compared to control animals.  In C. elegans the main food source is bacteria and alterations in eating behavior usually lead to malnutrition." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002057 ;
    owl:annotatedTarget "Animals respond to Bacillus thuringiensis toxins (Bt toxins) at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002058 ;
    owl:annotatedTarget "Animals are not affected to the same degree as control animals under similar conditions of pore forming toxin exposure." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002059 ;
    owl:annotatedTarget "Animals respond to pore forming toxins at a lower concentration or a shorter exposure compared to control animals. Increased susceptibility to pore forming toxins (e.g. Cry5B from Bacillus thuringiensis) is often measured by a decrease in the rate of survival in the presence of pore forming toxins compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002060 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of pore forming toxins that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0051312", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002061 ;
    owl:annotatedTarget "Any variation in the progressive decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002062 ;
    owl:annotatedTarget "The process of decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form is abolished." .

[]
    oboInOwl:hasDbXref "GO:0016458", "WB:WBPaper00041239", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002063 ;
    owl:annotatedTarget "Animals differ from controls in the expression of genes targeted for silencing (gene inactivation) in subsequent generations via transcriptional or post-transcriptional processes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041239", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002064 ;
    owl:annotatedTarget "Animals express genes that had been targeted for heritable silencing in previous generations." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038447", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002065 ;
    owl:annotatedTarget "Animals display variations in the manner in which the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) is remodeled, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038447", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002066 ;
    owl:annotatedTarget "Animals display variations in the manner in which an opening in the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) expands to make way for intertissue connections, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040757", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002067 ;
    owl:annotatedTarget "Animals differ from control animals in cortical actomyocin dynamics leading to internalization of endodermal precursor cells during gastrulation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040200", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002068 ;
    owl:annotatedTarget "There is significantly less difference between the number of astral microtubles or other component(s) of the spindle microtuble organizing center at the anterior versus posterior poles of the spindle, than observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040220", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002069 ;
    owl:annotatedTarget "Axons in animals do not end in the same manner as they do in control animals. Some defects described include an overextension of the axon or termination of the axon in the shape of a hook, either large or small." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038249", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002070 ;
    owl:annotatedTarget "Animals do not mimic control animals in their egg-laying response to muscimol exposure. In C. elegans, muscimol inhibits egg-laying." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038249", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002071 ;
    owl:annotatedTarget "The length of the animal does not increase to the same extent as observed for control animals, in response to exposure to muscimol." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038233", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002072 ;
    owl:annotatedTarget "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of carbohydrates within the organism or cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036046", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002073 ;
    owl:annotatedTarget "Animals exhibit variations in the regulation of levels, transport, and metabolism of cations within a cell or between a cell and its external environment, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040172", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002074 ;
    owl:annotatedTarget "Animals vary in the directed or coordinated movement of their centrosomes during cell division, compared to the pattern of movement observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0030703", "WB:WBPaper00031064", "WB:WBPaper00040142", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002075 ;
    owl:annotatedTarget "Embryos exhibit variations in the processes that lead to the construction of the eggshell, a protective structure that minimizes water loss whilst allowing gas exchanges essential for embryonic respiration, compared to controls" .

[]
    oboInOwl:hasDbXref "GO:0060471", "WB:WBPaper00031064", "WB:WBPaper00040142", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002076 ;
    owl:annotatedTarget "The process of secretion by a cell that results in the release of intracellular molecules contained within a specialized secretory vesicle that fuses with the plasma membrane during egg activation." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000172 ;
    owl:annotatedTarget "The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are increased." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038270", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002077 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of a dopamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038409", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002078 ;
    owl:annotatedTarget "The pattern or state of methyl modifications of histone varies from that of controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002079 ;
    owl:annotatedTarget "The animal's ability to reproduce, or start of reproduction occurs later than that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002080 ;
    owl:annotatedTarget "Animals exhibit variations in the degree to which or manner in which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002081 ;
    owl:annotatedTarget "Animals exhibit an increase in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002082 ;
    owl:annotatedTarget "Animals exhibit a decrease in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037960", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002083 ;
    owl:annotatedTarget "The frequency and distribution of crossover events differs from that observed for controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037960", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002084 ;
    owl:annotatedTarget "Animals differ from controls in respect to the frequency of expected double crossover events observed." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037960", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002085 ;
    owl:annotatedTarget "The number of crossover events differs from that of observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037960", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002086 ;
    owl:annotatedTarget "The location-specific frequency of crossover events differs from that of observed in control animals, while the total number of crossover events does not significantly differ." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00039977", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002087 ;
    owl:annotatedTarget "Animals respond to hydrogen sulfide at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002088 ;
    owl:annotatedTarget "Animals respond to dauer pheromone at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002089 ;
    owl:annotatedTarget "Any variation in the form or composition of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002090 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as endosomes,  that traffic material between the plasma membrane and internal compartments of the cell, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002091 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as late endosomes,  that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002092 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as early endosomes,  that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002093 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes,  that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002094 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002095 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002096 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000173 ;
    owl:annotatedTarget "The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002097 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002098 ;
    owl:annotatedTarget "Any variation in the subcellular localization of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002099 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002100 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as endosomes,  that traffic material between the plasma membrane and internal compartments of the cell, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002101 ;
    owl:annotatedTarget "Any variation in the subcellular localization of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that exists in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002102 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002103 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002104 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes,  that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002105 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as late endosomes,  that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002106 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as early endosomes,  that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002107 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002108 ;
    owl:annotatedTarget "Any variation in the form or composition of specialized cell types, compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002109 ;
    owl:annotatedTarget "Animals are affected by exposure to the drug." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002110 ;
    owl:annotatedTarget "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041129", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002111 ;
    owl:annotatedTarget "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037960", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002112 ;
    owl:annotatedTarget "Animals are unable to maintain paired chromosome throughout pachytene." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037960", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002113 ;
    owl:annotatedTarget "Animals differ from controls in respect to the formation of paired chromosome loci." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038270", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002114 ;
    owl:annotatedTarget "Animals become paralyzed after a measured amount of time swimming. In C. elegans, more then 80 percent of wild-type animals continue swimming vigorously in liquid even after 30 minutes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002115 ;
    owl:annotatedTarget "Animals do not avoid, and perhaps seek, environments that result in their death. In the case of C. elegans, this behavior is exemplified by animals that tend to crawl off the plate." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002116 ;
    owl:annotatedTarget "Animals are barely alive, but not entirely dead." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002117 ;
    owl:annotatedTarget "Animals exhibit constrictions in the anterior portion of the head that result in decapitation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040316", "WB:WBPaper00040815", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002118 ;
    owl:annotatedTarget "Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations.  In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1686", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002119 ;
    owl:annotatedTarget "The process of generating multiple mRNA molecules from differential use of exons in a primary transcript(s) does not occur or occurs with outcomes not observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0043504", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002120 ;
    owl:annotatedTarget "Any variation in the process of restoring mitochondrial DNA after damage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040387", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002121 ;
    owl:annotatedTarget "The presence of a mixture of more than one type of an organellar genome (mitochondrial DNA (mtDNA) or plastid DNA) within a cell or individual." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040387", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002122 ;
    owl:annotatedTarget "Mitochondria from spermatazoa persist in the developing embryo and animal as a result of bypassing the degradation mechanism that normally destroys paternal mitochondria immediately after fertilization. This can often lead to a form of heteroplasmy." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040843", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002123 ;
    owl:annotatedTarget "The pattern or state of acetylation modifications of histones varies from that of controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006290", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002124 ;
    owl:annotatedTarget "The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040519", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002125 ;
    owl:annotatedTarget "Animals do not grow fast or the quality of growth is decreased when exposed to a specific chemical compound when compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002126 ;
    owl:annotatedTarget "Animals exhibit a decrease in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038442", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002127 ;
    owl:annotatedTarget "Animals exhibit variation rate of directed movement of organelles or molecules along microtubules in nerve cell axons, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041718", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002128 ;
    owl:annotatedTarget "Males remain on food in the absence of mates, a defect in male mate-searching behavior observed in control males." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032112", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002129 ;
    owl:annotatedTarget "Relative levels of mtDNA differ from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041718", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002130 ;
    owl:annotatedTarget "Males exhibit variations of the behaviors observed in control animals that follow the completion of mating." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002131 ;
    owl:annotatedTarget "Animals display variations in the structure or organization of the components of the muscle, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038066", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002132 ;
    owl:annotatedTarget "The formation, organization, or stability of a protein complex is altered in comparison to corresponding complexes in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002133 ;
    owl:annotatedTarget "The bulk flow of cytoplasm in the egg, that facilitates mixing of ooplasm, occurs at a reduced rate compared to that measured for controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00039982", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002134 ;
    owl:annotatedTarget "Animals are less successful than controls in evading predators during predator-prey interactions." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00039982", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002135 ;
    owl:annotatedTarget "Predator-prey interactions differ from that observed in control interactions." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003577", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002136 ;
    owl:annotatedTarget "Animals are missing the anchor cell. In C. elegans the anchor cell is a key organizer of vulval patterning and morphogenesis." .

[]
    oboInOwl:hasDbXref "GO:0006413", "WB:WBPaper00039835", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002137 ;
    owl:annotatedTarget "The rate of the process preceding formation of the peptide bond between the first two amino acids of a protein is reduced. This process includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.  Increase in free ribosomes (monosomes) are indicative of reduced translation initiation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040849", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002138 ;
    owl:annotatedTarget "Animals are altered in their capacity to survive a normally lethal temperature treatment as a consequence of pretreatment at an elevated but sublethal temperature." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035457", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002139 ;
    owl:annotatedTarget "Any variation in the morphological appearance of the linker cell compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032050", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002140 ;
    owl:annotatedTarget "Males do not respond to small molecules or compounds that have been shown to attract control males. This phenotype is often measured by an increase in reversal frequency or time spent in a specified scoring region" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00042217", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002141 ;
    owl:annotatedTarget "Variations in the process of gaseous oxygen intake between an organism and its environment compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0005746", "WB:WBPaper00042217", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002142 ;
    owl:annotatedTarget "The activity, composition, or organization of the complexes of the electron transport chain, embedded in the inner mitochondrial membrane, differ from controls." .

[]
    oboInOwl:hasDbXref "GO:0045273", "WB:WBPaper00042217", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002143 ;
    owl:annotatedTarget "The part of the respiratory chain that catalyzes the oxidation of succinate and connects the TCA cycle with the respiratory chain, differs in activity, composition, or organization, from that of controls." .

[]
    oboInOwl:hasDbXref "GO:0005747", "WB:WBPaper00042217", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002144 ;
    owl:annotatedTarget "The protein complex located in the mitochondrial inner membrane that is the first entry point for electrons into the electron transport chain and catalyzes proton translocation coupled to the oxidation of NADH by ubiquinone, differs in activity, composition, or organization from that of controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027057", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002145 ;
    owl:annotatedTarget "Animals are unable to produce or maintain short interfering RNA (siRNA) from double stranded RNA (dsRNA). siRNAs are required to initiate interference of gene expression." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027057", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002146 ;
    owl:annotatedTarget "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in the germline. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027057", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002147 ;
    owl:annotatedTarget "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in somatic cells. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027057", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002148 ;
    owl:annotatedTarget "Animals show reduced susceptibility to gene silencing in somatic cells triggered by double stranded RNA (dsRNA), compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027057", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002149 ;
    owl:annotatedTarget "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of the small X-chromosome derived RNAs (X cluster) species of small RNA." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027057", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002150 ;
    owl:annotatedTarget "RNAi silencing mechanisms triggered by exogenously introduced (foreign) dsRNA, do not work to the same degree as in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037823", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002151 ;
    owl:annotatedTarget "Animals exhibit variations in the extent to which polyadenylated mRNA transcripts become deadenylated" .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002152 ;
    owl:annotatedTarget "Programmed cell death of germ cells caused by exposure to physical or chemical DNA-damaging agents does not occur to the same extent as it does in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029211", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002153 ;
    owl:annotatedTarget "The production of silencing RNA from dsRNA is significantly deficient compared to controls. Deficiencies in this process can result in a defective RNAi response compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032489", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002154 ;
    owl:annotatedTarget "The extent of mRNA ribosome associations varies from controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029211", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002155 ;
    owl:annotatedTarget "The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031647", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002156 ;
    owl:annotatedTarget "Wild-type animals will exhibit an altered temperature preference based on food/temperature conditioning. Temperature learning variants do not exhibit altered responses to temperature after conditioning compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032489", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002157 ;
    owl:annotatedTarget "The extent of translational repression varies from controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044350", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002158 ;
    owl:annotatedTarget "The selective elimination of P granule components and subsequent aggregation of degraded components into PGL granules is disrupted." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032276", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002159 ;
    owl:annotatedTarget "Animals exhibit an increase in pathogen accumulation, persistent colonization, and luminal distension of the intestine." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00042072", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002160 ;
    owl:annotatedTarget "The intracellular complex of proteins that participates in bidirectional transport of molecules (cargo) along axonemal microtubules is not made up of or does not maintain the proper number or ratio of components as found in control animals." .

[]
    oboInOwl:hasDbXref "GO:0006338", "WB:WBPaper00040620", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002161 ;
    owl:annotatedTarget "Animals exhibit variations from controls in the organization of chromatin, including in relation to associated complexes, that occur during the mitotic cell division cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038412", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002162 ;
    owl:annotatedTarget "Cells exhibit mitotic spindles with more than two poles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036073", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002163 ;
    owl:annotatedTarget "Animals exhibit a decreased rate of oxygen utilization compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0045087", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002164 ;
    owl:annotatedTarget "Animals exhibit variations in their defense responses that are mediated by germline encoded components that directly recognize components of potential pathogens." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038066", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002165 ;
    owl:annotatedTarget "The extent or other quality of the excitatory postsynaptic potential (EPSP) induced by in vitro stimuli differs from that of controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00039987", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002166 ;
    owl:annotatedTarget "The difference in electrical potential between the interior and the exterior of the muscle cell either in the resting state or during evoked stimulation differs from controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045092", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002167 ;
    owl:annotatedTarget "The amount of histone methylation, for example as measured by the amount of H3K4me2, increases over successive generations" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045092", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002168 ;
    owl:annotatedTarget "Animals exhibit a decline in fertility over generations. This is often assessed by counting laid eggs over successive generations." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027157", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002169 ;
    owl:annotatedTarget "Animals stop producing progeny significantly before the time reproduction stops in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002170 ;
    owl:annotatedTarget "Any variation in the series of molecular signals in which a cell or tissue uses calcium ions to convert a signal into a response, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0036176", "WB:WBPaper00042397", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002171 ;
    owl:annotatedTarget "Animals exhibit variations in the characteristic movement towards typically attractive alkaline pH (pH higher than 7) compared to control. However animals tend to avoid very high pH levels (pH11).  pH is a measure of the acidity or basicity of an aqueous solution. In C. elegans animals chemotax toward higher alkaline pH." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040246", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002172 ;
    owl:annotatedTarget "Infected animals exhibit variations in the process of releasing pathogens back into the environment, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032029", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002173 ;
    owl:annotatedTarget "Animals exhibit variations in the number of cells that make up the organism compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032029", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002174 ;
    owl:annotatedTarget "The number of cells in the organism is reduced compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032029", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002175 ;
    owl:annotatedTarget "The number of cells in the organism is increased compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032029", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002176 ;
    owl:annotatedTarget "Animals exhibit variations in the structure, organization or placement of the population of the lateral, alae-producing epithelial cells (seam cells), compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0005886", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002177 ;
    owl:annotatedTarget "Any variation in the components that make up the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control." .

[]
    oboInOwl:hasDbXref "GO:0009897", "GO:0009898", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002178 ;
    owl:annotatedTarget "Any variation in the components that make up either of the two leaflets of the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004952", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002179 ;
    owl:annotatedTarget "Animals do not arrest mitotic germ cell division, as control animals, when treated with X-ray radiation." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041303", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002180 ;
    owl:annotatedTarget "Animals exhibit variations in the process by which cells having undergone programmed cell death are shed or extruded into the extracellular environment." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041303", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002181 ;
    owl:annotatedTarget "Animals produce an excess number of excretory cells compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00042351", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002182 ;
    owl:annotatedTarget "Animals exhibit variations in endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000174 ;
    owl:annotatedTarget "Any variation in the progression of the layer of connective tissue over the surface of tissues that serves to separate it from neighboring tissues, from its formation to its mature structure compared to control (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00042351", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002183 ;
    owl:annotatedTarget "Animals exhibit variations in levels of DNA damage caused by oxidative stress." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044006", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002184 ;
    owl:annotatedTarget "Any variation in the amount of cells undergoing apoptosis in organism as a result of deprivation of nourishment, compared to control. In C. elegans, starvation normally causes increased apoptosis." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003645", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002185 ;
    owl:annotatedTarget "Animals develop endodermal cells/tissue from precursor cells that do not normally produce endodermal cells/tissue." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003645", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002186 ;
    owl:annotatedTarget "Animals develop pharyngeal muscles from precursor cells that do not normally produce pharyngeal muscles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003574", "WB:WBPaper00003645", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002187 ;
    owl:annotatedTarget "Animals develop body wall muscle from precursor cells that do not normally produce body wall muscle." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002188 ;
    owl:annotatedTarget "Any variation in the progression of the components of the male gonad that are separate from the germline proper over time, from its formation to its mature structure compared to control.  In C. elegans, the male somatic gonad consists of three tissues: distal tip cells (DTCs), the seminal vesicle, and the vas deferens (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005116", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002189 ;
    owl:annotatedTarget "Animals produce an excess number of linker cells compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002190 ;
    owl:annotatedTarget "The population of hypodermal cells is reduced compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033137", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002191 ;
    owl:annotatedTarget "Animals produce a reduced number of sex myoblasts compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033137", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002192 ;
    owl:annotatedTarget "Animals produce an excess number of sex myoblasts compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson363" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000175 ;
    owl:annotatedTarget "Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044058", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002193 ;
    owl:annotatedTarget "The orientation of the progeny of P7.p mimic those of P5.p and face towards the posterior of the worm, a phenotype referred to as posterior-reversed vulval lineage (P-Rvl)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038311", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002194 ;
    owl:annotatedTarget "Animals do not differ in size when grown on different food sources to the same extent as that measured for control animals. For example, in C. elegans, wild type worms are 1.65 times larger when grown on HB101 compared to those grown on OP50." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038311", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002195 ;
    owl:annotatedTarget "Animals exhibit variations in growth rate or the outcome of growth in response to food compared to control. In C. elegans, animals exhibit an increase or decrease in growth rate depending on the type of bacteria they are fed." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036046", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002196 ;
    owl:annotatedTarget "The driving force of the outward flow of ions does not exceed the inward flow for the opposite driving force or is otherwise altered when compared to that measured for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002197 ;
    owl:annotatedTarget "Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded is altered from that observed for controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038066", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002198 ;
    owl:annotatedTarget "The proper localization and assembly of components at the junction of a neuron with a muscle cell varies from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00039855", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002199 ;
    owl:annotatedTarget "The degree of stimulus-evoked calcium concentration changes differs from that of controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002200 ;
    owl:annotatedTarget "Variations in the progression of the muscles of the adult hermaphrodite oviduct over time from their initial formation to their mature structure compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005978", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002201 ;
    owl:annotatedTarget "Dying animals cells exhibit defects in the fragmentation of chromosomal DNA into oligonucleosomal-length fragments compared to control animals. This process can be monitored by the quantity and quality of TUNEL (TdT-mediated dUTP nick end labeling)-positive nuclei." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005085", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002202 ;
    owl:annotatedTarget "Embryos exhibit defects in the extension of pharyngeal cells toward the buccal opening during embryogenesis compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000176 ;
    owl:annotatedTarget "Any variation in the specific actions or reactions of an animal after completion of feeding, typically after a fast, compared to that observed in control animals. In C. elegans worms become behaviorally quiescent and cease feeding and moving when sated." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004688", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002203 ;
    owl:annotatedTarget "Corpses resulting from programmed cell death appear different in size or shape from those of corpses in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005996", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002204 ;
    owl:annotatedTarget "Animals exhibit defects in the muscle contractions of the anterior region of corpus, the area responsible for allowing food to enter the corpus." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024452", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000177 ;
    owl:annotatedTarget "Any variation that results in a decrease of acetylcholine esterase levels, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045849", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002205 ;
    owl:annotatedTarget "Animals exhibit negative effects on growth, development, or metabolism when exposed to a galactose-rich diet, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045849", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002206 ;
    owl:annotatedTarget "Animals process dietary galactose differently than control animals, these differences can result in increased and or decreased levels of intermediary galactose metabolites." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003453", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002207 ;
    owl:annotatedTarget "Animals are missing one or both gonad arms, the normally U-shaped projections of the gonad that extend into the anterior or posterior of the animal and bends back towards the center of the animal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003383", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002208 ;
    owl:annotatedTarget "The expression of a protein, as determined by antibody staining, varied from controls with respect to timing such that the protein was observed to be expressed at earlier timepoints or later timepoints than controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003428", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002209 ;
    owl:annotatedTarget "Any variation in the development of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003428", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002210 ;
    owl:annotatedTarget "Animals exhibit an extra number of the finger-like sensory sensilla that project from the tail and embed in the male fan." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003450", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002211 ;
    owl:annotatedTarget "Animals exhibit defects in dye-filling of the neuronal cells of the phasmid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002212 ;
    owl:annotatedTarget "Animals exhibit defects in dye-filling of the neuronal cells of the amphid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003656", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002213 ;
    owl:annotatedTarget "Any variation that results in a decrease in the catalytic phosphorylation activity of a kinase enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component). Kinases are enzymes capable of phosphorylating their respective substrates." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003574", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002214 ;
    owl:annotatedTarget "Animals contain an excess number of pharyngeal muscle cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003574", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002215 ;
    owl:annotatedTarget "Any variation that results in a fewer than control number of body wall muscle cells." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003574", "WB:WBPaper00003656", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002216 ;
    owl:annotatedTarget "Any variation in the cellular or subcellular distribution of a gene product, as detected by antibody staining, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002619", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002217 ;
    owl:annotatedTarget "Animals respond to antimony at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002619", "WB:WBPaper00029261", "WB:WBPaper00031023", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002218 ;
    owl:annotatedTarget "Animals respond to arsenite at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031850", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002219 ;
    owl:annotatedTarget "Animals respond to fluoranthene at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029261", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002220 ;
    owl:annotatedTarget "Animals respond to antimonite at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004381", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002221 ;
    owl:annotatedTarget "The pharynx contains cavities, possibly indicative of inappropriate cell death." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004381", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002222 ;
    owl:annotatedTarget "The uterus contains cavities, possibly indicative of inappropriate cell death." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044740", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002223 ;
    owl:annotatedTarget "Animals respond at a faster rate or to lower concentrations of manganese that that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000178 ;
    owl:annotatedTarget "Cells are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004381", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002224 ;
    owl:annotatedTarget "Animals respond to mercury at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004381", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002225 ;
    owl:annotatedTarget "Animals respond to lead at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005255", "WB:WBPaper00006388", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002226 ;
    owl:annotatedTarget "Animals respond to cobalt at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029261", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002227 ;
    owl:annotatedTarget "Animals exhibit variations in their response to lead compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029261", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002228 ;
    owl:annotatedTarget "Animals exhibit variations in their response to aluminum compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029261", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002229 ;
    owl:annotatedTarget "Animals exhibit variations in their response to chromium compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044740", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002230 ;
    owl:annotatedTarget "Animals exhibited higher amounts of internal metal concentrations compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044740", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002231 ;
    owl:annotatedTarget "Oxidative stress induced by manganese differs from that of control worms." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005543", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002232 ;
    owl:annotatedTarget "The polarity reversal process by which synaptic components are removed from one side of the synapse and then reformed on the opposite cell does not occur or occurs in a different manner than in controls. In C. elegans, at the end of the L1 stage, the DD neurons undergo a complete polarity reversal such that the ventral synapses disappear and new synapses are formed on opposing dorsal body muscles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041219", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002233 ;
    owl:annotatedTarget "The swimming behavior of animals are influenced or modulate by the osmolarity of the swimming buffer. The swimming of wild-type C. elegans animals are not affected by the osmolarity of the swimming liquid." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005190", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002234 ;
    owl:annotatedTarget "Animals contain excess acidified intracellular compartments. These compartments are positive for indicators such as Acridine Orange as well as LysoTracker Red, in a lysosome-like manner." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002235 ;
    owl:annotatedTarget "Animals are unable to grow on media depleted of phosphate." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037899", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002236 ;
    owl:annotatedTarget "The degradation of endocytosed and intracellular material does not occur to the same extent as it does in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037899", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002237 ;
    owl:annotatedTarget "Animals exhibit disruptions in tubular or tubulo-vesicular structures that function in endocytic transport from early to recycling endosomes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040454", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002238 ;
    owl:annotatedTarget "Animals exhibit increased endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040454", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002239 ;
    owl:annotatedTarget "Animals exhibit reduced endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040622", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002240 ;
    owl:annotatedTarget "Any variation in the morphology of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036303", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002241 ;
    owl:annotatedTarget "Animals consume less food than control animals" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040550", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002242 ;
    owl:annotatedTarget "Animals exhibit detrimental responses to iron deficiency more readily than control animals." .

[]
    oboInOwl:hasDbXref "GO:0046938", "WB:WBPaper00036020", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002243 ;
    owl:annotatedTarget "Animals do not produce the same amount of functional phytochelatins as measured in control worms. Phytochelatins are any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712", "WB:WBperson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000179 ;
    owl:annotatedTarget "Cells specialized for receiving, conducting and transmitting impulses in the nervous system are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036020", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002244 ;
    owl:annotatedTarget "Animals respond to arsenic at a lower concentration or at a shorter exposure time compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040622", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002245 ;
    owl:annotatedTarget "Animals exhibit reduced levels of endogenous zinc compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040622", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002246 ;
    owl:annotatedTarget "Animals exhibit increased levels of endogenous zinc compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040622", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002247 ;
    owl:annotatedTarget "Variations in the regulation of levels, transport, and metabolism of copper ions within an organism compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040622", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002248 ;
    owl:annotatedTarget "Animals exhibit detrimental responses to zinc deficiency more readily than control animals" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040914", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002249 ;
    owl:annotatedTarget "Protein oxidation levels, as measured by carbonylated protein levels for example, are reduced compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002250 ;
    owl:annotatedTarget "Animals respond to silver at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044630", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002251 ;
    owl:annotatedTarget "Animals respond to silver nanoparticles (AgNPs) at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046393", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002252 ;
    owl:annotatedTarget "Animals are more prone to infection by virus compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046393", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002253 ;
    owl:annotatedTarget "Animals exhibit lowered levels of any or all of the clades of 22G RNA molecules, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046393", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002254 ;
    owl:annotatedTarget "Three-prime (3') uridylation of mRNA targeted for silencing does not occur at the same rate or extent of targeted mRNA in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038278", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002255 ;
    owl:annotatedTarget "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of amino acids within the organism or cell compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038278", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002256 ;
    owl:annotatedTarget "Animals exhibit variations in their response to selenium compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038278", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002257 ;
    owl:annotatedTarget "Animals respond to iron at a lower concentration or a shorter exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038278", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002258 ;
    owl:annotatedTarget "Animals fail to exhibit toxicity to the concentration of nickel that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to nickel include delayed development or lethality." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046432", "WB:WBPerson557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002259 ;
    owl:annotatedTarget "The number of terminal regions of a neuron's dendrite is less that that observed for control animals." .

[]
    oboInOwl:hasDbXref "GO:0030424", "WB:WBPaper00005236", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000180 ;
    owl:annotatedTarget "Animals display variations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041364", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002260 ;
    owl:annotatedTarget "Ooctyes and or sperm appear vacuolated and degenerated compared to gametes in control animals. This degeneration is not due to normal programmed cell death." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00042557", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002261 ;
    owl:annotatedTarget "An effective connection between reciprocal target neurons is not established properly." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005543", "WB:WBPaper00038066", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002262 ;
    owl:annotatedTarget "Animals display variations in the distribution of the constituents of the postsynaptic side of the active zone, compared to control animals, that are required for receiving signals from the presynaptic side." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040353", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002263 ;
    owl:annotatedTarget "Any increase in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036073", "WB:WBPaper00040353", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002264 ;
    owl:annotatedTarget "Animals exhibit an increase in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041842", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002265 ;
    owl:annotatedTarget "Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035277", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002266 ;
    owl:annotatedTarget "Animals exhibit variations in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035277", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002267 ;
    owl:annotatedTarget "Animals exhibit increases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035277", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002268 ;
    owl:annotatedTarget "Animals exhibit decreases in the overall amount of mitochondria present in the animal, as determined by, for example, Mitotracker staining." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035277", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002269 ;
    owl:annotatedTarget "Animals exhibit an increased rate of oxygen utilization compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040386", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002270 ;
    owl:annotatedTarget "Animals exhibit a decrease in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032310", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002271 ;
    owl:annotatedTarget "Animals exhibit variations in the rate at which food is absorbed by the intestine, as determined by a time-course recording of fat staining (by C1-BODIPY-C12, for example) normalized to controls" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006515" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002272 ;
    owl:annotatedTarget "Animals exhibit variations in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045849", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002273 ;
    owl:annotatedTarget "Animals exhibit enhanced negative effects on growth, health, development or metabolism, in response to dietary sugar-rich diets, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson22615", "WB:WBPerson7165" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002274 ;
    owl:annotatedTarget "Males receive copulatory plugs from other males, deposited elsewhere on their bodies, in the absence of any orifice. This typically involves penetration of the depositing male's spicules directly through the cuticle of the recipient male." .

[]
    oboInOwl:hasDbXref "WB:WBPerson22615", "WB:WBPerson7165" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002275 ;
    owl:annotatedTarget "Males receive copulatory plugs from other males, deposited on their excretory pores. This phenotype is polymorphic among C. elegans strains and also in C. briggsae." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032396", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002276 ;
    owl:annotatedTarget "The life span of dauer-staged animals is shorter than that observed in control dauer animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032396", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002277 ;
    owl:annotatedTarget "The life span of dauer-staged animals is longer than that observed in control dauer animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046494", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002278 ;
    owl:annotatedTarget "Animals do not develop acute functional tolerance to alcohol after a short exposure, unlike that observed in control animals" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00042257", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002279 ;
    owl:annotatedTarget "Animals exhibit a decrease in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032396", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002280 ;
    owl:annotatedTarget "Animals exhibit resistance to osmotic stress compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032396", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002281 ;
    owl:annotatedTarget "Animals exhibit hypersensitivty to osmotic stress compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026641", "WB:WBPaper00038332", "WB:WBPaper00041372", "WB:WBPaper00043981", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002282 ;
    owl:annotatedTarget "Animals exhibit increased levels of the process by which their cells digest parts of their own cytoplasm, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006070", "WB:WBPaper00035076", "WB:WBPaper00041851", "WB:WBPaper00043981", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002283 ;
    owl:annotatedTarget "Animals exhibit reduced levels of the process by which their cells digest parts of their own cytoplasm, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002284 ;
    owl:annotatedTarget "Any variation in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002285 ;
    owl:annotatedTarget "Animals exhibit a decrease in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002286 ;
    owl:annotatedTarget "Animals exhibit an increase in the extent of the maximum flex of the most anterior portion of the animal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002287 ;
    owl:annotatedTarget "The most posterior portion of the animal exhibits variations in its movement compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002288 ;
    owl:annotatedTarget "Any variation in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002289 ;
    owl:annotatedTarget "Animals exhibit an increase in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002290 ;
    owl:annotatedTarget "Animals exhibit a decrease in the extent of the maximum flex of the most posterior portion of the animal compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002291 ;
    owl:annotatedTarget "Animals exhibit variations in body posture with regard to the extent of displacement measured from the mean position to an extreme position compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002292 ;
    owl:annotatedTarget "Animals exhibit variations in body posture caused by a decrease in the extent of displacement measured from the mean position to an extreme position compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002293 ;
    owl:annotatedTarget "Animals exhibit variations in body posture caused by an increase in the extent of displacement measured from the mean position to an extreme position compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002294 ;
    owl:annotatedTarget "Animals exhibit variations in body posture with regard to the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002295 ;
    owl:annotatedTarget "Animals exhibit variations in body posture caused by a decrease in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002296 ;
    owl:annotatedTarget "Animals exhibit variations in body posture caused by an increase in the distance between repeating units of a wave pattern compared to control animals. In C. elegans, characteristic sinusoidal body posture is sinusoidal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002297 ;
    owl:annotatedTarget "Animals exhibit variations in the occurrence of a coil-like body posture compared to control animals. This includes the amount of time spent in a coil, the frequency with which coils form and the inappropriate formation of a coil, for example when attempting to locomote." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002298 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of time spent with its body posture in a coil or the frequency with which they form coils compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002299 ;
    owl:annotatedTarget "Animals spend less time with their body posture in a coil or they decrease the frequency with which they form coils compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002300 ;
    owl:annotatedTarget "Animals spend more time with their body posture in a coil or they increase the frequency with which they form coils compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002301 ;
    owl:annotatedTarget "The extreme anterior of the animal exhibits variations in its movement compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002302 ;
    owl:annotatedTarget "Animals exhibit a decrease in the movement of the extreme anterior portion of the body to a new location compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002303 ;
    owl:annotatedTarget "Animals exhibit an increase in the movement of the extreme anterior portion of the body to a new location compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002304 ;
    owl:annotatedTarget "Animals exhibit a decrease in the movement of the most anterior portion of the body to a new location compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002305 ;
    owl:annotatedTarget "Animals exhibit an increase in the movement of the most anterior portion of the body to a new location compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00001105", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000181 ;
    owl:annotatedTarget "Animals display variations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002306 ;
    owl:annotatedTarget "Animals exhibit a decrease in the movement of the most posterior portion of the body to a new location compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002307 ;
    owl:annotatedTarget "Animals exhibit an increase in the movement of the most posterior portion of the body to a new location compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002308 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002309 ;
    owl:annotatedTarget "Animals exhibit a decrease in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002310 ;
    owl:annotatedTarget "Animals exhibit an increase in the amount of time spent in a paused state, which is neither moving forward or backward, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002311 ;
    owl:annotatedTarget "Variations in the behavior by which an organism alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002312 ;
    owl:annotatedTarget "Animals exhibit variations in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002313 ;
    owl:annotatedTarget "Animals exhibit an increase in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002314 ;
    owl:annotatedTarget "Animals exhibit a decrease in the frequency of execution of the behavior by which the animal alters its trajectory of movement compared to control, excluding shifts from forward to backward movements (this is reversal)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002315 ;
    owl:annotatedTarget "Animals exhibit variations in their movement at high-speed in the forward direction with brief backward movement compared to control. During roaming, control animals often traverse wide regions." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002316 ;
    owl:annotatedTarget "Animals exhibit variations in the low-speed/high turning movement that restricts them to a confined region compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002317 ;
    owl:annotatedTarget "Animals exhibit an increase in the low-speed/high turning movement that usually restricts them to a confined region compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002318 ;
    owl:annotatedTarget "Animals exhibit a decrease in the low-speed/high turning movement that usually restricts them to a confined region compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002319 ;
    owl:annotatedTarget "Animals exhibit an increase in their high-speed movement in the forward direction with brief backward movement compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002320 ;
    owl:annotatedTarget "Variations in the behavior by which an organism shifts from forward to backward movements." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002321 ;
    owl:annotatedTarget "Animals exhibit decreased velocity of forward translocation of any point along the animal's track from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002322 ;
    owl:annotatedTarget "Animals exhibit increased velocity of forward translocation of any point along the animal's track from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002323 ;
    owl:annotatedTarget "Animals exhibit variations in the velocity of backward translocation of any point along the animal's track from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002324 ;
    owl:annotatedTarget "Animals exhibit decreased velocity of backward translocation of any point along the animal's track from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002325 ;
    owl:annotatedTarget "Animals exhibit increased velocity of backward translocation of any point along the animal's track from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002326 ;
    owl:annotatedTarget "Animals exhibit a decrease in the net velocity of an animal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002327 ;
    owl:annotatedTarget "Animals exhibit an increase in the net velocity of an animal" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002328 ;
    owl:annotatedTarget "Animals exhibit an increase in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002329 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002330 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002331 ;
    owl:annotatedTarget "OBSOLETE." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002332 ;
    owl:annotatedTarget "Animals exhibit variations in the length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002333 ;
    owl:annotatedTarget "Animals exhibit increased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002334 ;
    owl:annotatedTarget "Animals exhibit decreased length of the minimum enclosing rectangle surrounding the worm body on a solid medium, as viewed through the microscope." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002335 ;
    owl:annotatedTarget "Animals exhibit variations in the extent to which the overall path of movement is curved, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002336 ;
    owl:annotatedTarget "Animals exhibit increases in the extent to which the overall path of movement is curved, producing tighter and more frequent curves compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002337 ;
    owl:annotatedTarget "Animals exhibit decreases in the extent to which the overall path of movement is curved, producing shallower, less frequent curves and an overall straighter path, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002338 ;
    owl:annotatedTarget "Animals exhibit variations in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002339 ;
    owl:annotatedTarget "Animals exhibit increases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002340 ;
    owl:annotatedTarget "Animals exhibit decreases in the body-area-to-length ratio and/or the width-to-length ratio, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002341 ;
    owl:annotatedTarget "Animals exhibit variations in instantaneous posture with regards to eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002342 ;
    owl:annotatedTarget "Animals exhibit increased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002343 ;
    owl:annotatedTarget "Animals exhibit decreased posture eccentricity (measure of circularity) or the mean number (and/or standard deviation) of instantaneous body bends." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002344 ;
    owl:annotatedTarget "Animals spend less time backing compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002345 ;
    owl:annotatedTarget "Variations in the spontaneous or induced forward crawling locomotion of an animal compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002346 ;
    owl:annotatedTarget "Animals spend more time in forward locomotion, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002347 ;
    owl:annotatedTarget "Animals spend less time in forward locomotion, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043908", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002348 ;
    owl:annotatedTarget "Animals exhibit an increase in the frequency of oscillations between adjacent body segments from that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044390", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002349 ;
    owl:annotatedTarget "The levels of phosphatidylinositol 3-phosphate (a.k.a. PtdIns3P or PI3P) are reduced compared to those of control animals" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041478", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002350 ;
    owl:annotatedTarget "Animals exhibit increases in steady-state levels of hydrogen peroxide (H2O2) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041478", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002351 ;
    owl:annotatedTarget "Animals exhibit reductions in steady-state levels of hydrogen peroxide (H2O2) compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046188", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002352 ;
    owl:annotatedTarget "Animals exhibit elevated levels of transfer RNA compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046188", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002353 ;
    owl:annotatedTarget "Animals exhibit reduced levels of transfer RNA compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045575", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002354 ;
    owl:annotatedTarget "Animals are more prone to infection from fungal pathogens compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045575", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002355 ;
    owl:annotatedTarget "Animals are more prone to infection by bacterial pathogens compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045575", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002356 ;
    owl:annotatedTarget "Animals are negatively affected by bacteria that is nonpathogenic to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045546", "WB:WBPaper00045575", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002357 ;
    owl:annotatedTarget "Animals exhibit an increase in the quantity of metabolites, small molecule products or intermediates required for the metabolic functioning of the cell or organism." .

[]
    oboInOwl:hasDbXref "GO:0043065", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000182 ;
    owl:annotatedTarget "Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037659", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002358 ;
    owl:annotatedTarget "The conversion of one differentiated cell type into another does not occur as it does in control animals. In C. elegans, the Y cell undergoes a dramatic redifferentiation from being a cell in of the rectum to a PDA neuron. This transdifferentiation requires the cell to withdraw from its established position, migrate, and then become a motor neuron." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041478", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002359 ;
    owl:annotatedTarget "Animals exhibit an increase in the covalent modification of one or more native amino acid side chains in proteins to carbonyl derivatives such as an aldehyde or ketone." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046830", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002360 ;
    owl:annotatedTarget "Animals respond more severely to cold than control animals subjected to the same cold conditions." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046830", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002361 ;
    owl:annotatedTarget "Animals exhibit increased fluidity of cell membranes, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048594", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002362 ;
    owl:annotatedTarget "Variations in the process by which one or more SUMO moieties are added to a protein, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024451", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002363 ;
    owl:annotatedTarget "Animals are more resistant to the reduction of cholesterol in the environment compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024451", "WB:WBPerson2987", "WB:WBPerson9270" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002364 ;
    owl:annotatedTarget "Spontaneous axon breaks leading to degeneration of separated segments." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046306", "WB:WBPerson29819", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002365 ;
    owl:annotatedTarget "Following axon damage, animals do not undergo axonal fusion after reconnection between the regrowing axon and its separated segment to the same extent as observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00039982", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002366 ;
    owl:annotatedTarget "Animals do not suppress exploratory head movements in response to anterior touch stimuli, unlike control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00039982", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002367 ;
    owl:annotatedTarget "Animals are less successful than controls in extracting themselves from mesh or other non-living obstructing obstacles." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005190", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002368 ;
    owl:annotatedTarget "Lysosomal refractile bodies are apoptotic-like cell corpse; however, they differ in size and shape and can be described as resembling irregular cell corpses. These bodies have been shown to represent enlarged lysosomes and can occur in conjunction with altered programmed cell death programs." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046953", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002369 ;
    owl:annotatedTarget "Animals exhibit sister cells that have lost otherwise normal asynchrony of cell division timing, compared to control animals. This results in sister cells aberrantly dividing in synchrony." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046106", "WB:WBPerson12691", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002370 ;
    owl:annotatedTarget "Animals fail to execute their characteristic movements to avoid noxious heat in a manner consistent with controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004275", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002371 ;
    owl:annotatedTarget "Vesicles, including those in cells, cell bodies, or synaptic terminals, do not properly form or maintain an intermediate state, such as remain coated with a clathrin coat." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004275", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002372 ;
    owl:annotatedTarget "Vesicles in the presynaptic terminal differ in size, shape, or composition from those observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048410", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002373 ;
    owl:annotatedTarget "Animals show a stronger preference for a particular bacterium that has been grown under conditions that differ from a control lawn." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041467", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002374 ;
    owl:annotatedTarget "Animals are deficient in the transport of silencing RNAs between cells during the systemic RNAi response process." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041219", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002375 ;
    owl:annotatedTarget "Animals that exhibit paralysis (reduced thrashing) revert back to normal swimming behavior that can be tabulated as a reversion index (number revertants/number paralysis) and reversion probability (time in reversion/time after paralysis)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046960", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002376 ;
    owl:annotatedTarget "Animals exhibit one or more mRNAs with decreased length of the 3' polyadenine tail, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046960", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002377 ;
    owl:annotatedTarget "Animals exhibit one or more mRNAs with increased length of the 3' polyadenine tail, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048530", "WB:WBPerson495", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002378 ;
    owl:annotatedTarget "Variations in the characteristic movement away from specific disease causing agents (pathogens) compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045008", "WB:WBPerson298", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002379 ;
    owl:annotatedTarget "The subcellular localization of mitochondrial organelles differ from that observed in control cells." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045008", "WB:WBPerson298", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002380 ;
    owl:annotatedTarget "Neurons undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles at a faster rate or greater extent than those under conditions that elicit this response in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046134", "WB:WBPerson14245", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002381 ;
    owl:annotatedTarget "Animals exhibit variations in the amount and/or quality of pheromone produced compared to control animals at a defined stage." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045930", "WB:WBPerson12526", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002382 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of a bioactive compound that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals.  A bioactive compound is a chemical found in small amounts in organisms or, synthetically produced, that has effects on biological processes in another organism." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041335", "WB:WBPerson5092", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002383 ;
    owl:annotatedTarget "Any variation in the decreased behavioral response to repeated light head or tail touch compared to control. A gentle touch to the animal's head causes backward movement, whereas a gentle touch to the animal's tail causes forward movement. When wild-type animals are touched repeatedly on the head or tail, after some repetition they stop responding to the touch stimulus." .

[]
    oboInOwl:hasDbXref "WB:WBPerson512" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002384 ;
    owl:annotatedTarget "Animals are resistant to the toxicity of an anti-infective xenobiotic such as R24. Such small molecules protect the host from bacterial infection by inducing antibacterial immune responses via the p38 MAPK pathway. These molecules tend to have toxic effects in addition to immunostimulatory activity." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043891", "WB:WBPerson1928" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002385 ;
    owl:annotatedTarget "Animals fail to avoid a high pH (alkaline) environment as compared to control animals.  This is at very high pH, for example around pH11." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041071", "WB:WBPerson602" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002386 ;
    owl:annotatedTarget "Animals exhibit variations in the assembly of the fibrous body-membranous organelle (FB-MO), a nematode sperm-specific organelle involved in cytoplasmic partitioning during spermatogenesis, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041071", "WB:WBPerson602" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002387 ;
    owl:annotatedTarget "Dividing cells exhibit additional arrays of microtubules emanating from a spindle pole that do not connect to kinetochores, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000008", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002388 ;
    owl:annotatedTarget "Any variation in the second stage of cell division, between prophase and anaphase, during which the chromosomes become attached to the spindle fibers." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000008", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002389 ;
    owl:annotatedTarget "Any variation in the stage of meiotic or mitotic cell division in which the chromosomes move away from one another to opposite poles of the spindle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046953", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002390 ;
    owl:annotatedTarget "Animals exhibit larger variations in cell division timing events than in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041071", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002391 ;
    owl:annotatedTarget "Cells attempt to divide but fail to form two daughter cells." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048925", "WB:WBPerson2173" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002392 ;
    owl:annotatedTarget "A depletion of somatic, but not germline, lipid stores are observed near the end of the reproductive period." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041941", "WB:WBPerson1687", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002393 ;
    owl:annotatedTarget "Any variation in the processes that govern the directed extension of neurite projections along the anteroposterior  axis of the animal compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048406", "WB:WBPerson17560", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002394 ;
    owl:annotatedTarget "The closure of a phagosome does not occur and it remains connected with the plasma membrane, leaving the lumen open to the outside.  Complete closure usually occurs once an apoptotic cell has been surrounded by an engulfing cell." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048406", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002395 ;
    owl:annotatedTarget "Animals exhibit variations in recognition of cell corpses and initiation of corpse engulfment, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049105", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002396 ;
    owl:annotatedTarget "Animals with a tumorous germline exhibit a decreased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049105", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002397 ;
    owl:annotatedTarget "Animals with a tumorous germline exhibit an increased frequency of the presence of a tumor prolapse, a protrusion of tumor cells from the vulva, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046860", "WB:WBPerson14935" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002398 ;
    owl:annotatedTarget "Animals exhibit variations in the aggregation behavior of starved L1 larvae, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048522", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002399 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a specific neurotransmitter compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049467", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002400 ;
    owl:annotatedTarget "Animals do not live or live poorly in the presence of glucose concentrations that normally do not have an effect on control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049467", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002401 ;
    owl:annotatedTarget "The concentration of fatty acids in the animal are greater than that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002402 ;
    owl:annotatedTarget "A cell (or group of cells) is not found in the correct body position compared the placement in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040551", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002403 ;
    owl:annotatedTarget "Ventral midline blastomeres (P cells) are misaligned (not properly paired) along the ventral midline of larval animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040551", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002404 ;
    owl:annotatedTarget "Cell-cell contacts are abnormal, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040651", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002405 ;
    owl:annotatedTarget "Animals exhibit variations in the behavioral response to pheromones, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson1687", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002406 ;
    owl:annotatedTarget "Any neurite that is extended towards the posterior of the animal from neurons that in wild-type animals make only anterior projections (e.g. D-type neurons in C. elegans)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002407 ;
    owl:annotatedTarget "Any variation in the overall size of fertilized oocytes that are laid compared to those laid by control animals." .

[]
    oboInOwl:hasDbXref "GO:0000910", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002408 ;
    owl:annotatedTarget "Any variation that disrupts the cytoplasmic division of a cell during development compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002409 ;
    owl:annotatedTarget "One or more extra cleavage furrows are observed in a cell about to undergo division." .

[]
    oboInOwl:hasDbXref "GO:0032154", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002410 ;
    owl:annotatedTarget "Cells exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002411 ;
    owl:annotatedTarget "Cells exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002412 ;
    owl:annotatedTarget "Cells exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002413 ;
    owl:annotatedTarget "Animals have more than one nucleus in a particular cell type." .

[]
    oboInOwl:hasDbXref "GO:0005819", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002414 ;
    owl:annotatedTarget "Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart compared to control." .

[]
    oboInOwl:hasDbXref "GO:0051225", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002415 ;
    owl:annotatedTarget "Cells exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." .

[]
    oboInOwl:hasDbXref "GO:0043066", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000183 ;
    owl:annotatedTarget "Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0051653", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002416 ;
    owl:annotatedTarget "Any variation in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002417 ;
    owl:annotatedTarget "Any variation in the rotation of the spindle compared to control." .

[]
    oboInOwl:hasDbXref "GO:0005819", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002418 ;
    owl:annotatedTarget "Cells lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002419 ;
    owl:annotatedTarget "Any variation in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a cell cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036090", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002420 ;
    owl:annotatedTarget "Animals exhibit variations in the nature and/or extent of chromatin modification, including but not limited to acetylation and/or methylation of histones, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson10321", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002421 ;
    owl:annotatedTarget "Animals exhibit increased ability to survive at low temperatures compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036076", "WB:WBPaper00037064", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002422 ;
    owl:annotatedTarget "Animals respond to tunicamycin at a higher concentration or a longer exposure compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037064", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002423 ;
    owl:annotatedTarget "Animals exhibit variations in response to hypoxia, low oxygen conditions, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002424 ;
    owl:annotatedTarget "Animals exhibit variations in response to anoxia, trace oxygen conditions, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson324", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002425 ;
    owl:annotatedTarget "Variations in the specific actions or reactions in response to external or internal stimuli in response to the aggregation of proteins." .

[]
    oboInOwl:hasDbXref "GO:0008340", "WB:WBPaper00035872", "WB:WBPerson324", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002426 ;
    owl:annotatedTarget "The duration of viability in the adult phase of the life-cycle is lowered in response to the aggregation of proteins." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035872", "WB:WBPerson324", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002427 ;
    owl:annotatedTarget "Variations in the behavioral plasticity induced by the integration of two sensory signals in response to the aggregation of proteins." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041065", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002428 ;
    owl:annotatedTarget "Animals exhibit degeneration of the intestine, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00042060", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002429 ;
    owl:annotatedTarget "Animals exhibit variations in the degree to which some proteins are glycosylated, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041209", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002430 ;
    owl:annotatedTarget "Any variation in the extent of mitochondrial DNA damage observed compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041021", "WB:WBPerson7" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002431 ;
    owl:annotatedTarget "A telomerase-independent telomere maintenance pathway that allows for strains to survive in the absence of telomerase." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050011", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002432 ;
    owl:annotatedTarget "Animals do not respond with sleeping behavior induced through the EGF pathway. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050011", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002433 ;
    owl:annotatedTarget "Animals respond with sleeping behavior induced through the EGF pathway, more rigorously than control animals. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027723", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002434 ;
    owl:annotatedTarget "Animals exhibit variations in their response to mitochondrial stress, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002435 ;
    owl:annotatedTarget "Nematodes exposed to DNA damaging agents or conditions exhibit lower susceptibility to DNA damage than other animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002436 ;
    owl:annotatedTarget "Nematodes exposed to DNA damaging agents or conditions exhibit greater susceptibility to DNA damage than other animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003822", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002437 ;
    owl:annotatedTarget "Animals exhibit variations in the expression of repetitive exogenous DNA compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003822", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002438 ;
    owl:annotatedTarget "Animals exhibit reduced expression of repetitive exogenous DNA compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003822", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002439 ;
    owl:annotatedTarget "Animals exhibit increased expression of repetitive exogenous DNA compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002440 ;
    owl:annotatedTarget "Any perturbation that renders sperm incompetent at fertilizing an oocyte." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050613", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002441 ;
    owl:annotatedTarget "The time between two pumps of the pharynx is increased compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050613", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002442 ;
    owl:annotatedTarget "The duration of the contraction of the pharyngeal muscle during pumping is increased compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002443 ;
    owl:annotatedTarget "Any variation in the specific actions or reactions of the male that are associated with the protraction of the male copulatory spicules compared to control." .

[]
    oboInOwl:hasDbXref "GO:0019856", "WB:WBPerson324", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002444 ;
    owl:annotatedTarget "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025033", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002445 ;
    owl:annotatedTarget "Animals have one or more extra hypodermal cells, which are present in places they are normally not found, when compared to the number and location of these cells in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000184 ;
    owl:annotatedTarget "Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002446 ;
    owl:annotatedTarget "Animals exhibit variations in pharyngeal pumping rate in response to light, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002447 ;
    owl:annotatedTarget "Animals exhibit variations in the acute pharyngeal pumping response to light, during which the pharyngeal pumping rate initially (0-5 seconds after light exposure onset) decreases in response to light, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002448 ;
    owl:annotatedTarget "Animals exhibit an enhanced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a greater extent than in controls during the first 0-5 seconds after light exposure onset." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002449 ;
    owl:annotatedTarget "Animals exhibit a reduced acute pharyngeal pumping response to light, such that pharyngeal pumping rate decreases in response to light to a lesser extent than in controls during the first 0-5 seconds after light exposure onset." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002450 ;
    owl:annotatedTarget "Animals exhibit variations in the burst pharyngeal pumping response to light, during which the pharyngeal pumping rate slightly increases during the5-10 seconds after light exposure onset, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002451 ;
    owl:annotatedTarget "Animals exhibit an enhanced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a greater extent than in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002452 ;
    owl:annotatedTarget "Animals exhibit a reduced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a lesser extent than in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002453 ;
    owl:annotatedTarget "Animals exhibit variations in the recovery pharyngeal pumping response to light, during which the pharyngeal pumping rate slowly increases during the 0-10 seconds afterremoval of light exposure, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002454 ;
    owl:annotatedTarget "Animals exhibit an enhanced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increases to a greater extent than in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046411", "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002455 ;
    owl:annotatedTarget "Animals exhibit a reduced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increasesto a lesser extent than in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000185 ;
    owl:annotatedTarget "Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048388", "WB:WBPerson2987", "WB:WBPerson557", "WB:WBPerson9765" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002456 ;
    owl:annotatedTarget "Animals exhibit variations in the changes in calcium levels in response to light compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00026839", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002457 ;
    owl:annotatedTarget "Formation in the male of the egg-laying organ of female and hermaphrodite nematodes. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002458 ;
    owl:annotatedTarget "Any variation in the form, structure or composition of any part of an animal caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049531", "WB:WBPerson168", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002459 ;
    owl:annotatedTarget "Animals exhibit hyperinduction of expression of an antimicrobial peptide after an infection, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00038424", "WB:WBPaper00040946", "WB:WBPaper00049531", "WB:WBPerson168", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002460 ;
    owl:annotatedTarget "Animals exhibit no induction of expression of an antimicrobial peptide after an infection, unlike control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002461 ;
    owl:annotatedTarget "Pathogens exhibit decreased adherence to the surface of host animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049531", "WB:WBPerson168", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002462 ;
    owl:annotatedTarget "Pathogens exhibit increased adherence to the surface of host animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045644", "WB:WBPerson557", "WB:WBPerson625" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002463 ;
    owl:annotatedTarget "Male animals lack a copulatory hook." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00045644", "WB:WBPerson557", "WB:WBPerson625" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002464 ;
    owl:annotatedTarget "Male animals exhibit multiple copulatory hooks. In wild type C. elegans males, a single hook is normally present." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053651", "WB:WBPerson1370", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002465 ;
    owl:annotatedTarget "The pattern or state of ubiquitin modifications of histones varies from that of controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049616", "WB:WBPerson29150", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002466 ;
    owl:annotatedTarget "Variations in the processes that incorporate methyl groups to one or more bases within RNA, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053333", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002467 ;
    owl:annotatedTarget "Males continue to sire progeny significantly past the time reproduction stops in control animals or show a slower decline in mating efficiency compared to age-matched control males." .

[]
    oboInOwl:hasDbXref "GO:0006417", "WB:WBPaper00046894", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002468 ;
    owl:annotatedTarget "Animals exhibit a reduction in the rate of the chemical reactions and pathways resulting in the formation of a protein, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041802", "WB:WBPerson3192", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002469 ;
    owl:annotatedTarget "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053681", "WB:WBPerson2136", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002470 ;
    owl:annotatedTarget "Animals exhibit variations in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053681", "WB:WBPerson2136", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002471 ;
    owl:annotatedTarget "Animals exhibit an increase in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053681", "WB:WBPerson2136", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002472 ;
    owl:annotatedTarget "Animals exhibit a reduction in the length of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0006914", "WB:WBPaper00046758", "WB:WBPerson2242", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002473 ;
    owl:annotatedTarget "Animals fail to undergo the cellular catabolic process in which cells digest parts of their own cytoplasm." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053019", "WB:WBPerson24802", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002474 ;
    owl:annotatedTarget "Animals are less prone to infection by virus compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049351", "WB:WBPerson2693", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002475 ;
    owl:annotatedTarget "Animals vary in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049351", "WB:WBPerson2693", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002476 ;
    owl:annotatedTarget "Animals have an increase in the distance between most anterior and the most posterior ends of the pharynx from that observed in control animals." .

[]
    oboInOwl:hasDbXref "GO:0005840", "WB:WBPaper00052855", "WB:WBPerson15276", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002477 ;
    owl:annotatedTarget "Any variation in the subcellular localization of the ribosome compared to control. The ribosome is an intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053323", "WB:WBPerson557", "WB:WBPerson9270" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002478 ;
    owl:annotatedTarget "Any variation in the cellular and molecular pathways in a neuron in response to having its axon severed compared to severing in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053323", "WB:WBPerson557", "WB:WBPerson9270" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002479 ;
    owl:annotatedTarget "Any increase in regenerative regrowth of axons compared to control animals." .

[]
    oboInOwl:hasDbXref "GO:0006783", "WB:WBPaper00049976", "WB:WBPerson16107", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002480 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." .

[]
    oboInOwl:hasDbXref "GO:0006783", "WB:WBPaper00049976", "WB:WBPerson16107", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002481 ;
    owl:annotatedTarget "Animals exhibit a decrease in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." .

[]
    oboInOwl:hasDbXref "GO:0006783", "WB:WBPaper00049976", "WB:WBPerson16107", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002482 ;
    owl:annotatedTarget "Animals exhibit an increase in the amount of heme compared to control animals. Heme is any compound of iron complexed in a porphyrin (tetrapyrrole) ring." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046695", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002483 ;
    owl:annotatedTarget "Animals are less prone to infection by a fungus compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00055850", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002484 ;
    owl:annotatedTarget "Animals exhibit variations in fluidity of cell membranes, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000017 ;
    owl:annotatedTarget "Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050421", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002485 ;
    owl:annotatedTarget "Any variation in the morphological appearance of germline precursor cells compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050421", "WB:WBPerson2987", "WB:WBPerson35710" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002486 ;
    owl:annotatedTarget "Animals exhibit persistent cellular lobes of the primordial germ cells Z2 and/or Z3 at the L1 larval stage or later, in contrast to wild type animals" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049837", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002487 ;
    owl:annotatedTarget "Animals exhibit variations in the integrity of the intestine, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049837", "WB:WBPerson14863", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002488 ;
    owl:annotatedTarget "Animals exhibit an increase in the integrity of the intestine, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002489 ;
    owl:annotatedTarget "Animals exhibit a reduction in the integrity of the intestine, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004283", "WB:WBPaper00006029", "WB:WBPaper00026706", "WB:WBPaper00027335", "WB:WBPaper00031901", "WB:WBPaper00032090", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002490 ;
    owl:annotatedTarget "Neurons exhibit axon outgrowth in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "GO:0048477", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000186 ;
    owl:annotatedTarget "Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003665", "WB:WBPaper00004340", "WB:WBPaper00027335", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002491 ;
    owl:annotatedTarget "Neurons exhibit neurite outgrowth in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000187 ;
    owl:annotatedTarget "The overall structure or appearance of fertilized oocytes that are laid has every part of their surface equidistant from the center." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00035201", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002492 ;
    owl:annotatedTarget "Animals exhibit one or more body wall muscle cells in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000188 ;
    owl:annotatedTarget "Any variation in the 'arm-like' form, structure or composition of the specialized tissue of the reproductive tract that produces gametes compared to control. In C. elegans the reproductive tract in the hermaphrodite has two equivalent gonad 'arms', while the male has a one-armed gonad." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003331", "WB:WBPaper00003719", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002493 ;
    owl:annotatedTarget "Animals exhibit one or more cells of a particular type in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002871", "WB:WBPaper00003645", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002494 ;
    owl:annotatedTarget "Animals exhibit one or more endodermal cells in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00025033", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002495 ;
    owl:annotatedTarget "Animals exhibit one or more hypodermal cells in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000635", "WB:WBPaper00027335", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002496 ;
    owl:annotatedTarget "Animals exhibit one or more neurons in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003574", "WB:WBPaper00003645", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002497 ;
    owl:annotatedTarget "Animals exhibit one or more pharyngeal muscle cells in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031604", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002498 ;
    owl:annotatedTarget "Animals exhibit one or more organs of a particular type in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031604", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002499 ;
    owl:annotatedTarget "Animals exhibit one or more vulvae in locations not normally found in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005599", "WB:WBPaper00006061", "WB:WBPaper00030892", "WB:WBPaper00033469", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002501 ;
    owl:annotatedTarget "One or more cells of the early embryo (one-cell stage to four-cell stage) exhibit one or more cleavage furrows in locations not normally found in control cells." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046534", "WB:WBPerson113", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002502 ;
    owl:annotatedTarget "Animals exhibit an increase in the covalent addition of an acetyl group to one or more native amino acid side chains in proteins." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046534", "WB:WBPerson113", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002503 ;
    owl:annotatedTarget "Animals exhibit an increase the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040246", "WB:WBPaper00045292", "WB:WBPerson2987", "WB:WBPerson3965" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002504 ;
    owl:annotatedTarget "Infected animals exhibit a reduction in the release of pathogens back into the environment, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044624", "WB:WBPerson2706", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002505 ;
    owl:annotatedTarget "Infected animals exhibit variations in the clearance of pathogen infection compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044624", "WB:WBPerson2706", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002506 ;
    owl:annotatedTarget "Infected animals exhibit an increased rate of clearance of pathogen infection compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044624", "WB:WBPerson2706", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002507 ;
    owl:annotatedTarget "Infected animals exhibit a decreased rate of clearance of pathogen infection compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053165", "WB:WBPerson2987", "WB:WBPerson3252" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002508 ;
    owl:annotatedTarget "Animals produce an excess number of neurons compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053165", "WB:WBPerson2987", "WB:WBPerson3252" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002509 ;
    owl:annotatedTarget "Animals produce an excess number of dopaminergic neurons compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053165", "WB:WBPerson2987", "WB:WBPerson3252" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002510 ;
    owl:annotatedTarget "Animals exhibit fewer neurons compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053165", "WB:WBPerson2987", "WB:WBPerson3252" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002511 ;
    owl:annotatedTarget "Animals exhibit fewer glutamatergic neurons compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00027006", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000189 ;
    owl:annotatedTarget "Hypodermal cells fail to be organized in the same manner as observed in control animals. In C. elegans, hypodermal cells typically organize into distinct dorsal, lateral and ventral rows and cover the entire body." .

[]
    oboInOwl:hasDbXref "GO:0040040", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002512 ;
    owl:annotatedTarget "Variations in behavior that is dependent upon the sensation of temperature, compared to control." .

[]
    oboInOwl:hasDbXref "GO:0043052", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002513 ;
    owl:annotatedTarget "Any variation in the directed movement of a worm in response to a specific temperature gradient compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson261", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002514 ;
    owl:annotatedTarget "Animals do not exhibit backward locomotion under conditions that induce backward locomotion in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00055957", "WB:WBPerson2987", "WB:WBPerson919" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002515 ;
    owl:annotatedTarget "Animals exhibit a defective response to pathogens." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046657", "WB:WBPaper00056369", "WB:WBPerson2987", "WB:WBPerson9270" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002516 ;
    owl:annotatedTarget "Animals exhibit variations, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Variations in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect variations in neuromuscular efficacy of locomotion." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046657", "WB:WBPaper00056369", "WB:WBPerson2987", "WB:WBPerson9270" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002517 ;
    owl:annotatedTarget "Animals exhibit a reduction, compared to control, in the distance traveled in a burrowing assay, in which animals are placed in a tube, separated from an attractant by solid medium through which the worms can burrow. Reductions in distance traveled during the burrowing assay, when controlled for chemosensation defects, have been suggested to reflect deficits in neuromuscular efficacy of locomotion." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056369", "WB:WBPerson2987", "WB:WBPerson9270" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002518 ;
    owl:annotatedTarget "The length of one or more axons is abnormal compared to the length of the corresponding axon(s) in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056369", "WB:WBPerson2987", "WB:WBPerson9270" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002519 ;
    owl:annotatedTarget "The length of one or more axons is reduced compared to the length of the corresponding axon(s) in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049389", "WB:WBPerson2987", "WB:WBPerson30255" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002520 ;
    owl:annotatedTarget "One or more cells exhibit variations in the morphology of one or more gap junction plaques, sets of associated gap junctions, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049389", "WB:WBPerson2987", "WB:WBPerson30255" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002521 ;
    owl:annotatedTarget "One or more cells exhibit an increase in number of gap junction plaques, sets of associated gap junctions, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049938", "WB:WBPerson2987", "WB:WBPerson6498" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002522 ;
    owl:annotatedTarget "Animals exhibit variations in the recovery from L1 larvae developmental arrest in response to a lack of food (starvation) available in the environment." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049938", "WB:WBPerson2987", "WB:WBPerson34124", "WB:WBPerson6498" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002523 ;
    owl:annotatedTarget "Animals exhibit a slow recovery from starvation-induced L1 arrest, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056452", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002524 ;
    owl:annotatedTarget "Animals are more sensitive to the depletion of molybdenum cofactor from the diet compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024451", "WB:WBPaper00026641", "WB:WBPaper00032936", "WB:WBPaper00045849", "WB:WBPaper00056452", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002525 ;
    owl:annotatedTarget "Animals exhibit variations in their response to diet, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056452", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002526 ;
    owl:annotatedTarget "Animals exhibit variations in the response to the depletion of molybdenum cofactor from the diet compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00004052", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002527 ;
    owl:annotatedTarget "Animals in the dauer larval stage exhibit variations in their physiology (any biological process including but not limited to development, behavior, or metabolism) compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041677", "WB:WBPerson2987", "WB:WBPerson5649" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002528 ;
    owl:annotatedTarget "Animals (or cells) exhibit defects in the ability to produce mature microRNAs (miRNAs) from a miRNA locus. The defects could be at the level of miRNA transcription, pri-miRNA processing, and/or pre-miRNA processing." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056554", "WB:WBPerson2987", "WB:WBPerson5649" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002529 ;
    owl:annotatedTarget "Animals exhibit defects or impairments in the functioning of the proteasome." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053570", "WB:WBPerson2987", "WB:WBPerson9270" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002530 ;
    owl:annotatedTarget "The level of phosphatidylserine exposed on the external axonal membrane following transection (axotomy) is changed compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040312", "WB:WBPaper00041104", "WB:WBPaper00053507", "WB:WBPerson2987", "WB:WBPerson3859" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002531 ;
    owl:annotatedTarget "Animals exhibit variations in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053507", "WB:WBPerson2987", "WB:WBPerson3859" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002532 ;
    owl:annotatedTarget "Animals exhibit defects in allogenic (non-self) organelle autophagy, or allophagy, a macroautophagy process whereby organelles of non-self origin, like paternal mitochondria from sperm in a newly fertilized oocyte, are selectively degraded." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00031865", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002534 ;
    owl:annotatedTarget "Animals exhibit variations in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00000793", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002535 ;
    owl:annotatedTarget "Animals exhibit variations in the extent to which one or more sensory neurons associated with sensilla (typically one or more amphids and/or phasmids) take up dye from the environment, compared to controls. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044160", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002536 ;
    owl:annotatedTarget "Animals exhibit germ cells with a number of P granules that differs from control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044160", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002537 ;
    owl:annotatedTarget "Animals exhibit germ cells with a reduced number of P granules compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056137", "WB:WBPerson2987", "WB:WBPerson30989" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002538 ;
    owl:annotatedTarget "Any variation in the series of molecular signals in which the spermatheca uses calcium ions to convert an extracellular signal into a response, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00047109", "WB:WBPerson15627", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002539 ;
    owl:annotatedTarget "Animals exhibit an increase in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053007", "WB:WBPerson262", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002540 ;
    owl:annotatedTarget "Animals exhibit a reduced rate of lawn/food leaving events, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00032243", "WB:WBPaper00032356", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002541 ;
    owl:annotatedTarget "Programmed cell death of germ cells caused by exposure to ionizing energy occurs to a lesser extent than it does in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056796", "WB:WBPerson2987", "WB:WBPerson32254" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002542 ;
    owl:annotatedTarget "Cells exhibit specific regions of chromatin (e.g. an integrated array reporter) that localize to different regions within the nucleus, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053883", "WB:WBPerson2987", "WB:WBPerson31184" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002543 ;
    owl:annotatedTarget "Animals accumulate a greater number of mitochondrial genetic lesions than control animals in the absence of an externally controlled mutagen." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056139", "WB:WBPerson2987", "WB:WBPerson3878" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002544 ;
    owl:annotatedTarget "Normally beneficial (or otherwise harmless, non-pathogenic) commensal Enterobacter bacteria, for example Enterobacter cloacae, become pathogenic to animals, unlike in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056139", "WB:WBPerson2987", "WB:WBPerson3878" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002545 ;
    owl:annotatedTarget "Animals exhibit variations in their response to bacteria (pathogenic or non-pathogenic), compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056139", "WB:WBPerson2987", "WB:WBPerson3878" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002546 ;
    owl:annotatedTarget "Animals exhibit variations in the load of bacteria, of a particular clade or in general, in the gut, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056139", "WB:WBPerson2987", "WB:WBPerson3878" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002547 ;
    owl:annotatedTarget "Animals exhibit a greater abundance of bacteria of the Enterobacteriaceae family in the gut, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040432", "WB:WBPerson2987", "WB:WBPerson720" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002548 ;
    owl:annotatedTarget "Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040432", "WB:WBPerson2987", "WB:WBPerson720" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002549 ;
    owl:annotatedTarget "Animals exhibit an increase in the rate at which spontaneous backward locomotion is initiated compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00040432", "WB:WBPerson2987", "WB:WBPerson720" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002550 ;
    owl:annotatedTarget "Animals exhibit a kinker phenotype that is due to conflicting, simultaneous forward and backward propagating bending waves, and over time has a tendency to move slowly backward due to a dominating reversal neural circuit." .

[]
    oboInOwl:hasDbXref "GO:0043054", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000190 ;
    owl:annotatedTarget "Animals fail to exit from the facultative diapause of the dauer larval stage of nematode development." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002551 ;
    owl:annotatedTarget "A phenotype affecting a particular anatomical entity." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002552 ;
    owl:annotatedTarget "A phenotype affecting a particular cell." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002553 ;
    owl:annotatedTarget "A phenotype affecting a particular organ." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002554 ;
    owl:annotatedTarget "A phenotype affecting a particular organ system." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002555 ;
    owl:annotatedTarget "A phenotype affecting the whole organism." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002556 ;
    owl:annotatedTarget "A phenotype affecting a particular tissue." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002557 ;
    owl:annotatedTarget "A phenotype affecting a particular body region." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002558 ;
    owl:annotatedTarget "A phenotype affecting a particular extracellular component." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002559 ;
    owl:annotatedTarget "Animals exhibit abnormalities in their burrowing behavior, in which animals burrow into a solid medium, such as agar, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00058743", "WB:WBPerson2987", "WB:WBPerson712" ;
    a owl:Axiom ;
    rdfs:comment "WB:WBPaper00002770" ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002560 ;
    owl:annotatedTarget "Greater quantities of worms burrow into and stay below the surface of the agar when high densities of nematodes are maintained on agar compared to controls (Hodgkin and Doniach, 1997)." .

[]
    oboInOwl:hasDbXref "GO:0034058", "WB:WBPaper00029049", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002561 ;
    owl:annotatedTarget "Cells exhibit defects in the homotypic fusion of endosomes." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00029049", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002562 ;
    owl:annotatedTarget "Cells exhibit variations or abnormalities in their maintenance of lysosome function, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002563 ;
    owl:annotatedTarget "Animals exhibit variations in any physical or chemical process required for the neuron to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000191 ;
    owl:annotatedTarget "Animals exhibit variations in their response to a situation when there is too high a density of nematodes to be supported by the available amount of food and space compared to that observed in control animals (Wormatlas)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036296", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002564 ;
    owl:annotatedTarget "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036296", "WB:WBPerson2987", "WB:WBPerson3142" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002565 ;
    owl:annotatedTarget "Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036296", "WB:WBPerson2987", "WB:WBPerson3142" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002566 ;
    owl:annotatedTarget "Animals exhibit variations in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036296", "WB:WBPerson2987", "WB:WBPerson3142" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002567 ;
    owl:annotatedTarget "Animals are deficient in their recalled and repeated responses to olfactory stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00036296", "WB:WBPerson2987", "WB:WBPerson3142" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002568 ;
    owl:annotatedTarget "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the long term, compared to controls. Long-term associative memory is memory that lasts for hours to days after the associative learning (training) event(s)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002569 ;
    owl:annotatedTarget "Any variation in the progression of the hypodermis over time, from its formation to its mature state compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000192 ;
    owl:annotatedTarget "Any variation that results in the misregulation of enzymatic activity such that catalysis occurs at a constant rate regardless of physiological demand or the concentration of a substrate." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson6609" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002570 ;
    owl:annotatedTarget "Cessation of development during the gastrulation stage of embryonic development. In C. elegans, gastrulation occurs 100-290 minutes after first cleavage at 20 degrees Centigrade when the embryo develops from 28 cells to 421 cells (during the proliferating embryo life stage)." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson6609" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002571 ;
    owl:annotatedTarget "Embryos exhibit a failure to enclose the anterior embryo region with hypodermis during the comma to early elongation stage of embryonic development." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056229", "WB:WBPerson27070", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002572 ;
    owl:annotatedTarget "Animals exhibit variations in mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000193 ;
    owl:annotatedTarget "Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056229", "WB:WBPerson27070", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002573 ;
    owl:annotatedTarget "Animals exhibit reduced levels of mitophagy, the selective autophagy process in which a mitochondrion is degraded by macroautophagy, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050756", "WB:WBPerson2987", "WB:WBPerson5662" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002574 ;
    owl:annotatedTarget "Animals exhibit abnormal amounts of variation in gene expression level between individual animals, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002575 ;
    owl:annotatedTarget "Animals exhibit abnormal gene expression levels, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000194 ;
    owl:annotatedTarget "Variations in the placement of the polar body formed in the first division of meiosis of a primary oocyte, compared to control. A polar body is the by-product of meiosis (destined to degenerate) in female or hermaphrodite animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050756", "WB:WBPerson2987", "WB:WBPerson5662" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002576 ;
    owl:annotatedTarget "Animals exhibit reduced amounts of variation in gene expression level between individual animals, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00057139", "WB:WBPerson2987", "WB:WBPerson32869" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002577 ;
    owl:annotatedTarget "Animals exhibit variations in the composition of basement membranes, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00057139", "WB:WBPerson2987", "WB:WBPerson32869" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002578 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of laminin in basement membranes, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00057139", "WB:WBPerson2987", "WB:WBPerson32869" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002579 ;
    owl:annotatedTarget "Animals exhibit variations in the amount of type IV collagen in basement membranes, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056010", "WB:WBPerson13958", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002580 ;
    owl:annotatedTarget "One or more cells exhibit changes in the variability of cell position, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00056010", "WB:WBPerson13958", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002581 ;
    owl:annotatedTarget "One or more cells exhibit increases in the variability of cell position, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048837", "WB:WBPerson18607", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002582 ;
    owl:annotatedTarget "Animals exhibit variations in miniature inhibitory post-synaptic currents (mIPSC), compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048837", "WB:WBPerson18607", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002583 ;
    owl:annotatedTarget "Animals exhibit increased amplitude of miniature inhibitory post-synaptic currents (mIPSC), compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00024241", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002584 ;
    owl:annotatedTarget "Animals survive longer, or do not respond to the same degree as control animals under similar conditions of bisphenol A exposure." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053031", "WB:WBPerson2987", "WB:WBPerson38478" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002585 ;
    owl:annotatedTarget "Pristionchus pacificus: Animals exhibit abnormal predatory behavior, compared to controls." .

[]
    oboInOwl:hasDbXref "GO:0040039", "WB:WBPaper00003598", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000195 ;
    owl:annotatedTarget "Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053031", "WB:WBPerson2987", "WB:WBPerson38478" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002586 ;
    owl:annotatedTarget "Pristionchus pacificus: Animals exhibit reduced predatory feeding behavior, indicated by reduced predation success, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00058750", "WB:WBPerson2987", "WB:WBPerson43910" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002587 ;
    owl:annotatedTarget "Animals are impaired in their burrowing ability compared to control animals in a Pluronic gel-based burrowing assay." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00037647" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002588 ;
    owl:annotatedTarget "Animals exhibit variations or abnormalities in the structure, integrity, function, or quality of basement membranes, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson58" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002589 ;
    owl:annotatedTarget "Animals exhibit a reduction in neuron degeneration, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00046064", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002590 ;
    owl:annotatedTarget "The linker cell of male animals becomes detached from the rest of the male gonad." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00033050", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002591 ;
    owl:annotatedTarget "One or more neurons of the animal exhibit one or more dendrites with reduced length compared to the corresponding dendrites in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00030928", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002592 ;
    owl:annotatedTarget "Animals exhibit variations in their response to changes in gravitational force, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006159", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002593 ;
    owl:annotatedTarget "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00006159", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002594 ;
    owl:annotatedTarget "Any variation in the decrease in a behavioral response to a repeated plate tap stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00052970", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002595 ;
    owl:annotatedTarget "The reduction in brood size caused by sleep deprivation is enhanced, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00052970", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002596 ;
    owl:annotatedTarget "The reduction in brood size caused by sleep deprivation is suppressed, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00059641", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002597 ;
    owl:annotatedTarget "Variations in the behavioral plasticity induced by the integration of two sensory signals (one of which is gustation (taste)) compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype have an abnormal response to the trained stimuli compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00059641", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002598 ;
    owl:annotatedTarget "Variations in the aversion of animals to substances sensed by gustation (taste) previously associated with an aversive stimuli during a gustation training protocol, compared to control. For example, C. elegans animals can be trained to associate the taste of a substance (e.g. sodium chloride, normally an attractant) to an aversive stimuli (e.g. starvation) so that trained worms will avoid the substance in the absence of the aversive stimuli. Animals with this phenotype will not exhibit the same aversion to the substance as compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041586", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002599 ;
    owl:annotatedTarget "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the long term. Long-term memory is memory that lasts for hours to days after the learning (training) event(s)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041586", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002600 ;
    owl:annotatedTarget "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control, over the short term. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041586", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002601 ;
    owl:annotatedTarget "Animals exhibit variations in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms over the short term, compared to controls. Short-term memory is memory that lasts for minutes to hours after the learning (training) event(s)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00049647", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002602 ;
    owl:annotatedTarget "Animals exhibit a decrease in the rate at which spontaneous backward locomotion is initiated compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00059748", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002603 ;
    owl:annotatedTarget "Animals exhibit an abnormal response to toxic proteins, either via exposure in the environment or expressed within the organism, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00059748", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002604 ;
    owl:annotatedTarget "Animals exhibit an abnormal response to toxic dipeptide repeat proteins, either via exposure in the environment or expressed within the organism, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00059748", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002605 ;
    owl:annotatedTarget "Normally toxic dipeptide repeat proteins appear to be less toxic to animals, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028466", "WB:WBPaper00059770", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002606 ;
    owl:annotatedTarget "Animals exhibit reduced necrotic cell death, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00042522", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002607 ;
    owl:annotatedTarget "One or more cellular nuclei exhibit an abnormal size, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003046" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002608 ;
    owl:annotatedTarget "A body elongation defect in which embryos develop abnormally bulged dorsal surfaces." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003046" ;
    a owl:Axiom ;
    owl:annotatedProperty rdfs:comment ;
    owl:annotatedSource obo:WBPhenotype_0002608 ;
    owl:annotatedTarget "\"After standard ethylmethane sulfonate mutagenesis, we screened directly for mutant embryos that are defective in body elongation. We isolated 13 recessive, zygotic-lethal mutants that, in addition to failing to elongate properly, show abnormally bulged dorsal surfaces (Fig. 1B). We call this novel phenotype Hmp (humpback); this phenotype contrasts with previously described elongation-defective Pat mutants that display bulges at variable positions (Williams and Waterston, 1994).\"" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003046", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002609 ;
    owl:annotatedTarget "An anterior enclosure defect in which the anterior portion of the embryo, unenclosed by the hypodermis, bulges to form a hammerhead shape." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003046" ;
    a owl:Axiom ;
    owl:annotatedProperty oboInOwl:hasExactSynonym ;
    owl:annotatedSource obo:WBPhenotype_0002609 ;
    owl:annotatedTarget "Hmr" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00003046" ;
    a owl:Axiom ;
    owl:annotatedProperty rdfs:comment ;
    owl:annotatedSource obo:WBPhenotype_0002609 ;
    owl:annotatedTarget "\"However, in the remaining hmr-1 mutants the hypodermis fails to fully enclose the embryo. We call this phenotype Hmr (hammerhead; see Fig. 1F).\"" .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044285", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002610 ;
    owl:annotatedTarget "Apoptosis occurs in cells or cell types that do not undergo apoptosis in controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050908", "WB:WBPerson2987", "WB:WBPerson3569" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002611 ;
    owl:annotatedTarget "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is impaired." .

[]
    oboInOwl:hasDbXref "GO:0099636", "WB:WBPaper00050908", "WB:WBPerson2987", "WB:WBPerson3569" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002612 ;
    owl:annotatedTarget "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is abnormal compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050908", "WB:WBPerson2987", "WB:WBPerson3569" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002613 ;
    owl:annotatedTarget "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell undergoing meiosis is abnormal compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00059527", "WB:WBPerson2439", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002614 ;
    owl:annotatedTarget "Genes normally silenced within heterochromatin are abnoramally de-repressed and exhibit expression, unlike controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041673", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002615 ;
    owl:annotatedTarget "Animals accumulate vacuoles in an abnormal manner in cells, tissues, and/or organs of the animal." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041673", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002616 ;
    owl:annotatedTarget "Cells exhibit an abnormal intracellular level (amount) of calcium, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041673", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002617 ;
    owl:annotatedTarget "Cells exhibit a higher level of calcium in the cytosol, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:cab" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000196 ;
    owl:annotatedTarget "The morphological appearance of distal tip cells is varied compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041673", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002618 ;
    owl:annotatedTarget "Cells exhibit a lower level of calcium in the cytosol, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041673", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002619 ;
    owl:annotatedTarget "Animals exhibit increased occurrence of cell death, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00041673", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002620 ;
    owl:annotatedTarget "Animals exhibit decreased occurrence of cell death, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00053771", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002621 ;
    owl:annotatedTarget "Animals exhibit a decrease in the expression of one or more known, endogenous, antimicrobial genes, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00059214", "WB:WBPerson2987", "WB:WBPerson499" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002622 ;
    owl:annotatedTarget "Animals exhibit decreased recruitment of actin to a site of injury, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00059214", "WB:WBPerson2987", "WB:WBPerson499" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002623 ;
    owl:annotatedTarget "Animals exhibit no induction of expression of an antimicrobial peptide after an injury, unlike control animals." .

[]
    oboInOwl:hasDbXref "PMID:32973031", "WB:WBPerson2987", "WB:WBPerson36183" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002624 ;
    owl:annotatedTarget "Cells display reduced incorporation of the thymidine analogue 5-Ethynyl-2'-deoxyuridine (EdU), suggesting reduced cell proliferation. Incorporation of EdU is an indication of active DNA synthesis and thus an indication of cells proceeding through the cell cycle." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2987", "WB:WBPerson36183" ;
    a owl:Axiom ;
    rdfs:comment "PMID:32973031" ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002625 ;
    owl:annotatedTarget "Animals exhibit visible, structural degeneration of the head, unlike control animals." .

[]
    oboInOwl:hasDbXref "PMID:32973031", "WB:WBPerson2987", "WB:WBPerson36183" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002626 ;
    owl:annotatedTarget "Animals exhibit an abnormal attachment (or lack thereof) to a substrate, compared to controls. For some parasitic worms, attachment to host tissue surfaces, like endothelium, is a necessary behavior for their life cycle." .

[]
    oboInOwl:hasDbXref "PMID:32973031", "WB:WBPerson2987", "WB:WBPerson36183" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002627 ;
    owl:annotatedTarget "Animals exhibit an abnormal attachment (or lack thereof) to a substrate in vitro, compared to controls." .

[]
    oboInOwl:hasDbXref "PMID:32973031", "WB:WBPerson2987", "WB:WBPerson36183" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002628 ;
    owl:annotatedTarget "Animals exhibit a reduced attachment to a substrate in vitro, compared to controls." .

[]
    oboInOwl:hasDbXref "PMID:32973031", "WB:WBPerson2987", "WB:WBPerson36183" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002629 ;
    owl:annotatedTarget "Animals exhibit edema (swelling) of the intestine, compared to control animals. This swelling is distinct from distension of the intestinal lumen (swollen intestinal lumen)." .

[]
    oboInOwl:hasDbXref "PMID:32973031", "WB:WBPerson2987", "WB:WBPerson36183" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002630 ;
    owl:annotatedTarget "Animals exhibit degeneration of the epithelial system (skin, integument or tegument), compared to control animals." .

[]
    oboInOwl:hasDbXref "PMID:32973031", "WB:WBPerson2987", "WB:WBPerson36183" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002631 ;
    owl:annotatedTarget "Animals exhibit edema (swelling) of one or more tissues, compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061371", "WB:WBPerson2987", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002632 ;
    owl:annotatedTarget "Animals exhibit cells with an abnormal degree of chromatin accessibility, compared to controls, detected using techniques such as ATAC-seq (Assay for Transposase-Accessible Chromatin using sequencing)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00055692", "WB:WBPerson2987", "WB:WBPerson43879" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002633 ;
    owl:annotatedTarget "Animals exhibit a pharynx that recedes into the animal's interior such that the animal cannot feed." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00050013", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002634 ;
    owl:annotatedTarget "Animals exhibit a resistance to endoplasmic reticulum (ER) stressors such as an accumulation of unfolded proteins or the presence of chemicals that induce ER stress, such as dithiothreitol (DDT) or tunicamycin, compared to controls. This may mean that animals fare better than controls in terms of survival or some metric of health when exposed to an inducer of ER stress." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00052963", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002635 ;
    owl:annotatedTarget "Animals shed fragments of epidermis into the surrounding environment, unlike controls. In embryos, these fragments can be seen in the extra-embryonic space." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00048885", "WB:WBPerson14737", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002636 ;
    owl:annotatedTarget "One or more cells of the animal exhibit chromatin that has become detached from the nuclear periphery, unlike controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00055104", "WB:WBPerson2987", "WB:WBPerson35689" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002637 ;
    owl:annotatedTarget "Animals (or cells of the animal) exhibit reduced levels of iron in the body (or cells) compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00060871", "WB:WBPerson2987", "WB:WBPerson53483" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002638 ;
    owl:annotatedTarget "Animals are more prone to infection, sickness and/or death caused by oomycete pathogens compared to control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPerson10314", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002639 ;
    owl:annotatedTarget "Animals exhibit specific or general variations in the composition of the microbiome at a body site compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061220", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002640 ;
    owl:annotatedTarget "The physical strength or integrity of the cuticle is decreased compared to that observed for control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061220", "WB:WBPerson2987", "WB:WBPerson3900" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002641 ;
    owl:annotatedTarget "The cuticle of animals becomes more permeable to dyes or stains, such as Hoechst 33258, or other substances compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061220", "WB:WBPerson2987", "WB:WBPerson3900" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002642 ;
    owl:annotatedTarget "Animals exposed to an exogenous chemical exhibit an abnormal accumulation of this chemical in the body of the animals, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061220", "WB:WBPerson2987", "WB:WBPerson3900" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002643 ;
    owl:annotatedTarget "Animals exposed to an exogenous chemical exhibit an abnormal increase in accumulation of this chemical in the body of the animals, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061677", "WB:WBPerson2987", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002644 ;
    owl:annotatedTarget "Animals do not respond to the edge or gap in the medium surface they were supported on in the same manner as controls. In Mitchell et al., the precipice response was defined to be that within 2 seconds of the nose moving off the edge of the agar chunk, the worm begins a reversal that completes at least one full sine wave." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00060029", "WB:WBPerson14884", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002645 ;
    owl:annotatedTarget "Animals exhibit an abnormal recovery from heat stress, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00060029" ;
    a owl:Axiom ;
    owl:annotatedProperty rdfs:comment ;
    owl:annotatedSource obo:WBPhenotype_0002645 ;
    owl:annotatedTarget "Exposure of wild type worms to a 6 h heat shock at 33°C led to a 20% decrease in worms with normal movement after a 48 h recovery at 20°C." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00060029", "WB:WBPerson14884", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002646 ;
    owl:annotatedTarget "Animals exhibit reduced recovery from heat stress compared to controls. Reduced recovery may be indicated, for example, by a decrease in normal movement, such as uncoordinated or jerky movement or paralysis, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043988", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002647 ;
    owl:annotatedTarget "Animals display variations in the structure, organization of components, or spatial pattern of the neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00043988", "WB:WBPerson2987", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002648 ;
    owl:annotatedTarget "Animals display variations in the number or pattern of neuronal extensions that carry afferent (incoming) action potentials towards the cell body, compared to that observed in control animals." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00060230", "WB:WBPerson2987", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002649 ;
    owl:annotatedTarget "Characteristic response to chemicals with respect to egg-laying behavior varies compared to control." .

[]
    oboInOwl:hasDbXref "GO:0031128", "WB:WBPerson2021" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0000197 ;
    owl:annotatedTarget "Variations in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling)." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00060230", "WB:WBPerson2987", "WB:WBPerson712" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002650 ;
    owl:annotatedTarget "Characteristic response to extracted lipopolysaccharide from pathogens with respect to egg-laying behavior varies compared to control conditions." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061698", "WB:WBPerson23531", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002651 ;
    owl:annotatedTarget "Cells exhibit an abnormal production of exophers, large (approximately four microns in diameter) membrane-bound extracellular vesicles that are released by budding out of cells into the extracellular space, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061698", "WB:WBPerson23531", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002652 ;
    owl:annotatedTarget "Cells exhibit a increase in production of exophers compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061698", "WB:WBPerson23531", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002653 ;
    owl:annotatedTarget "Cells exhibit a decrease in production of exophers compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061698", "WB:WBPerson23531", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002654 ;
    owl:annotatedTarget "Muscle cells exhibit an abnormal production of exophers compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061698", "WB:WBPerson23531", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002655 ;
    owl:annotatedTarget "Muscle cells exhibit a decrease in production of exophers compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061698", "WB:WBPerson23531", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002656 ;
    owl:annotatedTarget "Muscle cells exhibit an increase in production of exophers compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00060877", "WB:WBPerson2987", "WB:WBPerson488" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002657 ;
    owl:annotatedTarget "Animals exhibit intolerance (e.g. lethality or significant growth defect) when exposed to saturated fatty acids via the diet, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061159", "WB:WBPerson1754", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002658 ;
    owl:annotatedTarget "Animals exhibit variations in muscle strength, as measured by a strength determining assay, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00061159", "WB:WBPerson1754", "WB:WBPerson2987" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002659 ;
    owl:annotatedTarget "Animals exhibit a decrease in muscle strength, as measured by a strength determining assay, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00044909", "WB:WBPerson2987", "WB:WBPerson5747" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002660 ;
    owl:annotatedTarget "Animals exhibit a depletion of germline stem cells, compared to controls." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00064532", "WB:WBPerson2987", "WB:WBPerson38719" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002661 ;
    owl:annotatedTarget "Genes, whose expression is typically induced by an innate immune response, are actively expressed under conditions which would not normally induce an innate immune response gene expression program." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00064532", "WB:WBPerson2987", "WB:WBPerson38719" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002662 ;
    owl:annotatedTarget "Animals exhibit an increase in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00064071", "WB:WBPerson2987", "WB:WBPerson58409" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0002663 ;
    owl:annotatedTarget "Cells of the animal exhibit variations in the intracellular lipid surveillance response, responsible for responding to and addressing lipid depletion inside of cells, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004001 ;
    owl:annotatedTarget "Any variation in the specific actions or reactions of a hermaphrodite during mating compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005109", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004002 ;
    owl:annotatedTarget "Animals exhibit defects in the production of the sensory signal to attract males." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00005109", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004003 ;
    owl:annotatedTarget "Males exhibit defects in their response to the mate-finding cue." .

[]
    oboInOwl:hasDbXref "GO:0034606", "WB:WBPaper00000392", "WB:WBPaper00002109", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004004 ;
    owl:annotatedTarget "The inability of a male to respond properly to a potential mate after contact. In C.elegans, proper response includes apposing the ventral side of his tail to the hermaphrodite's body and swimming backward." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004005 ;
    owl:annotatedTarget "Males exhibit variations in mating behavior prior to contacting its mate compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004006 ;
    owl:annotatedTarget "Males exhibit variations in mating behavior after contacting its mate compared to control." .

[]
    oboInOwl:hasDbXref "GO:0034609", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004007 ;
    owl:annotatedTarget "Males exhibit defects in the continuous prodding of spicule tips at the vulva prior to prolonged spicule insertion." .

[]
    oboInOwl:hasDbXref "GO:0034609", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004008 ;
    owl:annotatedTarget "Males exhibit defects in the prolonged, tonic, spicule extrusion through the vulva prior to sperm transfer." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002109", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004009 ;
    owl:annotatedTarget "Any variation in the mating process that includes the male stopping at the vulva (usually after backing) compared to control. In C. elegans general vulva location (stopping) requires the hook sensillum." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00002109", "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004010 ;
    owl:annotatedTarget "Any variation in the mating process that includes the male positioning his tail precisely over the vulva so that he may insert his spicules and ejaculate compared to control. In C. elegans precise vulva location (coordinating movement and tail positioning) requires the post cloacal sensillium and the spicules." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028400" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004011 ;
    owl:annotatedTarget "Any variation in the retraction of spicules after all sperm that exit the seminal vesicle have been released compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028400" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004012 ;
    owl:annotatedTarget "Any variation in the continued movement of sperm through the vas deferens, exiting the cloaca, compared to control. In C. elegans, when all sperm that exit the seminal vesicle have been released, the spicules retract into the male." .

[]
    oboInOwl:hasDbXref "WB:WBPaper00028400" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004013 ;
    owl:annotatedTarget "Any variation in the initial movement of sperm through the vas deferens, exiting the cloaca, compared to control." .

[]
    oboInOwl:hasDbXref "WB:WBPerson2021", "WB:WBPerson557" ;
    a owl:Axiom ;
    owl:annotatedProperty obo:IAO_0000115 ;
    owl:annotatedSource obo:WBPhenotype_0004014 ;
    owl:annotatedTarget "Any variation in the specific actions or reactions of a hermaphrodite after male contact during mating compared to control." .

